EP1766041A2

EP1766041A2 - Methods for identifying risk of breast cancer and treatment thereof

Info

Publication number: EP1766041A2
Application number: EP04753721A
Authority: EP
Inventors: Richard B. Roth; Matthew Roberts Nelson; Andreas Braun; Stefan M. Kammerer; Rikard Reneland; Caridad Rosette; Mikhail F. Denissenko; Jonas Göran EKBLOM; Carolyn R. Hoyal-Wrightson
Original assignee: Sequenom Inc
Current assignee: Sequenom Inc
Priority date: 2004-05-27
Filing date: 2004-05-27
Publication date: 2007-03-28
Also published as: WO2005118834A3; CA2569100A1; WO2005118834A2

Abstract

Provided herein are methods for identifying risk of breast cancer in a subject and/or a subject at risk of breast cancer, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for treating breast cancer, and therapeutic methods for treating breast cancer in a subject. These embodiments are based upon an analysis of polymorphic variations in nucleotide sequences within the human genome.

Description

METHODS FORIDENTIFYINGRISKOFBREAST CANCER AND TREATMENTS THEREOF

Field ofthe Invention [0001] The invention relates to genetic methods for identifying risk of breast cancer and treatments that specifically target the disease.

Background [0002] Breast cancer is the third most common cancer, and the most common cancer in women, as well as a cause of disability, psychological trauma, and economic loss. Breast cancer is the second most common cause of cancer death in women in the United States, in particular for women between the ages of 15 and 54, and the leading cause of cancer-related death (Forbes, Seminars in Oncology, vol.24(l), Suppl 1, 1997: pp.Sl-20-Sl-35). Indirect effects ofthe disease also contribute to the mortality from breast cancer including consequences of advanced disease, such as metastases to the bone or brain. Complications arising from bone marrow suppression, radiation fibrosis and neutropenic sepsis, collateral effects from therapeutic interventions, such as surgery, radiation, chemotherapy, or bone marrow transplantation-also contribute to the morbidity and mortality from this disease. [0003] While the pathogenesis of breast cancer is unclear, transformation of normal breast epithelium to a malignant phenotype may be the result of genetic factors, especially in women under thirty (Miki, et al, Science, 266: 66-71 (1994)). However, it is likely that other, non-genetic factors also have a significant effect on the etiology ofthe disease. Regardless of its origin, breast cancer morbidity increases significantly if it is not detected early in its progression. Thus, considerable efforts have focused on the elucidation of early cellular events surrounding transformation in breast tissue. Such efforts have led to the identification of several potential breast cancer markers. For example, alleles ofthe BRCA1 and BRCA2 genes have been linked to hereditary and early-onset breast cancer (Wooster, et al, Science, 265: 2088-2090 (1994)). However, BRCA1 is limited as a cancer marker because BRCA1 mutations fail to account for the majority of breast cancers (Ford, et al, British J. Cancer, 72: 805-812 (1995)). Similarly, the BRCA2 gene, which has been linked to forms of hereditary breast cancer, accounts for only a small portion of total breast cancer cases. Summary [0004] It has been discovered that certain polymorphic variations in human genomic DNA are associated with the occurrence of breast cancer. In particular, polymorphic variants in loci containing SPUVE, GRIN3A, PFTK1, SERPINA5, LOCI 15209 and HRMT1L3 regions in human genomic DNA have been associated with risk of breast cancer. [0005] Thus, featured herein are methods for identifying a subject at risk of breast cancer and/or a risk of breast cancer in a subject, which comprises detecting the presence or absence of one or more polymorphic variations associated with breast cancer in genomic regions described herein in a human nucleic acid sample. In an embodiment, two or more polymoφhic variations are detected in two or more regions selected from the group consisting of SPUVE, GRIN3A, PFTK1, SERPINA5, LOCI 15209 and HRMT1L3. In certain embodiments, 3 or fewer, or 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19 or 20 or fewer polymorphic variants are detected. [0006] Also featured are nucleic acids that include one or more polymorphic variations associated with the occurrence of breast cancer, as well as polypeptides encoded by these nucleic acids. Further, provided is a method for identifying a subject at risk of breast cancer and then prescribing to the subject a breast cancer detection procedure, prevention procedure and/or a treatment procedure. In addition, provided are methods for identifying candidate therapeutic molecules for treating breast cancer and related disorders, as well as methods for treating breast cancer in a subject by diagnosing breast cancer in the subject and treating the subject with a suitable treatment, such as administering a therapeutic molecule. [0007] Also provided are compositions comprising a breast cancer cell and/or SPUVE, GRIN3A, PFTK1, SERPINA5, LOCI 15209 or HRMT1L3 nucleic acid with a RNAi, siRNA, antisense DNA or RNA, or ribozyme nucleic acid designed from a SPUVE, GRIN3A, PFTK1, SERPINA5, LOCI 15209 or HRMT1L3 nucleotide sequence. In an embodiment, the nucleic acid is designed from a SPUVE, GRIN3A, PFTK1, SERPINA5, LOCI 15209 or HRMT1L3 nucleotide sequence that includes one or more breast cancer associated polymoφhic variations, and in some instances, specifically interacts with such a nucleotide sequence. Further, provided are arrays of nucleic acids bound to a solid surface, in which one or more nucleic acid molecules ofthe array have a SPUVE, GRIN3A, PFTK1, SERPINA5, LOCI 15209 or HRMT1L3 nucleotide sequence, or a fragment or substantially identical nucleic acid thereof, or a complementary nucleic acid ofthe foregoing. Featured also are compositions comprising a breast cancer cell and/or a SPUVE, GRIN3A, PFTK1, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide, with an antibody that specifically binds to the polypeptide. In an embodiment, the antibody specifically binds to an epitope in the polypeptide that includes a non-synonymous amino acid modification associated with breast cancer (e.g., results in an amino acid substitution in the encoded polypeptide associated with breast cancer). In certaiα embodiments, the antibody specifically binds to an epitope that comprises a lysine at amino acid position 105 in SEQ ID NO: 16 of a SERPINA5 polypeptide.

Brief Description ofthe Figures [0008] Figures lAto IF show proximal SNPs in SPUVE, GRIN3A, PFTK1, SERPINA5, LOCI 15209 and HRMT1L3 regions of genomic DNA, respectively. The position of each SNP on the chromosome is shown on the x-axis and the y-axis provides the negative logarithm ofthe p- value comparing the estimated allele to that ofthe control group. Also shown in the figure are exons and introns ofthe regions in the approximate chromosomal positions.

Detailed Description [0009] It has been discovered that polymoφhic variations in the SPUVE, GRIN3A, PFTK1, SERPINA5, LOCH 5209 and HRMT1L3 regions described herein are associated with an increased risk of breast cancer. [0010] The gene SPUVE (protease, serine, 23) is also known as ZSIG13, MGC5107, PRSS23. SPUVE has been mapped to chromosomal position 1 lql4.1. The gene for SPUVE encodes a member ofthe trypsin family of serine proteases. Its specific function is unknown [0011] The gene GRIN3A (glutamate receptor, ionotropic, N-methyl-D-aspartate 3 A) is also known as NR3 A, NMDAR-L. GRIN3A has been mapped to chromosomal position 9q31.1. This gene encodes a subunit ofthe N-methyl-D-aspartate (NMDA) receptors, which belong to the superfamily of glutamate-regulated ion channels, and function in physiological and pathological processes in the central nervous system. This subunit shows greater than 90% identity to the corresponding subunit in rat. Studies in the knockout mouse deficient in this subunit suggest that this gene may be involved in the development of synaptic elements by modulating NMDA receptor activity. ' [0012] The gene PFTK (PFTAJRE protein kinase 1) is also known as KIAA0834, PFTAIREl . PFTK has been mapped to chromosomal position 7q21-q22. Interaction of PFTAIRE-1 with Septin 8 has been identified by Y2H. Septins are known protooncogenes, involved in cytokinesis, and interact with actin, actin-binding proteins, proteins of membrane fusion machinery, Cdc42 adapter proteins, a ubiquitin-protein ligase, and phosphoinositides. [0013] The gene SERPINA5 (serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5) is also known as PCI, PAI3, PROCI, PLANH3. SERPL A5 has been mapped to chromosomal position 14q32.1. Activated protein C is a potent anticoagulant. Suzuki et al. (1987) determined the sequence of cDNA for human protein C inhibitor (PCI). A high degree of homology ofthe deduced amino acid sequence to that of other known inhibitors clearly demonstrated that protein C inhibitor is a member ofthe superfamily of serine protease inhibitors including alρha-1-antichymotrypsin (AACT; NCBI MLM 107280), alpha-1 -antitrypsin (AAT; PI; NCBI MLM 107400), antithrombin DI (AT3; NCBI MTM 107300), and angiotensinogen (AGT; NCBI MLM 106150). Suzuki, K. et al. Characterization of a cDNA for human protein C inhibitor: a new member ofthe plasma serine protease inhibitor superfamily. J. Biol. Chem. 262: 611-616, 1987. [0014] The gene LOCI 15209 is also known as MPRP-1 (metalloprotease related protein 1). LOCI 15209 has been mapped to chromosomal position lp32.1. This gene is related to metallo- and prenyl proteases. Prenyl proteases are important in ras function (membrane insertion). [0015] The gene HRMT1L3 stands for (HMT1 hnRNP methyltransferase-like 3 (S. cerevisiae). HRMT1L3 has been mapped to chromosomal position 12pl3.3. HRMT1L3 is highly similar to HRMT1L2 and is likely a protein-arginine N methyltransferase 1. Its probable functions include the regulation of translation, export of specific rnRNAs, possible regulator of transcription. It has a possible interaction with AIR RING finger proteins.

Breast Cancer and Sample Selection [0016] Breast cancer is typically described as the uncontrolled growth of malignant breast tissue. Breast cancers arise most commonly in the lining ofthe milk ducts ofthe breast (ductal carcinoma), or in the lobules where breast milk is produced (lobular carcinoma). Other forms of breast cancer include Inflammatory Breast Cancer and Recurrent Breast Cancer. Inflammatory breast cancer is a rare, but very serious, aggressive type of breast cancer. The breast may look red and feel warm with ridges, welts, or hives on the breast; or the skin may look wrinkled. It is sometimes misdiagnosed as a simple infection. Recurrent disease means that the cancer has come back after it has been treated. It may come back in the breast, in the soft tissues ofthe chest (the chest wall), or in another part ofthe body. [0017] As used herein, the term "breast cancer" refers to a condition characterized by anomalous rapid proliferation of abnormal cells in one or both breasts of a subject. The abnormal cells often are referred to as "neoplastic cells," which are transformed cells that can form a solid tumor. The term "tumor" refers to an abnormal mass or population of cells (i.e. two or more cells) that result from excessive or abnormal cell division, whether malignant or benign, and precancerous and cancerous cells. Malignant tumors are distinguished from benign growths or tumors in that, in addition to uncontrolled cellular proliferation, they can invade surrounding tissues and can metastasize. In breast cancer, neoplastic cells may be identified in one or both breasts only and not in another tissue or organ, in one or both breasts and one or more adjacent tissues or organs (e.g. lymph node), or in a breast and one or more non-adjacent tissues or organs to which the breast cancer cells have metastasized. [0018] The term "invasion" as used herein refers to the spread of cancerous cells to adjacent surrounding tissues. The term "invasion" often is used synonymously with the term "metastasis," which as used herein refers to a process in which cancer cells travel from one organ or tissue to another non-adjacent organ or tissue. Cancer cells in the breast(s) can spread to tissues and organs of a subject, and conversely, cancer cells from other organs or tissue can invade or metastasize to a breast. Cancerous cells from the breast(s) may invade or metastasize to any other organ or tissue of the body. Breast cancer cells often invade lymph node cells and/or metastasize to the liver, brain and/or bone and spread cancer in these tissues and organs. Breast cancers can spread to other organs and tissues and cause lung cancer, prostate cancer, colon cancer, ovarian cancer, cervical cancer, gastrointestinal cancer, pancreatic cancer, glioblastoma, bladder cancer, hepatoma, colorectal cancer, uterine cervical cancer, endometrial carcinoma, salivary gland carcinoma, kidney cancer, vulval cancer, thyroid cancer, hepatic carcinoma, skin cancer, melanoma, ovarian cancer, neuroblastoma, myeloma, various types of head and neck cancer, acute lymphoblastic leukemia, acute myeloid leukemia, Ewing sarcoma and peripheral neuroepithelioma, and other carcinomas, lymphomas, blastomas, sarcomas, and leukemias. , [0019] Breast cancers arise most commonly in the lining ofthe milk ducts ofthe breast (ductal carcinoma), or in the lobules where breast milk is produced (lobular carcinoma). Other forms of breast cancer include Inflammatory Breast Cancer and Recurrent Breast Cancer. Inflammatory Breast Cancer is a rare, but very serious, aggressive type of breast cancer. The breast may look red and feel warm with ridges, welts, or hives on the breast; or the skin may look wrinkled. It is sometimes misdiagnosed as a simple infection. Recurrent disease means that the cancer has come back after it has been treated. It may come back in the breast, in the soft tissues ofthe chest (the chest wall), or in another part ofthe body. As used herein, the term "breast cancer" may include both Inflammatory Breast Cancer and Recurrent Breast Cancer. [0020] In an effort to detect breast cancer as early as possible, regular physical exams and screening mammograms often are prescribed and conducted. A diagnostic mammogram often is performed to evaluate a breast complaint or abnormality detected by physical exam or routine screening mammography. If an abnormality seen with diagnostic mammography is suspicious, additional breast imaging (with exams such as ultrasound) or a biopsy may be ordered. A biopsy followed by pathological (microscopic) analysis is a definitive way to determine whether a subject has breast cancer. Excised breast cancer samples often are subjected to the following analyses: diagnosis ofthe breast tumor and confirmation of its malignancy; maximum tumor thickness; assessment of completeness of excision of invasive and in situ components and microscopic measurements ofthe shortest extent of clearance; level of invasion; presence and extent of regression; presence and extent of ulceration; histological type and special variants; pre-existing lesion; mitotic rate; vascular invasion; neurotropism; cell type; tumor lymphocyte infiltration; and growth phase. [0021] The stage of a breast cancer can be classified as a range of stages from Stage 0 to Stage IV based on its size and the extent to which it has spread. The following table summarizes the stages:

Table A

[0022] Stage 0 cancer is a contained cancer that has not spread beyond the breast ductal system. Fifteen to twenty percent of breast cancers detected by clinical examinations or testing are in Stage 0 (the earliest form of breast cancer). Two types of Stage 0 cancer are lobular carcinoma in situ (LCIS) and ductal carcinoma in situ (DCIS). LCIS indicates high risk for breast cancer. Many physicians do not classify LCIS as a malignancy and often encounter LCIS by chance on breast biopsy while investigating another area of concern. While the microscopic features of LCIS are abnormal and are similar to malignancy, LCIS does not behave as a cancer (and therefore is not treated as a cancer). LCIS is merely a marker for a significantly increased risk of cancer anywhere in the breast. However, bilateral simple mastectomy may be occasionally performed if LCIS patients have a strong family history of breast cancer. In DCIS the cancer cells are confined to milk ducts in the breast and have not spread into the fatty breast tissue or to any other part ofthe body (such as the lymph nodes). DCIS may be detected on mammogram as tiny specks of calcium (known as microcalcifications) 80% ofthe time. Less commonly DCIS can present itself as a mass with calcifications (15% ofthe time); and even less likely as a mass without calcifications (<5% of the time). A breast biopsy is used to confirm DCIS. A standard DCIS treatment is breast- conserving therapy (BCT), which is lumpectomy followed by radiation treatment or mastectomy. To date, DCIS patients have chosen equally among lumpectomy and mastectomy as their treatment option, though specific cases may sometimes favor lumpectomy over mastectomy or vice versa. [0023] In Stage I, the primary (original) cancer is 2 cm or less in diameter and has not spread to the lymph nodes. In Stage DA, the primary tumor is between 2 and 5 cm in diameter and has not spread to the lymph nodes. In Stage LOB, the primary tumor is between 2 and 5 cm in diameter and has spread to the axillary (underarm) lymph nodes; or the primary tumor is over 5 cm and has not spread to the lymph nodes. In Stage IDA, the primary breast cancer of any kind that has spread to the axillary (underarm) lymph nodes and to axillary tissues. In Stage DIB, the primary breast cancer is any size, has attached itself to the chest wall, and has spread to the pectoral (chest) lymph nodes. In Stage TV, the primary cancer has spread out ofthe breast to other parts ofthe body (such as bone, lung, liver, brain). The treatment of Stage TV breast cancer focuses on extending survival time and relieving symptoms. [0024] Based in part upon selection criteria set forth above, individuals having breast cancer can be selected for genetic studies. Also, individuals having no history of cancer or breast cancer often are selected for genetic studies. Other selection criteria can include: a tissue or fluid sample is derived from an individual characterized as Caucasian; the sample was derived from an individual of German paternal and maternal descent; the database included relevant phenotype information for the individual; case samples were derived from individuals diagnosed with breast cancer; control samples were derived from individuals free of cancer and no family history of breast cancer; and sufficient genomic DNA was extracted from each blood sample for all allelotyping and genotyping reactions performed during the study. Phenotype information included pre- or post-menopausal, familial predisposition, country or origin of mother and father, diagnosis with breast cancer (date of primary diagnosis, age of individual as of primary diagnosis, grade or stage of development, occurrence of metastases, e.g., lymph node metastases, organ metastases), condition of body tissue (skin tissue, breast tissue, ovary tissue, peritoneum tissue and myometrium), method of treatment (surgery, chemotherapy, hormone therapy, radiation therapy). [0025] Provided herein is a set of blood samples and a set of corresponding nucleic acid samples isolated from the blood samples, where the blood samples are donated from individuals diagnosed with breast cancer. The sample set often includes blood samples or nucleic acid samples from 100 or more, 150 or more, or 200 or more individuals having breast cancer, and sometimes from 250 or more, 300 or more, 400 or more, or 500 or more individuals. The individuals can have parents from any place of origin, and in an embodiment, the set of samples are extracted from individuals of German paternal and German maternal ancestry. The samples in each set may be selected based upon five or more criteria and/or phenotypes set forth above.

Polymoφhic Variants Associated with Breast Cancer [0026] A genetic analysis provided herein linked breast cancer with polymoφhic variants in the SPUVE, GRIN3A, PFTK1, SERPINA5, LOCI 15209 and HRMT1L3 regions ofthe human genome disclosed herein. As used herein, the term "polymoφhic site" refers to a region in a nucleic acid at which two or more alternative nucleotide sequences are observed in a significant number of nucleic acid samples from a population of individuals. A polymoφhic site may be a nucleotide sequence of two or more nucleotides, an inserted nucleotide or nucleotide sequence, a deleted nucleotide or nucleotide sequence, or a microsatelhte, for example. A polymoφhic site that is two or more nucleotides in length may be 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15 or more, 20 or more, 30 or more, 50 or more, 75 or more, 100 or more, 500 or more, or about 1000 nucleotides in length, where all or some ofthe nucleotide sequences differ within the region. A polymoφhic site is often one nucleotide in length, which is referred to herein as a "single nucleotide polymoφhism" or a "SNP." [0027] Where there are two, three, or four alternative nucleotide sequences at a polymoφhic site, each nucleotide sequence is referred to as a "polymoφhic variant" or "nucleic acid variant." Where two polymoφhic variants exist, for example, the polymoφhic variant represented in a minority of samples from a population is sometimes referred to as a "minor allele" and the polymoφhic variant that is more prevalently represented is sometimes referred to as a "major allele." Many organisms possess a copy of each chromosome (e.g., humans), and those individuals who possess two major alleles or two minor alleles are often referred to as being "homozygous" with respect to the polymoφhism, and those individuals who possess one major allele and one minor allele are normally referred to as being "heterozygous" with respect to the polymoφhism. Individuals who are homozygous with respect to one allele are sometimes predisposed to a different phenotype as compared to individuals who are heterozygous or homozygous with respect to another allele. [0028] Furthermore, a genotype or polymoφhic variant may be expressed in terms of a "haplotype," which as used herein refers to two or more polymoφhic variants occurring within genomic DNA in a group of individuals within a population. For example, two SNPs may exist within a gene where each SNP position includes a cytosine variation and an adenine variation. Certain individuals in a population may carry one allele (heterozygous) or two alleles (homozygous) having the gene with a cytosine at each SNP position. As the two cytosines corresponding to each SNP in the gene travel together on one or both alleles in these individuals, the individuals can be characterized as having a cytosine/cytosine haplotype with respect to the two SNPs in the gene. [0029] As used herein, the term "phenotype" refers to a trait which can be compared between individuals, such as presence or absence of a condition, a visually observable difference in appearance between individuals, metabolic variations, physiological variations, variations in the function of biological molecules, and the like. An example of a phenotype is occurrence of breast cancer. [0030] Researchers sometimes report a polymoφhic variant in a database without determining whether the variant is represented in a significant fraction of a population. Because a subset of these reported polymoφhic variants are not represented in a statistically significant portion ofthe population, some of them are sequencing errors and/or not biologically relevant. Thus, it is often not known whether a reported polymoφhic variant is statistically significant or biologically relevant until the presence ofthe variant is detected in a population of individuals and the frequency ofthe variant is determined. Methods for detecting a polymoφhic variant in a population are described herein, specifically in Example 2. A polymoφhic variant is statistically significant and often biologically relevant if it is represented in 5% or more of a population, sometimes 10% or more, 15% or more, or 20% or more of a population, and often 25% or more, 30% or more, 35% or more, 40% or more, 45% or more, or 50% or more of a population. [0031] A polymoφhic variant may be detected on either or both strands of a double-stranded nucleic acid. For example, a thymine at a particular position in SEQ ID NO: 1 can be reported as an adenine from the complementary strand. Also, a polymoφhic variant may be located within an intron or exon of a gene or within a portion of a regulatory region such as a promoter, a 5 ' untranslated region (UTR), a 3 ' UTR, and in DNA (e.g. , genomic DNA (gDNA) and complementary DNA (cDNA)), RNA (e.g., mRNA, tRNA, and rRNA), or a polypeptide. Polymoφhic variations may or may not result in detectable differences in gene expression, polypeptide structure, or polypeptide function. [0032] In the genetic analysis that associated breast cancer with the polymoφhic variants described hereafter, samples from individuals having breast cancer and individuals not having cancer were allelotyped and genotyped. The term "genotyped" as used herein refers to a process for determining a genotype of one or more individuals, where a "genotype" is a representation of one or more polymoφhic variants in a population. Genotypes may be expressed in terms of a "haplotype," which as used herein refers to two or more polymoφhic variants occurring within genomic DNA in a group of individuals within a population. For example, two SNPs may exist within a gene where each SNP position includes a cytosine variation and an adenine variation. Certain individuals in a population may carry one allele (heterozygous) or two alleles (homozygous) having the gene with a cytosine at each SNP position. As the two cytosines corresponding to each SNP in the gene travel together on one or both alleles in these individuals, the individuals can be characterized as having a cytosine/cytosine haplotype with respect to the two SNPs in the gene. [0033] It was determined that polymoφhic variations associated with an increased risk of breast cancer existed in SPUVE, GRIN3A, PFTK1, SERPINA5, LOCI 15209 or HRMT1L3 nucleotide sequences. Polymoφhic variants in and around the SPUVE, GRIN3A, PFTK1, SERPINA5, LOCI 15209 and HRMT1L3 loci were tested for association with breast cancer. In the SPUVE locus, these included polymoφhic variants at positions selected from the group consisting of rs2512980, rs2433444, rs2512990, rs4128368, rs744292, rs744293, rsl807014, rs2512992, rs2433453, rsl939117, rs2433452, rs2433451, rs750789, rs754490, rs2015747, rsl939115, rs2000537, rs2000538, rsl939116, rs2186616, rs2186617, rs2508423, rsl939118, rs2105587, rs872619, rs3809048, rs2511882, rsl939110, rsl954769, rs3781614, position 53700 of SEQ ID NO: 1, position 54089 of SEQ ID NO: 1, rs2155080, rs2155081, rs3177411, rsl939111, rsl939112, rsl939113, rsl939114, rs2511880, rsl892892, rsl892893, rs3016252, rs2511881, rs2005192, rs2011913, rs2555537, and rs2845686. Polymoφhic variants in a region spanning positions positions 62560 to 110963 in SEQ ID NO: 1 in particular were associated with an increased risk of breast cancer, including polymoφhic variants at positions rsl939115, rs2186617, rs2105587, rsl 939110, rsl 939114, and rs2511880. At these positions in SEQ ID NO: 1 , a thymine at position 1939115, a thymine at position 2186617, a thymine at position 2105587, a cytosine at position 1939110, a guanine at position 1939114, and a thymine at position 2511880 in particular were associated with risk of breast cancer. [0034] In the GRLN3A locus, these included polymoφhic variants at positions selected from the group consisting of rsl885977, rs2273976, rsl983812, rs3824473, rs3739722, rs942139, rsGRIN3A-AA, rs3739723, rs3739725, rsl323433, rsl323432, rs729688, rs2181562, rs2181561, rsl570514, rs2417290, rsl004362, rsl407875, rs2031202, rsl407874, rsl016428, and rsl016429. Polymoφhic variants in a region spanning positions 47793 to 50410 in SEQ ID NO: 2 in particular were associated with an increased risk of breast cancer, including a polymoφhic variant at position rsl323433. An adenine at position 50410 in SEQ ID NO: 2 in particular was associated with increased risk of breast cancer. [0035] In the PFTK1 locus, these included polymoφhic variants at positions selected from the group consisting of rs6465273, rs994511, rsl 858767, position 122804 in SEQ ID NO:3, rsl079528, rsl079527, rsl557651, rsl016963, rs756741, rs756740, rsl557654, rsl005875, rsl005874, rs2374358, rs2213982, rs2888811, rs3802016, rs3802017, rs2213981, rs2188242, rs2213980, rs3802019, rs3802020, rs3802021, rs2188241, rs3808223, rs2040520, rs718313, rsl858809, rs3824036, rs3808226, rs3808227, rsl989791, rs3824037, rs3779554, rs2188240, rs2188239, rsl 110457, rs3779556, rsl 110456, rs3779558, rs3729626, rs721175, rs2040519, rs2040518, rs3808229, rs3808230, rs3808231, rs3824038, rsl858808, rsl858807, and position 259268 in SEQ ID NO:3. Polymoφhic variants in a region spanning positions 151896 to 259268 in SEQ ID NO: 3 in particular were associated with an increased risk of breast cancer, including polymoφhic variants at positions rs756740, rsl557654, rs2188242, rs2040520, rs3824036, rsl989791, rs721175, and position 259268 in SEQ ID NO: 3. At these positions in SEQ ID NO: 3, a cytosine at position 151896, an adenine at position 152217, an adenine at position 156067, a cytosine at position 160456, an adenine at position 167194, an adenine at position 171323, a cytosine at position 185032, and a cytosine at position 259268 in particular were associated with an increased risk of breast cancer. [0036] In the SERPINA5 locus, these included polymoφhic variants at positions selected from the group consisting of rs746386, rs744589, rs2180872, rs2093265, rs2180873, rs2896287, rs2402477, rs2402478, rs2402479, rs2092712, rsl243280, rs910348, rs910349, rs882732, rs882731, rs910352, rs910353, rs910354, rs3762123, rs879362, rs3762122, rs5508, rs2144077, rs2284656, rs941755, rs2093266, rsl005348, rs5510, rs5511, rs3827893, rs2068790, rs2070777, rs5512, rsl007149, rsl998243, rs910342, rsl004958, rs761536, rs2144075, rsl955652, rsl955653, rsl885135, rsl955655, rsl955656, rsl475937, rsl475938, rsl983657, position 40863 in SEQ ID

NO: 4, position 40899 in SEQ ID NO: 4, rs2144076, rs8019792, rs8020223, rs8019810, rs2854946, rs885786, rs2747116, rs2747117, rs2854947, rs2069957, rs2069958, rs2069959, rs2854948, rs2069962, rs2069963, rs2069965, rs2069966, rs2069967, rs2069968, rs2069969, rs2069970, rs2069998, rs2069971, rs2069972, rs2069973, rs2069974, rs3177817, rs2069975, rs6113, rs6118, rs6115, rs2069976, rs2069999, rs6120, rs6112, rs2069977, rs2069978, rs2069979, rs2070004, rs2069982, rs2069983, rs2066969, rs2069984, rs6114, rs2069985, rs2069986, rs3177818, rs6107, rs2069987, rs2982746, rs2982747, rs2069988, rs2069989, rs6109, rs6116, rs2069990, rs6108, rs2070005, rs2067060, rs2069991, rs938, rsl050013, rs2069992, rs9113, rs2069993, rs7069, rs7070, rs2854941, rs2069994, rs2069995, rs2069996, rs2069997, rs2854942, rs2747118, rs2854943, rs2854944, rsl 884077, rsl 884078, rsl 884079, rsl 884081, rs742894, rs742895, rs2402480, rs2402481, position 56372 in SEQ ID NO: 4, rsl 1160194, rs8009357, rs734475, rs957620, rs926788, rs926790, rsl955658, rsl004761, rsl884082, rs4934, rs2896288, rs2268334, rs2268335, rs2268336, rs2268337, rsl7473, rs742896, rs2402482, rs733815, rs910350, rs2284657, rs2284658, rs742897, rsl065623, rs3180112, rs742898, rsll57271, rsl950298, rsl955659, rsl 154824, rsl 154825, rs979048, rsl 950300, rs997280, and rs990777. Polymoφhic variants in a region spanning positions 23143 to 75716 in SEQ ID NO: 4 in particular were associated with an increased risk of breast cancer, including polymoφhic variants at positions rs2069990, rs2854943, rsl004761, and rs2268335. At these positions in SEQ ID NO: 4, a guanine at position 51905, a cytosine at position 53688, a guanine at position 69502, and a cytosine at position 75716 in particular were associated with an increased risk of breast cancer. [0037] In the LOCI 15209 locus, these included polymoφhic variants at positions selected from the group consisting of rs706460, rs706461, rs697587, rs706462, rs706463, rs644319, rs642657, rs706464, rs630638, rs338254, rs338253, rs338252, rs338251, rs697588, rs338250, rs338249, rs338248, rs697589, rs338247, rs696297, rs697590, rs338245, rs338243, rs822064, rs338242, rs338241, rs338240, rs338239, rs338238, rs822061, rs697592, rs338237, rs338235, rs338234, rs338232, rs338231, rs2153731, rs338230, rs338229, rs338228, position 24422 of SEQ D NO: 5, rs697593, rs338225, rs338226, rs338227, rsl93133, rsl84617, rsl93134, rs618043, rs618932, rs697594, rs697595, rsl228818, rsl503646, rsl983078, rs2062833, rsl394000, rs2271004, rs2271005, rsl503648, rsl847351, rsl388981, rsl388980, position 77510 of SEQ ID

NO: 5, position 82668 of SEQ ID NO: 5, rs902925, position 83005 of SEQ ID NO: 5, position

83031 of SEQ ID NO: 5, rs2406786, rs3813996, rs905567, rs2087799, rs2406785, rs2406784, rs4316384, rs4399185, rs2406783, rsl799705, rsl775002, rs644928, rs488606, rs530095, rs593279, rs532134, rs564252, rs565008, rs565954, rs567787, rs673276, rs672859, rs671830, rs511687, rs518070, rsl627332, rs542727, rs544596, rs627218, rs627633, and rs546271. Polymoφhic variants in a region spanning positions 14202 to 99855 in SEQ ID NO: 5 in particular were associated with an increased risk of breast cancer, including polymoφhic variants at positions rs338228, rs338225, rs, rs2271005, rsl847351, position 77510 of SEQ ID NO: 5, position 83031 of SEQ ID NO: 5, rs3813996, rs905567, rs2406785, rs2406784, rsl775002, rs565954, rs671830, and rs518070. Of these positions in SEQ ID NO: 5, a guanine at position 20848, an adenine at position 26704, a guanine at position 74223, a thymine at position 75505, an adenine at position 77510, an adenine at position 83031, a guanine at position 88996, an adenine at position 89391, an adenine at position 89803, a thymine at position 89805, an adenine at position 94418, a guanine at position 96890, a guanine at position 97575, and a thymine at position 99131 in particular were associated with an increased risk of breast cancer. [0038] In the HRMT1L3 locus, these included polymoφhic variants at positions selected from the group consisting of rs2878580, rs2335988, rs2335990, position 4012 of SEQ ID NO: 6, position 4154 of SEQ ID NO: 6, rs731577, rs2191204, rs3741939, rs3741938, rs3759362, rs378276 , rs3782760, rs3782759, rs3782758, rs3782756, rs2191205, rs3741937, rs3782755, rs878771, rs876593, rs3825340, position 39171 of SEQ ID NO: 6, position 39526 of SEQ ID NO: 6, rs3782753, rs3782752, rs2191216, rs3782751, rs3782750, rs3782749, rs3782748, rsl860450, rsl860449, rs3782747, rs3825339, rs3741936, rs917602, rs917601, rs917600, rs2191215, rs3782746, rs3782745, rs3782744, rsl860451, rs758637, rs917564, rs3741935, rsl029766, and rs887303. Polymoφhic variants in a region spanning positions 4154 to 80061 in SEQ ID NO: 6 in particular were associated with an increased risk of breast cancer, including polymoφhic variants at position 4154 of SEQ ID NO: 6, rs2191216, rs917602, and rs917564. Of these positions in SEQ ID NO: 6, an adenine at position 4154, a thymine at position 47415, a thymine at position 56284, a thymine at position 76648 in particular were associated with increased risk of breast cancer. [0039] Based in part upon analyses summarized in Figures 1A-1G, regions with significant association have been identified in SPUVE, GRIN3A, PFTK1, SERPINA5, LOCI 15209 or HRMT1L3 regions associated with increased risk of breast cancer. Any polymoφhic variants associated with an increased risk of breast cancer in a region of significant association can be utilized for embodiments described herein. The following reports such a region, where "begin" and "end" designate the boundaries ofthe region according to chromosome positions within NCBI's Genome Build 34. For example, a region of association spanning positions 86230463 to 86253960 in a SPUVE locus was significantly associated with an increased risk of breast cancer.

Additional Polymorphic Variants Associated with Breast Cancer [0040] Also provided is a method for identifying polymoφhic variants proximal to an incident, founder polymoφhic variant associated with breast cancer. Thus, featured herein are methods for identifying a polymoφhic variation associated with breast cancer that is proximal to an incident polymoφhic variation associated with breast cancer, which comprises identifying a polymoφhic variant proximal to the incident polymoφhic variant associated with breast cancer, where the incident polymoφhic variant is in a nucleotide sequence set forth in SEQ ID NO: 1-6. The nucleotide sequence often comprises a polynucleotide sequence selected from the group consisting "^• of (a) a nucleotide sequence set forth in SEQ ID NO: 1-6; (b) a nucleotide sequence which encodes a polypeptide having an amino acid sequence encoded by a nucleotide sequence in SEQ ID NO: 1- 6; (c) a nucleotide sequence which encodes a polypeptide that is 90% or more identical to an amino acid sequence encoded by a nucleotide sequence in SEQ ID NO: 1-6 or a nucleotide sequence about 90% or more identical to the nucleotide sequence set forth in SEQ ID NO: 1-6; and (d) a fragment of a nucleotide sequence of (a), (b), or (c), often a fragment that includes a polymoφhic site associated with breast cancer. The presence or absence of an association ofthe proximal polymoφhic variant with breast cancer then is determined using a known association method, such as a method described in the Examples hereafter. In an embodiment, the incident polymoφhic variant is described in SEQ ID NO: 1-6. In another embodiment, the proximal polymoφhic variant identified sometimes is a publicly disclosed polymoφhic variant, which for example, sometimes is published in a publicly available database. In other embodiments, the polymoφhic variant identified is not publicly disclosed and is discovered using a known method, including, but not limited to, sequencing a region surrounding the incident polymoφhic variant in a group of nucleic acid samples. Thus, multiple polymorphic variants proximal to an incident polymoφhic variant are associated with breast cancer using this method. [0041] The proximal polymorphic variant often is identified in a region surrounding the incident polymoφhic variant. In certain embodiments, this surrounding region is about 50 kb flanking the first polymoφhic variant (e.g. about 50 kb 5' ofthe first polymoφhic variant and about 50 kb 3' ofthe first polymorphic variant), and the region sometimes is composed of shorter flanking sequences, such as flanking sequences of about 40 kb, about 30 kb, about 25 kb, about 20 kb, about 15 kb, about 10 kb, about 7 kb, about 5 kb, or about 2 kb 5' and 3' ofthe incident polymoφhic variant. In other embodiments, the region is composed of longer flanking sequences, such as flanking sequences of about 55 kb, about 60 kb, about 65 kb, about 70 kb, about 75 kb, about 80 kb, about 85 kb, about 90 kb, about 95 kb, or about 100 kb 5' and 3' ofthe incident polymoφhic variant. [0042] In certain embodiments, polymoφhic variants associated with breast cancer are identified iteratively. For example, a first proximal polymoφhic variant is associated with breast cancer using the methods described above and then another polymoφhic variant proximal to the first proximal polymoφhic variant is identified (e.g., publicly disclosed or discovered) and the presence or absence of an association of one or more other polymoφhic variants proximal to the first proximal polymoφhic variant with breast cancer is determined. [0043] The methods described herein are useful for identifying or discovering additional polymoφhic variants that may be used to further characterize a gene, region or loci associated with a condition, a disease (e.g., breast cancer), or a disorder. For example, allelotyping or genotyping data from the additional polymoφhic variants may be used to identify a functional mutation or a region of linkage disequilibrium. [0044] In certain embodiments, polymoφhic variants identified or discovered within a region comprising the first polymoφhic variant associated with breast cancer are genotyped using the genetic methods and sample selection techniques described herein, and it can be determined whether those polymoφhic variants are in linkage disequilibrium with the first polymoφhic variant. The size ofthe region in linkage disequilibrium with the first polymoφhic variant also can be assessed using these genotyping methods. Thus, provided herein are methods for determining whether a polymoφhic variant is in linkage disequilibrium with a first polymoφhic variant associated with breast cancer, and such information can be used in prognosis methods described herein.

Isolated SPUVE. GRIN3A. PFTK1. SERPINA5. LOCH 5209 or HRMT1L3 Nucleic Acids [0045] Featured herein are isolated SPUVE, GRIN3A, PFTK1, SERPINA5, LOCI 15209 or

HRMT1L3 nucleic acids, which include the nucleic acid having the nucleotide sequence of SEQ ID

NO: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 or 12, nucleic acid variants, and substantially identical nucleic acids ofthe foregoing. Nucleotide sequences ofthe SPUVE, GRLN3A, PFTK1, SERPINA5,

LOCI 15209 or HRMT1L3 nucleic acids sometimes are referred to herein as "SPUVE, GRIN3A,

PFTK1, SERPINA5, LOCI 15209 or HRMT1L3 nucleotide sequences." A "SPUVE, GRIN3A,

PFTK1, SERPINA5, LOCI 15209 or HRMT1L3 nucleic acid variant" refers to one allele that may have one or more different polymoφhic variations as compared to another allele in another subject or the same subject. A polymoφbic variation in the SPUVE, GRIN3A, PFTK1, SERPINA5, LOCI 15209 or HRMT1L3 nucleic acid variant may be represented on one or both strands in a double-stranded nucleic acid or on one chromosomal complement (heterozygous) or both chromosomal complements (homozygous). [0046] As used herein, the term "nucleic acid" includes DNA molecules (e.g., a complementary DNA (cDNA) and genomic DNA (gDNA)) and RNA molecules (e.g., mRNA, rRNA, and tRNA) and analogs of DNA or RNA, for example, by use of nucleotide analogs. The nucleic acid molecule can be single-stranded and it is often double-stranded. The term "isolated or purified nucleic acid" refers to nucleic acids that are separated from other nucleic acids present in the natural source ofthe nucleic acid. For example, with regard to genomic DNA, the term "isolated" includes nucleic acids which are separated from the chromosome with which the genomic DNA is naturally associated. An "isolated" nucleic acid is often free of sequences which naturally flank the nucleic acid (i.e., sequences located at the 5' and/or 3' ends ofthe nucleic acid) in the genomic DNA ofthe organism from which the nucleic acid is derived. For example, in various embodiments, the isolated nucleic acid molecule can contain less than about 5 kb, 4 kb, 3 kb, 2 kb, 1 kb, 0.5 kb or 0.1 kb of 5' and/or 3' nucleotide sequences which flank the nucleic acid molecule in genomic DNA ofthe cell from which the nucleic acid is derived. Moreover, an "isolated" nucleic acid molecule, such as a cDNA molecule, can be substantially free of other cellular material, or culture medium when produced by recombinant techniques, or substantially free of chemical precursors or other chemicals when chemically synthesized. As used herein, the term "SPUVE, GRIN3A, PFTK1, SERPINA5, LOCI 15209 oτHRMTlL3 gene" refers to a nucleotide sequence that encodes a SPUVE, GRIN3A, PFTK1, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide. [0047] Also included herein are nucleic acid fragments. These fragments typically are a nucleotide sequence identical to a nucleotide sequence in SEQ ID NO: 1-12, a nucleotide sequence substantially identical to a nucleotide sequence in SEQ ID NO: 1-12, or a nucleotide sequence that is complementary to the foregoing. The nucleic acid fragment may be identical, substantially identical or homologous to a nucleotide sequence in an exon or an intron in SEQ ED NO: 1-6, and may encode a domain or part of a domain or motif of a SPUVE, GRIN3A, PFTK1, SERPINA5,

LOCH 5209 or HRMT1L3 polypeptide, sometimes the domains set forth hereafter. Sometimes, the fragment comprises the polymoφhic variation described herein as being associated with breast cancer. The nucleic acid fragment sometimes is 50, 100, or 200 or fewer base pairs in length, and is sometimes about 300, 400, 500, 600, 700, 800, 900, 1000, 1100, 1200, 1300, 1400, 1500, 1600,

1700, 1800, 1900, 2000, 2100, 2200, 2300, 2400, 2500, 2600, 2700, 2800, 2900, 3000, 3100, 3200,

3300, 3400, 3500, 3600, 3800, 4000, 5000, 6000, 7000, 8000, 9000, 10000, 15000, 20000, 30000,

40000, 50000, 60000, 70000, 80000, 90000, 100000, 110000, 120000, 130000, 140000, 150000 or

160000 base pairs in length. A nucleic acid fragment complementary to a nucleotide sequence identical or substantially identical to the nucleotide sequence of SEQ ED NO: 1-12 and hybridizes to such a nucleotide sequence under stringent conditions often is referred to as a "probe." Nucleic acid fragments often include one or more polymoφhic sites, or sometimes have an end that is adjacent to a polymoφhic site as described hereafter. [0048] An example of a nucleic acid fragment is an oligonucleotide. As used herein, the term "oligonucleotide" refers to a nucleic acid comprising about 8 to about 50 covalently linked nucleotides, often comprising from about 8 to about 35 nucleotides, and more often from about 10 to about 25 nucleotides. The backbone and nucleotides within an oligonucleotide may be the same as those of naturally occurring nucleic acids, or analogs or derivatives of naturally occurring nucleic acids, provided that oligonucleotides having such analogs or derivatives retain the ability to hybridize specifically to a nucleic acid comprising a targeted polymoφhism. Oligonucleotides described herein may be used as hybridization probes or as components of prognostic or diagnostic assays, for example, as described herein. [0049] Oligonucleotides are typically synthesized using standard methods and equipment, such as the ABI 3900 High Throughput DNA Synthesizer and the EXPEDITE™ 8909 Nucleic Acid Synthesizer, both of which are available from Applied Biosystems (Foster City, CA). Analogs and derivatives are exemplified in U.S. Pat. Nos. 4,469,863; 5,536,821; 5,541,306; 5,637,683; 5,637,684; 5,700,922; 5,717,083; 5,719,262; 5,739,308; 5,773,601; 5,886,165; 5,929,226; 5,977,296; 6,140,482; WO 00/56746; WO 01/14398, and related publications. Methods for synthesizing oligonucleotides comprising such analogs or derivatives are disclosed, for example, in the patent publications cited above and in U.S. Pat. Nos. 5,614,622; 5,739,314; 5,955,599; 5,962,674; 6,117,992; in WO 00/75372; and in related publications. [0050] Oligonucleotides also may be linked to a second moiety. The second moiety may be an additional nucleotide sequence such as a tail sequence (e.g., a polyadenosine tail), an adapter sequence (e.g., phage Ml 3 universal tail sequence), and others. Alternatively, the second moiety may be a non-nucleotide moiety such as a moiety which facilitates linkage to a solid support or a label to facilitate detection ofthe oligonucleotide. Such labels include, without limitation, a radioactive label, a fluorescent label, a chemiluminescent label, a paramagnetic label, and the like. The second moiety may be attached to any position ofthe oligonucleotide, provided the oligonucleotide can hybridize to the nucleic acid comprising the polymoφhism.

Uses for Nucleic Acid Sequences [0051] Nucleic acid coding sequences depicted in SEQ ED NO: 1-12 may be used for diagnostic puφoses for detection and control of polypeptide expression. Also, included herein are oligonucleotide sequences such as antisense RNA, small-interfering RNA (siRNA) and DNA molecules and ribozymes that function to inhibit translation of a polypeptide. Antisense techniques and RNA interference techniques are known in the art and are described herein. [0052] Ribozymes are enzymatic RNA molecules capable of catalyzing the specific cleavage of RNA. The mechanism of ribozyme action involves sequence specific hybridization ofthe ribozyme molecule to complementary target RNA, followed by a endonucleolytic cleavage. Ribozymes may be engineered hammerhead motif ribozyme molecules that specifically and efficiently catalyze endonucleolytic cleavage of RNA sequences corresponding to or complementary to the nucleotide sequences set forth in SEQ ED NO: 1-12. Specific ribozyme cleavage sites within any potential RNA target are initially identified by scanning the target molecule for ribozyme cleavage sites which include the following sequences, GUA, GUU and GUC. Once identified, short RNA sequences of between fifteen (15) and twenty (20) ribonucleotides corresponding to the region ofthe target gene containing the cleavage site may be evaluated for predicted structural features such as secondary structure that may render the oligonucleotide sequence unsuitable. The suitability of candidate targets may also be evaluated by testing their accessibility to hybridization with complementary oligonucleotides, using ribonuclease protection assays. [0053] Antisense RNA and DNA molecules, siRNA and ribozymes may be prepared by any method known in the art for the synthesis of RNA molecules. These include techniques for chemically synthesizing oligodeoxyribonucleotides well known in the art such as solid phase phosphoramidite chemical synthesis. Alternatively, RNA molecules may be generated by in vitro and in vivo transcription of DNA sequences encoding the antisense RNA molecule. Such DNA sequences may be incoφorated into a wide variety of vectors which incoφorate suitable RNA polymerase promoters such as the T7 or SP6 polymerase promoters. Alternatively, antisense cDNA constructs that synthesize antisense RNA constitutively or inducibly, depending on the promoter used, can be introduced stably into cell lines. [0054] DNA encoding a polypeptide also may have a number of uses for the diagnosis of diseases, including breast cancer, resulting from aberrant expression of a target gene described herein. For example, the nucleic acid sequence may be used in hybridization assays of biopsies or autopsies to diagnose abnormalities of expression or function (e.g., Southern or Northern blot analysis, in situ hybridization assays). [0055] In addition, the expression of a polypeptide during embryonic development may also be determined using nucleic acid encoding the polypeptide. As addressed, infra, production of functionally impaired polypeptide can be the cause of various disease states, such as breast cancer.

In situ hybridizations using polynucleotide probes may be employed to predict problems related to breast cancer. Further, as indicated, infra, administration of human active polypeptide, recombinantiy produced as described herein, may be used to treat disease states related to functionally impaired polypeptide. Alternatively, gene therapy approaches may be employed to remedy deficiencies of functional polypeptide or to replace or compete with dysfunctional polypeptide.

Expression Vectors. Host Cells, and Genetically Engineered Cells [0056] Provided herein are nucleic acid vectors, often expression vectors, which contain a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 nucleic acid. As used herein, the term "vector" refers to a nucleic acid molecule capable of transporting another nucleic acid to which it has been linked and can include a plasmid, cosmid, or viral vector. The vector can be capable of autonomous replication or it can integrate into a host DNA. Viral vectors may include replication defective retroviruses, adenoviruses and adeno-associated viruses for example. [0057] A vector can include a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 nucleic acid in a form suitable for expression ofthe nucleic acid in a host cell. The recombinant expression vector typically includes one or more regulatory sequences operatively linked to the nucleic acid sequence to be expressed. The term "regulatory sequence" includes promoters, enhancers and other expression control elements (e.g., polyadenylation signals). Regulatory sequences include those that direct constitutive expression of a nucleotide sequence, as well as tissue-specific regulatory and/or inducible sequences. The design ofthe expression vector can depend on such factors as the choice ofthe host cell to be transformed, the level of expression of polypeptide desired, and the like. Expression vectors can be introduced into host cells to produce SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptides, including fusion polypeptides, encoded by SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 nucleic acids. [0058] Recombinant expression vectors can be designed for expression of SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptides in prokaryotic or eukaryotic cells. For example, SPUVE, GRIN3A, PFTKl, SERPINA5, LOCH 5209 or HRMT1L3 polypeptides can be expressed in E. coli, insect cells (e.g., using baculovirus expression vectors), yeast cells, or mammalian cells. Suitable host cells are discussed further in Goeddel, Gene Expression Technology: Methods in Enzymology 185, Academic Press, San Diego, CA (1990). Alternatively, the recombinant expression vector can be transcribed and translated in vitro, for example using T7 promoter regulatory sequences and T7 polymerase. [0059] Expression of polypeptides in prokaryotes is most often carried out in E. coli with vectors containing constitutive or inducible promoters directing the expression of either fusion or non-fusion polypeptides. Fusion vectors add a number of amino acids to a polypeptide encoded therein, usually to the amino terminus ofthe recombinant polypeptide. Such fusion vectors typically serve three puφoses: 1) to increase expression of recombinant polypeptide; 2) to increase the solubility ofthe recombinant polypeptide; and 3) to aid in the purification ofthe recombinant polypeptide by acting as a ligand in affinity purification. Often, a proteolytic cleavage site is introduced at the junction ofthe fusion moiety and the recombinant polypeptide to enable separation ofthe recombinant polypeptide from the fusion moiety subsequent to purification ofthe fusion polypeptide. Such enzymes, and their cognate recognition sequences, include Factor Xa, thrombin and enterokinase. Typical fusion expression vectors include pGEX (Pharmacia Biotech Inc; Smith & Johnson, Gene 67: 31-40 (1988)), pMAL (New England Biolabs, Beverly, MA) and ρRLT5 (Pharmacia, Piscataway, NJ) which fuse glutathione S-transferase (GST), maltose E binding polypeptide, or polypeptide A, respectively, to the target recombinant polypeptide. [0060] Purified fusion polypeptides can be used in screening assays and to generate antibodies specific for SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptides. In a therapeutic embodiment, fusion polypeptide expressed in a retroviral expression vector is used to infect bone marrow cells that are subsequently transplanted into irradiated recipients. The pathology ofthe subject recipient is then examined after sufficient time has passed (e.g., six (6) weeks). [0061] Expressing the polypeptide in host bacteria with an impaired capacity to proteolytically cleave the recombinant polypeptide is often used to maximize recombinant polypeptide expression (Gottesman, S., Gene Expression Technology: Methods in Enzymology, Academic Press, San Diego, California 185: 119-128 (1990)). Another strategy is to alter the nucleotide sequence ofthe nucleic acid to be inserted into an expression vector so that the individual codons for each amino acid are those preferentially utilized in E. coli (Wada et al., Nucleic Acids Res. 20: 2111-2118 (1992)). Such alteration of nucleotide sequences can be carried out by standard DNA synthesis techniques. [0062] When used in mammalian cells, the expression vector's control functions are often provided by viral regulatory elements. For example, commonly used promoters are derived from polyoma, Adenovirus 2, cytomegalovirus and Simian Virus 40. Recombinant mammalian expression vectors are often capable of directing expression ofthe nucleic acid in a particular cell type (e.g., tissue-specific regulatory elements are used to express the nucleic acid). Non-limiting examples of suitable tissue-specific promoters include an albumin promoter (Uver-specific; Pinkert et al., Genes Dev. 1: 268-277 (1987)), lymphoid-specific promoters (Calame & Eaton, Adv.

Immunol. 43: 235-275 (1988)), promoters of T cell receptors (Winoto & Baltimore, EMBO J. 8:

729-733 (1989)) promoters of immunoglobulins (Banerji et al., Cell 33: 729-740 (1983); Queen &

Baltimore, Cell 33: 741-748 (1983)), neuron-specific promoters (e.g., the neurofilament promoter;

Byrne & Ruddle, Proc. Natl. Acad. Sci. USA 86: 5473-5477 (1989)), pancreas-specific promoters

(Edlund et al., Science 230: 912-916 (1985)), and mammary gland-specific promoters (e.g., milk whey promoter; U.S. Patent No. 4,873,316 and European Application Publication No. 264,166). Developmentally-regulated promoters are sometimes utilized, for example, the murine hox promoters (Kessel & Grass, Science 249: 374-379 (1990)) and the a-fetopolypeptide promoter (Campes & Tilghman, Genes Dev. 3: 537-546 (1989)). [0063] A SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 nucleic acid may also be cloned into an expression vector in an antisense orientation. Regulatory sequences (e.g., viral promoters and/or enhancers) operatively linked to a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 nucleic acid cloned in the antisense orientation can be chosen for directing constitutive, tissue specific or cell type specific expression of antisense RNA in a variety of cell types. Antisense expression vectors can be in the form of a recombinant plasmid, phagemid or attenuated virus. For a discussion ofthe regulation of gene expression using antisense genes see Weintraub et al., Antisense RNA as a molecular tool for genetic analysis, Reviews - Trends in Genetics, Vol. 1(1) (1986). [0064] Also provided herein are host cells that include a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 nucleic acid within a recombinant expression vector or SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 nucleic acid sequence fragments which allow it to homologously recombine into a specific site ofthe host cell genome. The terms "host cell" and "recombinant host cell" are used interchangeably herein. Such terms refer not only to the particular subject cell but rather also to the progeny or potential progeny of such a cell. Because certain modifications may occur in succeeding generations due to either mutation or environmental influences, such progeny may not, in fact, be identical to the parent cell, but are still included within the scope ofthe term as used herein. A host cell can be any prokaryotic or eukaryotic cell. For example, a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide can be expressed in bacterial cells such as E. coli, insect cells, yeast or mammalian cells (such as Chinese hamster ovary cells (CHO) or COS cells). Other suitable host cells are known to those skilled in the art. [0065] Vectors can be introduced into host cells via conventional transformation or transfection techniques. As used herein, the terms "transformation" and "transfection" are intended to refer to a variety of art-recognized techniques for introducing foreign nucleic acid (e.g., DNA) into a host cell, including calcium phosphate or calcium chloride co-precipitation, transduction/infection, DEAE-dextran-mediated transfection, lipofection, or electroporation. [0066] A host cell provided herein can be used to produce (i.e., express) a SPUVE, GRIN3A,

PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide. Accordingly, further provided are methods for producing a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCH 5209 or HRMT1L3 polypeptide using the host cells described herein. In one embodiment, the method includes culturing host cells into which a recombinant expression vector encoding a SPUVE, GRIN3A,

PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide has been introduced in a suitable medium such that a SPUVE, GRIN3A, PFTKl, SERPLNA5, LOCI 15209 or HRMT1L3 polypeptide is produced. In another embodiment, the method further includes isolating a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCH 5209 or HRMT1L3 polypeptide from the medium or the host cell. [0067] Also provided are cells or purified preparations of cells which include a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 transgene, or which otherwise misexpress SPUVE, GRIN3A, PFTKl, SERPINA5, LOCH 5209 or HRMT1L3 polypeptide. Cell preparations can consist of human or non-human cells, e.g., rodent cells, e.g., mouse or rat cells, rabbit cells, or pig cells. In certain embodiments, the cell or cells include a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 transgene (e.g., a heterologous form of a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 such as a human gene expressed in non-human cells). The SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 transgene can be misexpressed, e.g., overexpressed or underexpressed. En other embodiments, the cell or cells include a gene which misexpress an endogenous SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide (e.g., expression of a gene is disrupted, also known as a knockout). Such cells can serve as a model for studying disorders which are related to mutated or mis-expressed SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 alleles or for use in drug screening. Also provided are human cells (e.g., a hematopoietic stem cells) transformed with a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 nucleic acid. [0068] Also provided are cells or a purified preparation thereof (e.g., human cells) in which an endogenous SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 nucleic acid is under the control of a regulatory sequence that does not normally control the expression ofthe endogenous SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 gene. The expression characteristics of an endogenous gene within a cell (e.g., a cell line or microorganism) can be modified by inserting a heterologous DNA regulatory element into the genome ofthe cell such that the inserted regulatory element is operably linked to the endogenous SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 gene. For example, an endogenous SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 gene (e.g, a gene which is "transcriptionally silent," not normally expressed, or expressed only at very low levels) may be activated by inserting a regulatory element which is capable of promoting the expression of a normally expressed gene product in that cell. Techniques such as targeted homologous recombinations, can be used to insert the heterologous DNA as described in, e.g, Chappel, US 5,272,071; WO 91/06667, published on May 16, 1991.

