EP1883697A4 - Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors - Google Patents

Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors

Info

Publication number
EP1883697A4
EP1883697A4 EP06751574A EP06751574A EP1883697A4 EP 1883697 A4 EP1883697 A4 EP 1883697A4 EP 06751574 A EP06751574 A EP 06751574A EP 06751574 A EP06751574 A EP 06751574A EP 1883697 A4 EP1883697 A4 EP 1883697A4
Authority
EP
European Patent Office
Prior art keywords
monatin
stereoisomers
polypeptides
precursors
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP06751574A
Other languages
German (de)
French (fr)
Other versions
EP1883697A2 (en
Inventor
Brian J Brazeau
Ellen Burke
Souza Mervyn De
Steven J Gort
Paula M Hicks
Sherry R Kollman
Peter Luginbuhl
Sara C Mcfarlan
Toby Richardson
Fernando A Sanchez-Riera
Christopher Solheid
David Weiner
Lishan Zhao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cargill Inc
Original Assignee
Cargill Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cargill Inc filed Critical Cargill Inc
Priority to EP16001105.2A priority Critical patent/EP3168299A3/en
Priority to EP11000670.7A priority patent/EP2361976B1/en
Publication of EP1883697A2 publication Critical patent/EP1883697A2/en
Publication of EP1883697A4 publication Critical patent/EP1883697A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
EP06751574A 2005-04-26 2006-04-26 Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors Withdrawn EP1883697A4 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP16001105.2A EP3168299A3 (en) 2005-04-26 2006-04-26 Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
EP11000670.7A EP2361976B1 (en) 2005-04-26 2006-04-26 Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67493205P 2005-04-26 2005-04-26
PCT/US2006/015930 WO2007133184A2 (en) 2005-04-26 2006-04-26 Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors

Related Child Applications (2)

Application Number Title Priority Date Filing Date
EP16001105.2A Division EP3168299A3 (en) 2005-04-26 2006-04-26 Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
EP11000670.7A Division EP2361976B1 (en) 2005-04-26 2006-04-26 Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors

Publications (2)

Publication Number Publication Date
EP1883697A2 EP1883697A2 (en) 2008-02-06
EP1883697A4 true EP1883697A4 (en) 2010-05-05

Family

ID=38694337

Family Applications (3)

Application Number Title Priority Date Filing Date
EP16001105.2A Withdrawn EP3168299A3 (en) 2005-04-26 2006-04-26 Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
EP11000670.7A Not-in-force EP2361976B1 (en) 2005-04-26 2006-04-26 Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
EP06751574A Withdrawn EP1883697A4 (en) 2005-04-26 2006-04-26 Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors

Family Applications Before (2)

Application Number Title Priority Date Filing Date
EP16001105.2A Withdrawn EP3168299A3 (en) 2005-04-26 2006-04-26 Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
EP11000670.7A Not-in-force EP2361976B1 (en) 2005-04-26 2006-04-26 Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors

Country Status (8)

Country Link
EP (3) EP3168299A3 (en)
JP (1) JP5336182B2 (en)
CN (1) CN101365787B (en)
AU (1) AU2006341528A1 (en)
BR (1) BRPI0609876A2 (en)
CA (1) CA2638896C (en)
ES (1) ES2587572T3 (en)
WO (1) WO2007133184A2 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7572607B2 (en) 2002-04-23 2009-08-11 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of monatin and its precursors
US8372989B2 (en) 2002-04-23 2013-02-12 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of monatin and its precursors
US7582455B2 (en) * 2005-04-26 2009-09-01 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
EP2322643B1 (en) 2006-03-07 2014-07-09 Cargill, Incorporated Aldolases, nucleic acids encoding them and methods for making and using them
EP2038405A4 (en) 2006-05-24 2009-10-21 Cargill Inc Methods and systems for increasing production of equilibrium reactions
US8003361B2 (en) 2007-10-01 2011-08-23 Cargill Incorporated Production of monatin enantiomers
US8367847B2 (en) 2007-10-01 2013-02-05 Cargill, Incorporated Production of monatin enantiomers
US8076107B2 (en) * 2007-10-01 2011-12-13 Cargill, Incorporated Production of monatin stereoisomers
EP2479272A4 (en) 2010-10-14 2013-11-20 Ajinomoto Kk Method for producing monatin
US8771997B2 (en) 2011-04-20 2014-07-08 Ajinomoto Co., Inc. Method for producing monatin using an L-amino acid aminotransferase
WO2012147674A1 (en) * 2011-04-25 2012-11-01 味の素株式会社 Process for producing monatin
JP6284474B2 (en) 2011-06-24 2018-02-28 メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． Immobilized transaminase and methods for making and using immobilized transaminase
WO2013073679A1 (en) * 2011-11-17 2013-05-23 味の素株式会社 Method for producing (2r,4r)-monatin polyvalent metal salt crystals
CN105073983B (en) 2013-02-28 2018-09-18 默沙东公司 Immobilization transaminase and preparation and the method for using immobilization transaminase
EP2970927A4 (en) 2013-03-15 2016-10-12 Merck Sharp & Dohme Immobilized ketoreductases and process for making and using immobilized ketoreductase

