EP1867719A3 - Procédés et compositions d'inhibition de la croissance de cellules néoplasiques - Google Patents

Procédés et compositions d'inhibition de la croissance de cellules néoplasiques Download PDF

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Publication number
EP1867719A3
EP1867719A3 EP07005023A EP07005023A EP1867719A3 EP 1867719 A3 EP1867719 A3 EP 1867719A3 EP 07005023 A EP07005023 A EP 07005023A EP 07005023 A EP07005023 A EP 07005023A EP 1867719 A3 EP1867719 A3 EP 1867719A3
Authority
EP
European Patent Office
Prior art keywords
present
methods
polypeptides
compositions
cell growth
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP07005023A
Other languages
German (de)
English (en)
Other versions
EP1867719A2 (fr
Inventor
Kevin P. Baker
Audrey Goddard
Austin L. Gurney
Caroline Hebert
William Henzel
Rhona C. Kabakoff
David L. Shelton
Victoria Smith
Colin K. Watanabe
William I. Wood
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US1999/012252 external-priority patent/WO1999063088A2/fr
Priority claimed from PCT/US1999/020111 external-priority patent/WO2000012708A2/fr
Priority claimed from PCT/US1999/020594 external-priority patent/WO2000015666A2/fr
Priority claimed from PCT/US1999/028313 external-priority patent/WO2000032221A2/fr
Priority claimed from PCT/US1999/028634 external-priority patent/WO2000036102A2/fr
Priority claimed from PCT/US1999/028551 external-priority patent/WO2000053750A1/fr
Priority claimed from PCT/US1999/030095 external-priority patent/WO2000037640A2/fr
Priority claimed from PCT/US1999/030999 external-priority patent/WO2001005836A1/fr
Priority claimed from PCT/US2000/000376 external-priority patent/WO2000053755A2/fr
Priority claimed from PCT/US2000/003565 external-priority patent/WO2001053486A1/fr
Priority claimed from PCT/US2000/004342 external-priority patent/WO2000078961A1/fr
Priority claimed from PCT/US2000/004341 external-priority patent/WO2000053756A2/fr
Priority claimed from PCT/US2000/005841 external-priority patent/WO2000053758A2/fr
Priority claimed from PCT/US2000/006319 external-priority patent/WO2000053760A2/fr
Priority claimed from PCT/US2000/006884 external-priority patent/WO2001005972A1/fr
Priority claimed from PCT/US2000/008439 external-priority patent/WO2000073454A1/fr
Priority claimed from PCT/US2000/013705 external-priority patent/WO2000073445A2/fr
Application filed by Genentech Inc filed Critical Genentech Inc
Priority claimed from EP00941164A external-priority patent/EP1185648B1/fr
Publication of EP1867719A2 publication Critical patent/EP1867719A2/fr
Publication of EP1867719A3 publication Critical patent/EP1867719A3/fr
Withdrawn legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP07005023A 1999-06-02 2000-05-30 Procédés et compositions d'inhibition de la croissance de cellules néoplasiques Withdrawn EP1867719A3 (fr)

Applications Claiming Priority (24)