Transgenic Animals [0069] Non-human transgenic animals that express a heterologous SPUVE, GRIN3A, PFTKl,

SERPINA5, LOCI 15209 or HRMT1L3 polypeptide (e.g, expressed from a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 nucleic acid isolated from another organism) can be generated. Such animals are useful for studying the function and/or activity of a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide and for identifying and/or evaluating modulators of SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 nucleic acid and SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide activity. As used herein, a "transgenic animal" is a non-human animal such as a mammal (e.g, a non-human primate such as chimpanzee, baboon, or macaque; an ungulate such as an equine, bovine, or caprine; or a rodent such as a rat, a mouse, or an Israeli sand rat), a bird (e.g, a chicken or a turkey), an amphibian (e.g, a frog, salamander, or newt), or an insect (e.g, Drosophila melanogaster), in which one or more ofthe cells ofthe animal includes a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 transgene. A transgene is exogenous DNA or a rearrangement (e.g, a deletion of endogenous chromosomal DNA) that is often integrated into or occurs in the genome of cells in a transgenic animal. A transgene can direct expression of an encoded gene product in one or more cell types or tissues ofthe transgenic animal, and other transgenes can reduce expression (e.g, a knockout). Thus, a transgenic animal can be one in which an endogenous SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 gene has been altered by homologous recombination between the endogenous gene and an exogenous DNA molecule introduced into a cell ofthe animal (e.g, an embryonic cell ofthe animal) prior to development ofthe animal. [0070] Intronic sequences and polyadenylation signals can also be included in the transgene to increase expression efficiency ofthe transgene. One or more tissue-specific regulatory sequences can be operably linked to a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 transgene to direct expression of a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide to particular cells. A transgenic founder animal can be identified based upon the presence of a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 transgene in its genome and/or expression of SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 mRNA in tissues or cells ofthe animals. A transgenic founder animal can then be used to breed additional animals carrying the transgene. Moreover, transgenic animals carrying a transgene encoding a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide can further be bred to other transgenic animals carrying other transgenes. [0071] SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptides can be expressed in transgenic animals or plants by introducing, for example, a nucleic acid encoding the polypeptide into the genome of an animal. In certain embodiments the nucleic acid is placed under the control of a tissue specific promoter, e.g, a milk or egg specific promoter, and recovered from the milk or eggs produced by the animal. Also included is a population of cells from a transgenic animal. SPUVE. GRIN3A. PFTKl. SERPINA5. LOCI 15209 and HRMT1L3 Polypeptides [0072] Featured herein are isolated SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or

HRMT1L3 polypeptides, which include polypeptides having amino acid sequences set forth in SEQ

ED NO: 13-18, and substantially identical polypeptides thereof. Such polypeptides sometimes are proteins or peptides. A SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide is a polypeptide encoded by a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or

HRMT1L3 nucleic acid, where one nucleic acid can encode one or more different polypeptides. An

"isolated" or "purified" polypeptide or protein is substantially free of cellular material or other contaminating proteins from the cell or tissue source from which the protein is derived, or substantially free from chemical precursors or other chemicals when chemically synthesized. In one embodiment, the language "substantially free" means preparation of a SPUVE, GRIN3A,

PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide or SPUVE, GRIN3A, PFTKl,

SERPINA5, LOCI 15209 or HRMT1L3 polypeptide variant having less than about 30%, 20%, 10% and sometimes 5% (by dry weight), of no -SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or

HRMT1L3 polypeptide (also referred to herein as a "contaminating protein"), or of chemical precursors or non-SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 chemicals.

When the SPUVE, GRIN3A, PFTKl, SERPINA5, LOCH 5209 or HRMT1L3 polypeptide or a biologically active portion thereof is recombinantiy produced, it is also often substantially free of culture medium, specifically, where culture medium represents less than about 20%, sometimes less than about 10%, and often less than about 5% ofthe volume ofthe polypeptide preparation.

Isolated or purified SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide preparations are sometimes 0.01 milligrams or more or 0.1 milligrams or more, and often 1.0 milligrams or more and 10 milligrams or more in dry weight. En specific embodiments, a polypeptide comprises a leucine at amino acid position 105 in SEQ ED NO: 16, a histidine at a position corresponding to the amino acid at position 36 in SEQ ED NO: 13, a serine at a position corresponding to the amino acid at position 166 in SEQ ED NO: 13, a glycine at a position corresponding to the amino acid at position 217 in SEQ ED NO: 16, a proline at a position corresponding to an amino acid at position 121, 246, 252, 198 and/or 115 in SEQ ED NO: 16, an arginine at a position corresponding to the amino acid at position 335 in SEQ ED NO: 16, or an isoleucine corresponding to the amino acid at position 329 in SEQ ED NO: 17. [0073] In another aspect, featured herein are SPUVE, GRIN3A, PFTKl, SERPINA5,

LOCI 15209 or HRMT1L3 polypeptides and biologically active or antigenic fragments thereof that are useful as reagents or targets in assays applicable to prevention, treatment or diagnosis of breast cancer. In another embodiment, provided herein are SPUVE, GRIN3A, PFTKl, SERPINA5,

LOCI 15209 or HRMT1L3 polypeptides having a SPUVE, GRIN3A, PFTKl, SERPINA5,

LOCI 15209 or HRMT1L3 activity or activities. [0074] Further included herein are SPUVE, GRIN3A, PFTKl, SERPMA5, LOCI 15209 or HRMT1L3 polypeptide fragments. The polypeptide fragment may be a domain or part of a domain of a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide. The polypeptide fragment is often 50 or fewer, 100 or fewer, or 200 or fewer amino acids in length, and is sometimes 300, 400, 500, 600, 700, or 900 or fewer amino acids in length. Ln certain embodiments, the polypeptide fragment comprises, consists essentially of, or consists of, at least 6 consecutive amino acids and not more than 1211 consecutive amino acids of SEQ ED NO: 13-18, or the polypeptide fragment comprises, consists essentially of, or consists of, at least 6 consecutive amino acids and not more than 543 consecutive amino acids of SEQ ED NO: 13-18. [0075] SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptides described herein can be used as immunogens to produce aiάi-SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 antibodies in a subject, to purify SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 ligands or binding partners, and in screening assays to identify molecules which inhibit or enhance the interaction of SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 with a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 substrate. Full-length SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptides and polynucleotides encoding the same may be specifically substituted for a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide fragment or polynucleotide encoding the same in any embodiment described herein. [0076] Substantially identical polypeptides may depart from the amino acid sequences set forth in SEQ ED NO: 13-18 in different manners. For example, conservative amino acid modifications may be introduced at one or more positions in the amino acid sequences of SEQ ED NO: 13-18. A

"conservative amino acid substitution" is one in which the amino acid is replaced by another amino acid having a similar stracture and/or chemical function. Families of amino acid residues having similar stractures and functions are well known. These families include amino acids with basic side chains (e.g, lysine, arginine, histidine), acidic side chains (e.g, aspartic acid, glutamic acid), uncharged polar side chains (e.g, glycine, asparagine, glutamine, serine, threonine, tyrosine, cysteine), nonpolar side chains (e.g, alanine, valine, leucine, isoleucine, proline, phenylalanine, methionine, tryptophan), beta-branched side chains (e.g, threonine, valine, isoleucine) and aromatic side chains (e.g, tyrosine, phenylalanine, tryptophan, histidine). Also, essential and non-essential amino acids may be replaced. A "non-essential" amino acid is one that can be altered without abolishing or substantially altering the biological function of a SPUVE, GRIN3A, PFTKl,

SERPINA5, LOCI 15209 or HRMT1L3 polypeptide, whereas altering an "essential" amino acid abolishes or substantially alters the biological function of a SPUVE, GRIN3A, PFTKl, SERPINA5,

LOCI 15209 or HRMT1L3 polypeptide. Amino acids that are conserved among SPUVE, GRIN3A,

PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptides are typically essential amino acids. [0077] Also, SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptides and polypeptide variants may exist as chimeric or fusion polypeptides. As used herein, a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 "chimeric polypeptide" or "fusion polypeptide" includes a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide linked to a non-SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide. A "non-SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide" refers to a polypeptide having an amino acid sequence corresponding to a polypeptide which is not substantially identical to the SPUVE, GRLN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide, which includes, for example, a polypeptide that is different from the SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide and derived from the same or a different organism. The SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide in the fusion polypeptide can correspond to an entire or nearly entire SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide or a fragment thereof. The non-SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide can be fused to the N-terminus or C-terminus ofthe SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide. [0078] Fusion polypeptides can include a moiety having high affinity for a ligand. For example, the fusion polypeptide can be a GST-SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 fusion polypeptide in which the SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 sequences are fused to the C-terminus ofthe GST sequences, or a polyhistidine- SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 fusion polypeptide in which the SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide is fused at the N- or C-terminus to a string of histidine residues. Such fusion polypeptides can facilitate purification of recombinant SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3. Expression vectors are commercially available that already encode a fusion moiety (e.g, a GST polypeptide), and a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 nucleic acid can be cloned into an expression vector such that the fusion moiety is linked in-frame to the SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide. Further, the fusion polypeptide can be a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide containing a heterologous signal sequence at its N-terminus. In certain host cells (e.g, mammalian host cells), expression, secretion, cellular intemalization, and cellular localization of a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide can be increased through use of a heterologous signal sequence. Fusion polypeptides can also include all or a part of a serum polypeptide (e.g, an IgG constant region or human serum albumin). [0079] SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptides or fragments thereof can be incoφorated into pharmaceutical compositions and administered to a subject in vivo. Administration of these SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptides can be used to affect the bioavailability of a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 substrate and may effectively increase or decrease SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 biological activity in a cell or effectively supplement dysfunctional or hyperactive SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide. SPUVE, GRIN3A, PFTKl, SERPMA5, LOCI 15209 or HRMT1L3 fusion polypeptides may be useful therapeutically for the treatment of disorders caused by, for example, (i) aberrant modification or mutation of a gene encoding a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide; (ii) mis-regulation ofthe SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 gene; and (iii) aberrant post-translational modification of a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide. Also, SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptides can be used as immunogens to produce anti-SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 antibodies in a subject, to purify SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 ligands or binding partners, and in screening assays to identify molecules which inhibit or enhance the interaction of SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 with a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 substrate. Preferably, said SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptides are used in screening assays to identify molecules which inhibit the interaction of SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3. [0080] In addition, polypeptides can be chemically synthesized using techniques known in the art (See, e.g., Creighton, 1983 Proteins. New York, N.Y.: W. H. Freeman and Company; and Hunkapiller et αl, (1984) Nature July 12 -18;310(5973):105-11). For example, a relative short polypeptide fragment can be synthesized by use of a peptide synthesizer. Furthermore, if desired, non-classical amino acids or chemical amino acid analogs can be introduced as a substitution or addition into the fragment sequence. Non-classical amino acids include, but are not limited to, to the D-isomers ofthe common amino acids, 2,4-diaminobutyric acid, a-amino isobutyric acid, 4- aminobutyric acid, Abu, 2-amino butyric acid, g-Abu, e-Ahx, 6-amino hexanoic acid, Aib, 2-amino isobutyric acid, 3-amino propionic acid, oπiithine, norleucine, norvaline, hydroxyproline, sarcosine, citrulline, homocitrulline, cysteic acid, t-butylglycine, t-butylalanine, phenylglycine, cyclohexylalanine, b-alanine, fluoroa ino acids, designer amino acids such as b-methyl amino acids, Ca-methyl amino acids, Na-methyl amino acids, and amino acid analogs in general. Furthermore, the amino acid can be D (dextrorotary) or L (levorotary). [0081] Also included are polypeptide fragments which are differentially modified during or after translation, e.g., by glycosylation, acetylation, phosphorylation, amidation, derivatization by known protectmg blocking groups, proteolytic cleavage, linkage to an antibody molecule or other cellular ligand, and the like. Any of numerous chemical modifications may be carried out by known techniques, including but not limited, to specific chemical cleavage by cyanogen bromide, trypsin, chymotrypsin, papain, V8 protease, NaBH_t; acetylation, formylation, oxidation, reduction; metabolic synthesis in the presence of tunicamycin; and the like. [0082] Additional post-translational modifications include, for example, N-linked or O-linked carbohydrate chains, processing of N-terminal or C-terminal ends), attachment of chemical moieties to the amino acid backbone, chemical modifications of N-linked or O-linked carbohydrate chains, and addition or deletion of an N-terminal methionine residue as a result of prokaryotic host cell expression. The polypeptide fragments may also be modified with a detectable label, such as an enzymatic, fluorescent, isotopic or affinity label to allow for detection and isolation ofthe polypeptide. [0083] Also provided are chemically modified polypeptide derivatives that may provide additional advantages such as increased solubility, stability and circulating time ofthe polypeptide, or decreased immunogenicity. See U.S. Pat. No: 4,179,337. The chemical moieties for derivitization may be selected from water soluble polymers such as polyethylene glycol, ethylene glycol/propylene glycol copolymers, carboxymethylcellulose, dextran, polyvinyl alcohol and the like. The polypeptides may be modified at random positions within the molecule, or at predetermined positions within the molecule and may include one, two, three or more attached chemical moieties. [0084] The polymer may be of any molecular weight, and may be branched or unbranched. For polyethylene glycol, the molecular weight is between about 1 kDa and about 100 kDa (the term "about" indicating that in preparations of polyethylene glycol, some molecules will weigh more, some less, than the stated molecular weight) for ease in handling and manufacturing. Other sizes may be used, depending on the desired therapeutic profile (e.g., the duration of sustained release desired, the effects, if any on biological activity, the ease in handling, the degree or lack of antigenicity and other known effects ofthe polyethylene glycol to a therapeutic protein or analog). [0085] The polyethylene glycol molecules (or other chemical moieties) should be attached to the polypeptide with consideration of effects on functional or antigenic domains ofthe polypeptide. There are a number of attachment methods available to those skilled in the art, e.g, EP 0401 384, herein incoφorated by reference (coupling PEG to G-CSF), see also Malik et al. (1992) Exp Hematol. September;20(8): 1028-35, reporting pegylation of GM-CSF using tresyl chloride). For example, polyethylene glycol may be covalently bound through amino acid residues via a reactive group, such as, a free amino or carboxyl group. Reactive groups are those to which an activated polyethylene glycol molecule may be bound. The amino acid residues having a free amino group may include lysine residues and the N-terminal amino acid residues; those having a free carboxyl group may include aspartic acid residues, glutamic acid residues and the C-terminal amino acid residue. Sulfhydryl groups may also be used as a reactive group for attaching the polyethylene glycol molecules. A polymer sometimes is attached at an amino group, such as attachment at the N-terminus or lysine group. [0086] One may specifically desire proteins chemically modified at the N-terminus. Using polyethylene glycol as an illustration ofthe present composition, one may select from a variety of polyethylene glycol molecules (by molecular weight, branching, and the like), the proportion of polyethylene glycol molecules to protein (polypeptide) molecules in the reaction mix, the type of pegylation reaction to be performed, and the method of obtaining the selected N-terminally pegylated protein. The method of obtaining the N-terminally pegylated preparation (i.e., separating this moiety from other monopegylated moieties if necessary) may be by purification ofthe N- terminally pegylated material from a population of pegylated protein molecules. Selective proteins chemically modified at the N-terminus may be accomplished by reductive alkylation, which exploits differential reactivity of different types of primary amino groups (lysine versus the N- terminal) available for derivatization in a particular protein. Under the appropriate reaction conditions, substantially selective derivatization ofthe protein at the N-terminus with a carbonyl group containing polymer is achieved.

Substantially Identical Nucleic Acids and Polypeptides [0087] Nucleotide sequences and polypeptide sequences that are substantially identical to a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 nucleotide sequence and the SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide sequences encoded by those nucleotide sequences are included herein. The term "substantially identical" as used herein refers to two or more nucleic acids or polypeptides sharing one or more identical nucleotide sequences or polypeptide sequences, respectively. Included are nucleotide sequences or polypeptide sequences that are 55% or more, 60% or more, 65% or more, 70% or more, 75% or more, 80% or more, 85% or more, 90% or more, 95% or more (each often within a 1%, 2%, 3% or 4% variability) or more identical to the nucleotide sequences in SEQ ED NO: 1-12 or the encoded SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide amino acid sequences. One test for determining whether two nucleic acids are substantially identical is to determine the percent of identical nucleotide sequences or polypeptide sequences shared between the nucleic acids or polypeptides. [0088] Calculations of sequence identity are often performed as follows. Sequences are aligned for optimal comparison puφoses (e.g. , gaps can be introduced in one or both of a first and a second amino acid or nucleic acid sequence for optimal alignment and non-homologous sequences can be disregarded for comparison puφoses). The length of a reference sequence aligned for comparison puφoses is sometimes 30% or more, 40% or more, 50% or more, often 60% or more, and more often 70% or more, 80% or more, 90% or more, 90% or more, or 100% ofthe length of the reference sequence. The nucleotides or amino acids at corresponding nucleotide or polypeptide positions, respectively, are then compared among the two sequences. When a position in the first sequence is occupied by the same nucleotide or amino acid as the corresponding position in the second sequence, the nucleotides or amino acids are deemed to be identical at that position. The percent identity between the two sequences is a function ofthe number of identical positions shared by the sequences, taking into account the number of gaps, and the length of each gap, introduced for optimal alignment ofthe two sequences. [0089] Comparison of sequences and determination of percent identity between two sequences can be accomplished using a mathematical algorithm. Percent identity between two amino acid or nucleotide sequences can be determined using the algorithm of Meyers & Miller, CABIOS 4: 11-17 (1989), which has been incoφorated into the ALIGN program (version 2.0), using a PAM120 weight residue table, a gap length penalty of 12 and a gap penalty of 4. Also, percent identity between two amino acid sequences can be determined using the Needleman & Wunsch, J. Mol. Biol. 48: 444-453 (1970) algorithm which has been incoφorated into the GAP program in the GCG software package (available at the http address www.gcg.com), using either a Blossum 62 matrix or a PAM250 matrix, and a gap weight of 16, 14, 12, 10, 8, 6, or 4 and a length weight of 1, 2, 3, 4, 5, or 6. Percent identity between two nucleotide sequences can be determined using the GAP program in the GCG software package (available at http address www.gcg.com), using a NWSgapdna.CMP matrix and a gap weight of 40, 50, 60, 70, or 80 and a length weight of 1, 2, 3, 4, 5, or 6. A set of parameters often used is a Blossum 62 scoring matrix with a gap open penalty of 12, a gap extend penalty of 4, and a frameshift gap penalty of 5. [0090] Another manner for determining if two nucleic acids are substantially identical is to assess whether a polynucleotide homologous to one nucleic acid will hybridize to the other nucleic acid under stringent conditions. As use herein, the term "stringent conditions" .refers to conditions for hybridization and washing. Stringent conditions are known to those skilled in the art and can be found in Current Protocols in Molecular Biology, John Wiley & Sons, N.Y. , 6.3.1-6.3.6 (1989). Aqueous and non-aqueous methods are described in that reference and either can be used. An example of stringent hybridization conditions is hybridization in 6X sodium chloride/sodium citrate (SSC) at about 45°C, followed by one or more washes in 0.2X SSC, 0.1% SDS at 50°C. Another example of stringent hybridization conditions are hybridization in 6X sodium chloride/sodium citrate (SSC) at about 45°C, followed by one or more washes in 0.2X SSC, 0.1% SDS at 55°C. A further example of stringent hybridization conditions is hybridization in 6X sodium chloride/sodium citrate (SSC) at about 45°C, followed by one or more washes in 0.2X SSC, 0.1% SDS at 60°C. Often, stringent hybridization conditions are hybridization in 6X sodium chloride/sodium citrate (SSC) at about 45°C, followed by one or more washes in 0.2X SSC, 0.1% SDS at 65°C. More often, stringency conditions are 0.5M sodium phosphate, 7% SDS at 65°C, followed by one or more washes at 0.2X SSC, 1% SDS at 65°C. [0091] An example of a substantially identical nucleotide sequence to a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 nucleotide sequence is one that has a different nucleotide sequence but still encodes the same polypeptide sequence encoded by the SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 nucleotide sequence. Another example is a nucleotide sequence that encodes a polypeptide having a polypeptide sequence that is more than 70% or more identical to, sometimes 75% or more, 80% or more, or 85% or more identical to, and often 90% or more and 95% or more identical to a polypeptide sequence encoded by a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 nucleotide sequence. [0092] SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 nucleotide sequences and SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 amino acid sequences can be used as "query sequences" to perform a search against public databases to identify other family members or related sequences, for example. Such searches can be performed using the NBLAST and XBLAST programs (version 2.0) of Altschul et al, J. Mol. Biol. 215: 403-10 (1990). BLAST nucleotide searches can be performed with the NBLAST program, score = 100, wordlength = 12 to obtain nucleotide sequences homologous to nucleotide sequences from SEQ ED NO: 1-12. BLAST polypeptide searches can be performed with the XBLAST program, score = 50, wordlength = 3 to obtain amino acid sequences homologous to polypeptides encoded by a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 nucleotide sequence. To obtain gapped alignments for comparison puφoses, Gapped BLAST can be utilized as described in Altschul et al, Nucleic Acids Res. 25(17): 3389-3402 (1997). When utilizing BLAST and Gapped BLAST programs, default parameters ofthe respective programs (e.g., XBLAST and NBLAST) can be used (see the http address www.ncbi.nlm.nih.gov). [0093] A nucleic acid that is substantially identical to a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 nucleotide sequence may include polymoφhic sites at positions equivalent to those described herein when the sequences are aligned. For example, using the alignment procedures described herein, SNPs in a sequence substantially identical to a sequence in SEQ ED NO: 1-12 can be identified at nucleotide positions that match (i.e., align) with nucleotides at SNP positions in the nucleotide sequence of SEQ ED NO: 1-12. Also, where a polymoφhic variation results in an insertion or deletion, insertion or deletion of a nucleotide sequence from a reference sequence can change the relative positions of other polymoφhic sites in the nucleotide sequence. [0094] Substantially identical nucleotide and polypeptide sequences include those that are naturally occurring, such as allelic variants (same locus), splice variants, homologs (different locus), and orthologs (different organism) or can be non-naturally occurring. Non-naturally occurring variants can be generated by mutagenesis techniques, including those applied to polynucleotides, cells, or organisms. The variants can contain nucleotide substitutions, deletions, inversions and insertions. Variation can occur in either or both the coding and non-coding regions. The variations can produce both conservative and non-conservative amino acid substitutions (as compared in the encoded product). Orthologs, homologs, allelic variants, and splice variants can be identified using methods known in the art. These variants normally comprise a nucleotide sequence encoding a polypeptide that is 50% or more, about 55% or more, often about 70-75% or more, more often about 80-85% or more, and typically about 90-95% or more identical to the amino acid sequences of target polypeptides or a fragment thereof. Such nucleic acid molecules readily can be identified as being able to hybridize under stringent conditions to a nucleotide sequence in SEQ ED NO: 1-12 or a fragment thereof. Nucleic acid molecules corresponding to orthologs, homologs, and allelic variants of a nucleotide sequence in SEQ ED NO: 1-12 can be identified by mapping the sequence to the same chromosome or locus as the nucleotide sequence in SEQ ED NO: 1-12. [0095] Also, substantially identical nucleotide sequences may include codons that are altered with respect t© the naturally occurring sequence for enhancing expression of a target polypeptide in a particular expression system. For example, the nucleic acid can be one in which one or more codons are altered, and often 10% or more or 20% or more ofthe codons are altered for optimized expression in bacteria (e.g., E. coli.), yeast (e.g., S. cervesiae), human (e.g., 293 cells), insect, or rodent (e.g., hamster) cells.

Methods for Identifying Subjects at Risk of Breast Cancer and Breast Cancer Risk in a Subject [0096] Methods for prognosing and diagnosing breast cancer in subjects are provided herein. These methods include detecting the presence or absence of one or more polymoφhic variations associated with breast cancer in a nucleotide sequence set forth in SEQ ED NO: 1-6, or substantially identical sequence thereof, in a sample from a subject, where the presence of a polymoφhic variant is indicative of a risk of breast cancer. [0097] Thus, featured herein is a method for detecting a subject at risk of breast cancer or the risk of breast cancer in a subject, which comprises detecting the presence or absence of a polymorphic variation associated with breast cancer at a polymorphic site in a nucleic acid sample from a subject, where the nucleotide sequence comprises a polynucleotide sequence selected from the group consisting of: (a) a nucleotide sequence set forth in SEQ ED NO: 1-6; (b) a nucleotide sequence which encodes a polypeptide having an amino acid sequence encoded by a nucleotide sequence in SEQ ED NO: 1-6; (c) a nucleotide sequence which encodes a polypeptide that is 90% or more identical to an amino acid sequence encoded by a nucleotide sequence in SEQ ED NO: 1-6 or a nucleotide sequence about 90% or more identical to the nucleotide sequence set forth in SEQ ED NO: 1-6; and (d) a fragment of a nucleotide sequence of (a), (b), or (c), often a fragment that includes a polymoφhic site associated with breast cancer; whereby the presence ofthe polymoφhic variation is indicative of a risk of breast cancer in the subject. In certain embodiments, determining the presence of a combination of two or more polymoφhic variants associated with breast cancer in one or more nucleotide sequences ofthe sample is determined to identify a subject at risk of breast cancer and/or risk of breast cancer. [0098] A risk of developing aggressive forms of breast cancer likely to metastasize or invade surrounding tissues (e.g. Stage EQA, HEB, and EV breast cancers), and subjects at risk of developing aggressive forms of breast cancer also may be identified by the methods described herein. These methods include collecting phenotype information from subjects having breast cancer, which includes the stage of progression ofthe breast cancer, and performing a secondary phenotype analysis to detect the presence or absence of one or more polymoφhic variations associated with a particular stage form of breast cancer. Thus, detecting the presence or absence of one or more polymoφhic variations in a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 nucleotide sequence associated with a late stage form of breast cancer often is prognostic and/or diagnostic of an aggressive form ofthe cancer. [0099] Results from prognostic tests may be combined with other test results to diagnose breast cancer. For example, prognostic results may be gathered, a patient sample may be ordered based on a determined predisposition to breast cancer, the patient sample is analyzed, and the results ofthe analysis may be utilized to diagnose breast cancer. Also breast cancer diagnostic methods can be developed from studies used to generate prognostic/diagnostic methods in which populations are stratified into subpopulations having different progressions of breast cancer. In another embodiment, prognostic results may be gathered; a patient's risk factors for developing breast cancer analyzed (e.g., age, race, family history, age of first menstrual cycle, age at birth of first child); and a patient sample may be ordered based on a determined predisposition to breast cancer. In an alternative embodiment, the results from predisposition analyses described herein may be combined with other test results indicative of breast cancer, which were previously, concurrently, or subsequently gathered with respect to the predisposition testing. In these embodiments, the combination ofthe prognostic test results with other test results can be probative of breast cancer, and the combination can be utilized as a breast cancer diagnostic. The results of any test indicative of breast cancer known in the art may be combined with the methods described herein. Examples of such tests are mammography (e.g., a more frequent and/or earlier mammography regimen may be prescribed); breast biopsy and optionally a biopsy from another tissue; breast ultrasound and optionally an ultrasound analysis of another tissue; breast magnetic resonance imaging (MRE) and optionally an MRI analysis of another tissue; electrical impedance (T-scan) analysis of breast and optionally of another tissue; ductal lavage; nuclear medicine analysis (e.g., scintimammography); BRCA1 and/or BRCA2 sequence analysis results; and thermal imaging ofthe breast and optionally of another tissue. Testing may be performed on tissue other than breast to diagnose the occurrence of metastasis (e.g., testing ofthe lymph node). [0100] Risk of breast cancer sometimes is expressed as a probability, such as an odds ratio, percentage, or risk factor. The risk is based upon the presence or absence of one or more polymoφhic variants described herein, and also may be based in part upon phenotypic traits ofthe individual being tested. Methods for calculating predispositions based upon patient data are well known (see, e.g., Agresti, Categorical Data Analysis, 2nd Ed. 2002. Wiley). Allelotyping and genotyping analyses may be carried out in populations other than those exemplified herein to enhance the predictive power ofthe prognostic method. These further analyses are executed in view ofthe exemplified procedures described herein, and may be based upon the same polymoφhic variations or additional polymoφhic variations. Risk determinations for breast cancer are useful in a variety of applications. In one embodiment, breast cancer risk determinations are used by clinicians to direct appropriate detection, preventative and treatment procedures to subjects who most require these. In another embodiment, breast cancer risk determinations are used by health insurers for preparing actuarial tables and for calculating insurance premiums. [0101] The nucleic acid sample typically is isolated from a biological sample obtained from a subject. For example, nucleic acid can be isolated from blood, saliva, sputum, urine, cell scrapings, and biopsy tissue. The nucleic acid sample can be isolated from a biological sample using standard techniques, such as the technique described in Example 2. As used herein, the term "subject" refers primarily to humans but also refers to other mammals such as dogs, cats, and ungulates (e.g., cattle, sheep, and swine). Subjects also include avians (e.g., chickens and turkeys), reptiles, and fish (e.g., salmon), as embodiments described herein can be adapted to nucleic acid samples isolated from any of these organisms. The nucleic acid sample may be isolated from the subject and then directly utilized in a method for determining the presence of a polymoφhic variant, or alternatively, the sample may be isolated and then stored (e.g., frozen) for a period of time before being subjected to analysis. [0102] The presence or absence of a polymoφhic variant is determined using one or both chromosomal complements represented in the nucleic acid sample. Determining the presence or absence of a polymoφhic variant in both chromosomal complements represented in a nucleic acid sample from a subject having a copy of each chromosome is useful for determining the zygosity of an individual for the polymoφhic variant (i.e., whether the individual is homozygous or heterozygous for the polymoφhic variant). Any oligonucleotide-based diagnostic may be utilized to determine whether a sample includes the presence or absence of a polymoφhic variant in a sample. For example, primer extension methods, ligase sequence determination methods (e.g., U.S. Pat. Nos. 5,679,524 and 5,952,174, and WO 01/27326), mismatch sequence determination methods (e.g., U.S. Pat. Nos. 5,851,770; 5,958,692; 6,110,684; and 6,183,958), microarray sequence determination methods, restriction fragment length polymoφhism (RFLP), single strand conformation polymoφhism detection (SSCP) (e.g., U.S. Pat. Nos. 5,891,625 and 6,013,499), PCR- based assays (e.g., TAQMAN^® PCR System (Applied Biosystems)), and nucleotide sequencing methods may be used. [0103] Oligonucleotide extension methods typically involve providing a pair of oligonucleotide primers in a polymerase chain reaction (PCR) or in other nucleic acid amplification methods for the puφose of amplifying a region from the nucleic acid sample that comprises the polymoφhic variation. One oligonucleotide primer is complementary to a region 3' ofthe polymoφhism and the other is complementary to a region 5' ofthe polymoφhism. A PCR primer pair may be used in methods disclosed in U.S. Pat. Nos. 4,683,195; 4,683,202, 4,965,188; 5,656,493; 5,998,143; 6,140,054; WO 01/27327; and WO 01/27329 for example. PCR primer pairs may also be used in any commercially available machines that perform PCR, such as any ofthe GENEAMP^® Systems available from Applied Biosystems. Also, those of ordinary skill in the art will be able to design oligonucleotide primers based upon a nucleotide sequence set forth in SEQ ID NO: 1-6 without undue experimentation using knowledge readily available in the art. [0104] Also provided is an extension oligonucleotide that hybridizes to the amplified fragment adjacent to the polymoφhic variation. As used herein, the term "adjacent" refers to the 3' end of the extension oligonucleotide being often 1 nucleotide from the 5' end ofthe polymoφhic site, and sometimes 2, 3, 4, 5, 6, 7, 8, 9, or 10 nucleotides from the 5' end ofthe polymoφhic site, in the nucleic acid when the extension oligonucleotide is hybridized to the nucleic acid. The extension oligonucleotide then is extended by one or more nucleotides, and the number and/or type of nucleotides that are added to the extension oligonucleotide determine whether the polymoφhic variant is present. Oligonucleotide extension methods are disclosed, for example, in U.S. Pat. Nos. 4,656,127; 4,851,331; 5,679,524; 5,834,189; 5,876,934; 5,908,755; 5,912,118; 5,976,802; 5,981,186; 6,004,744; 6,013,431; 6,017,702; 6,046,005; 6,087,095; 6,210,891; and WO 01/20039. Oligonucleotide extension methods using mass spectrometry are described, for example, in U.S. Pat. Nos. 5,547,835; 5,605,798; 5,691,141; 5,849,542; 5,869,242; 5,928,906; 6,043,031; and 6,194,144, and a method often utilized is described herein in Example 2. Multiple extension oligonucleotides may be utilized in one reaction, which is referred to herein as "multiplexing." [0105] A microarray can be utilized for deteririining whether a polymoφhic variant is present or absent in a nucleic acid sample. A microarray may include any oligonucleotides described herein, and methods for making and using oligonucleotide microarrays suitable for diagnostic use are disclosed in U.S. Pat. Nos. 5,492,806; 5,525,464; 5,589,330; 5,695,940; 5,849,483; 6,018,041; 6,045,996; 6,136,541; 6,142,681; 6,156,501; 6,197,506; 6,223,127; 6,225,625; 6,229,911; 6,239,273; WO 00/52625; WO 01/25485; and WO 01/29259. The microarray typically comprises a solid support and the oligonucleotides may be linked to this solid support by covalent bonds or by non-covalent interactions. The oligonucleotides may also be linked to the solid support directly or by a spacer molecule. A microarray may comprise one or more oligonucleotides complementary to a polymoφhic site set forth in SEQ ED NO: 1-6 or below. [0106] A kit also may be utilized for determining whether a polymoφhic variant is present or absent in a nucleic acid sample. A kit often comprises one or more pairs of oligonucleotide primers useful for amplifying a fragment of a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 nucleotide sequence or a substantially identical sequence thereof, where the fragment includes a polymoφhic site. The kit sometimes comprises a polymerizing agent, for example, a thermostable nucleic acid polymerase such as one disclosed in U.S. Pat. Nos. 4,889,818 or 6,077,664. Also, the kit often comprises an elongation oligonucleotide that hybridizes to a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 nucleotide sequence in a nucleic acid sample adjacent to the polymoφhic site. Where the kit includes an elongation oligonucleotide, it also often comprises chain elongating nucleotides, such as dATP, dTTP, dGTP, dCTP, and dITP, including analogs of dATP, dTTP, dGTP, dCTP and dITP, provided that such analogs are substrates for a thermostable nucleic acid polymerase and can be incoφorated into a nucleic acid chain elongated from the extension oligonucleotide. Along with chain elongating nucleotides would be one or more chain terminating nucleotides such as ddATP, ddTTP, ddGTP, ddCTP, and the like. In an embodiment, the kit comprises one or more oligonucleotide primer pairs, a polymerizing agent, chain elongating nucleotides, at least one elongation oligonucleotide, and one or more chain terminating nucleotides. Kits optionally include buffers, vials, microtiter plates, and instractions for use. [0107] An individual identified as being at risk of breast cancer may be heterozygous or homozygous with respect to the allele associated with a higher risk of breast cancer. A subject homozygous for an allele associated with an increased risk of breast cancer is at a comparatively high risk of breast cancer, a subject heterozygous for an allele associated with an increased risk of breast cancer is at a comparatively intermediate risk of breast cancer, and a subject homozygous for an allele associated with a decreased risk of breast cancer is at a comparatively low risk of breast cancer. A genotype may be assessed for a complementary strand, such that the complementary nucleotide at a particular position is detected. [0108] Also featured are methods for determining risk of breast cancer and/or identifying a subject at risk of breast cancer by contacting a polypeptide or protein encoded by a SPUVE,

GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 nucleotide sequence from a subject with an antibody that specifically binds to an epitope associated with increased risk of breast cancer in the polypeptide. En certain embodiments, the antibody specifically binds to an epitope that comprises a leucine at amino acid position 359 in SEQ ED NO: 16, a leucine at amino acid position 378 in SEQ ED NO: 16, or an alanine at amino acid position 857 in SEQ ED NO: 16, a proline at amino acid position 352 in SEQ ED NO: 14 or an alanine at amino acid position 348 in SEQ ED NO: 14.

Applications of Prognostic and Diagnostic Results to Pharmacogenomic Methods [0109] Pharmacogenomics is a discipline that involves tailoring a treatment for a subject according to the subject's genotype. For example, based upon the outcome of a prognostic test described herein, a clinician or physician may target pertinent information and preventative or therapeutic treatments to a subject who would be benefited by the information or treatment and avoid directing such information and treatments to a subject who would not be benefited (e.g., the treatment has no therapeutic effect and/or the subject experiences adverse side effects). As therapeutic approaches for breast cancer continue to evolve and improve, the goal of treatments for breast cancer related disorders is to intervene even before clinical signs (e.g., identification of lump in the breast) first manifest. Thus, genetic markers associated with susceptibility to breast cancer prove useful for early diagnosis, prevention and treatment of breast cancer. [0110] The following is an example of a pharmacogenomic embodiment. A particular treatment regimen can exert a differential effect depending upon the subject's genotype. Where a candidate therapeutic exhibits a significant interaction with a major allele and a comparatively weak interaction with a minor allele (e.g., an order of magnitude or greater difference in the interaction), such a therapeutic typically would not be administered to a subject genotyped as being homozygous for the minor allele, and sometimes not administered to a subject genotyped as being heterozygous for the minor allele. En another example, where a candidate therapeutic is not significantly toxic when administered to subjects who are homozygous for a major allele but is comparatively toxic when administered to subjects heterozygous or homozygous for a minor allele, the candidate therapeutic is not typically administered to subjects who are genotyped as being heterozygous or homozygous with respect to the minor allele. [0111] The methods described herein are applicable to pharmacogenomic methods for detecting, preventing, alleviating and/or treating breast cancer. For example, a nucleic acid sample from an individual may be subjected to a genetic test described herein. Where one or more polymoφhic variations associated with increased risk of breast cancer are identified in a subject, information for detecting, preventing or treating breast cancer and/or one or more breast cancer detection, prevention and/or treatment regimens then may be directed to and/or prescribed to that subject. [0112] En certain embodiments, a detection, prevenative and/or treatment regimen is specifically prescribed and/or administered to individuals who will most benefit from it based upon their risk of developing breast cancer assessed by the methods described herein. Thus, provided are methods for identifying a subject at risk of breast cancer and then prescribing a detection, therapeutic or preventative regimen to individuals identified as being at risk of breast cancer. Thus, certain embodiments are directed to methods for treating breast cancer in a subject, reducing risk of breast cancer in a subject, or early detection of breast cancer in a subject, which comprise: detecting the presence or absence of a polymoφhic variant associated with breast cancer in a nucleotide sequence in a nucleic acid sample from a subject, where the nucleotide sequence comprises a polynucleotide sequence selected from the group consisting of: (a) a nucleotide sequence set forth in SEQ ED NO: 1-6; (b) a nucleotide sequence which encodes a polypeptide having an amino acid sequence encoded by a nucleotide sequence in SEQ ED NO: 1-6; (c) a nucleotide sequence which encodes a polypeptide that is 90% or more identical to an amino acid sequence encoded by a nucleotide sequence in SEQ ED NO: 1-6 or a nucleotide sequence about 90% or more identical to the nucleotide sequence set forth in SEQ ED NO: 1-6; and (d) a fragment of a nucleotide sequence of (a), (b), or (c), sometimes comprising a polymoφhic site associated with breast cancer; and prescribing or administering a breast cancer treatment regimen, preventative regimen and/or detection regimen to a subject from whom the sample originated where the presence of one or more polymoφhic variations associated with breast cancer are detected in the nucleotide sequence. En these methods, genetic results may be utilized in combination with other test results to diagnose breast cancer as described above. Other test results include but are not limited to mammography results, imaging results, biopsy results and results from BRCA1 or BRAC2 test results, as described above. [0113] Detection regimens include one or more mammography procedures, a regular mammography regimen (e.g., once a year, or once every six, four, three or two months); an early mammography regimen (e.g., mammography tests are performed beginning at age 25, 30, or 35); one or more biopsy procedures (e.g., a regular biopsy regimen beginning at age 40); breast biopsy and biopsy from other tissue; breast ultrasound and optionally ultrasound analysis of another tissue; breast magnetic resonance imaging (MRI) and optionally MRI analysis of another tissue; electrical impedance (T-scan) analysis of breast and optionally another tissue; ductal lavage; nuclear medicine analysis (e.g., scintimammography); BRCA1 and or BRCA2 sequence analysis results; and/or thermal imaging ofthe breast and optionally another tissue. [0114] Treatments sometimes are preventative (e.g., is prescribed or administered to reduce the probability that a breast cancer associated condition arises or progresses), sometimes are therapeutic, and sometimes delay, alleviate or halt the progression of breast cancer. Any known preventative or therapeutic treatment for alleviating or preventing the occurrence of breast cancer is prescribed and/or administered. For example, certain preventative treatments often are prescribed to subjects having a predisposition to breast cancer and where the subject is not diagnosed with breast cancer or is diagnosed as having symptoms indicative of early stage breast cancer (e.g., stage I). For subjects not diagnosed as having breast cancer, any preventative treatments known in the art can be prescribed and administered, which include selective hormone receptor modulators (e.g., selective estrogen receptor modulators (SERMs) such as tamoxifen, reloxifene, and toremifene); compositions that prevent production of hormones (e.g., aramotase inhibitors that prevent the production of estrogen in the adrenal gland, such as exemestane, letrozole, anastrozol, groserelin, and megestrol); other hormonal treatments (e.g., goserelin acetate and fulvestrant); biologic response modifiers such as antibodies (e.g., trastuzumab (herceptin/HER2)); surgery (e.g., lumpectomy and mastectomy); drugs that delay or halt metastasis (e.g., pamidronate disodium); and alternative/complementary medicine (e.g., acupuncture, acupressure, moxibustion, qi gong, reiki, ayurveda, vitamins, minerals, and herbs (e.g., astragalus root, burdock root, garlic, green tea, and licorice root)). [0115] The use of breast cancer treatments are well known in the art, and include surgery, chemotherapy and/or radiation therapy. Any ofthe treatments may be used in combination to treat or prevent breast cancer (e.g., surgery followed by radiation therapy or chemotherapy). Examples of chemotherapeutics are taxanes (e.g, docetaxel or paclitaxel), and examples of chemotherapy combinations used to treat breast cancer include: cyclophosphamide (Cytoxan), methotrexate (Amethopterin, Mexate, Folex), and fluorouracil (Fluorouracil, 5-Fu, Adrucil), which is referred to as CMF; cyclophosphamide, doxorubicin (Adriamycin), and fluorouracil, which is referred to as CAF; and doxorubicin (Adriamycin) and cyclophosphamide, which is referred to as AC. [0116] As breast cancer preventative and treatment information can be specifically targeted to subjects in need thereof (e.g., those at risk of developing breast cancer or those that have early signs of breast cancer), provided herein is a method for preventing or reducing the risk of developing breast cancer in a subject, which comprises: (a) detecting the presence or absence of a polymoφhic variation associated with breast cancer at a polymoφhic site in a nucleotide sequence in a nucleic acid sample from a subject; (b) identifying a subject with a predisposition to breast cancer, whereby the presence ofthe polymoφhic variation is indicative of a predisposition to breast cancer in the subject; and (c) if such a predisposition is identified, providing the subject with information about methods or products to prevent or reduce breast cancer or to delay the onset of breast cancer. Also provided is a method of targeting information or advertising to a subpopulation of a human population based on the subpopulation being genetically predisposed to a disease or condition, which comprises: (a) detecting the presence or absence of a polymoφhic variation associated with breast cancer at a polymoφhic site in a nucleotide sequence in a nucleic acid sample from a subject;

(b) identifying the subpopulation of subjects in which the polymorphic variation is associated with breast cancer; and (c) providing information only to the subpopulation of subjects about a particular product which may be obtained and consumed or applied by the subject to help prevent or delay onset ofthe disease or condition. [0117] Pharmacogenomics methods also may be used to analyze and predict a response to a breast cancer treatment or a drug. For example, if pharmacogenomics analysis indicates a likelihood that an individual will respond positively to a breast cancer treatment with a particular drug, the drag may be administered to the individual. Conversely, if the analysis indicates that an individual is likely to respond negatively to treatment with a particular drag, an alternative course of treatment may be prescribed. A negative response may be defined as either the absence of an efficacious response or the presence of toxic side effects. The response to a therapeutic treatment can be predicted in a background study in which subjects in any ofthe following populations are genotyped: a population that responds favorably to a treatment regimen, a population that does not respond significantly to a treatment regimen, and a population that responds adversely to a treatment regiment (e.g., exhibits one or more side effects). These populations are provided as examples and other populations and subpopulations may be analyzed. Based upon the results of these analyses, a subject is genotyped to predict whether he or she will respond favorably to a treatment regimen, not respond significantly to a treatment regimen, or respond adversely to a treatment regimen. [0118] The methods described herein also are applicable to clinical drug trials. One or more polymorphic variants indicative of response to an agent for treating breast cancer or to side effects to an agent for treating breast cancer may be identified using the methods described herein. Thereafter, potential participants in clinical trials of such an agent may be screened to identify those individuals most likely to respond favorably to the drag and exclude those likely to experience side effects. En that way, the effectiveness of drag treatment may be measured in individuals who respond positively to the drug, without lowering the measurement as a result ofthe inclusion of individuals who are unlikely to respond positively in the study and without risking undesirable safety problems. En certain embodiments, the agent for treating breast cancer described herein targets SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 or a target in the SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 pathway. [0119] Thus, another embodiment is a method of selecting an individual for inclusion in a clinical trial of a treatment or drag comprising the steps of: (a) obtaining a nucleic acid sample from an individual; (b) determining the identity of a polymorphic variation which is associated with a positive response to the treatment or the drag, or at least one polymoφhic variation which is associated with a negative response to the treatment or the drug in the nucleic acid sample, and (c) including the individual in the clinical trial if the nucleic acid sample contains said polymorphic variation associated with a positive response to the treatment or the drag or if the nucleic acid sample lacks said polymorphic variation associated with a negative response to the treatment or the drag. In addition, the methods for selecting an individual for inclusion in a clinical trial of a treatment or drag encompass methods with any further limitation described in this disclosure, or those following, specified alone or in any combination. The polymorphic variation may be in a sequence selected individually or in any combination from the group consisting of (i) a polynucleotide sequence set forth in SEQ ED NO: 1-6; (ii) a polynucleotide sequence that is 90% or more identical to a nucleotide sequence set forth in SEQ ED NO: 1-6; (iii) a polynucleotide sequence that encodes a polypeptide having an amino acid sequence identical to or 90% or more identical to an amino acid sequence encoded by a nucleotide sequence set forth in SEQ ED NO: 1-6; and (iv) a fragment of a polynucleotide sequence of (i), (ii), or (iii) comprising the polymoφhic site. The including step (c) optionally comprises admi stering the drug or the treatment to the individual if the nucleic acid sample contains the polymoφhic variation associated with a positive response to the treatment or the drag and the nucleic acid sample lacks said biallelic marker associated with a negative response to the treatment or the drag. [0120] Also provided herein is a method of partnering between a diagnostic/prognostic testing provider and a provider of a consumable product, which comprises: (a) the diagnostic/prognostic testing provider detects the presence or absence of a polymorphic variation associated with breast cancer at a polymoφhic site in a nucleotide sequence in a nucleic acid sample from a subject; (b) the diagnostic/prognostic testing provider identifies the subpopulation of subjects in which the polymoφhic variation is associated with breast cancer; (c) the diagnostic/prognostic testing provider forwards information to the subpopulation of subjects about a particular product which may be obtained and consumed or applied by the subject to help prevent or delay onset ofthe disease or condition; and (d) the provider of a consumable product forwards to the diagnostic test provider a fee every time the diagnostic/prognostic test provider forwards information to the subject as set forth in step (c) above.

Compositions Comprising Breast Cancer-Directed Molecules [0121] Featured herein is a composition comprising a breast cancer cell and one or more molecules specifically directed and targeted to a nucleic acid comprising a SPUVE, GRIN3A,

PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 nucleotide sequence or a SPUVE, GRIN3A, PFTKl,

SERPINA5, LOCI 15209 or HRMT1L3 polypeptide. Such directed molecules include, but are not limited to, a compound that binds to a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or

HRMT1L3 nucleic acid or a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide; a RNAi or siRNA molecule having a strand complementary to a SPUVE, GRIN3A,

PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 nucleotide sequence; an antisense nucleic acid complementary to an RNA encoded by a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 DNA sequence; a ribozyme that hybridizes to a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 nucleotide sequence; a nucleic acid aptamer that specifically binds a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide; and an antibody that specifically binds to a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide or binds to a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 nucleic acid. En certain embodiments, the antibody specifically binds to an epitope that comprises a lysine at amino acid position 105 in SEQ ED NO: 16. In specific embodiments, the breast cancer directed molecule interacts with a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 nucleic acid or polypeptide variant associated with breast cancer. In other embodiments, the breast cancer directed molecule interacts with a polypeptide involved in the SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 signal pathway, or a nucleic acid encoding such a polypeptide. Polypeptides involved in the SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 signal pathway are discussed herein. [0122] Compositions sometimes include an adjuvant known to stimulate an immune response, and in certain embodiments, an adjuvant that stimulates a T-cell lymphocyte response. Adjuvants are known, including but not limited to an aluminum adjuvant (e.g., aluminum hydroxide); a cytokine adjuvant or adjuvant that stimulates a cytokine response (e.g., interleukin (EL)-12 and/or ?- interferon cytokines); a Freund-type mineral oil adjuvant emulsion (e.g., Freund's complete or incomplete adjuvant); a synthetic lipoid compound; a copolymer adjuvant (e.g., TitreMax); a saponin; Quil A; a liposome; an oil-in-water emulsion (e.g., an emulsion stabilized by Tween 80 and pluronic polyoxyethlene/polyoxypropylene block copolymer (Syntex Adjuvant Formulation); TitreMax; detoxified endotoxin (MPL) and mycobacterial cell wall components (TDW, CWS) in 2% squalene (Ribi Adjuvant System)); a muramyl dipeptide; an immune-stimulating complex (ISCOM, e.g., an Ag-modified saponin/cholesterol micelle that forms stable cage-like stracture); an aqueous phase adjuvant that does not have a depot effect (e.g., Gerbu adjuvant); a carbohydrate polymer (e.g., AdjuPrime); L-tyrosine; a manide-oleate compound (e.g., Montanide); an ethylene- vinyl acetate copolymer (e.g., Elvax 40W1,2); or lipid A, for example. Such compositions are useful for generating an immune response against a breast cancer directed molecule (e.g., an HLA- binding subsequence within a polypeptide encoded by a nucleotide sequence in SEQ ED NO: 1-6). En such methods, a peptide having an amino acid subsequence of a polypeptide encoded by a nucleotide sequence in SEQ ED NO: 1-6 is delivered to a subject, where the subsequence binds to an HLA molecule and induces a CTL lymphocyte response. The peptide sometimes is delivered to the subject as an isolated peptide or as a minigene in a plasmid that encodes the peptide. Methods for identifying HLA-binding subsequences in such polypeptides are known (see e.g., publication WO02/20616 and PCT application US98/01373 for methods of identifying such sequences). [0123] The breast cancer cell may be in a group of breast cancer cells and/or other types of cells cultured in vitro or in a tissue having breast cancer cells (e.g., a melanocytic lesion) maintained in vitro or present in an animal in vivo (e.g., a rat, mouse, ape or human). En certain embodiments, a composition comprises a component from a breast cancer cell or from a subject having a breast cancer cell instead ofthe breast cancer cell or in addition to the breast cancer cell, where the component sometimes is a nucleic acid molecule (e.g., genomic DNA), a protein mixture or isolated protein, for example. The aforementioned compositions have utility in diagnostic, prognostic and pharmacogenomic methods described previously and in breast cancer therapeutics described hereafter. Certain breast cancer molecules are described in greater detail below.

Compounds [0124] Compounds can be obtained using any ofthe numerous approaches in combinatorial library methods known in the art, including: biological libraries; peptoid libraries (libraries of molecules having the functionalities of peptides, but with a novel, non-peptide backbone which are resistant to enzymatic degradation but which nevertheless remain bioactive (see, e.g., Zuckermann et αl, J. Med. Chem.37: 2678-85 (1994)); spatially addressable parallel solid phase or solution phase libraries; synthetic library methods requiring deconvolution; "one-bead one-compound" library methods; and synthetic library methods using affinity chromatography selection. Biological library and peptoid library approaches are typically limited to peptide libraries, while the other approaches are applicable to peptide, non-peptide oligomer or small molecule libraries of compounds (Lam, Anticancer Drug Des. 12: 145, (1997)). Examples of methods for synthesizing molecular libraries are described, for example, in DeWitt et αl., Proc. Natl. Acad. Sci. U.S.A. 90: 6909 (1993); Erb et αl, Proc. Natl. Acad. Sci. USA 91: 11422 (1994); Zuckermann et αl., J. Med. Chem. 37: 2678 (1994); Cho et αl., Science 261 : 1303 (1993); Carrell et αl., Angew. Chem. Int. Ed. Engl. 33: 2059 (1994); Carell et αl, Angew. Chem. Ent. Ed. Engl. 33: 2061 (1994); and in Gallop et αl., J. Med. Chem. 37: 1233 (1994). [0125] Libraries of compounds may be presented in solution (e.g. , Houghten, Biotechniques 13: 412-421 (1992)), or on beads (Lam, Nature 354: 82-84 (1991)), chips (Fodor, Nature 364: 555- 556 (1993)), bacteria or spores (Ladner, United States Patent No. 5,223,409), plasmids (Cull et αl., Proc. Natl. Acad. Sci. USA 89: 1865-1869 (1992)) or on phage (Scott and Smith, Science 249: 386- 390 (1990); Devlin, Science 249: 404-406 (1990); Cwirla et αl, Proc. Natl. Acad. Sci. 87: 6378- 6382 (1990); Felici, J. Mol. Biol. 222: 301-310 (1991); Ladner supra.). [0126] A compound sometimes alters expression and sometimes alters activity of a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide and may be a small molecule. Small molecules include, but are not limited to, peptides, peptidomimetics (e.g., peptoids), amino acids, amino acid analogs, polynucleotides, polynucleotide analogs, nucleotides, nucleotide analogs, organic or inorganic compounds (i.e, including heteroorganic and organometallic compounds) having a molecular weight less than about 10,000 grams per mole, organic or inorganic compounds having a molecular weight less than about 5,000 grams per mole, organic or inorganic compounds having a molecular weight less than about 1,000 grams per mole, organic or inorganic compounds having a molecular weight less than about 500 grams per mole, and salts, esters, and other pharmaceutically acceptable forms of such compounds.

