EP1805300A4 - Differenzierungmenschlicher mesenchymaler stammzellen zu die herzreparatur fördernden herzvorläuferzellen - Google Patents

Differenzierungmenschlicher mesenchymaler stammzellen zu die herzreparatur fördernden herzvorläuferzellen

Info

Publication number
EP1805300A4
EP1805300A4 EP05812162A EP05812162A EP1805300A4 EP 1805300 A4 EP1805300 A4 EP 1805300A4 EP 05812162 A EP05812162 A EP 05812162A EP 05812162 A EP05812162 A EP 05812162A EP 1805300 A4 EP1805300 A4 EP 1805300A4
Authority
EP
European Patent Office
Prior art keywords
cardiac
differentiation
mesenchymal stem
human mesenchymal
stem cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP05812162A
Other languages
English (en)
French (fr)
Other versions
EP1805300A2 (de
Inventor
Ira S Cohen
Michael R Rosen
Richard B Robinson
Peter R Brink
Glenn Gaudette
Irina Potapova
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Research Foundation of State University of New York
Columbia University in the City of New York
Original Assignee
Research Foundation of State University of New York
Columbia University in the City of New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Research Foundation of State University of New York, Columbia University in the City of New York filed Critical Research Foundation of State University of New York
Publication of EP1805300A2 publication Critical patent/EP1805300A2/de
Publication of EP1805300A4 publication Critical patent/EP1805300A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0657—Cardiomyocytes; Heart cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/90—Substrates of biological origin, e.g. extracellular matrix, decellularised tissue
    • C12N2533/92—Amnion; Decellularised dermis or mucosa

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Cardiology (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
EP05812162A 2004-09-14 2005-09-14 Differenzierungmenschlicher mesenchymaler stammzellen zu die herzreparatur fördernden herzvorläuferzellen Withdrawn EP1805300A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94103404A 2004-09-14 2004-09-14
PCT/US2005/033422 WO2006032054A2 (en) 2004-09-14 2005-09-14 Differentiation of human mesenchymal stem cells to cardiac progenitor cells that promote cardiac repair

Publications (2)

Publication Number Publication Date
EP1805300A2 EP1805300A2 (de) 2007-07-11
EP1805300A4 true EP1805300A4 (de) 2009-09-09

Family

ID=36060741

Family Applications (1)

Application Number Title Priority Date Filing Date
EP05812162A Withdrawn EP1805300A4 (de) 2004-09-14 2005-09-14 Differenzierungmenschlicher mesenchymaler stammzellen zu die herzreparatur fördernden herzvorläuferzellen

Country Status (2)

Country Link
EP (1) EP1805300A4 (de)
WO (1) WO2006032054A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006015127A2 (en) 2004-07-30 2006-02-09 Mayo Foundation For Medical Education And Research Treating cardiovascular tissue
US8431397B2 (en) 2004-09-14 2013-04-30 The Trustees Of Columbia University In The City Of New York Differentiation of human mesenchymal stem cells to cardiac progenitor cells that promote cardiac repair
EP1984488B1 (de) * 2006-01-30 2017-12-27 University Of Virginia Patent Foundation Verfahren zur herstellung und charakterisierung mesenchymaler stammzellaggregate und ihre verwendung
US9765298B2 (en) 2006-07-24 2017-09-19 Mayo Foundation For Medical Education And Research Methods and materials for providing cardiac cells
US8835170B2 (en) 2006-10-06 2014-09-16 University Of Virginia Patent Foundation Methods and compositions useful for diabetic wound healing
US20100189697A1 (en) * 2007-03-07 2010-07-29 Andre Terzic Cardiac-specific progenitor cells
WO2009145761A1 (en) 2008-05-27 2009-12-03 Mayo Foundation For Medical Education And Research Methods and materials for using cells to treat heart tissue
EP3796876B1 (de) 2018-05-22 2022-07-27 Boston Scientific Scimed, Inc. Perkutane papillarmuskelumlagerung

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006029084A2 (en) * 2004-09-03 2006-03-16 Cornell Research Foundation, Inc. Bone marrow derived oct3/4+ stem cells

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19525285C2 (de) * 1995-06-28 1999-04-15 Inst Pflanzengenetik & Kultur In vitro Testverfahren zum Nachweis Chemikalien-induzierter embryotoxischer/teratogener Effekte
EP1165830B1 (de) * 1999-03-10 2017-07-12 University of Pittsburgh of the Commonwealth System of Higher Education Aus fettgewebe stammende stammzellen und gitter
US6818757B2 (en) * 2000-01-14 2004-11-16 Beth Israel Deaconess Medical Center Cardiac-cell specific enhancer elements and uses thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006029084A2 (en) * 2004-09-03 2006-03-16 Cornell Research Foundation, Inc. Bone marrow derived oct3/4+ stem cells

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
ASSMUS BIRGIT ET AL: "Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction (TOPCARE-AMI).", CIRCULATION, vol. 106, no. 24, 10 December 2002 (2002-12-10), pages 3009 - 3017, XP002538784, ISSN: 0009-7322 *
DOEVENDANS P A ET AL: "Differentiation of cardiomyocytes in floating embryoid bodies is comparable to fetal cardiomyocytes", JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 2000 GB, vol. 32, no. 5, 2000, pages 839 - 851, XP002538787, ISSN: 0022-2828 *
OSHIMA Y ET AL: "Fate of transplanted bone-marrow-derived mesenchymal cells during osteochondral repair using transgenic rats to simulate autologous transplantation", OSTEOARTHRITIS AND CARTILAGE 200410 GB, vol. 12, no. 10, October 2004 (2004-10-01), pages 811 - 817, XP004573247, ISSN: 1063-4584 *
RANGAPPA S ET AL: "Cardiomyocyte-mediated contact programs human mesenchymal stem cells to express cardiogenic phenotype", JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY 20030701 US, vol. 126, no. 1, 1 July 2003 (2003-07-01), pages 124 - 132, XP002538786, ISSN: 0022-5223 *
WERTMAN BRETT ET AL: "A novel approach to discern the cardiomyogenic capability of human mesenchymal stem cells", JOURNAL OF INVESTIGATIVE MEDICINE, vol. 49, no. 1, January 2001 (2001-01-01), & JOINT REGIONAL MEETING OF THE WESTERN SECTION AMERICAN FEDERATION FOR MEDICAL RESEARCH, THE WESTERN; CARMEL, CALIFORNIA, USA; FEBRUARY 07-10, 2001, pages 67A, XP009120647, ISSN: 1081-5589 *
XU WENRONG ET AL: "Mesenchymal stem cells from adult human bone marrow differentiate into a cardiomyocyte phenotype in vitro", EXPERIMENTAL BIOLOGY AND MEDICINE (MAYWOOD), vol. 229, no. 7, July 2004 (2004-07-01), pages 623 - 631, XP002538785, ISSN: 1535-3702 *

Also Published As

Publication number Publication date
EP1805300A2 (de) 2007-07-11
WO2006032054A2 (en) 2006-03-23
WO2006032054A9 (en) 2006-05-26
WO2006032054A3 (en) 2009-04-16

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