EP1928468A4 - Therapie par estriol pour maladies et troubles neurodegeneratifs et autoimmuns - Google Patents
Therapie par estriol pour maladies et troubles neurodegeneratifs et autoimmunsInfo
- Publication number
- EP1928468A4 EP1928468A4 EP06815340A EP06815340A EP1928468A4 EP 1928468 A4 EP1928468 A4 EP 1928468A4 EP 06815340 A EP06815340 A EP 06815340A EP 06815340 A EP06815340 A EP 06815340A EP 1928468 A4 EP1928468 A4 EP 1928468A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- autoimmune
- disorders
- neurodegenerative diseases
- estriol
- therapy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
- A61P5/16—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4 for decreasing, blocking or antagonising the activity of the thyroid hormones
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- Endocrinology (AREA)
- Communicable Diseases (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US72097105P | 2005-09-26 | 2005-09-26 | |
US83352706P | 2006-07-26 | 2006-07-26 | |
PCT/US2006/037259 WO2007038435A2 (fr) | 2005-09-26 | 2006-09-26 | Therapie par estriol pour maladies et troubles neurodegeneratifs et autoimmuns |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1928468A2 EP1928468A2 (fr) | 2008-06-11 |
EP1928468A4 true EP1928468A4 (fr) | 2010-12-08 |
Family
ID=37900361
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP06815340A Withdrawn EP1928468A4 (fr) | 2005-09-26 | 2006-09-26 | Therapie par estriol pour maladies et troubles neurodegeneratifs et autoimmuns |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1928468A4 (fr) |
JP (1) | JP2009510070A (fr) |
AU (1) | AU2006294826A1 (fr) |
CA (1) | CA2623905A1 (fr) |
WO (1) | WO2007038435A2 (fr) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20120328566A9 (en) * | 2001-04-25 | 2012-12-27 | Rhonda R Voskuhl | Estrogen receptor ligand treatment for neurodegenerative diseases |
US20130203722A1 (en) | 2006-09-26 | 2013-08-08 | Rhonda R. Voskuhl | Estriol therapy for autoimmune and neurodegenerative disease and disorders |
US8658627B2 (en) | 2001-04-25 | 2014-02-25 | The Regents Of The University Of California | Pregnancy hormone combination for treatment of autoimmune diseases |
US6936599B2 (en) | 2001-04-25 | 2005-08-30 | The Regents Of The University Of California | Estriol therapy for multiple sclerosis and other autoimmune diseases |
CA2623839C (fr) * | 2005-09-26 | 2013-12-17 | The Regents Of The University Of California | Therapie par estriol pour maladie des troubles auto-immuns et neurodegeneratifs |
US9763992B2 (en) | 2014-02-13 | 2017-09-19 | Father Flanagan's Boys' Home | Treatment of noise induced hearing loss |
ES2959603T3 (es) | 2014-04-28 | 2024-02-27 | Univ California | Envase farmacéutico para terapia con estriol para el tratamiento de la esclerosis múltiple |
US10799512B2 (en) | 2014-04-28 | 2020-10-13 | The Regents Of The University Of California | Estrogen combination for treatment of multiple sclerosis |
EP3188735A4 (fr) | 2014-09-02 | 2018-01-24 | The Regents of the University of California | Thérapie oestrogénique pour traitement l'atrophie de la matière grise cérébrale et le handicap associé |
EP3189026B1 (fr) | 2014-09-02 | 2020-07-22 | The Regents of The University of California | Traitement par ligand du récepteur des oestrogènes contre les maladies neurodégénératives |
ES2957543T3 (es) | 2014-09-29 | 2024-01-22 | Univ California | Composiciones y métodos para mantener la función cognitiva |
US10406169B2 (en) | 2015-03-30 | 2019-09-10 | The Regents Of The University Of California | Methods of monitoring estriol therapy |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5554601A (en) * | 1993-11-05 | 1996-09-10 | University Of Florida | Methods for neuroprotection |
WO1997008188A1 (fr) * | 1995-08-23 | 1997-03-06 | Astra Aktiebolag | Nouveaux oestrogenes |
US20010016325A1 (en) * | 1999-12-01 | 2001-08-23 | Mobley William C. | Activation of novel estrogen receptor supports and neuronal viability and function |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2002237126A1 (en) * | 2001-03-02 | 2002-09-19 | Stem Cell Therapeutics Inc. | Use of ovarian hormone for increasing neural stem cell number |
US6936599B2 (en) * | 2001-04-25 | 2005-08-30 | The Regents Of The University Of California | Estriol therapy for multiple sclerosis and other autoimmune diseases |