Antisense Nucleic Acid Molecules. Ribozymes, RNAi, siRNA and Modified Nucleic Acid Molecules [0127] An "antisense" nucleic acid refers to a nucleotide sequence complementary to a "sense" nucleic acid encoding a polypeptide, e.g., complementary to the coding strand of a double-stranded cDNA molecule or complementary to an mRNA sequence. The antisense nucleic acid can be complementary to an entire coding strand in SEQ ID NO: 1-12, or to a portion thereof or a substantially identical sequence thereof. In another embodiment, the antisense nucleic acid molecule is antisense to a "noncoding region" ofthe coding strand of a nucleotide sequence in SEQ ID NO: 1-12 (e.g., 5' and 3' untranslated regions). [0128] An antisense nucleic acid can be designed such that it is complementary to the entire coding region of an mRNA encoded by a nucleotide sequence in SEQ ED NO: 1-6 (e.g, SEQ ID NO: 7-12), and often the antisense nucleic acid is an oligonucleotide antisense to only a portion of a coding or noncoding region ofthe mRNA. For example, the antisense oligonucleotide can be complementary to the region surrounding the translation start site ofthe mRNA, e.g., between the - 10 and +10 regions ofthe target gene nucleotide sequence of interest. An antisense oligonucleotide can be, for example, about 7, 10, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 65, 70, 75, 80, or more nucleotides in length. The antisense nucleic acids, which include the ribozymes described hereafter, can be designed to target a nucleotide sequence in SEQ ID NO: 1-12, often a variant associated with breast cancer, or a substantially identical sequence thereof. Among the variants, minor alleles and major alleles can be targeted, and those associated with a higher risk of breast cancer are often designed, tested, and administered to subjects. [0129] An antisense nucleic acid can be constructed using chemical synthesis and enzymatic ligation reactions using standard procedures. For example, an antisense nucleic acid (e.g., an antisense oligonucleotide) can be chemically synthesized using naturally occurring nucleotides or variously modified nucleotides designed to increase the biological stability ofthe molecules or to increase the physical stability ofthe duplex formed between the antisense and sense nucleic acids, e.g., phosphorothioate derivatives and acridine substituted nucleotides can be used. Antisense nucleic acid also can be produced biologically using an expression vector into which a nucleic acid has been subcloned in an antisense orientation (i.e., RNA transcribed from the inserted nucleic acid will be of an antisense orientation to a target nucleic acid of interest, described further in the following subsection). [0130] When utilized as therapeutics, antisense nucleic acids typically are administered to a subject (e.g., by direct injection at a tissue site) or generated in situ such that they hybridize with or bind to cellular mRNA and/or genomic DNA encoding a polypeptide and thereby inhibit expression ofthe polypeptide, for example, by inhibiting transcription and/or translation. Alternatively, antisense nucleic acid molecules can be modified to target selected cells and then are administered systemically. For systemic administration, antisense molecules can be modified such that they specifically bind to receptors or antigens expressed on a selected cell surface, for example, by linking antisense nucleic acid molecules to peptides or antibodies which bind to cell surface receptors or antigens. Antisense nucleic acid molecules can also be delivered to cells using the vectors described herein. Sufficient intracellular concentrations of antisense molecules are achieved by incoφorating a strong promoter, such as a pol EC or pol UI promoter, in the vector construct. [0131] Antisense nucleic acid molecules sometimes are alpha-anomeric nucleic acid molecules. An alpha-anomeric nucleic acid molecule forms specific double-stranded hybrids with complementary RNA in which, contrary to the usual beta-units, the strands run parallel to each other (Gaultier et al, Nucleic Acids. Res. 15: 6625-6641 (1987)). Antisense nucleic acid molecules can also comprise a 2'-o-methylribonucleotide (fnoue et al, Nucleic Acids Res. 15: 6131-6148 (1987)) or a chimeric RNA-DNA analogue (Inoue et al, FEBS Lett. 215: 327-330 (1987)). Antisense nucleic acids sometimes are composed of DNA or PNA or any other nucleic acid derivatives described previously. [0132] Ln another embodiment, an antisense nucleic acid is a ribozyme. A ribozyme having specificity for a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 nucleotide sequence can include one or more sequences complementary to such a nucleotide sequence, and a sequence having a known catalytic region responsible for mRNA cleavage (see e.g., U.S. Pat. No. 5,093,246 or Haselhoff and Gerlach, Nature 334: 585-591 (1988)). For example, a derivative of a Tetrahymena L-19 EVS RNA is sometimes utilized in which the nucleotide sequence ofthe active site is complementary to the nucleotide sequence to be cleaved in a mRNA (see e.g., Cech et al. U.S. Patent No. 4,987,071; and Cech et al. U.S. Patent No. 5,116,742). Also, target mRNA sequences can be used to select a catalytic RNA having a specific ribonuclease activity from a pool of RNA molecules (see e.g., Bartel & Szostak, Science 261: 1411-1418 (1993)). [0133] Breast cancer directed molecules include in certain embodiments nucleic acids that can form triple helix stractures with a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 nucleotide sequence or a substantially identical sequence thereof, especially one that includes a regulatory region that controls expression of a polypeptide. Gene expression can be inhibited by targeting nucleotide sequences complementary to the regulatory region of a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCH 5209 or HRMT1L3 nucleotide sequence or a substantially identical sequence (e.g., promoter and/or enhancers) to form triple helical stractures that prevent transcription of a gene in target cells (see e.g., Helene, Anticancer Drag Des. 6(6): 569-84 (1991); Helene et al, Ann. N.Y. Acad. Sci. 660: 27-36 (1992); and Maher, Bioassays 14(12): 807-15 (1992). Potential sequences that can be targeted for triple helix formation can be increased by creating a so-called "switchback" nucleic acid molecule. Switchback molecules are synthesized in an alternating 5 '-3', 3 '-5' manner, such that they base pair with first one strand of a duplex and then the other, eliminating the necessity for a sizeable stretch of either purines or pyrimidines to be present on one strand of a duplex. [0134] Breast cancer directed molecules include RNAi and siRNA nucleic acids. Gene expression may be inhibited by the introduction of double-stranded RNA (dsRNA), which induces potent and specific gene silencing, a phenomenon called RNA interference or RNAi. See, e.g., Fire et al, US Patent Number 6,506,559; Tuschl et al. PCT International Publication No. WO 01/75164; Kay et al. PCT International Publication No. WO 03/010180A1; or Bosher JM, Labouesse, Nat Cell Biol 2000 Feb;2(2):E31-6. This process has been improved by decreasing the size ofthe double- stranded RNA to 20-24 base pairs (to create small-interfering RNAs or siRNAs) that "switched off genes in mammalian cells without initiating an acute phase response, i.e, a host defense mechanism that often results in cell death (see, e.g., Caplen et al. Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9742-7 and Elbasbir et al. Methods 2002 Feb;26(2):199-213). There is increasing evidence of post-transcriptional gene silencing by RNA interference (RNAi) for inhibiting targeted expression in mammalian cells at the mRNA level, in human cells. There is additional evidence of effective methods for inhibiting the proliferation and migration of tumor cells in human patients, and for inhibiting metastatic cancer development (see, e.g., U.S. Patent Application No. US2001000993183; Caplen et al. Proc Natl Acad Sci U S A; and Abderrahmani et al. Mol Cell Biol 2001 Nov21(21):7256-67). [0135] An "siRNA" or "RNAi" refers to a nucleic acid that forms a double stranded RNA and has the ability to reduce or inhibit expression of a gene or target gene when the siRNA is delivered to or expressed in the same cell as the gene or target gene. "siRNA" refers to short double-stranded RNA formed by the complementary strands. Complementary portions ofthe siRNA that hybridize to form the double stranded molecule often have substantial or complete identity to the target molecule sequence. In one embodiment, an siRNA refers to a nucleic acid that has substantial or complete identity to a target gene and forms a double stranded siRNA. [0136] When designing the siRNA molecules, the targeted region often is selected from a given DNA sequence beginning 50 to 100 nucleotides downstream ofthe start codon. See, e.g.,

Elbasbir et al,. Methods 26:199-213 (2002). Initially, 5' or 3' UTRs and regions nearby the start codon were avoided assuming that UTR-binding proteins and/or translation initiation complexes may interfere with binding ofthe siRNP or RISC endonuclease complex. Sometimes regions ofthe target 23 nucleotides in length conforming to the sequence motif AA(N19)TT (N, an nucleotide), and regions with approximately 30% to 70% G/C-content (often about 50% G/C-content) often are selected. If no suitable sequences are found, the search often is extended using the motif NA(N21). The sequence ofthe sense siRNA sometimes corresponds to (N19) TT or N21 (position 3 to 23 of the 23-nt motif), respectively. In the latter case, the 3' end ofthe sense siRNA often is converted to TT. The rationale for this sequence conversion is to generate a symmetric duplex with respect to the sequence composition ofthe sense and antisense 3' overhangs. The antisense siRNA is synthesized as the complement to position 1 to 21 ofthe 23-nt motif. Because position 1 ofthe 23- nt motif is not recognized sequence-specifically by the antisense siRNA, the 3 '-most nucleotide residue ofthe antisense siRNA can be chosen deliberately. However, the penultimate nucleotide of the antisense siRNA (complementary to position 2 ofthe 23-nt motif) often is complementary to the targeted sequence. For simplifying chemical synthesis, TT often is utilized. siRNAs corresponding to the target motif NAR(N17)YNN, where R is purine (A,G) and Y is pyrimidine (C,U), often are selected. Respective 21 nucleotide sense and antisense siRNAs often begin with a purine nucleotide and can also be expressed from pol HI expression vectors without a change in targeting site. Expression of RNAs from pol HE promoters often is efficient when the first transcribed nucleotide is a purine. [0137] The sequence ofthe siRNA can correspond to the full length target gene, or a subsequence thereof. Often, the siRNA is about 15 to about 50 nucleotides in length (e.g., each complementary sequence ofthe double stranded siRNA is 15-50 nucleotides in length, and the double stranded siRNA is about 15-50 base pairs in length, sometimes about 20-30 nucleotides in length or about 20-25 nucleotides in length, e.g., 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, or 30 nucleotides in length. The siRNA sometimes is about 21 nucleotides in length. Methods of using siRNA are well known in the art, and specific siRNA molecules may be purchased from a number of companies including Dharmacon Research, Luc. [0138] Antisense, ribozyme, RNAi and siRNA nucleic acids can be altered to form modified nucleic acid molecules. The nucleic acids can be altered at base moieties, sugar moieties or phosphate backbone moieties to improve stability, hybridization, or solubility ofthe molecule. For example, the deoxyribose phosphate backbone of nucleic acid molecules can be modified to generate peptide nucleic acids (see Hyrup et al, Bioorganic & Medicinal Chemistry 4 (1): 5-23

(1996)). As used herein, the terms "peptide nucleic acid" or "PNA" refers to a nucleic acid mimic such as a DNA mimic, in which the deoxyribose phosphate backbone is replaced by a pseudopeptide backbone and only the four natural nucleobases are retained. The neutral backbone of a PNA can allow for specific hybridization to DNA and RNA under conditions of low ionic strength. Synthesis of PNA oligomers can be performed using standard solid phase peptide synthesis protocols as described, for example, in Hyrup et al, (1996) supra and Perry-O'Keefe et al, Proc. Natl. Acad. Sci. 93: 14670-675 (1996). [0139] PNA nucleic acids can be used in prognostic, diagnostic, and therapeutic applications. For example, PNAs can be used as antisense or antigene agents for sequence-specific modulation of gene expression by, for example, inducing transcription or translation arrest or inhibiting replication. PNA nucleic acid molecules can also be used in the analysis of single base pair mutations in a gene, (e.g., by PNA-directed PCR clamping); as "artificial restriction enzymes" when used in combination with other enzymes, (e.g., SI nucleases (Hyrup (1996) supra)); or as probes or primers for DNA sequencing or hybridization (Hyrup et al, (1996) supra; Perry-O'Keefe supra). [0140] Lu other embodiments, oligonucleotides may include other appended groups such as peptides (e.g., for targeting host cell receptors in vivo), or agents facilitating transport across cell membranes (see e.g., Letsinger et al, Proc. Natl. Acad. Sci. USA 86: 6553-6556 (1989); Lemaitre et al, Proc. Natl. Acad. Sci. USA 84: 648-652 (1987); PCT Publication No. W088/09810) or the blood-brain barrier (see, e.g., PCT Publication No. W089/10134). En addition, oligonucleotides can be modified with hybridization-triggered cleavage agents (See, e.g., Krol et al, Bio-Techniques 6: 958-976 (1988)) or intercalating agents. (See, e.g., Zon, Pharm. Res. 5: 539-549 (1988) ). To this end, the oligonucleotide may be conjugated to another molecule, (e.g., a peptide, hybridization triggered cross-linking agent, transport agent, or hybridization-triggered cleavage agent). [0141] Also included herein are molecular beacon oligonucleotide primer and probe molecules having one or more regions complementary to a nucleotide sequence of SEQ ED NO: 1-12 or a substantially identical sequence thereof, two complementary regions one having a fluorophore and one a quencher such that the molecular beacon is useful for quantifying the presence ofthe nucleic acid in a sample. Molecular beacon nucleic acids are described, for example, in Lizardi et al, U.S. Patent No. 5,854,033; Nazarenko et al, U.S. Patent No. 5,866,336, and Livak et al, U.S. Patent 5,876,930.

Antibodies [0142] The term "antibody" as used herein refers to an immunoglobulin molecule or immunologically active portion thereof, i.e, an antigen-binding portion. Examples of immunologically active portions of immunoglobulin molecules include F(ab) and F(ab')₂ fragments which can be generated by treating the antibody with an enzyme such as pepsin. An antibody sometimes is a polyclonal, monoclonal, recombinant (e.g., a chimeric or humanized), fully human, non-human (e.g., murine), or a single chain antibody. An antibody may have effector function and can fix complement, and is sometimes coupled to a toxin or imaging agent. An example of an antibody that specifically interacts with a SERPINA5 polypeptide/urokinase-plasminogen activator complex described in JP62253382. [0143] A full-length polypeptide or antigenic peptide fragment encoded by a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 nucleotide sequence can be used as an immunogen or can be used to identify antibodies made with other immunogens, e.g., cells, membrane preparations, and the like. An antigenic peptide often includes at least 8 amino acid residues ofthe amino acid sequences encoded by a nucleotide sequence of SEQ ED NO: 1-12, or substantially identical sequence thereof, and encompasses an epitope. Antigenic peptides sometimes include 10 or more amino acids, 15 or more amino acids, 20 or more amino acids, or 30 or more amino acids. Hydrophilic and hydrophobic fragments of polypeptides sometimes are used as immunogens. [0144] Epitopes encompassed by the antigenic peptide are regions located on the surface ofthe polypeptide (e.g., hydrophilic regions) as well as regions with high antigenicity. For example, an Emini surface probability analysis ofthe human polypeptide sequence can be used to indicate the regions that have a particularly high probability of being localized to the surface ofthe polypeptide and are thus likely to constitute surface residues useful for targeting antibody production. The antibody may bind an epitope on any domain or region on polypeptides described herein. [0145] Also, chimeric, humanized, and completely human antibodies are useful for applications which include repeated administration to subjects. Chimeric and humanized monoclonal antibodies, comprising both human and non-human portions, can be made using standard recombinant DNA techniques. Such chimeric and humanized monoclonal antibodies can be produced by recombinant DNA techniques known in the art, for example using methods described in Robinson et al International Application No. PCT US86/02269; Akira, et al European Patent Application 184,187; Taniguchi, M, European Patent Application 171,496; Morrison et al European Patent Application 173,494; Neuberger et al PCT International Publication No. WO 86/01533; Cabilly et al U.S. Patent No. 4,816,567; Cabilly et al European Patent Application 125,023; Better et al, Science 240: 1041-1043 (1988); Liu et al, Proc. Natl. Acad. Sci. USA 84: 3439.3443 (1987); Liu et al, J. Immunol. 139: 3521-3526 (1987); Sun et al, Proc. Natl. Acad. Sci. USA 84: 214-218 (1987); Nishimura et al, Cane. Res. 47: 999-1005 (1987); Wood et al, Nature 314: 446-449 (1985); and Shaw et al, J. Natl. Cancer Lust. 80: 1553-1559 (1988); Morrison, S. L, Science 229: 1202-1207 (1985); Oi et al, BioTechniques 4: 214 (1986); Winter U.S. Patent 5,225,539; Jones et al, Nature 321 : 552-525 (1986); Verhoeyan et al, Science 239: 1534; and Beidler et al, J. Immunol. 141: 4053-4060 (1988). [0146] Completely human antibodies are particularly desirable for therapeutic treatment of human patients. Such antibodies can be produced using transgenic mice that are incapable of expressing endogenous immunoglobulin heavy and light chains genes, but which can express human heavy and light chain genes. See, for example, Lonberg and Huszar, Ent. Rev. Immunol. 13: 65-93 (1995); and U.S. Patent Nos. 5,625,126; 5,633,425; 5,569,825; 5,661,016; and 5,545,806. En addition, companies such as Abgenix, Inc. (Fremont, CA) and Medarex, Luc. (Princeton, NJ), can be engaged to provide human antibodies directed against a selected antigen using technology similar to that described above. Completely human antibodies that recognize a selected epitope also can be generated using a technique referred to as "guided selection." In this approach a selected non- human monoclonal antibody (e.g., a murine antibody) is used to guide the selection of a completely human antibody recognizing the same epitope. This technology is described for example by Jespers et al, Bio/Technology 12: 899-903 (1994). [0147] Antibody can be a single chain antibody. A single chain antibody (scFV) can be engineered (see, e.g., Colcher et al, Ann. N Y Acad. Sci. 880: 263-80 (1999); and Reiter, Clin. Cancer Res. 2: 245-52 (1996)). Single chain antibodies can be dimerized or multimerized to generate multivalent antibodies having specificities for different epitopes ofthe same target polypeptide. [0148] Antibodies also may be selected or modified so that they exhibit reduced or no ability to bind an Fc receptor. For example, an antibody may be an isotype or subtype, fragment or other mutant, which does not support binding to an Fc receptor (e.g., it has a mutagenized or deleted Fc receptor binding region). [0149] Also, an antibody (or fragment thereof) may be conjugated to a therapeutic moiety such as a cytotoxin, a therapeutic agent or a radioactive metal ion. A cytotoxin or cytotoxic agent includes any agent that is detrimental to cells. Examples include taxol, cytochalasin B, gramicidin D, ethidium bromide, emetine, mitomycin, etoposide, tenoposide, vincristine, vinblastine, colchicin, doxorabicin, daunorabicin, dihydroxy anthracin dione, mitoxantrone, mithramycin, actinomycin D, 1 dehydrotestosterone, glucocorticoids, procaine, tetracaine, lidocaine, propranolol, and puromycin and analogs or homologs thereof. Therapeutic agents include, but are not limited to, antimetabolites (e.g., methotrexate, 6-mercaptopurine, 6-thioguanine, cytarabine, 5 -fluorouracil decarbazine), alkylating agents (e.g., mecUorethamine, thiotepa chlorambucil, melphalan, carmustine (BCNU) and lomustine (CCNU), cyclophosphamide, busulfan, dibromomannitol, streptozotocin, mitomycin C, and cis-dichlorodiamine platinum (H) (DDP) cisplatin), anthracyclines (e.g., daunorabicin (formerly daunomycin) and doxorabicin), antibiotics (e.g., dactinomycin (formerly actinomycin), bleomycin, mithramycin, and anthramycin (AMC)), and anti- mitotic agents (e.g., vincristine and vinblastine). [0150] Antibody conjugates can be used for modifying a given biological response. For example, the drug moiety may be a protein or polypeptide possessing a desired biological activity.

Such proteins may include, for example, a toxin such as abrin, ricin A, pseudomonas exotoxin, or diphtheria toxin; a polypeptide such as tumor necrosis factor, ?-interferon, a-interferon, nerve growth factor, platelet derived growth factor, tissue plasminogen activator; or, biological response modifiers such as, for example, lymphokines, interleukin-1 ("EL-1"), interleukin-2 ("EL-2"), interleukin-6 ("EL-6"), granulocyte macrophage colony stimulating factor ("GM-CSF"), granulocyte colony stimulating factor ("G-CSF"), or other growth factors. Also, an antibody can be conjugated to a second antibody to form an antibody heteroconjugate as described by Segal in U.S. Patent No. 4,676,980, for example. [0151] An antibody (e.g. , monoclonal antibody) can be used to isolate target polypeptides by standard techniques, such as affinity chromatography or immunoprecipitation. Moreover, an antibody can be used to detect a target polypeptide (e.g., in a cellular lysate or cell supernatant) in order to evaluate the abundance and pattern of expression ofthe polypeptide. Antibodies can be used diagnostically to monitor polypeptide levels in tissue as part of a clinical testing procedure, e.g. , to determine the efficacy of a given treatment regimen. Detection can be facilitated by coupling (i.e, physically linking) the antibody to a detectable substance (i.e, antibody labeling). Examples of detectable substances include various enzymes, prosthetic groups, fluorescent materials, luminescent materials, bioluminescent materials, and radioactive materials. Examples of suitable enzymes include horseradish peroxidase, alkaline phosphatase, β-galactosidase, or acetylcholinesterase; examples of suitable prosthetic group complexes include streptavidin/biotin and avidin/biotin; examples of suitable fluorescent materials include umbelliferone, fluorescein, fluorescein isothiocyanate, rhodamine, dichlorotriazinylamine fluorescein, dansyl chloride or phycoerythrin; an example of a luminescent material includes luminol; examples of bioluminescent materials include luciferase, luciferin, and aequorin, and examples of suitable radioactive material include I, I, S or H. Also, an antibody can be utilized as a test molecule for determining whether it can treat breast cancer, and as a therapeutic for administration to a subject for treating breast cancer. [0152] An antibody can be made by immunizing with a purified antigen, or a fragment thereof, e.g., a fragment described herein, a membrane associated antigen, tissues, e.g., crude tissue preparations, whole cells, preferably living cells, lysed cells, or cell fractions. [0153] Included herein are antibodies which bind only a native polypeptide, only denatured or otherwise non-native polypeptide, or which bind both, as well as those having linear or conformational epitopes. Conformational epitopes sometimes can be identified by selecting antibodies that bind to native but not denatured polypeptide. Also featured are antibodies that specifically bind to a polypeptide variant associated with breast cancer.

Screening Assays [0154] Featured herein are methods for identifying a candidate therapeutic for treating breast cancer. The methods comprise contacting a test molecule with a target molecule in a system. A "target molecule" as used herein refers to a nucleic acid of SEQ ED NO: 1-12, a substantially identical nucleic acid thereof, or a fragment thereof, and an encoded polypeptide ofthe foregoing. The method also comprises determining the presence or absence of an interaction between the test molecule and the target molecule, where the presence of an interaction between the test molecule and the nucleic acid or polypeptide identifies the test molecule as a candidate breast cancer therapeutic. The interaction between the test molecule and the target molecule may be quantified. [0155] Test molecules and candidate therapeutics include, but are not limited to, compounds, antisense nucleic acids, siRNA molecules, ribozymes, polypeptides or proteins encoded by a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 nucleic acids, or a substantially identical sequence or fragment thereof, and immunotherapeutics (e.g., antibodies and HLA- presented polypeptide fragments). A test molecule or candidate therapeutic may act as a modulator of target molecule concentration or target molecule function in a system. A "modulator" may agonize (i.e., up-regulates) or antagonize (i.e., down-regulates) a target molecule concentration partially or completely in a system by affecting such cellular functions as DNA replication and/or DNA processing (e.g., DNA methylation or DNA repair), RNA transcription and or RNA processing (e.g. , removal of intronic sequences and or translocation of spliced mRNA from the nucleus), polypeptide production (e.g., translation ofthe polypeptide from mRNA), and/or polypeptide post-translational modification (e.g., glycosylation, phosphorylation, and proteolysis of pro-polypeptides). A modulator may also agonize or antagonize a biological function of a target molecule partially or completely, where the function may include adopting a certain structural conformation, interacting with one or more binding partners, ligand binding, catalysis (e.g., phosphorylation, dephosphorylation, hydrolysis, methylation, and isomerization), and an effect upon a cellular event (e.g., effecting progression of breast cancer). Examples of assays useful for screening GRTN3A and PFTKl modulators, for example, are described in US2000200034778-? 1; US6130058; Rzeski W. et al, Proc. Natl. Acad Sci. USA 11:6312-1 (May 1998) Epub May 2001; and W09933962-A1; Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai), 34(4):520-5 (July 2002); Hashida T et al Endocrinology 143(7):2808-11 (July 2002). [0156] As used herein, the term "system" refers to a cell free in vitro environment and a cell- based environment such as a collection of cells, a tissue, an organ, or an organism. A system is "contacted" with a test molecule in a variety of manners, including adding molecules in solution and allowing them to interact with one another by diffusion, cell injection, and any administration routes in an animal. As used herein, the term "interaction" refers to an effect of a test molecule on test molecule, where the effect sometimes is binding between the test molecule and the target molecule, and sometimes is an observable change in cells, tissue, or organism. [0157] There are many standard methods for detecting the presence or absence of an interaction between a test molecule and a target molecule. For example, titrametric, acidimetric, radiometric, NMR, monolayer, polarographic, spectrophotometric, fluorescent, and ESR assays probative of a target molecule interaction may be utilized. [0158] En general, an interaction can be determined by labeling the test molecule and/or the SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 molecule, where the label is covalently or non-covalently attached to the test molecule or SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 molecule. The label is sometimes a radioactive molecule such as ¹²⁵I, ¹³¹1, ³⁵S or ³H, which can be detected by direct counting of radioemission or by scintillation counting. Also, enzymatic labels such as horseradish peroxidase, alkaline phosphatase, or luciferase may be utilized where the enzymatic label can be detected by determining conversion of an appropriate substrate to product. Also, presence or absence of an interaction can be determined without labeling. For example, a microphysiometer (e.g, Cytosensor) is an analytical instrument that measures the rate at which a cell acidifies its environment using a light-addressable potentiometric sensor (LAPS). Changes in this acidification rate can be used as an indication of an interaction between a test molecule and SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 (McConnell, H. M. et al. Science 257: 1906-1912 (1992)). [0159] In cell-based systems, cells typically include a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 nucleic acid or polypeptide or variants thereof and are often of mammalian origin, although the cell can be of any origin. Whole cells, cell homogenates, and cell fractions (e.g, cell membrane fractions) can be subjected to analysis. Where interactions between a test molecule with a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide or variant thereof are monitored, soluble and or membrane bound forms ofthe polypeptide or variant may be utilized. Where membrane-bound forms ofthe polypeptide are used, it may be desirable to utilize a solubilizing agent. Examples of such solubilizing agents include non-ionic detergents such as n-octylglucoside, n-dodecylglucoside, n-dodecylmaltoside, octanoyl-N- methylglucamide, decanoyl-N-methylglucamide, Triton^® X-100, Triton^® X-l 14, Thesit^®, Isotridecypoly(ethylene glycol ether)n, 3-[(3-cholamidopropyl)onnethylamminio]-l -propane sulfonate (CHAPS), 3-[(3-cholamidopropyl)ώmethylamminio]-2-hydroxy-l -propane sulfonate (CHAPSO), or N-dodecyl-N,N-dimethyl-3-ammonio-l -propane sulfonate. [0160] An interaction between two molecules also can be detected by monitoring fluorescence energy transfer (FET) (see, for example, Lakowicz et al, U.S. Patent No. 5,631,169; Stavrianopoulos et al. U.S. Patent No. 4,868,103). A fluorophore label on a first, "donor" molecule is selected such that its emitted fluorescent energy will be absorbed by a fluorescent label on a second, "acceptor" molecule, which in turn is able to fluoresce due to the absorbed energy. Alternately, the "donor" polypeptide molecule may simply utilize the natural fluorescent energy of tryptophan residues. Labels are chosen that emit different wavelengths of light, such that the

"acceptor" molecule label may be differentiated from that ofthe "donor". Since the efficiency of energy transfer between the labels is related to the distance separating the molecules, the spatial relationship between the molecules can be assessed. En a situation in which binding occurs between the molecules, the fluorescent emission ofthe "acceptor" molecule label in the assay should be maximal. An FET binding event can be conveniently measured through standard fluorometric detection means well known in the art (e.g, using a fluorimeter). [0161] Lu another embodiment, determiriing the presence or absence of an interaction between a test molecule and a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 molecule can be effected by using real-time Biomolecular Interaction Analysis (BIA) (see, e.g, Sjolander & Urbaniczk, Anal. Chem. 63: 2338-2345 (1991) and Szabo et al, Curr. Opin. Struct. Biol. 5: 699- 705 (1995)). "Surface plasmon resonance" or "BIA" detects biospecific interactions in real time, without labeling any ofthe interactants (e.g, BIAcore). Changes in the mass at the binding surface (indicative of a binding event) result in alterations ofthe refractive index of light near the surface (the optical phenomenon of surface plasmon resonance (SPR)), resulting in a detectable signal which can be used as an indication of real-time reactions between biological molecules. [0162] Lu another embodiment, the SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 molecule or test molecules are anchored to a solid phase. The SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 molecule/test molecule complexes anchored to the solid phase can be detected at the end ofthe reaction. The target SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 molecule is often anchored to a solid surface, and the test molecule, which is not anchored, can be labeled, either directly or indirectly, with detectable labels discussed herein. [0163] It may be desirable to immobilize a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 molecule, an anti-SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 antibody, or test molecules to facilitate separation of complexed from uncomplexed forms of SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 molecules and test molecules, as well as to accommodate automation ofthe assay. Binding of a test molecule to a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 molecule can be accomplished in any vessel suitable for containing the reactants. Examples of such vessels include microtiter plates, test tubes, and micro-centrifuge tubes. En one embodiment, a fusion polypeptide can be provided which adds a domain that allows a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 molecule to be bound to a matrix. For example, glutatbione-S-transferase/SPt T E'₎ GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 fusion polypeptides or glutathione-S- transferase/target fusion polypeptides can be adsorbed onto glutathione sepharose beads (Sigma Chemical, St. Louis, MO) or glutathione derivitized microtiter plates, which are then combined with the test compound or the test compound and either the non-adsorbed target polypeptide or

SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide, and the mixture incubated under conditions conducive to complex formation (e.g, at physiological conditions for salt and pH). Following incubation, the beads or microtiter plate wells are washed to remove any unbound components, the matrix immobilized in the case of beads, complex determined either directly or indirectly, for example, as described above. Alternatively, the complexes can be dissociated from the matrix, and the level oi SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 binding or activity determined using standard techniques. [0164] Other techniques for immobilizing a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 molecule on matrices include using biotin and streptavidin. For example, biotinylated SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide or target molecules can be prepared from biotin-NHS (N-hydroxy-succinimide) using techniques known in the art (e.g, biotinylation kit, Pierce Chemicals, Rockford, EL), and immobilized in the wells of streptavidin-coated 96 well plates (Pierce Chemical). [0165] En order to conduct the assay, the non-immobilized component is added to the coated surface containing the anchored component. After the reaction is complete, unreacted components are removed (e.g, by washing) under conditions such that any complexes formed will remain immobilized on the solid surface. The detection of complexes anchored on the solid surface can be accomplished in a number of ways. Where the previously non-immobilized component is pre- labeled, the detection of label immobilized on the surface indicates that complexes were formed. Where the previously non-immobilized component is not pre-labeled, an indirect label can be used to detect complexes anchored on the surface; e.g, using a labeled antibody specific for the immobilized component (the antibody, in turn, can be directly labeled or indirectly labeled with, e.g, a labeled anti-Ig antibody). [0166] En one embodiment, this assay is performed utilizing antibodies reactive with SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide or test molecules but which do not interfere with binding ofthe SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide to its test molecule. Such antibodies can be derivitized to the wells ofthe plate, and unbound target or SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide trapped in the wells by antibody conjugation. Methods for detecting such complexes, in addition to those described above for the GST-immobilized complexes, include immunodetection of complexes using antibodies reactive with the SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide or target molecule, as well as enzyme-linked assays which rely on detecting an enzymatic activity associated with the SPUVE, GRIN3A, PFTKl, SERPINA5, LOCH 5209 or HRMT1L3 polypeptide or test molecule. [0167] Alternatively, cell free assays can be conducted in a liquid phase. En such an assay, the reaction products are separated from unreacted components, by any of a number of standard techniques, including but not limited to: differential centrifugation (see, for example, Rivas, G, and Minton, A. P, Trends Biochem Sci Aug; 18(8): 284-7 (1993)); chromatography (gel filtration chromatography, ion-exchange chromatography); electrophoresis (see, e.g, Ausubel et al, eds. Current Protocols in Molecular Biology , J. Wiley: New York (1999)); and immunoprecipitation (see, for example, Ausubel, F. et al, eds. Current Protocols in Molecular Biology , J. Wiley: New York (1999)). Such resins and chromatographic techniques are known to one skilled in the art (see, e.g, Heegaard, J Mol. Recognit. Winter; 11(1-6): 141-8 (1998); Hage & Tweed, J. Chromatogr. B Biomed. Sci. Appl. Oct 10; 699 (1-2): 499-525 (1997)). Further, fluorescence energy transfer may also be conveniently utilized, as described herein, to detect binding without further purification of the complex from solution. [0168] Lu another embodiment, modulators of SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 expression are identified. For example, a cell or cell free mixture is contacted with a candidate compound and the expression of SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 mRNA or polypeptide evaluated relative to the level of expression of SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 mRNA or polypeptide in the absence ofthe candidate compound. When expression of SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 mRNA or polypeptide is greater in the presence ofthe candidate compound than in its absence, the candidate compound is identified as a stimulator of SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 mRNA or polypeptide expression. Alternatively, when expression of SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 mRNA or polypeptide is less (statistically significantly less) in the presence ofthe candidate compound than in its absence, the candidate compound is identified as an inhibitor of SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 mRNA or polypeptide expression. The level of SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 mRNA or polypeptide expression can be determined by methods described herein for detecting SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 mRNA or polypeptide. [0169] In another embodiment, binding partners that interact with a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 molecule are detected. The SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 molecules can interact with one or more cellular or extracellular macromolecules, such as polypeptides, in vivo, and these molecules that interact with SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 molecules are referred to herein as "binding partners." Molecules that disrupt such interactions can be useful in regulating the activity ofthe target gene product. Such molecules can include, but are not limited to molecules such as antibodies, peptides, and small molecules. Target genes/products for use in this embodiment often are the SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 genes herein identified. Lu an alternative embodiment, provided is a method for determining the ability of the test compound to modulate the activity of a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide through modulation ofthe activity of a downstream effector of a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 target molecule. For example, the activity ofthe effector molecule on an appropriate target can be determined, or the binding ofthe effector to an appropriate target can be determined, as previously described. [0170] To identify compounds that interfere with the interaction between the target gene product and its cellular or extracellular binding partner(s), e.g, a substrate, a reaction mixture containing the target gene product and the binding partner is prepared, under conditions and for a time sufficient, to allow the two products to form complex. Lu order to test an inhibitory agent, the reaction mixture is provided in the presence and absence ofthe test compound. The test compound can be initially included in the reaction mixture, or can be added at a time subsequent to the addition ofthe target gene and its cellular or extracellular binding partner. Control reaction mixtures are incubated without the test compound or with a placebo. The formation of any complexes between the target gene product and the cellular or extracellular binding partner is then detected. The formation of a complex in the control reaction, but not in the reaction mixture containing the test compound, indicates that the compound interferes with the interaction ofthe target gene product and the interactive binding partner. Additionally, complex formation within reaction mixtures containing the test compound and normal target gene product can also be compared to complex formation within reaction mixtures containing the test compound and mutant target gene product. This comparison can be important in those cases where it is desirable to identify compounds that disrupt interactions of mutant but not normal target gene products. [0171] These assays can be conducted in a heterogeneous or homogeneous format. Heterogeneous assays involve anchoring either the target gene product or the binding partner onto a solid phase, and detecting complexes anchored on the solid phase at the end ofthe reaction. Lu homogeneous assays, the entire reaction is carried out in a liquid phase. En either approach, the order of addition of reactants can be varied to obtain different information about the compounds being tested. For example, test compounds that interfere with the interaction between the target gene products and the binding partners, e.g, by competition, can be identified by conducting the reaction in the presence ofthe test substance. Alternatively, test compounds that disrupt preformed complexes, e.g, compounds with higher binding constants that displace one ofthe components from the complex, can be tested by adding the test compound to the reaction mixture after complexes have been formed. The various formats are briefly described below. [0172] Lu a heterogeneous assay system, either the target gene product or the interactive cellular or extracellular binding partner, is anchored onto a solid surface (e.g, a microtiter plate), while the non-anchored species is labeled, either directly or indirectly. The anchored species can be immobilized by non-covalent or covalent attachments. Alternatively, an immobilized antibody specific for the species to be anchored can be used to anchor the species to the solid surface. [0173] En order to conduct the assay, the partner ofthe immobilized species is exposed to the coated surface with or without the test compound. After the reaction is complete, unreacted components are removed (e.g, by washing) and any complexes formed will remain immobilized on the solid surface. Where the non-immobilized species is pre-labeled, the detection of label immobilized on the surface indicates that complexes were formed. Where the non-immobilized species is not pre-labeled, an indirect label can be used to detect complexes anchored on the surface; e.g, using a labeled antibody specific for the initially non-immobilized species (the antibody, in turn, can be directly labeled or indirectly labeled with, e.g, a labeled anti-Ig antibody). Depending upon the order of addition of reaction components, test compounds that inhibit complex formation or that disrupt preformed complexes can be detected. [0174] Alternatively, the reaction can be conducted in a liquid phase in the presence or absence ofthe test compound, the reaction products separated from unreacted components, and complexes detected; e.g, using an immobilized antibody specific for one ofthe binding components to anchor any complexes formed in solution, and a labeled antibody specific for the other partner to detect anchored complexes. Again, depending upon the order of addition of reactants to the liquid phase, test compounds that inhibit complex or that disrupt preformed complexes can be identified. [0175] In an alternate embodiment, a homogeneous assay can be used. For example, a preformed complex ofthe target gene product and the interactive cellular or extracellular binding partner product is prepared in that either the target gene products or their binding partners are labeled, but the signal generated by the label is quenched due to complex formation (see, e.g, U.S. Patent No. 4,109,496 that utilizes this approach for immunoassays). The addition of a test substance that competes with and displaces one ofthe species from the preformed complex will result in the generation of a signal above background. Lu this way, test substances that disrupt target gene product-binding partner interaction can be identified. [0176] Also, binding partners of SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 molecules can be identified in a two-hybrid assay or three-hybrid assay (see, e.g, U.S. Patent No. 5,283,317; Zervos et al. Cell 72:223-232 (1993); Madura et al, J. Biol. Chem. 268: 12046-12054 (1993); Bartel et al, Biotechniques 14: 920-924 (1993); Iwabuchi et al, Oncogene 8: 1693-1696 (1993); and Brent WO94/10300), to identify other polypeptides, which bind to or interact with SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 ("SPUVE, GRIN3A, PFTKl, polypeptides" or "SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMTlL3-bp") and are involved in SPUVE, GRIN3A, PFTKl, SERPINA5, LOCH 5209 or HRMT1L3 activity. Such SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3-ΌΌS can be activators or inhibitors of signals by the SPUVE, GRIN3A,

PFTKl, SERPINA5, LOCH 5209 or HRMT1L3 polypeptides or SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 targets as, for example, downstream elements of a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 -mediated signaling pathway. [0177] A two-hybrid system is based on the modular nature of most transcription factors, which consist of separable DNA-binding and activation domains. Briefly, the assay utilizes two different DNA constructs. In one construct, the gene that codes for a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide is fused to a gene encoding the DNA binding domain of a known transcription factor (e.g, GAL-4). n the other construct, a DNA sequence, from a library of DNA sequences, that encodes an unidentified polypeptide ("prey" or "sample") is fused to a gene that codes for the activation domain ofthe known transcription factor. (Alternatively the: SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide can be the fused to the activator domain.) If the "bait" and the "prey" polypeptides are able to interact, in vivo, forming a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3- dependent complex, the DNA-binding and activation domains ofthe transcription factor are brought into close proximity. This proximity allows transcription of a reporter gene (e.g, LacZ) which is operably linked to a transcriptional regulatory site responsive to the transcription factor. Expression ofthe reporter gene can be detected and cell colonies containing the functional transcription factor can be isolated and used to obtain the cloned gene which encodes the polypeptide which interacts with the SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide. [0178] Candidate therapeutics for treating breast cancer are identified from a group of test molecules that interact with a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 nucleic acid or polypeptide. Test molecules are normally ranked according to the degree with which they interact or modulate (e.g, agonize or antagonize) DNA replication and/or processing, RNA transcription and/or processing, polypeptide production and/or processing, and/or function of SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 molecules, for example, and then top ranking modulators are selected. Lu a preferred embodiment, the candidate therapeutic (i.e, test molecule) acts as a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 antagonist. Also, pharmacogenomic information described herein can determine the rank of a modulator. Candidate therapeutics typically are formulated for administration to a subject.

Therapeutic Treatments [0179] Formulations or pharmaceutical compositions typically include in combination with a pharmaceutically acceptable carrier, a compound, an antisense nucleic acid, a ribozyme, an antibody, a binding partner that interacts with a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide, a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 nucleic acid, or a fragment thereof. The formulated molecule may be one that is identified by a screening method described above. Also, formulations may comprise a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide or fragment thereof. As used herein, the term "pharmaceutically acceptable carrier" includes solvents, dispersion media, coatings, antibacterial and antifungal agents, isotonic and absoφtion delaying agents, and the like, compatible with pharmaceutical aαniinistration. Supplementary active compounds can also be incoφorated into the compositions. [0180] A pharmaceutical composition is formulated to be compatible with its intended route of administration. Examples of routes of administration include parenteral, e.g, intravenous, intradermal, subcutaneous, oral (e.g, inhalation), transdermal (topical), transmucosal, and rectal administration. Solutions or suspensions used for parenteral, intradermal, or subcutaneous application can include the following components: a sterile diluent such as water for injection, saline solution, fixed oils, polyethylene glycols, glycerin, propylene glycol or other synthetic solvents; antibacterial agents such as benzyl alcohol or methyl parabens; antioxidants such as ascorbic acid or sodium bisulfite; chelating agents such as ethylenediaminetetraacetic acid; buffers such as acetates, citrates or phosphates and agents for the adjustment of tonicity such as sodium chloride or dextrose. pH can be adjusted with acids or bases, such as hydrochloric acid or sodium hydroxide. The parenteral preparation can be enclosed in ampoules, disposable syringes or multiple dose vials made of glass or plastic. [0181] Oral compositions generally include an inert diluent or an edible carrier. For the puφose of oral therapeutic administration, the active compound can be incoφorated with excipients and used in the form of tablets, troches, or capsules, e.g, gelatin capsules. Oral compositions can also be prepared using a fluid carrier for use as a mouthwash. Pharmaceutically compatible binding agents, and/or adjuvant materials can be included as part ofthe composition. The tablets, pills, capsules, troches and the like can contain any ofthe following ingredients, or compounds of a similar nature: a binder such as microcrystalline cellulose, gum tragacanth or gelatin; an excipient such as starch or lactose, a disintegrating agent such as alginic acid, Primogel, or corn starch; a lubricant such as magnesium stearate or Sterotes; a glidant such as colloidal silicon dioxide; a sweetening agent such as sucrose or saccharin; or a flavoring agent such as peppermint, methyl salicylate, or orange flavoring. [0182] Pharmaceutical compositions suitable for injectable use include sterile aqueous solutions (where water soluble) or dispersions and sterile powders for the extemporaneous preparation of sterile injectable solutions or dispersion. For intravenous administration, suitable carriers include physiological saline, bacteriostatic water, Cremophor EL™ (BASF, Parsippany,

NJ) or phosphate buffered saline (PBS). In all cases, the composition must be sterile and should be fluid to the extent that easy syringability exists. It should be stable under the conditions of manufacture and storage and must be preserved against the contaminating action of microorganisms such as bacteria and fungi. The carrier can be a solvent or dispersion medium containing, for example, water, ethanol, polyol (for example, glycerol, propylene glycol, and liquid polyethylene glycol, and the like), and suitable mixtures thereof. The proper fluidity can be maintained, for example, by the use of a coating such as lecithin, by the maintenance ofthe required particle size in the case of dispersion and by the use of surfactants. Prevention of the action of microorganisms can be achieved by various antibacterial and antifungal agents, for example, parabens, chlorobutanol, phenol, ascorbic acid, thimerosal, and the like. In many cases, isotonic agents, for example, sugars, polyalcohols such as mannitol, sorbitol, sodium chloride sometimes are included in the composition. Prolonged absoφtion ofthe injectable compositions can be brought about by including in the composition an agent which delays absoφtion, for example, aluminum monostearate and gelatin. [0183] Sterile injectable solutions can be prepared by incoφorating the active compound in the required amount in an appropriate solvent with one or a combination of ingredients enumerated above, as required, followed by filtered sterilization. Generally, dispersions are prepared by incoφorating the active compound into a sterile vehicle which contains a basic dispersion medium and the required other ingredients from those enumerated above. Lu the case of sterile powders for the preparation of sterile injectable solutions, methods of preparation often utilized are vacuum drying and freeze-drying which yields a powder ofthe active ingredient plus any additional desired ingredient from a previously sterile-filtered solution thereof. [0184] For administration by inhalation, the compounds are delivered in the form of an aerosol spray from pressured container or dispenser which contains a suitable propellant, e.g, a gas such as carbon dioxide, or a nebulizer. [0185] Systemic administration can also be by transmucosal or transdermal means. For transmucosal or transdermal administration, penetrants appropriate to the barrier to be permeated are used in the formulation. Such penetrants are generally known in the art, and include, for example, for transmucosal administration, detergents, bile salts, and fusidic acid derivatives. Transmucosal administration can be accomplished through the use of nasal sprays or suppositories. For transdermal administration, the active compounds are formulated into ointments, salves, gels, or creams as generally known in the art. Molecules can also be prepared in the form of suppositories (e.g, with conventional suppository bases such as cocoa butter and other glycerides) or retention enemas for rectal delivery. [0186] Lu one embodiment, active molecules are prepared with carriers that will protect the compound against rapid elimination from the body, such as a controlled release formulation, including implants and microencapsulated delivery systems. Biodegradable, biocompatible polymers can be used, such as ethylene vinyl acetate, polyanhydrides, polyglycolic acid, collagen, polyorthoesters, and polylactic acid. Methods for preparation of such formulations will be apparent to those skilled in the art. Materials can also be obtained commercially from Alza Coφoration and Nova Pharmaceuticals, Luc. Liposomal suspensions (including liposomes targeted to infected cells with monoclonal antibodies to viral antigens) can also be used as pharmaceutically acceptable carriers. These can be prepared according to methods known to those skilled in the art, for example, as described in U.S. Patent No. 4,522,811. [0187] It is advantageous to formulate oral or parenteral compositions in dosage unit form for ease of administration and uniformity of dosage. Dosage unit form as used herein refers to physically discrete units suited as unitary dosages for the subject to be treated; each unit containing a predetermined quantity of active compound calculated to produce the desired therapeutic effect in association with the required pharmaceutical carrier. [0188] Toxicity and therapeutic efficacy of such compounds can be determined by standard pharmaceutical procedures in cell cultures or experimental animals, e.g, for determining the LD₅₀ (the dose lethal to 50% ofthe population) and the ED₅₀ (the dose therapeutically effective in 50% of the population). The dose ratio between toxic and therapeutic effects is the therapeutic index and it can be expressed as the ratio LD50/ED₅₀. Molecules which exhibit high therapeutic indices often are utilized. While molecules that exhibit toxic side effects may be used, care should be taken to design a delivery system that targets such compounds to the site of affected tissue in order to minimize potential damage to uninfected cells and, thereby, reduce side effects. [0189] The data obtained from the cell culture assays and animal studies can be used in formulating a range of dosage for use in humans. The dosage of such molecules often lies within a range of circulating concentrations that include the ED₅₀ with little or no toxicity. The dosage may vary within this range depending upon the dosage form employed and the route of administration utilized. For any molecules used in the methods described herein, the therapeutically effective dose can be estimated initially from cell culture assays. A dose may be formulated in animal models to achieve a circulating plasma concentration range that includes the IC₅₀ (i.e., the concentration ofthe test compound which achieves a half-maximal inhibition of symptoms) as determined in cell culture. Such information can be used to more accurately determine useful doses in humans. Levels in plasma may be measured, for example, by high performance liquid chromatography. [0190] As defined herein, a therapeutically effective amount of protein or polypeptide (i.e, an effective dosage) ranges from about 0.001 to 30 mg/kg body weight, sometimes about 0.01 to 25 mg/kg body weight, often about 0.1 to 20 mg/kg body weight, and more often about 1 to 10 mg/kg,

2 to 9 mg/kg, 3 to 8 mg/kg, 4 to 7 mg/kg, or 5 to 6 mg/kg body weight. The protein or polypeptide can be administered one time per week for between about 1 to 10 weeks, sometimes between 2 to 8 weeks, often between about 3 to 7 weeks, and more often for about 4, 5, or 6 weeks. The skilled artisan will appreciate that certain factors may influence the dosage and timing required to effectively treat a subject, including but not limited to the severity ofthe disease or disorder, previous treatments, the general health and or age ofthe subject, and other diseases present. Moreover, treatment of a subject with a therapeutically effective amount of a protein, polypeptide, or antibody can include a single treatment, or sometimes can include a series of treatments. [0191] With regard to polypeptide formulations, featured herein is a method for treating breast cancer in a subject, which comprises contacting one or more cells in the subject with a first SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide, where the subject comprises a second SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide having one or more polymoφhic variations associated with cancer, and where the first polypeptide comprises fewer polymorphic variations associated with cancer than the second polypeptide. The first and second polypeptides are encoded by a nucleic acid which comprises a nucleotide sequence selected from the group consisting ofthe nucleotide sequence of SEQ ED NO: 1-12; a nucleotide sequence which encodes a polypeptide consisting of an amino acid sequence encoded by a nucleotide sequence of SEQ ED NO: 1 -12; a nucleotide sequence which encodes a polypeptide that is 90% or more identical to an amino acid sequence encoded by a nucleotide sequence of SEQ ED NO: 1-12 and a nucleotide sequence 90% or more identical to a nucleotide sequence of SEQ ED NO: 1-12. The subject is often a human. [0192] For antibodies, a dosage of 0.1 mg/kg of body weight (generally 10 mg/kg to 20 mg/kg) is often utilized. If the antibody is to act in the brain, a dosage of 50 mg/kg to 100 mg/kg is often appropriate. Generally, partially human antibodies and fully human antibodies have a longer half- life within the human body than other antibodies. Accordingly, lower dosages and less frequent administration is often possible. Modifications such as lipidation can be used to stabilize antibodies and to enhance uptake and tissue penetration (e.g, into the brain). A method for lipidation of antibodies is described by Cruikshank et al, J. Acquired Immune Deficiency Syndromes and Human Retrovirology 14:193 (1997). [0193] Antibody conjugates can be used for modifying a given biological response, the drug moiety is not to be construed as limited to classical chemical therapeutic agents. For example, the drag moiety may be a protein or polypeptide possessing a desired biological activity. Such proteins may include, for example, a toxin such as abrin, ricin A, pseudomonas exotoxin, or diphtheria toxin; a polypeptide such as tumor necrosis factor, .alpha.-interferon, .beta.-interferon, nerve growth factor, platelet derived growth factor, tissue plasminogen activator; or, biological response modifiers such as, for example, lymphokines, interleukin-1 ("EL-1"), mterleukin-2 ("EL-2"), interleukin-6 ("EL-6"), granulocyte macrophage colony stimulating factor ("GM-CSF"), granulocyte colony stimulating factor ("G-CSF"), or other growth factors. Alternatively, an antibody can be conjugated to a second antibody to form an antibody heteroconjugate as described by Segal in U.S. Patent No. 4,676,980. [0194] For compounds, exemplary doses include milligram or microgram amounts ofthe compound per kilogram of subject or sample weight, for example, about 1 microgram per kilogram to about 500 milligrams per kilogram, about 100 micrograms per kilogram to about 5 milHgrams per kilogram, or about 1 microgram per kilogram to about 50 micrograms per kilogram. It is understood that appropriate doses of a small molecule depend upon the potency ofthe small molecule with respect to the expression or activity to be modulated. When one or more of these small molecules is to be administered to an animal (e.g, a human) in order to modulate expression or activity of a polypeptide or nucleic acid described herein, a physician, veterinarian, or researcher may, for example, prescribe a relatively low dose at first, subsequently increasing the dose until an appropriate response is obtained. Lu addition, it is understood that the specific dose level for any particular animal subject will depend upon a variety of factors including the activity ofthe specific compound employed, the age, body weight, general health, gender, and diet ofthe subject, the time of administration, the route of administration, the rate of excretion, any drag combination, and the degree of expression or activity to be modulated. [0195] SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 nucleic acid molecules can be inserted into vectors and used in gene therapy methods for treating breast cancer. Featured herein is a method for treating breast cancer in a subject, which comprises contacting one or more cells in the subject with a first SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 nucleic acid, where genomic DNA in the subject comprises a second SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 nucleic acid comprising one or more polymoφhic variations associated with breast cancer, and where the first SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 nucleic acid comprises fewer polymoφhic variations associated with breast cancer. The first and second nucleic acids typically comprise a nucleotide sequence selected from the group consisting ofthe nucleotide sequence of SEQ ED NO: 1-12; a nucleotide sequence which encodes a polypeptide consisting of an amino acid sequence encoded by a nucleotide sequence of SEQ ED NO: 1 -12; a nucleotide sequence that is 90% or more identical to the nucleotide sequence of SEQ ED NO: 1-12, and a nucleotide sequence which encodes a polypeptide that is 90% or more identical to an amino acid sequence encoded by a nucleotide sequence of SEQ ID NO: 1-12. The subject often is a human. [0196] Gene therapy vectors can be delivered to a subject by, for example, intravenous injection, local administration (see U.S. Patent 5,328,470) or by stereotactic injection (see e.g, Chen et al, (1994) Proc. Natl. Acad. Sci. USA 91:3054-3057). Pharmaceutical preparations of gene therapy vectors can include a gene therapy vector in an acceptable diluent, or can comprise a slow release matrix in which the gene delivery vehicle is imbedded. Alternatively, where the complete gene delivery vector can be produced intact from recombinant cells (e.g, retroviral vectors) the pharmaceutical preparation can include one or more cells which produce the gene delivery system. Examples of gene delivery vectors are described herein. [0197] Pharmaceutical compositions can be included in a container, pack, or dispenser together with instractions for administration. [0198] Pharmaceutical compositions of active ingredients can be administered by any ofthe paths described herein for therapeutic and prophylactic methods for treating breast cancer. With regard to both prophylactic and therapeutic methods of treatment, such treatments may be specifically tailored or modified, based on knowledge obtained from pharmacogenomic analyses described herein. As used herein, the term "treatment" is defined as the application or administration of a therapeutic agent to a patient, or application or administration of a therapeutic agent to an isolated tissue or cell line from a patient, who has a disease, a symptom of disease or a predisposition toward a disease, with the puφose to cure, heal, alleviate, relieve, alter, remedy, ameliorate, improve or affect the disease, the symptoms of disease or the predisposition toward disease. A therapeutic agent includes, but is not limited to, small molecules, peptides, antibodies, ribozymes and antisense oligonucleotides. [0199] Administration of a prophylactic agent can occur prior to the manifestation of symptoms characteristic ofthe SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 aberrance, such that a disease or disorder is prevented or, alternatively, delayed in its progression. Depending on the type of SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 aberrance, for example, a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 molecule, SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 agonist, or SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 antagonist agent can be used for treating the subject. The appropriate agent can be determined based on screening assays described herein. [0200] As discussed, successful treatment of SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 disorders can be brought about by techniques that serve to inhibit the expression or activity of target gene products. For example, compounds (e.g, an agent identified using an assays described above) that exhibit negative modulatory activity can be used to prevent and/or treat breast cancer. Such molecules can include, but are not limited to peptides, phosphopeptides, small organic or inorganic molecules, or antibodies (including, for example, polyclonal, monoclonal, humanized, anti-idiotypic, chimeric or single chain antibodies, and FAb, F(ab')2 and FAb expression library fragments, scFV molecules, and epitope-binding fragments thereof). [0201] Further, antisense and ribozyme molecules that inhibit expression ofthe target gene can also be used to reduce the level of target gene expression, thus effectively reducing the level of target gene activity. Still further, triple helix molecules can be utilized in reducing the level of target gene activity. Antisense, ribozyme and triple helix molecules are discussed above. [0202] It is possible that the use of antisense, ribozyme, and/or triple helix molecules to reduce or inhibit mutant gene expression can also reduce or inhibit the transcription (triple helix) and/or translation (antisense, ribozyme) of mRNA produced by normal target gene alleles, such that the concentration of normal target gene product present can be lower than is necessary for a normal phenotype. n such cases, nucleic acid molecules that encode and express target gene polypeptides exhibiting normal target gene activity can be introduced into cells via gene therapy method. Alternatively, in instances where the target gene encodes an extracellular polypeptide, normal target gene polypeptide often is co-administered into the cell or tissue to maintain the requisite level of cellular or tissue target gene activity. [0203] Another method by which nucleic acid molecules may be utilized in treating or preventing a disease characterized by SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 expression is through the use of aptamer molecules specific for SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide. Aptamers are nucleic acid molecules having a tertiary stracture which permits them to specifically bind to polypeptide ligands (see, e.g, Osborne, et al, Curr. Opin. Chem. Biol.l(l): 5-9 (1997); and Patel, D. J, Curr. Opin. Chem. Biol. Jun;l(l): 32-46 (1997)). Since nucleic acid molecules may in many cases be more conveniently introduced into target cells than therapeutic polypeptide molecules may be, aptamers offer a method by which SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide activity may be specifically decreased without the introduction of drugs or other molecules which may have pluripotent effects. ' [0204] Antibodies can be generated that are, both specific for target gene product and that reduce target gene product activity. Such antibodies may, therefore, by administered in instances whereby negative modulatory techniques are appropriate for the treatment of SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 disorders. For a description of antibodies, see the Antibody section above. [0205] Lu circumstances where injection of an animal or a human subject with a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCH 5209 or HRMT1L3 polypeptide or epitope for stimulating antibody production is harmful to the subject, it is possible to generate an immune response against SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 through the use of anti-idiotypic antibodies (see, for example, Herlyn, D, Ann. Med.;31(l): 66-78 (1999); and Bhattacharya- Chatterjee & Foon, Cancer Treat. Res.; 94: 51-68 (1998)). If an anti-idiotypic antibody is introduced into a mammal or human subject, it should stimulate the production of anti-anti- idiotypic antibodies, which should be specific to the SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide. Vaccines directed to a disease characterized by SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 expression may also be generated in this fashion. [0206] En instances where the target antigen is intracellular and whole antibodies are used, internalizing antibodies may be utilized. Lipofectin or liposomes can be used to deliver the antibody or a fragment ofthe Fab region that binds to the target antigen into cells. Where fragments ofthe antibody are used, the smallest inhibitory fragment that binds to the target antigen often is utilized. For example, peptides having an ammo acid sequence corresponding to the Fv region ofthe antibody can be used. Alternatively, single chain neutralizing antibodies that bind to intracellular target antigens can also be administered. Such single chain antibodies can be administered, for example, by expressing nucleotide sequences encoding single-chain antibodies within the target cell population (see e.g, Marasco et al, Proc. Natl. Acad. Sci. USA 90: 7889-7893 (1993)). [0207] SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 molecules and compounds that inhibit target gene expression, synthesis and/or activity can be administered to a patient at therapeutically effective doses to prevent, treat or ameliorate SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 disorders. A therapeutically effective dose refers to that amount ofthe compound sufficient to result in amelioration of symptoms ofthe disorders. [0208] Toxicity and therapeutic efficacy of such compounds can be determined by standard pharmaceutical procedures in cell cultures or experimental animals, e.g, for determining the LD₅₀ (the dose lethal to 50% ofthe population) and the ED₅₀ (the dose therapeutically effective in 50% of the population). The dose ratio between toxic and therapeutic effects is the therapeutic index and it can be expressed as the ratio LD₅o/ED₅₀. Compounds that exhibit large therapeutic indices often are utilized. While compounds that exhibit toxic side effects can be used, care should be taken to design a delivery system that targets such compounds to the site of affected tissue in order to minimize potential damage to uninfected cells and, thereby, reduce side effects. [0209] Data obtained from cell culture assays and animal studies can be used in formulating a range of dosage for use in humans. The dosage of such compounds often lies within a range of circulating concentrations that include the ED₅₀ with little or no toxicity. The dosage can vary within this range depending upon the dosage form employed and the route of administration utilized. For any compound used in a method described herein, the therapeutically effective dose can be estimated initially from cell culture assays. A dose can be formulated in animal models to achieve a circulating plasma concentration range that includes the IC₅₀ (i.e, the concentration ofthe test compound that achieves a half-maximal inhibition of symptoms) as determined in cell culture. Such information can be used to more accurately determine useful doses in humans. Levels in plasma can be measured, for example, by high performance liquid chromatography. [0210] Another example of effective dose determination for an individual is the ability to directly assay levels of "free" and "bound" compound in the serum ofthe test subject. Such assays may utilize antibody mimics and/or "biosensors" that have been created through molecular imprinting techniques. The compound which is able to modulate SPUVE, GRIN3A, PFTKl,

SERPINA5, LOCI 15209 or HRMT1L3 activity is used as a template, or "imprinting molecule", to spatially organize polymerizable monomers prior to their polymerization with catalytic reagents. The subsequent removal ofthe imprinted molecule leaves a polymer matrix which contains a repeated "negative image" ofthe compound and is able to selectively rebind the molecule under biological assay conditions. A detailed review of this technique can be seen in Ansell et al. Current Opinion in Biotechnology 7: 89-94 (1996) and in Shea, Trends in Polymer Science 2: 166-173 (1994). Such "imprinted" affinity matrixes are amenable to ligand-binding assays, whereby the immobilized monoclonal antibody component is replaced by an appropriately imprinted matrix. An example ofthe use of such matrixes in this way can be seen in Vlatakis, et al. Nature 361 : 645-647 (1993). Through the use of isotope-labeling, the "free" concentration of compound which modulates the expression or activity of SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 can be readily monitored and used in calculations of IC₅₀. Such "imprinted" affinity matrixes can also be designed to include fluorescent groups whose photon-emitting properties measurably change upon local and selective binding of target compound. These changes can be readily assayed in real time using appropriate fiberoptic devices, in turn allowing the dose in a test subject to be quickly optimized based on its individual IC₅o. A rudimentary example of such a "biosensor" is discussed inKriz et al. Analytical Chemistry 67: 2142-2144 (1995). [0211] Provided herein are methods of modulating SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 expression or activity for therapeutic puφoses. Accordingly, in an exemplary embodiment, the modulatory method involves contacting a cell with a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 or agent that modulates one or more ofthe activities of SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide activity associated with the cell. An agent that modulates SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide activity can be an agent as described herein, such as a nucleic acid or a polypeptide, a naturally-occurring target molecule of a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide (e.g, a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 substrate or receptor), a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 antibody, a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 agonist or antagonist, a peptidomimetic of a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCH 5209 or HRMT1L3 agonist or antagonist, or other small molecule. [0212] En one embodiment, the agent stimulates one or more SPUVE, GRIN3A, PFTKl,

SERPINA5, LOCI 15209 or HRMT1L3 activities. Examples of such stimulatory agents include active SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide and a nucleic acid molecule encoding SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3. n another embodiment, the agent inhibits one or more SPUVE, GRIN3A, PFTKl, SERPINA5,

LOCI 15209 or HRMT1L3 activities. Examples of such inhibitory agents include antisense SPUVE,

GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 nucleic acid molecules, ani-SPUVE, 61 GRIN3A, PFTKl, SERPLNA5, LOCI 15209 or HRMT1L3 antibodies, and SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 inhibitors. These modulatory methods can be performed in vitro (e.g, by culturing the cell with the agent) or, alternatively, in vivo (e.g, by acmiinistering the agent to a subject). As such, provided are methods of treating an individual afflicted with a disease or disorder characterized by aberrant or unwanted expression or activity of a SPUVE, GRTN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide or nucleic acid molecule. Lu one embodiment, the method involves adrninistering an agent (e.g, an agent identified by a screening assay described herein), or combination of agents that modulates (e.g, upregulates or downregulates) SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 expression or activity. Lu a preferred embodiment, the method involves administering an agent (e.g, an agent identified by a screening assay described herein), or combination of agents that inhibits SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 expression or activity. En another embodiment, the method involves administering a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 polypeptide or nucleic acid molecule as therapy to compensate for reduced, aberrant, or unwanted SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 expression or activity. [0213] Stimulation of SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 activity is desirable in situations in which SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 is abnormally downregulated and/or in which increased SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 activity is likely to have a beneficial effect. For example, stimulation of SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 activity is desirable in situations in which a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 is downregulated and/or in which increased SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 activity is likely to have a beneficial effect. Likewise, inhibition of SPUVE, GRTN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 activity is desirable in situations in which SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 is abnormally upregulated and/or in which decreased SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 activity is likely to have a beneficial effect.

