AU3365800A - Combined therapy of diterpenoid triepoxides and trail for synergistic killing oftumor cells - Google Patents

Combined therapy of diterpenoid triepoxides and trail for synergistic killing oftumor cells

Info

Publication number
AU3365800A
AU3365800A AU33658/00A AU3365800A AU3365800A AU 3365800 A AU3365800 A AU 3365800A AU 33658/00 A AU33658/00 A AU 33658/00A AU 3365800 A AU3365800 A AU 3365800A AU 3365800 A AU3365800 A AU 3365800A
Authority
AU
Australia
Prior art keywords
trail
combined therapy
synergistic killing
oftumor
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU33658/00A
Inventor
Glenn D. Rosen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leland Stanford Junior University
Original Assignee
Leland Stanford Junior University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leland Stanford Junior University filed Critical Leland Stanford Junior University
Publication of AU3365800A publication Critical patent/AU3365800A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU33658/00A 1999-02-16 2000-02-15 Combined therapy of diterpenoid triepoxides and trail for synergistic killing oftumor cells Abandoned AU3365800A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12031399P 1999-02-16 1999-02-16
US60120313 1999-02-16
PCT/US2000/003891 WO2000048619A1 (en) 1999-02-16 2000-02-15 Combined therapy of diterpenoid triepoxides and trail for synergistic killing of tumor cells

Publications (1)

Publication Number Publication Date
AU3365800A true AU3365800A (en) 2000-09-04

Family

ID=22389505

Family Applications (1)

Application Number Title Priority Date Filing Date
AU33658/00A Abandoned AU3365800A (en) 1999-02-16 2000-02-15 Combined therapy of diterpenoid triepoxides and trail for synergistic killing oftumor cells

Country Status (2)

Country Link
AU (1) AU3365800A (en)
WO (1) WO2000048619A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1867719A3 (en) * 1999-06-02 2008-03-19 Genentech, Inc. Methods and compositions for inhibiting neoplastic cell growth
US6294546B1 (en) 1999-08-30 2001-09-25 The Broad Of Trustees Of The Leland Stanford Junior University Uses of diterpenoid triepoxides as an anti-proliferative agent
US9150600B2 (en) 2009-05-07 2015-10-06 Regents Of The University Of Minnesota Triptolide prodrugs
PT2427467E (en) 2009-05-07 2015-11-19 Univ Minnesota Triptolide prodrugs
JP7353500B2 (en) * 2019-12-30 2023-09-29 グゥアンドン プロビンシャル ホスピタル オブ ティーシーエム Acrylic acid triptolide, its preparation method and uses
CN114642670B (en) * 2022-03-30 2023-05-12 华侨大学 Application of triptolide derivative in preparing medicament for treating tumor drug resistance and pharmaceutical composition for treating tumor drug resistance

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5994298A (en) * 1997-12-18 1999-11-30 Tsai; David Proteins for cancer cell specific induction of apoptosis and method for isolation thereof

Also Published As

Publication number Publication date
WO2000048619A1 (en) 2000-08-24

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase