EP1904653A4 - MICROFLUIDIC PROCESSES AND DEVICES FOR PREPARING AND ANALYZING SAMPLES - Google Patents

MICROFLUIDIC PROCESSES AND DEVICES FOR PREPARING AND ANALYZING SAMPLES

Info

Publication number
EP1904653A4
EP1904653A4 EP06787065A EP06787065A EP1904653A4 EP 1904653 A4 EP1904653 A4 EP 1904653A4 EP 06787065 A EP06787065 A EP 06787065A EP 06787065 A EP06787065 A EP 06787065A EP 1904653 A4 EP1904653 A4 EP 1904653A4
Authority
EP
European Patent Office
Prior art keywords
apparatuses
analysis
sample preparation
microfluidic methods
microfluidic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP06787065A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP1904653A2 (en
Inventor
Gregory R Yantz
Jonathan W Larson
Rudolf Gilmanshin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Genomics Inc
Original Assignee
US Genomics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by US Genomics Inc filed Critical US Genomics Inc
Publication of EP1904653A2 publication Critical patent/EP1904653A2/en
Publication of EP1904653A4 publication Critical patent/EP1904653A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y10/00—Nanotechnology for information processing, storage or transmission, e.g. quantum computing or single electron logic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502776—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for focusing or laminating flows
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0636—Focussing flows, e.g. to laminate flows
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0663—Stretching or orienting elongated molecules or particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Nanotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Fluid Mechanics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mathematical Physics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Theoretical Computer Science (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
EP06787065A 2005-07-18 2006-07-13 MICROFLUIDIC PROCESSES AND DEVICES FOR PREPARING AND ANALYZING SAMPLES Withdrawn EP1904653A4 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US70049005P 2005-07-18 2005-07-18
US70048005P 2005-07-18 2005-07-18
US70068905P 2005-07-18 2005-07-18
PCT/US2006/027111 WO2007011622A2 (en) 2005-07-18 2006-07-13 Microfluidic methods and apparatuses for sample preparation and analysis

Publications (2)

Publication Number Publication Date
EP1904653A2 EP1904653A2 (en) 2008-04-02
EP1904653A4 true EP1904653A4 (en) 2010-04-14

Family

ID=37669351

Family Applications (1)

Application Number Title Priority Date Filing Date
EP06787065A Withdrawn EP1904653A4 (en) 2005-07-18 2006-07-13 MICROFLUIDIC PROCESSES AND DEVICES FOR PREPARING AND ANALYZING SAMPLES

Country Status (3)

Country Link
EP (1) EP1904653A4 (enExample)
JP (1) JP2009501938A (enExample)
WO (1) WO2007011622A2 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2580589C (en) * 2006-12-19 2016-08-09 Fio Corporation Microfluidic detection system
US20090053732A1 (en) * 2007-07-16 2009-02-26 Ophir Vermesh Microfluidic devices, methods and systems for detecting target molecules
US8551763B2 (en) 2007-10-12 2013-10-08 Fio Corporation Flow focusing method and system for forming concentrated volumes of microbeads, and microbeads formed further thereto
CN102132330B (zh) 2008-06-25 2015-07-22 Fio公司 生物威胁警报系统
US9459200B2 (en) 2008-08-29 2016-10-04 Fio Corporation Single-use handheld diagnostic test device, and an associated system and method for testing biological and environmental test samples
CN104374932A (zh) 2009-01-13 2015-02-25 Fio公司 与电子设备和快速诊断测试中的测试盒结合使用的手持诊断测试设备
US8202486B2 (en) * 2009-08-12 2012-06-19 Caliper Life Sciences, Inc. Pinching channels for fractionation of fragmented samples
US9139426B2 (en) 2010-09-21 2015-09-22 The University Of North Carolina At Chapel Hill Methods, systems and devices for forming nanochannels
WO2013039778A2 (en) 2011-09-12 2013-03-21 The University Of North Carolina At Chapel Hill Devices with a fluid transport nanochannel intersected by a fluid sensing nanochannel and related methods
EP2812708B1 (en) * 2012-02-10 2019-09-04 The University of North Carolina At Chapel Hill Method of analysing an analyte with fluidic nanofunnels
KR20150132125A (ko) 2013-02-28 2015-11-25 더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 거대분자의 통제된 포획, 고정, 및 전달을 위한 통합된 부품을 가진 나노유체 장치 및 관련 분석 방법
NZ711033A (en) 2013-03-13 2020-03-27 Univ North Carolina Chapel Hill Nanofluidic devices for the rapid mapping of whole genomes and related systems and methods of analysis
WO2016182811A1 (en) 2015-05-11 2016-11-17 The University Of North Carolina At Chapel Hill Fluidic devices with nanoscale manifolds for molecular transport, related systems and methods of analysis
EP3645167A4 (en) 2017-06-28 2021-02-24 Bio-rad Laboratories, Inc. DROPLET DETECTION SYSTEM AND METHOD
US11045805B2 (en) 2017-11-01 2021-06-29 Bio-Rad Laboratories, Inc. Microfluidic system and method for arranging objects
US10898895B2 (en) 2018-09-13 2021-01-26 Talis Biomedical Corporation Vented converging capillary biological sample port and reservoir
CN113498362B (zh) 2019-02-27 2023-01-20 京瓷株式会社 粒子分离测量设备以及粒子分离测量装置