Methods of Treatment [0214] In another aspect, provided are methods for identifying a risk of cancer in an individual as described herein and, if a genetic predisposition is identified, treating that individual to delay or reduce or prevent the development of cancer. Such a procedure can be used to treat breast cancer.

Optionally, treating an individual for cancer may include inhibiting cellular proliferation, inhibiting metastasis, inhibiting invasion, or preventing tumor formation or growth as defined herein. Suitable treatments to prevent or reduce or delay breast cancer focus on inhibiting additional cellular proliferation, inhibiting metastasis, inhibiting invasion, and preventing further tumor formation or growth. Treatment usually includes surgery followed by radiation therapy. Surgery may be a lumpectomy or a mastectomy (e.g, total, simple or radical). Even if the doctor removes all ofthe cancer that can be seen at the time of surgery, the patient may be given radiation therapy, chemotherapy, or hormone therapy after surgery to try to kill any cancer cells that may be left.

Radiation therapy is the use of x-rays or other types of radiation to kill cancer cells and shrink tumors. Radiation therapy may use external radiation (using a machine outside the body) or internal radiation. Chemotherapy is the use of drugs to kill cancer cells. Chemotherapy may be taken by mouth, or it may be put into the body by inserting a needle into a vein or muscle. Hormone therapy often focuses on estrogen and progesterone, which are hormones that affect the way some cancers grow. If tests show that the cancer cells have estrogen and progesterone receptors (molecules foimd in some cancer cells to which estrogen and progesterone will attach), hormone therapy is used to block the way these hormones help the cancer grow. Hormone therapy with tamoxifen is often given to patients with early stages of breast cancer and those with metastatic breast cancer. Other types of treatment being tested in clinical trials include sentinel lymph node biopsy followed by surgery and high-dose chemotherapy with bone marrow transplantation and peripheral blood stem cell transplantation. Any preventative/therapeutic treatment known in the art may be prescribed and/or administered, including, for example, surgery, chemotherapy and/or radiation treatment, and any ofthe treatments may be used in combination with one another to treat or prevent breast cancer

(e.g, surgery followed by radiation therapy). [0215] Also provided are methods of preventing or treating cancer comprising providing an individual in need of such treatment with a SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or

HRMT1L3 inhibitor that reduces or inhibits the overexpression of mutant SPUVE, GRIN3A,

PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 (e.g, a SPUVE, GRIN3A, PFTKl, SERPINA5,

LOCI 15209 or HRMT1L3 polynucleotide with an allele that is associated with cancer). Included herein are methods of reducing or blocking the expression of SPUVE, GRIN3A, PFTKl,

SERPINA5, LOCI 15209 or HRMT1L3 comprising providing or administering to individuals in need of reducing or blocking the expression of SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or

HRMT1L3 a pharmaceutical or physiologically acceptable composition comprising a molecule capable of inhibiting expression of SPUVE, GRIN3A, PFTKl, SERPINA5, LOC115209 or

HRMT1L3, e.g, a siRNA molecule. Also included herein are methods of reducing or blocking the expression of secondary regulatory genes regulated by SPUVE, GRIN3A, PFTKl, SERPINA5,

LOCI 15209 or HRMT1L3 that play a role in oncogenesis which comprises introducing competitive inhibitors that target SPUVE, GRIN3A, PFTKl, SERPINA5, LOCH 5209 or HRMTlL s effect on these regulatory genes or that block the binding of positive factors necessary for the expression of these regulatory genes. [0216] The examples set forth below are intended to illustrate but not limit the invention.

Examples [0217] En the following studies a group of subjects were selected according to specific parameters relating to breast cancer. Nucleic acid samples obtained from individuals in the study group were subjected to genetic analysis, which identified associations between breast cancer and certain polymoφhic regions in the SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 and HRMT1L3 genes (herein referred to as "target genes", "target nucleotides", "target polypeptides" or simply "targets"). Methods are described for producing SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 and HRMT1L3 polypeptides and polypeptide variants in vitro or in vivo. SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 and HRMT1L3 nucleic acids or polypeptides and variants thereof are utilized for screening test molecules for those that interact with SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 and HRMT1L3 molecules. Test molecules identified as interactors with SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 and HRMT1L3 molecules and variants are further screened in vivo to determine whether they treat breast cancer. Also, methods are described for producing siRNA molecules capable of inhibiting target gene expression, measuring the effect of siRNA molecules on cellular proliferation ofthe target, and screening for target inhibitors.

Example 1 Samples and Pooling Strategies

Sample Selection [0218] Blood samples were collected from individuals diagnosed with breast cancer, which were referred to as case samples. Also, blood samples were collected from individuals not diagnosed with breast cancer as gender and age-matched controls. All ofthe samples were of German/German descent. A database was created that listed all phenotypic trait information gathered from individuals for each case and control sample. Genomic DNA was extracted from each ofthe blood samples for genetic analyses.

DNA Extraction from Blood Samples [0219] Six to ten milliliters of whole blood was transferred to a 50 ml tube containing 27 ml of red cell lysis solution (RCL). The tube was inverted until the contents were mixed. Each tube was incubated for 10 minutes at room temperature and inverted once during the incubation. The tubes were then centrifuged for 20 minutes at 3000 x g and the supernatant was carefully poured off. 100-200 μl of residual liquid was left in the tube and was pipetted repeatedly to resuspend the pellet in the residual supernatant. White cell lysis solution (WCL) was added to the tube and pipetted repeatedly until completely mixed. While no incubation was normally required, the solution was incubated at 37°C or room temperature if cell clumps were visible after mixing until the solution was homogeneous. 2 ml of protein precipitation was added to the cell lysate. The mixtures were vortexed vigorously at high speed for 20 sec to mix the protein precipitation solution uniformly with the cell lysate, and then centrifuged for 10 minutes at 3000 x g. The supernatant containing the DNA was then poured into a clean 15 ml tube, which contained 7 ml of 100% isopropanol. The samples were mixed by inverting the tubes gently until white threads of DNA were visible. Samples were centrifuged for 3 minutes at 2000 x g and the DNA was visible as a small white pellet. The supernatant was decanted and 5 ml of 70% ethanol was added to each tube. Each tube was inverted several times to wash the DNA pellet, and then centrifuged for 1 minute at 2000 x g. The ethanol was decanted and each tube was drained on clean absorbent paper. The DNA was dried in the tube by inversion for 10 minutes, and then 1000 μl of IX TE was added. The size of each sample was estimated, and less TE buffer was added during the following DNA hydration step if the sample was smaller. The DNA was allowed to rehydrate overnight at room temperature, and DNA samples were stored at 2-8°C. [0220] DNA was quantified by placing samples on a hematology mixer for at least 1 hour. DNA was serially diluted (typically 1 : 80, 1 : 160, 1 :320, and 1 :640 dilutions) so that it would be within the measurable range of standards. 125 μl of diluted DNA was transferred to a clear U- botto microtitre plate, and 125 μl of IX TE buffer was transferred into each well using a multichannel pipette. The DNA and IX TE were mixed by repeated pipetting at least 15 times, and then the plates were sealed. 50 μl of diluted DNA was added to wells A5-H12 of a black flat bottom microtitre plate. Standards were inverted six times to mix them, and then 50 μl of IX TE buffer was pipetted into well Al, 1000 ng/ml of standard was pipetted into well A2, 500 ng/ml of standard was pipetted into well A3, and 250 ng/ml of standard was pipetted into well A4. PicoGreen (Molecular Probes, Eugene, Oregon) was thawed and freshly diluted 1 :200 according to the number of plates that were being measured. PicoGreen was vortexed and then 50μl was pipetted into all wells ofthe black plate with the diluted DNA. DNA and PicoGreen were mixed by pipetting repeatedly at least 10 times with the multichannel pipette. The plate was placed into a Fluoroskan Ascent Machine (microplate fluorometer produced by Labsystems) and the samples were allowed to incubate for 3 minutes before the machine was run using filter pairs 485 nm excitation and 538 nm emission wavelengths. Samples having measured DNA concentrations of greater than 450 ng/μl were re-measured for conformation. Samples having measured DNA concentrations of 20 ng/μl or less were re-measured for confirmation. Pooling Strategies [0221] Samples were placed into one of two groups based on disease status. The two groups were female case groups and female control groups. A select set of samples from each group were utilized to generate pools, and one pool was created for each group. Each individual sample in a pool was represented by an equal amount of genomic DNA. For example, where 25 ng of genomic DNA was utilized in each PCR reaction and there were 200 individuals in each pool, each individual would provide 125 pg of genomic DNA. Inclusion or exclusion of samples for a pool was based upon the following criteria: the sample was derived from an individual characterized as Caucasian; the sample was derived from an individual of German paternal and maternal descent; the database included relevant phenotype information for the individual; case samples were derived from individuals diagnosed with breast cancer; control samples were derived from individuals free of cancer and no family history of breast cancer; and sufficient genomic DNA was extracted from each blood sample for all allelotyping and genotyping reactions performed during the study. Phenotype information included pre- or post-menopausal, familial predisposition, country or origin of mother and father, diagnosis with breast cancer (date of primary diagnosis, age of individual as of primary diagnosis, grade or stage of development, occurrence of metastases, e.g, lymph node metastases, organ metastases), condition of body tissue (skin tissue, breast tissue, ovary tissue, peritoneum tissue and myometrium), method of treatment (surgery, chemotherapy, hormone therapy, radiation therapy). Samples that met these criteria were added to appropriate pools based on gender and disease status. [0222] The selection process yielded the pools set forth in Table 1 , which were used in the studies that follow:

Table 1

[0223] A whole-genome screen was performed to identify particular SNPs associated with occurrence of breast cancer. As described in Example 1, two sets of samples were utilized, which included samples from female individuals having breast cancer (breast cancer cases) and samples from female individuals not having cancer (female controls). The initial screen of each pool was performed in an allelotyping study, in which certain samples in each group were pooled. By pooling DNA from each group, an allele frequency for each SNP in each group was calculated. These allele frequencies were then compared to one another. Particular SNPs were considered as being associated with breast cancer when allele frequency differences calculated between case and control pools were statistically significant. SNP disease association results obtained from the allelotyping study were then validated by genotyping each associated SNP across all samples from each pool. The results ofthe genotyping were then analyzed, allele frequencies for each group were calculated from the individual genotyping results, and a p-value was calculated to determine whether the case and control groups had statistically significantly differences in allele frequencies for a particular SNP. When the genotyping results agreed with the original allelotyping results, the SNP disease association was considered validated at the genetic level.

SNP Panel Used for Genetic Analyses [0224] A whole-genome SNP screen began with an initial screen of approximately 25,000 SNPs over each set of disease and control samples using a pooling approach. The pools studied in the screen are described in Example 1. The SNPs analyzed in this study were part of a set of 25,488 SNPs corifirmed as being statistically polymoφhic as each is characterized as having a minor allele frequency of greater than 10%. The SNPs in the set reside in genes or in close proximity to genes, and many reside in gene exons. Specifically, SNPs in the set are located in exons, introns, and within 5,000 base-pairs upstream of a transcription start site of a gene. In addition, SNPs were selected according to the following criteria: they are located in ESTs; they are located in Locuslink or Ensemble genes; and they are located in Genomatix promoter predictions. SNPs in the set also were selected on the basis of even spacing across the genome, as depicted in Table 2. [0225] A case-control study design using a whole genome association strategy involving approximately 28,000 single nucleotide polymoφhisms (SNPs) was employed. Approximately 25,000 SNPs were evenly spaced in gene-based regions ofthe human genome with a median inter- marker distance of about 40,000 base pairs. Additionally, approximately 3,000 SNPs causing amino acid substitutions in genes described in the literature as candidates for various diseases were used. The case-control study samples were of female German origin (German paternal and maternal descent) 548 individuals were equally distributed in two groups (female controls and female cases). The whole genome association approach was first conducted on 2 DNA pools representing the 2 groups. Significant markers were confirmed by individual genotyping. , Table 2

Allelotyping and Genotyping Results [0226] The genetic studies summarized above and described in more detail below identified allelic variants associated with breast cancer. The allelic variants identified from the SNP panel describqd in Table 2 are summarized below in Table 3.

Table 3

[0227] Table 3 includes information pertaining to the incident polymoφhic variant associated with breast cancer identified herein. Each variant is in a separate locus, where rsl939110, rsl407877, rs2040521, rs6119, rs3087585 and rs876594 are in SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 and HRMT1L3, respectively. Public information pertaining to the polymoφhism and the genomic sequence that includes the polymoφhism are indicated. The genomic sequences identified in Table 3 may be accessed at the http address www.ncbi.nih.gov/entrez/query.fcgi, for example, by using the publicly available SNP reference number (e.g., rsl 939110). The chromosome position refers to the position ofthe SNP within NCBI's Genome Build 34, which may be accessed at the following http address: www.ncbi.nlm.nih.gov/mapview/map_search.cgi?chr=hum_chr.inf&query=. The "Contig Position" provided in Table 3 corresponds to a nucleotide position set forth in the contig sequence, and designates the polymoφhic site corresponding to the SNP reference number. The sequence containing the polymoφhisms also may be referenced by the "Sequence Identification" set forth in Table 3. The "Sequence Identification" corresponds to cDNA sequence that encodes associated target polypeptides (e.g., SPUVE) ofthe invention. The position ofthe SNP within the cDNA sequence is provided in the "Sequence Position" column of Table 3. Also, the allelic variation at the polymoφhic site and the allelic variant identified as associated with breast cancer is specified in Table 3. All nucleotide sequences referenced and accessed by the parameters set forth in Table 3 are incoφorated herein by reference.

Assay for Verifying. Allelotyping. and Genotyping SNPs [0228] A MassARRAY™ system (Sequenom, Inc.) was utilized to perform SNP genotyping in a high-throughput fashion. This genotyping platform was complemented by a homogeneous, single-tube assay method (hME™ or homogeneous MassEXTEND™ (Sequenom, Inc.)) in which two genotyping primers anneal to and amplify a genomic target surrounding a polymoφhic site of interest. A third primer (the MassEXTEND™ primer), which is complementary to the amplified target up to but not including the polymoφhism, was then enzymatically extended one or a few bases through the polymoφhic site and then tenninated. [0229] For each polymoφhism, SpectroDESIGNER™ software (Sequenom, Inc.) was used to generate a set of PCR primers and a MassEXTEND™ primer was used to genotype the polymoφhism. Table 4 shows PCR primers and Table 5 shows extension primers used for analyzing polymoφhisms. The initial PCR amplification reaction was performed in a 5 μl total volume containing IX PCR buffer with 1.5 mM MgCl₂ (Qiagen), 200 μM each of dATP, dGTP, dCTP, dTTP (Gibco-BRL), 2.5 ng of genomic DNA, 0.1 units of HotStar DNA polymerase (Qiagen), and 200 nM each of forward and reverse PCR primers specific for the polymoφhic region of interest.

Table 4: PCR Primers

[0230] Samples were incubated at 95°C for 15 minutes, followed by 45 cycles of 95°C for 20 seconds, 56°C for 30 seconds, and 72°C for 1 minute, finishing with a 3 minute final extension at 72°C. Following amplification, shrimp alkaline phosphatase (SAP) (0.3 units in a 2 μl volume) (Amersham Pharmacia) was added to each reaction (total reaction volume was 7 μl) to remove any residual dNTPs that were not consumed in the PCR step. Samples were incubated for 20 minutes at 37°C, followed by 5 minutes at 85°C to denature the SAP. [0231] Once the SAP reaction was complete, a primer extension reaction was initiated by adding a polymoφhism-specific MassEXTEND™ primer cocktail to each sample. Each MassEXTEND™ cocktail included a specific combination of dideoxynucleotides (ddNTPs) and deoxynucleotides (dNTPs) used to distinguish polymoφhic alleles from one another. In Table 5, ddNTPs are shown and the fourth nucleotide not shown is the dNTP.

Table 5

[0232] The MassEXTEND™ reaction was performed in a total volume of 9 μl, with the addition of IX ThermoSequenase buffer, 0.576 units of ThermoSequenase (Amersham Pharmacia), 600 nM MassEXTEND™ primer, 2 mM of ddATP and/or ddCTP and/or ddGTP and/or ddTTP, and 2 mM of dATP or dCTP or dGTP or dTTP. The deoxy nucleotide (dNTP) used in the assay normally was complementary to the nucleotide at the polymoφhic site in the amplicon. Samples were incubated at 94°C for 2 minutes, followed by 55 cycles of 5 seconds at 94°C, 5 seconds at 52°C, and 5 seconds at 72°C. [0233] Following incubation, samples were desalted by adding 16 μl of water (total reaction volume was 25 μl), 3 mg of SpectroCLEAN™ sample cleaning beads (Sequenom, Luc.) and allowed to incubate for 3 minutes with rotation. Samples were then robotically dispensed using a piezoelectric dispensing device (SpectroJET™ (Sequenom, Luc.)) onto either 96-spot or 384-spot silicon chips containing a matrix that crystallized each sample (SpectroCHEP^® (Sequenom, Luc.)). Subsequently, MALDI-TOF mass spectrometry (Biflex and Autoflex MALDI-TOF mass spectrometers (Bruker Daltonics) can be used) and SpectroTYPER RT™ software (Sequenom, Luc.) were used to analyze and inteφret the SNP genotype for each sample.

Genetic Analysis [0234] Variations identified in the target genes are provided in their respective genomic sequences (see SEQ ED NO: 1-6). Minor allelic frequencies for these polymoφhisms was verified as being 10% or greater by determining the allelic frequencies using the extension assay described above in a group of samples isolated from 92 individuals originating from the state of Utah in the United States, Venezuela and France (Coriell cell repositories). [0235] Genotyping results are shown for female pools in Table 6A and 6B. Table 6A shows the orginal genotyping results and Table 6B shows the genotyped results re-analyzed to remove duplicate individuals from the cases and controls (i.e., individuals who were erroneously included more than once as either cases or controls). Therefore, Table 6B represents a more accurate measure ofthe allele frequencies for this particular SNP. Lu the subsequent tables, "AF" refers to allelic frequency; and "F case" and "F control" refer to female case and female control groups, respectively. Also, rs6119 is a non-synonomous SNP position that encodes a glutamate or lysince at position 105 in SEQ ED NO. 16. The disease associated allele is an adenine, which codes for a lysine; therefore, a lysine at position 105 of SERPLNA5 is associated with an increased risk of breast cancer.

Table 6A

Table 6B

[0236] The single marker alleles set forth in Table 3 were considered validated, since the genotyping data for the females, males or both pools were significantly associated with breast cancer, and because the genotyping results agreed with the original allelotyping results. Particularly significant associations with breast cancer are indicated by a calculated p-value of less than 0.05 for genotype results, which are set forth in bold text. [0237] Odds ratio results are shown in Tables 6A and 6B. An odds ratio is an unbiased estimate of relative risk which can be obtained from most case-control studies. Relative risk (RR.) is an estimate ofthe likelihood of disease in the exposed group (susceptibility allele or genotype carriers) compared to the unexposed group (not carriers). It can be calculated by the following equation: RR = IA/Ia IA is the incidence of disease in the A carriers and la is the incidence of disease in the non- carriers. RR > 1 indicates the A allele increases disease susceptibility. RR < 1 indicates the a allele increases disease susceptibility. For example, RR = 1.5 indicates that carriers ofthe A allele have 1.5 times the risk of disease than non-carriers, i.e., 50% more likely to get the disease. [0238] Case-control studies do not allow the direct estimation of I A and la, therefore relative risk cannot be directly estimated. However, the odds ratio (OR) can be calculated using the following equation: OR = (nDAnda)/(ndAnDa) = >DA(l - pdA)/pdA(l - pDA), or OR = ((case f) / (1- case f)) / ((control f) / (1 -control f)), where f = susceptibility allele frequency. [0239] An odds ratio can be inteφreted in the same way a relative risk is inteφreted and can be directly estimated using the data from case-control studies, i.e., case and control allele frequencies. The higher the odds ratio value, the larger the effect that particular allele has on the development of breast cancer. Possessing an allele associated with a relatively high odds ratio translates to having a higher risk of developing or having breast cancer. Example 3 SPUVE Proximal SNPs [0240] It has been discovered that a polymoφhic variation (rsl 939110) in a gene encoding a serine protease, umbiHcal endothelium (SPUVE) is associated with the occurrence of breast cancer (see Examples 1 and 2). Subsequently, SNPs proximal to the incident SNP (rsl 939110) were identified and allelotyped in breast cancer sample sets and control sample sets as described in Examples 1 and 2. A total of forty-eight allelic variants located within or nearby the SPUVE gene were identified and forty-eight allelic variants were allelotyped. The polymoφhic variants are set forth in Table 7. The chromosome position provided in column four of Table 7 is based on Genome "Build 34" of NCBI's GenBank.

Table 7

Assay for Verifying and Allelotyping SNPs [0241] The methods used to verify and allelotype the thirty-seven proximal SNPs of Table 7 are the same methods described in Examples 1 and 2 herein. The PCR primers and extend primers used in these assays are provided in Table 8 and Table 9, respectively.

Table 8

Table 9

Genetic Analysis of Allelotyping Results [0242] Allelotyping results are shown for cases and controls in Table 10. The allele frequency for the A2 allele is noted in the fifth and sixth columns for breast cancer pools and control pools, respectively, where "AF" is allele frequency. SNPs with blank allele frequencies were untyped. Table 10

[0243] Figure 1 A shows proximal SNPs in and around the SPUVE gene for females. The position of each SNP on the chromosome is presented on the x-axis. The y-axis gives the negative logarithm (base 10) ofthe p-value comparing the estimated allele in the case group to that ofthe control group. The minor allele frequency ofthe control group for each SNP designated by an X or other symbol on the graphs in Figure 1 A can be determined by consulting Table 10. By proceeding down the Table from top to bottom and across the graphs from left to right the allele frequency associated with each symbol shown can be determined. [0244] To aid the inteφretation, multiple lines have been added to the graph. The broken horizontal lines are drawn at two common significance levels, 0.05 and 0.01. The vertical broken lines are drawn every 20kb to assist in the inteφretation of distances between SNPs. Two other lines are drawn to expose linear trends in the association of SNPs to the disease. The light gray line (or generally bottom-most curve) is a nonlinear smoother through the data points on the graph using a local polynomial regression method (W.S. Cleveland, E. Grosse and W.M. Shyu (1992) Local regression models. Chapter 8 of Statistical Models in S eds J.M. Chambers and TJ. Hastie, Wadsworth & Brooks/Cole.). The black line (or generally top-most curve) provides a local test for excess statistical significance to identify regions of association. This was created by use of a lOkb sliding window with lkb step sizes. Within each window, a chi-square goodness of fit test was applied to compare the proportion of SNPs that were significant at a test wise level of 0.01 , to the proportion that would be expected by chance alone (0.05 for the methods used here). Resulting p- values that were less than 10^"8 were truncated at that value. [0245] The gene or genes present in the loci region ofthe proximal SNPs as annotated by Locus Link (http address: www.ncbi.nlm.nih.gov/LocusLink/) are provided on the graph. The exons and introns ofthe genes in the covered region are plotted below each graph at the appropriate chromosomal positions. The gene boundary is indicated by the broken horizontal line. The exon positions are shown as thick, unbroken bars. An arrow is place at the 3' end of each gene to show the direction of transcription.

Example 4 GRIN3A Proximal SNPs [0246] It has been discovered that a polymoφhic variation (rsl407877) in a gene encoding glutamate receptor, ionotropic, N-methyl-D-aspartate 3 A (GRIN3A) is associated with the occurrence of breast cancer (see Examples 1 and 2). Subsequently, SNPs proximal to the incident SNP (rsl407877) were identified and allelotyped in breast cancer sample sets and control sample sets as described in Examples 1 and 2. A total of twenty-one allelic variants located within or nearby the GRIN3A gene were identified and twenty-three allelic variants were allelotyped. The polymoφhic variants are set forth in Table 11. The chromosome position provided in column four of Table 11 is based on Genome "Build 34" of NCBI's GenBank.

Table 11

Assay for Verifying and Allelotyping SNPs [0247] The methods used to verify and allelotype the twenty-one proximal SNPs of Table 11 are the same methods described in Examples 1 and 2 herein. The PCR primers and extend primers used in these assays are provided in Table 12 and Table 13, respectively.

Table 12

Table 13

Genetic Analysis of Allelotyping Results [0248] Allelotyping results are shown for cases and controls in Table 14. The allele frequency for the A2 allele is noted in the fifth and sixth columns for breast cancer pools and control pools, respectively, where "AF" is allele frequency. SNPs with blank allele frequencies were untyped.

Table 14

[0249] Figure IB shows proximal SNPs in and around the GRIN3A gene for females. The position of each SNP on the chromosome is presented on the x-axis. The y-axis gives the negative logarithm (base 10) ofthe p-value comparing the estimated allele in the case group to that ofthe control group. The minor allele frequency ofthe control group for each SNP designated by an X or other symbol on the graphs in Figure IB can be determined by consulting Table 14. By proceeding down the Table from top to bottom and across the graphs from left to right the allele frequency associated with each symbol shown can be determined. [0250] To aid the inteφretation, multiple lines have been added to the graph. The broken horizontal lines are drawn at two common significance levels, 0.05 and 0.01. The vertical broken lines are drawn every 20kb to assist in the inteφretation of distances between SNPs. Two other lines are drawn to expose linear trends in the association of SNPs to the disease. The light gray line (or generally bottom-most curve) is a nonlinear smoother through the data points on the graph using a local polynomial regression method (W.S. Cleveland, E. Grosse and W.M. Shyu (1992) Local regression models. Chapter 8 of Statistical Models in S eds J.M. Chambers and T J. Hastie, Wadsworth & Brooks/Cole.). The black line (or generally top-most curve) provides a local test for excess statistical significance to identify regions of association. This was created by use of a lOkb sliding window with lkb step sizes. Within each window, a chi-square goodness of fit test was applied to compare the proportion of SNPs that were significant at a test wise level of 0.01 , to the proportion that would be expected by chance alone (0.05 for the methods used here). Resulting p- values that were less than 10^"8 were truncated at that value. [0251] The gene or genes present in the loci region ofthe proximal SNPs as annotated by Locus Link (http address: www.ncbi.nlm.nih.gov/LocusLink/) are provided on the graph. The exons and introns ofthe genes in the covered region are plotted below each graph at the appropriate chromosomal positions. The gene boundary is indicated by the broken horizontal line. The exon positions are shown as thick, unbroken bars. An arrow is place at the 3' end of each gene to show the direction of transcription.

Example 5 PFTKl Proximal SNPs [0252] It has been discovered that a polymoφhic variation (rs2040521) in a gene encoding

PFTAIRE protein kinase 1 (PFTKl) is associated with the occurrence of breast cancer (see Examples 1 and 2). Subsequently, SNPs proximal to the incident SNP (rs2040521) were identified and allelotyped in breast cancer sample sets and control sample sets as described in Examples 1 and 2. A total of fifty-three allelic variants located within or nearby the PFTKl gene were identified and fifty-three allelic variants were allelotyped. The polymoφhic variants are set forth in Table 15. The chromosome position provided in column four of Table 15 is based on Genome "Build 34" of NCBI's GenBank. The "gene position" provided in column five of Table 15 refers to the position (e.g., intronic or exonic) of each SNP within or relative to the PFTKl gene.

Table 15

Assay for Verifying and Allelotyping SNPs [0253] The methods used to verify and allelotype the fifty-three proximal SNPs of Table 15 are the same methods described in Examples 1 and 2 herein. The PCR primers and extend primers used in these assays are provided in Table 16 and Table 17, respectively.

Table 16

Table 17

Genetic Analysis of Allelotyping Results [0254] Allelotyping results are shown for cases and controls in Table 18. The allele frequency for the A2 allele is noted in the fifth and sixth columns for breast cancer pools and control pools, respectively, where "AF" is allele frequency. SNPs with blank allele frequencies were untyped.

Table 18

[0255] Figure IC shows proximal SNPs in and around the PFTKl gene for females. The position of each SNP on the chromosome is presented on the x-axis. The y-axis gives the negative logarithm (base 10) ofthe p-value comparing the estimated allele in the case group to that ofthe control group. The minor allele frequency ofthe control group for each SNP designated by an X or other symbol on the graphs in Figure 1 C can be determined by consulting Table 18. By proceeding down the Table from top to bottom and across the graphs from left to right the allele frequency associated with each symbol shown can be determined. [0256] To aid the inteφretation, multiple lines have been added to the graph. The broken horizontal lines are drawn at two common significance levels, 0.05 and 0.01. The vertical broken lines are drawn every 20kb to assist in the inteφretation of distances between SNPs. Two other lines are drawn to expose linear trends in the association of SNPs to the disease. The light gray line (or generally bottom-most curve) is a nonlinear smoother through the data points on the graph using a local polynomial regression method (W.S. Cleveland, E. Grosse and W.M. Shyu (1992) Local regression models. Chapter 8 of Statistical Models in S eds J.M. Chambers and T. J. Hastie, Wadsworth & Brooks/Cole.). The black line (or generally top-most curve) provides a local test for excess statistical significance to identify regions of association. This was created by use of a lOkb sliding window with lkb step sizes. Within each window, a chi-square goodness of fit test was applied to compare the proportion of SNPs that were significant at a test wise level of 0.01, to the proportion that would be expected by chance alone (0.05 for the methods used here). Resulting p- values that were less than 10^"8 were truncated at that value. [0257] The gene or genes present in the loci region ofthe proximal SNPs as annotated by Locus Link (http address: www.ncbi.nlm.nih.gov/LocusLink/) are provided on the graph. The exons and introns ofthe genes in the covered region are plotted below each graph at the appropriate chromosomal positions. The gene boundary is indicated by the broken horizontal line. The exon positions are shown as thick, unbroken bars. An arrow is place at the 3' end of each gene to show the direction of transcription.

Example 6 SERPINA5 Proximal SNPs [0258] It has been discovered that a polymoφhic variation (rs6119) in a gene encoding serine (or cysteine) proteinase inhibitor clade A (alpha-1 antiproteinase, antitrypsin) member 5 (SERPINA5), is associated with the occurrence of breast cancer (see Examples 1 and 2). Subsequently, SNPs proximal to the incident SNP (rs6119) were identified and allelotyped in breast cancer sample sets and control sample sets as described in Examples 1 and 2. A total of 171 allelic variants located within or nearby the SERPINA5 gene were identified and 171 allelic variants were allelotyped. The polymoφhic variants are set forth in Table 19. The chromosome position provided in column four of Table 19 is based on Genome "Build 34" of NCBI's GenBank.

Table 19

Assay for Verifying and Allelotyping SNPs [0259] The methods used to verify and allelotype the 171 proximal SNPs of Table 19 are the same methods described in Examples 1 and 2 herein. The PCR primers and extend primers used in these assays are provided in Table 20 and Table 21, respectively. Table 20

Table 21

Genetic Analysis of Allelotyping Results [0260] Allelotyping results are shown for cases and controls in Table 22. The allele frequency for the A2 allele is noted in the fifth and sixth columns for breast cancer pools and control pools, respectively, where "AF" is allele frequency. SNPs with blank allele frequencies were untyped.

Table 22

[0261] Figure ID shows proximal SNPs in and around the SERPINA5 gene for females. The position of each SNP on the chromosome is presented on the x-axis. The y-axis gives the negative logarithm (base 10) ofthe p-value comparing the estimated allele in the case group to that ofthe control group. The minor allele frequency ofthe control group for each SNP designated by an X or other symbol on the graphs in Figure ID can be determined by consulting Table 22. By proceeding down the Table from top to bottom and across the graphs from left to right the allele frequency associated with each symbol shown can be determined. [0262] To aid the interpretation, multiple lines have been added to the graph. The broken horizontal lines are drawn at two common significance levels, 0.05 and 0.01. The vertical broken lines are drawn every 20kb to assist in the inteφretation of distances between SNPs. Two other lines are drawn to expose linear trends in the association of SNPs to the disease. The light gray line (or generally bottom-most curve) is a nonlinear smoother through the data points on the graph using a local polynomial regression method (W.S. Cleveland, E. Grosse and W.M. Shyu (1992) Local regression models. Chapter 8 of Statistical Models in S eds J.M. Chambers and TJ. Hastie, Wadsworth & Brooks/Cole.). The black line (or generally top-most curve) provides a local test for excess statistical significance to identify regions of association. This was created by use of a lOkb sliding window with lkb step sizes. Within each window, a chi-square goodness of fit test was applied to compare the proportion of SNPs that were significant at a test wise level of 0.01 , to the proportion that would be expected by chance alone (0.05 for the methods used here). Resulting p- values that were less than 10^"8 were truncated at that value. [0263] The gene or genes present in the loci region ofthe proximal SNPs as annotated by Locus Link (http address: www.ncbi.nh3a.nm.gov/L0cusLink/) are provided on the graph. The exons and introns ofthe genes in the covered region are plotted below each graph at the appropriate chromosomal positions. The gene boundary is indicated by the broken horizontal line. The exon positions are shown as thick, unbroken bars. An arrow is place at the 3¹ end of each gene to show the direction of transcription.

Example 7 LOCI 15209 Proximal SNPs [0264] It has been discovered that a polymoφhic variation (rs3087585) in a gene encoding LOCI 15209 (alternatively called MRP-1 throughout the application) is associated with the occurrence of breast cancer (see Examples 1 and 2). Subsequently, SNPs proximal to the incident SNP (rs3087585) were identified and allelotyped in breast cancer sample sets and control sample sets as described in Examples 1 and 2. A total of 100 allelic variants located within or nearby the LOCI 15209 gene were identified and allelotyped. The polymoφhic variants are set forth in Table 23.

Table 23

Assay for Verifying and Allelotyping SNPs [0265] The methods used to verify and allelotype the seventy-eight proximal SNPs of Table 23 are the same methods described in Examples 1 and 2 herein. The PCR primers and extend primers used in these assays are provided in Table 24 and Table 25, respectively. Table 24

Table 25

Genetic Analysis of Allelotyping Results [0266] Allelotyping results are shown for cases and controls in Table 26. The allele frequency for the A2 allele is noted in the fifth and sixth columns for breast cancer pools and control pools, respectively, where "AF" is allele frequency. SNPs with blank allele frequencies were untyped.

Table 26

[0267] Figure IE shows proximal SNPs in and around the LOCI 15209 gene for females. The position of each SNP on the chromosome is presented on the x-axis. The y-axis gives the negative logarithm (base 10) ofthe p-value comparing the estimated allele in the case group to that ofthe control group. The minor allele frequency ofthe control group for each SNP designated by an X or other symbol on the graphs in Figure IE can be determined by consulting Table 26. By proceeding down the Table from top to bottom and across the graphs from left to right the allele frequency associated with each symbol shown can be determined. [0268] To aid the inteφretation, multiple lines have been added to the graph. The broken horizontal lines are drawn at two common significance levels, 0.05 and 0.01. The vertical broken lines are drawn every 20kb to assist in the inteφretation of distances between SNPs. Two other lines are drawn to expose linear trends in the association of SNPs to the disease. The light gray line (or generally bottom-most curve) is a nonlinear smoother through the data points on the graph using a local polynomial regression method (W.S. Cleveland, E. Grosse and W.M. Shyu (1992) Local regression models. Chapter 8 of Statistical Models in S eds J.M. Chambers and T. J. Hastie, Wadsworth & Brooks/Cole.). The black line (or generally top-most curve) provides a local test for excess statistical significance to identify regions of association. This was created by use of a lOkb sliding window with lkb step sizes. Within each window, a chi-square goodness of fit test was applied to compare the proportion of SNPs that were significant at a test wise level of 0.01, to the proportion that would be expected by chance alone (0.05 for the methods used here). Resulting p- values that were less than 10^"8 were truncated at that value. [0269] The gene or genes present in the loci region ofthe proximal SNPs as annotated by Locus Link (http address: www.ncbi.nlm.nm.gov/LocusLink/) are provided on the graph. The exons and introns ofthe genes in the covered region are plotted below each graph at the appropriate chromosomal positions. The gene boundary is indicated by the broken horizontal line. The exon positions are shown as thick, unbroken bars. An arrow is place at the 3' end of each gene to show the direction of transcription.

Additional Genotyping [0270] An additional LOCI 15209 SNP (MRP-l-AD) was genotyped in the discovery cohort. The discovery cohort is described in Example 1. The T allele of SNP MRP-l-AD was found to be associated with breast cancer with a p-value of 0.146. [0271] The methods used to verify and genotype the three proximal SNPs of Table 26 are the same methods described in Examples 1 and 2 herein. The PCR primers and extend primers used in these assays are forward: ACGTTGGATGATGGCTCTTCCCTAACTAAA; reverse: ACGTTGGATGACCAGAGTATATATACCACG; and extend: AAAAATTCAAGCTTCTAAAGTAAA with a terminal mix of ACG.

Example 8 HRMT1L3 Proximal SNPs [0272] It has been discovered that a polymoφhic variation (rs876594) in a gene encoding HMT1 hnRNP methyltransferase-like 3 (S. cerevisiae) (HRMT1L3) is associated with the occurrence of breast cancer (see Examples 1 and 2). Subsequently, SNPs proximal to the incident SNP (rs876594) were identified and allelotyped in breast cancer sample sets and control sample sets as described in Examples 1 and 2. A total of forty-nine allelic variants located within or nearby the HRMT1L3 gene were identified and allelotyped. The polymoφhic variants are set forth in Table 27. The chromosome position provided in column four of Table 27 is based on Genome "Build 34" of NCBI's GenBank.

Table 27

Assay for Verifying and Allelotyping SNPs [0273] The methods used to verify and allelotype the forty-nine proximal SNPs of Table 27 are the same methods described in Examples 1 and 2 herein. The PCR primers and extend primers used in these assays are provided in Table 28 and Table 29, respectively.

Table 28

Table 29

Genetic Analysis of Allelotyping Results [0274] Allelotyping results are shown for cases and controls in Table 30. The allele frequency for the A2 allele is noted in the fifth and sixth columns for breast cancer pools and control pools, respectively, where "AF" is allele frequency. SNPs with blank allele frequencies were untyped.

Table 30

[0275] Figure IF shows proximal SNPs in and around the SPUVE gene for females. The position of each SNP on the chromosome is presented on the x-axis. The y-axis gives the negative logarithm (base 10) ofthe p-value comparing the estimated allele in the case group to that ofthe control group. The minor allele frequency ofthe control group for each SNP designated by an X or other symbol on the graphs in Figure IF can be determined by consulting Table 30. By proceeding down the Table from top to bottom and across the graphs from left to right the allele frequency associated with each symbol shown can be determined. [0276] To aid the inteφretation, multiple lines have been added to the graph. The broken horizontal lines are drawn at two common significance levels, 0.05 and 0.01. The vertical broken lines are drawn every 20kb to assist in the inteφretation of distances between SNPs. Two other lines are drawn to expose linear trends in the association of SNPs to the disease. The tight gray line (or generally bottom-most curve) is a nonlinear smoother through the data points on the graph using a local polynomial regression method (W.S. Cleveland, E. Grosse and W.M. Shyu (1992) Local regression models. Chapter 8 of Statistical Models in S eds J.M. Chambers and TJ. Hastie, Wadsworth & Brooks/Cole.). The black line (or generally top-most curve) provides a local test for excess statistical significance to identify regions of association. This was created by use of a lOkb sliding window with lkb step sizes. Within each window, a chi-square goodness of fit test was applied to compare the proportion of SNPs that were significant at a test wise level of 0.01, to the proportion that would be expected by chance alone (0.05 for the methods used here). Resulting p- values that were less than 10^"8 were truncated at that value. [0277] The gene or genes present in the loci region ofthe proximal SNPs as annotated by Locus Link (http address: www.ncbi.nlm.nih.gov/LocusLink/) are provided on the graph. The exons and introns ofthe genes in the covered region are plotted below each graph at the appropriate chromosomal positions. The gene boundary is indicated by the broken horizontal line. The exon positions are shown as thick, unbroken bars. An arrow is place at the 3' end of each gene to show the direction of transcription.

Additional Genotyping [0278] A total of five HRMT1L3 SNPs, including the incident SNP, were genotyped in the discovery cohort. The discovery cohort is described in Example 1. [0279] The methods used to verify and genotype the four proximal SNPs of Table 33 are the same methods described in Examples 1 and 2 herein. The PCR primers and extend primers used in these assays are provided in Table 31 and Table 32, respectively.

Table 31

Table 32

917564 CGTTTGTCTGCATCCTC AC

[0280] Table 33, below, shows the case and control allele frequencies along with the p-values for all ofthe SNPs genotyped. The chromosome positions provided correspond to NCBI's Build 34.

Table 33: Genotpying Results

Example 9 Inhibition of Target Gene Expression by Transfection of Specific siRNAs [0281] RNAi-based gene inhibition was selected as a rapid way to inhibit expression of SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 and HRMT1L3 in cultured cells. siRNA reagents were selectively designed to target SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 genes. Algorithms useful for designing siRNA molecules specific for SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 and HRMT1L3 are disclosed at the http address www.dharmacon.com. siRNA molecules up to 21 nucleotides in length were utilized. [0282] Table 31 summarizes features ofthe duplexes that were used in the assays to target SPUVE. A non-homologous siRNA reagent (siGL2 control) was used as a negative control, and a non-homologous siRNA reagent (siRNA_RAD21_l 175 control) shown to inhibit the expression of RAD21 and subsequently inhibit cell proliferation was used as a positive control in all ofthe assays described herein.

Table 31

[0283] Table 32 summarizes features ofthe duplexes that were used in the assays to target GRIN3A.

Table 32

[0284] Table 33 summarizes features o the duplexes that were used in the assays to target ' PFTKl.

Table 33

[0285] Table 34 summarizes features ofthe duplexes that were used in the assays to target SERPINA5.

Table 34

[0286] Table 35 summarizes features ofthe duplexes that were used in the assays to target LOC115209.

Table 35

[0287] Table 36 summarizes features ofthe duplexes that were used in the assays to target HRMT1L3.

Table 36

[0288] The siRNAs were transfected in cell lines MCF-7 and T-47D using Lipofectamine™ 2000 reagent from Invitrogen, Coφ. 2,5 μg or 5.0 μg of siRNA was mixed with 6.25 μl or 12.5 μl lipofectamine, respectively, and the mixture was added to cells grown in 6-well plates. Their inhibitory effects on SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 or HRMT1L3 gene expression were confirmed by precision expression analysis by MassARRAY (quantitativeRT-PCR hME), which was performed on RNA prepared from the transfected cells. See Chunming D. and Cantor C. PNAS 100(6):3059-3064 (2003). Cell viability was measured at 1, 2, 4 and 6 days post- transfection. Absorbance values were normalized relative to Day 1. RNA was extracted with Trizole reagent as recommended by the manufacturer (Invitrogen, Coφ.) followed by cDNA synthesis using Superscript™ reverse transcriptase. [0289] The cocktail of siRNA molecules described in Table 31 (SPr rø-directed siRNA) inhibited proliferation of T47D breast cancer cells. The cocktail of siRNA molecules described in Table 31 (■SPt/ E-directed siRNA) also inhibited proliferation of another breast cancer cell line (MCF-7). The cocktail of siRNA molecules described in Table 32 (GRZV3^-directed siRNA) inhibited proliferation of MCF-7 cells. Inhibition of T47D breast cancer cell proliferation by a cocktail of siRNA molecules described in Table 33 (PFTKl -directed siRNA) was observed. Cocktails of siRNA molecules described in Table 33 (PFTKl -directed siRNA), Table 34 (SERPZN4J-directed siRNA), Table 35 (LOCI 15209 - directed siRNA) and Table 36 (Hi? 77i3-directed siRNA) also inhibited proliferation of MCF-7 cancer cells. [0290] These effects were consistent in all six experiments performed, where each data point was an average of 3 wells of a 96-well plate normalized to values obtained from day 1 post transfection. The specificity ofthe active siRNAs, was confirmed with a negative, non- homologous control siRNA (siGL2), and a positive control, siRNA_RAD21_l 175, that targets a known cancer-associated gene, RAD21. [0291] Long term inhibition of gene expression is desirable in certain cases. Therefore, included herein are siRNA duplexes (e.g., those described in Tables 31-36) that are less susceptible to degradation. An example of a modification that decrease susceptibility to degradation is in siSTABLE RNA described at http address www.dharmacon.com.

Example 10 In Vitro Production of Target Polypeptides [0292] cDNA is cloned into a prVEX 2.3-MCS vector (Roche Biochem) using a directional cloning method. A cDNA insert is prepared using PCR with forward and reverse primers having 5' restriction site tags (in frame) and 5-6 additional nucleotides in addition to 3' gene-specific portions, the latter of which is typically about twenty to about twenty-five base pairs in length. A Sal I restriction site is introduced by the forward primer and a Sma I restriction site is introduced by the reverse primer. The ends of PCR products are cut with the corresponding restriction enzymes (i.e., Sal I and Sma I) and the products are gel-purified. The pIVEX 2.3-MCS vector is linearized using the same restriction enzymes, and the fragment with the correct sized fragment is isolated by gel-purification. Purified PCR product is ligated into the linearized pTVEX 2.3-MCS vector and E. coli cells transformed for plasmid amplification. The newly constructed expression vector is verified by restriction mapping and used for protein production. [0293] E. coli lysate is reconstituted with 0.25 ml of Reconstitution Buffer, the Reaction Mix is reconstituted with 0.8 ml of Reconstitution Buffer; the Feeding Mix is reconstituted with 10.5 ml of Reconstitution Buffer; and the Energy Mix is reconstituted with 0.6 ml of Reconstitution Buffer. 0.5 ml ofthe Energy Mix was added to the Feeding Mix to obtain the Feeding Solution. 0.75 ml of Reaction Mix, 50 μl of Energy Mix, and 10 μg ofthe template DNA is added to the E. coli lysate. [0294] Using the reaction device (Roche Biochem), 1 ml of the Reaction Solution is loaded into the reaction compartment. The reaction device is turned upside-down and 10 ml ofthe Feeding Solution is loaded into the feeding compartment. All lids are closed and the reaction device is loaded into the RTS500 instrument. The instrument is run at 30°C for 24 hours with a stir bar speed of 150 φm. The pIVEX 2.3 MCS vector includes a nucleotide sequence that encodes six consecutive histidine a ino acids on the C-terminal end ofthe target polypeptide for the puφose of protein purification. Target polypeptide is purified by contacting the contents of reaction device with resin modified with Ni²⁺ ions. Target polypeptide is eluted from the resin with a solution containing free Ni²⁺ ions.

Example 11 Cellular Production of Target Polypeptides [0295] Nucleic acids are cloned into DNA plasmids having phage recombination cites and target polypeptides are expressed therefrom in a variety of host cells. Alpha phage genomic DNA contains short sequences known as attP sites, and E. coli genomic DNA contains unique, short sequences known as attB sites. These regions share homology, allowing for integration of phage DNA into E. coli via directional, site-specific recombination using the phage protein Int and the E. coli protein IHF. Integration produces two new att sites, L and R, which flank the inserted prophage DNA. Phage excision from E. coli genomic DNA can also be accomplished using these two proteins with the addition of a second phage protein, Xis. DNA vectors have been produced where the integration/excision process is modified to allowifor the directional integration or excision of a target DNA fragment into a backbone vector in a rapid in vitro reaction (Gateway™ Technology (Invitrogen, Inc.)). [0296] A first step is to transfer the nucleic acid insert into a shuttle vector that contains attL sites surrounding the negative selection gene, ccdB (e.g. pENTER vector, Invitrogen, Inc.). This transfer process is accomplished by digesting the nucleic acid from a DNA vector used for sequencing, and to ligate it into the multicloning site ofthe shuttle vector, which will place it between the two attL sites while removing the negative selection gene ccdB. A second method is to amplify the nucleic acid by the polymerase chain reaction (PCR) with primers containing attB sites. The amplified fragment then is integrated into the shuttle vector using Int and HTF. A third method is to utilize a topoisomerase-mediated process, in which the nucleic acid is amplified via PCR using gene-specific primers with the 5' upstream primer containing an additional CACC sequence (e.g.,

TOPO^® expression kit (Invitrogen, Inc.)). In conjunction with Topoisomerase I, the PCR amplified fragment can be cloned into the shuttle vector via the attL sites in the correct orientation. [0297] Once the nucleic acid is transferred into the shuttle vector, it can be cloned into an expression vector having attR sites. Several vectors containing attR sites for expression of target polypeptide as a native polypeptide, N-fusion polypeptide, and C-fusion polypeptides are commercially available (e.g., pDEST (Invitrogen, Inc.)), and any vector can be converted into an expression vector for receiving a nucleic acid from the shuttle vector by introducing an insert having an attR site flanked by an antibiotic resistant gene for selection using the standard methods described above. Transfer ofthe nucleic acid from the shuttle vector is accomplished by directional recombination using frit, HTF, and Xis (LR clonase). Then the desired sequence can be transferred to an expression vector by carrying out a one hour incubation at room temperature with Int, HTF, and Xis, a ten minute incubation at 37°C with proteinase K, fransforming bacteria and allowing expression for one hour, and then plating on selective media. Generally, 90% cloning efficiency is achieved by this method. Examples of expression vectors are pDEST 14 bacterial expression vector with att7 promoter, pDEST 15 bacterial expression vector with a T7 promoter and a N-terminal GST tag, pDEST 17 bacterial vector with a T7 promoter and a N-terminal polyhistidine affinity tag, and pDEST 12.2 mammalian expression vector with a CMV promoter and neo resistance gene. These expression vectors or others like them are transformed or transfected into cells for expression ofthe target polypeptide or polypeptide variants. These expression vectors are often transfected, for example, into murine-transformed a adipocyte cell line 3T3-L1, (ATCC), human embryonic kidney cell line 293, and rat cardiomyocyte cell line H9C2.

