EP1924698A4 - Thérapie génique oculaire utilisant la transfection médiée par avalanche - Google Patents
Thérapie génique oculaire utilisant la transfection médiée par avalancheInfo
- Publication number
- EP1924698A4 EP1924698A4 EP06801803A EP06801803A EP1924698A4 EP 1924698 A4 EP1924698 A4 EP 1924698A4 EP 06801803 A EP06801803 A EP 06801803A EP 06801803 A EP06801803 A EP 06801803A EP 1924698 A4 EP1924698 A4 EP 1924698A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- avalanche
- gene therapy
- mediated transfection
- ocular gene
- ocular
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000001415 gene therapy Methods 0.000 title 1
- 230000001404 mediated effect Effects 0.000 title 1
- 238000001890 transfection Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US70848605P | 2005-08-15 | 2005-08-15 | |
US36098406A | 2006-02-22 | 2006-02-22 | |
PCT/US2006/032249 WO2007022403A2 (fr) | 2005-08-15 | 2006-08-15 | Therapie genique oculaire utilisant la transfection mediee par avalanche |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1924698A2 EP1924698A2 (fr) | 2008-05-28 |
EP1924698A4 true EP1924698A4 (fr) | 2010-12-15 |
Family
ID=37758427
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP06801803A Withdrawn EP1924698A4 (fr) | 2005-08-15 | 2006-08-15 | Thérapie génique oculaire utilisant la transfection médiée par avalanche |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1924698A4 (fr) |
JP (1) | JP2009507780A (fr) |
AU (1) | AU2006279395A1 (fr) |
CA (1) | CA2620294A1 (fr) |
WO (1) | WO2007022403A2 (fr) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8101169B2 (en) * | 2005-02-23 | 2012-01-24 | The Board Of Trustees Of The Leland Stanford Junior University | Ocular gene therapy using avalanche-mediated transfection |
WO2009062149A1 (fr) * | 2007-11-08 | 2009-05-14 | Creighton University | Procédés pour conserver les neurones de l'oreille interne |
WO2012086702A1 (fr) * | 2010-12-24 | 2012-06-28 | タカラバイオ株式会社 | Technique d'introduction de gènes |
EP2670477B1 (fr) * | 2011-02-01 | 2015-11-25 | Moe Medical Devices LLC | Traitement de la peau assisté par plasma |
WO2013040542A1 (fr) * | 2011-09-17 | 2013-03-21 | Moe Medical Devices Llc | Systèmes, procédés et programmes lisibles par machine pour le traitement des onychomycoses assisté par champ électrique et / ou par plasma |
US9351790B2 (en) | 2011-09-17 | 2016-05-31 | M.O.E. Medical Devices Llc | Electrode geometries and method for applying electric field treatment to parts of the body |
JP6317927B2 (ja) | 2012-01-09 | 2018-04-25 | ムー・メディカル・デバイスズ・エルエルシーMoe Medical Devices Llc | プラズマ補助皮膚処置 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6267954B1 (en) * | 1999-11-24 | 2001-07-31 | Universite De Paris V Rene-Descartes | Intraocular transplantation of encapsulated cells |
US20050148530A1 (en) * | 2002-02-20 | 2005-07-07 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA) |
-
2006
- 2006-08-15 AU AU2006279395A patent/AU2006279395A1/en not_active Abandoned
- 2006-08-15 WO PCT/US2006/032249 patent/WO2007022403A2/fr active Application Filing
- 2006-08-15 JP JP2008527156A patent/JP2009507780A/ja active Pending
- 2006-08-15 CA CA002620294A patent/CA2620294A1/fr not_active Abandoned
- 2006-08-15 EP EP06801803A patent/EP1924698A4/fr not_active Withdrawn
Non-Patent Citations (6)
Title |
---|
BORRAS T: "RECENT DEVELOPMENTS IN OCULAR GENE THERAPY", EXPERIMENTAL EYE RESEARCH, ACADEMIC PRESS LTD, LONDON LNKD- DOI:10.1016/S0014-4835(03)00030-7, vol. 76, no. 6, 1 June 2003 (2003-06-01), pages 643 - 652, XP001155551, ISSN: 0014-4835 * |
CHALBERG T W ET AL: "Novel physical methods for nonviral DNA transfection of RPE", IOVS, vol. 46, no. Suppl. S, 2005, & ANNUAL MEETING OF THE ASSOCIATION-FOR-RESEARCH-IN-VISION-AND-OPHTHALM OLOGY; FT LAUDERDALE, FL, USA; MAY 01 -05, 2005, pages 4690, XP009130924, ISSN: 0146-0404 * |
CHALBERG THOMAS W ET AL: "phiC31 integrase confers genomic integration and long-term transgene expression in rat retina.", INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE JUN 2005 LNKD- PUBMED:15914635, vol. 46, no. 6, June 2005 (2005-06-01), pages 2140 - 2146, XP002606111, ISSN: 0146-0404 * |
MILLER JASON M ET AL: "Precision and safety of the pulsed electron avalanche knife in vitreoretinal surgery.", ARCHIVES OF OPHTHALMOLOGY, vol. 121, no. 6, June 2003 (2003-06-01), pages 871 - 877, XP009130925, ISSN: 0003-9950 * |
SEMKOVA IRINA ET AL: "Autologous transplantation of genetically modified iris pigment epithelial cells: a promising concept for the treatment of age-related macular degeneration and other disorders of the eye.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 1 OCT 2002 LNKD- PUBMED:12239351, vol. 99, no. 20, 1 October 2002 (2002-10-01), pages 13090 - 13095, XP002606109, ISSN: 0027-8424 * |
TAMAI MAKOTO: "Progress in pathogenesis and therapeutic research in retinitis pigmentosa and age-related macular degeneration", NIPPON GANKA GAKKAI ZASSHI, vol. 108, no. 12, December 2004 (2004-12-01), pages 750 - 769, XP009140228, ISSN: 0029-0203 * |
Also Published As
Publication number | Publication date |
---|---|
WO2007022403A2 (fr) | 2007-02-22 |
JP2009507780A (ja) | 2009-02-26 |
CA2620294A1 (fr) | 2007-02-22 |
WO2007022403A3 (fr) | 2010-04-22 |
AU2006279395A1 (en) | 2007-02-22 |
EP1924698A2 (fr) | 2008-05-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20080327 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR |
|
AX | Request for extension of the european patent |
Extension state: AL BA HR MK RS |
|
R17D | Deferred search report published (corrected) |
Effective date: 20100422 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: C12N 15/87 20060101ALI20101102BHEP Ipc: C12M 1/42 20060101ALI20101102BHEP Ipc: C12N 15/64 20060101AFI20101102BHEP |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20101111 |
|
DAX | Request for extension of the european patent (deleted) | ||
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20110611 |