EP1883697A4 - Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors - Google Patents
Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursorsInfo
- Publication number
- EP1883697A4 EP1883697A4 EP06751574A EP06751574A EP1883697A4 EP 1883697 A4 EP1883697 A4 EP 1883697A4 EP 06751574 A EP06751574 A EP 06751574A EP 06751574 A EP06751574 A EP 06751574A EP 1883697 A4 EP1883697 A4 EP 1883697A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- monatin
- stereoisomers
- polypeptides
- precursors
- production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/90—Isomerases (5.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/10—Nitrogen as only ring hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Indole Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP16001105.2A EP3168299A3 (en) | 2005-04-26 | 2006-04-26 | Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors |
EP11000670.7A EP2361976B1 (en) | 2005-04-26 | 2006-04-26 | Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US67493205P | 2005-04-26 | 2005-04-26 | |
PCT/US2006/015930 WO2007133184A2 (en) | 2005-04-26 | 2006-04-26 | Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP11000670.7A Division EP2361976B1 (en) | 2005-04-26 | 2006-04-26 | Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors |
EP16001105.2A Division EP3168299A3 (en) | 2005-04-26 | 2006-04-26 | Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1883697A2 EP1883697A2 (en) | 2008-02-06 |
EP1883697A4 true EP1883697A4 (en) | 2010-05-05 |
Family
ID=38694337
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP11000670.7A Not-in-force EP2361976B1 (en) | 2005-04-26 | 2006-04-26 | Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors |
EP16001105.2A Withdrawn EP3168299A3 (en) | 2005-04-26 | 2006-04-26 | Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors |
EP06751574A Withdrawn EP1883697A4 (en) | 2005-04-26 | 2006-04-26 | Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP11000670.7A Not-in-force EP2361976B1 (en) | 2005-04-26 | 2006-04-26 | Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors |
EP16001105.2A Withdrawn EP3168299A3 (en) | 2005-04-26 | 2006-04-26 | Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors |
Country Status (8)
Country | Link |
---|---|
EP (3) | EP2361976B1 (en) |
JP (1) | JP5336182B2 (en) |
CN (1) | CN101365787B (en) |
AU (1) | AU2006341528A1 (en) |
BR (1) | BRPI0609876A2 (en) |
CA (1) | CA2638896C (en) |
ES (1) | ES2587572T3 (en) |
WO (1) | WO2007133184A2 (en) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7572607B2 (en) | 2002-04-23 | 2009-08-11 | Cargill, Incorporated | Polypeptides and biosynthetic pathways for the production of monatin and its precursors |
US8372989B2 (en) | 2002-04-23 | 2013-02-12 | Cargill, Incorporated | Polypeptides and biosynthetic pathways for the production of monatin and its precursors |
US7582455B2 (en) * | 2005-04-26 | 2009-09-01 | Cargill, Incorporated | Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors |
MX2008011477A (en) | 2006-03-07 | 2008-09-23 | Cargill Inc | Aldolases, nucleic acids encoding them and methods for making and using them. |
CA2653054A1 (en) | 2006-05-24 | 2007-12-06 | Cargill, Incorporated | Methods and systems for increasing production of equilibrium reactions |
US8367847B2 (en) | 2007-10-01 | 2013-02-05 | Cargill, Incorporated | Production of monatin enantiomers |
US8003361B2 (en) | 2007-10-01 | 2011-08-23 | Cargill Incorporated | Production of monatin enantiomers |
US8076107B2 (en) * | 2007-10-01 | 2011-12-13 | Cargill, Incorporated | Production of monatin stereoisomers |
CN102741406A (en) | 2010-10-14 | 2012-10-17 | 味之素株式会社 | Method for producing monatin |
US8771997B2 (en) | 2011-04-20 | 2014-07-08 | Ajinomoto Co., Inc. | Method for producing monatin using an L-amino acid aminotransferase |
WO2012147674A1 (en) * | 2011-04-25 | 2012-11-01 | 味の素株式会社 | Process for producing monatin |
CA2838744C (en) * | 2011-06-24 | 2020-10-13 | Merck Sharp & Dohme Corp. | Immobilized transaminases and process for making and using immobilized transaminase |
