EP1928468A4 - Therapie par estriol pour maladies et troubles neurodegeneratifs et autoimmuns - Google Patents

Therapie par estriol pour maladies et troubles neurodegeneratifs et autoimmuns

Info

Publication number
EP1928468A4
EP1928468A4 EP06815340A EP06815340A EP1928468A4 EP 1928468 A4 EP1928468 A4 EP 1928468A4 EP 06815340 A EP06815340 A EP 06815340A EP 06815340 A EP06815340 A EP 06815340A EP 1928468 A4 EP1928468 A4 EP 1928468A4
Authority
EP
European Patent Office
Prior art keywords
autoimmune
disorders
neurodegenerative diseases
estriol
therapy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP06815340A
Other languages
German (de)
English (en)
Other versions
EP1928468A2 (fr
Inventor
Rhonda R Voskuhl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
Original Assignee
University of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California filed Critical University of California
Publication of EP1928468A2 publication Critical patent/EP1928468A2/fr
Publication of EP1928468A4 publication Critical patent/EP1928468A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • A61P5/16—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4 for decreasing, blocking or antagonising the activity of the thyroid hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Communicable Diseases (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EP06815340A 2005-09-26 2006-09-26 Therapie par estriol pour maladies et troubles neurodegeneratifs et autoimmuns Withdrawn EP1928468A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US72097105P 2005-09-26 2005-09-26
US83352706P 2006-07-26 2006-07-26
PCT/US2006/037259 WO2007038435A2 (fr) 2005-09-26 2006-09-26 Therapie par estriol pour maladies et troubles neurodegeneratifs et autoimmuns

Publications (2)

Publication Number Publication Date
EP1928468A2 EP1928468A2 (fr) 2008-06-11
EP1928468A4 true EP1928468A4 (fr) 2010-12-08

Family

ID=37900361

Family Applications (1)

Application Number Title Priority Date Filing Date
EP06815340A Withdrawn EP1928468A4 (fr) 2005-09-26 2006-09-26 Therapie par estriol pour maladies et troubles neurodegeneratifs et autoimmuns

Country Status (5)

Country Link
EP (1) EP1928468A4 (fr)
JP (1) JP2009510070A (fr)
AU (1) AU2006294826A1 (fr)
CA (1) CA2623905A1 (fr)
WO (1) WO2007038435A2 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120328566A9 (en) * 2001-04-25 2012-12-27 Rhonda R Voskuhl Estrogen receptor ligand treatment for neurodegenerative diseases
US20130203722A1 (en) 2006-09-26 2013-08-08 Rhonda R. Voskuhl Estriol therapy for autoimmune and neurodegenerative disease and disorders
US8658627B2 (en) 2001-04-25 2014-02-25 The Regents Of The University Of California Pregnancy hormone combination for treatment of autoimmune diseases
US6936599B2 (en) 2001-04-25 2005-08-30 The Regents Of The University Of California Estriol therapy for multiple sclerosis and other autoimmune diseases
CA2623839C (fr) * 2005-09-26 2013-12-17 The Regents Of The University Of California Therapie par estriol pour maladie des troubles auto-immuns et neurodegeneratifs
US9763992B2 (en) 2014-02-13 2017-09-19 Father Flanagan's Boys' Home Treatment of noise induced hearing loss
ES2959603T3 (es) 2014-04-28 2024-02-27 Univ California Envase farmacéutico para terapia con estriol para el tratamiento de la esclerosis múltiple
US10799512B2 (en) 2014-04-28 2020-10-13 The Regents Of The University Of California Estrogen combination for treatment of multiple sclerosis
EP3188735A4 (fr) 2014-09-02 2018-01-24 The Regents of the University of California Thérapie oestrogénique pour traitement l'atrophie de la matière grise cérébrale et le handicap associé
EP3189026B1 (fr) 2014-09-02 2020-07-22 The Regents of The University of California Traitement par ligand du récepteur des oestrogènes contre les maladies neurodégénératives
ES2957543T3 (es) 2014-09-29 2024-01-22 Univ California Composiciones y métodos para mantener la función cognitiva
US10406169B2 (en) 2015-03-30 2019-09-10 The Regents Of The University Of California Methods of monitoring estriol therapy

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5554601A (en) * 1993-11-05 1996-09-10 University Of Florida Methods for neuroprotection
WO1997008188A1 (fr) * 1995-08-23 1997-03-06 Astra Aktiebolag Nouveaux oestrogenes
US20010016325A1 (en) * 1999-12-01 2001-08-23 Mobley William C. Activation of novel estrogen receptor supports and neuronal viability and function

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002237126A1 (en) * 2001-03-02 2002-09-19 Stem Cell Therapeutics Inc. Use of ovarian hormone for increasing neural stem cell number
US6936599B2 (en) * 2001-04-25 2005-08-30 The Regents Of The University Of California Estriol therapy for multiple sclerosis and other autoimmune diseases
JP4801868B2 (ja) * 2002-02-25 2011-10-26 晃史 山口 全身性エリテマトーデス発病抑制薬
CA2623839C (fr) * 2005-09-26 2013-12-17 The Regents Of The University Of California Therapie par estriol pour maladie des troubles auto-immuns et neurodegeneratifs

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5554601A (en) * 1993-11-05 1996-09-10 University Of Florida Methods for neuroprotection
WO1997008188A1 (fr) * 1995-08-23 1997-03-06 Astra Aktiebolag Nouveaux oestrogenes
US20010016325A1 (en) * 1999-12-01 2001-08-23 Mobley William C. Activation of novel estrogen receptor supports and neuronal viability and function

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
ANSAR AHMED S ET AL: "The effects of female sex steroids on the development of autoimmune thyroiditis in thymectomized and irradiated rats.", CLINICAL AND EXPERIMENTAL IMMUNOLOGY NOV 1983 LNKD- PUBMED:6360435, vol. 54, no. 2, November 1983 (1983-11-01), pages 351 - 358, ISSN: 0009-9104 *
CHAN C-C ET AL: "A correlation of pregnancy term, disease activity, serum female hormones, and cytokines in uveitis.", THE BRITISH JOURNAL OF OPHTHALMOLOGY DEC 2004 LNKD- PUBMED:15548800, vol. 88, no. 12, December 2004 (2004-12-01), pages 1506 - 1509, ISSN: 0007-1161 *
EL-ETR M ET AL: "Steroid hormones in multiple sclerosis", JOURNAL OF NEUROLOGICAL SCIENCES, ELSEVIER SCIENTIFIC PUBLISHING CO, AMSTERDAM, NL LNKD- DOI:10.1016/J.JNS.2005.03.004, vol. 233, no. 1-2, 15 June 2005 (2005-06-15), pages 49 - 54, XP004932279, ISSN: 0022-510X *
LIISA A M GALEA ET AL: "Estradiol alleviates depressive-like symptoms in novel animal model of post-partum depression", BEHAVIOURAL BRAIN RESEARCH, ELSEVIER, AMSTERDAM, NL LNKD- DOI:10.1016/S0166-4328(01)00170-X, vol. 122, no. 1, 1 January 2001 (2001-01-01), pages 1 - 9, XP008082590, ISSN: 0166-4328 *
MURASE JENNY E ET AL: "Hormonal effect on psoriasis in pregnancy and post partum.", ARCHIVES OF DERMATOLOGY MAY 2005 LNKD- PUBMED:15897382, vol. 141, no. 5, May 2005 (2005-05-01), pages 601 - 606, ISSN: 0003-987X *
OFFNER, HALINA: "Neuroimmunoprotective effects of estrogen and derivatives in experimental autoimmune encephalomyelitis: Therapeutic implications for multiple sclerosis", JOURNAL OF NEUROSCIENCE RESEARCH ( 2004 ), 78(5), 603-624 CODEN: JNREDK; ISSN: 0360-4012, 28 October 2004 (2004-10-28), XP002605593 *
RATKAY L G ET AL: "Evaluation of a model for post-partum arthritis and the role of oestrogen in prevention of MRL-lpr associated rheumatic conditions", CLINICAL AND EXPERIMENTAL IMMUNOLOGY, vol. 98, no. 1, 1994, pages 52 - 59, XP002606112, ISSN: 0009-9104 *
SAMANTHA S SOLDAN ET AL: "Immune modulation in multiple sclerosis patients treated with the pregnancy hormone estriol", JOURNAL OF IMMUNOLOGY, AMERICAN ASSOCIATION OF IMMUNOLOGISTS, US, vol. 171, no. 11, 1 December 2003 (2003-12-01), pages 6267 - 6268, XP008126547, ISSN: 0022-1767 *

Also Published As

Publication number Publication date
WO2007038435A2 (fr) 2007-04-05
JP2009510070A (ja) 2009-03-12
AU2006294826A1 (en) 2007-04-05
WO2007038435A3 (fr) 2007-06-28
EP1928468A2 (fr) 2008-06-11
CA2623905A1 (fr) 2007-04-05

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Ipc: A61K 31/565 20060101ALI20101022BHEP

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Ipc: A61K 31/566 20060101ALI20101022BHEP

Ipc: A61K 31/568 20060101ALI20101022BHEP

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