EP1778266A4 - COMPOSITIONS AND METHODS FOR PREVENTING AND REGULATING INSULIN-INDUCED HYPOGLYCEMIA - Google Patents

COMPOSITIONS AND METHODS FOR PREVENTING AND REGULATING INSULIN-INDUCED HYPOGLYCEMIA

Info

Publication number
EP1778266A4
EP1778266A4 EP05787795A EP05787795A EP1778266A4 EP 1778266 A4 EP1778266 A4 EP 1778266A4 EP 05787795 A EP05787795 A EP 05787795A EP 05787795 A EP05787795 A EP 05787795A EP 1778266 A4 EP1778266 A4 EP 1778266A4
Authority
EP
European Patent Office
Prior art keywords
insulin
prevention
compositions
methods
control
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP05787795A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP1778266A2 (en
Inventor
Daniel T Green
Robert R Henry
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DiObex Inc
Original Assignee
DiObex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DiObex Inc filed Critical DiObex Inc
Publication of EP1778266A2 publication Critical patent/EP1778266A2/en
Publication of EP1778266A4 publication Critical patent/EP1778266A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/26Glucagons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/28Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Endocrinology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Obesity (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP05787795A 2004-06-29 2005-06-27 COMPOSITIONS AND METHODS FOR PREVENTING AND REGULATING INSULIN-INDUCED HYPOGLYCEMIA Withdrawn EP1778266A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58444904P 2004-06-29 2004-06-29
PCT/US2005/022812 WO2006004696A2 (en) 2004-06-29 2005-06-27 Compositions and methods for the prevention and control of insulin-induced hypoglycemia

Publications (2)

Publication Number Publication Date
EP1778266A2 EP1778266A2 (en) 2007-05-02
EP1778266A4 true EP1778266A4 (en) 2009-09-09

Family

ID=35783298

Family Applications (1)

Application Number Title Priority Date Filing Date
EP05787795A Withdrawn EP1778266A4 (en) 2004-06-29 2005-06-27 COMPOSITIONS AND METHODS FOR PREVENTING AND REGULATING INSULIN-INDUCED HYPOGLYCEMIA

Country Status (11)

Country Link
EP (1) EP1778266A4 (enExample)
JP (1) JP2008505087A (enExample)
KR (1) KR20070029276A (enExample)
CN (1) CN101001638A (enExample)
AU (1) AU2005260025A1 (enExample)
CA (1) CA2571030A1 (enExample)
IL (1) IL180361A0 (enExample)
MX (1) MXPA06014970A (enExample)
NO (1) NO20070174L (enExample)
WO (1) WO2006004696A2 (enExample)
ZA (1) ZA200700708B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2816114C (en) 2010-11-03 2019-02-12 Jan Jezek Novel composition comprising glucagon
CN107949374B (zh) * 2015-09-04 2022-04-08 莱迪杜德制药公司 稳定的胰高血糖素溶液
GB201611077D0 (en) 2016-06-24 2016-08-10 Arecor Ltd Novel composition
CN110446496A (zh) * 2017-02-03 2019-11-12 范德比尔特大学 用于治疗糖尿病的系统、组合物和方法
BR112020000447A2 (pt) * 2017-07-14 2020-07-21 Xeris Pharmaceuticals, Inc. métodos de tratamento de hiperinsulinismo congênito
WO2019108640A1 (en) * 2017-11-28 2019-06-06 The Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Methods and kits for evaluating metabolism
WO2021263197A1 (en) * 2020-06-26 2021-12-30 Xeris Pharmaceuticals, Inc. Stable sustained release therapeutic compositions in aprotic polar solvents and methods of manufacturing the same
GB202109087D0 (en) * 2021-06-24 2021-08-11 Norwegian Univ Sci & Tech Ntnu Therapeutic methods and devices

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004060387A1 (en) * 2002-12-27 2004-07-22 Diobex, Inc. Compositions and methods for the prevention and control of insulin-induced hypoglycemia