Application Number Priority Date Filing Date Title
PCT/US1999/012252 WO1999063088A2 (fr) 1998-06-02 1999-06-02 Proteines membranaires et acides nucleiques codant ces proteines
US14065099P 1999-06-22 1999-06-22
US14103799P 1999-06-23 1999-06-23
US14475899P 1999-07-20 1999-07-20
PCT/US1999/020111 WO2000012708A2 (fr) 1998-09-01 1999-09-01 Nouveaux pro-polypeptides et sequences correspondantes
PCT/US1999/020594 WO2000015666A2 (fr) 1998-09-10 1999-09-08 Compositions et methodes de traitement des tumeurs
US16250699P 1999-10-29 1999-10-29
PCT/US1999/028313 WO2000032221A2 (fr) 1998-12-01 1999-11-30 Promotion et inhibition de l'angiogenese et de la vascularisation cardiaque
PCT/US1999/028634 WO2000036102A2 (fr) 1998-12-16 1999-12-01 Polypeptides secretes et transmembranaires et acides nucleiques codant pour ceux-ci
PCT/US1999/028551 WO2000053750A1 (fr) 1999-03-08 1999-12-02 Compositions et procedes pour le traitement de tumeurs
US17026299P 1999-12-09 1999-12-09
PCT/US1999/030095 WO2000037640A2 (fr) 1998-12-22 1999-12-16 Compositions et methodes de traitement d'une tumeur
PCT/US1999/030999 WO2001005836A1 (fr) 1999-07-20 1999-12-20 Compositions polypeptidiques et methodes de traitement des tumeurs
PCT/US2000/000376 WO2000053755A2 (fr) 1999-03-08 2000-01-06 Compositions et procedes pour le traitement de tumeur
PCT/US2000/003565 WO2001053486A1 (fr) 1999-03-08 2000-02-11 Compositions et procedes destines au traitement de tumeur
PCT/US2000/004341 WO2000053756A2 (fr) 1999-03-08 2000-02-18 Polypeptides secretes et transmembranaires et acides nucleiques codant ces polypeptides
PCT/US2000/004342 WO2000078961A1 (fr) 1999-06-23 2000-02-18 Polypeptides secretes et transmembranaires et acides nucleiques codant pour ces polypeptides
PCT/US2000/005841 WO2000053758A2 (fr) 1999-03-08 2000-03-02 Compositions et methodes de traitement des maladies immunitaires
US18720200P 2000-03-03 2000-03-03
PCT/US2000/006319 WO2000053760A2 (fr) 1999-03-12 2000-03-10 Technique permettant de prevenir la mort des neurones retiniens et traitement des maladies oculaires
PCT/US2000/006884 WO2001005972A1 (fr) 1999-07-20 2000-03-15 Compositions et methodes pour traiter des maladies d'ordre immunologique
PCT/US2000/008439 WO2000073454A1 (fr) 1999-06-02 2000-03-30 Polypeptides transmembranaires secretes et acides nucleiques codants pour ceux-ci
PCT/US2000/013705 WO2000073445A2 (fr) 1999-06-02 2000-05-17 Promotion ou inhibition de l'angiogenese et de la cardiovascularisation
EP00941164A EP1185648B1 (fr) 1999-06-02 2000-05-30 Procedes et compositions visant a inhiber la proliferation des cellules cancereuses

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
EP00941164A Division EP1185648B1 (fr) 1999-06-02 2000-05-30 Procedes et compositions visant a inhiber la proliferation des cellules cancereuses

Publications (2)

Publication Number Publication Date
EP1867719A2 EP1867719A2 (fr) 2007-12-19
EP1867719A3 true EP1867719A3 (fr) 2008-03-19

Family

ID=50896660

Family Applications (4)

Application Number Title Priority Date Filing Date
EP07005021A Withdrawn EP1873244A3 (fr) 1999-06-02 2000-05-30 Procédés et compositions d'inhibition de la croissance de cellules néoplasiques
EP07004855A Withdrawn EP1820860A3 (fr) 1999-06-02 2000-05-30 Procédés et compositions d'inhibition de la croissance de cellules néoplasiques
EP07005022A Withdrawn EP1870464A3 (fr) 1999-06-02 2000-05-30 Procédés et compositions d'inhibition de la croissance de cellules néoplasiques
EP07005023A Withdrawn EP1867719A3 (fr) 1999-06-02 2000-05-30 Procédés et compositions d'inhibition de la croissance de cellules néoplasiques

Family Applications Before (3)