Example 12 Haplotype Analysis ofthe HRMT1L3 Locus [0298] Marker rs876594 is significantly associated with breast cancer at the allele and genotype levels (P < 0.05). Weak LD pervades across the region, although a strong LD is observed between 917602 and 917564 (r² = 0.79). Pearson chi-squared statistics indicate a moderate association between haplotypes and breast cancer after low frequency haplotypes are removed from the analysis. Haplotypes GAGCC, GAATT, and AAACC contribute most to this relationship. Odds ratios and score tests indicate that individuals carrying haplotypes GAGCC and GAATT are significantly less likely to have breast cancer, while individuals with haplotype AAACC are significantly more likely to be affected than individuals with other haplotypes.

Statistics [0299] Chi-squared statistics are estimated to assess whether 1) alleles and genotypes are associated with breast cancer status and 2) marker genotype frequencies deviate significantly from Hardy-Weiriberg equilibrium (HWE). Haplotype frequencies and relative frequencies are estimated, as well as several statistics (r², D', and p-value) that gauge the extent and stability of linkage disequilibrium between markers in each region. Chi-squared statistics and score tests are estimated to determine whether reconstructed haplotypes are significantly associated with breast cancer status (P < 0.05). P-values are estimated for 1) the full set of reconstructed haplotypes and 2) a reduced set that excludes haplotypes with observed frequencies less than 10. Results are presented by chromosome order based on NCBI's Build 33.

Results

Summary Statistics: Alleles and Genotypes

SNP Location

Allele by GYNGroup

Genotype by GYNGroup

Genotype OC: Test of Hardy-Weinberg Proportions

All

Control

V

Summary Statistics: Linkage Disequilibrium

PHASE Haplotype Frequencies

Linkage Disequilibrium Between Markers

D'

P-value

Haplotype by GYNGroup

PHASE Haplotypes (All)

Pearson Chi-squared Test = 19.2426, DF = 16, P-value = 0.2563 Permutation Test P-value = 0.14

PHASE Haplotypes (Low Frequency Excluded)

Pearson Chi-squared Test = 16.0351, DF = 8, P-value = 0.04188 haplo.score Haplotypes

[0300] [0301] Provided hereafter are SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 and HRMT1L3 genomic sequences (SEQ ID NO: 1, 2, 3, 4, 5 and 6, respectively). Polymoφhic variants are designated in H PAC format. The following nucleotide representations are used throughout the specification and figures: "A" or "a" is adenosine, adenine, or adenylic acid; "C" or "c" is cytidine, cytosine, or cytidylic acid; "G" or "g" is guanosine, guanine, or guanylic acid; "T" or "t" is thymidine, thymine, or thymidylic acid; and "I" or "i" is inosine, hypoxanthine, or inosinic acid. SNPs are designated by the following convention: "R" represents A or G, "M" represents A or C; "W represents A or T; "Y" represents C or T; "S" represents C or G; "K" represents G or T; "V" represents A, C or G; "H" represents A, C, or T; "D" represents A, G, or T; "B" represents C, G, or T; and "N" represents A, G, C, or T. [0302] Following is a SPUVE genomic nucleotide sequence (SEQ ID NO: 1).

SPUVE REGION GENOMIC >11: 86191401-86289500

1 ctggctaatt ttgtattttt agtagagatg gcgtttctcc atgttggtca agctggtctc

61 gaactcctga cctcaggtga tctgcccgcc tcggcctcca aaagtgctgg gattataggt

121 gtgagccacc gcacctggcc ctttcttgct acttttgaaa tcatgtgcaa ataaatgttg

181 ctcaccagaa ggatgtgcag gctgtggccc aggcctttta gagagggaag tttctYtggg

241 agggcaggac tgagatcttc attttatcca tgtcaattca caagctcctg tgggaaacat

301 tagtcttYtc aggtgaagaa atgggtaagc ctcaatggaa tcttgcaata attttcagac

361 atcgctaggc ccccaaaatg tgtaattttt ctgcagattt tcactggctt tgctcttgtt

421 tctattttat cctatgtatc ttccttcaat tactcacaaa atcattaggc tagaaaagta

481 tcacagtaat tataactcat ggttatggag aactctagct agtaacaggg aagatggaca

541 caatacaatc ctgtatttgt tttttttttt aaatatggtg ttttgtgcat atgtgtgtgt

601 gtgtacaggc acacatataa acaagagaaa attctgaaag aagaaacaac agaatgctga

661 aacatactta tggaggaatt gtgggtaatt ttacttgatt tttctttata actctgtatt

721 gcctaaatta ttacaatcat ctttcattac ttcccccccc aacatacctt tttaaaagct

781 actctatttc tattttgaat ggaaataaca atacttgaca aagtctttgc tgttaccaag

841 gacctttata aaagctaaat aatcttagct gagctcataa tgtccctggg aagttggtat

901 catctttata ttcgttttat agatggctca gagcaactgt cgtgtgtgaa gtcacagcta

961 ctaaatggca agattgagat gcaaataggt_j atttttgatg tcaaaggcca tgtcttttcc

1021 actctgacat agctgctctc tgtaagaact ttcagcattg tgtcctcagt ttcaattaac

1081 aattactcta tggcatggtg ttccaggggg ttcaaggatg aaaattctgc cttccaagaa

1141 ctcacaatcc agaggagggg ttctcaacac cagttgctca ctagattctc tctagggagg

1201 tttttcaact cctagtgcct ggctcacacc tcagtgtttt cttaaaactt cccagatgat

1261 ccagtgagca gccaagatga gaacaactga tctgctgtgg aaatggcaca tctataaatg

1321 cacagatcct gtgaaagaca atatacactc aattatgaca attcactgct ttgtttccag

1381 taattgcttc tggcatttta tgggtcttgg tatgtggatc tctttgcatg gatgtcatga

1441 gaatttaaga acataaacag catttagagt ctatctttga aattagctgg aaataacttt

1501 ttcttcctct cactacatat gtagttaggc aggaccatgt agcaaagaca actctaaaca

1561 tgggactctg aagacttagg tccagcagtg gctcaagctg taagatttgg gacaagttgc

1621 ctcccctctc tggctctcag tttcttcctc tgtaaaatag aagaataaaa ttagatgctg

1681 ccccaaggtc tccccagctc atatttccta tgattctata cattatataa ctctagattg

1741 gttttttttt attatactct aagttttagg gtacatgtgc acattgtgca ggttagttac

1801 atatgtatac atgtgccatg ctggtgcgct gcacccacta actcgtcatc tagcattatg 1861 tatatctccc agtgctatcc ctcccctctc cccccacccc accacagtcc ccagagtatg

1921 atattcccct tcctgtgtcc atgtgatctc attgttcaat tcccacctat gagtgagaat

1981 atgcggtgtt tggttttttg ttcttgtgat agtttactga gaatgatgat ttccaatttc

2041 atccatgtcc ctacaaagga catgaactca tcatttttta tggctgcata gtattccatg

2101 gtgtatatgt gccacatttt cttaatccag tctatcattg ttggacattt gggttggttc

2161 aaagtctttg ctattgtgaa taatgccgca ataaacatac gtgtgcatgt gtctttatag

2221 cagcatgatt tatagtcctt tgggtatata ctcagtaatg ggatggctgg gtcaaatggt

2281 atttctagtt ctagatccct gaggaatcgc cacactgact tccacaatgg ttgaactagt

2341 ttacagtccc accaacagtg taaaagtgtt cctatttctc cacatcctct ccagcacctg

2401 ttgttccctg actttttaat gattgccatt ctaactggtg tgagatggta tctcattgtg

2461 gttttgattt gcatttctct gatggccagt gatggtgagc attttttcat gtgttttttg

2521 gctgcataaa tgtcttcttt tgagaagtgt ctgttcatgt ccttcaccca ctttttgatg

2581 gggttgtttg tttttttctt gtaaatttgt ttgagttcat tgtagattct ggatattagc

2641 cctttgtcag atgagtaggt tgcgaaaatt ttctcccatg ttgtaggttg cctgttcact

2701 ctgatggtag tttcttttgc tgtgcagaag ctctttagtt taattagatc ccatttgtca

2761 attttgtctt ttgttgccat tgcttttggt gttttggaca tgaagtcctt gcccatccct

2821 gtgtcctgaa tggtaatgcc taggttttct tctagggttt ttatggtttt agatctaacg

2881 tttaagtctt taatccatct tgaattaatt tttgtataag gtgtaaggaa gggatccagt

2941 ttcagctttc tacatatggc tagccagttt tcccagcacc atttattaaa tagg.gaatcc

3001 tttccccatt gcttgttttt gtcaggtttg tcaaagatca gatagttgta gatatgcggc

3061 gttatttctg agggctctgt tctgttccat tgatccattg acatgattgt atatctagaa

3121 aaccccattg tctcagccca aaatctcctt aagctgataa gcaacttcag caaagtctca

3181 ggatacaaaa tcaatgtaca aaaatcacaa gcaatcttat acaccaacaa cagacaaaca

3241 gagagccaaa tcatgagtga actcccattc acaattgctt caaagagaat aaaataccta

3301 ggaatccaac ttacaaggga tgtgaaggac ctcttcaagg agaactacaa accactgctc

3361 aaggaaataa aagaggatac aaacaaatgg aagaacattc catgctcatg ggtaggaaga

3421 atcaatatcg tgaaaatggc catactgccc aaggtaattt acagattcaa tgccatcccc

3481 ataaagctac caatgacttt cttcacagaa ttggaaaaaa ctactttaaa gttcatatgg

3541 aaccaaaaaa gagcccacgt cgccaagtca atcctaagcc aaaagaacaa agctggaggc

3601 atcacactac ctgacttcaa actatactac aaggctacag taaccaaaac agcatggtac

3661 tggtaccaaa acagagatat agatcaatgg aacagaacag agccctcaga aactctagat

3721 tgttaaaaag caagtggtta gtctcagata agaaatttaa aaccgccagg catgtggctc

3781 atgcctgtaa tcacaacact ttaggaggcc gaggtgggtg gatcacctga ggtcaggagt

3841 tcgagaccag cttggccaac atagtgaaac cctgtctcta ctaaaaatac aaaattagct

3901 ggctgttgtg gcacatgcct gtagtcccag ctagtctgga ggctgaggca ggagaatagc

3961 ttgaacctgg gaggcggtgg ttgcagtgag ccaagatcgc accattgcac tccagcctgg

4021 gccacagggc gactccattt caaaaaaaaa gaaagaaaaa ggaaagaaat ttaaaacctg

4081 tatatttcaa ttatctattg ctacatgaca aatcatccca aaacttagtg gcttaaaaca

4141 aaaatggttt attttttcaa ttatgtagat tgactggaga ttcttctgca gatcttccct

4201 gggctctcaa gtgcagatgc aggcagaggg agctcaactg aagttgggac acccaagagc

4261 gtcttgctca attggtaatt ggtgctagct attggctgga aagccttggc tctgctccac

4321 atgacttctc atatgccagg aggatacact ggacttcttt ataacatggt ggactcagca

4381 tctcaggagg gtgagagttg aagcttgcaa aaccttttga ggtctcattt ccagaactcc

4441 tgcaatgtct ctactacaat attctgttag tcaatgtaag tcacaggatc atcccaattt

4501 caagagggtg gaccagtaga ccacatcttg atgagagagg cagcaatgtc atgttgcaaa

4561 aggatgtgga caaagggaag catgattcat gggtggccct tattataatt ctccatatta

4621 tttttgcctg gaaatggcat atgatatagt ggttaagagt acagtctttg aattcaaata

4681 gtctagtttc aaatcttgcc agtcacattt actagcctta tcatgctggg caaggggctt

4741 aaatcactct ttgcctgtct cctcatgggt aaattgagga ggatattaat agtgacctcc

4801 tcatagggtg gctatgataa ttaagggtga tcagtcatca aagccctggc acagagtgaa

4861 tgtgtcctaa aagctctctg ctcttcgtac tgatcctgct tttctgcagg aggtgaggga

4921 gccacttcat ccctcaacta agggcaacaa cttttgtctc cctccttctc cacatcagca

4981 tcagttaccc taactgtgac cacttaaggg tttgaacatg gagtccctta accttctgtt

5041 gtagactccg tgggttaaag ttcagttgaa ctgattatca ttttgctcat tcacatacac

5101 agcatctctt cagtgaaagg cccagttttg ggcaccgatc ttaaaacaag gaatgtgact

5161 tacagcctca gtgggaggag tgtgcttctg gcatgaatgg cccctgttgt gccttggtag

5221 gccctggctc ctgaatgcct agttgagcat ggttccaggt gagagcagcc ctccacacct

5281 gggaacccaa ccccacctac atacagcatg ccaccacttc ctggtctttt ctcctatctg

5341 ggcttatgga actgagggct agaggggacc tcagccctca gttgctgagg tcgctgctgt

5401 ggtccaatct gctgttaagt gcctgaggtg cacagactcc ctaggtcaag acttacctgt

5461 gacttgacct gtgacttgac catatgttct ctggaatata tgacctaagc tttctccaag

5521 gcaattaaac catactcagc agtgtgtctc aaggctttgg agtcaggaag acatgggttc

5581 aaatccctat gttgacacct atagcatcat gacttagggc aagcggatat cctcactgag

5641 cctctcagtt gtttcctctg taaaatggga tagtcttttt tttcctttgc agggttgctg

5701 tcaagattag aagtaagtat ataaagcaca gagtatgaat atgaggagga ttaaattaca

5761 taatttgcac aaagtgtcca agaatgcatg taaatagtaa gccctcaagg aaatgttact 5821 tcgctttcag tatcatggtg aatctaagcc tgaggatttt cattaattaa ttaattcatt

5881 cattcaacaa accactgcca atcctgtggg aaatgaaaaa tgtatatcga gttccaaact

5941 gtttgctcca tgaagatagg ggtcctgctt tttgtccctc actctttaga aagttctagt

6001 acaatgcctg gaacacagta agtacagaat aaatgtctgt taaagaaaag ataacatagt

6061 ctctgccata actaagttcg attttttttt tttttgagac caagtctcgc tctgtcgcca

6121 aggctggagt gcagtggcgc aatctcagct cactgcaagc tccgcctcct gggttcttgc

6181 cattctcctg cctcagcctc ctgagtagct gggactacag gcgcccacca ccacacctgg

6241 ctaatttttt gtatttttag tagagacggg gtttcaccgt gttagctagg atggtcttga

6301 tctcctgacc tcgtcatctg cccgccttgg cctcccaaag tgctgggatt acagtcgtga

6361 gccaccacac ccggccctaa gtttggattt gaagaaaaga tgaggaatat acacaaataa

6421 ctataatttc tgatggattg attcaagtga tcagagaggt acaagagtta tggaagcaat

6481 tatgccctac taggggctga gacaaagctt caaaggagag atgcatttac aatgagctta

6541 gagaaatgga tggggcctca aagtgcaata tggtaagaag attgagaata gagggagcaa

6601 agcttaaccc atggctgaaa atgaagctga aaatcagaaa tgaaactcta agtgtctctt

6661 tctctgtctg catgtttata tgtctgtaat tcagagatgc ctcaaaaacc tctcattatg

6721 cgagtatgta gtattttcct acctctggca gtattaccca aattaaatta taaaattcct

6781 taaaggagct gattgtactc tgattgaatt taagatgagt aagctcatat ataaataaaa

6841 cattcctaac atgctctgaa acaaaggaaa atgagccttg aatattttca atgtgaaaaa

6901 ataggtattc ttatagaaac taactcaaaa actttttttt agttatgttt atatgatgta

6961 ggtaaatctt aggcaaacaa aactagttga ataattttag tttaataaaa acagctttgt

7021 tttctctgag ttagaattaa gtataagtat acatttgtat tctacttgag taaggttttc

7081 ctaaatttat ctaggtttac tgataaaata agctagcatt actcctacta aatatttaag

7141 atttatgaaa aatataaatt tgtatttaac cacatcaaat cattattctg acaaacttta

7201 tgtcaactgt aattatgatt tttagtgttt agctagaaga taatttccaa gatgtttagg

7261 taacttaaaa ccttggacta acactaaatt aatgaatgga tgtttaatag atacatagat

7321 catttataaa aagaatactg aaagaatgtt actaagtata atttaacttt atatacgttt

7381 gcctcttatt tttatacact gaagagaagc tatatatgtt tggattgtta acaaatgtgc

7441 ttatttcttg ccactttgaa aattatgcta taaaggacat gtaataagta tagaatgctg

7501 tggaagggtt gtgaaaagga gattttattt atcatggcca aagctggcta aggtttgatc

7561 agtttattta tgagattttc atggtctttg agctattttt acacctctct gtaaattgta

7621 ggtgatggat atgcgaactt tgtcttttct ggtagagatt aactgacttc ctacctccct

7681 gtggaaaacc cgggttggta cctacttgca agttggactg aatcctgtta ccttgcccaa

7741 attttcactt cttccagatt ccttcgatat gtggctacaa ctttccaaat taactttttt

7801 ggtttatcgc ccgctgcccc aatggcattc ctgaggacca aaacccctct atgtccctat

7861 tgggacctta ggttgccatg cagttggcca tttttcctag gatttgacaa aggcctgcaa

7921 accgaagctg gacaacttga tataaatctg gaaggactca ccatcactgc agaccatgca

7981 tgagaaggaa tgatgttcct tgtgcccagg aagctaggga gacgtatgag aagaaaggat

8041 ggcctgttat gtgtaggcaa gtatgccttt agagagcctc ccagtttcct gcctgtaact

8101 cagtgcacca ctgaacttgc tgaatcattc ctgagagatc aaaactggca cagatgtagg

8161 aatgaaaccc acaggctcta aaggagattt cagatatgaa tggagaataa tttagaaacc

8221 tgagtgggca ggcaattgag ggcccaaaga accactggac atctcaacag attccagctc

8281 agggacataa actcatagat caaatgcact atcgactctc acttaacact tagaagcacc

8341 tcttgggaaa agcagacatg accaaatgga catgctctgt tttagctctg ttttgactta

8401 ccaccagata ggatgatagc tcaaaacaga aattacatac agttatagaa aagaaagata

8461 tttgtagatt atttgaaccc attatacatg ttaagtcgct acccttcaat tggatgcaaa

8521 agcaaaacac aatacaaccc caaatcttta cactacagtg atcaaggctg ggggatgtaa

8581 gagatacagc aatcagtgtg cagagtgaga acagaattgc ctgggcttga ggctctagtg

8641 acctaatgtg agcctgtgtt ggtagagtcc tggtggccac agctagtgca gttctgactc

8701 tggggagagg tcaggtgacc tgaccttgac cttcacgttt atgacaattt gagatgtcac

8761 atcaattttt ctaactggga agcagaaaag tgatacaggg ctgtattagt gcaatctttc

8821 tcatgcaata tgaaaataag caagaattcg ggaaaagttt tgttacttgt gacttatttc

8881 ttgtgtatga gaccacactg cttcagagtg aagccttcct gtttctcact atatcttcca

8941 acctatccgt ttccttcttc tttcatgaaa tacttttggg tacttcccta gcatctcaag

9001 ggatcatctg gaaggaaatt cccagccccc cccctttttt ttttttctgt gtgagggagt

9061 gggggcaggt gaggaggagg gacacaggga cacagctggc tattggtcaa agttaaaacc

9121 aacattcctg acagtggagt tctgagctct gcacaagctc ttcaggatgt gttcctggac

9181 taagtgccaa ggactactcc tgggactaag aaaactccag tgggctgtcc tcatcacatc

9241 agactcccat ggatgtcatg tatcttatct aaagccagag caaggcacat gggatcagga

9301 cccacagagg cacgaaggac acttccatcc cttcctctcc ctcttctcca acagtccaca

9361 ccaagtccca cttgaaggaa aagacatacc agatgactgg ggtattcaaa agaggtttag

9421 atcgtaggag aaggtaactc agcctcctcc aacttagaaa atgtctacag aaagcctgac

9481 aagggagaaa gaaccaaaag aaggccagaa agatacctaa tggattcttc tttctccata

9541 gtgacctgat ggagacagcc attccactca gcctcatcca aggacatggg gacacaacaa

9601 gggacctcac gagatcgctt tacagaccag tgagatacaa agtcctcttc caaaaccctt

9661 caggtcactt agacacagaa tctataccaa agtccccaca attcagaccc ctaatctcct

9721 ttcccagcgg cctctggtct ttccaccaaa ggatatttca aaaagtgtac ccataactct 9781 ctccaaactc catgagggag ggttttgaag atggctttct agagtgctgg tcttcaaact

9841 gagctccttc agtctctaga ggtcacaaga gaaacctcag tgtctccacg taagcaatgg

9901 ggaggccaaa cgggatggat aggctcctga tccccagtcc caagtcaacc acagcagtct

9961 atctgtttta tattttgggc ttttgggtaa aattttatct gcaaaaagcc tccaatgcca

10021 gaaaaactat ttttaaacct ttgagctgga ggatgcatct cagtatccct attgcatcct

10081 cacactcagg cagactttga gggaggtggt acatggcaga gggtgggaat gggcactggg

10141 cacacaagtt ccaggtacct cactaacatt attaaaggtc cggataagga tatagcctgt

10201 ctcagtttat agcaactatg aagaaatggt tgtcttgata aaaaaaattt actgttacct

10261 tctcccagta aaataaaact cagaccttcc aaaatttggc ctggaaggag aatctccagg

10321 taaagaatgt gaattagacc tagaaacact tttttctgtt cctctgggtt ccatgtatca

10381 ttttcctctt tggattttct caattgctca gtgtttctac tctgcagcat tcccccacta

10441 tgcctgacag gagaagtgct gttcctcagc atctatctgt cttcaaacat ctttccattt

10501 cctcctaaaa tggcaacaag tcacctccac agattcctca gctgagataa gattggaatt

10561 ttcaagaaac aattacatat taaggggaag taaaatggag ggggagtaca aatcatttaa

10621 atgatgcaac tttcaagcac atggctctga tccacctgaa ctttcaagca tgggagtctt

10681 attccacctg aactgaatta ttccccaggg atttcacccc ttctcatttc atgtgggatc

10741 catgagtggc tgtaagctag ctatccaaag ggccagatca cctccagagc ctttgcttaa

10801 gccctcactt caaaactccc atcctgttgc cacccccgcc cccaggaact tgactctttc

10861 catggacaaa accaaaaatc agtcatctct tcttcctacc taaggttggt ccggaggcac

10921 atttcttctg cagggattgg caaggaagat ttcagtcttc aaggtagatt tttcactata

10981 aacattgata tgactttatc ctttcaggtc agagtctatc attgccttaa ttcttttaaa

11041 accagatggg gaaattgtaa attgaaatat aatgtttatg aagagcatta tatttggcct

11101 gaaggctgtg agaggtaggg tgaaaatgtt tttatgaatc cctggaactt gaagtttatc

11161 ttaatccctt accctctgtc caggtctgtt gctgggcctg ggcaatggat gcgtttttca

11221 gtaataaaga gaagaatttg aagttccaac agatgattca ggaaatgagg aaagatgact

11281 agggggtggg tgctacataa agaaggaatt tgaagacagc aggaatatct caaaatggac

11341 tttggcatga ctgttataaa ttcttcctct aactcctcta cagaatcttt aataaagtct

11401 acaatgctct tttgtacatt tgtgcgagtg aattctctta ggcattgact ttcatgtcag

11461 gttgggtcat tcttggtgca acacaaaggc ggcactggag ggaaacaaag tgtggaggca

11521 aatgggccac gagactttaa gtcctcagga aacagatgtc aggggtgggg gaatggtttc

11581 cccaggctgt gaaacggaga tgtgaggctt gtgtttggct gcaacttgtg ggtccagcag

11641 gctctagctg accagaacta caacatgata aattgtcatt tcaatccttc actggctacc

11701 cattgtctaa gtccatactc cttggcagga gaggtgctgc tcctccaaac tttcttcctt

11761 caaacatttt ttccattttc ctctaaaaat ggcaacagtt ccctttcaca gattcaatag

11821 ctaagactgg aattttcaaa acaactaagt attggagagt aaaaggggaa aaaaagtata

11881 aatcatttaa atgatgctac ctcctgcaat agggctctga gtctttgtat ggatgataca

11941 taaagccctt tcaaatctgg cctgccacct ctccattgtc atttctccca tacactgcct

12001 tgccactgca tgctacagca ttaccatttg caagaaacct aaatgacgac actctaaccc

12061 caccaaggaa aacaaattac tcttctctgt ctcttccgag catagcattc cagatcattt

12121 tgcataaata tttattgaca tgcttggctc tcctaaaaga ttttgtgagt ttccaacccc

12181 agaacccact gagtgcttaa aaagtagtag aatctcaatg aatgtttgtt gaattaaaac

12241 gattccaaag attgatgtta aaacagaaaa ggaacagaca gacagagttg gaacggcaat

12301 tctgccactt actggcttga caactttgga ccagttcctt aatctctcag tgtcaactgc

12361 ttcatccatc aataatggta ctttgtagag agaaggtgaa agcatataaa gtatctggtc

12421 ccagtggtcg ctcttaatta gtaggccagg ggcttcccag atttttcatt atcagcaatg

12481 aaatatttca tagaaccaga taagagcaga gctactgtaa cttaggggtg cagcctcaga

12541 gccccacctg cttagctaca cccacatctt gacctactca ctcccacccc agaagaaccc

12601 caggactccc agagcatgga gtaaaatcta ctgtcttaaa acagcatggg aggcatacaa

12661 ctagtagtat gtgagatgat tttaagtggc ataaagacat aacattaaat aatactgata

12721 ccaataactt taaaaaagtt attctctctt caattctctt ttaatttttc tgattctttt

12781 gggggaaagt ctcagtttgg ggtcaataca tctttaactc ctctctttct cctcctaggg

12841 tcccaatatt aaaagacagc caaccacaag ctcagaatct ttagccaaca atagtaccta

12901 gctagaatta atgctatgaa tttgtgcagt ttccatctct acctatatca tattctgtat

12961 gtttggacaa attatttgac aacaaacttc cttcattcat gaggattaac atggatttat

13021 tctgaatgta tttattgagt gacttctatg tgccaggcag catggtggaa tacagtggtg

13081 aatcaggcaa atgagatctt cattctcatg gatcttccaa tctggaggga gatctagata

13141 aataaacaga caatttattt atatactgtg ataagtgcca ctgggggcat atggtgtgct

13201 gggcagacac tttagaggga tgcctaactt ggacttcggt gagggggtag gcaaagaaat

13261 atttttttaa aaaaatagcg tctcagttta attctgaagc agtagtattt gatcaagaat

13321 gaggagagga aaccacatgt acaaaggtct agatgtaagg aacactgaaa atgttgactt

13381 cctagtatat gtctggaaca tagcaggtat tcaataaatg gcagcagcct ttagaactac

13441 tacagatgag atggggcatg ttcaggatgg tatggctgta gaccctatag aacttttaca

13501 atgtccttag cctccaaagg tattagattt atctctgtgg cctcagttcc tggcacatag

13561 tagataatca gtaagtgttg aaaactgaat aatcaaataa ataaatgagt gaataaatga

13621 atgaataagt aattattaat ttctgtctcc tcctaacgac ctcccatact agaagccaca

13681 ttctcactca gactttacct agaatagtgt ggttccctcg cactgtagag agagtgaggc 13741 tgcagcctgg ttttgacttt ggacttggga gatatccact gggttcatct ggaatcatgt 13801 ggcctcctcc cctctaacag aggagagagt atgctttttt ccttcttata acactgatgc 13861 taatgagatg cacgtagatg attcttgttt gaaagtctgt ctgaatgaca tctatttgtc 13921 atcccagaga cccacacaga gcttagcaat tggtagtatt gtgaaaacaa taacagcaac 13981 aataaaagcc aaacaaacaa aaaagagagt ggctgtgggg ctgccttatc ttctggagcc 14041 atgtctgatt gtggcttatg gacaaatgga gcaacttagc aggtggaaga gcattaaaaa 14101 cctgagaaca agttataggg aagtctgaag ctaatagtca tatactgatg agttaatgaa 14161 ttaatgggtt atcatgggcg taggaccaag gctttgagag agacctgggc tagcacgctc 14221 agccgctttg ccatgtgata ccctataaca ctttgggatt ctgcagagtc cccaccagca 14281 agaagaccct caccagatgt ggccccttga ccttggactt ctctgcctcc ataactatca 14341 gaaattaatt cttttcctct agaaattacc cagtttgagg tactctatta taagcaacag 14401 aaaatggact aagacactgg gcgtcgtgct aagtgctgta tgtatgttac ttcatttaac 14461 ccccgcaagg acccttagga atagagactg atattatctg cattttacag gtgagaaaac 14521 tgaggcttgg agagtgatgt gacttgccaa ggtcacactt ttagacaggg atagcttgga 14581 tcaaacacag tttgtgtaac agcagagctg gtactcttaa cctcttaacc acagtcccat 14641 aagcgaaaaa gggagtgggg ttcagcatat gccttattag aacactgaat aaacatttat 14701 tcagaaatca gagaaaaata taagaaacag attgaagtag agctagccac tcaaccaatc 14761 ccaataatag aatctttttt gttttgtttt gttttctatt ttgagccaca ttacctcaga 14821 ttgcagtgtg gcattaacta tcagtttagt ctttcttaat ttccaataag tcagttttca 14881 ctgtggcaac aaggtcagtc cctaaaagca gagactgagt tgggagttat ttctgcctct 14941 ggaattataa aatggcccct tactttgcaa ttttttccta ttttgcagaa tgacgtctac 15001 ttcttctttc caaatctcag cacccacatg ctagagaacg atgtgcagac tattaacaaa 15061 atattttctt tagatccatc ttcaaatccc aatgtgtgat tggcctgcag aaccatcact 15121 acaccctcca ggacttgttc ctttgaagtt aggccccaaa tatgtgcctt caagattcac 15181 cttgaacagg aataatttct gtcattgatt aagggctaat caatgtgcat ggagcagtca 15241 gaatcaggag gcccagctgg aaccactaag gtccagtggg agcccgaccc agaatccaaa 15301 gctatgatgc agccaggcac tctccatttc tctctgctgg cttcgttctc cctccccaag 15361 cttctcagtg tcactgcaaa aggtcatgca gctgctatga ttagcatgac tacaaatctc 15421 tgttatctaa tctcagctgg gccctcagtg acactcagaa gtttttactg atcctgagtg 15481 actccccatc acattcccca tggcacattt tccaactgtt ttccttttgt taagccccca 15541 acccactcca gcacccttac ccacatccct ttccttgctt agcagattgg ggttgatgtc 15601 cttctttccc attaaaaact tcctcatttc ttcccatcct ttcctgtctc ctccctgccc 15661 tctcagggag gcccatcccc taggctttat gagatactct cccccatccc taaccctagt 15721 cctaaagatc atactccctg tctcttcccc ttgttctcaa accttatcct tcagcttccc 15781 cagcccatca cctcagttta taaacaggtt ccagggctcc ccatgcaaat aaatgcagaa 15841 atgaatcaac aactattttt ttttcagtgc tttcttccca aaacaccatc ccaactttcc 15901 ctttaatagc tattttcttc tcttcacctc ttggacttta tagttttaaa ttatgtaagt 15961 aatctatgtt catggtagaa aagttagaag ctgcatattg gcaaaagaaa aaaatctgcc 16021 ataacccctc aggaataact ttgttatcat cttgaaatat atcttctaaa ggtttttcca 16081 tgcattcatg tacaaaaata ggttaaactg attttatttt attttatttt attttatttt 16141 at^'ttttttat tgatcattct tgggtgtttc ttgcagaggg ggatttggca gggtcatagg 16201 acaatagtgg agggaaggtc agcagataaa caagtgaaca aaggtctctg gttttcctag 16261 gcagaggacc ctgcggcctt ccgcagtgct tgtgtccctg ggtacttgag attagggagt 16321 ggtgatgact cttaacgagc atgctgcctt caagcatctg tttaacaaag cacatcttgc 16381 accgccctta atccatttaa ccctgagtgg acacagcaca tgtttcagag agcactgggt 16441 tgggggcaag gtcatagatc aacagcatcc caaggcagaa gaatctttct tagtacagaa 16501 caaaatggag tctcctatgt ctacttcttt ctacacagac acaggaacaa tctgatttct 16561 ctatcttttc ccacatttcc cccttttcta ttccacaaaa ccgccgtcgt catcatggcc 16621 cgttttcaat gagctgttgg gtacgcctcc cagacggggt ggcggccggg cggaggggct 16681 cctcacttcc cagacggggc ggctgcgggg cggaggggct cctcacctct cagacggggc 16741 ggctgccagg ccgaggggca cctcacttct cagatggggc ggcggccggg cagagacgct 16801 cctcacctcc cagacggggt cgcggccggg cagaggcgct cctcacatcc cagacgatgg 16861 gcggccgggc agagacgccc ctcacttccc agacaggatg gcggccggga agaggcgctc 16921 ctcacctccc agactgggca gccgggcaga ggggctcctc acatcccaga cgatgggcgg 16981 ccaggcagag acgctcccca cttcccagac ggggtggcgg ccgggcagag gctgcaatct 17041 cggcactttg ggaggccaag gcaggcggct gggaggtgga ggttgtagct agccgagatc 17101 acgccactgc actccagcct gggcaacatt gagcactgag tgaacaagac tccgtctgca 17161 atcccggcac ctcgggaggc cgaggctggc agatcactcg cggttaggag ctggagacca 17221 gcccggccaa cgcagcgaaa ccccgtctcc accaaaaaaa tacgaaaacc agtcaggctt 17281 ggtggcgcgc gcctgcaatc gcaggcactc ggcaggctga ggcgggagaa tcaggcaggg 17341 aggttgcagt gagccgagat ggcagcagta cagtccagct tcggctcggc atcagaggga 17401 gaccgtcgaa agagagagag agggagaggg agagggagac cgtggggaga gggagaggga 17461 gagggagagg ggaatttttg tctaaactga ttttaaaata aagataaaat aacattctac 17521 attgtatgct gtaacctgct tttctttaat tcagtctact caacatcttt gctttggggc 17581 ctcccagata atacaggata atctcacatc tcaagattct taaactcatt tgcaaagtcc 17641 attttgctat gtaaggtaac atattcacat gttccagcag ggattagaac aaagacatct 17701 ctgggggagg gtggcattat tctgcctatc acaagttgtc cgtagcctag ggaagtggaa 17761 gggagcagag tggtagttgg gggattccag gcacagggaa cagcagagtg tgatgggact 17821 tccttctctc cccactccca aagcctccat gctgataaat atactctctt ttaaaaaaat 17881 aagtttgtag ctattatgga catttttttg tgtgtgaact caatctttct tcttggaaga 17941 tacctttttc ccacagcatg tgattctgga aggtttgtca aggaagaaag gcacatgtga 18001 tcaggctgac tagtcacagt accccactcc ttggggcaca gtaactggtt gaaggatggg 18061 caagtgaccc aaacagggcc aatctgactg tttgtgggag gggcctggtc tggatgctga 18121 gacaaggaag ctctagttgt tgatactttg caaattgctg ataaatactg tgagctctag 18181 aaacgctgga accactgggg gctactttct tacatctaga gaaatcctgt ctaaaaaggg 18241 agccatccca gcggagagaa ttgagagaga gagagagaga gagagatcag aggatatcat 18301 ctgaacattt attccagcgt gcctaaagca gacaagttct agactcttca attgcattag 18361 ccaataaatt cttttttttt tttttttttt gagatggagt ctcgctctgt cgcccaggct 18421 gaagtgcagt ggcgggatct cagctcactg caagctccgc ctcccgggtt catgccattc 18481 tcctgcctca gcctcccaag tagctgggac tacaggagcc caccacaagc attagccaat 18541 aacttctttt tcttcctttg cttgaactaa tttgattcag gtttctgtta cttaaaataa 18601 agagtcttca ctaataaaat attattccat aatatggatg cattaaaata aaattaacca 18661 cattccctaa tgttgagtct ttggaccgtt tccaacttgt actattttaa taataccata 18721 gtaaacctcc ttgtacatat atctctatgc atattactga taatttagaa cacattcaaa 18781 gaaatatatt tagaatacat tctaatgtat tctttagaat acatccaaag aaactcatca 18841 attaagccta ctgcaatctg gctgcagccc cacagctctg cttaaattgc cctctgctag 18901 ggcaccaaac atttcctcat tgcctattcc agcaattctt ttttcatcct cattctgttc 18961 aacctattca cattccttct atctgtaaaa tcctcctggg cttcagtgag tctttctccc 19021 agctcctatt cctacttcca gggttcaatt tgggcaccaa ttctgaagaa ctggtaggac 19081 tactgggagg agtcccagta gttgtgaaca gttttttaaa tcgcaacaaa gcttggcagg 19141 agaatgtgtg atcaataatt aacaatgttt tccaatgtac tgacgcatgg tgggtgggga 19201 aggaaaatgc taaaaattgt agcaagagag ccaaacattt gccattgcta taaccagagt 19261 ttcttaatct ggaggataaa ggttaggaga tgccctgggg atttcaaagt gaccccagag 19321 cttcatgaat cccctggagt tagatgcaaa tattgtgtga tcacatctag gtatctagga 19381 tctccaggaa gatcaagagc catttctata ggacagtctc ctgacctgtg ttttcctcaa 19441 gtggccttgc ggaacttatt gttcggagaa agaaaaagtc aagtgaccca gtaattaccc 19501 atcaaactga tgcatgaaat gacatcggga aaatgtaggt ggtccctgca agattcttta 19561 gggagaaaca caaggtcttc ttacactgcc ctgtgggctg gcccagcatg acttggctga 19621 gtagggaggg agggcaggca agttgagaga aggtacagct gctctccatg atgtgcattt 19681 cattctttaa ctctgttctc ctaacccact cctggacagc tctacctcag cttctcccaa 19741 aactatttct agctctccag tgcccaagaa gcctgcacag tgtactgcca gaggcctccc 19801 tccagctgtg ccccaaagtg cagaagtttg tgacatctgg aaatgtgcac atttgggaaa 19861 cagtgctcag gccagctaca tttggctttg agtatgattt gcttctgccc tttctgtcta 19921 ttgtaggcct ctttaattat ggtggctccg ttaagatctc cttatcttgg tgactatcaa 19981 tgttttgaat tccttgcttt tttcccccca agtttaatga gaaatatttc ctgtcaacat 20041 ttcttctgtc ctctctggtg actgtaactt cagctgttat cttcagtgaa attcattaaa 20101 aaggatgaat atctcatgtt ccaagatcac tagcagagat gttaaatgga agaagattga 20161 accacaggct tcttcatatc ctcttgagac ctcccagaat ccagcctgga aactgtattt 20221 ctaggtattc tgtggtcata gttccacact gcaccttgac agacctctct ggatcccttc 20281 caagaatata atttcttgag accaattcaa tgtcttatta atattttaat ctgcatcctg 20341 tgacccatga aaatctctaa cccgtgcttt ccaaatacca ttcaatcttc cacagagtac 20401 ctatagtgag atatttttct ccccacataa ttacttggag cattgcttca cataaaaatc 20461 tggcattcac acatctcaat ctggcattca gggccctaca gtttgatgtc ctttccttct 20521 agaagttatg tgcatttcat tctttagccc ctacaaggac atgtgctctg gactcagatg 20581 accttagttc agattgtgat gcatatactt cctaactatg tgactttgga gaagctaatt 20641 aatatctcag agtctaagtt tcttctgtca tggagtgact gacagaatta aattgcataa 20701 catcattaag agatttaaat gagataatgc atggaaagca tttagcaaag tgcctggacc 20761 atagtaagtg cttttggtga gcagaatggc ccctcaaaga ggtccacacc ttaatccctg 20821 gaacctgaga aagaaaaaaa actcagatgt aattaaggtt aaggatcttc aaatggggag 20881 attttcctgg attatctgat tgggccaaat ataatcacat gaatccttaa aagcaaggaa 20941 cattttccta atagaggcag aaggatacag aaggaggagt tagaagttag aaagattcaa 21001 aacatgagaa agactcagtg ttgtggccca ctctgaagaa tggagtgggc catggatgtg 21061 gactgcagat agacctttaa gaggtaaggg tggtccccag ctgacagtca gaatggaagc 21121 agggacctca gtcctacaac tctaaggaac aggtttggcc aacaagcttg gaagtaggtt 21181 cttcctctga gcgtccagta agaaatgcag ccctgctaac accttaattt tagcctggag 21241 agacccatgt taggcttctg cctccagaaa ctgtgagata atttatttta gctgttaatt 21301 cgtgataatt tgtgatggca gcaatagaaa atgaatccat tgctaagcaa tattggctat 21361 gatttgccag ccacactggc ctaagattcc ccagctcacc tgccgccatc ttccagttgt 21421 gggaaaatcc ctttcctcaa ataactatct tcaaagcctt gttcagatcc acctctttta 21481 tactgtcttt catgaccctt ctatgagcat gagtcagcca tgagcttcca gagaacaaaa 21541 ttatatgctt tcgtcattcc aaacctattc tgtttgagcc acttactacc tgttgtcttc 21601 ccaactccRt ggaaggacac atctatattt tacagactgt atatttataa gactgttttc 21661 tctgctggct gggaggggaa aggacaatta atactcagag ttttctctgt gtcaggccct 21721 gtgcacataa attattttac tcttacaaga accctatggg gtagagagac acttttttat 21781 agatacctca gaggagaaaa acttatccat gtccaacagc ctccaagagg aaaagctgtg 21841 atctgattcc tggtagattc aggtctgctt gattctaaat ttgttgttat ttccactata 21901 ttgtggtgtt tctcataaat atcacctttg tcatcattac aatgaacatt tgtatagccc 21961 cttagagagt agctcacatg gcaggctttt aaggaaggtt ttattatcct aattttaaag 22021 ttcacacagt ccctgagaga caccattagg atttgagcag gatttcttac tgcagaaaca 22081 gtgttttttc cacgatacca cagctagttc caatcaatgt tgatgaatta aatgttacgc 22141 agcttcgggc ttgtgttctc tctctctctc tctctctctc tctctctctc tctctctctc 22201 tctctctctc tctctctcgt ttctctccct ctcttgtttc tctgtcttga ttatatgtgc 22261 cacacctccc agttctgggt caactgcaaa ttgcttttgt gtcacgctga cttctcccag 22321 attacacacc cagatatagg gaatgataca gattctgaca tcagcttcta aagcctctag 22381 gccgctccac ccacagataa accagatcaa attccccttt gtttaggaac ttctggtcaa 22441 ttttaagtca acatgacttt ttaaaatgtt gtaaaatatc ctcagtattt accattttaa 22501 ccattttaaa gtctagttca gtagtagtag gtacattcac cttgttgcac aaccattgcc 22561 attatacatc tctggaactt tttcatcttt cccagttgga aactccccat ttcccctcct 22621 tccagcctct ggcaaccacc attctactgt ctttctctat gaatttgact actttcaggt 22681 atctcatgta agtggaatca tacaatattt gtccttttgt gactggctta tttcatttgg 22741 cataatgtct tcaagattca tccatgctgt gtcagaattt cattcctttt taaggctgaa 22801 taatatttca ctgtatatat agtacatact gattattcat tcatcaatca atggacacga 22861 ggtgctttca cattttggct attgggaaca atgctgccat aaacattggt gtacacatat 22921 cttatcaagt tcctactttc aattctttgg gatatatctt cccagaagta gaattgctgg 22981 atcacatggt aagtctatgt ttaatttttt tttttgagac agcatcttgc tctgtcgcct 23041 tgggtggagt gcagtggcac taccttggct cactgcatct atgtttaatt tttaaaggaa 23101 ctgtgacact attttccaca gtggctgcaa catttcgatt cccatcagca gtacacagcg 23161 ttctaatttc tcctcatcct tgccaacact ttatgttcta tctttctgat gatagctatc 23221 ctagtgagtg tgaagcagta tctcattgtg gttttgattt acagccctac tgattattaa 23281 ccatttgtat aacttctttg gagaaatgtc tatgcctgtc ctttgcccat ttttcaatca 23341 gttgtttttt ttgttattgt cagtgtgact tttcataagt aaactttaag ttttttattt 23401 caaaaataac acatcaagtg ttaaaaaata aatttaaaat cacatttaat tccaccacac 23461 ggaaaaccag aggaagttac ttttaaatta aaatgttcct agaaatagct taaagatttt 23521 atatctaata ctataaattg agtatattaa atgcattagg gacctactat tttataagca 23581 atttctctgg tttgatacat tttctttgaa aaaagaaaaa agaaacccgt attgcatttt 23641 gcttactatg ttttttaagt ctctagggtt acttgttacc ttcatactcg tttcattaag 23701 tttattacca gataaaacag ggtctacatt cttccttgaa tataaatcag tttcctaatt 23761 ctgtcctcta gaactgtctt catttttctt tactttatac aagttaaggc aaacactcac 23821 ttccaacacc cctgagaact tagatctagc tctgctgatt ctgcaaagtt ctcatttgct 23881 aagtgctccc tagcctgctt tccatcaaaa gttacaatag tgttttcact acttcttaat 23941 tatccatact actgggctct ggtttccttg tgagcaaaag caaataataa ttggtgcaac 24001 tgcatttttc tttgtttaga ttattattct tttctctata gagtttgatt tgacacagca 24061 ttttctgttt ttgtaattat atatgcaaac atttttcccc aaactctaaa cctcatacta 24121 ttgactcctt catttctcag taatccttga ccctatttct gggtgcctca atacaggtta 24181 ctagattttc tcatgcttct cctttttata aagtgagggc attgcttttt tatgctaatt 24241 tcccagatgt gatcctgctt taattaccta caaaattaaa ttaccattta atcaaatttt 24301 atttgtagag attgtgcctc actgtttagt cacagtagag tctattgaat agaccaatta 24361 tacttactga taatccttgg tgaattatta ttacttatta cagtattaaa gtattccatg 24421 agtctatact atatgtataa taataacaaa agtcactttt ttggagtgtt tactatgtgg 24481 taggcatttt tctaagcact tgacataagt taatttatcc caacaaatct gtgataactt 24541 aattgtcatc attttatgat gacactcaca tatagaaata ttaagtatat tgcccaaggt 24601 cacatagcta ataaaagata tggccacagt ttgtacctag gcaggctgag tgtcatgtta 24661 ggtgtttgtt cataggacat gtcaatggct gtctagatat atacatgaac tttcaaataa 24721 gtatgtattc tctgaggagt taccaaatgt gttcatttat tcaaagtgca cttactaagc 2.4781 attgactcaa tgcctccatt atgatacact ccatagaaag agattcagca aaccaatatc 24841 tacacttgag ggaatttaaa tctagctgag atctacagat atagatacga cacaatctag 24901 ctaaggagat ctaagataca gacacgacac catcaaataa caatagaatc aacatttgag 24961 taaaagattg catagaacag cttatctctg ataccagaaa tcacaaagtg ggaaaataat ,25021 tgtagtatcc attttgtcaa gccgtacaat ggacttgcat tagagcatga gtacactcaa 25081 gataaaaagg aaatcttgat actatgaatt tatttgatta aaaaaatact tactgagcac 25141 ctactatgtg tcaggcactg ttcttggtac taattgttaa atgagggaat ggatgcatta 25201 ttgagaaaaa ttacaaaatt actttctctt caataacttt aaaaatagga caatatttag 25261 ttatgcacag aggcaggKag atgagctatg tgatgaaaat tatacttaat gataacggga 25321 tgaccttgaa gggggacatg gcatagccct ctctgtgctg tcccattaag ctacccaggg 25381 agaagtcatt aagtcatctc aggagctcac agaggttcaa agctgctgct ctgtgcatca 25441 ttcaatccag tcctttatgc ctccttttcc tcccaaactt ttttgtagag ccttctggag 25501 ctagatctgt gatcaacaaa ctccagtaca tcctcattgc tctgaccact ccctctcctg 25561 gccttgttga aagttggtta tcccccaagg ccacttcttc acctaaaact tctaaaggct 25621 atggtctctc ttattccaag tgtatctaag ggctaggatg tggagtaagc atcctttttg 25681 ctctaattac tgttttaagc catttgtccc ccactgtctc tcaaaaactg aagctcctgc 25741 cttgagatta caagaatacc ttgtagttgt caaatatcta cctccccaga tggcagtcgc 25801 tcatcccccc tttttcactg aaggctttag ttatgagttc taggtctccc aactaaactg 25861 tgagcttctt gagaacagag acctcctttc ctttggtcat tcctggatct ccagcatcca 25921 gaacaatgct tggaagaaaa caggtgctca gttaacatct gttaaataaa caaatcggtt 25981 ttaaaatata tgttatatgc tacgttcttc aaatgtcttg tttcatttaa tccccataac 26041 catcttacca ggtattatga ctattatatt atcttctttt gacagatgag gaaacagagg 26101 ttcagaagag ctatttgctc agagtcacaa aactgatgca aattgtatta gtcagcatgg 26161 gttgctttaa caaaatacca tagactaagt ggcttaaaca agagaaactt actttttcca 26221 caattctggg ggctgaaagt tcaagatcag tgtgcacagg gagagagaaa gagtttaacc 26281 ctaattactt tcttaaagac accatctcca aacacagcca cactgggggt ttggaattca 26341 atatacattc agggagtagg aggaacaaga atattcagtc cataacactg acagagccag 26401 gatccaaacc tagacttgtc cagctccaaa gcctacatcc taactgctga ataaggatgt 26461 catatcgcct ctgggtccct cgctctgccc ctgtcctgaa ccactacagg ccaggcttca 26521 tgcattgccg ggatcatctg tctggttctc tcacggcaca cattctcctt ggagttggga 26581 gctaatggtg caaggcctgt cttcgcgctt cagtacatat gtgacctgga gccaataact 26641 taacagctct ggatgtgcct ccatttccac ctctgtaacg gaagatgatt ctaggaactt 26701 ctttcaggtg ttgagggaaa aaagaaaata gtcttctgac aagtccacta aatgctttat 26761 ggcaaaagca ccacataatt ccaatatctt gttgctatga gtatttccct gaataacatt 26821 aacaaatgtg tagataagca tgagagaaag cagcctccat cccagcaggg tgacgcagcc 26881 tatgggaaag gcccttagag gctgtgacca atattttctg cttctttctc atttgaatca 26941 ttgtgctttt gctttgtttg aatgaagttt tttgttttgt tttttgctcg tatgctctat 27001 ttacaggctg ggaaggatta tcccaagggg attgttctag taggcagcct caggatccca 27061 ctgagatgga tgtcaccctg tctggaagtt ctcaggaatg ttatttaccc acttgagatc 27121 aatggacatc tgaaggtagc ctaaattata ataacagcta acacttatat • agcactatgt 27181 aacaggcatt gttctaagca ctaccgagat attaatgtcc gttatttcca cgataaccac 27241 attctgaagt agatgatcct cctaggtagg tactataata atcattccca tagctactaa 27301 gcagctgagc tgggattgga accaaaggac tttggctcta gaacctgtgc tctgaaagat 27361 gacaactcaa ggcttctcct tttcctgaca tctgttgttc ctctctgcct gtcccgtagt 27421 cacgagtgct gagagatggg gccatcctag aggactggga aaggaagcat gggSccttat 27481 gggtagaggt gagtcaggga gcaccattgt gggaacagaa gcagaagcca gaagtctgtg 27541 ggacctgcag tcaccatcta acagggttgg ggctagtccc cctccagggt tcccagatca 27601 accctgtggg ttcccagatc actaaccagc ctgcattgtc actattagct caattatgtc 27661 ctccaggggg cagtgggttc ctccagggca aggctggtgc ctaggtcagc tcagtggtcc 27721 ctctgcagac agtggccaat ggcagtaRgg cagggaactg ggccatcacc tgaactattg 27781 tgatcctggg ccctaaaaca atgcactcac agcccaagtg ctcatgaatg ggtagatgaa 27841 ataggccagg aaacaccaca ataagcactt atataatgtt tctttagtat ttctaatttc 27901 tttacctttt atatgtttct gctccacaca aaggccctta aacttgaatc acctgaggag 27961 tttggtaaga aggcccaaaa ccactgagat tctgaatcag tagttggttt gtgttttttt 28021 tttcccccYg aRacagagtt tcactcttgt tgcccaggct ggagtacaat ggcacgatct 28081 cagctcaccg caacctccgg ctcccaggtt caagcaattc tcctgcctct gcctcccaag 28141 tagctgggtt tacaggcatg tatcaccacg cctggctaat tttgtatttt tagtagagat 28201 gggtttctcc atgttggtca ggctggtctc gaactcccga ccttaggtga tccacccacc 28261 tctgccttcc aaagtgctga gattacaggc atgagccacc acgcccagct ggttcatgtg 28321 gttttaagaa acattttact aagggcccca tgcaatggct catgcctgta attctagcac 28381 tttggaaagc caaggcaggt ggatcacttg aggtgaggag cgcgagacca gcctgggtaa 28441 catggtgaaa tcccatctct ccttaagggg aaaaaaaaaa aaaacatttt tctagaatat 28501 aatatacaac cagaagtact cataagtgta taccttacta aacctttgca aactgaatat 28561 acctatgtac ccagtaccta gatcaagaaa cagaatatta tcagaaaagt ttttggacct 28621 ttaaacaaac atcatcatta aataaacaac atcccagtaa ttctcatgca ggtcccctga 28681 aggctgagaa acactacagg agtaatgagc agtaaaactg aaagcggaaa cgactcgtgt 28741 gcatttttga ggataacaag gacaagataa ctagagagat tagttccgtg gacRctggga 28801 cccccccccc agggacagag taggtggcat tggccttggg gtggggagtg gagaaggcca 28861 actgagctgc caactgactt tttggataca caagaagcag agctcataaa cttccaacac 28921 ctgaagagag accctgagga ttcaatagga gaaaagttca tgaatgccag gtgcaggcct 28981 caggttatta aacagctaaa agcaaacaag ctttcagagc aaaggcagag gggccttatg 29041 ggctttagtc attgagtcac ctacttaaaa tggatgtgtg tccctcctta caggttccat 29101 ctgaaccaga atggatcaag gccttcagag attcattcat tctctttctt tctctctctc 29161 tgtctctctc tctctctcac acacacacac acacatgccc caagacttgc ttttgaatgt 29221 tctttcccat gctccattta gggtctttta ctatgaatca gactcaattt gattcttgaa 29281 ttacctctgc ctttttcctc ctaacttttc ctttcttcaa aattttttga ttcctgatgt 29341 acagacttaa tgacaaaact aaaagttgaa acctgaccct ctacaaaaat taaaatattg 29401 agtgatgaga aaagaagaga tggttgttat cctgattatc acttaatcac tcatcagatt 29461 ctcagaacac tgaaatcagc ctggctcttc caagctgcat ctgtattttc cctcttgtat 29521 taaaagtcct ccagagccta gctgtttatc aagtatagat atagaaaggg gcataacagg 29581 gagtcacttg ggcactggac tttgaatagt ttctctagtt ttctaatgtt aaatcactaa 29641 cagtccatcc aacttataaa actatttgtg ttgtatattc aacagaggga tggaaatttt 29701 ttttttgttt actgggtttg gctcctgaat tctttcccta gaatttattt actgtgggaa 29761 aagggttgaa aacatttcaa aataactttg gaaaggagtt ttctgggccc tgtacagatt 29821 taagatgaat aaaatgagta aactttttgc ctaacttttt gtctcccagc caatcagtaa 29881 taagtctcca tctggtggtc ctatggagag ctcaagtata gttcatgccc agaaacgtaa 29941 catggggaac ttttcacatt acactattga tttattcaat cattcattta ttcaacaaat 30001 tgttatYgag catgaactat gtgtcaggca ctatggtagg tgcagatcac caaatgcaaa 30061 ctctcttccc tggtctctcc tttttatatc ttggtcgggg cactcagata aatgaaggaa 30121 atacagctct ctaaaatcat catccttccc gtccacctgt cccctgcctt cccagtgacc 30181 agttaggaag ttgcataatt gagaaaaaaa gtgattccct ccaaacctgg gtcttctatc 30241 agtgttgttg ttaacatctg tgtttcttca ggatgatttt tatgagtcta atgagggcca 30301 ggaggcttcc tgggcttcac aaatccagct gacattgcag caagcctgca gcctcccggg 30361 aactgttgat tacaagacct gttgattgta ttgtattggg acaaccagct ctggctaaac 30421 cagtacactc atctgctttg cagtatcaaa aatcaagtgt tccacccaga ttcttttcta 30481 attttcaaac ttttgatctc attccaaatt acatgttaca gtagtttgca tcagcaggat 30541 gacagtcact ctggaaaatt gaaggagtgg ctctgctata tgtttaaaaa tatgcacaca 30601 gcagcgtgga ttttggtaac aacttgattc aagctgcatt tgtgccttta acacttttaa 30661 ttattttttt tttgaaatgg agtctctctc ttttgcctag gctagagtac agtggcacaa 30721 tcttggctca ctg'caacctc tgcctcccag gttcaagcga ttctcctgcc tcagcctccc 30781 aagtagctgg gattacagac aggcacgacc acatccagct aatttttgta ctttagcaga 30841 gatggggttt caccacgttg gccaggctcg tctcgaactc ctgacctcag gtgatctgcc 30901 tgcctcaggc tcccaaagtg ctgggattac aggcatgagc caaacacttt tcaagtagac 30961 attttctttt taataaaaca gagctcaaat ttaacagtct tatgatggga ttcaacattt 31021 ttccttcatg cagctcaggt gtgagtacct ggctttaaag caaatccagt atgtgaaaat 31081 ggggatgcgt acccatcagt actggggcaa gagattcact tcacagaatg aatgctgctt 31141 ttctttaccg gaggaatttt catagtattc tctggaaggc ataagctttc ctcataccca 31201 taaacactta gtaaactttt aatttaggta cactctttag ataagtgctg tataaagaga 31261 agattcagat caggcagatg gtgcatgtta tttttcaagc aattacctta tttcaaatta 31321 aatccaaatg atttttcaac atctggttgg cattcagtgc cttgcctaga ttgttctatt 31381 ttaaacataa tggagtctca ctatgctgca gaagctgcaa actgctgggc tcaaataatt 31441 ctcccaactt ggcctcctga gtagctggga ctacaggtat gcatcaccgt gccctgccta 31501 gattgttttg atgtaaagct gcttcaaggc ttaggttaat agttactcct ttgtcacccc 31561 tcagataatc tgtacccttt tcccagactt gaaatctttt tagcatttat gtaggtttgt 31621 actctccagt ttgaatacgg ccctagaaat agttttggtt ttattcattt tatgaggtta 31681 gccatgtgcc aggcccttaa gaaatgcctt aaaaaatatt gcagttgatg gaatgaaaag 31741 aagctgtcac tgttccgaat catgtctttt ggttaggaag aattcatcag aatgagatct 31801 gatcttggtc atagggcagc attttatagt ggcctatact taggctgtct tcatgggcaa 31861 attattaaaa taagaataag aaagaccaga tatgagtcca agccaatcag caatgatctc 31921 tcgtagccag agagattact tcaggaatgt gcaggtgacc ctgcctggcc aatgggaatc 31981 ggggtcagga tagttgttgg aactgatgag ggagacaaac tctcttttct gctggtttta 32041 attctgggaa aatataagtt aaaagcatct gcagattacc ttaaagtgaa accagcacag 32101 aagaaaaact gagtggtaga gaagcccaaa tcctgatgat gtttcttgag ccctgtagtt 32161 caacagttcc aaggctagac ctattttggg gacttttcaa ttaagttaat aggtaaattt 32221 actttttttt tttttttttt tttttttttt tgatggagtc tccctctgtc gcccaggctg 32281 gagtgcaaag gtgcaatctc aactcactgc aatctccacc tcctgggttc aagcaattct 32341 cctgcctcag cttcccctag tagctgggat tacagacatg caccaccacg cctggctaat 32401 ttttgtattt ttagtagaga tggagtttca acatgttggc taggctggtc tcaaactcct 32461 gacctcaaaa tatctgcccg ccttggcctc ccaaaatgct gggattacag gcgtgagcca 32521 ctgtgcccag cctaatttac ttctctattt aggcaagtca agtttgggtg actttttttt 32581 tatcacttcc taacgaaagg tccctgattc ccccatttcc ccaactcttt tttatataaa 32641 ttaccaagac ctaaggtttc tccctccaga atatcacata tccattatgt catctccatc 32701 tcaatgtcca taatctagtt Kgggttctca tgaactcttg cttgaatgtg caaactctta 32761 gttKgtctct cagccttcac tttctcccct tgcacttacc tttccagaag ctgcccgatt 32821 aatccttata aagcacagat attatgaagg cacactgccc aaaagctttt gctgacttcc 32881 attgcctact gaataaagtt caaattcctg agtatgatat ttcagccctt ctatattcta 32941 cctgcaatct ttacctttcc aacttttata ttttgctgca tctctcatgt aatttatact 33001 caaggattat gctttccagt tgggtattca aatttttgaa gcaagtttga tatacgtgaa 33061 cagatgaact tgctatttcc atatccaaat ctgacagctt ctaattcaag tgacaccttg 33121 tccatgaagc cttccctaac accacagctg aaaactgtct ccaccctctg agcagttaca 33181 gccctttgtc ccttcattac tgagctatta cttcctctta tcttcctacg ttttattata 33241 gctgctttat ctagtctgct ttctagaatt tttaactatt agatagtcac tgtcctttca 33301 gcagggtctg tttcagattt aattttttgt gtaccccatc acctcctccc atggtaatat 33361 tccatacatg tttactgaat tggtataaat gaagggatga gaaaggtgta taatagcttc 33421 ttagaaaact tactttttga tgactacttt aacttataaa taaccaatct tattgaccta 33481 tcctaattta tatatagatt tcctgttgaa gttcatccgg acgcttgaaa attggctttc 33541 taaatactaa atttcatact ttccccctat tttacactat taatctgcca gcacaaaagt

