EP1960755A1 - Vorrichtung zur automatischen probennahme und bioluminometrischen analyse - Google Patents
Vorrichtung zur automatischen probennahme und bioluminometrischen analyseInfo
- Publication number
- EP1960755A1 EP1960755A1 EP06765552A EP06765552A EP1960755A1 EP 1960755 A1 EP1960755 A1 EP 1960755A1 EP 06765552 A EP06765552 A EP 06765552A EP 06765552 A EP06765552 A EP 06765552A EP 1960755 A1 EP1960755 A1 EP 1960755A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- fluid
- bioluminometric
- analyzed
- automatizing
- analysis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1004—Cleaning sample transfer devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/76—Chemiluminescence; Bioluminescence
- G01N21/763—Bioluminescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/84—Systems specially adapted for particular applications
- G01N21/88—Investigating the presence of flaws or contamination
- G01N21/94—Investigating contamination, e.g. dust
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/0099—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor comprising robots or similar manipulators
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1081—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane
Definitions
- the light emission is measured by a photonic count system based on a photo-multiplier and a digital count line.
- a further object of the present invention is to
- Another object of the present invention is to produce an automatic fluid sampling and bioluminomet ⁇
- an object of the present invention is to produce an automatic fluid sampling and bioluminomet- ric analysis device that assesses the bacterial charge of the analyzed fluid in order to compare it with a predetermined minimum threshold value.
- FIG. 2 shows a front view of a multifunction recirculation cylinder pertaining to the device according to the present invention.
- the head set 200 which is horizontally slidable, also provides a vertically sliding head 51 and a metering syringe 19 on it .
- a metering syringe slider 53 and a tube gripper 11 are also associated with the handling tower 21.
- a multifunction rod is associated to the head set 200 too.
- a container 8 for collecting used tubes is lodged, which container is connected to the console 1 by means of a discharge channel 9 ending at an inlet 10 on which used tubes are dropped by a gripper 11.
- an intake pipe 12 for the fluid to be ana- lyzed In the underside of the console 1 there are also lodged an intake pipe 12 for the fluid to be ana- lyzed, a discharge pipe 13 for the fluid to be ana- lyzed, a priming pump 14, a pipe for admitting washing fluid 15, a pipe for discharging washing fluid and air 16, a pipe for admitting pressurized air 17, and a tank 18 containing a substance suited for ster- ilization.
- a washing pulse pump Inside the console 1 are also lodged a washing pulse pump, a number of electrovalves belonging to the hydraulic and pneumatic circuits, and a system
- an inlet 30 in which a conduit 41 is provided to admit the sterilizing liquid from the tank 18.
- Said inlet leads to a clear cylinder 36 in which are provided a conduit 40 for the liquid to be analyzed, an upper valve 33 with its own motor 31 and a pre-filter valve 34 with its own motor 32.
- a filter 35 to block suspended particles is pro-
- a recirculation valve for the sample to be ana ⁇
- lyzed is also shown in fig. 2, which valve is shown at positions Hi 38 and Lo 37.
- the operation of the automatic sampling and bio- luminometric analysis device is the following.
- a metering syringe 19 is on the handling tower 21 of the head
- syringe 19 In that position, syringe 19 is enclosed into a sterile room which is protected from dust and inadvertent shocks .
- the priming pump 14 acting on the sewage dis- charge well 50 and connected to the intake pipe 12 causes continuous circulation of the water to be analyzed.
- the water continuously passing moves as a whirlpool (which movement is induced by the intake pipe, which is tangential to the compartment body) thus avoiding deposition of solid agglomerates.
- the pipes are smooth (above all the feed ones) and have a constant caliber to circumvent the same prob ⁇
- the upper compartment of the cylinder forms the withdrawing well for the sample to be analyzed.
- the well communicates with the lower compartment of the
- the withdrawing well When not in use, the withdrawing well has both the conical valve and the upper communication port of the syringe closed.
- the handling tower 21 places at the multifunction cylinder 4 in order to withdraw the sample to be analyzed.
- the movement of said tower is performed by an electric motor provided with an adapter and horizon ⁇
- the position references are absolute, with an acceleration and deceleration motor
- the sample is provided.