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003091396A2 (en) * 2002-04-23 2003-11-06 Cargill, Incorporated Polypeptides and biosynthetic pathways
JP2004222657A (en) * 2003-01-24 2004-08-12 Ajinomoto Co Inc Method of producing 2r-monatin
WO2005001105A1 (en) * 2003-06-26 2005-01-06 Ajinomoto Co., Inc. Method for producing monatin
WO2005016022A1 (en) * 2003-08-14 2005-02-24 Cargill, Incorporated Chewing gum compositions comprising monatin and methods of making same
WO2005020721A1 (en) * 2003-08-25 2005-03-10 Cargill, Incorporated Beverage compositions comprising monatin and methods of making same

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69101791T2 (en) 1990-01-19 1994-08-11 Technology Finance Corp Process for the preparation of 3- (1-amino-1,3-dicarboxy-3-hydroxy-but-4-yl) indole.
US5728555A (en) 1996-09-30 1998-03-17 Monsanto Company Preparation of d-amino acids by direct fermentative means
EP1637160A3 (en) 1999-05-07 2006-05-03 Genentech, Inc. Treatment of autoimmune diseases with antagonists which bind to B cell surface markers
JP2002060382A (en) * 2000-08-22 2002-02-26 Ajinomoto Co Inc Stereoisomer of monatin and use thereof, method for producing monatins and intermediate therefor
JP2003171365A (en) * 2001-11-30 2003-06-20 Ajinomoto Co Inc Method for producing monatin compound, its production intermediate, and new intermediate
RU2280078C2 (en) * 2001-12-27 2006-07-20 Адзиномото Ко., Инк. Methods for production of glutamate (variants) and monatin
JP2003292484A (en) * 2002-04-01 2003-10-15 Ajinomoto Co Inc METHOD FOR PRODUCING gamma-HYDROXYAMINO ACID DERIVATIVE AND MONATINS
US7572607B2 (en) 2002-04-23 2009-08-11 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of monatin and its precursors
WO2005042756A2 (en) * 2003-10-21 2005-05-12 Cargill, Incorporated Production of monatin and monatin precursors
US7582455B2 (en) * 2005-04-26 2009-09-01 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003091396A2 (en) * 2002-04-23 2003-11-06 Cargill, Incorporated Polypeptides and biosynthetic pathways
JP2004222657A (en) * 2003-01-24 2004-08-12 Ajinomoto Co Inc Method of producing 2r-monatin
WO2005001105A1 (en) * 2003-06-26 2005-01-06 Ajinomoto Co., Inc. Method for producing monatin
US20060154343A1 (en) * 2003-06-26 2006-07-13 Ajinomoto Co., Inc. Method for producing monatin
WO2005016022A1 (en) * 2003-08-14 2005-02-24 Cargill, Incorporated Chewing gum compositions comprising monatin and methods of making same
WO2005020721A1 (en) * 2003-08-25 2005-03-10 Cargill, Incorporated Beverage compositions comprising monatin and methods of making same

