EP1960755A1 - Vorrichtung zur automatischen probennahme und bioluminometrischen analyse - Google Patents

Vorrichtung zur automatischen probennahme und bioluminometrischen analyse

Info

Publication number
EP1960755A1
EP1960755A1 EP06765552A EP06765552A EP1960755A1 EP 1960755 A1 EP1960755 A1 EP 1960755A1 EP 06765552 A EP06765552 A EP 06765552A EP 06765552 A EP06765552 A EP 06765552A EP 1960755 A1 EP1960755 A1 EP 1960755A1
Authority
EP
European Patent Office
Prior art keywords
fluid
bioluminometric
analyzed
automatizing
analysis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP06765552A
Other languages
English (en)
French (fr)
Inventor
Giorgio Bellini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Star Ecotronics Srl
Original Assignee
Star Ecotronics Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Star Ecotronics Srl filed Critical Star Ecotronics Srl
Publication of EP1960755A1 publication Critical patent/EP1960755A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1004Cleaning sample transfer devices
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/76Chemiluminescence; Bioluminescence
    • G01N21/763Bioluminescence
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84Systems specially adapted for particular applications
    • G01N21/88Investigating the presence of flaws or contamination
    • G01N21/94Investigating contamination, e.g. dust
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0099Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor comprising robots or similar manipulators
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1081Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane

Definitions

  • the light emission is measured by a photonic count system based on a photo-multiplier and a digital count line.
  • a further object of the present invention is to
  • Another object of the present invention is to produce an automatic fluid sampling and bioluminomet ⁇
  • an object of the present invention is to produce an automatic fluid sampling and bioluminomet- ric analysis device that assesses the bacterial charge of the analyzed fluid in order to compare it with a predetermined minimum threshold value.
  • FIG. 2 shows a front view of a multifunction recirculation cylinder pertaining to the device according to the present invention.
  • the head set 200 which is horizontally slidable, also provides a vertically sliding head 51 and a metering syringe 19 on it .
  • a metering syringe slider 53 and a tube gripper 11 are also associated with the handling tower 21.
  • a multifunction rod is associated to the head set 200 too.
  • a container 8 for collecting used tubes is lodged, which container is connected to the console 1 by means of a discharge channel 9 ending at an inlet 10 on which used tubes are dropped by a gripper 11.
  • an intake pipe 12 for the fluid to be ana- lyzed In the underside of the console 1 there are also lodged an intake pipe 12 for the fluid to be ana- lyzed, a discharge pipe 13 for the fluid to be ana- lyzed, a priming pump 14, a pipe for admitting washing fluid 15, a pipe for discharging washing fluid and air 16, a pipe for admitting pressurized air 17, and a tank 18 containing a substance suited for ster- ilization.
  • a washing pulse pump Inside the console 1 are also lodged a washing pulse pump, a number of electrovalves belonging to the hydraulic and pneumatic circuits, and a system
  • an inlet 30 in which a conduit 41 is provided to admit the sterilizing liquid from the tank 18.
  • Said inlet leads to a clear cylinder 36 in which are provided a conduit 40 for the liquid to be analyzed, an upper valve 33 with its own motor 31 and a pre-filter valve 34 with its own motor 32.
  • a filter 35 to block suspended particles is pro-
  • a recirculation valve for the sample to be ana ⁇
  • lyzed is also shown in fig. 2, which valve is shown at positions Hi 38 and Lo 37.
  • the operation of the automatic sampling and bio- luminometric analysis device is the following.
  • a metering syringe 19 is on the handling tower 21 of the head
  • syringe 19 In that position, syringe 19 is enclosed into a sterile room which is protected from dust and inadvertent shocks .
  • the priming pump 14 acting on the sewage dis- charge well 50 and connected to the intake pipe 12 causes continuous circulation of the water to be analyzed.
  • the water continuously passing moves as a whirlpool (which movement is induced by the intake pipe, which is tangential to the compartment body) thus avoiding deposition of solid agglomerates.
  • the pipes are smooth (above all the feed ones) and have a constant caliber to circumvent the same prob ⁇
  • the upper compartment of the cylinder forms the withdrawing well for the sample to be analyzed.
  • the well communicates with the lower compartment of the
  • the withdrawing well When not in use, the withdrawing well has both the conical valve and the upper communication port of the syringe closed.
  • the handling tower 21 places at the multifunction cylinder 4 in order to withdraw the sample to be analyzed.
  • the movement of said tower is performed by an electric motor provided with an adapter and horizon ⁇
  • the position references are absolute, with an acceleration and deceleration motor
  • the sample is provided.
  • reagents contained into compartments 6 and required for the subsequent luminometric analysis are injected into the tube, optionally performing a sterilization and drying step of the syringe 19 after every withdrawal, as needed.
  • a sterilization and drying step of the sy- ringe into the cylinder 4 can be performed, always taking into consideration the reagent permanence times into the tube before the luminometric analysis, which must be constant .
  • the tube is ready for being analyzed.
  • the tower 21 is placed at the location of the rotating tube carrier 20 in order to take the tube by means of the gripper 11. Then, the head 51 rises again taking the tube with it, and the tower 21 moves to the luminometer 2 and the port thereof .
  • the multifunction rod is withdrawn, the port of the luminometer 2 is opened and the multifunction rod enters a hole provided in the insertion carrier. By closing the port the luminometric measurement is automatically started, which allows to assess the sample bacterial concentration.
  • a relays outlet can, if necessary, activate biocide introduc- tion or trigger an alarm indicating the critical threshold.
  • the tower 21 of the head set 51 is placed on the location of the multifunction cylinder 4 and when the work is finished, a complete sterili- zation and cleaning cycle is performed.
  • the device of the invention can be used to control a bacterial presence being greater than a minimum amount into an environment or
  • the present invention can be therefore subjected