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3897551A (en) * 1971-04-05 1975-07-29 Lilly Co Eli Iodoglucagons and process for prolonging the biological activity of glucagon
US5321008A (en) * 1991-01-10 1994-06-14 Amylin Pharmaceuticals, Inc. Methods and compositions for treatment of diabetes mellitus, hypoglycemia, and other conditions
WO2004046106A1 (en) * 2002-11-18 2004-06-03 Pfizer Products Inc. Dipeptidyl peptidase iv inhibiting fluorinated cyclic amides

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004060387A1 (en) * 2002-12-27 2004-07-22 Diobex, Inc. Compositions and methods for the prevention and control of insulin-induced hypoglycemia

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
CRYER PHILIP E ET AL: "Hypoglycemia in diabetes.", DIABETES CARE JUN 2003, vol. 26, no. 6, June 2003 (2003-06-01), pages 1902 - 1912, XP002538099, ISSN: 0149-5992 *
DE GALAN B E ET AL: "Pathophysiology and management of recurrent hypoglycaemia and hypoglycaemia unawareness in diabetes", NETHERLANDS JOURNAL OF MEDICINE, vol. 64, no. 8, September 2006 (2006-09-01), pages 269 - 279, XP002538100, ISSN: 0300-2977 *
EDELMAN S V ET AL: "Subcutaneous infusion of very low dose-glucagon averts insulin induced hypoglycaemia in patients with type 1 diabetes mellitus", DIABETOLOGIA, vol. 49, no. Suppl. 1, September 2006 (2006-09-01), & 42ND ANNUAL MEETING OF THE EUROPEAN-ASSOCIATION-FOR-THE-STUDY-OF-DIA BETES (EASD); COPENHAGEN, DENMARK; SEPTEMBER 14 -17, 2006, pages 506, XP009120428, ISSN: 0012-186X *
EDELMAN STEVEN ET AL: "Nocturnal administration of very low dose glucagon in patients with type 1 diabetes reduces episodes of nocturnal hypoglycemia", DIABETES, vol. 56, no. Suppl. 1, June 2007 (2007-06-01), & 67TH ANNUAL MEETING OF THE AMERICAN-DIABETES-ASSOCIATION; CHICAGO, IL, USA; JUNE 22 -26, 2007, pages A8 - A9, XP009120378, ISSN: 0012-1797 *
FANELLI C G ET AL: "Glucagon: the effects of its excess and deficiency on insulin action.", NUTRITION, METABOLISM, AND CARDIOVASCULAR DISEASES : NMCD MAR 2006, vol. 16 Suppl 1, March 2006 (2006-03-01), pages S28 - S34, XP002538101, ISSN: 0939-4753 *
HAYMOND M W ET AL: "Mini-dose glucagon rescue for hypoglycemia in children with type 1 diabetes.", DIABETES CARE APR 2001, vol. 24, no. 4, April 2001 (2001-04-01), pages 643 - 645, XP002538098, ISSN: 0149-5992 *
ISLEY WILLIAM ET AL: "Very low dose glucagon averts insulin induced Hypoglycemia in patients with type 1 diabetes", DIABETES, vol. 55, no. Suppl. 1, June 2006 (2006-06-01), & 66TH ANNUAL MEETING OF THE AMERICAN-DIABETES-ASSOCIATION; WASHINGTON, DC, USA; JUNE 09 -13, 2006, pages A117, XP009120392, ISSN: 0012-1797 *

Also Published As

Publication number Publication date
IL180361A0 (en) 2007-06-03
KR20070029276A (ko) 2007-03-13
CN101001638A (zh) 2007-07-18
WO2006004696A2 (en) 2006-01-12
AU2005260025A1 (en) 2006-01-12
MXPA06014970A (es) 2007-03-07
EP1778266A2 (en) 2007-05-02
JP2008505087A (ja) 2008-02-21
NO20070174L (no) 2007-03-13
CA2571030A1 (en) 2006-01-12
ZA200700708B (en) 2009-03-25
WO2006004696A3 (en) 2006-10-26

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