WO2013073679A1 (en) * | 2011-11-17 | 2013-05-23 | 味の素株式会社 | Method for producing (2r,4r)-monatin polyvalent metal salt crystals |
CN105073983B (en) | 2013-02-28 | 2018-09-18 | 默沙东公司 | Immobilization transaminase and preparation and the method for using immobilization transaminase |
EP2970927A4 (en) | 2013-03-15 | 2016-10-12 | Merck Sharp & Dohme | Immobilized ketoreductases and process for making and using immobilized ketoreductase |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003091396A2 (en) * | 2002-04-23 | 2003-11-06 | Cargill, Incorporated | Polypeptides and biosynthetic pathways |
JP2004222657A (en) * | 2003-01-24 | 2004-08-12 | Ajinomoto Co Inc | Method of producing 2r-monatin |
WO2005001105A1 (en) * | 2003-06-26 | 2005-01-06 | Ajinomoto Co., Inc. | Method for producing monatin |
WO2005016022A1 (en) * | 2003-08-14 | 2005-02-24 | Cargill, Incorporated | Chewing gum compositions comprising monatin and methods of making same |
WO2005020721A1 (en) * | 2003-08-25 | 2005-03-10 | Cargill, Incorporated | Beverage compositions comprising monatin and methods of making same |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE104961T1 (en) | 1990-01-19 | 1994-05-15 | Technology Finance Corp | PROCESS FOR THE PREPARATION OF 3-(1-AMINO-1,3DICARBOXY-3-HYDROXY-BUT-4-YL)-INDOLE. |
US5728555A (en) | 1996-09-30 | 1998-03-17 | Monsanto Company | Preparation of d-amino acids by direct fermentative means |
CA2372603C (en) | 1999-05-07 | 2015-11-17 | Genentech, Inc. | Treatment of autoimmune diseases with antagonists which bind to b cell surface markers |
JP2002060382A (en) * | 2000-08-22 | 2002-02-26 | Ajinomoto Co Inc | Stereoisomer of monatin and use thereof, method for producing monatins and intermediate therefor |
JP2003171365A (en) * | 2001-11-30 | 2003-06-20 | Ajinomoto Co Inc | Method for producing monatin compound, its production intermediate, and new intermediate |
KR100673283B1 (en) * | 2001-12-27 | 2007-01-24 | 아지노모토 가부시키가이샤 | Process for production of glutamic acid derivatives |
JP2003292484A (en) * | 2002-04-01 | 2003-10-15 | Ajinomoto Co Inc | METHOD FOR PRODUCING gamma-HYDROXYAMINO ACID DERIVATIVE AND MONATINS |
US7572607B2 (en) | 2002-04-23 | 2009-08-11 | Cargill, Incorporated | Polypeptides and biosynthetic pathways for the production of monatin and its precursors |
RU2006117353A (en) * | 2003-10-21 | 2007-12-27 | Карджилл, Инкорпорейтед (Us) | OBTAINING MONATINE AND MONATINE'S PREDATORS |
US7582455B2 (en) * | 2005-04-26 | 2009-09-01 | Cargill, Incorporated | Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors |
-
2006
- 2006-04-26 BR BRPI0609876-2A patent/BRPI0609876A2/en not_active Application Discontinuation
- 2006-04-26 EP EP11000670.7A patent/EP2361976B1/en not_active Not-in-force
- 2006-04-26 JP JP2008515698A patent/JP5336182B2/en not_active Expired - Fee Related
- 2006-04-26 ES ES11000670.7T patent/ES2587572T3/en active Active
- 2006-04-26 CA CA2638896A patent/CA2638896C/en not_active Expired - Fee Related
- 2006-04-26 EP EP16001105.2A patent/EP3168299A3/en not_active Withdrawn
- 2006-04-26 AU AU2006341528A patent/AU2006341528A1/en not_active Abandoned
- 2006-04-26 WO PCT/US2006/015930 patent/WO2007133184A2/en active Application Filing
- 2006-04-26 CN CN200680022628.5A patent/CN101365787B/en not_active Expired - Fee Related
- 2006-04-26 EP EP06751574A patent/EP1883697A4/en not_active Withdrawn
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003091396A2 (en) * | 2002-04-23 | 2003-11-06 | Cargill, Incorporated | Polypeptides and biosynthetic pathways |
JP2004222657A (en) * | 2003-01-24 | 2004-08-12 | Ajinomoto Co Inc | Method of producing 2r-monatin |
WO2005001105A1 (en) * | 2003-06-26 | 2005-01-06 | Ajinomoto Co., Inc. | Method for producing monatin |
US20060154343A1 (en) * | 2003-06-26 | 2006-07-13 | Ajinomoto Co., Inc. | Method for producing monatin |
WO2005016022A1 (en) * | 2003-08-14 | 2005-02-24 | Cargill, Incorporated | Chewing gum compositions comprising monatin and methods of making same |