- reagents contained into compartments 6 and required for the subsequent luminometric analysis are injected into the tube, optionally performing a sterilization and drying step of the syringe 19 after every withdrawal, as needed.
- a sterilization and drying step of the sy- ringe into the cylinder 4 can be performed, always taking into consideration the reagent permanence times into the tube before the luminometric analysis, which must be constant .
- the tube is ready for being analyzed.
- the tower 21 is placed at the location of the rotating tube carrier 20 in order to take the tube by means of the gripper 11. Then, the head 51 rises again taking the tube with it, and the tower 21 moves to the luminometer 2 and the port thereof .
- the multifunction rod is withdrawn, the port of the luminometer 2 is opened and the multifunction rod enters a hole provided in the insertion carrier. By closing the port the luminometric measurement is automatically started, which allows to assess the sample bacterial concentration.
- a relays outlet can, if necessary, activate biocide introduc- tion or trigger an alarm indicating the critical threshold.
- the tower 21 of the head set 51 is placed on the location of the multifunction cylinder 4 and when the work is finished, a complete sterili- zation and cleaning cycle is performed.
- the device of the invention can be used to control a bacterial presence being greater than a minimum amount into an environment or
- the present invention can be therefore subjected
Landscapes
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plasma & Fusion (AREA)
- Engineering & Computer Science (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI20052407 ITMI20052407A1 (it) | 2005-12-16 | 2005-12-16 | Dispositivo automatico di campionamento e analisi bioluminometrica |
PCT/IB2006/001644 WO2007069005A1 (en) | 2005-12-16 | 2006-06-07 | Automatic sampling and bioluminometric analysis device |
Publications (1)
Publication Number | Publication Date |
---|---|
EP1960755A1 true EP1960755A1 (de) | 2008-08-27 |
Family
ID=36930334
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP06765552A Withdrawn EP1960755A1 (de) | 2005-12-16 | 2006-06-07 | Vorrichtung zur automatischen probennahme und bioluminometrischen analyse |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP1960755A1 (de) |
IT (1) | ITMI20052407A1 (de) |
WO (1) | WO2007069005A1 (de) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2922453B1 (fr) * | 2007-10-17 | 2011-01-14 | Millipore Corp | Procede de decontamination et systeme le mettant en oeuvre |
CN102066911B (zh) * | 2008-04-21 | 2013-05-29 | 霍尼韦尔国际公司 | 用于生物传感的基于萤光素-荧光素酶的微装置 |
JP4811797B2 (ja) * | 2010-01-26 | 2011-11-09 | 株式会社日立プラントテクノロジー | 発光測定装置の配管洗浄方法、発光測定装置の配管洗浄機構 |
CN101782427A (zh) * | 2010-03-12 | 2010-07-21 | 上海电机学院 | 照度计自动定位系统 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3520660A (en) * | 1966-09-09 | 1970-07-14 | Nasa | Light detection instrument |
US4140487A (en) * | 1975-12-10 | 1979-02-20 | Commonwealth Scientific And Industiral Research Organization | Method and apparatus for analysis of water |
FR2609171B1 (fr) * | 1986-12-24 | 1989-11-10 | Nivarox Sa | Appareil pour l'analyse photometrique d'echantillons liquides |
GB2211607A (en) * | 1987-10-29 | 1989-07-05 | Cardiff Energy & Resources | Injection systems for luminometers |
-
2005
- 2005-12-16 IT ITMI20052407 patent/ITMI20052407A1/it unknown
-
2006
- 2006-06-07 EP EP06765552A patent/EP1960755A1/de not_active Withdrawn
- 2006-06-07 WO PCT/IB2006/001644 patent/WO2007069005A1/en active Application Filing
Non-Patent Citations (1)
Title |
---|
See references of WO2007069005A1 * |
Also Published As
Publication number | Publication date |
---|---|
ITMI20052407A1 (it) | 2007-06-17 |
WO2007069005A1 (en) | 2007-06-21 |
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Legal Events
Date | Code | Title | Description |
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PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
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17P | Request for examination filed |
Effective date: 20080528 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR |
|
DAX | Request for extension of the european patent (deleted) | ||
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20160105 |