EP1906976A4 - Therapeutische polymere und anwendungsverfahren - Google Patents
Therapeutische polymere und anwendungsverfahrenInfo
- Publication number
- EP1906976A4 EP1906976A4 EP06760640A EP06760640A EP1906976A4 EP 1906976 A4 EP1906976 A4 EP 1906976A4 EP 06760640 A EP06760640 A EP 06760640A EP 06760640 A EP06760640 A EP 06760640A EP 1906976 A4 EP1906976 A4 EP 1906976A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- methods
- therapeutic polymers
- therapeutic
- polymers
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/0008—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
- A61K48/0025—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition wherein the non-active part clearly interacts with the delivered nucleic acid
- A61K48/0041—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition wherein the non-active part clearly interacts with the delivered nucleic acid the non-active part being polymeric
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/593—Polyesters, e.g. PLGA or polylactide-co-glycolide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/595—Polyamides, e.g. nylon
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G71/00—Macromolecular compounds obtained by reactions forming a ureide or urethane link, otherwise, than from isocyanate radicals in the main chain of the macromolecule
- C08G71/04—Polyurethanes
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L77/00—Compositions of polyamides obtained by reactions forming a carboxylic amide link in the main chain; Compositions of derivatives of such polymers
- C08L77/12—Polyester-amides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Polyamides (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US68757005P | 2005-06-03 | 2005-06-03 | |
US75917906P | 2006-01-13 | 2006-01-13 | |
PCT/US2006/021395 WO2006132950A2 (en) | 2005-06-03 | 2006-06-02 | Therapeutic polymers and methods of use |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1906976A2 EP1906976A2 (de) | 2008-04-09 |
EP1906976A4 true EP1906976A4 (de) | 2011-11-09 |
Family
ID=37498935
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP06760640A Withdrawn EP1906976A4 (de) | 2005-06-03 | 2006-06-02 | Therapeutische polymere und anwendungsverfahren |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1906976A4 (de) |
JP (1) | JP2008542393A (de) |
AU (1) | AU2006255262A1 (de) |
CA (1) | CA2610745A1 (de) |
WO (1) | WO2006132950A2 (de) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060177416A1 (en) | 2003-10-14 | 2006-08-10 | Medivas, Llc | Polymer particle delivery compositions and methods of use |
US7273469B1 (en) | 2003-12-31 | 2007-09-25 | Advanced Cardiovascular Systems, Inc. | Modified needle catheter for directional orientation delivery |
WO2007035938A2 (en) | 2005-09-22 | 2007-03-29 | Medivas, Llc | BIS-(α-AMINO)-DIOL-DIESTER-CONTAINING POLY(ESTER AMIDE) AND POLY(ESTER URETHANE) COMPOSITIONS AND METHODS OF USE |
US8445627B2 (en) * | 2006-03-24 | 2013-05-21 | Medivas, Llc | Alkylene-dicarboxylate-containing biodegradable poly(ester-amides) and methods of use |
JP5196498B2 (ja) * | 2006-05-09 | 2013-05-15 | メディバス エルエルシー | 生分解性水溶性ポリマー |
US20080200377A1 (en) * | 2007-02-16 | 2008-08-21 | Trollsas Mikael O | Polymer particles |
CA2714156A1 (en) * | 2007-12-06 | 2009-06-11 | Medivas, Llc | Oligo-ethylene glycol-based polymer compositions and methods of use |
CN103619910B (zh) | 2011-06-23 | 2016-08-31 | 帝斯曼知识产权资产管理有限公司 | 用于药物递送的新颖的聚酯酰胺共聚物 |
US9873765B2 (en) | 2011-06-23 | 2018-01-23 | Dsm Ip Assets, B.V. | Biodegradable polyesteramide copolymers for drug delivery |
JP6720447B2 (ja) | 2014-12-18 | 2020-07-08 | ディーエスエム アイピー アセッツ ビー.ブイ.Dsm Ip Assets B.V. | 酸感受性薬剤の送達のための薬剤送達系 |
CA2988679A1 (en) * | 2015-06-23 | 2016-12-29 | Phagelux (Canada), Inc. | Composition comprising amino acid polymers and a bioactive agent and method of preparing thereof |
CN110804175B (zh) * | 2019-11-08 | 2021-05-14 | 中国科学院理化技术研究所 | 一种交替结构抗菌聚氨基酸衍生物或共聚物及其制备方法 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020015720A1 (en) * | 2000-01-11 | 2002-02-07 | Ramaz Katsarava | Polymer blends as biodegradable matrices for preparing biocomposites |
US20020071822A1 (en) * | 2000-07-27 | 2002-06-13 | Uhrich Kathryn E. | Therapeutic polyesters and polyamides |
EP1945682A2 (de) * | 2005-10-21 | 2008-07-23 | Medivas, LLC | Poly(esterharnstoff)-polymere und verwendungsverfahren |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1250143A2 (de) * | 2000-01-11 | 2002-10-23 | Intralytix Inc. | Reduzierung von bakterielle kolonization mit bakteriophagen als wirkstoff |
US6503538B1 (en) * | 2000-08-30 | 2003-01-07 | Cornell Research Foundation, Inc. | Elastomeric functional biodegradable copolyester amides and copolyester urethanes |
CN1684641A (zh) * | 2002-09-26 | 2005-10-19 | 血管内装置有限公司 | 用于递送丝裂霉素通过洗脱生物相容可移植医疗器件的装置和方法 |
-
2006
- 2006-06-02 WO PCT/US2006/021395 patent/WO2006132950A2/en active Application Filing
- 2006-06-02 EP EP06760640A patent/EP1906976A4/de not_active Withdrawn
- 2006-06-02 JP JP2008514885A patent/JP2008542393A/ja active Pending
- 2006-06-02 AU AU2006255262A patent/AU2006255262A1/en not_active Abandoned
- 2006-06-02 CA CA002610745A patent/CA2610745A1/en not_active Abandoned
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020015720A1 (en) * | 2000-01-11 | 2002-02-07 | Ramaz Katsarava | Polymer blends as biodegradable matrices for preparing biocomposites |
US20020071822A1 (en) * | 2000-07-27 | 2002-06-13 | Uhrich Kathryn E. | Therapeutic polyesters and polyamides |
EP1945682A2 (de) * | 2005-10-21 | 2008-07-23 | Medivas, LLC | Poly(esterharnstoff)-polymere und verwendungsverfahren |
Non-Patent Citations (3)
Title |
---|
MAURO A.M CARAI ET AL: "Central effects of 1,4-butanediol are mediated by GABAB receptors via its conversion into [gamma]-hydroxybutyric acid", EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 441, no. 3, 1 April 2002 (2002-04-01), pages 157 - 163, XP055008078, ISSN: 0014-2999, DOI: 10.1016/S0014-2999(02)01502-9 * |
SCHMELTZER R C ET AL: "Synthesis and cytotoxicity of salicylate-based poly(anhydride esters)", BIOMACROMOLECULES, ACS, WASHINGTON, DC, US, vol. 6, no. 1, 1 January 2005 (2005-01-01), pages 359 - 367, XP002482507, ISSN: 1525-7797, [retrieved on 20041126], DOI: 10.1021/BM049544+ * |
WOO G L Y ET AL: "Synthesis and characterization of a novel biodegradable antimicrobial polymer", BIOMATERIALS, ELSEVIER SCIENCE PUBLISHERS BV., BARKING, GB, vol. 21, no. 12, 1 June 2000 (2000-06-01), pages 1235 - 1246, XP004195834, ISSN: 0142-9612, DOI: 10.1016/S0142-9612(00)00003-X * |
Also Published As
Publication number | Publication date |
---|---|
JP2008542393A (ja) | 2008-11-27 |
EP1906976A2 (de) | 2008-04-09 |
CA2610745A1 (en) | 2006-12-14 |
WO2006132950A2 (en) | 2006-12-14 |
AU2006255262A1 (en) | 2006-12-14 |
WO2006132950A3 (en) | 2007-06-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20071228 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR |
|
DAX | Request for extension of the european patent (deleted) | ||
A4 | Supplementary search report drawn up and despatched |
Effective date: 20111011 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: C08L 75/02 20060101ALI20111005BHEP Ipc: A61K 31/785 20060101ALI20111005BHEP Ipc: C08L 77/00 20060101AFI20111005BHEP Ipc: A61K 9/16 20060101ALI20111005BHEP Ipc: A61K 9/51 20060101ALI20111005BHEP Ipc: C08G 18/10 20060101ALI20111005BHEP Ipc: C12N 15/88 20060101ALI20111005BHEP Ipc: A61K 47/34 20060101ALI20111005BHEP Ipc: C08G 69/44 20060101ALI20111005BHEP Ipc: C08L 77/12 20060101ALI20111005BHEP Ipc: A61K 47/48 20060101ALI20111005BHEP Ipc: A61K 48/00 20060101ALI20111005BHEP Ipc: A61K 9/50 20060101ALI20111005BHEP Ipc: C07K 16/28 20060101ALI20111005BHEP Ipc: A61K 9/107 20060101ALI20111005BHEP Ipc: A61F 2/00 20060101ALI20111005BHEP Ipc: C08L 75/06 20060101ALI20111005BHEP Ipc: C08L 75/04 20060101ALI20111005BHEP Ipc: A61L 31/00 20060101ALI20111005BHEP |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20120508 |