WO2005020721A1 (en) * | 2003-08-25 | 2005-03-10 | Cargill, Incorporated | Beverage compositions comprising monatin and methods of making same |
Non-Patent Citations (3)
Title |
---|
"EC 2.6.1.27 - tryptophan transaminase", BRENDA THE COMPREHENSIVE ENZYME INFORMATION SYSTEM, 2009, XP002526345, Retrieved from the Internet <URL:http://www.brenda-enzymes.org/php/result_flat.php4?ecno=2.6.1.27> [retrieved on 20090429] * |
DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 12 August 2004 (2004-08-12), SUGIYAMA, MASAKAZU ET AL: "2R-monatin manufacture by enzymic resolution", XP002526346, retrieved from STN Database accession no. 141:172983 * |
KOSHIBA T ET AL: "L- AND D-TRYPTOPHAN AMINOTRANSFERASES FROM MAIZE COLEOPTILES", JOURNAL OF PLANT RESEARCH, TOKYO, JP, vol. 106, no. 1081, 1 January 1993 (1993-01-01), pages 25 - 29, XP008020474, ISSN: 0918-9440 * |
Also Published As
Publication number | Publication date |
---|---|
AU2006341528A8 (en) | 2009-01-08 |
CN101365787A (en) | 2009-02-11 |
EP2361976A2 (en) | 2011-08-31 |
BRPI0609876A2 (en) | 2010-05-11 |
EP1883697A2 (en) | 2008-02-06 |
EP2361976B1 (en) | 2016-05-25 |
CA2638896A1 (en) | 2007-11-22 |
JP5336182B2 (en) | 2013-11-06 |
ES2587572T3 (en) | 2016-10-25 |
EP3168299A3 (en) | 2017-07-05 |
EP3168299A2 (en) | 2017-05-17 |
WO2007133184A3 (en) | 2008-08-28 |
EP2361976A3 (en) | 2012-08-01 |
JP2008538932A (en) | 2008-11-13 |
CN101365787B (en) | 2014-03-05 |
WO2007133184A2 (en) | 2007-11-22 |
CA2638896C (en) | 2015-01-27 |
AU2006341528A1 (en) | 2007-12-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20071115 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR |
|
AX | Request for extension of the european patent |
Extension state: AL BA HR MK YU |
|
RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: CARGILL, INCORPORATED |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: H04L 9/00 20060101AFI20080121BHEP |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: ZHAO, LISHAN Inventor name: WEINER, DAVID Inventor name: SOLHEID, CHRISTOPHER Inventor name: SANCHEZ-RIERA, FERNANDO A. Inventor name: RICHARDSON, TOBY Inventor name: MCFARLAN, SARA, C. Inventor name: LUGINBUHL,PETER Inventor name: KOLLMAN, SHERRY R. Inventor name: HICKS, PAULA M. Inventor name: GORT, STEVEN J. Inventor name: DE SOUZA, MERVYN Inventor name: BURKE, ELLEN Inventor name: BRAZEAU, BRIAN J. |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: ZHAO, LISHAN Inventor name: WEINER, DAVID Inventor name: SOLHEID, CHRISTOPHER Inventor name: SANCHEZ-RIERA, FERNANDO A. Inventor name: RICHARDSON, TOBY Inventor name: MCFARLAN, SARA, C. Inventor name: LUGINBUHL,PETER Inventor name: KOLLMAN, SHERRY R. Inventor name: HICKS, PAULA M. Inventor name: GORT, STEVEN J. Inventor name: DE SOUZA, MERVYN Inventor name: BURKE, ELLEN Inventor name: BRAZEAU, BRIAN J. |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: C12N 9/10 20060101AFI20080529BHEP |
|
DAX | Request for extension of the european patent (deleted) | ||
R17D | Deferred search report published (corrected) |
Effective date: 20080828 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: C12N 1/21 20060101ALI20080904BHEP Ipc: C12P 13/22 20060101ALI20080904BHEP Ipc: C12N 9/10 20060101AFI20080904BHEP |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20100401 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: C07H 21/04 20060101ALI20100326BHEP Ipc: C12P 13/22 20060101ALI20100326BHEP Ipc: C12N 9/10 20060101AFI20080904BHEP |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: ZHAO, LISHAN Inventor name: WEINER, DAVID Inventor name: SOLHEID, CHRISTOPHER Inventor name: SANCHEZ-RIERA, FERNANDO A. Inventor name: RICHARDSON, TOBY Inventor name: MCFARLAN, SARA, C. Inventor name: LUGINBUHL, PETER Inventor name: KOLLMAN, SHERRY R. Inventor name: HICKS, PAULA M. Inventor name: GORT, STEVEN J. Inventor name: DE SOUZA, MERVYN Inventor name: BURKE, ELLEN Inventor name: BRAZEAU, BRIAN J. |
|
17Q | First examination report despatched |
Effective date: 20100722 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20110202 |