Landscapes

  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Engineering & Computer Science (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
EP06765552A 2005-12-16 2006-06-07 Vorrichtung zur automatischen probennahme und bioluminometrischen analyse Withdrawn EP1960755A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI20052407 ITMI20052407A1 (it) 2005-12-16 2005-12-16 Dispositivo automatico di campionamento e analisi bioluminometrica
PCT/IB2006/001644 WO2007069005A1 (en) 2005-12-16 2006-06-07 Automatic sampling and bioluminometric analysis device

Publications (1)

Publication Number Publication Date
EP1960755A1 true EP1960755A1 (de) 2008-08-27

Family

ID=36930334

Family Applications (1)

Application Number Title Priority Date Filing Date
EP06765552A Withdrawn EP1960755A1 (de) 2005-12-16 2006-06-07 Vorrichtung zur automatischen probennahme und bioluminometrischen analyse

Country Status (3)

Country Link
EP (1) EP1960755A1 (de)
IT (1) ITMI20052407A1 (de)
WO (1) WO2007069005A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2922453B1 (fr) * 2007-10-17 2011-01-14 Millipore Corp Procede de decontamination et systeme le mettant en oeuvre
CN102066911B (zh) * 2008-04-21 2013-05-29 霍尼韦尔国际公司 用于生物传感的基于萤光素-荧光素酶的微装置
JP4811797B2 (ja) * 2010-01-26 2011-11-09 株式会社日立プラントテクノロジー 発光測定装置の配管洗浄方法、発光測定装置の配管洗浄機構
CN101782427A (zh) * 2010-03-12 2010-07-21 上海电机学院 照度计自动定位系统

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3520660A (en) * 1966-09-09 1970-07-14 Nasa Light detection instrument
US4140487A (en) * 1975-12-10 1979-02-20 Commonwealth Scientific And Industiral Research Organization Method and apparatus for analysis of water
FR2609171B1 (fr) * 1986-12-24 1989-11-10 Nivarox Sa Appareil pour l'analyse photometrique d'echantillons liquides
GB2211607A (en) * 1987-10-29 1989-07-05 Cardiff Energy & Resources Injection systems for luminometers

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO2007069005A1 *

Also Published As

Publication number Publication date
ITMI20052407A1 (it) 2007-06-17
WO2007069005A1 (en) 2007-06-21

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