EP1957629A4 - Colonne d'affinité pour de multiples analytes - Google Patents

Colonne d'affinité pour de multiples analytes Download PDF

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Publication number
EP1957629A4
EP1957629A4 EP06844414.0A EP06844414A EP1957629A4 EP 1957629 A4 EP1957629 A4 EP 1957629A4 EP 06844414 A EP06844414 A EP 06844414A EP 1957629 A4 EP1957629 A4 EP 1957629A4
Authority
EP
European Patent Office
Prior art keywords
affinity column
analyte affinity
analyte
column
affinity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP06844414.0A
Other languages
German (de)
English (en)
Other versions
EP1957629A2 (fr
EP1957629B1 (fr
Inventor
Nancy Ann Zabe
Christopher John Basker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Waters Technologies Corp
Original Assignee
Waters Technologies Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Waters Technologies Corp filed Critical Waters Technologies Corp
Priority to EP06844414.0A priority Critical patent/EP1957629B1/fr
Publication of EP1957629A2 publication Critical patent/EP1957629A2/fr
Publication of EP1957629A4 publication Critical patent/EP1957629A4/fr
Application granted granted Critical
Publication of EP1957629B1 publication Critical patent/EP1957629B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3804—Affinity chromatography
    • B01D15/3809—Affinity chromatography of the antigen-antibody type, e.g. protein A, G, L chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/262—Synthetic macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. obtained by polycondensation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/265—Synthetic macromolecular compounds modified or post-treated polymers
    • B01J20/267—Cross-linked polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28002—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their physical properties
    • B01J20/28004—Sorbent size or size distribution, e.g. particle size
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B01J20/28052—Several layers of identical or different sorbents stacked in a housing, e.g. in a column
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3206—Organic carriers, supports or substrates
    • B01J20/3208—Polymeric carriers, supports or substrates
    • B01J20/3212—Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/3272—Polymers obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B01J20/3274—Proteins, nucleic acids, polysaccharides, antibodies or antigens
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3289—Coatings involving more than one layer of same or different nature
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56961—Plant cells or fungi
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00—Aspects relating to sorbent materials
    • B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/54—Sorbents specially adapted for analytical or investigative chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00—Aspects relating to sorbent materials
    • B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/58—Use in a single column

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Botany (AREA)
  • Virology (AREA)
  • Mycology (AREA)
  • Peptides Or Proteins (AREA)
EP06844414.0A 2005-11-17 2006-11-17 Colonne d'affinité pour de multiples analytes Active EP1957629B1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP06844414.0A EP1957629B1 (fr) 2005-11-17 2006-11-17 Colonne d'affinité pour de multiples analytes

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US73833005P 2005-11-17 2005-11-17
EP05028102A EP1787699A1 (fr) 2005-11-17 2005-12-21 Colonne par affinité multi-analytes
PCT/US2006/044739 WO2007059316A2 (fr) 2005-11-17 2006-11-17 Colonne d'affinité pour de multiples analytes
EP06844414.0A EP1957629B1 (fr) 2005-11-17 2006-11-17 Colonne d'affinité pour de multiples analytes

Publications (3)

Publication Number Publication Date
EP1957629A2 EP1957629A2 (fr) 2008-08-20
EP1957629A4 true EP1957629A4 (fr) 2017-10-18
EP1957629B1 EP1957629B1 (fr) 2021-01-13

Family

ID=35929543

Family Applications (2)

Application Number Title Priority Date Filing Date
EP05028102A Withdrawn EP1787699A1 (fr) 2005-11-17 2005-12-21 Colonne par affinité multi-analytes
EP06844414.0A Active EP1957629B1 (fr) 2005-11-17 2006-11-17 Colonne d'affinité pour de multiples analytes

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP05028102A Withdrawn EP1787699A1 (fr) 2005-11-17 2005-12-21 Colonne par affinité multi-analytes

Country Status (4)

Country Link
US (1) US8198032B2 (fr)
EP (2) EP1787699A1 (fr)
CA (1) CA2629472C (fr)
WO (1) WO2007059316A2 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1787699A1 (fr) 2005-11-17 2007-05-23 Vicam, L.P. Colonne par affinité multi-analytes
GB2466536A (en) * 2009-08-25 2010-06-30 Simon James Bevis Immunoaffinity column for detection of deoxynivalenol, deoxynivalenol, T2 toxin and HT2 toxin
GB2476525A (en) * 2010-08-17 2011-06-29 Simon James Bevis Immunoaffinity column for detection of Aflatoxins B1, B2, G1, G2, Ochratoxin A and Fumonisins B1, B2
CA2886713A1 (fr) * 2011-10-12 2013-04-18 The University Of North Carolina At Chapel Hill Billes d'inhibiteur de kinase multiplexees et leurs utilisations
CN102590380A (zh) * 2012-02-10 2012-07-18 江苏省农业科学院 一种谷物中结合态脱氧雪腐镰刀菌烯醇含量的检测方法
CN103792356A (zh) * 2012-11-04 2014-05-14 江苏维赛科技生物发展有限公司 检测伏马毒素的elisa试剂盒的制备及检测方法
CN104311636B (zh) * 2013-03-06 2017-05-17 南昌大学 一种模拟伏马菌素b1抗原模拟表位及其用途
TWI833397B (zh) * 2022-10-20 2024-02-21 巨研科技股份有限公司 萃取淨化農產品中黴菌毒素殘留的套件以及使用該套件從農產品樣品取得檢液原液的方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5178832A (en) * 1987-09-28 1993-01-12 The Texas A&M University System Selective immobilization and detection of mycotoxins in solution