JP4801868B2 (ja) * | 2002-02-25 | 2011-10-26 | 晃史 山口 | 全身性エリテマトーデス発病抑制薬 |
CA2623839C (fr) * | 2005-09-26 | 2013-12-17 | The Regents Of The University Of California | Therapie par estriol pour maladie des troubles auto-immuns et neurodegeneratifs |
-
2006
- 2006-09-26 CA CA002623905A patent/CA2623905A1/fr not_active Abandoned
- 2006-09-26 EP EP06815340A patent/EP1928468A4/fr not_active Withdrawn
- 2006-09-26 WO PCT/US2006/037259 patent/WO2007038435A2/fr active Application Filing
- 2006-09-26 JP JP2008533482A patent/JP2009510070A/ja active Pending
- 2006-09-26 AU AU2006294826A patent/AU2006294826A1/en not_active Abandoned
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5554601A (en) * | 1993-11-05 | 1996-09-10 | University Of Florida | Methods for neuroprotection |
WO1997008188A1 (fr) * | 1995-08-23 | 1997-03-06 | Astra Aktiebolag | Nouveaux oestrogenes |
US20010016325A1 (en) * | 1999-12-01 | 2001-08-23 | Mobley William C. | Activation of novel estrogen receptor supports and neuronal viability and function |
Non-Patent Citations (8)
Title |
---|
ANSAR AHMED S ET AL: "The effects of female sex steroids on the development of autoimmune thyroiditis in thymectomized and irradiated rats.", CLINICAL AND EXPERIMENTAL IMMUNOLOGY NOV 1983 LNKD- PUBMED:6360435, vol. 54, no. 2, November 1983 (1983-11-01), pages 351 - 358, ISSN: 0009-9104 * |
CHAN C-C ET AL: "A correlation of pregnancy term, disease activity, serum female hormones, and cytokines in uveitis.", THE BRITISH JOURNAL OF OPHTHALMOLOGY DEC 2004 LNKD- PUBMED:15548800, vol. 88, no. 12, December 2004 (2004-12-01), pages 1506 - 1509, ISSN: 0007-1161 * |
EL-ETR M ET AL: "Steroid hormones in multiple sclerosis", JOURNAL OF NEUROLOGICAL SCIENCES, ELSEVIER SCIENTIFIC PUBLISHING CO, AMSTERDAM, NL LNKD- DOI:10.1016/J.JNS.2005.03.004, vol. 233, no. 1-2, 15 June 2005 (2005-06-15), pages 49 - 54, XP004932279, ISSN: 0022-510X * |
LIISA A M GALEA ET AL: "Estradiol alleviates depressive-like symptoms in novel animal model of post-partum depression", BEHAVIOURAL BRAIN RESEARCH, ELSEVIER, AMSTERDAM, NL LNKD- DOI:10.1016/S0166-4328(01)00170-X, vol. 122, no. 1, 1 January 2001 (2001-01-01), pages 1 - 9, XP008082590, ISSN: 0166-4328 * |
MURASE JENNY E ET AL: "Hormonal effect on psoriasis in pregnancy and post partum.", ARCHIVES OF DERMATOLOGY MAY 2005 LNKD- PUBMED:15897382, vol. 141, no. 5, May 2005 (2005-05-01), pages 601 - 606, ISSN: 0003-987X * |
OFFNER, HALINA: "Neuroimmunoprotective effects of estrogen and derivatives in experimental autoimmune encephalomyelitis: Therapeutic implications for multiple sclerosis", JOURNAL OF NEUROSCIENCE RESEARCH ( 2004 ), 78(5), 603-624 CODEN: JNREDK; ISSN: 0360-4012, 28 October 2004 (2004-10-28), XP002605593 * |
RATKAY L G ET AL: "Evaluation of a model for post-partum arthritis and the role of oestrogen in prevention of MRL-lpr associated rheumatic conditions", CLINICAL AND EXPERIMENTAL IMMUNOLOGY, vol. 98, no. 1, 1994, pages 52 - 59, XP002606112, ISSN: 0009-9104 * |
SAMANTHA S SOLDAN ET AL: "Immune modulation in multiple sclerosis patients treated with the pregnancy hormone estriol", JOURNAL OF IMMUNOLOGY, AMERICAN ASSOCIATION OF IMMUNOLOGISTS, US, vol. 171, no. 11, 1 December 2003 (2003-12-01), pages 6267 - 6268, XP008126547, ISSN: 0022-1767 * |
Also Published As
Publication number | Publication date |
---|---|
WO2007038435A2 (fr) | 2007-04-05 |
JP2009510070A (ja) | 2009-03-12 |
AU2006294826A1 (en) | 2007-04-05 |
WO2007038435A3 (fr) | 2007-06-28 |
EP1928468A2 (fr) | 2008-06-11 |
CA2623905A1 (fr) | 2007-04-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20080331 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20101102 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61K 31/565 20060101ALI20101022BHEP Ipc: G01N 33/00 20060101AFI20101022BHEP Ipc: A61K 31/566 20060101ALI20101022BHEP Ipc: A61K 31/568 20060101ALI20101022BHEP Ipc: A61K 45/06 20060101ALI20101022BHEP |
|
RA4 | Supplementary search report drawn up and despatched (corrected) |
Effective date: 20101110 |
|
17Q | First examination report despatched |
Effective date: 20120703 |
|
DAX | Request for extension of the european patent (deleted) | ||
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20121114 |