EP2010174A4 - Modulation pharmacologique des effets positifs des modulateurs des récepteurs ampa sur l'expression de neurotrophines - Google Patents
Modulation pharmacologique des effets positifs des modulateurs des récepteurs ampa sur l'expression de neurotrophinesInfo
- Publication number
- EP2010174A4 EP2010174A4 EP07760896A EP07760896A EP2010174A4 EP 2010174 A4 EP2010174 A4 EP 2010174A4 EP 07760896 A EP07760896 A EP 07760896A EP 07760896 A EP07760896 A EP 07760896A EP 2010174 A4 EP2010174 A4 EP 2010174A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- receptor modulator
- ampa receptor
- pharmacological modulation
- positive ampa
- modulator effects
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Psychology (AREA)
- Endocrinology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Reproductive Health (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US79396606P | 2006-04-20 | 2006-04-20 | |
PCT/US2007/066947 WO2007124348A2 (fr) | 2006-04-20 | 2007-04-19 | Modulation pharmacologique des effets positifs des modulateurs des récepteurs ampa sur l'expression de neurotrophines |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2010174A2 EP2010174A2 (fr) | 2009-01-07 |
EP2010174A4 true EP2010174A4 (fr) | 2012-05-09 |
Family
ID=38625729
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP07760896A Withdrawn EP2010174A4 (fr) | 2006-04-20 | 2007-04-19 | Modulation pharmacologique des effets positifs des modulateurs des récepteurs ampa sur l'expression de neurotrophines |
Country Status (6)
Country | Link |
---|---|
US (3) | US20090192199A1 (fr) |
EP (1) | EP2010174A4 (fr) |
JP (1) | JP2009534415A (fr) |
AU (1) | AU2007240469B2 (fr) |
CA (1) | CA2649844C (fr) |
WO (1) | WO2007124348A2 (fr) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008060375A2 (fr) * | 2006-10-06 | 2008-05-22 | The Regents Of The University Of Californina | Régulation positive de niveaux de bdnf pour atténuer un retard mental |
US20090239888A1 (en) * | 2008-02-12 | 2009-09-24 | Wisconsin Alumni Research Foundation | Methods for Inhibiting Amyloid Precursor Protein and Beta-Amyloid Production and Accumulation |
EP2301318B1 (fr) * | 2009-09-07 | 2011-11-16 | CLAAS Agrosystems GmbH & Co. KG | Système de commande pour véhicule agricole doté d'une remorque pour marchandises, véhicule agricole et procédé de commande de la remorque pour marchandises du véhicule agricole |
WO2011109398A2 (fr) | 2010-03-02 | 2011-09-09 | President And Fellows Of Harvard College | Procédés et compositions pour le traitement du syndrome d'angelman et des troubles du spectre autistique |
US20110257186A1 (en) * | 2010-04-15 | 2011-10-20 | Staubli Ursula V | Compositions and methods for treating visual disorders |
CN102276576B (zh) * | 2011-06-02 | 2013-08-14 | 西北工业大学 | 苯甲酰胺化合物及其制备方法 |
KR101439203B1 (ko) | 2013-03-29 | 2014-09-12 | 한림대학교 산학협력단 | Fk506 결합단백질 융합단백질과 피노밤을 포함하는 뇌 허혈손상 치료용 약제학적 조성물 |
US10300155B2 (en) | 2015-12-31 | 2019-05-28 | Washington University | Alpha-synuclein ligands |
WO2023164338A2 (fr) * | 2022-02-23 | 2023-08-31 | The Jonathan Hurt Living Trust | Compositions et méthodes de traitement de dysfonctionnements sexuels |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005104836A2 (fr) * | 2004-04-16 | 2005-11-10 | Albert Einstein College Of Medicine Of Yeshiva University | Modeles de drosophile pour des maladies affectant l'apprentissage et la memoire |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998011892A1 (fr) * | 1996-09-17 | 1998-03-26 | The Regents Of The University Of California | Modulation positive du recepteur ampa permettant d'ameliorer l'expression des facteurs neurotrophiques dans le cerveau |
-
2007
- 2007-04-19 CA CA2649844A patent/CA2649844C/fr not_active Expired - Fee Related
- 2007-04-19 AU AU2007240469A patent/AU2007240469B2/en not_active Ceased
- 2007-04-19 US US12/297,616 patent/US20090192199A1/en not_active Abandoned
- 2007-04-19 WO PCT/US2007/066947 patent/WO2007124348A2/fr active Application Filing
- 2007-04-19 EP EP07760896A patent/EP2010174A4/fr not_active Withdrawn
- 2007-04-19 JP JP2009506769A patent/JP2009534415A/ja active Pending
-
2011
- 2011-08-19 US US13/213,419 patent/US20110306601A1/en not_active Abandoned
-
2012
- 2012-10-17 US US13/654,366 patent/US20130123248A1/en not_active Abandoned
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005104836A2 (fr) * | 2004-04-16 | 2005-11-10 | Albert Einstein College Of Medicine Of Yeshiva University | Modeles de drosophile pour des maladies affectant l'apprentissage et la memoire |
Non-Patent Citations (1)
Title |
---|
O'NEILL M J ET AL: "Neutrophic actions of the novel AMPA receptor potentiator, LY404187, in rodent models of Parkinson's disease", EUROPEAN JOURNAL OF PHARMACOLOGY, ELSEVIER SCIENCE, NL, vol. 486, no. 2, 20 February 2004 (2004-02-20), pages 163 - 174, XP008130555, ISSN: 0014-2999, [retrieved on 20040121], DOI: 10.1016/J.EJPHAR.2003.12.023 * |
Also Published As
Publication number | Publication date |
---|---|
AU2007240469B2 (en) | 2011-01-20 |
EP2010174A2 (fr) | 2009-01-07 |
WO2007124348A2 (fr) | 2007-11-01 |
US20130123248A1 (en) | 2013-05-16 |
WO2007124348A3 (fr) | 2008-12-04 |
CA2649844C (fr) | 2011-07-05 |
CA2649844A1 (fr) | 2007-11-01 |
JP2009534415A (ja) | 2009-09-24 |
AU2007240469A1 (en) | 2007-11-01 |
US20090192199A1 (en) | 2009-07-30 |
US20110306601A1 (en) | 2011-12-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
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17P | Request for examination filed |
Effective date: 20081029 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR |
|
AX | Request for extension of the european patent |
Extension state: AL BA HR MK RS |
|
R17D | Deferred search report published (corrected) |
Effective date: 20081204 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61K 35/30 20060101ALI20081223BHEP Ipc: A61K 38/00 20060101ALI20081223BHEP Ipc: A61K 51/00 20060101AFI20081223BHEP |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20120405 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61P 25/28 20060101ALI20120330BHEP Ipc: A61K 31/4439 20060101ALI20120330BHEP Ipc: A61K 45/06 20060101ALI20120330BHEP Ipc: A61K 35/30 20060101ALI20120330BHEP Ipc: A61K 38/00 20060101ALI20120330BHEP Ipc: A61K 51/00 20060101AFI20120330BHEP |
|
DAX | Request for extension of the european patent (deleted) | ||
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
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18D | Application deemed to be withdrawn |
Effective date: 20121106 |