Application Number Title Priority Date Filing Date
EP07005021A Withdrawn EP1873244A3 (fr) 1999-06-02 2000-05-30 Procédés et compositions d'inhibition de la croissance de cellules néoplasiques
EP07004855A Withdrawn EP1820860A3 (fr) 1999-06-02 2000-05-30 Procédés et compositions d'inhibition de la croissance de cellules néoplasiques
EP07005022A Withdrawn EP1870464A3 (fr) 1999-06-02 2000-05-30 Procédés et compositions d'inhibition de la croissance de cellules néoplasiques

Country Status (1)

Country Link
EP (4) EP1873244A3 (fr)

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0315289A2 (fr) * 1987-11-06 1989-05-10 Oncogen Facteur inhibiteur de croissance cellulaire
WO1991015510A1 (fr) * 1990-04-03 1991-10-17 Bristol-Myers Squibb Company Epithelines: de nouvelles proteines modulatrices de la croissance riches en cysteine
WO1995009005A1 (fr) * 1993-09-29 1995-04-06 Bristol-Myers Squibb Company Procede de stimulation de la synthese de l'interleukine-6 et d'induction de la thrombocytopoiese a l'aide d'oncostatine m
WO2000001815A2 (fr) * 1998-07-06 2000-01-13 Nsgene A/S Facteurs neurotrophiques
WO2000004050A2 (fr) * 1998-07-14 2000-01-27 Janssen Pharmaceutica N.V. Facteur de croissance neurotrophique
WO2000017360A1 (fr) * 1998-09-22 2000-03-30 University Of Maryland, Baltimore Mutants du facteur de croissance a noeud de cystine
WO2000018799A1 (fr) * 1998-09-29 2000-04-06 Washington University L'artemine, un nouveau facteur neurotrophique
WO2000034475A2 (fr) * 1998-12-09 2000-06-15 Amgen Inc. Facteur de croissance neurotrophique issu des cellules gliales (grnf4), un facteur neurotrophique

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6004775A (en) * 1990-08-03 1999-12-21 The Salk Institute For Biological Studies DNA encoding IGFBP-4
WO1992003471A1 (fr) * 1990-08-28 1992-03-05 Chiron Corporation Nouvelle proteine de liaison de facteur de croissance analogue a l'insuline igfbp-5
EP0546074B1 (fr) * 1990-08-28 2001-11-14 Chiron Corporation Matiere genetique codant la ifgbp-5
US5824303A (en) * 1992-11-13 1998-10-20 Amgen Inc. Eck receptor ligands
AU685765B2 (en) * 1992-11-13 1998-01-29 Amgen, Inc. (Eck) receptor ligands
EP0835305B1 (fr) * 1995-06-29 2005-11-23 Immunex Corporation Cytokine inductrice d'apoptose
US6030945A (en) * 1996-01-09 2000-02-29 Genentech, Inc. Apo-2 ligand
AU5711196A (en) * 1996-03-14 1997-10-01 Human Genome Sciences, Inc. Apoptosis inducing molecule i
EP0918860A2 (fr) * 1996-06-07 1999-06-02 Amgen Inc. Polypeptide apparente au facteur de necrose tumorale
US6313269B1 (en) * 1997-03-14 2001-11-06 Smithkline Beecham Corporation Tumor necrosis factor related receptor, TR6
US20010010924A1 (en) * 1997-03-14 2001-08-02 Keith Charles Deen Tumor necrosis factor related receptor, tr6 polynecleotides
FR2766713B1 (fr) * 1997-08-04 1999-09-24 Bio Merieux Facteur proteique associe a une maladie neuro-degenerative et/ou auto-immune et/ou inflammatoire
DE69939732D1 (de) * 1998-01-15 2008-11-27 Genentech Inc Apo-2 ligand
JP2002512977A (ja) * 1998-04-29 2002-05-08 アラーガン・セイルズ・インコーポレイテッド クロストリディウム属細菌の神経毒の作用を延長させる組成物および方法
AU3365800A (en) * 1999-02-16 2000-09-04 Board Of Trustees Of The Leland Stanford Junior University Combined therapy of diterpenoid triepoxides and trail for synergistic killing oftumor cells
ATE348108T1 (de) * 1999-03-08 2007-01-15 Genentech Inc Methode zum nachweis von tumoren
AU3395900A (en) * 1999-03-12 2000-10-04 Human Genome Sciences, Inc. Human lung cancer associated gene sequences and polypeptides
AU3923000A (en) * 1999-04-16 2000-11-02 Amgen, Inc. Agp-1 fusion protein compositions and methods
JP4297317B2 (ja) * 1999-06-02 2009-07-15 ジェネンテック・インコーポレーテッド 血管形成及び心臓血管新生の促進又は阻害
EP2339003A3 (fr) * 1999-06-28 2011-10-19 Genentech, Inc. Polypeptides variants substitutionnels du ligand Apo-2