33601 aaaatttagg taaatctttg acaaaactca tacaaattct aaactatcat cttgatgaga

33661 ttaagtacca cagatgagtt taattgaaag tgtctcatga tcaacagctc tctttgaatc

33721 atgttaatag aagcaataac atgcatttaa gtagtgtgtt acactttaca aagtgtttct

33781 acagacatga cttcattcct gtttcacaac aacctggtga gatcagtagg gtgggaattg

33841 ttggccctgt tttaccaata aggaaaaggt aaggtctaaa agaggctacc caattagcaa

33901 gtttccataa ctaagtagat gacagaacta ggactaaaac ccaagatctc tgaaccctag

33961 tccagacctc ttccaattat tccacaccac ctaccttaga ctaactgagg taacttcatt

34021 ccctttccag taataggttt agcaaaggat gtattatgac tattgaattc cagccattgc

34081 aatacgagga caggtgtggg gagtggtata aatttgttgc tcctaagaca cataagaaaa

.34141 gccccctttt gattgtctcc tggatataat tatacatgat gtttgcttgt ttctccatct

34201 tgtcgcaagc ctgagggctg agccaatgca gaagaggggg caccaagaga agcagagagg

34261 gagccttgag tgcccctcac ctgcagccac cctgaccttg aacttcttga tatgtatgat

34321 ttttcatttc cttattattt tttaagctag agtgaattgg gattttccat tacttgcatg

34381 taaaagcatc ttaacagaaa caacatagga aaccttataa gagaatttgg gatagagagt

34441 cctgggtttt catcctctct ccaacactct gaacagagaa tgttacttaa ctgtttggag

34501 cctcaggttc ttgccagtaa aaagagggat tcgagctact actgctcagg gttatccggt

34561 caaatgcaag tagtgggaag tatctagcac agtatctagc acatgatgct attattataa

34621 tgattataaa tgatcattat tattaagatg gactccaact atatcagtgc cataggtact

34681 tttttaaaag tgcaaaagta atttggtgca aaagtatttg cggtttcgga ctgtgaattt

34741 taaattatta tcgctaagct caaacacatc tttattaatc aaaataggaa ccattacagt

34801 taacgcattt ttgccaacaa gtaataagtt tgtttattcc tatagcgtaa aaatctgtgc

34861 ttcaggattt gatgaacatt ggagagcatt ttctgcatcc tgctggctga ggaagcgttt

34921 ttcctgcaaa aggctgtcga gatccttgaa gaagtggtag tcggttggtg agaagtcagg

34981 tgaatatggc ggatgaggca aaacttcgta acccagtttg ctcaacttat ggaagcattg

35041 gttgtgcaat gtgcattcgg gcgttgttgt ggagaagaac tgggcccctt tctgttgacc

35101 gatgcgaccg tagacctttc agtttttgac acatctcatc aatttgctga gcatacttct

35161 cagatgtaat ggcttcaccg ggattcagca agttgtagtg gatcagactg gcagcagacc

35221 accaaacagt gaccatgacc ttttttggtg caagtttggc tttgggaagt gctttggagt

35281 gagaagaatc tagttccaac cactgagctg gtcatcatca gttgtcatat gaaatccact

35341 tttgtcgcac atcacaatcc aatcaagaaa tggtttgttg ttgttgcata gaataagatg

35401 acgcttcaaa acgacatttt tttttctcag ctcatgaggc acctatgagt gggtacttat

35461 tgagcttttt cacctctcca atttgcttca aatgccaaac aaccatagaa tggtagatgt

35521 tgagtttttc agcaacttct cgtgttgttt taagaggttc agcttcaatg actgctctcg

35581 gttgttgtca acttccgacg gccagtcact atgctcctta tcttcaaggc tctcccctcc

35641 tttgcaaaac ttcttgaacc accactgcac tgtaccttcg ttagcagttc ctgagccaaa

35701 tgtgttgttg atgttgcaaa ttgtctctgc tgctttacga cccattttga actcgaataa

35761 gaaaattgct caaatttgct ttttgtctaa catcattttt atagtcgaaa ataaacagca

35821 agtaagaagt cattagcaaa aaacataaag tgagaaatgt acattaaagt gatatataac

35881 ataacattta ataatgtatt ccagtatcaa atggcaaatt tcaacaatgc aaaaatcgca

35941 gtaacttttg caccaaccta tactatttaa aactacaact ttacacaaaa ccattttata

36001 gctaactcat cctttctttt cttgtcaggt agggatcaga ataaatgcaa aggttgacac

36061 ctatcatgct tagatcaaga atacccaatc tctgagtgaa cttcatttcc ctgaagcttg

36121 gagatcgttg ggcagaggat gaaagagttg ataataaaat tacagattgt agttggggtt

36181 gggggactgc taccaagact ggaatttgcc ttgaagtcag caatcaaccc ttcaaagcta

36241 ggctaagaaa tcaaaggctt gtcatgtatt tgttttaagt tttcctgcag gaaggttttt

36301 aaggatttaa gagttcaatt ttattacact gagagaggga gagagagatt gctatctctt

36361 gtcctgaaag agcaaatagc ttggataacc tcattttcca aaatgctatt tatacaactg

36421 tgaggtcatg gtagtttagg tagtttagac ttcctgggtc ttcctggatt gtagccaagt

36481 gactttttca ttttcacatt acaagaaaaa ttgtcatgtc atcttggagt ggtgtcacat

36541 tgctgggaag agcccatttt tattggcagc atgatcctca aaccactgta ttacctatca

36601 ccctgctgtt tgatggaatg gacccacttc ttgtctggag agtctatcct caccctgact

36661 gcacacaatt ccccaaacag cacctctgcc agccttgagt agagactaaa tatctgtgtg

36721 ctccaggaaa agccagagga ctcaagattg gcccactaag aaagtgtgag gcttgtgggt

36781 gtagtgacat cagagccatt tattaacagt ttgggtttat gtcttgattt cccaggggca

36841 gggacaacaa tgtgagcaac tacttacaga tcccacagga tcaaggggct ttttcccact

36901 aaatttagtc tgccggaaac ccggataaaa aagtcactcc tccttgaagg aagtccctac

36961 ctgcagctgc tggtgtcagt actggaatct catcccagtg tgaccttcat tgcctctgtc

37021 agtgtgacag gttccacaga gctgtcaccc tgcaaactca cccttcctcc aggagcacag

37081 gcgcagagct gcagtggagg gtacctgtgt ggcttccttg tctgacacag atttgccttc

37141 atctggtaag tcccacctca ctcccccagt tcccaggaaa gggctttctt aaaccagcaY

37201 agccctggaa gggcctctct tgtttcaggt gggagaacca gcccttgtgg cattctgcag

37261 ggctttgaag tgaaaagaac acatggatga ttattcttgt ggtttcccta atctgtgtgc

37321 ggagggcaga aggagccagg tgatcctgtg tttgaaataa aacaggttac tcttctgaaa

37381 aaggaggaag caatttgctt ctgtaagtac aaatcctcct gctgaacccc tgggccagcc

37441 acctctagct ggctttcaaa tgtgacaaat tggtgccatt tccagtgatg gctgtgaggc 37501 acttttcaca agctcacttg tttttcagca gctctcacct ccacaaagag acaaaggaaa

37561 acctagaggc ctagactgtg gggaagaagt gccagaacaa tctgctgaaa gttaaaaata

37621 agtcttaaag tcagctcact gctgtctgtt ttccaaggtc agactgactg atgattttag

37681 tcaaaacagc caaactagct tccctgtgac ctctgttcaa ggtggctccc cgtggcacac

37741 ctgatggcat ccattcatgg tcctactgct cagagggcct atgctgccat gtgtaagagc

37801 tgaaaaataa gcaatgcatg acatcttctt caatgagctt ttataccagt agctattcac

37861 agggttctta tgactagcta aaataatttg agaatcaggc tctgtgcgat atgttaatat

37921 ttggatacat tttctaatga aatccctata atctccttac agccctgtga ggagggtact

37981 ggtcactacc cctattttga agcaggcttt cccaRtgtgc tgattatttt ctgtctgcct

38041 ctct ccatg agttctccac ccttcactac cctgcactgt gctcagaagg ctggtcctta

38101 cagacagcac aacctgactc ccttgtgagc tgactttggt aggcctcggg agatcagagt

38161 aggaagagaa gaggtcaggg tgcttctttc caacttcctc cgtccttggg gagccatttc

38221 ttgcagcagc tgcaactctc catggactac tcggcaattg gaagcaggct tccctccaag

38281 gtgctcatgc tcactgggct ctgggacagc attttctcct ttctgcctcc tgcccagatg

38341 agtgatggct tcccactgct gctagaccct ggatgcctct ctggcttgtt tgttccctct

38401 accctgtctt cacctccata agtagccact tcattaaagt atcatcattt gaaccaatgt

38461 gctattgcca agaccctgaa taacacaccc agccaaaaaa ggtgcaggcc agagatgcaa

38521 actcatggta ttcaacagta ggggaggaga aacataagct gaaaataaaa cgaataaaat

38581 tacaagagct atgagaaagt tacagaaagt gttatgggaa atcaaaggcc aacaaaaata

38641 ctttgtagaa gatgtaacat tgtgttaggc ctttgaaaaa tggacagaat gtagacagat

38701 ggatatgaaa gagtttcaga tatgaacaaa gacagcaagg caaaaaaaaa gcacagagca

38761 catcttggga acagaagtgg ttcaattgta gaagtggggt aaacttacgg atgacgtttt

38821 tcaaactcca ttcttttttt gagacagggt ctcactttgt cacccaggct gaaatgcagt

38881 ggtacagtca cagctcactg caaccttgac ctcccaggct caagcccccc aggtagctgg

38941 gactacaagc acacgtcact aggctcagct aatttttgta tttttttgta gagatgggat

39001 ttcaccatgt tgcccaggct agtcttgagc tcctgagctc aaattctgtt ctttagaagg

39061 ctWctatatt gtgaactgtt acttctgtat tgaaaaaagg attccgtggt caaataagat

39121 tgggcacctt tgagataaac gagcttaact agatttcttt atgcaagact tctcagagta

39181 tttgaaatgg taatatccat atttaactac ctttttttac aggcaattta ttgacctctt

39241 ccagaagtgt gggagggaat agaatttggg aaacacatat tgtccaatag cattctttaa

39301 tcctggggga ctccatggta gagcaactca gaacaccctg tagtggccaa attcagagca

39361 tactgcaaag agttctgcag aaagccagtc aaatgtcata aatcatggac aaatggcacc

39421 tagaatgcca ccatgtagcc atagcgtgag tagtgaaatg taattagcag gccaagtgga

39481 aactgaattt gttatctgac atgaactgta aggaaacaat ggtaaacaga ccctaaatgg

39541 aagttcagat taacattctg gagagtgtga gagccccagt ggtaaaattt catgtacact

39601 cactgtgtcc tgttcctagt ggctggcaag ctaaattatt tctgatctaa tatttttaac

39661 caattagaat tttattcatt aatttaatca tttattaaat taacattaaa taagccttta

39721 caaagagcta ggttctctgc tagactatag cagaaaacta taaagactaa aaaggaaaac

39781 aagacagatt tcctactcat aaggagctct ggactgcttg agtttcaaca tgtaaatata

39841 tataattaca acataagata taattttaat acaaccctct aaaaaacata agttaaactt

39901 acaaatctag caccgaaggS tttggaagcc ttcagagaac agctgatatt tgagcttgaa

39961 ggatgaatag aattttccaS aaagtaaagg agaaacctca taaaagaccc aaattcaaat

40021 atccagaccc cacactgaac cacatgaaag cttactcctt ataaaggagt aaaaagagaa

40081 tccaacattt atggataaat ataaacaaaa attgaaaaca aaataatttt ccataaaaga

40141 tttttaaagt tgtaaagatt tcagaaaaaa aatttccaat ataaaatctt cattttctct

40201 tttgttcttg atcataagat ccagtatgca agttagagta gatcagagaa gccccatgct

40261 ggccacttca aatttggaga cttcaaattt gaccagagaa aatgagaaac acatagttat

40321 tccaaaatgt tcccaatatt tcagtttaca atagtgccca gagcatacag gaaattgcaa

40381 gtactcaagt ctatttttct ttctgataat tttagattgg catattctaa gtaggattag

40441 agtaaagctt ttacttgctg tgcagctctt tttttcctac catatgtacc aatatgacaa

40501 tttaaccSta caataatttt gtatgttaag cttttatata ttacaccttc acatatttac

40561 atttagagtg cctgactacc tatgtttcca aagacttaaa atgagtaatc tatacttaac

40621 aaaaatagaa atttttagaa agttttgaat gtaatacaaa tatatttgtt ttctgtatta

40681 agtgctgtag agatttgagt ggtttatctt gttagatttg tttttattac aggaatttta

40741 ctatgggggt tttacttttt acaaggaaaa ttttaaatta aacattataa gaaaaatgtg

40801 attttgccct aaaaaaacac tgacaaatat ataaaccttg taatattcat ggttcaatag

40861 gtaattgttc aatgaatgaa ctgatggtac catagaggag attggaggag gagacaaaaa

40921 atacaaccat ggctctcatt tgaatctata attcttcctg aattcaatat taaaactctc

40981 ttgcctgtag accagactga agacaagatt tgggggtgtc aacgggagtc ctgggataca

41041 ttttttctta taaagtctgg attaaacttt ttagcatgga taatataaca gtttgattta

41101 ttcatttatt cattcaacaa ttttcaaaaa catttattga gcattcacag tagtaacaat

41161 agcagcagtg atagtaatga taataataat tataataata atacgtattg ccaatttaga

41221 atttactttg tgctgagctc gatgctatgg gttttgtact gattatctca ctgaatcttt

41281 acaacacccc taaatcagtc tcattgtgca gatgagaaaa gtgaggcaca gaaggtcacg

41341 taacttgccc acattcaccc aacgaataaa tgaattctaa gttgaatcca agtcagtctg

41401 accacagaat ttcacatcct ttgctactcc gggatSccat ggtaggcacc gtgggtgccc 41461 caaaattaaa aaatgatgtg gatcatcttc ccgtaaggat tactatgtca taagctcaaa 41521 gactgtaaca gcaggttatc taggttctct actaacagac aagaaatcaa ggccaatgag 41581 tgtggtgatt tacccaaggt cacacagcac ctctatggct aagacacatt tagaatgccc 41641 caccctgtgt tgactttcat tccaattctc ttttcactca ctacacagag ctgaaaaccc 41701 ccacttactg agtaaactac aagatccacg taacacttta ttattatcaa agaaatatga 41761 aaccatatgg aaatgatttt gaaatatgcc catttatctc cttagacata atcctttttg 41821 ataactttca aactgactta aattgttgag gctacatatg gatcttggtc tcataaaaaa 41881 taagcactaa aatt agttg agttgaggtt gagtttagag ttagtgctgg tcatgccacc 41941 ctaagcttcc aagtatcatt cagtcccatc ttgtttcctg ctttggggtt atttaacagg 42001 tcattcgtga gttattacat aactggaaca aaagcaagat agaatcaaaa ggatacttag 42061 agctggagtg acatcagaaa ctgatgcaac ctccttattg tcaggacggg aaaaggcaag 42121 tctgggaagc aatataacac aatggaatcc agcaaaagaa tggggcagac tgggcagagg 42181 tcacagctgt gatcctttgt actgtagtat ggcaccgagt agactatttt aaaactttga 42241 acctcagaat cctcatctgc agaatgaaga aaatcatagc ttctctattt gtcttaaaga 42301 ttacacatag gccgggcgcg gtggctcacg cctgtaatcc cagcactttg ggaggccgag 42361 gcgggcggat cacgaggtca ggagatcgag accatcctgg ctaacacggt gaaaccccgt 42421 ctctactaaa aatacaaaaa attagccggg cgtggtagcg ggcgcctgta gtcccagcta 42481 ctcgggaggc tgaggcagga gaatggcgtg aacccgggag gcggagcttg cagtgagccg 42541 agatcgcgcc actgcactcc agcctgggcg acagagcgag actccgtctc aaaaaaaaaa 42601 aaaaaaaaaa aaagattaca cataataaaa tatactccac agtacctggc atatagtatg 42661 cattcactaa gcatagatac aatttagtcc tagttctgct cccttaattt atgcattgat 42721 tttctcatct atacagtgga tatttttctt cttgtctgtg ttacaaagta gttttgtgaa 42781 cacagtgagg taatgtccag atttttatgc tttgagcttc agctcaaatt ctacctcaaa 42841 gctttcagca cctgccagag tgggaattaa tgattccctc ttccatgttc tctagctcat 42901 gtctgtatcc tgatccagct gatatcttgc tttctcctat atttgatttt gtttatgtcc 42961 attgcataca ttcctcgagc tgaggggtat ttgctttctc tccctgacag cccaaataac 43021 cttacacaga gtggatgatc agaaaatgtg tgggctttgc cctgaatgca ttttgaacaa 43081 ctccattgct acgcatataa aaagtattcg ggaattacaa ttatagagtt gaactgagtt 43141 cttaagaagc agtgaggatt tcggttttgg ttcccccgac cccctcccca ctggggaggg 43201 aaatgggacg agtacaaaaa gaaaagcaaa cctctaatct tagcatgaag acatctgctg 43261 tttacattgg tcatttgtct cagaggtcaa aatacagttc tatcatcgtc cttatggcaa 43321 tcgtgatgac aacctaacag ccaggaagta gcctctcatt ttactcttgg tagctctgag 43381 gaacaacaaa agcttgtggt gcatgttcaa accctgagcc cccgtgggac atctgtagtt 43441 aaagagtcct tcctattagc tctttggata gtgggcggta gtccctgaga ccagatgaag 43501 gactgttgtg ctcttgggcc cttctgtgcc tcagtttttc tctctgagtg atgggaataa 43561 tcatcttgtt ctccatgact ctaacttgaa acattgcaac tactaggaaa aaaatgagca 43621 atgaatgtca aagctgactg aggtggtact ggaggactac actccgaagc agagccaagt 43681 gtgataaata taacaatacc taatatttat taagggcttg ttccatgtaa gaaactctcc 43741 taagcacact atgtatatYc attcaattct taaaagaact ctatgagaaa gtcctggttt 43801 tacagaggag gaaactgagg tacagaaaag ttaagtgaaa agccacacaa ctagtaagcg 43861 tcagaccttg gattggtacc ccatagtcag atgccacagg ccactcttaa ttatgttgct 43921 gtatggtcct cctatatgYa tctctttaat tttgtgccta gcgcaatgtt ttccatgtaa 43981 tatgtgctca atatatattt gttggattga agtgactcta atacaacttg agcatggttg 44041 ataaatctct cccttcttcc cttccttcca gctgcacctc cagttcctct attaagatac 44101 ttacctttta atggtgtttc ttcaattggg agctacagac acttagagat cctcaattta 44161 atctttaaaa tttttataat aaaagataaa cacattctgg atcattggga tgaccatctc 44221 atgccaagta ctgcctcttg attgcagcac ctgtgtgtac tagtctttgg cagcaagagt 44281 taccacttca cttgctatgc taataagaga gaaacagcac aaatacctaa ataatgtatt 44341 agagtcaaga gaaacccatt gcaatgacat atggtgtggg caaaggagat atggtagatg 44401 gaacgaagga aagaggtgag agaattgagt ctgcattggg cacctcacac atcatgagag 44461 tggcagagcc acagggaagt caaaggtact gacgcctcag ctgtcagtac catgcaatgc 44521 tgatagtagt ccaggaaacg ttactaattt caattttatt attctggaag aaaattttta 44581 taaatctgtt ttggttttat ttgcgagttg ttcaaaagct gtaacataag tttatatctg 44641 gttttgtgtc tgtgtgtgtt ttgagacagg gtcttggtct gtcacccagg ttggagtgca 44701 gtggtgatca tagctcattg caacctccac ctcctgggct caagccatcc tcccacctca 44761 gcctcccaaa tagctgagac cacaggcgtg tgccaccaca actggctagg ttttttgtat 44821 tttttataga gatggggttt tgccatgttg cccaggctgg tctcaaactc ctaagttcaa 44881 gcaatctgcc cactttggtc ttccaaagtg ctacgattac aggcgtgagc cactgagcct 44941 ggcctatgtc tctatatatt aatgtgacat tttaaaagaa aacaattgaa gctaagctaa 45001 gaaaaatttg cccttaaaat ggtggaaaat atcagtttcc tttctattta agaaatacca 45061 ggccgggagc agtgactcac gcgtgtaatM cttgctgaga agggaggata cttgagccca 45121 ggaggtctac gctgcagtga gctatgatcc tgctactgca ctccagaatg agctacagag 45181 ggagtacttg tcttgaaaat aaaataaaag aaaagaccac acaataatgt gttcagggct 45241 ttctcatKta aaagtaattg caaacaccaa cgtattaggc atatcagtaa caccttggtg 45301 tgaaatagca ctttagacct tccctttctg agagtagact ttgataggag aaaggaaagc 45361 taagtagctt gatagaaagc atggctcagt gcaaaatctt gtcctaccat tcagtagctg 45421 tgtgattttg ggcaagtcat aaaacctctc caaacctcct gttccttata aaaattagtg 45481 taatctctgc accttcttca ccacaatggc ctatatgtaa agctcttgac cgaaaacgct 45541 caatacacag taatctatac taaataggaa ggctctaaca ctaggacctt aaatggcaag 45601 gtctccagcc tggttaggag aggactcccc gcacaccccc ctaccctggc ccccaaccac 45661 caccaccaag ataacgaccg cttggagtga Ytcagggaag taggcccact ggacaaggag 45721 gtggctccac cagctggtgc cccgatgaag aactgaggcc agtgggctcc ccagccaccg 45781 ccgctcagaa gctgccaagc acccccggtg ctttgggccc cacgcacagc actgagtgct 45841 gtaaggaaat gcaaagcatt ggtggccctg ccatgggaat acaggtttct gttctttgga 45901 ggcaccggag aaactaggag ttcggtcagc accttaaggc gctaaaagtg tacgtggggg 45961 tggggcgcac acaggttctg aaccaattct tcaaatttgc ccagggctcc ccatacacca 46021 ggtgtggccc gcgtccctag ttctaggctg ttgggggagg ggtcgccttt tgtaggggac 46081 ctggtctttt tgcgagctgg cagcgtgctc ccagcagcga aggccgtagt ctcgctcagg 46141 aggccgcgcg ccagacccgg ggatgcgcgg tgttcaaagg gtgacggcgc gcgggtcccg 46201 ggcaggagag cccgccagag ccggtgctgc ctggcgccga gaggcccgga ctggcgactg 46261 ctgccgcgcc accggggccc acctgcgcag ggacgctcgg cctcaggccc\ tctgggctgc 46321 tccaccctgc tccggccgca ggcgagcggc gaggggaggg gggcacggtt tatgtgcagt 46381 ggggcgggcg gcgtccgcgc ggcttccccg aggccggagg cggggcgggc gggcctcggg 46441 tggcgcgggg ggcggacccg ccagctgcct gcgctgctcg ccagcttgct cgcactcggc 46501 tgtgcggcgg ggcaggcatg ggagccgcgc gctctctccc ggcgcccaca cctgtctgag 46561 cggcgcagcg agccgcggcc cgggcgggct gctcggcgcg ggtgagtgcg ggcaccgact 46621 ggggcatccg cccgggcgcg ggagaggcga ggcgccggga ggagcgggac aaagggccgg 46681 gtatgcgcgg ggtagggtaa ctgcgggctg ccggaggcac cgcaggactt cgccagggca 46741 gtcctcgggg ttccaggaca cgggctgggg gcctgaagga gctctgggga gacggcgggg 46801 gctgcaggtc atttggattc atgcagtgtc acccatgaaa cggatgggga aagaagatcc 46861 tgctgtcttg ggtgcaggat gttggttggg aagcagagag agccggctct cggcaagctg 46921 tccttcggcg ggggcgatgg ctacaccccc atgcaccccc ccaacacacc accaccacta 46981 cttYttttcc ttgagttttg catataccgg attccatcaa gttctgaata ttaagtttta 47041 accctgggca tgtgattgtg aacacaccta agcaagcaag agaagtgcaa aagtgcagca 47101 aatacaggct gggaaataga atcttttctc cggagtggtt gtccgtgtgc gttccggggg 47161 tgctaaccct agacactaca gtctgaacta acaacagttg ttgtaagcaa atagttcttc 47221 tgcctgtagg cattcatcac gagttaactt ttaaataaaa gttttaaagt tttaaaagga 47281 gcgggagaag acttgttcag atgaaggaac accaccactc ctctccagaa tacaaattag 47341 gtttgctttc cagcacctca ggagaaagca gctgataaaa atcctgtttg ttttactgcc 47401 cactgggtga caccagtaag aattaagcag ctcagtgtag gtattggaat agggcttgct 47461 tctctcagct cctgaaacta aatttgaggg ctccctgtgc actccttagg aacaggtagg 47521 ccagtgccag aatcctcatc acatggtcat gtgagaaaga attgaattta tagatgaggt 47581 cagctgtggt caaaagccct atgtcaaagt agtatcagga tatttattgc atgttgtttc 47641 aagatcctac ttgtgcatgc gagtatttgt gacaggttta taaccgtgcc taccatgaag 47701 tctgtcagga gtggattgga ggtgaagtgg ggagaaggaa cttagaaaat gcccccagaa 47761 gccactatgt ttatttgtga aagtgtttgc accccatctg cgtacgaaaa ggttgtttca 47821 cttgcagttt tcctagttaa ataaagtcaa gcggtaactt gtcctttcct gtgcctgaac 47881 tgggaaggaa gcctttttcc aaggtgccta atatggatct catttttgta acactgacga 47941 cttattcagc tggatggtta acatggatgc attttctggt tgtagcataa gtgtccatta 48001 atgcatctga gaacattttt gtccccagtc tgcaatggtt aatagtctca ggttctccca 48061 gtaactcttc tcatagatcc cttaggattt catccaccag gcattattca tgcctaactc 48121 ccacagactc cagggaattt gtttctcatg ttctcaatat tagcaggttt ttttgcactc 48181 tgttcttgtt ctgccaggtt tgtcccaggc tcaatttagt ttacctgaaa tccgatagag 48241 aagaggctaa acttcatttg accacaagat tgtgtttagg gttgcttgga cttgtaagtg 48301 ccttgtagtt tcctgtacaa gactgtaatt cttaaacgat tatgtgatta ggtctgtttt 48361 gccttaatag ggtctgtgat tcaggaaaac gagaacaagc ccgactgcag agtattcaca 48421 gagcttggtt cattcttaag catttgcttt aggatttagc atgatttcac cgttccatat 48481 cactgaccac tgattccatg gaagaccctt tgtcatctct ccaaatggtg tccaaaacct 48541 gtatctttgc aaactttcct gccgtttctt tctgtcatta ctgtttatag cggctgcagg 48601 aattcacaat ttgtacaata gagaatacat gacctaagga ttaggttttc cctcccagca 48661 cttgtttgct ataggagtta aatcattctc tcaaacagtg gccctcttga ggagacctgt 48721 gttgttgcag ttttcaagac taaggtgccg tgcaggagac agtagtcact gcatccagtc 48781 tccaaagaga ttgttgtttg catatctgtt aattatgcaa agtcccacca ccaagggcct 48841 atgaagtggc agcatcctca aaaagtataa atattttcag acagtggctc atattgagtg 48901 atggagggtg gactgtgtaa cctatttatg aatcagatac ccaaagctgg aaaaggaata 48961 gtttctgtat tactaagcat ggtgaaaaaa tattttctta ccttcatttt ccattcttcc 49021 ctgccagtta ggtgaaatga tgcacggaaa cacttggttg gaaaccttaa aagataattt 49081 atgtatacca ggaatcttta ttcagcaaaa gtttattcct agaaatgaaa cgttatagac 49141 ctaaattttc ttcatccaga cttaggtaaa agggtgagat ttgaaaatct tcattccatt 49201 tttaaggtgt gagtcttcca ggcagctctg caaggataag gtgattcatt tataagggtg 49261 agagagaatt taaaatcatg taactcatta gttacctttc caggtgtggg attatgaatg 49321 ttttcattac atctgtttat accttagatg agtgtttatg tttaagtaaa cttaaacagg 49381 tatagcacag gcttacccag ggtttataca gatggtaaca ataattattt gtcttctaag 49441 gaattactcc attatcatgt gagttgagaa atgaatgtaa atccaccaac ctaattttaa 49501 agcatcacag ttttgcatca tttgttgttt tattaatgcg gatgagtcag ggcaggctgc 49561 gaatgcctca ggaaagaccc ttaatggaca ggagggttgt ttccccctca ggcttttctt 49621 tggggcctgt cttaagagca tacacacaca gccatccctc cactcagttc ttgaaagctg 49681 ccttctgctg gagtcacaat ttgtacaata gagaatatat gacctaagga ttaggttttc 49741 cctcccagca cttgtttgct ataggagtta aatcattctc tcaaacagtg gtcctgttgc 49801 agactgatca gggaaatctt gtctgccaga tagatgagaa attagcatga ttcattttcc 49861 ttttcctttt cctttccccc tcctttgcct ccaccctcca taattccatg aatcaatggt 49921 cctgagaagt aaatgatagt acagacacta tagtcagcat cgtccctgac ctggacttaY 49981 gtgattctgg aaaattataa tattagggaa tcctggacct aaagaccaga gctaaaaaga 50041 ccagctaaag caatcatctg gttgaggatg ctattcagaa gaatttctaa agcaccctaa 50101 ataaacattt ggtaaaggac taagcaactt aagaagcttg tagctttaat acagacatca 50161 gtttaaaccc atttaagggc ttgagaaccc acagctgtat cttctaattt ctgattagat 50221 attttaaaaa tatctaagcc taatcagttt gaagtaattt gatgggcatt agtttctaaa 50281 agtctgcatt catttctaaa tctgaattaa acttttttaa atgcaatttt ataactttta 50341 gcgttacatg gaagctttaa gcaagatata taatgctgtc agaacaaagt cttatcacac 50401 aagttagtaa atagggttta gtaatgtgga gaacttggaa gcagagttgc aaactaatag 50461 aaattaggac ttattaagtc tctgaaaaat ttattcttca aagttaaagc ttcacactgt 50521 cctgttgggt tagcagtttg tttttttctt atagatggct ggcttctcct tcactcctgg 50581 ctaaatgaac agaattcaag ttgtaagaac tctgaattag taatattcta tcatgcagta 50641 gactctttag cattctctaa caggattctg tgattcataa ctgatcccaa agtttcttga 50701 gacataatca ttcatcattt tgccaaagaa tacatttgat cctctatatt gagaggttgg 50761 agtaaggctg tggctcatga aagaggatat tgtaactgcc atgttcttca tgcacattga 50821 aaatattatc tgtagctgat gataatacat actataatac tacctcatct cctactcttt 50881 ctcccccaag aatcgtattt taaaaacaag aacgcttggc aggttggacc tccgcattct 50941 gtgttttctt tcttaagata agctgaagta aaacttggct taccatgtgc tcaatgtaag 51001 tcacattaac attccccaca ttactcaaag ggaggagaga atggtgcgtt gaagcccaag 51061 atacagccat gtgggagata tatgactcct cctagtccct gtcacatttg gcagggattc 51121 tggtgtgagt ggggcattta gtcacctaga cagcaactta tatagagaaa aggctgctca 51181 agtcctcgat aagcccaagg gatgactcct tagccagtag gtgggaataa tcagaaccat 51241 gccccacaga tctcctaaag ggttgtcatc accacaccca tttcactgcc aagttctcca 51301 ttggagagga ggactcagct agcattggca tccccttcct agtccactta aaacctttag 51361 tcttggcaat attcccaaca agcacataca aacacgtgtg tgcacatatg cgggcacccc 51421 atgttttcaa ggatttaaag aaataattaa atgtatttcc ttcctacaaa agggctcagg 51481 gacccttcct atttggaaag atggagacaa gtagaatttc aaggaattag ggagtcccaa 51541 ggaactggct tttccaggac cttatttctt tcttttccta tccctattct ccctgactga 51601 agtggaagcc aagagaaaaa gtcaagcaaa aaggtcccag aggtgggtgg ggcacacaca 51661 tatgttagaa acacagtgtg gatattggga atgagaatgg gcatgctcag ctatactaca 51721 tcagatcatt gggattttct acttttatat aaaagggagc aaaaggcacc caaagttgcc 51781 agtagatctg tactttcaaa caggaagaga atgagaataa caaaacagtt tcttcctaac 51841 ttctgctgtg ttcccagagc ctcttgagac ccaccccttc cgggtccttg tttttggatg 51901 cttggttgtg aatgagttac cctacctgct gagtcagctt ctattgaacc agaagagtca 51961 gagccactga gagccaactg atgcttaaac atttatgaaa gcactttcag tattcctcgt 52021 tgttgttttt cttgtgggat gattgatctg ggcatttaaa cataccttgc agtataaaat 52081 ccaaacttct ttgtttagta cacatagcac ttcacaatct agctcttgcc tgctgcctcc 52141 accacttcct ctactccacc cttgctgagc taagtgtgat tccccaaatt actcacatgg 52201 ttgcatgttg ctgtgccctt gcacagactc ttgtttccct tccctaagta tccccttctc 52261 tctgtcttat gttatcagac ttcttttcta cttcagcacc catctgaaac atcaggtgat 52321 gcctggaaaa tttctaggca atttgttcat ttagagggta aatttaaatt acatagctta 52381 ctgaatgacc gaagcatcaa ggagggacag ctccacggtg tcacctttac taggactcct 52441 attgcttcta aatggtgggt acatttgaaa agaacgggtg catttgccaa ataatacatt 52501 tggtcctcta tattgagagg ttggagcgag gctgtggcat actatttctc aagcatcact 52561 tctcctagaa ggcctctctt gttcttactc ccacaattgg cctcaagctg tttctctgag 52621 ctaccgcatc atccatgtac atcattgtca ttagcgtcag catgcaacat tcattcactt 52681 ttccattaat acaagcatcc atttaacaaa tctttgtcga gtgctagcac aggcccaaat 52741 ttaagagatt tagttggtaa tacagatata aacaactgaa aaagtaacca atggtaacag 52801 ttcatagtgt tatagctgat gcaatattag agctttagat attgacaaag atcctggtag 52861 tgtacaacat aatccaaagg aagaaggaat attttattag aagcctagcc actctggaac 52921 tcaatatata taatagtaaa ggttgttgta aattcaaagc aaaaaacaaa acaaaacaaa 52981 aaatctcata ccctttctcg agtgcaccat catttaaaaa ccacaggagt ggtggtaatt 53041 gtgacactgt ggagctgtcc ttctttgatg tctcagtcac tcagtaagcc atgtaattta 53101 aattgaccct ctgagtgacc aagttgctct gaaaattttc caagtacatg ttacaatgag 53161 aatgagagaa ggWggaggga aaggcgggga catcatgaag gtagaagagg aggaggttta 53221 gaatcaagca caaagagggc tcaaaattac gtggaaattg gggctggtca gtcagttagc 53281 caggggacta atgactttat gcMtgctact ctgcagtcta ccatcattag ggacatctta 53341 aacatagaaa ggaaggaaca cccaatttca cttcaggcac ccagccacag gaactttcct

53401 aaggttgagc ctttgcgttg aaagtgagac cgttatctaa ggattcctct ccacaccctg

53461 attcctgagg agtgttcaaa gactcagaaa caatgacagg cctgctgctg agctttgctg

53521 tctgcagtaa atgaacgttc agcccttgcc ctcctgacct gcttgtcttt gtttctacag

53581 aacagtgctc ggcatggcag ggattccagg gctcctcttc cttctcttct ttctgctctg

53641 tgctgttggg caagtgagcc cttacagtgc cccctggaaa cccacttggc ctgcataccR

53701 cctccctgtc gtcttgcccc agtctaccct caatttagcc aagccagact ttggagccga

53761 agccaaatta gaagtatctt cttcatgtgg accccagtgt cataagggaa ctccactgcc

53821 cacttacgaa gaggccaagc aatatctgtc ttatgaaacg ctctatgcca atggcagccg

53881 cacagagacg caggtgggca tctacatcct cagcagtagt ggagatgggg cccaacaccg

53941 agactcaggg tcttcaggaa agtctcgaag gaagcggcag atttatggct atgacagcag

54001 gttcagcatt tttgggaagg acttcctgct caactaccct ttctcaacat cagtgaagtt

54061 atccacgggc tgcaccggca ccctggtgKc agagaagcat gtcctcacag ctgcccactg

54121 catacacgat ggaaaaacct atgtgaaagg aacccagaag cttcgagtgg gcttcctaaa

54181 gcccaagttt aaagatggtg gtcgaggggc caacgactcc acttcagcca tgcccgagca

54241 gatgaaattt cagtggatcc gggtgaaacg cacccatgtg cccaagggtt ggatcaaggg

54301 caatgccaat gacatcggca tggattatga ttatgccctc ctggaactca aaaagcccca

54361 caagagaaaa tttatgaaga ttggggtgag ccctcctgct aagcagctgc cagggggcag

54421 aattcacttc tctggttatg acaatgaccg accaggcaat ttggtgtatc gcttctgtga

54481 cgtcaaagac gagacctatg acttgctcta ccagcaatgc gatgcccagc caggggccag

54541 cgggtctggg gtctatgtga ggatgtggaa gagacagcag cagaagtggg agcgaaaaat

54601 tattggcatt ttttcagggc accagtgggt ggacatgaat ggttccccac aggatttcaa

54661 cgtggctgtc agaatcactc ctctcaaata tgcccagatt tgctattgga ttaaaggaaa

54721 ctacctggat tgtagggagg ggtgacacag tgttccctcc tggcagcaat taagggtctt

54781 catgttctta ttttaggaga ggccaaattg ttttttgtca ttggcgtgca cacgtgtgtg

54841 tgtgtgtgtg tgtgtgtgta aggtgtctta taatctttta cctatttctt acaattgcaa

54901 gatgactggc tttactattt gaaaactggt ttgtgtatca tatcatatat catttaagca

54961 gtttgaaggc atacttttgc atagaaataa aaaaaatact gatttggggc aatgaggaat

55021 atttgacaat taagttaatc ttcacgtttt tgcaaacttt gatttttatt tcatctgaac

55081 ttgtttcaaa gatttatatt aaatatttgg catacaagag atatgaattc ttatatgtgt

55141 gcatgtgtgt tttcttctga gattcatctt ggtggtgggt ttttttgttt ttttaattca

55201 gtgcctgatc tttaatgctt ccataaggca gtgttcccat ttaggaactt tgacagcatt

55261 tgttaggcag aatattttgg atttggaggc atttgcatgg tagtctttga acagtaaaat

55321 gatgtgttga ctatactgat acacatatta aactatacct tatagtaaac cagtatccca

55381 agctgctttt agttccaaaa atagtttctt ttccaaaggt tgttgctcta ctttgtagga

55441 agtctttgca tatggccctc ccaactttaa agtcatacca gagtggccaa gagtgtttat

55501 cccaaccctt ccatttaaca ggatttcact cacatttctR gaactagcta tttttcagaa

55561 gacaataatc agggcttaat tagaacaggc tgtatttcct cccagcaaac agttgtggcc

55621 acactaaaaa caatcatagc attttacccc tggattataR cacatctcat gttttatcat

55681 ttggatggag taatttaaaa tgaattaaat tccagagaac aatggaagca ttgcctggca

55741 gatgtcacaa cagaataacc acttgtttgg agcctggcac agtcctccag cctgatcaaa

55801 aattattctg catagttttc agtgtgcttt ctgggagcta tgtacttctt caatttggaa

55861 acttttctct ctcatttata gtgaaaatac ttggaagtta ctttaagaaa accagtgtgg

55921 cctttttccc tctagcttta aaagggccgc ttttgctgga atgctctagg ttatagataa

55981 acaattaggt ataatagcaa aaatgaaaat tggaagaatg caaaatggat cagaatcatg

56041 ccttccaata aaggccttta cacatgtttt atcaatatga ttatcaaatc acagcatata

56101 cagaaaagac ttggacttat tgtatgtttt tattttatgg ctctcggcct aagcacttct

56161 ttctaaatgt atcggagaaa aaatcaaatg gactacaagc acgtgtttgc tgtgcttgca

56221 ccccaggtaa acctgcattg tagcaatttg taaggatatt cagatggagc actgtcactt

56281 agacattctc tgggggattt tctgcttgtc tttcttgagc tttttggaag gataattctg

56341 ataaggcact caagaaacgt acaaccacag tgctttcttc aaatcatatg agaaatacta

56401 tgcatagcaa ggagatgcag agccgccagg aaaattctga gttccagcac aattttcttt

56461 ggaatctaac aggaatctag cctgaggaag aagggaggtc tccatttcta tgtctggtat

56521 ttgggggttt tgtttgtttt tgctttagct tggtgaaaaa aagttcactg aacaccaaga

56581 ccagaatgga tttttttaaa aaaatagatg ttccttttgt gaagcacctt gattccttga

56641 ttttgatttt ttgcaaagtt agacaatggc acaaagtcaa aatgaaatca atgtttagtt

56701 cacaagtaga tgtaatttac taaagaatga tacacccata tgctatatac agcttaactc

56761 acagaactgt aaaagaaaat tataaaataa ttcaacatgt ccatcttttt agtgataata

56821 aaagaaagca tggtattaaa ctatcataga agtagacaga aaaagaaaaa aggactcatg

56881 gcattattaa tataattagt gctttacatg tgttagttat acatattaga agcatatttg

56941 cctagtaagg ctagtagaac cacatttccc aaagtgtgct ccttaaacac tcatgcctta

57001 tgattttcta ccaaaagtaa aaagggttgt attaagtcag aggaagatgc ctctccattt

57061 tccctctctt tatcagaggt tcacatgcct gtctgcacat taaaagctct gggaagacct

57121 gttgtaaagg gacaagttga ggttgtaaaa tctgcattta aataaacatc tttgatcMca

57181 aaacccttgt tttctcatat aatgcctata agcaatctgg tgttctacta aatacattct

57241 ggggatctct gtaacagcct tttggttgag gtggtaatgt agaaagaatg atgagtccga 57301 gtggggtcag gtgtctgtgc ctttagggtt taaccagacc ctataaccag gatttggaaa

57361 tcttcacagc gtgaaattag aagtaataaa tttgaaaatt atctgtcgct gagaatcaga

57421 agtttgtggc agaactgggg acacatgttt tacatagact ttactccaaa ttttgaattt

57481 tgaaaaggag atagtgtttt taaaaggtgg gaaaatagcc ttaaaggggt aaagaaatag

57541 gagcagagtt gtatgtgtaa tctttctttt tactgttttt ggaccaaaaa gggattgaaa

57601 taccaaggtc atgctcccaa ttccctgttc tttgtgtagc tcagtctacc tgcttgggga

57661 gatgggaagt acctggtgat gcctggatca tgtattcaag gaatcactct ttctctaaca

57721 aaccccacag gaggtcttta atgcagaact tgttaagaat gactaagcct gccctggaat

57781 gatgactcta ggctgctgtc tgctaactga agggtaaatg gcagccatcc agtgagtcca

57841 gaggaattct gacagtgatc cccaacactc actgagggct tccttcttac tttgcctggg

57901 ttctgctgct gttcatgtct gcactttttc tttgttcttg tcatgaacca gctcaggtat 57961 gccttgaagt tgcctctgac cattgatttc tatggatgtt tgataaggca gccatttcat 58021 ttatcattca gaatgggatt cttttgagaa tgctatgact aatgaagctg gggcagcagg 58081 tgtaagccag gtatgtcttg gccaacaagc atgtttggtc acttaattat taacctttca 58141 aagctctgta tagcgtgcag actggcagcc atccttgcta atctaggaac aaaggtgggg 58201 ctgcagctcc ctgcgtttct cctctctggg cttccattgt gattcctgtg ataccttctt 58261 tgcctggctc agcattctga gggcctccaa taggggaagg gcatttaaaa atccttttga 58321 tggggtgggg tcatcgtaca tacatggcag acatgaggcc atttctgggc gatcaacaac 58381 acatctgttt ttagtctggg gttccccccg gaggaggaaa taaaccagct tccagaacaa 58441 gagtaaacag gggttggccg ggcatggtgg ctcatgtctg taatcctagc actttgggag 58501 gctgaggcag gtggatcact tgaggtgagg agctccagac cagccctgct aacatgctga 58561 aaccccgtca ctactaaaaa tacaaaaatt ggccgggcat ggtggcgcat gcctgtaatc