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003000416A2 (en) * 2001-06-20 2003-01-03 Teragenics, Inc. Microfluidic system including a virtual wall fluid interface port for interfacing fluids with the microfluidic system
US6506609B1 (en) * 1999-05-17 2003-01-14 Caliper Technologies Corp. Focusing of microparticles in microfluidic systems
US20030159999A1 (en) * 2002-02-04 2003-08-28 John Oakey Laminar Flow-Based Separations of Colloidal and Cellular Particles
EP1380337A2 (en) * 2002-07-12 2004-01-14 Tosoh Corporation Fine channel device and a chemically operating method for fluid using the device
US6770182B1 (en) * 2000-11-14 2004-08-03 Sandia National Laboratories Method for producing a thin sample band in a microchannel device
US20050112606A1 (en) * 2003-04-10 2005-05-26 Martin Fuchs Advanced microfluidics

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4793705A (en) * 1987-10-07 1988-12-27 The United States Of America As Represented By The United States Department Of Energy Single molecule tracking
US5274240A (en) * 1990-01-12 1993-12-28 The Regents Of The University Of California Capillary array confocal fluorescence scanner and method
JP3123249B2 (ja) * 1991-09-10 2001-01-09 株式会社日立製作所 Ｄｎａ分子の長さ計測方法および計測装置
CA2155186A1 (en) * 1993-02-01 1994-08-18 Kevin M. Ulmer Methods and apparatus for dna sequencing
ATE273381T1 (de) * 1997-02-12 2004-08-15 Eugene Y Chan Verfahren zur analyse von polymeren
US6790671B1 (en) * 1998-08-13 2004-09-14 Princeton University Optically characterizing polymers
US6818395B1 (en) * 1999-06-28 2004-11-16 California Institute Of Technology Methods and apparatus for analyzing polynucleotide sequences
AU2002351187A1 (en) * 2001-11-30 2003-06-17 Fluidigm Corporation Microfluidic device and methods of using same

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6506609B1 (en) * 1999-05-17 2003-01-14 Caliper Technologies Corp. Focusing of microparticles in microfluidic systems
US6770182B1 (en) * 2000-11-14 2004-08-03 Sandia National Laboratories Method for producing a thin sample band in a microchannel device
WO2003000416A2 (en) * 2001-06-20 2003-01-03 Teragenics, Inc. Microfluidic system including a virtual wall fluid interface port for interfacing fluids with the microfluidic system
US20030159999A1 (en) * 2002-02-04 2003-08-28 John Oakey Laminar Flow-Based Separations of Colloidal and Cellular Particles
EP1380337A2 (en) * 2002-07-12 2004-01-14 Tosoh Corporation Fine channel device and a chemically operating method for fluid using the device
US20050112606A1 (en) * 2003-04-10 2005-05-26 Martin Fuchs Advanced microfluidics

Also Published As

Publication number Publication date
WO2007011622A2 (en) 2007-01-25
JP2009501938A (ja) 2009-01-22
WO2007011622A3 (en) 2007-05-24
EP1904653A2 (en) 2008-04-02

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Designated state(s): DE FR GB

RIN1 Information on inventor provided before grant (corrected)

Inventor name: LARSON, JONATHAN, W.

Inventor name: GILMANSHIN, RUDOLF

Inventor name: YANTZ, GREGORY, R.

A4 Supplementary search report drawn up and despatched

Effective date: 20100316

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