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0315289A2 (fr) * 1987-11-06 1989-05-10 Oncogen Facteur inhibiteur de croissance cellulaire
WO1991015510A1 (fr) * 1990-04-03 1991-10-17 Bristol-Myers Squibb Company Epithelines: de nouvelles proteines modulatrices de la croissance riches en cysteine
WO1995009005A1 (fr) * 1993-09-29 1995-04-06 Bristol-Myers Squibb Company Procede de stimulation de la synthese de l'interleukine-6 et d'induction de la thrombocytopoiese a l'aide d'oncostatine m
WO2000001815A2 (fr) * 1998-07-06 2000-01-13 Nsgene A/S Facteurs neurotrophiques
WO2000004050A2 (fr) * 1998-07-14 2000-01-27 Janssen Pharmaceutica N.V. Facteur de croissance neurotrophique
WO2000017360A1 (fr) * 1998-09-22 2000-03-30 University Of Maryland, Baltimore Mutants du facteur de croissance a noeud de cystine
WO2000018799A1 (fr) * 1998-09-29 2000-04-06 Washington University L'artemine, un nouveau facteur neurotrophique
WO2000034475A2 (fr) * 1998-12-09 2000-06-15 Amgen Inc. Facteur de croissance neurotrophique issu des cellules gliales (grnf4), un facteur neurotrophique

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BALOH R H ET AL: "ARTEMIN, A NOVEL MEMBER OF THE GDNF LIGAND FAMILY, SUPPORTS PERIPHERAL AND CENTRAL NEURONS AND SIGNALS THROUGH THE GFRALPHA3- RET RECEPTOR COMPLEX", NEURON, CAMBRIDGE, MA, US, vol. 21, no. 6, December 1998 (1998-12-01), pages 1291 - 1302, XP000857438 *
MASURE S ET AL: "ENOVIN A MEMBER OF THE GLIAL CELL-LINE-DERIVED NEUROTROPHIC FACTOR (GDNF) FAMILIY WITH GROWTH PROMOTING ACTIVITY ON NEURONAL CELLS", EUROPEAN JOURNAL OF BIOCHEMISTRY, BERLIN, DE, vol. 266, no. 3, 1999, pages 892 - 902, XP000882986, ISSN: 0014-2956 *
ROSENBLAD C ET AL: "In vivo protection of nigral dopamine neurons by lentiviral gene transfer of the novel GDNF-family member neublastin/artemin", MOLECULAR AND CELLULAR NEUROSCIENCES, SAN DIEGO, US, vol. 15, no. 2, February 2000 (2000-02-01), pages 199 - 214, XP002262602, ISSN: 1044-7431 *

Also Published As

Publication number Publication date
EP1820860A2 (fr) 2007-08-22
EP1870464A3 (fr) 2008-03-12
EP1870464A8 (fr) 2008-02-27
EP1873244A8 (fr) 2008-02-27
EP1820860A3 (fr) 2008-03-19
EP1867719A2 (fr) 2007-12-19
EP1870464A2 (fr) 2007-12-26
EP1873244A2 (fr) 2008-01-02
EP1873244A3 (fr) 2008-04-02

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