58621 ccagctgcta gggaagctaa ggcaggagaa tcgcttgaaa ctaggagtcg gagattgcaa 58681 tgagccaaaa ttatgccact gcactccagc ctaggcaaca gagtgagact ctgtctcaaa 58741 aaaaaaaaaa aaaagaaaaa gaaaaagaaa aaagaaaggg taaacaggat tgagagctga 58801 gatagcagcc tggtatggga agatgatggc 'cttggagttg ggcagactga ttccacagtt 58861 gtctagttcc ttatggcaaa taaatcccaa tgcattgtgg tttaaaattt aaaccctcct 58921 atatgattta aagatcctcc ctcttctggg ttccagcttc tcagtgggct catttgaagc 58981 tgaggaagag agaaaggaga caggcatatt tatctgactc attgcagtga tgttctctct 59041 tcattgcttg ctgcttctca gataacacca gctcttctac cctccttagc ccttaactat 59101 ggtgatataa ccctctgtct cctgcgcacc tttatctaac agatagctgt ctcaagtaca 59161 cagccagcaa gatgcttcaa gcccagtcat cttgtttcct atttgcataa cccacaagaa 59221 actcataggc ttgctatacc tgtgtgttag tggcttattg agaatttggg agggaatatg 59281 tttgagcctc aacaaactga agtgcaaggg cccctggcag tatcaaattt gttctgttta 59341 agagacagat ggggaagagt tcaaaaagat agattccagc cagctcatat agaaattaag 59401 ga'ttctgtca aggtcttttt aattcatctt acttgctggg ggatacagtc aaaggacttt 59461 aagtaggagc cctggtgggg cctaatcagg accgacttat ccatgaaggg acagtaggca 59521 cagtgtctag ggcccacagc agtttcagag atcacacaga aatatttatt ttaaaatcag 59581 aagaagaaag ttaattttta agcctaataa aatgtgttaa tataatgtta atatatttat 59641 attaacagcc ataaaatata atttttaata ttttttaatg gagaaggaga cttatgaagg 59701 caaaagtgct tagggcccac aaaaatcaaa atgcagccct gaaactcatt catatttgac 59761 aatatctctt tggatgctaa atggagaatg gattttaggc agtggcaatg ggaaaactag 59821 taatccaggt aagaaatggc agtgactttg actttggaag tagaggatat tgaatagtgg 59881 tcatatctgg aagagtatat atttgaaagt agagccaaca tgaataggtg tggtaaagga 59941 ggaatcaaga atgactgctt ggcttggggc ctgagcatcc acagagattc caggtgccat 60001 ttgctgagat gggaaagact aaaggaagag aattagattc tgctgtggaa atgaaaaccg 60061 agaattcctg tgtcagtcat gttaggtttc aactgtctag cggacaccca aatgccaatg 60121 tcaaatgaac tataggatct ctgattgtga agctcagtag aaatatctca aatgcacttg 60181 tagatgatat ttaaaccaca gagaaataat atcatctggg gagagaatga ggcttgagaa 60241 gagaagaggg ctgaggacag agtcccagtc caccaacatt tagatgttgg gttcagtaga 60301 agagaaggag gaagaggagg aggaggagga ggcagtaagg aaRctggtaa gaagccacca 60361 ataaggttaa ggacaacaag gaaaatgtgg cctcaaagaa aScaagagaa aaaagttgga 60421 agccaggttg aggaagtgag agacaaaggg tgggacaaga tcagattgtg cttcaggtta 60481 tgtttagaaa tgtccctctg gctatggtgg gaaagacggg gtggaaggca ggagaccaga 60541 gaggagtctg tctagtcctc caagccYcag ctgttttcat gacaagcaga accttgcctt 60601 gtgtgtctct gtgcacccac catgcaagca tggggcactg tgcaccaggt atgcttatca 60661 tgcctgtgaa tgagggattg attaactgaa tcctccaggg acacttggga cagctctgcc 60721 cacaagaaga gcaagaaccc aggcatcaat ggggtggtgc aRacatgggc tcagggaggc 60781 cctctgccat cccctcctgc ctggaccaat gttttctgag aggcagaaag tgcagggtga 60841 ctcttcactg tggtatttgt ctatgtgtgt atcaagtgtg taaaaatact gtgctctctt 60901 agtcttgatt tatcactgcc ccttgtcttc gggctattaa aaggactaag gccctgtctt 60961 ccataaagag caagaacagc tttgagaagc gtcaagttcc aatccagtga agaaagactg 61021 aagtgtttgc cttggagaga atgaggagag tctcaggaaa tgaaataaac agaacaaggg 61081 gctagaatcc aagcagcagc cgtgggaaca gcagccagtt cttgccatcc aatgagatgt 61141 cttctcagga tggccttccc tggccatctt ctctgaaatt caatgcccct cagccccttc 61201 ctcggggagt tcttattgcc cttccctgtt ttattgtcct gctctgcact tatcactaac 61261 actgttatat ttatgtattt gtcctctgcc actagaatgt aatttcatga ggacagaggt 61321 ttttatctgt tgtgtcccca caattagaac agtgcctggc atgtaggttc tcaataaata 61381 atgttattca aatggctgat tgaacgaatg atcccagatg gtttatataa cccagaacat 61441 gatgacttag ggttatgtga gcttggatat ttcttgggtc caaacacatc ccagaataaa 61501 actcttgtgg tgttttgtat gtattctgtt ctattctagc atgtgttaca ttgctgttgt 61561 tatttatgtg tctgcctctt ctacaagact atgagccttg caagagcagg ggctgagttc 61621 tgttcttctg tgtcttccct tatctatccc atggtctagc acaggaaata tttgtgagaa 61681 agtgagtgtc tgtctgtctg tcatgactta gcctgtcatg acatagatcc tctcccacat 61741 ctcacaggca acaagctaga gttctgtgct atccatcacc tcctctccag ctcccctgcc 61801 actgccctga tttcaccttg ttgtttctcc tttaactatg acagcagatt ccaaactgga 61861 ttctgagcct cccagctcgc ccacacctgc ccaagacatg ttctgaagca aagacctgat 61921 caggcccctc ccctatgttt cctattgact agatgctggt tactagagaa gtttagtttt 61981 cttagccatg aatccatgac caatccaata tagtgatcag atttatcccc cattgcttcc 62041 cagagtcaca taacctgtcg tctagccaag ttgtaccaaa cacatccgtg ttttcaacct 62101 tctgtcattg ctcaagctct cctaccctcc agctaggttg cccttcctcc atctcttcaa 62161 ttagtcaatc attcagttat tcattcagca aatgtcctca agcccacctc ggtgccagtc 62221 actgtgttca cgctggggct gcagagatga ctgagataca tccctgtgct cagggtgttc 62281 atgcgtcttc tccttttgag gtcactgtag tcatgactct tgctctacct cccagagtga 62341 tgaggctcag taactaccct ctccacaaaa tatcttggcc tcagtacaat ggaattgcca 62401 ctttgtaaat tgaatgagtt gagtgcttcc cctacatttt aataagtctt tgagttaccg 62461 tcctgcctga ttattacatt tcctttcttg gatttattaa aacttgctcc acccccagtt 62521 ccctgatgga aaatgccatg tttggtaaac taacatagcY cccagcatga ctaatatcct 62581 ctgtggataa ggcattctgg gacataagga cactgttttt ttaaagtgac aggttttact 62641 actccaggat gatttccaga ccagctgaac acagcgttgg aatagaaatg ccaccacttt 62701 gtctttctac tttcacagaa aagatgtgtt ggttgagtat aacataatat caggaagaat 62761 tcattcaatt ccttcattat atctttaccg atcagcctct ttatgctttg ttttgttctt 62821 caagctgttt agtgtcccaa attctcttca ctttgtctga ggtcttgaaa attgtaaaat 62881 cctatgaaga ttcatctgca gaaaaagttt aacttgaaaa tctaattatt tataagacYM 62941 acttttgtga aagaataaaa catgatcatg cttgagtcta aaactctgga catttatagt 63001 tgcgatcaga tttatttcca ttctatattt tttcaaatgg cctatttttg cttgaaaata 63061 tggtttttga ggggcaagaa agcctttttt tgtgattttt tttattgcct tctaactgtg 63121 ggcttctgtt tccctcatgc tttctatttc atgtatagta tattttggat catgtttttc 63181 ctgactctgg aacttcctat aactttttat atggtgttcc ttttagatac tgttttaaaa 63241 actctttctt ttgaaatgtg tcaatctgtc cagagaatta agttaatgat gtggctattt 63301 ttaaactctt tagatagcta tggttgaaaa gacaaaaaac aaagtgagca attctgtgac 63361 tgcagataga acttttctaa atggctggct ggcatttttg agacaaaact ctatactttt 63421 attgaaatac ctctatttct ggctcatgga ttgtcaccgt attctagaag taagacaaag 63481 agccttgtct ggtggacctg aacaccaatt agagtttctt ttcaagagta tcactattca 63541 gctctcctgt ttgccactgg ccagttgact ttttatagcc agtgaaaatc catccaagaa 63601 tcctgcagtt tcttcatgaa tttgttcttg taatgaattt acgttgtgtt caggcaagta 63661 tcagatcatt catttatgaa accaacaagc atgtattgag tacctgtaat gtgccagaca 63721 cttttatgaa tgatttacat atattaatta attcacttcc cactacaaac ctatgaagta 63781 ggcattgatt ttgtatccat gtcagagagg ggctaattga agcaaggtaa cttgccaaaa 63841 acacacagct agaaatggga ttcatatctt agcagtctgc cttgggagtt catgctctta 63901 ttctactaat agcaaggtgc cataagacta ccgtgagtgg agcaactaac catgcctcca 63961 gattgggagt caggagcctc agggaaggca aattcagaac aagagttgtt tgatccttga 64021 tgaagaggct taatcgttga. tttgatcctt gttagcaact gattagcaca taccaaatta 64081 cctgcagaga agatacacca gaaaaaaata tgtgcacata tctgcaaagc tgtattacat 64141 acctaaaaac tttgtatcat cagtacaagt ataaaacaaa tcatgtgtga tttgattcat 64201 ttatacatgc taaccaaata ttttcagatt tcctttatgc tgtgccacat catatgtatc 64261 attaattgaa atctattttg aatggccaac attcagaagt ttctcgagtg cctggggtgg 64321 gaatctaaat ttttaagaca cactattgtt tcaaccattg tttttcctta taacatgatt 64381 ctgatcaatt tgtatttagt aagtgtttcc gaccatttag aaagaccttt cctttctaaa 64441 tcaacacgta acttgaaaaa ataaatcaaa attttgaaat atcaccttgt tctgtagatt 64501 cagactaaac gatctcagat ttcttcatgt gttggaaaat gtacttaaaa aaaatctttc 64561 cccgaggcat cttctttgcc aactggactg acttttgctc attcttggat tgccccctag 64621 tggtttattt aacttatgac tatttcccag atgctcatcg gcaactcgtg gtttctttga 64681 atttgttttt agtttgatct tttccacacc ttctcccatt tgcagagagg ggcttccaaa 64741 gacagtgtct ttgaatgagg gtgagcaaqg tgcaaagtgg cacaaacgct tagtgttaat 64801 caatacatgc cattaatgat ggtggtgaaa tccttctttc aagtttgttc tctttttttc 64861 tttgtgctgt ttttaacttt gccaactcct tactttcttc cctctgttaa catcctactg 64921 gagtggtgcc aggtaatctg gtggcacagg atgacttaca ggcaatgctg tgtcttgaaa 64981 atgccaatta ggaatgctga atgctgctgg gcgggagtcc catgctctca cccatataac 65041 aagtcagcac tccataggcc tcagtcagac ccagacttct tggctccttt tgggtagcta 65101 aggctatgac tcgctggcct agacacttaa gcatcatcca aatagcgaga aaaacctttg 65161 agtttctgta gaaagccagc gagagaccca gacagcatca cagacctgac actctgcaga 65221 actctgggtc caggccatct gcaccaatta gaccagaacc aagaaacgca gtgcaagatg 65281 cattattaat tcaaaacttt tttcaataag aaaaaagcca attattggct ccattttttt 65341 ttagagagag aacacctaca ctgctatata taatttatta acttagttta gtctctcaat 65401 atttagcaag tttgtttaaa aattaccatt cccattggtt tatagtgaca tgaatataaa 65461 cccataattt caaagtcagc attcctttca ctgtgaacat aaggcttctt aagagatagt 65521 gggggttggg gaacagtaat gactgtggct ggtgggcact gttcaaagcc aaaaagactg 65581 gcaggtttgg aaaggcatac actgtgtata gacactctct cagtatacta ctgttcccca 65641 cacttttgct gtacattctt gtctcaaaat atggtataaa ttattccctt aaatttgaaa 65701 aaacaattaa gatgaataca ttttcatctt catttcacaa taactctttt aaatataaaa 65761 agttcctcat gtttgttaaa tctgttcaaa agttgcattt aagtactttc ttcacaacat 65821 gtacaatgtt ttcatcctta gtgcctcatt acaatcagtt tggcaataag acctccagtg 65881 ctttatcaaa aatggcattc aatagattat aagattgata aatctgcatt tgaatcagtc 65941 ttaccacaat gaattataac aaagtccaaa aaatgtataa ctattcatca acacccttgg 66001 aacctatgaa ttattgcaaa taatctccca cgtgcatgta attcaaacat aaactttgtg 66061 gggagggggt gtaaaataaa tactacagta tttcttcaat tttatttaat gctgcctagc 66121 tggttaaatg aaagattaat tactaacagg aagagtcaaa attttaagga ctgttttcta 66181 agaaggacaa ttttgcaaaa caaagataag caagagccta tgcaaataca ttttcttgta 66241 gtataatgta attgctaata tgaggtataa tctgtaagca attaatacaa atataaataa 66301 gtataagcca ccactaactc acagtctcat gaaaagcttc tcagctaaag tagtttgagg 66361 ataaggttaa gggaaatgag gagtggacag ggcaggtttc cagtgggaac atcatttatg 66421 tgccttatca ttatcatcat cctgtatgta ccagtccatt gttgcagaaa ggtaaatcct 66481 ttccaagtat gttatacttt atgtagcaca gtaaaattat ttaagtatta ctaacgcttt 66541 atttgcgttt gtatttagat atacacataa ttatatatgc atatcaaaaa ctataaacag 66601 aattttaaaa cactttatct catttgagga aagttaacag gtaagacaaa tctatgtact 66661 atagaatttt tgaggatatc taaactcagg gtgaaacaaa gaaaaacatt tctacctctt 66721 tagtaaaggg cttgtgtgaa acctcaagct ctcgctcaat tttttttata gatgggtatg 66781 tttgatgagg attgtgatcc aatgattgtt tagcagcaat tttacccaac tgtaaattct 66841 tttattaaca ggcattataa acagatagta ctaatcttat tctaaaacca tgagtgccac 66901 actggtgaat atacagctta tgaataactt aaaaagtatt tcccatttta aaaggcaaac 66961 ccagcataca aaaacttata ctaaatgaag aagctataat atggatacat gattgatgtg 67021 tctaaaatga tatatacagt acataattaa tgttaattat gtgatctgta catttttcca 67081 tgattccctt catgcttcac tttccccaga aactgaaacc tgtacttcct cttctaaaat 67141 tggtacaatg aggttatccc tggacatcaa attatatttc atctaattca tcacaaattt 67201 agtaatccga tgacacaaaa atgtttcctt ttcatattca tcaaatatct accaatgatg 67261 aaaataaaca tgtgaaaata ttctgtaact cctaaggtat agtgatccta gttttgctac 67321 ggattacttc tttatgctaa ccctgctggg aaaacattga ttgctcttca gaagacatgc 67381 agcaccatca agtatgtgtc tggtataggc tatagcagga cactctttca gagctttatg 67441 agctgcacaa agaaaaatcc attgttcagt tgctgtcatt tgagtgcaag tatctggatg 67501 gcattcactc tgaagtttga caacaagtcc gtttagctca agacagaatt cccttaaatg 67561 ttcatacttc cataactttc atcttggcct tcagctggtt caagaatttt gtcaatattg 67621 gagcaatctg ctcttatgtt ctgttgaata tactgttgaa cagctagtgt actgtctatt 67681 tcttcaaagt gttcgtcagg ccaattataa aaatcctgtg cccagcccgt tccgcctcag 67741 cacgctgccc cctccgccat gaccatagtg tcagcgtctg ggcctattgg ctcgatttaa 67801 taagtaagag taccaataat tttttagaag taaaatggat gtattaaagg attttaaaga 67861 aaaagcactt gcttttatct gaattttaaa aggagaattg acattacaga tgaaataaag 67921 atgaatacag aagagaagat cctactttaa atgcaaaata atatctataa aatgggacta 67981 gtaatttctt cctagagagc ttgtgataac tagagataat gaatataaag tgaccagtga • 68041 attatcaagc acataatagg ggttcattta tttattcgtt catttggcaa atatttattg 68101 agcacctact atgcaaggca tagtaggtaa aactgaaaaa cgtgtctttg tgaagtttac 68161 gtggtaattt tccatcccat atgccaaaga gataacaggg gaggaatgac caccatcttt 68221 tagagacttg tagtatcatt taggagatga aatgttatgt tttatgtggc tgtagaaagc 68281 aaaactagag ccaggcatgg tggctcacgc ctgtaatacc aacactttgg gaggctgagg 68341 cgggagaatg gcttgagctc aggagtttga gaccagcctg ggccacatag tgagacctcg 68401 tctcaacaca acatcgaaaa attagctggg tgcagtgaag tgtgcctata gtcccagcta 68461 atctggaggc tgaggtggga ggatagcttg agcctgggag gtcgagactg cagtgagctg 68521 tgatcacgcc actgcacttc agcctgggcg acaagagtgt gaacctgact aaaaaaaaaa 68581 aaaaaaaaaa tgcagaacta ggaccagtgg atgatctttc aagggtggtg gttttcataa 68641 tgaaaggaaa accctgttta caaccaggac tgtccaggaa tgggatgggg ccacctctgg 68701 gagcagagag acatgggctg gaggtgattc tgttagtgga agtattttgt agagaatttg 68761 agaccttgta tcaaggatct ttgcagcgtg ggcaaggagg gaatacaaaa tcggtgtttc 68821 cttctgcctc ttaattccaa gatgctggaa ctggggtggg aagccaagcc attgaccaga 68881 accagggcta caactcgggg gtgagtgtgg gagtttaaat gcaggatcca cactggttac 68941 agctgaactg gagccacaga ttcctgtcac tttctgcctc cagggatcaa gtaccatggg 69001 tctcgacctg accagcctga aggtttggga ggccccgtca ggggatgggg gcaagttact 69061 ttccctaaaa gaatgaagag gctacatctg gtgaccagac acaaacatgg aggcagaggg 69121 taataaggat gatacataca atttattcag ttcctatttc ttttacttta gtattcctaa 69181 tctgtaaaag catcataaaa aaaaatgtat gattaatctc attttacaga tgaagagact

69241 gacggtccga gatgtagaat agctaaccta atttagtgta aagccaggac tttgaacttg

69301 ctgtctctgt gtttcatcta cttcagatgg ctccctaatg agtagaatga gacctgtgtg

69361 ccaaccctgg cctagtcctc atgcccccac aactgtgaag cgagagggct caacagtttc

69421 gaattcaatt caaccaccac ctcctgaata ccaactaggt tccaggacct ggctagaagc

69481 agagacacca ggacagaaaa gacagtgttc tgctttcatg gagttcacag aagagtcgag

69541 gaggtaagtt catatcagat tatcacaaag cagtgtgctt aatggtgctt aaatcttttc

69601 atgtttccac attttctaat gcattttaac ggagcaaagc aatgtcacat tggtttcatc

69661 aagaattcag agcaggccgg gcgcggtggc tcacgcctgt aatcccagca ttttgggagg

69721 ccgaggcggg cggatcacga ggtcaggaga tcgagaccat cctggctaac acggtgaaac

69781 cccgtctcta ctaaaaatac aaaaaattag ccgggcgtgg tagcgggcgc ctgtagtccc

69841 agctactcgg gaggctgagg caggagaatg gcgtgaaccc gggaggtgga gcttgcagtg

69901 agccgagatc gcgccactgc agtccggcct gggcgacaga gcgagactcc gtctcaaaaa

69961 aaaaaaaaaa aaaaaaaaaa agaattcaga gcaaggggct ttggtgaaga gaagtcaaag

70021 ccaaaagagg gctctgccSt ttagaagaag gggaatcatt cagcctgggc aacatagtga

70081 aatcccgtct gtacaaaaac ttcaaaaatt agccgggcat ggccccgtat gcctgtggtt

70141 ccacctactt gggaggctga ggtgggagga tcgcttgagc ctgggaggtg gagattgcag

70201 tgagccaaga tcacaacact gcacttactc cattctgggc aaaagagtga gatcctgtgt

70261 caaaaataaa aataaaaata aaaataaaat aaaataaaat aaaataaaat aaaataaaat

70321 aaataaaata aaaaaacaaa atggaggaaa gtaagaacag tggggtgagg cctttgaact

70381 ctgaaattat gatggaaccc agtcttttta tctttttttt tttaaatttt attttattat

70441 tagtatactt taagttttag ggtacatgtg cacaatgtgc aggttagtta catatgtata

70501 catgtgccat gctggtgtgc tgcacccatt aactcatcat ttagcattag gtatatctcc

70561 taaagctatc cctcccccct ccccccaccc cacaacagtc cccagagtgt gatgttcccc

70621 ttcctgtgtc catgtgttct cattgttcaa ttcccaccta tgagtgagaa tatgcagtgt

70681 ttgctttttt gttcttggga tagtttactg agaatgatga tttccaattt tatccatgtc

70741 cctacaaagg acatgaactc atcatttttt atggctgcat agtattccat gatgtatatg

70801 tgccacattt tcttaatcta gtctgtcatt gttggacatt tggattggtt ccaagtcttt

70861 gctattgtga atagtgccac aataaacata cctgtgtatg tgtctttata gcagcatgat

70921 ttatagtcct ttgggtacat acccagtaat gggatggctg ggtcaaatgg tatttctagt

70981 tctagatccc tgaggaatcg ccacactgtc ttccacaatg gttgaactag tttacagtcc

71041 caccaacagt gtaaaagtgt tcctatttct ccacatcctc tccagcacct gttgtttcct

71101 gactttttaa tgattgccat tctaactggt gtgagatggt atctcattgt ggttttgatt

71161 tgcatttctc tgatggccag tgatggtgag cattttttca tgtgtctttt ggctgcataa

71221 atgtcttctt ttgagaagtg tctgttcatg tccttggccc actttttgat ggggttgttt

71281 gtttttttct tgtaaatttg tttgagttct ttgtagattc cggatattag ccctttgtca

71341 gatgagtagg ttgtgaaaat tttctcccat tttgtaggtt tcctgttcac tctgatggta

71401 gcttcttttg ctgtgcagaa gctctttagt ttaattagat cccatttgtc aattttgtct

71461 tttgttgcca ctgcttttgg tgttttagac atgaagtcct tgcccatgcc tatgtcctga

71521 atggtaatgc ctaggttttc ttctagggtt tttatggttt taggtctaac gtttaagtct

71581 ttaatccatc ttgaattgat ttttgtataa ggtgtaagga agggatccag tttcagcttt

71641 ctacatatga ctagccagtt ttcccagcac catttattaa atagggaatc ctttccccat

71701 tgcttgtttt tgtcaggttt gtcaaagatc agatagttgt agatatgcgg cgttatttct

71761 gagggctctg ttctgttcca ttgatctata tctctgtttt ggtaccagta ccatgctgtt

71821 ttggttactg tagccttgta gtatagtttg aagtcaggta gggtgatgcc tccagctttg

71881 ttcttttggc ttaggattga cttggcaatg cgggatcttt ttggttccat atgaacttta

71941 aagtagtttt ttccaattct gtgaagaaag tcattggtag cttgatgggg atggcattga

72001 atctataaat taccttgggc cgtatggcca ttttcacgat attgattctt cctacccatg *

72061 agcatggaat gttcttccat ttgtttgtat cctcttttat ttccttgagc agtggtttgt

72121 agttctcctt gaagaggtcc ttcacgtccc ttgtaagttg gattcctagg tattttattc

72181 tctttgaagc aattgtgaat gggagttcac tcatgagttc actcatgatt tggctctctg

72241 tttgtctgtt atttgtgtat aagaatgctt gtgatttttg tacattgatt ttgtatcctg

72301 agactttgct gaagttgctt atcagcttaa ggagattttg cgctgagacg atggggtttt

72361 ctagatatac aatcatgtca tctgcaaaca gggacaattt gacttcttct tttcctaatt

72421 gaataccctt tatttccttc tcctgcctaa ttgccctggc cagaacttcc aacactatgt

72481 tgaataggag tggtgagaga gggcatccct gtcttgtgcc agttttcaaa gggaatgctt

72541 ccaatttctg cccattcagt atgatattgg ctgtgggttt gtcatagata gctcttatta

72601 ttttgagata cgtcccatca atacctaatt tattgagagt ttttagcatg aagcattgtt

72661 gaattttgtc aaaggccttt tctgcatcta ttgagataat catgtgattt ttgtctttgg

72721 ttctgtttat atgctggatt acatttattg atttgcgtat actgaacgag ccttgcatcc

72781 cagggatgaa gcccacttga tcatggtgga taagcttttt gatgtgctgc tggatttggt

72841 ttgccagtat tttattgagg atttttgcat cgatgttcat caaggatatt ggtctaaaat

72901 tctctttttt ggttgtgtct ctgcccagct ttggtatcag gatgatgctg gcctcataaa

72961 atgagttagg gaggattccc tctttttcta ttgattggaa tagtttcaga aggaatggta

73021 ccagttcctc cttgtacctc tggtagaatt cggctgtgaa tccatctggt cctggactca

73081 ttttcgttgg taagctactg attattgcca caatttcaga gcctgttatt ggtctataca 73141 gagattcaac ttcttcctgg tttagtcttg ggagggtgta tgcatcgagg aatttatcca

73201 tttcttccag attttctagt ttatttgcgt agagatgttt gtagtattct ctgatggtag

73261 tttgtatttc tgtgggatct gtggtgatat ctcctttatc attttttatt gcctctattt

73321 gattcttctc tcttttcttc tttattagtc ttgctagcag tctatcaatt ttgttgatcc

73381 tttcaaaaaa ccagctgctg gattcattaa ttttttgaag ggatttttgt gtctctattt

73441 ccttcaattc tgctctgatt ttagttattt cttgccttct gctagctttt gaatgtgttt

73501 gctcttcctt ttctagttct tttaattgtg atgttcgggt gtcaattttg gatctttcct

73561 gctttctctt gtgggpattt agtgctataa atttccctct acacactgct ttgaatgtgt

73621 cccagagatt ctggtatgtt gtgtctttgt tctcgttggt ttcaaagaac aactttattt

73681 ctgccttcat ttcgttatgt acccagtagt cattcaggag caggttgttc agtttccatg

73741 tagttgagtg gttttgagag agtttcttaa tcctcagttc tagtttgatt gcactgtggt

73801 ctgagagaca gtttgtaata atgtctgatc ttttacattt gctgaggaga gctttacttc

73861 caactatgtg accaattttg gaataggtgt ggtgtggtgc tgagaaaaat gtatattctg

73921 ttgatttggg gtggagagtt ctgtagatgt ctattaggtc cacttggtgc agagctgagt

73981 tcaattcctg ggtatccttg ttaactttct gtctcattga tctgtctaat gttgacagtg

74041 gagtgttaaa gtctcccatt attattgtgt gggagtctaa gtctctttgt aggtcactca

74101 ggacttgctt tatgaatctg ggtgctcctg tattgggtgc atatatattt aggatagtta

74161 gctcttcttg ttgaattgat ccctttacta ttacgtaatg gccttctttg tctcttttga

74221 tttttgttgg tttaaagtct gttttatcag agactaggat tgcaacccct gccttttttt

74281 gttttccatt tgcttggtag atcttcctcc atccttttat tttgtgcctg tgtgtgtctc

74341 tgcacatgag atgggtttcc tgaatacagc acactggtgg gtcttgactc tttatccaat

74401 ttgccagtct gtgtctttta attggagcat ttagtccatt tacatttaaa gttaatattg

74461 ttatgtgtga atttgatcct gtcattatga tgttagctgg ttattttgct tgttagttga

74521 tgcagtttct ccctagcctc aatggtcttt acaatttggc atgattttgc agcggctggt

74581 accggttgtg cctttccatg tttagtgctt ccttcaggag ctcttttagg gcaggcttgg

74641 tggtgacaga atctctcggc atttgctcgt ctgtaaagta ttttatttct ccttcactta

74701 tgaagcttag tttggctgga tatgaaattc tgggttgaaa attcttttct ttaagagtgt

74761 tgaatattgg cccccactct cttctggctt gtagagtttc tgccgagaga tccgctgtta

74821 gtctgatggg cttccgtttg tgggtaaccc aacctttctc tctggctgcc cttaacattt

74881 tttccttcat ttcaactttg gtgaatctga caattatgtg tcttggagtt gctcttctcg

74941 aggagtatct ttgtggcgtt ctctgtattt cctgaatctg aatgttggcc tgccttgcta

75001 tattgggaag ttgtcctgga taatgacctg cagagtattt tccaacttgg ttccattctc

75061 cccgtcactt tcaggtacac cagtcagatg tagatttggt cttttcacat agtcccatat

75121 ttcttggagg ctttgttcgt ttctttttat tcttttttct ctaaacttcc cttctcgctt

75181 catttcattc atttcatctt ccatcactga tatcctttct tcaagttgat cacatcggct

75241 cctgaggctt ctgcattctt catgtagttc tcgagctttg gctttcagct ccgtcagctc

75301 ctttaagcac ttctctgtat tggttattct agttatacat tcgtctaaat ttttttcaaa

75361 gttttcaact tctttgcctt tggtttgaat ttcctcctgt agctcatagt ttgattgtct

75421 gaagccttct ctcaactcgt caaagtcatt ctctgtccag ctttgttccg ttgctggtga

75481 gaagctgcgt tcctttggag gaggagaggt gctctgcttt ttagagtttc cagtttttct

75541 gctctgtttt ttccccatct ttgtggtttt atctactttt tgtctttgat gatggtgatg

75601 tacagatggg tttttggtgt ggatgtcctt tctgtttgtt agttttcctt ctaagagaca

75661 ggaccctcag ctgcaggtct gttggagttt gctagaggtc cactgcagac cctgtttgcc

75721 tgggtaccag cagcggtggc tgcagaacag gggattttcg tgaaccacga atgctgctgt

75781 ctgatcgttc ctctggaagt tttgtctcag aggagtactt ggccgtgtga ggtgtcagtc

75841 tgcccctact ggggggtgcc tcccagttag gctgctcggg tgtcaggggt cagggaccca

75901 cttgaggagg cagtctgccc gtcctcagat ctccagctgc gtgctgggag aaccactgct

75961 ctcttcaaag ctgtcagaca gggacattta agtctgcaga ggttactgct gtctttttgt

76021 ttgtctgtgc cctgccccca gaggtggagc ctacagaggc aggcaggcct ccttgagctg

76081 tggtgggctc cacccagctc gagcttccca gctgctttgt ttacctaagc aagcccgggc

76141 aatggtgggc gcccctcccc cagcctcact gccaccttgc agtttgatct cagactgctg

76201 tgctagcaat cagcgagact ccatgggcat aggaccctcc gagccaggtg cgggatataa

76261 tctccttgtg catcgttttt taagcctgtc ggaaaagcgc agtattaggg tgggagtgac

76321 ccgattttcc aggtgccatc tgtcacccct ttctttgact agaaaaggga actccctgac

76381 cctttgcgct tcccaagtga ggcagtgcct cgccctgctt cagctcgcac atggtgcact

76441 gcacccactg acctgtgccc actgtctggc actccctagt gaggtgaacc tggtacctca

76501 gatggaaatg cagaaatcac ccatcttctg tgtcgctcat gctgggagct gtagaccaga

76561 gctgttccta ttcggccatc ttggcttgac tctgtaatat cctatagaag tgttgctcct

76621 catatcacag gggctataca ccccgtaata ttattcgtaa tatcctaggg agacattact

76681 actaatatca cagaggtgta caccctttaa cattatttgt aatatcctag gaagatatta

76741 ctcctaatat ctcactgggt gtacaccctg tgatattatt catgatatcc tagggagatg

76801 ttcctcctaa tgtcatcagg ggtgtacacc ctgtgacatc atttgaaata ttctatgggg

76861 atgttacttt taaagtcaca gggggtttac aaactgtgat attatacata atgtgctaca

76921 cggatgttac tcctaatgtc acaggcgtgt acacccagtg atattatttg gaatatccta

76981 gggggatgtt tctcctaatg tcaacggggt ttacaacttg taatactatt cgtaatatcc

77041 taggcggatg ttattcctaa tgtcacagaa ggtgtacact ccgtgatatt attttttata 77101 tcctagcagg atgttattac taatgtcaca atgcttgtac accctgcgat attattcata

77161 atatcctaag ggaatattac tcctaatgtc atagcgggtt tacacctttt tgtattattc

77221 gtaatatcct aagggaatat tactcctaat gtcatagcgg gtttacacct ttttgtatta

77281 ttcgtaatat cctagaaagt tgttactcct catgtcacag ggtgtgtaca ccctgtgata

77341 ttttttgtaa tatcctagtg ggatgatact cctaatgtca tagcaggtgt accccctgtg

77401 aaattttttg taatagtttt gggggatgtt acttttaatg ttacacgtgg tatacacacc

77461 gtgatattat tcgtaatagc ctatagaaat gttactctta atatcaccgg ggctctacac

77521 cctgtaatat tattcataat atcctagggg aatgttacta ctaatgtcac agggggtgta

77581 cgccctgtga tatcattcct aatattctag gggatgttac tcctaatgtc acagggggtg

77641 tacacactgt gatgttattc ataatatcct aaaggtatgt tactaccaat gtcataatgc

77701 ttgtacacct tgtgatatta tttctaatat tctagagaga tgttactcct agtgtcgcag

77761 cgggtataca ccctgtcata ttatttgtaa tatcctatgc cagtgttcct cctaatgtca

77821 caggtgatgt gcaccttgtg atattattca caatattccg gaatgatgtt actcctcatg

77881 ttccagtgtg tgtacaccct gtgatattat tcgtaatatc ctagggggac cttactccta

77941 atgttcgaga tggtgtaact cccgtgatat tactcataat atccgaggta aatgttactc

78001 ctaatgtcac aggggatgta tgccatgtat gtacaccccc tgtgatattc ttcataatat

78061 tctatgggga tgttgttaat attactggtg gtgttcacca tgtgcgtaca cccccagtga

78121 tgtcattcat aatatcgtag ggagatataa ttcctaatat cacagtgggt gtaccacatg

78181 tgtgaacacc cttgatatta ttcataacat ccagggtaaa tatgacttct aatatcacag

78241 agggtgtaca cctggggata tttttcacaa tattttaggg aaatatggct tctaatatca

78301 cagtgggtgt actccatgtg tgtacactct gtgatagtat ttttcatatc ctagggagct

78361 attactctta atatcacagt gggtcttcac cctgtgatat tattcgtatt tgaccttgct

78421 gcctttttta acccacacta caaaaggaat ggaacagata ataaaataat gagattaaac

78481 tgttctgcca tgcaaccacc acaggaccct tttgatgtcc ctgtttctca gtctgtagat

78541 gaaggggttc agcatggggg tgatcaccgt gtacatcatt gaggccactg caccctttct

78601 gggggaagat gacacatctg aactcaggta ccccccaacg acttttccat aaaataagca

78661 aacaactgac aggggagacc cacaggtgga gaaggcttta tacttcccac ctgatgatga

78721 aacactcagc atggaggaaa caattttata gtaagagaaa atgatccgtg agataggaag

78781 aaaaccaaat atggcagcaa ggaaatacat gactatgtta ttggtgaagg tgtcacaaca

78841 cgcaaggtgt gggagttgag aagggtcaca gaagaaatta ggaatttcca catccttgat

78901 gcaggtcatt tgtaaggcaa tcaaattgtg cagctgggag tctaaaagac tgagaaaaaa

78961 aaaaacacaa aactaggaag ccacagaaac atgggttcat gatggctgaa taatatagag

79021 ggtgacagat ggctacaaac cggtcatagg ccctcacact caggagcatg tctttcttcc

79081 atgcctccaa aaacagcaaa gagagacatc tgagtcaggc agcctgcata ggagatgact

79141 ctgctgtgag attggatgtc cacaatcatc tKggggaccg tgttggaggt gaaaccgatg

79201 tcagccaagg acaggttgga gaggaagaag tacatggggg tgtggaggtg gaagtcagag

79261 ctgacggcca ggataatgag cagattctcc agcaccatga ctaggtacat gaacaggaac

79321 agcccagcga gggccagctg cagttttgga tcctctgaga gttctaggag gaggaatttt

79381 gaagcatctg ttagattctg tgggtctgta tagttcggac atgtatatat atatatatat

79441 ttactgttgc aagatttaat agagtgaaga cagagctccc atacaaaggg aggggatcca

79501 tagagggtag ccattgctgg ctcgaatgcc tgggtttata tccagatcat tttccctccc

79561 actgtgctct caggccatag atgattggct atttctttac ctcctgtttt tgcctaatta

79621 gcattttagt aagctctctt attggtcggg cgtgagctaa gttgcaagcc ccgtgtttaa

79681 aggtggatgc agtcaccttc ccacctaggc ttagggattc ttagttggcc taggaaatcc

79741 agctagtcct gtctctcagt cccccctctc aacaggaaaa cccaagtact gttggggagg

79801 ttggccgact gaccactcta actgcttctt gctgaattgg ggcatagtag gggttgtgca

79861 gttgagattt cctcgggagg ggtgccttcg atgtcattaa catcagagca tgtgctagca

79921 ggccggtcca ggggtccatg gtagatctta gtcatggact gcatctgggg ctccatttga

79981 agaacatttg tagttttaca gcttcgattc tggaagagac aaacttaaca aggaggttag

80041 agatacaggg attgaaatgt atggcctgca gtgcagggga ttatttcttt ggcacacttc

80101 acaggccctg accatctgct taatagtttt gaagaggcct ggtccagtaa ataagaattt

80161 ggccatctga tgggtgctat caatgcctaa gtgaaagatt tggtgaaggg ttttaagtaa

80221 ttttcattgg ttagctgcag gcaaaagtat ttttccttct tcggtggcta gtcatcctga

80281 ggggaggaaa ctatgtcctc ctgaggttcc ccattctatt tcttcttctg agtaccggga

80341 cttggttttc ccgaggggat tacccaaact aggggtcctt ctataagcat ttctaatgaa

80401 gcgtcctgcc ttgcggttct tttggcttca atatctgctt ggtgattccc ttctattttc

80461 ctttcctttc ctttcctttc ctttcctttc ctttcctttc ctttttcctt tcctttcctt

80521 tcctttcctt tcctttcctt tcctttcctt tcctttcctt tcctatgact ccggcagtgt

80581 aagactgcca cctctttagg ttgctgtaca gccaataata atttcctaat ggcttcctga

80641 tgtttgatag gtgttccctc ggaagttagg aattcccttt ctctccatat tgctgcatgg

80701 gcatggagga ctaggtaagc atacatagag tctgtatata tatttaccct ttttccttct

80761 cctaattcta gtgcccgagt aagggctatt agttctgcca gctgaacagt agttcctgga

80821 gtgaggggat tactttcaag tattccatta tcactgacca ctgcataccc cgcttttcga

80881 agtccttttc ctacaaagta acttccatca gtatacaagt tgaggtgggg atcagtcaag

80941 ggaacctcta aatggtcccc tcaagtggca taggtttgag caattacttg ttgacagtta

81001 tattctacct tttcttcatt gtctggaaga aatgtagctg ggttaagagt tgcacaagtg 81061 tgcagttgca gcactggcct ttcaagtaat agagcctgat atttaagtaa acagttgtct 81121 gacagccaca agtctccttt agcagtgagt atgcctttca catcatgaga tgtccacaca 81181 gtaagatctc ttccttgtat tattttaact gcttcagata ctaagactgc tactgccacc 81241 actacctgta aacaatgagg ccaacctttt gccgctacat caatttcctt actcaggtat 81301 gccatgggtt gcaagctcat cccttggacc tgtgtaagga ctcctagagc tattcctgtt 81361 ttttctgtga catataaaga aaagtcttgc cccgttggca agcttaacac tggggcttgg 81421 gttagggccc tctttagggc ctggaaagct gcttctgctt caggggtcca tcttactaaa 81481 tgggtattgg ctttttgagt ttccttaatt agtgtatata atggtctggc tatttcgtct 81541 tacctgggaa tccatattcg gcagaaacct gttatgccaa ggaaccctct tagttgcttt 81601 agggttttag gatgagatta agccagtata ggctggatac gttcctcact gagggccctg 81661 gtgcctttgg ataattttag ccctaagtac gtaacctcct gtgagcagag ctgagccttt 81721 ggtttggaaa ccttgtagcc acaggtagtg aggaaattta agagtgcttg ggtggcttga 81781 tggcacaagg tttctgaacg ggcagctaaa agtaaatcat ccacgtaccg aaggacaaga 81841 gtgtccaggt atgagaattg gctcaagttt tgggctaata cctggccaaa tagatggggg 81901 ctatccctga accctttcgg taaaacagtc caggtgagtt gagatgtggg gtttgaaggt 81961 tcttcaaagg caaacaagaa ttgagagtca ggatgtacag ggatgcagaa aaagtcatcc 82021 ttaaggccca ggactgtaaa ccactctgct tcctctggta tttgagaaag cagagtgtaa 82081 gggttaggta cagctgggta tagagggaca agggcctcat tgataatcct gagatcttgc 82141 actaacctcc actgtccgtt gggtttctgt actcctaaaa ttggagtatt gcaggggcta 82201 ttgcacggtt ttactaggcc ttgggctttt aggtccttaa caatcttttg gagtccttgt 82261 tgggccttgg ggtctaaggg gatactgcct ttggtaggga aaggaggcag aatcctttag 82321 tttgacttga acaggatggg tattctttgc tcatccatat tgtccttctg ttacacagac 82381 tt.caggatta attccttcct caagcaggga agaacaaatg ggtgttcctt ttcctatgtt 82441 caggtgtgta atagcccctg cttttgctag aatatctctc cctaacaagg gagtggggct 82501 ttcaggcata attagaaaag catgtgaaaa cagtaaagct ccctagtcac aacttagtgg 82561 ctgggagaag tatctagtga ctggctgtcc caggacccct cgaatagtga cagatctgga 82621 ggacagttgt ccaggacagg agagtaagac tgagaaggcc gtgccagtgt ccaggagaca 82681 attaacctcc tggctgtcaa tggtcaagca tacccagggc tctgtgaggg tgatggcatg 82741 gactggcact tgccccgggc accctcagag tttggacata ttttgagtag aaaagaggat 82801 tgaaaaatag aaaacaagta aaccaacWcc cagaactgtg tctgcatttt ggatataagc 82861 aattcacaag taatgtKttc agatttcaga gcaatccaca ctcagcaata ttgtgcagtt 82921 ctgacaaact caattttttt ataattcttt tattgagttt tgtgttattc acttcttgct 82981 gtacacacct gccttagaga cactagattc aagaatgttc ^caagaaccag atcatcatat 83041 ataacaaatt cataattgct agaaaataca gcctatcttt tccaaagaaa aatatgtaat 83101 aaaatcattc tctttgcttt aagaaaaagt ttatcctaat taaaagaaat taagaactca 83161 aatgtattat tttattctaa tagattgcca caagttccct tgatttagaa catttataaa 83221 cactgtgtaa cagctgagac caggtcatct ggaaataaaa ttatagttga tagttcataa 83281 tcagaaaata tttccagatg ccagttatgt tctctgactt ttctccttca agagagtaat 83341 tgcttactcg agtaggtggg ccttgtttta aaattcatgt aagatataac ttctgtccct 83401 agcttaggcg gacttagaga tttcataaga aagtttggcc agacacagtg gctcacacct 83461 gtaatcccag cactttggga ggctgaggtg ggtggatcac aaggtcagga gatcaagatt 83521 atcctgggca acatggtgaa accatgcctc tactaaaatt acaaatatta gctaagcatg 83581 gcagcatgca cctgttgtcc cagctatttg ggaggctgag acaggagaat ggcttgaacc 83641 tgggatgcag aggctacagt gagccaagat cacactgctg cacttcagtc tgggtgacag 83701 agcgagactc catctcaaaa aaagagagaa agttttagtt aaatggacat aactggagat 83761 cgcttttaag atggccaaat aggaacagct ctggtctgca gctcctagtg agatcgacac 83821 agaagatggg tgatttctgc atttccaact gaggtacctg gttcttctca ttgggactgc 83881 ttggacagtg ggtgaagtgc acagagggtg aactgaagta gggcagggtg tcacctcacc 83941 tgggaagtgc aaggggtcag cagatttccc tttcctagcc aagggaagcc gtgacagact 84001 gtatctgaag aaacggtaca ctcttttttt tttttcaatt tttaaaatag ctttattgac 84061 atataattgg catccagtac acttcatgtg tttacaatat aaaatttgat ctgcattgac 84121 acaggcacac acctacaaaa ccatcacaac aatcaaccat caccagcaca tccatcacca 84181 ccaaaaagag aaacggtaca ctcttgacca aatagtgcac ttttcccatt gtcatagcaa 84241 atagcagacc aggagatacc ctcccatgcc tggcttggtg ggtgccacag ccacggagac 84301 ttgctcactg ttagcacagc agtctgagat caacctgtgg ggctgcagct tgatggggag 84361 aggggcatct gccattgctg aggcttgagt agctcacagt gtaaacaaag ctgccaggaa 84421 gctcaaactg gctggaaccc accacagctc agcaaggcct actgcctctc tagatttcac 84481 ttctgggggc agggcatagc agaacgaaag gcagcagaca gattctgcag acttaaacat 84541 ccctgtctga cagctctgaa gagagcagtg gttctctcag catggcattc gagctccaag 84601 aacagacata ctgcctcctc aagtgggtcc ctgaaccctg tgtagcctga ctgggagaca 84661 tctcccagaa ggggagcaaa gacacctcaa acaggtgggt gcccctctca gatgaagctt 84721 ccagaggaaa gatcgggcag caatatttgc tgttctgcag cctccactgg tgatgcccag 84781 gcaaacaggt tctggaatcg acctccagta aactccaaga gacctgcaac tgaggggcct 84841 gactgttaga aggaaaacta acaaagagaa aggaatagca tcaacatcaa catcaacaaa 84901 aaggacatcc acatgaaaac cccatctgta tgtcaccaat atcaaagacc aaaggtagat 84961 aaaaccacaa agatagggag aaaccagagc agaaaagcaa aaaattaaaa aaaaaaaaca 85021 acagagcgcc tcttctcctc caaaggattg cagctcctcg ccagcaaggg aacaaaactg 85081 gatggagaat gagcttaacg agttgacaga agtagacttc agaaggtcag tagtaacgaa 85141 cttctctgag ctaaaggagc atgttctaac caatcacaag gaagctaaaa accttgaaaa 85201 aaggttagac gagtggctaa ctagaataaa cagtgcagaa gagaccttaa attacctgat 85261 ggagctgaaa accacagcag gagaacttca tgatgcatgc gttatcagtg actgaaggtc 85321 aaattaatga aataaagtga gaagaataga gaaaaaagag ggaaaaaacc taacaaagcc 85381 tccaagaaat atggggctat gtgaaaagac caaatctatg tttgattgat gtacctcaaa 85441 gtgataggga gaatggaacc aagttagaaa acactcttca ggatattatc caggagaact 85501 tccctaacgt agcaaggcag gccaacattc aaattcagga aatacagaga acaccacaaa 85561 gatattcctt gagaagagca accccaagac acataatcgt cagattcacc aaggttgaaa 85621 tgaaggaaaa atgttaaagg cagccaaaga gaaaggtcaa gctacccaga aaggaaagtg 85681 catcagacta acagcagatc tcttggcaga aaccctacaa gccagaagag agtgggggcc 85741 aatattcagc attcctaaag gaaagaattt tcaatccaga atctcgtatg cagccaaact 85801 aagcttcata agtgaaggag aaataaaatc tttcacagac aagcaaatgc taagagattt 85861 tgtcatcacc aggcctgcct tacaagagct cctgaaggaa gcactaaaca tggaaaggaa 85921 caacctgtac cagccactgc aaaaacatgc caaattgtaa agacatcgat gctatgaaga 85981 aactgcatta attaatggac aaaataacca gctaacatca taatgacagg atcaaattca 86041 aacatagtaa tattaacctt aaatgtaagt gggctaaatg cccaaattaa aagctacaga 86101 ttggcaaatt ggataaagag tcaagaccca tcagtgtgct gtattcagga tacccatctc 86161 atgtgcaaag atgcacatag gctcaaaata aaaggatgga ggaagatcta ccaagcaaat 86221 ggaaagcaaa acaaacaaac aaacaaaaaa agcagggatt gcaatcctag tctttgttaa 86281 aacagacttt aaaccaacaa agatcaaaag agacaaagaa ggccactaca taatggtaaa 86341 gggatcaatt aaacaagaag agctaactat cctaaatata tatgcaccca atacaggagc 86401 acctagattc ataaagcaag tccttagaga cctacaaaga gactcccaca caataataat 86461 gggaggcttt aacaccccac ttcagtatta gacagatcaa caagacagaa ggttaacaag 86521 gatatccagg acttgaactc acctctggaa caagtggacc taatagacat ctacagaact 86581 ctctacccca aatcaacaga atatacattc ttgtcagcac cacatcacac ttattctaaa 86641 attgaccaca taattggaag taaaacactc ctcagcaaat gtaaaagaac agaaatcaca 86701 acaaattatc tgtcagacca cagtgcaatc aaagtacaat tcaggattaa gatactcact 86761 caaaactgca caactacatg gaaactgagc aacctgctcc tgagtgacta ctgggtaaat 86821 agcaaaatga tggcagaagt gaagatgttc tttaaaacca gtgagaacaa acacacaaca 86881 taccagaatc tctgggacac atttaaagca gtgtgtagag ggaaatttat agcactaaat 86941 gcccacaaga gaaagaagga aagatctaaa attgacaccc tgacatcaaa ttaaaagaac 87001 tagggaaggc caggcgaggt ggcacatacc tgtaatccca gcattttggg aggctgaggc 87061 aggcgaatca cctgaggtca ggagttcgag accagtctga ccaacatgga gatactccat 87121 ctctactaaa aatacaaaat tagcctggtg tggtggcaca tgcctgcaat cccagctact 87181 caggaggcta aggcaggaga atcccttgaa cctgggaggt ggaggttgca atgagccaag 87241 attgagccat tgcactccag cctgggcaac aagagggaaa ctccatctca aaaaaaaaaa 87301 aagaagaaga aaaaaaaaaa agaacaagga ctagggaagc cagagcaaag aaactcaaaa 87361 gctagcagaa gtcaaaaaat aagttcagag cagaactgaa ggagataaga gacacaaaaa 87421 acacttcaaa aaaatcaatg aatccaggag ctggtttttt gaaaagatca acaacacaga 87481 ccgctagcaa gactaataaa gaagaaaaga agaaataatc aaatagacac aataaaaaat 87541 gataatggag atatcaccac tggtcccaca gaaatacaaa ctaccatcag aatactataa 87601 acacctctat gctaataaac tagaaatcta gaagaaatgg atatattcct ggacacatac 87661 acccacccaa gagtaaacca ggaggaagtt gaatctctga atagaccaat aagaaggtct 87721 gaaattgagg caataattaa tagtctacca accaaaaaaa gtccaggact agacagattc 87781 acagccaaat tctaccagag gtataaagag gaactggtac cattccttct gaaactattc 87841 caatcaacag aaaaagagag aatcctccct aactcatttt ataagaccag gatcatcctg 87901 ataccaaaac ctggcagaga cacaacaaaa aaagagaatt ttagaccaat atttctaacg 87961 aacatcaatg agaaaatcct cagtaagata ctggcaaaca gaatccagca gcacatcaaa 88021 aagcttatcc accactatca agtcagcttc acccctggga tgcaaggctt gttcaacata 88081 cacaaatcaa taaacgtaat ccatcacata aagagaacca agaacaaaaa ctacatgatt 88141 atctcaatag atgcagaaaa gacctttgac aaaattcaac agaccttcat gctaaaaact 88201 ctatataaac taggtattga tggaacgtat ctcaaaataa taagagctat ttatgacaaa 88261 cccacagcca atatcatact gaatgggcaa caactggaag cattcccttt gaaaactggc 88321 acaagacaac gatggcctct ctcaccactc caattcaaca tagtgttgga atttctggct 88381 agtgcaatca ggcaagagaa agaaataaag ggtattcaat taggaaaaga ggaagtcaaa 88441 ttctgtttgc agacgacatg attgtatatt tagaaaaccc cattgtctca gcccaaaatc 88501 tccctaagct gacaagcaac ttcagcaaag tctcaggata caaattcaat gtgcaaaaat 88561 gacaagcatt cctatacacc aataatagag agctaaatca taagtgaact cccattcaca 88621 actgtgagaa agagaataaa atacctggga atccaaatta caagggatgt gaaggacctc 88681 ttcaaggaga acaacaaatc actgctcaac gaaataaaag aggacgccaa gaaacggaag 88741 aacattccat gctcatgggt aggaagaatc aatattgtga aaatggccat actgcccaag 88801 gtaatttata gattcaatgc catttccatc aactagcact aattttcttc acagaattgg 88861 aaaaaactac tttaaatttc atatggaacc aaaaaagagc ccacatagcc aagacaatcc 88921 taagcaaaaa gaacaaagat ggaggcagca cgctacctaa cttcaaacta tactacaagg 88981 ctatagtaac caaaacagca tggtactggt accaaaacag atatatagac caatggaaca 89041 gaacagaggc ctcagaaata acaccactca tctacaacca tctgatcttt gacaaatctg 89101 acaaaaataa gcaatgggga aaggattccc tatttaacaa atggtgctgg gaaaactggt 89161 tagccatatg tagaaagctg aaactggatc ccttccttac accatataca aaaattaact 89221 caagatggat taaagactta aatataagac ctaacaccat aaaaattcta gaagacaacc 89281 taggcaatat cattaaggac ataggcgtgg gcaaagactt catgactaaa acaccaaaag 89341 caatggcaac aaaagccaaa atagacaaat gggatttaat taaactaaag agcttctgca 89401 cagcaaaaga aactaccatc agagtgaaca ggcaacctac agaatgggag aaaatttttg 89461 caatctatcc atctgacaaa gggctaatat ccagaatcta caatgaactt aaacaaattt 89521 acaagaaaaa aagccccatc aaaaagtggg caaagaatat aaacagacac ttctcaaaag 89581 aagacattta tgcagccaac agacatatga aaaaaagctc atcatcactt gtcatcagag 89641 aaatgcaaat caaaactaca atgagatctc attttacacc agttagaatg gtaatcatta 89701 aaaagtcagg aaacaacaga tgctggagag aagtggagaa ataggaacac tttcacatgt 89761 tagtgggagt gtaagttagt tcaaccattg tggaagacag tgtggcaatt cctcaagtat 89821 ctagaactag aaataccatc tgacccagca atcccattac tgggtatata cccaaaggat 89881 taaaaatcat tctactataa agacacatgc ccacgaatgt ttattgtggc actattcaca 89941 ataccaaaga cttggaacca acccaaatgt ccatcaatga tagactggat taagaaaatg 90001 tggcacacat acaccattga atactatgca gccataaaaa aggatgagtt catgtccttt 90061 gcagggacat ggatgaagcc tgtaaccatc attgtaagca aagtgtcaca aggacagaaa 90121 accaaacacc acaagttctc actcaggtgg gagttgaaca atgagaacac atgaacaaaa 90181 tgcagggaac atcacacacc ggggcctgtc agggggtagg cagctgggag agggatagca 90241 ttaggagaaa tacctaatgt aaatgttgag ttgatgggtg cagcaaacca acatggcaca 90301 tgtatacgta tgtaacaaac ctgcaggttg tggacatgta ccctagaact taaagtataa 90361 taaaaaaaaa atggacataa ccataggcca tcacttacYa caccaatgtc cacagtgtgc 90421 aatacagctg tcaatgatta aacaataatg aagttctaag aacattttgg tttacttttt 90481 ttgagtctgg agtaatgtga aagtctaaaa tgtgtgtcag tccaagcaat aaggtttacc 90541 tgcccccatt tctttctgcc tctatttctt ttttattaga cctatgaaaa gctcttcctt 90601 ggtttttgaa taattgaatg ctgtgaatac taatcaatag aatcatagga cccacgtcat 90661 gacatagaaa caaacaagtg ttgttttatc atctctagtt ctatggcatg ttgctggaag 90721 ggatgaaaga acaggcagca aataattgag tatgttgggc tgggcatggc ggctcatgcc 90781 tgtaatccca gcactttgag aggccgaggc aggcagatca cctgaggtca ggagttcaag 90841 aacagcctga ccaacatgga gaaaccccat ctctattaaa aatacaaaat tagctggcca 90901 tagtggtgca tacctgttac cctagctact caggaggctg agcaaacaaa tcacttgaac 90961 ttgagaggtg gaagttgctg tgagctgaga tcacaccatt gcacttcagc ctgggtaaca 91021 agagtgaaac tctgtctcag aaaaaaaaaa aaaaagaatt aagtaagtcg aagtcacact 91081 gatcacagcc aatttttgtg aaccaaggaa ggttctattc aataattaac atagattttt 91141 acttttgcta tctcctgtgt gccacgcaaa atatagactc tggagaatca gaagcaaaag 91201 aaactcactt gttcctctca caatactcag tacttactta gataaggaca aaataaaatg 91261 tcctgtctgg aatgcaggga aaccagaact tcaggtcagg ggatacttca gttgaattgt 91321 atggagatta agcttaaaat attatgaatg tatcttaaat tcactttgtc tttacttgat 91381 acatccatca catagacatc atgcagtggg cacctacaat aggtttaatc actgctcact 91441 tctgttggat caacaagaaa tcaactcata tgacagtgat gagtctcaga atgagaggag 91501 gtgccagctg ggcctcttgg gttgagtagg ggctcagaaa gctgtgaaac tcactcattt 91561 ccctgcatca ggacttactt cagtcctgga tgaataatat tgaagatata tgcttaaaat 91621 attcctaaca ccagaatttg tgcattgtgt tttcttcccc aagaaagcta taaacagcaa 91681 aaaaattttg ctgtaagttt ccctgtgtcc tatttctctt ccccctaccc caaaactaaa 91741 aggaatgtta actgctcatt tttctgtgac cagcagacct tatctatgct cccaattcca 91801 atttcttata aaagtacttt gtaaggtcct gtaagatcct gtctccttta ccatgctact 91861 gcaaggtcat aaagtagcta aaacctaagt tgcaattcca gttttcctca aaatctaaga 91921 catgtcacaa aataatttac tgcctttgtt tctcaatctg gtaacatctt cccaccacac 91981 atatttcctg ccttaaagag ttgaaaaggc aattgtataa tctcactctg gttacctgtt 92041 caggacacct tccacagtgt gctttcactc agctcaataa agcctacaac tttttctctc 92101 tctcggtcct tgcctctatc actcaccata gtcagccacc acaccaattc tttggtgtgg 92161 ctaggcaaga accttaggtg ttacattttg gtgagccagg caggatactc caggaaaggc 92221 atctagatca tcacactgtg agtacaatca gacctctttt gcttgctatt ctgtcctgtc 92281 cttccttaga atttggaggc taaactaggc acctgtcagc cacttaaagg tgattagtgt 92341 ggctgctgga ctaaagacac gggtgtcagg ctgtctggaa aaggttctct aacaacccct 92401 gacccttcag gtttgggagc attggttggc ctggaaccag ttccaactct tttgctttcc 92461 atggtggttc tgaagtacac ctgggagtgc tcagtggaaa tcttagtctc ccagatatcc 92521 tagttgagac cacagccctg ccagaggctc cccctgcatg ggttagtgag catgagacag 92581 ccacatcttc tgactcccac ctcctaatga gtcctaatgt ccaccagtta gacttctttc 92641 ctcatcttgt aagcaaggtt attcccacta gacaggatca agattcccta tttagaagac 92701 ttaaagtctt ggggtggcac ccagaagatc cctgttcatg gtgccctcta gggttcaggc 92761 aggtgtcacc atttgatggc tattttgaag gaccagttcc ccaccatagt gtgtagtccc 92821 ccacatcagg ataatttaaa gataggtctg taattttcat gtggatagta gaagccttag 92881 ggcatttcct ccattgctcc ccagataaac tttccccttc cttggggcct atcaagtaca 92941 atctatggtg catgggtaca gctcttagag ccattgaatt gttgtttcaa ccatttaata 93001 attggtattg gaagaaaatg tagtcagttg ggacacagga tactggtacc accttgagag 93061 gggggcttac tcttttgatg gcaagtgggg acagaaggct aaagtacagc agctgttctc 93121 tcagccctgg tctggaggac atccaccacc ccctttaagc ttactaagcc tcctgttgct 93181 aattcagaga tttctccttg aaggacagtt ttatggccag gaccgcataa agtgggcctt 93241 agcattcaag catcagtggt gcccccaacc caggccttgc caccctggaa caggttggat 93301 gtattggcag aaggaccata ataaatccaa cagtccttgt gccccattta gtagtcaatg 93361 ggtgcatggc aggggcaagg gaagtttcca tcctgccagt aagcatggtt aaatctggta 93421 gatggagagc tcaggaaaag cggccatgag ctttcagcac aattagtcct gacccttagg 93481 ggacacccta agggaagatg agtcccagga ctaaccaggg gtgtgggcat ccctgtgttt 93541 aaaattccag atgggcacca caccttccaa accggacact cccttaagat gtatcctgaa 93601 taactgggac aaattcgacc ctgaaacctt aaaaaagaag cagctaattt tcttctgtac 93661 cactgcctgg ccacagtatt ccttacaaaa tggagaaact tggccccctg agggatgtat 93721 taattataac acccttctac aactagctct tttctgtaag caggaaggta aatggagtga 93781 agtcccttac gtacaggctt tctttgccct tcttgacaat actgccctgt gccaagcctg 93841 cgagctttgc ccaaatgaca gaggcccaca attacctcca tattcagggc ctcttccctc 93901 agccccactc tcctcctgca ctgactctcc tccatctggc ctcactgaag tgttaaaggc 93961 aaaatggaaa gagaacgtaa actccgagag ccaggcaccc gaactatgtc ccttacaaac 94021 agtaggagga gaatttgggc gcattcacat gcatgccccc ttctcactct caaatttaaa 94081 acaaataaag gcagatttag ggaaattctt ggatgatcct gataaccata tacatgtcct 94141 gcaaggatta gagcagtcct ttgatctaac atggagagat atcatgttac ttcttgatca 94201 gaccttaagt cctactgaaa aaaaagcagc tttagcagca gcccagcaat ttagggatcg 94261 atagtacctt ggccaggtaa acaatccatt gaatggcctt ggaggagagg gaaaaattgc 94321 ccacagggga acaggcagtc cccactgtaa atccttattg ggatactgac tcagatcatg 94381 gagattagag ccacaggcat ttgctaactt gcattttaaa agggttgagg aagactagga 94441 gaaagcctat gaactactca atgctatcca ccattaccca gggaaaagaa gaaaatcccc 94501 tcagcctttc tagaaatgct gcgggaggct ctaagaaggc acacccccgt aactccggat 94561 tccctggaag gccaacttat tctaaaggat aaacttatca cctaagaagc ggccgatatt 94621 aggagaaaac tccaaaggtc tgccttaggc ccagaacaaa gcttggaggc attattaaac 94681 ctgccaacct cgttgttcta taacagggac caagaggaac aggccaaaat ggaaaagcaa 94741 gataagagaa aggctgcagc cttagtcttg gctctcagac aggcagacct tggtggctca 94801 gagggaacca aaagaggagc aggccaattg cctagtaggg cttgttatca gtgcggtttg 94861 caaggacact ttaaaaaaga ttgtccaact agaaacaaac tgccccctcg cccatgtcca 94921 atatgccaag gcaatcactg gaagtagcac tgccccagag gatgaaggcc ccctgggcca 94981 gaagcaccca accagatgat tcagcaacag gactgagggt gcctggagca agtgccagct 95041 catgcaatca ccctcacaga gccctgggta agtttgacca ttgagggcca ggaagtacac 95101 ttcctcctaa acactggccc agctttctca ggattaatct cctgccctgg aagactgtcc 95161 tcaaagtcca ttactatctg aggaatctta ggacaccctg taaccaggta ttactctcac 95221 ctccagctgc aattgggaga ctttgctctc ttcacatgcc tttcttgtta cgcccaaaag 95281 tcccacaccc ttattaagga gagacatatt agacaaagct ggagctatta tctacataaa 95341 tatagggaac aaattaccca tttgttgtcc cctacttgaa gaaggaatca actctgaagt 95401 ctgggccttg gaaggacaat taggaaaggc aaagaatgcc catccaattc aaatcaggct 95461 aaaagacccc accacttttc cttatcaaac gcaatatccc ttaaggcctg aagctcacaa 95521 agaattacag gatattgtta gacatttaaa agctcaaggc ttagtaagaa aatgtagcag 95581 tccttgcaac accccaattc tagaattaca aaaaccaaat agtcaacgga gactattgca 95641 agacctcaga atcaatgagg cagtaattcc tttatatcct gctgtaccta acccctatat 95701 gctgctctct cagataccag aggaagcaga atagttcact gttctgcacc tcaaagatgc 95761 cttcttctgc attcccctgc actctgactc cctagtcacc ctacaaagcc agcttaattc 95821 tctcgctgca gtagtcctcc aaaactgaag agccctagac atagtaacag ctgaaagagg 95881 aggaacctac ctcttagaga agaatgttgc tatttcatta accagtcagg aatcattact 95941 gaaaaggtca aagaaataag agaacggata gaaagtagga aaaaggagct tgaacactca 96001 ggactggaat atgtttaacc aatggatacc tgggctcctc ccctttctag gccctgtgac 96061 agccatccta ctattactca cctttaggcc ttgcattttt aacctccttg tcaaatttgt 96121 ttcctccagg atcgaggcca tcaagctaca aatggtctta caaatggaat ctcaaatgag 96181 ctcaactcat ggcttctagt gagaaaccct ggaatgaccc gttggtccct cattagccta 96241 gaaagttccc ctctggagga caccacaact gcagggcccc ttcttcatcc ctaaccagca 96301 ggaagtagct agaagaacca ccactcagct cccaacagca gttggggtgt cctatttaca 96361 gg.ggggactg agaggaggtg ccagctgggc ttcctgggtt gagtaggggc tcagaaagct 96421 gtgaaactca ctcatttccc tgtgtcagga cttacttcag tcctggatga ataatattga 96481 agatatatgc ttgcttaaaa tattcctaac accaggatct gtgcatgtgt tttcttcccc 96541 aagaaagcta taaacagcaa aaattttgct gtaagtatcc ctgtgtcctc tctcccttcc 96601 ccctcccctg aaactaaaag gaatgttaac tgcccatttt tctgtgacca gtggatctta 96661 tctatgctcc caattccaat ttcttgtaaa catgctttgt aacgtcctgt aagatcctgt 96721 ctcctttgcc atgctgctac aaagtcataa agtagacaaa acctaagttg caattccagt 96781 tttcctcaaa atctaagaca tgtcacaaaa taatttactg cctttgtttc tcgctctggt 96841 aacatcttcc taccacacct attccttgcc ttaaagagtt tgaaaggcaa ttgtataatc 96901 tcactctggc tacccattcg ggaccccttc cacactgtgg aaactttgta ctttcacacc 96961 aattctttgg cgtggctagg caagaacctt agacgttaca agaggattgg catctcaccc 97021 cttgccatac agataagtag aaagggtggc attcaaaatt aatggccagt ctctaagtcc 97081 caggcactga acttcatggt cttccaacac tcaaaaagtt gtaagcagag gtcagaggtc 97141 ttaaccatag ccatatctga gttgcatttt gaaacagttt ccagcttcct cagtaggaat 97201 ggaagccaaa ctccaaattt atgactcctt tgaggaagtc aagagctgta aggaaagcca 97261 ggggcagggg caagggagag atgccccttg aatgatcctg tgccagttct ttctgggatc 97321 tttgatgtca tcttagctgc cctttctata cttgacatag tgaacgtggc atccactggt 97381 ctagctgtgg tctaccagga acccccaaag ggaagggcac agtgagcagg ggcatctgcc 97441 cgagtgacaa ggatttgaga gggcaggttg gatgcaggga gaggactggc caaatgccat 97501 gagtctggac gtagactgcc tggttcaaat gggaattcac ccttttcgac ttcatgatct 97561 gatacaagtt atatgaaaat gcgtcacaac ttttctagtc tgttaaatga taatgaaatg 97621 tgcactaata actgggagaa gactacacag atgaaatgaa acaagctgca tagaccacag 97681 agctaagaag gtggcactta¹ ggaagccctc agtaagagtt cttggtgcca tggtatctgc 97741 catcttcctt tttatcctca tcatcacctt cataatcttt ctgttgtgct tagggaatag 97801 tttagaggaa ctcattccct gctatcatga gtgagatgtc tatgaaaagg acaaccattg 97861 gtggggggga agcaaaattt tgaataacat ttYtgagacc cccaccacaa ccaagaacag 97921 aaactccaca gtctgctgag ctgacagttt gcatattggt ctcctcccat ctgcccactg 97981 cactctcctg tttgtcctga ggatgaggaa acaaagcaac gctcccaacc atccctcagc 98041 actcactgaa ctgcccctcc cctctgctgg gccatgacca cggagaacag gtccactgtc

[0303] Following is a SPUVE genomic nucleotide sequencethat includes the SPUVE SNP "SPUVE-AA" (SEQ ID NO: ).