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
"EC 2.6.1.27 - tryptophan transaminase", BRENDA THE COMPREHENSIVE ENZYME INFORMATION SYSTEM, 2009, XP002526345, Retrieved from the Internet <URL:http://www.brenda-enzymes.org/php/result_flat.php4?ecno=2.6.1.27> [retrieved on 20090429] *
DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 12 August 2004 (2004-08-12), SUGIYAMA, MASAKAZU ET AL: "2R-monatin manufacture by enzymic resolution", XP002526346, retrieved from STN Database accession no. 141:172983 *
KOSHIBA T ET AL: "L- AND D-TRYPTOPHAN AMINOTRANSFERASES FROM MAIZE COLEOPTILES", JOURNAL OF PLANT RESEARCH, TOKYO, JP, vol. 106, no. 1081, 1 January 1993 (1993-01-01), pages 25 - 29, XP008020474, ISSN: 0918-9440 *

Also Published As

Publication number Publication date
AU2006341528A8 (en) 2009-01-08
CA2638896C (en) 2015-01-27
EP3168299A3 (en) 2017-07-05
BRPI0609876A2 (en) 2010-05-11
EP2361976A2 (en) 2011-08-31
WO2007133184A3 (en) 2008-08-28
EP1883697A2 (en) 2008-02-06
WO2007133184A2 (en) 2007-11-22
CN101365787A (en) 2009-02-11
CA2638896A1 (en) 2007-11-22
CN101365787B (en) 2014-03-05
AU2006341528A1 (en) 2007-12-06
JP2008538932A (en) 2008-11-13
EP3168299A2 (en) 2017-05-17
JP5336182B2 (en) 2013-11-06
EP2361976B1 (en) 2016-05-25
ES2587572T3 (en) 2016-10-25
EP2361976A3 (en) 2012-08-01

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: CARGILL, INCORPORATED

RIC1 Information provided on ipc code assigned before grant

Ipc: H04L 9/00 20060101AFI20080121BHEP

RIN1 Information on inventor provided before grant (corrected)

Inventor name: ZHAO, LISHAN

Inventor name: WEINER, DAVID

Inventor name: SOLHEID, CHRISTOPHER

Inventor name: SANCHEZ-RIERA, FERNANDO A.

Inventor name: RICHARDSON, TOBY

Inventor name: MCFARLAN, SARA, C.

Inventor name: LUGINBUHL,PETER

Inventor name: KOLLMAN, SHERRY R.

Inventor name: HICKS, PAULA M.

Inventor name: GORT, STEVEN J.

Inventor name: DE SOUZA, MERVYN

Inventor name: BURKE, ELLEN

Inventor name: BRAZEAU, BRIAN J.

RIN1 Information on inventor provided before grant (corrected)

Inventor name: ZHAO, LISHAN

Inventor name: WEINER, DAVID

Inventor name: SOLHEID, CHRISTOPHER

Inventor name: SANCHEZ-RIERA, FERNANDO A.

Inventor name: RICHARDSON, TOBY

Inventor name: MCFARLAN, SARA, C.

Inventor name: LUGINBUHL,PETER

Inventor name: KOLLMAN, SHERRY R.

Inventor name: HICKS, PAULA M.

Inventor name: GORT, STEVEN J.

Inventor name: DE SOUZA, MERVYN

Inventor name: BURKE, ELLEN

Inventor name: BRAZEAU, BRIAN J.

RIC1 Information provided on ipc code assigned before grant

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Ipc: C12P 13/22 20060101ALI20100326BHEP

Ipc: C12N 9/10 20060101AFI20080904BHEP

RIN1 Information on inventor provided before grant (corrected)

Inventor name: ZHAO, LISHAN

Inventor name: WEINER, DAVID

Inventor name: SOLHEID, CHRISTOPHER

Inventor name: SANCHEZ-RIERA, FERNANDO A.

Inventor name: RICHARDSON, TOBY

Inventor name: MCFARLAN, SARA, C.

Inventor name: LUGINBUHL, PETER

Inventor name: KOLLMAN, SHERRY R.

Inventor name: HICKS, PAULA M.

Inventor name: GORT, STEVEN J.

Inventor name: DE SOUZA, MERVYN

Inventor name: BURKE, ELLEN

Inventor name: BRAZEAU, BRIAN J.

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