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4859611A (en) * 1985-02-28 1989-08-22 Massachusetts Institute Of Technology Affinity column and process for detection of low molecular weight toxic substances
US4818687A (en) * 1985-02-28 1989-04-04 Massachusetts Institute Of Technology Affinity column and process for detection of low molecular weight toxic substances
US5707818A (en) * 1994-12-13 1998-01-13 Bsi Corporation Device and method for simultaneously performing multiple competitive immunoassays
CZ297165B6 (cs) * 1997-04-21 2006-09-13 Randox Laboratories Ltd. A British Company Of Ardmore Zpusob výroby zarízení s pevnou fází k provádení multianalytních rozboru
WO2002065115A2 (fr) * 2001-02-13 2002-08-22 Universiteit Gent Dispositif et procede pour detecter la presence d'un analyte
US20070048787A1 (en) * 2005-08-26 2007-03-01 Vicam, L.P. Multi-analyte affinity column
ATE548093T1 (de) * 2005-11-17 2012-03-15 Waters Investments Ltd Mehranalyt-affinitätssäule zur analyse von aflatoxin, fumonisin, ochratoxin und zearalenon
EP1787700B1 (fr) 2005-11-17 2012-03-07 Waters Investments Limited Colonne par affinité multi-analyte pour l'analyse d' aflatoxine, d'ochratoxine , de zearalenone et de deoxynivalenole
EP1787699A1 (fr) 2005-11-17 2007-05-23 Vicam, L.P. Colonne par affinité multi-analytes

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5178832A (en) * 1987-09-28 1993-01-12 The Texas A&M University System Selective immobilization and detection of mycotoxins in solution

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
CHAN ET AL: "Simultaneous determination of aflatoxins and ochratoxin A in food using a fully automated immunoaffinity column clean-up and liquid chromatography-fluorescence detection", JOURNAL OF CHROMATOGRAP, ELSEVIER, AMSTERDAM, NL, vol. 1059, no. 1-2, 3 December 2004 (2004-12-03), pages 13 - 16, XP005003904, ISSN: 0021-9673, DOI: 10.1016/J.CHROMA.2004.09.096 *
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1 January 1992 (1992-01-01), ISOHATA E ET AL: "SIMULTANEOUS ANALYSIS OF SEVERAL MYCOTOXINS IN GRAINS BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY STUDIES ON CHEMICAL ANALYSIS OF MYCOTOXINS PART XXII", XP002370856, retrieved from BIOSIS Database accession no. PREV199294102752 *
GOEBEL R ET AL: "SIMULTANEOUS DETERMINATION OF AFLATOXINS, OCHRATOXIN A, AND ZEARALENONE IN GRAINS BY NEW IMMUNOAFFINITY COLUMN LIQUID CHROMATOGRAPHY", JOURNAL OF AOAC INTERNATI, AOAC INTERNATIONAL, ARLINGTON, VA, US, vol. 87, no. 2, 1 January 2004 (2004-01-01), pages 411 - 416, XP008061200, ISSN: 1060-3271 *
ISOHATA E ET AL: "[Studies on chemical analysis of mycotoxin (XXI). A rapid analytical method for aflatoxins by immunoaffinity column chromatography and high performance liquid chromatography]", MEDLINE, 1 January 1990 (1990-01-01), XP002370857 *
OFITSEROVA M ET AL: "Multi-Residue Mycotoxin Analysis", INTERNET CITATION, 2004, XP002377222, Retrieved from the Internet <URL:http://www.pickeringlabs.com.cn/support/appnotes/MA203.pdf> [retrieved on 20060418] *
SCOTT P M ET AL: "APPLICATION OF IMMUNOAFFINITY COLUMNS TO MYCOTOXIN ANALYSIS", JOURNAL OF AOAC INTERNATI, AOAC INTERNATIONAL, ARLINGTON, VA, US, vol. 80, no. 5, 1 September 1997 (1997-09-01), pages 941 - 949, XP008061305, ISSN: 1060-3271 *
VISCONTI A ET AL: "Analysis of T-2 and HT-2 toxins in cereal grains by immunoaffinity clean-up and liquid chromatography with fluorescence detection", JOURNAL OF CHROMATOGRAPHY A, ELSEVIER, AMSTERDAM, NL, vol. 1075, no. 1-2, 20 May 2005 (2005-05-20), pages 151 - 158, XP027723170, ISSN: 0021-9673, [retrieved on 20050520] *

Also Published As

Publication number Publication date
WO2007059316A2 (fr) 2007-05-24
WO2007059316A3 (fr) 2007-12-13
US20090035786A1 (en) 2009-02-05
EP1957629A2 (fr) 2008-08-20
CA2629472A1 (fr) 2007-05-24
US8198032B2 (en) 2012-06-12
EP1957629B1 (fr) 2021-01-13
EP1787699A1 (fr) 2007-05-23
CA2629472C (fr) 2016-05-24

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