TCTAAGGATTCCTCTCCACACCCTGATTCCTGAGGAGTGTTCAAAGACTCAGAAACAATGACAGGCCTGCTGCTGAGCTTT GCTGTCTGCAGTAAATGAACGTTCAGCCCTTGCCCTCCTGACCTGCTTGTCTTTGTTTCTACAGAACAGTGCTCGGCATGG CAGGGATTCCAGGGCTCCTCTTCCTTCTCTTCTTTCTGCTCTGTGCTGTTGGGCAAGTGAGCCCTTACAGTGCCCCCTGGA

AACCCACTTGGCCTGCATACC[G/A]CCTCCCTGTCGTCTTGCCCCAGTCTACCCTCAATTTAGCCAAGCCAGACTTTGGA GCCGAAGCCAAATTAGAAGTATCTTCTTCATGTGGACCCCAGTGTCATAAGGGAACTCCACTGCCCACTTACGAAGAGGCC AAGCAATATCTGTCTTATGAAACGCTCTATGCCAATGGCAGCCGCACAGAGACGCAGGTGGGCATCTACATCCTCAGCAGT

AGTGGAGATGGGGCCCAACACCGAGACTCAGGGTCTTCAGGAAAGTCTCGA GGAAGCGGCAGATTTATGGCTATGACAGC AGGTTCAGCATTTTTGGGAAGGACTTCCTGCTCAACTACCCTTTCTCAACATCAGTGAAGTTATCCACGGGCTGCACCGGC ACCCTGGTGGCAGAGAAGCATGTCCTCACAGCTGCCCACTGCATACACGATGGAAAAACCTATGTGAAAGGAACCCAGAAG CTTCGAGTGGGCTTCCTAAAGCCCAAGTTTAAAGATGGTG

[0304] Following is a SPUVE genomic nucleotide sequencethat includes the SPUVE SNP "SPUVE-AB" (SEQ ID NO: ).

GGAAGGACTTCCTGCTCAACTACCCTTTCTCAACATCAGTGAΑGTTATCCACGGGCTGCACCGGCACCCTGGTG[G/T]CA GAGAAGCATGTCCTCACAGCTGCCCACTGCATACACGATGGAAAAACCTATGTGAAAGGAACCCAGAAGCTTCGAGTGGGC TTCCTAAAGCCCAAGTTTAAAGATGGTGGTCGAGGGGCCAACGACTCCACTTCAGCCATGCCCGAGCAGATGAAATTTCAG TGGATCCGGGTGAAACGCACCCATGTGCCCAAGGGTTGGATCAAGGGCAATGCCAATGACATCGGCATGGATTATGATTAT GCCCTCCTGGAACTCAAAAAGCCCCACAAGAGAAAATTTATGAAGATTGGGGTGAGCCCTCCTGCTAAGCAGCTGCCAGGG GGCAGAATTCACTTCTCTGGTTATGACAATGACCGACCAGGCAATTTGGTGTATCGCTTCTGTGACGTCAAAGACGAGACC TATGACTTGCTCTACCAGCAATGCGATGCCCAGCCAGGGGCCAGCGGGTCTGGGGTCTATGTGAGGATGTGGAAGAGACAG CAGCAGAAGTGGGAGCGAAAAATTATTGGCATTTTTTCAGGGCACCAGTGGGTGGACATGAATGGTTCCCCACAGGATTTC AACGTGGCTGTCAGAATCACTCCTCTCAAATATGCCCAGATTTGCTATTGGATTAAAGGAAACTACCTGGATTGTAGGGAG GGGTGACACAGTGTTCCCTCCTGGCAGCAATTAAGGGTCTTCATGTTCTTATTTTAGGAGAGGCCAAATTGTT

[0305] Following is a GRIN3A genomic nucleotide sequence (SEQ ID NO: 2).

GRIN3A REGION GENOMIC >9: 99687501-99782450 1 aatttagtag ttgccattta cttagtgcct agaatttaag cactttatga atgttatctc 61 taatggcaaa acaactccca ttttattgcc aaagaaacaa attcaaagag gttagtgatt 121 attctgaggg cacatagcta gaaagtgatt gagctgtgtt gtgactgtag gtctgtttga 181 cttcaaagct cttgttcttc atatgccttt gt tactaaa ccccagtgtt aaggtccatg 241 ctggcctggt tgcatgaata tcatctgggg aatttattaa ttcatatgga ttatcctgga 301 ccttcaaagg ggttagaatg tagtagccct tataaataaa ctggagtcta gtaagaaaat 361 agaatatttt tatcatgttt taagacattg actaggtgct accaagatgg agaggtcttc 421 cttttctagc cctttgacaa atctcagata gtattactaa cctggagggc agttgtttgc

481 taaactgtga tgtccttgtt ggctctcatg gctggctgtt gatgctgcct gtcagctggg

541 ttaattgtct actgggatac ctgcagtttg cctctccatc atggtagtct caggatggtt

601 ggaattttta catgttggct gacttcttcc agtgagcatc ccaagatcac caggtagaac

661 cttcatggcc tttctgatat agcctcaaaa ttgtgtagtg acatttccat tgggtctcta

721 aagttgaccc agattcaaga ggagggaaca aagatcccac ctcttgttca gaggactttc

781 aaaggatttt tgtgtcatgt tttaaaacct agcacaaagg gtatatatag attaatgtga

841 acttgtaata gtttagtagt taaaatacta aatagtgtta gctggtgtat agctcctaaa

901 tagagtatct gactttagat tatagtataa tctatactgt attgtatctg actctagatt

961 gctctggggt gagcttaaaa aagagtatgg aagttttctt ttgttgtgaa tgaatggatt

1021 accttttgtg ggactgtgga gagaaatttg ggggtaaaaa tggttttttt gaaaaaatat

1081 ttatcttaca aaacaaaaga tactatttat tatctcttaa aaaattacaa aatttttatg

1141 agtttgtggt ctgtccagag aaatggtgct tttcagaggt agaaaaattg ttgaatctta

1201 ggtggtcttt tctttgtgtg agagttctta tagactttag acttaaagtt tgcatgatta

1261 taactgacac agaattgttg gaggaatccg tgatttcatt tttgtaatca tgcattggga

1321 agagggtgaa gcatcttcta tttgcctctt ttctataatt actcataagc aagggttaat

1381 attatggaat ttggtctttt tttgctatat gtttctgaat gtttgtcttt gggatgtagt

1441 tctccaagtt gcagagtaaa gtggagacag ccgaatcacg agtgtctgtc ctggagtcca

1501 tgattgatga cctgcagtgg gatattgaca aaattcgaaa gagggaacag cgactcaacc

1561 gacacttagc agaagtccta gaacgggtca gtgctgtttt atggcttgga gactagaatc

1621 attttaagga gtgttctcag gaagactcac cttggggcat ggtatttgag gaaaaaatct

1681 catcctttga aggtacattg gttatagact gaaatcttaa gagtctctca ctaaagaatc

1741 tttgtgttct ctgtaggtga attccaaagg ttataaggtg taYggagcgg ggagcagtct

1801 gtatggcggc acaatcacta tcaatgctcg gaaggtaaaa tcagtgactc aggacatgtt

1861 ttggactgta tgtcagcttt catgcttagg tacttaggac tgtgttcaca agtgacatca

1921 tggggttttg ctggaatagc gaatcagtga agaaaggaag cttagaaatg atttaagaag

1981 aatacttatt tattctctat ttttctgctt ctctgcagtt tgaggaaatg aatgcagagc

2041 ttgaggagaa caaagagttg gctcagaacc gtctctgtga gctggagaaa cttcggcaag

2101 actttgagga ggtcactaca caaaatgaaa agctgaaggt aggaacgcat ccctgaaggg

2161 cagtaaaatc agacgttctg ctgatcaact cacgtatata catagttgtg aatctgcgta

2221 ttcatgaggg ataagaaaaa tgtagacaaa atccaacatc cttttatgat aaaactctta

2281 acaaattagg tgtaaagaag tgtacctcaa cataataaag gccatataaa acaagcccac

2341 agccaacatt atacccaatg gcgaaaagtt gaaagctttt cctttaagat caggaacagg

2401 ataaagatgc tcgctgtcat tacttttgtc ctagccagag taattaggca aggataagaa

2461 ataaaggcct cttaatcaga aaggaagagg taaagttgtt tctgtttata gatgacatga

2521 ctttatatat agaaaacctt acaggctcca cgaaaaaact gttagaacta taaatgaatt

2581 cagtaaagtt gcaggctaca gaatcaacat acaaaaacaa ttgtgtgtct atataccaac

2641 aacaaactct ataaaaaaga aattaagaaa acaatcccat ttacaatacc attaaaaaaa 2701 attgtgaata accttaacca gggagatgaa agaactgtac actgaatgga taaagaaatg 2761 tggtgtgtgt ttgtatgtga gtgtgtgtgt gtatatgtgc aacagcatgg atatatttag 2821 aggacattat gctaactgaa ataaaccaag cacggaaagg caaatactgc atgatctcac 2881 ttgtatgtgg gatctaaaaa agtcaaaatc ttggaagcag agtgtagaat ggtggttacc 2941 agggttgggg aaatcggaag atgttgggga aaaggtacaa agttttagtt atgcaggatg 3001 aataagttct ggtgatgtgt agcatggtga ctataattaa tgctgtattg tgtacttgaa 3061 atatgctaag agtagatctt aaatgttctt gccacacacg aaaagataac tgtgaggtga 3121 aggatttgtt aattaggtgg attgtggtaa tgatttcaca gtgtatatgt atagcaaaat 3181 gccacattgt ataccttaaa tatgtataat ttttatttgt tgattatacc ttaataaagc 3241 tggggggaac aaagaaaaaa tgttaagttt tgttgatata tctacttctt tacttacata 3301 tttacttatt atatgtactc tgccttgccc tgaaaaggat ttaaagcaac atacaaagat 3361 atgtagacta aatcaaggtg ctgtaatgta ggagttgttg agaaaaatga gaagtagggt 3421 aaactagggt gaggatccaa aatgcattaa agtggggctt gtatacaaga tgtttgcagg 3481 gggcatatat atactgtgga agggaggcca ttcacatgtc agtgcttacc gaagtgattc 3541 cacaggtttg gctctgcagt tttttgctac caaaacagag aaagaaacac gattggtgat

3601 cctgttggtc ttcaaacctg cccagaagaa ttttcttctt aggttgttag tgtaggggcc 3661 agccccacag ggtcggtggg tctctccctg tgtgcggaga cgagagagtg tagaaataaa 3721 gacacaagac aaagagataa aagaaaaggc agctgggcct gggggaccac taccaccaag 3781 ttgcggagac cggtagtggc cccaaatgcc aggctgcact gatatttatt ggatacaaga 3841 caaaggggca ggataaggag agcaagccat ctccaatcgt aggtaaggtc acgtgggtca 3901 catgtccact ggacaggggg cccttccctg cctggcagcc gaggcataga gagagaggag 3961 acagagagag aaacagctta tgccattatt tctgataatt agagactttt aatactttca 4021 ctaatttgct actgctatct agaaggcaga gtcaggtgta caggatggaa catgaaggcg 4081 gcctaggagc gtgaccactg aacaggttag gcctccggat aacggcggac gagcctgact 4141 aatgtcaggc cctccacaag aggtggagga gtagagtctt ctctaaactc ctcccgggaa 4201 agggagactc cctttcctgg tctgctaagt agcaggtgtt ttcccttgac acttacgcta 4261 ccgctagacc acggtccacc tggtaacggg cgtcttccca gaagctggca ttaccgctag 4321 accaaggagc cctctggtgg ccctgtctgg gcataacaga aggctcgcac tcttgtcttc 4381 tggtcacttc tcactgtgtc ccctcagctc ctatctctgt atggcctggt ttttcctagg 4441 ttatgattat agagcgagga ttattataat attggaataa agagtaattg ctacaaactg 4501 atgattaatg atattcatat ataatcatat ctaagatcta tatctggcat aactattctt 4561 gttttatatt ttattatact ggaacagctc gtgtcctcgg tctcttgcct cggcacctgg 4621 gtggcttgcc gcccacatct taggagaaga aaagagattc tggaagtctt tctcactcct 4681 ctttcgatca tagtcatctc tattttacaa gttgtttgta ggttaaatga tatgaataaa 4741 gatgtttgaa ctgaaaaata aaaaacaaaa acaacctaag ttaaatcagt taaaagtgtt 4801 tgagtaatta aatcagatag ttgcttagga gaggcataac tatttttgat accctgtcaa 4861 tttttttctc tgtcactgtt attaaagaga acaagttagt gactggggtc ctcaactatg 4921 tttttaaaat aagcatcctg acaaatttca ctcttctggt ggctcatttg acacagaata 4981 taaaacacat atcaaaacaa ttctaggagg aaagaataca gtatatccag gtaccatctc 5041 ctagttagtc taatttaatt ttggggtaga ttttacataa ctacagcaat gggtagataa 5101 cttaataatc tttataaaat tgtctctctt gtgtaggaca tcagtgagtt caaaatttta 5161 cttcctgtct agcgtctggg gcaatgctag attctgcttc tgactttgct ttgggccctc 5221 ctaaggtgga attgcggagt gcagtggagc aagtcgttaa ggaaactcca gaatatcgct 5281 gcatgcagtc acagttctcc gtcttgtata atgagagcct acagttgaaa gcacacttgg 5341 atgaggctcg gaccctgctt catggcacca gaggaaccca ccagcaccag gttgagctta 5401 ttgaggtaat agccttgcct tgtcttttgt atgtaagctt tcttgcctcc taaattttac 5461 aattttactc cctcatgtgc aattaatctc tcattcattc agctgtcatt catagagtgg 5521 cagtaggtct ttactctggt aggtactggg catataaaga tgagatgaca aaattcctgc 5581 cctcacagat cttgtagtct gcagtaatgg gagaatagta tccattagaa tgcaatgtgg 5641 tacaatggca gcatagccaa aagatgtgat acatgagaaa agagtgtctg atttgactgt 5701 ggaagtttcc tgattccact taaaaaagta aggtataaat attaaggata aattattggt 5761 agttgaaagt aggagaagaa gaattcccgg catgagaaca gcacatataa aggtatgaga 5821 gagcatgaga aatagtttaa tatggctaga gcttacgtgt atgtgagaaa atagtgggta 5881 gaagctgcaa aattacttac atttcttaaa caaaaagcat ataatggcac cagtagatga 5941 tttttttaaa agatagaaac ttttattcat atgttcattt ctgtatcttc catagttttt 6001 aaggtaatgg ttataatagt tggtctttta atatatgcct gacaaatgaa ttgaatacta 6061 ttttacatat gtttatatac tgttttatag tttagttctc caactaaatt ctaatattct 6121 cagaattggt ggccattttc tttatttttc agtatcctgt cagtttccaa attagtcttt 6181 tgtagatatc tggtttcatt acgtatagat tgaactggaa attttcagag taatccatag 6241 aatatgatga tatttctaca ttttaataag aattttttta ttggttcctt tatctgtgtg 6301 tagcgagatg aggttagtct tcataagaag ctgaggactg aagtaattca gctagaagat 6361 acattggccc aggtccgcaa ggagtatgaa atgctgagga tagaatttga gcagaccctt 6421 gctgccaatg aacaagcagg tataatgatt ctcactccat gctgtagttt gctcttaata 6481 ccttccttga aagatacaac acagacccca gggtttgtta atgctgactt caactcagaa 6541 gtcataagta ccttaaatcc tataattcat tttggttcac agcctggatg tttgtttttt 6601 aactcaagtt gaccagtttt gttttcatct tctgagaagg aatcttttat ttggtaattc 6661 tccctatttc tcagtgcctc ctgatgtgtt ctgttctttc tctccttgtg cctttgccct 6721 taccacggtt cctcataaca ttgttgttcc tgtatttaag gccctataaa cagggagatg 6781 cgccacctca tcagtagcct ccagaatcac aatcaccagc tgaaagggga ggtcctgaga 6841 tataagcgga aattgagaga agcccagtct gacctgaaca aggtaaccag agggaataga 6901 ataaatatca tttgctatta atgtcgtaaa gctgcttttg aatgaggtcg gcaatgtggt 6961 tatcataaga gatgtgcatc tttcttttct ttattctccc agacacgcct gcgtagtggt 7021 agtgccctcc tgcagtccca gtctagtact gaggacccga aggatgagcc tgcggagcta 7081 aaaccagatt ctgaggactt atcctcccag tcctcagctt caaaggcatc tcaggaggat 7141 gccaatgaaa tcaagtctaa acgggatgaa gaagaacgag aacgagaaag gagggagaag 7201 gagagggaac gagaaagaga acgggagaag gagaaggaga gagaacgaga gaagcagaag 7261 ctaaaagagt cagaaaaaga gagagattct gctaaggata aagagaaagg caaacatgat 7321 gatggacgga aaaaggaagc agaaattatc aaacaattga agattgaact caagtaagaa 7381 ccacatttag agtaacagtt tcgactgaaa agctaagatt aagacatcat gcatgaaatg 7441 tttggttgat ggcatggctt gtctgatcgt tttaatgttt tagattgtac aattaatttg 7501 gtttcaagtc gtgttcaag,t gcacagccaa aatggcttgc atggctattt agtactttgg 7561 ttcagtgatc gagtatcagc aaaccgatga tggtagcctt atttttatga atccaaatta 7621 aggaaaagga tgtcatgatt gaggtaatac ttctgagaat tattgggaat taactactgc 7681 tcttcactgg atttgagcag attgctggcg ttaattgtaa tttaaatgat attaagtgga 7741 gtatttatat atcactgtaa cttgaacaat atctgatcta tttgcctgag agttaactgg 7801 tttgtgaata tgccatatct ttcttaggag atttactcct atacacattg acacactaag 7861 atagaccttt aacttgttga atttttctgt gtcataacct tatgcattgg cccttctcct 7921 gtataaccaa taacttctct ggcagaacgg cttacttctt gctccttact ttctatggtt 7981 gatcctttgt tgatgtttgg acttgagaga ccactgtgct caaaatgctt gaactctttt 8041 ggtatataaa agtatagtta agaggtttag taatttaata agaggtgaag ttttagtctt 8101 tggctgatgg ttaatcactc agctgtcaaa tctaggatta acagtatatc tcagactttc 8161 aaatttttcc cttttatttc tccctcttga actctttaag gcaatttttt ttttttctgg 8221 tgtggtatca gaatcatctg agtgacttgt ttaaatcact tgtttaaatt tttgaactcc 8281 atccccagac ctactgaatc tcagttaccc agggttgggg gccacagaaa tttgcctata 8341 taacaagtac acaaatgtct gttttataac tttgttagag gactttgaag ggagaaatga

8401 ttcattttta tacagcttac ttttctgtac tttctaagca tatccaaaag tcttttgata

8461 gtctgtgcaa aattttatct tttaggtgtg atatgaaatg taaaatgaaa ctgttttaaa

8521 atattctgct caatcaaaat tcccttgctc tgatgacctt tattttctta ttacattgtt

8581 cccctccctc tactacgcct gtcataggaa ggcacaggag agccaaaagg agatgaaact

8641 attgctggat atgtaccgtt ctgccccaaa ggaacagaga gacaaagttc agctgatggc

8701 agctgagaag aagtctaagg cagaggtatt ctagtctgct attacctgtc cttctggtta

8761 aaatcttcat ttgtgggatt ttcctttata cttgccaacg atataatt'tc tttctttatc

8821 tttaaaataa gtgtttaagt gcaacatttt ctgccttttc aaagaccatc tgaagtagag

8881 attttaaaac tctccatagg atggtaaaat atatctgaat tactggggtt atgagtaggc

8941 tttccaaagt atgtattcct tgtttttcct atgtaattca ttgctacagg gataatcttt

9001 ttcattactt ttgggaggaa tgtcttatgc tcttaaaatt ttgaggccta aaaaaaagga

9061 tgggaaccac tattctaaag aaagttacct gtgcacttct caaaagtgtt gcttatagaa

9121 gcatgtcata gtagaatgga gtgatgttaa aacagatggt gttatgtaat gttttagtat

9181 attatgtacc ttgttctata attctgtaaa gactcttttg gtattatgaa ccttctatct

9241 ttgcacagta ttaattgatt tttgaaaatg tgttataact ttttattttt gtgcaattcc

9301 tttcctctta tagttggaag atctaaggca aagactcaag gatctggaag ataaagagaa

9361 gaaagagaac aagaaaatgg ctgatgagga tgccttgagg aagatccggg cagtggagga

9421 gcagatagaa tacctacaga agaagctagc catggccaag caggtggact cactttcttt

9481 atttaattga ctttttgagt aaatgttact tgacaataag ttattgccag tgaaatttgc

9541 ttttttattt tggtcttttt ttgattgtta atgtgtattt ttcctttttg tgtgtgtgtt

9601 ttaattctta ccttcaagtc ttttatcttt ctgttatttt gttttgtgta tttgtgaggc

9661 aagaaattta cttttattta aatggacatt tattgaagat ctagtctttc tctgctgttg

9721 ttcagacagt tattgaagat ctagtctttc tttgctgacc tggaattaag ggttatagtg

9781 aatataaaat gaaaaataag acataagatt ttatatacat tatgattaca aatatatgaa

9841 actaagaaaa ctatgcttat aaatatatat cattatatat ttctatgtag tacatatact

9901 acacagaaaa actatgctta taaatatgtg atttatatat aataaggata taatctatta

9961 accaatataa taacattgat taagcagtat gttaactatg gctattttgg ggtcatagaa

10021 ctatagagat tgttctcctc cttataatga atatgtatgt atttttaaat gccagggaat

10081 ttttattaaa attcaataat aaagatactg aaaatgcttg aaaaaaccat atatgtattc

10141 tctgttagta caccttcatt gtttctaaga aatagcaaaa taacagtgag atggagtagg

10201 tttaatggta agttgatcat gaagtgcctt gaaaagaaga acttcattag atcctataca

10261 cattcctttt gttaacaagt gtaattttgg gctgggcgcg gtggctcatg cctgtaatcc

10321 cagcactttg ggaggccgag gtggatggat cacctgaagt cgggagttca agaccagcct

10381 gaccaacatg gagaaacccc atcactatta aaaaaaaaaa aaaacaaaat tagctgggct

10441 tggtggcgca tgcctgtaat cccagctact tgggaggctg aggcaggaga attgctggaa

10501 cccaggagtg gaggttgcag tgagccgaga tggcgccatt gcactccagc ctgggcaaca

10561 agagcaaaac tccatctcaa aaaaaaaaaa agtgtaattt tgacttttct taaatctggt

10621 aaatgccact tttttttttc ttccctctct cttaaggtaa ttatcaggaa attatactat

10681 tataggttct agaacaagta aaaagaaaga cactatgttc ttgtatacga tgactatctt

10741 aaaaatgttc agtctttcta agtttatgta ttaatataat gtgatctcat aaaagtgctt

10801 tttttaagtt ttgcttttgt ttattttggt actagaagaa ctggttttaa agtacatgtg

10861 gagaagtaaa caagagtaac aagagaaatt gaaaaagaac agcactgggg tctcttccat

10921 atattaaaac ataaagtttc tgtagatgaa atagcttggg actactagac aggctattag

10981 aactga'atag aaacttgaga agtagttgaa agtacacatg atacttatta tgtgctaaat

11041 acatagtttt aaatcagtgg ggaaaagaaa aactgtgaca tgtgatggga caaaattaaa

11101 aaaaataatg ttagagaaaa gttagataca tacttgaata cactaggatg atttccaaat

11161 ggatcataga tatgatattt taaaaaatgc atccatcaaa aagctagaag aaaaccatta

11221 aattccttta taatttggag tggagacctt tctatgaata aaaggctaga aaacatgaac

11281 aaaaaattga taattttgag ttatttttta aaatgatgca aaacttctac actgcaaaaa

11341 acactgttag caaagccaaa agattaaatg acaaaaagta aaaaatattt ttaactttta

11401 ttacaaagaa ggcttatctg atacaaaaaa aactctccaa aatagggaaa aaaactcaag

11461 aatccagtgg aagaataggc aaaagaaatg agttggttat ggaaagaata caagtggtct

11521 taaccatatg aaaagatgct cagtctcact taaaatgaga tagatataaa gtaaagctat

11581 tattagatac cagtcttcac ctatcagatt gttacaaggc tttagatgtt tgcaactgct

11641 ggaaatcctg tagatccagt attttaattg tggaaaagca tgagaaaatg tgagaggtta

11701 tgatggaagt actcttaacc aattgctgct tgatccgttt gtctagatta aggtaaatac

11761 aattattgtc taatttaact gacgttgagt acagatcaac taataagtat cagaccaaca

11821 attggtgcca gtgacttcag ataatagagc ttctgtatgc ctagtgacaa aacacaactt

11881 cttaaaactc tgtcactaaa ttaatttata tctaaatgaa cagtgggaaa atttagtttc

11941 ctgtgctctt ccattgaagt tggaagattc ttctaaaatc aaatctcttc cttcatcctt

12001 taggaagaag aagcactcct ctctgaaatg gatgtcacag gccaggcctt tgaagacatg

12061 caggagcaaa atatccgttt gatgcagcaa ttgcgggaga aggatgatgc aaatttcaag

12121 ctcatgtcag agcgtatcaa gtccaatcag atccataagt tgcttaaaga agagaaggag

12181 gagctggcag accaggtgtt gactctgaag actcaggtaa ttaggatgag tagagctttc

12241 tattctgttg aaatagggtg ctttctacat gatgatataa gtaaaagaat gattattgtg 12301 gcacattttt gtgattggaa aaaaatttga aaactaaatg ttcatcatta gggtattggt

12361 aaataaatta tacatctcta ctgttattcc tacaaaagag tacagtgtac ttgtcaaata

12421 tggatctgct aatatggaaa catgtctgaa ataaaatcaa gtgacgtgtt ttgttatcct

12481 ttttgcgtta aagtatatgt ttacttgtgt tcctgtgctg tatattttaa aaatttctgg

12541 aaggctgcat gagaaactgt tagaattgtt acttctggat attgggatga gttgtgggtg

12601 aggttaggag gtatgtgtga ttttactttt tttttttttt ttttaaattt ccataggttt

12661 tggggaacat gtggtgtttg gttacatgaa taagttcttt agtggtgata ccaagatttt

12721 ggtgcaccca taacccaagc agtgtacatt gtacccagtg tgtagtctat tgtacccagt

12781 gtgtagtctg ttgtcccttg cctccctccg ccaagtcacc aaagtttatt gtatcattct

12841 tatgcctttg cgtcctcaca gcttagctcc tacttatgag tgaggacata caatgtttgg

12901 ttttccattc ctgagttact tcacttagaa tattggtctc caattccaat tccatccgga

12961 ttgctgtgaa tgccattatt ttgttccttt ttatggctga gtagtattcc atggcgtgac

13021 ttttcctctg ggtagatacc cggaagtggg attgcggaat caagtggtag gtctactttt

13081 agttcattaa ggactctcca tactgttttc catagtgatt gtactagttt acattcccac

13141 caacagtgta aaagtgttcc cttttcatca catccatgcc aacacctatt attttttgat

13201 tttttgatta tggccattcc tgcaaagtga ggtggtgttg cattgaggtt ttgatttaca

13261 tttccctgat aattaatgat gttgaacatt tttcttatgt tcgttggcca tttgtatata

13321 ttcttttgag aattgtatat tcatgtcctt agcccacttt ttggtgggat tgtttgtttt

13381 gttcttgctg atttgtttga gttccttgta gattctggat attagtcctt tgttggatgt

13441 atagattttt ttctcccact ctatgggttg tctgtttacc ctgatgatta tttcttttgc

13501 tgtgcagaag ctttttcgtt taattaagtt tcatctattt atcatttctt ttgttgcatt

13561 tgcttttggg ttcttggtca tgaagtcttt gcctaagcca ttgtctagaa ggatttttcc

13621 aatattgctt tctagaattt ttatggtttc aggtcttaga tttaagtctt tgatccatct

13681 tgagttgatt tttgtatagg gtgagagatg aggatctagt tccattcttc tacatgtggc

13741 ttgccaatta tcctaccacc atttgttgaa tagggtgtcc cttcccactt tatgtttttg

13801 tttggtttgt caaagatcag ttgactacgt atttggcttt atttctgggt tctctattct

13861 gttacattgg tttacatgcc tatttttata ccagtaccat gctgtttttg tgactatggc

13921 tttatagtat aggttgaagt caggtaatgt gatgcctcca gatttgttca ttttgcttag

13981 tcttgctttg gctatgtatg ctcttttttg gttccatatg cgttttagga ttgtttgttc

14041 tagttccgtg aagaatgatg ttggtatttt gatgggaatt gcatttcatt tgtagattgc

14101 ttttggcagt atggtcattt tcacaatatt gattctaccc atccacgagc atgggatgtg

14161 tttccatttg tttgtgtcat ctgtgatttc tttcagcagt gttttgtaat ttttcttgtc

14221 gaggtctttc acgttcttgg ttaagtatat tcctaagtat tttattttat tttttttgca

14281 gctgttgtca aagggtttga gttcttgata tgattctcag tttggttgct gttggtgtat

14341 agcagagctc tgatttgtgt acattaattt tgtatagtga agctttgctg aattcattta

14401 ccagttctag cacctttctg gatgagtctt tagggttttc taggtatatg ataatgtaat

14461 cagcaaacag tgacagtttg acttcctcat taccaatttg gatgcctttt atttctttct

14521 cttgtctgat tgctctggct aggacttcca gtgccatgtt gaatggaagt ggtgagagtg

14581 gcatctgtgt cttgttccag ttctcagggg gaatgctttc aacttttcct tgttcagtat

14641 aatgttggct gtgggattgt catagatggc ttttattacc ttaaggtatg tcccttctat

14701 gctgattttg ctagagtttt aatcataaaa ggatgctgga ttttgtcaaa tgctttttct

14761 gcatctattg agatgatcat gtgatttttt aaaaattctg tttatatggt gtatcagatt

14821 tattgacttg tggatgtcaa accatccctg tatccctggt gtgagaccca cttgatcatg

14881 gtggactatc tttttgatat gctttttgaa ggcagtgtga gaaactgtta gaatggttac

14941 ctctacatat tgggatgagt tgtgggtgag gttaggaggt gggtgtttgt gattttactt

15001 tttacacttt aatattgttt gattctactt tgtgcattaa tttcaaaaaa gactctttta

15061 gaatgtctag ccattctgaa ggaaatactc ttggactttt gtttgagttc taatttatat

15121 gttatagtat gaattgccag gttttaagca ttagcatgca ttctctattt ttggcaattt

15181 ggaaaagaat cttttcagtc atttttcaga ctcttactga atcttccaca atattttata

15241 ttaaaagtaa agctttcagt tatcatagtc ttgatgtatt ttgaagggtt catgggcaaa

15301 atcagtaata gtttgagatt tctaacatac tgtattttgt gggcttatag attaacagaa

15361 tagttttttt tcttttttta atcttttcat ttgtgttaaa atctgatttt ctgttcaaag

15421 gttgatgccc agctacaggt agtaaggaaa ctggaagaga aggagcatct gttacagagc

15481 aacattggca caggggagaa agagctgggt cttaggaccc aagccttaga gatgaataaa

15541 cgcaaggtat gattgattaa tctaatgatg gttagtctca gtggaacaaa taagtataac

15601 actgttgaga ttgtaagttc gctttattcc ttcaacttgg gctaacattt tgcctcactg

15661 gcaataatag gtgatacaat ggtgtcactt atttgtacat cctacatagg caatggaggc

15721 agcccagctt gcagatgacc tcaaagcaca actggagttg gctcagaaga agctacatga

15781 ttttcaggat gagatcgtgg agaacagtgt taccaaagaa aaggacatgt tcaatttcaa

15841 acgagcccag gtaaaagcag ttgtcttttc ttgtcacctt ttaggtgttt tctgaggtcg

15901 gaagtgaccc atatcatgaa agaatcatta gtccaatgta tgtcatttcc tactagactt

15961 gaggaagttt gttgagggaa gagagtaagt ctgttttctt cactgccata tcctcagact

16021 cttttatggt gccttgcacc tagtaggcac aaaataaata tttgttaaat taatgaatta

16081 gtaaattgtt aaagaagtaa cagcatagca gcagtagagg attttcaagt tcttgtataa

16141 tgtctctatt tttgtcatgc tagctgtttc tcatgatgtc tttctgtctt tatccgtaag

16201 tctctgaatt attttaaacc gttctacctt cagcttaaaa ctaattacta taaaacaaaa 16261 tagactgtcc tctaaactct tagatgtgtt ttcacaggac tgaattggta atagatgcaa 16321 ttctaatttg gggatataat tatggttgcc tcttctgaaa caaaagaaaa tatcctgcca 16381 tttgcagttc tctacatttc tacaagataa ttgaccataa aaggatagaa agtcccctct 16441 tttcacaaca gaaaactcaa gtctattatt tttctcaaaa atgatagatt tgggtaagtg 16501 tgtctaatgg gtatgctatc ctgccacagg aggacatctc tagacttcgc aggaagctgg 16561 agaccacaaa gaaaccagac aatgtaccca agtgtgatga gattctgatg gaagagatta 16621 aggattacaa ggttagaaaa aatgccttag tgattagttt tttgtcaaag ctttaagtgg 16681 cctaatagac tgggagaata atttgcatga tagtaaccag agaatggttt attttggagg 16741 ttggggggaa atgatgctct ttttttagtg ccttgtgggt tttcttcttg gttgtgtagt 16801 atatgagagc catttggatc ataaactttc atggttgttc aaactctgac atcttttctt 16861 tttaggcacg cttgacctgt ccgtgctgta acatgcgtaa aaaggatgct gttcttacta 16921 agtgttttca tgtcttctgc tttgagtgtg tgaagacacg ctatgacacc cgccagcgca 16981 aatgtcccaa gtgtaatgct gcttttggtg ccaatgattt tcatcgcatc tacattggtt 17041 gatctaagtc aagagaagaa gaggagctgg ctagtcagga acttattcat taaccaccaa 17101 acctctacct cttctctcct tgactgtcac ctgtaggaca gtttatcagt caactacctt 17161 tcctccagac tttacttcca ggctctcctc ttcagtagct ggatgacttt agcagaaagg 17221 actggtaaat acaagccttg ggtttcagaa tgaattagaa acaaataact cttactgtct 17281 tccctcccag ctttgtttat tttgtgcttt tagacttttc agtgttttct ttttccagcc 17341 cactgtataa acttggattg tccattcctc ctgaagaaat caagttggta tttttgatgt 17401 ggaaaaggga acaaaagtgg aaacatggct acttttgggg agtgatattt taaaaaataa 17461 gttgtctatg ggcacaaagt tttcttcatt tgtgtagcaa acttcttgtg aatgtggatt 17521 acaaaatggt ataattgtgc tactctcccc tgggtggttt gcagccctaa tgaaattatg 17581 tctaggatga ttcagtctat ttcccattta ctagcagagt aacttgttaa gatcagctgg 17641 ctttcttgtt aaagttattt aagttttgaa tgctctacta cttcaagtct ttaaatttct 17701 tgagactaga ataattttaa ataatatgac cctttgtctt ctaatgaaat aaagattgaa 17761 gaggttgagt caggactgag ctggtgaaga aatcttgtgg gta^ttctgga aatttgatac 17821 ggagagaact tggtgagcta tgaattactc tcagtctcct ttttacaggg ttgttgtgat 17881 ccctcttttc cagaaaattc tgtggaatgt ttctgtagga ctttgttctc cacaagcttg 17941 aattaaagca ggattcagtt tgcatttgtg tttatggttt ttctttgaaa cttttgtctt 18001 tattattaca agttgatttt atatctgctg ttatagaatt aaattttctt gcatggaaat 18061 aatcagctta ggttaagagg ttggccttgt ttagagtatt tagatctttg cttaattgaa 18121 gcacttttct cccaattctt ttattgagtc tattctatgg agaaattata cctaaaagat 18181 taatttattt gactactcag ttatctttca tagttcatta ggtggggtaa gagactataa 18241 tttgtttttt gggggagcat attgctgcct ctagctttag ggtgagagtt cttgcattat 18301 gtggtgggtt tttttttttt ttttttgaga tggagttttg ctcttgtcgc ccaggctgga 18361 gtgcagtggc acaatcttgg cttactgcca cctccgcctc ctgggtccaa gcaattctcc 18421 tgcctcagcc tcccgaatag ctgggattac aggtgctcac caccatgtcc agctaatttt 18481 tgtattttta gcagagatgg ggttttacca tgttggccag gctggtctca aactcctgac 18541 ttcaggtgat ccaccttcct tggcctccca aagtgttttg attacaggtg tgagccacca 18601 tgcccagctg cattatgttt tataataacc agcaaaccag aggtttcata aatctctggc 18661 aaggggttgt gtaaaatgga tccttcttga tcaccacctg tcctagaaga caggtaagag 18721 caaattctgt gtctttctgt ggtcaccagc tataatcagc aggatttgca ctgaattcca 18781 caaagtcatg tggtatgaat taagcaatga gtctaattga agaatcttac taggtcatca 18841 agagaggtca tgggtccctt gatccccctg ctcagcaaac acccccaccc ccacagaacc 18901 atcatgacag gattagctcc tgcttctgga cacagtgagt tttcatttag taataggaca 18961 ctttcccctt gcttcttgct cttcttatag ggtaagcttg agcataactt tgttggttgg 19021 gtgcagatat actgcttggt caacaggtgg tttgggcttg gctgttggct gtttgtgaca 19081 attggctgag aaagccagct gcccagcacc aggggaccat agggcctgtg gaatgttgtg 19141 gaggaaacca ctagccccat gggaagttgg atttagagga agttcctcta gttgagatga 19201 gcagggagcc cctgatccca actggcttga ggtcctggca acacaagttg agctctcaca 19261 gtcattttca gataacaacc aaaaatgatg gtgatttttt ggcagttggc ttctctcact 19321 acagaagagg tcaatgaatg cgctttagga atactcccaa actgcatacc aaattttatt 19381 tgtattgtat gtacattatt catagctttt ttggatccta gttagcaatc acagcccttg 19441 atccatatga actttaaagg gtaatttctt taaggtaatg cttataaatg ccaatttcaa 19501 agattattat agaagtccta gaggcttctc atttcttaaa aacacttcag gctgggtgca 19561 gtggctcacg cctataatcc cagcagtttg ggaggctgag acaggaggat tgcttgagcc 19621 caggagtttg agaccagccc aggcaacata gggagacccc gtctctacaa aaaatttcga 19681 aaattagctg gctgtggtgg tgcacacctg tagtcccagc tacttgggag actgcagcgg 19741 gaggatagct tgagcaccgg aggttaaggc tgctgtgagc tgtgattatg ccatggactc 19801 cagcctgggt gacacagtga gaccctgtct caaaaacaaa caacaaccat ttcagatttt 19861 gtagggatgg tctctctctc tcttttttct ttctttcatt gttaccttgg aaatttctta 19921 gtgactttga ccaaagtcag gtgtgctctg aggcatgcat aactacatgg cttggatctt 19981 accttcttac ttactatagg gatctttttc aaaggtattg agctgtttct gcaattgttt 20041 tcttacatga atttccattg caattccttt tcctttttct ctgtccagat ccgtaggctt 20101 ccttgttctt caagggccgg aatttgatgc acatagttta atgtacatgc cactagagtg 20161 atgactgtga tttgattttg tgaagattct agacaataaa taatcatcag tcttctaaac 20221 ctactaggat ggtgatgctt acacttgccg gaagcatatg ctactctcat ctttattccc 20281 attgtcattt gctaggatgt ggaatgccgt tacatattgt tctttgaaga tttatctgag 20341 gactgccaga taaacccatg tcccagtgga tctgcagaaa agttttgatt agtcattatt 20401 gcagaagtct gcttttctga tgttaagaca gatacactga gattagtaga aaaatggtgg 20461 attatgtgta ggttggattg ggtttgcaca ataggaaacc catgacatag aaatacttac 20521 aaattttcta gatcttaaag tttggaaata cttaaaagtg gtcctatcag aaagaatgag 20581 ctttaccttc tgggattcct gcccatgttt ggtctgttcc aaatgttagc tattaaggtc 20641 ttacttatag cctacttcac aattactaaa ggacatgaaa aggacaatgt cttaacagtc 20701 taatccctaa tatctagcag aggcacatag tagtcagtaa agtttttcat gattaaatta 20761 attctgcttc atggttctgc tgccagatct tccgaagtct gctttactgg gccaatgtgt 20821 gattcaaacc ttattactct ttcttttttt caccccctaa gtagaaacaa tctttcccca 20881 tatatcgaag taacccttca aatttgtatt atccaaaaat atatgactac agttttaatt 20941 tattttgtgg caataaaagg aattattatg aattctaaaa ctaacacttc tgtagtggca 21001 gctcatgaga ctgctgagtc tcatgtagct gagacttcac ttactgcaag gcacacatga 21061 taaccactac gctacggaaa cctgcataaa agcttcattt attgtaagtt aacctttttt 21121 ttttttgagg gaagctatgt tcacattaat ataataataa tatgctctga ggatattaga 21181 gctgaaaggg aactcagacc atgtccttat tttagaagtg aggaaatagg ttccagggcc 21241 actcaggtta gccacaggat tgaaatgcta ctatgagaac tccattgttc ttttatccca 21301 atcggagacc tgtactaata gagtacatgt catcaggtag acaataagtg aaaatacttt 21361 ctgagtcatt ttgaagtctt ctaaagactt acatatacct actatactta tccttgatca 21421 ttctaatcta actagactct ttgccaggcc ctggattaga actacatttt gtttctgaat 21481 tcactgagtt cctttagcac cttgttgtag agtagaattg aatcaaggga tcttagattt 21541 cttcctgctc tcccaatcat atgcatttgc tgagtgctta ttgtgattcc aggcattgtg 21601 ttaaatatat ttctcatgaa gtccgacttg cctgcgtatg gtgctgctac ttattagcaa 21661 gttacttcat gtctctatgc ttcagtttct tcatctataa aataataact acatcatagg 21721 gttatatgga ggatgaaatg aatcatcata caggagacat tcagcacagc gcctggcacc 21781 tagtaaatgc tcagcaaatg ctaactttta taattgttga gcaaataaag aaattgatag 21841 atcaactttc gtttccacct acattttctt atttctaggg aaaaaaacaa aacaaaacaa 21901 aacactgaca tcctccctga aatctaagac acacgtttat ccatgtctgt ctgtctctag 21961 tctgcctgtc ctggtaaatg atgtcatggc caactcattc caaaacttca aaaagttaac 22021 tttatctgct cactgtccta caactaaaat gcatgtgagt gacatccagc tccacctggt 22081 ggtgaggatc ctgttctttt actagttgtc tcttcagctt aaaatccttt agtggttcct 22141 gtagtcttca ggacacaaat ccaatttagc acaagtgatc ttgcctctgc ttttctcttt 22201 ccagttcata tagtttgtca tccaccttaa gctgtgtgtt tctattatat taaatgattt 22261 gaaggtccca gtttcttgat tgccatggtt tccctaatct ggaattttgt acatgctttc 22321 ttttagttta gttgcctgtt accctccact gagtctcttc acctcacaca cctgcaccca 22381 catgcacaca tacacacagt gttttcttca ctccaatagt acccgttgtg catttcctta 22441 ttagagtaca caccataaaa tgtcagtttg tgtcctttca ttacactgag ctctatggga 22501 tcagaatctg ctgtttttat ctgtctattt ccagcaacta gccccaatgc ctgggtacaa 22561 ataggcatcc aaaatatgaa tgattgagta atgcaaaaac acccttaggt aagtaggtag 22621 ttgaattaag ttatagtgga tttacatttt catgagattt gattgtttct attcggaaag 22681 aatgtgtgtg aagaaggcaa caggctagca gattcatgaa ggcaaatttg cctgcagcta 22741 aaactgcttg ggttatcaga aactgcccat atgtctggga ctgcagggct gctgctgatt 22801 tgtaactgtg tttgcatcag ttcttggttg ggctagaaag cagaaagaaa agatgctgaa 22861 atgctatttt tatgagacat aggtattaca gtgttgagtt aaatggacca atgaaggtgc 22921 agttacaata tccgcttctc tctctgttct gtggagctag gggccaggcc gaggcatggg 22981 aaagaagcag taaggcagaa agactaaaag gggattcaag gaagaataga aaattgtgag 23041 gcagtgaccg gaatcctgta tggttgtaca aatctctgtt actattacta gttctgcaac 23101 cttgggcaag ttacatagtt tctctgactc ttgttttttt atctgtaaac tggaggtctc 23161 atttacctac ttaagactac atctatagtg cctatcttgt ggggttgtta agattaaatg 23221 agatcatggt ttataataag tacccaatat atgttagttg ttacagtatt acctgtttat 23281 aggttgtaaa aaggtcagat tgagggtggg cgtggtggct catgcctgta atccccacac 23341 tttgggaggc cgaggtgggt ggatcacgag gtaaggagat cgataccatc ctggccaaca 23401 tgttgaaact ccatctctac taaaatacaa aaaattagcc agacatggtg gcaggcgcct 23461 gtagtcccag ttactcgggc gggaggctga ggcaggagaa tcacttgaac ctgggaggca 23521 gaggttgcag tgagccgaga tcatgccact gcactccatc ctggtgacag agcaagactc 23581 cgtctcaaaa aaaaaaaaaa aaaaagaaaa aaggtcataa gttagggacc atacctatct 23641 tcttcactat tgtgtctcca gcacttggca cgtacatgga agctgtttag caaatgtttg 23701 tcgaattact gatgagggtg atcagtacag gattttagag acctctgaac ttgtgctttt 23761 tcctggaatg tctatctcag atgaagccat ttcagttcta cttcatgatg cctgagctct 23821 gagatttctc agcatatctt gtgtttcttc tttggactat agcaaggaaa taagcataaa 23881 tcatagcatt aatgggtctc ctattaagaa ggaactggta tcatgtcaac atttgaatcc 23941 ccaaagacaa agccagcagt acatccaaaa gtgaagtttc tatctgaaca tttattccac 24001 agtcatagaa actgaagatg gaaaagacct gaggacatct aatccatcca tgtggttgta 24061 caagaaaagt ggctggagca aaacagcccg ttcacttcat gctcacaaga cagcatttcc 24121 gttcttcctg gagcggagcg attgcaaaca cattaaaatg aagacacaat gcaaatactc 24181 ttcacaaacc ttaagaaaat acttataaat acattatttt cataaaatga ttagtaacta

24241 aaaaaaaaga gtgagggaat cctggattag atggatagtt taggtgggta aagaaaggaa

24301 taactaaaca gtatagatag taaagtagta ttaatgccta gaaagcaatt tctgaagaac

24361 tggatgggtt ttctgttttt cctatcaaaa atatgagttg ggagaaaaag aggctctaaa

24421 gtagtttctt tcccctttat tctttaccca caccaaggaa gtgcttaact tgctctaagg

24481 ctctaacaga cacagcacca acactgagaa gtctgttacc cagatgataa ggtctgttct

24541 gcttggcact tgctccgctt accacttttc tggctggaag ggaagcagca gctcttgata

24601 gggtttgtgc aatagcaaga ttcatgaata gcagagagtc atctccaggc acattaaaga

24661 cctcgactgc ttgggtccct gtggctgctt cacttggctg tcctggttat tcttccaatt

24721 tgtttttaaa ttttgggaga ttcccctttc tcctccacct ggaagcatac acactctggg

24781 gccttgatta ttcttattta cacgaaccag gtagctatat ctgttccagc tcatctgagc

24841 atgctttatc atgtgcttcc tgtgccagaa aagcaaggta gcgtccctta tctctttctt

24901 ctttaccaga ataccaccct ctatctgaag gcttctgatc tttgtgtttt ttttgagcct

24961 caaaggagtt gaaagaacag aggcagagct gaacggaaag gaggtttcca aggacccacc

25021 atttcatgac atcattttac aaaacacaat acactgtttc acaaattgca aaacactgtt

25081 cagttactac caataaaaat aaccattgct acttaacatg aagactgctt cgtttcacca

25141 caagcaatta tggtttttct ttattcagaa catagaggca tttcaagcaa tgttgatggc

25201 agtaagcctg ctgtcagccc ctgctgctgc ttgctgcatc ctggccagtg ttttggccag

25261 gtagttcctc caaagatgtt tgaggagcgt gcattggtca tctactttgt ggataggcag

25321 ggcgatctgg catgtgatca ccactgctca gaatgcctca ctagagaagc ttaaggtaaa

25381 Yccgatatac aaaaatgcag acttacaaaa cagatacatt aagggataat taattgcatt

25441 acaaaagggt gctttacttt acaaaagaat tcacttctgg gttcccttaa acagccagct

25501 tctcaaatac agtcagaata tgagctgagt tacaaaaatg tccatgtaca ttaggagcat

25561 ggctgtaatg tggattgagg tacacctgta catcagcctt ccgggctgca cagaggttca

25621 ggggcacgca gagcatggtg gcagagtctc cagcattctt agctggtaca agtgggtggg

25681 gatggctaag gggcaaaatc ttccaaaggc agttgcaacc tacttctggg cctggggtga

25741 gaacgtgagg ggatggggtg tttcaacaca gaactgtcct tttgtgtttt cagggctcac

25801 ctgtttcctc attattgaac tgtttcatct gtggagttgg tgacctctaa ctttagagcc

25861 ctcccacatc catatcagta tctctgagcc tccctccact ccagggtttt ctcagccaat

25921 taatcactag gtgttatcta actacagctt aagttgttat tccctgggtg actgggtaga

25981 ttttggtgga aatgcagaca tttcatccag tagtagaggg agaagttttg tgactgagac

26041 acctttccag tgatctccag ctgtaaaaga ggaaagtgct tggcacagct cctgaactta

26101 ttgtaggcat tcaaattggt tgggggtgga acaatgagtc ctgagaagat aaatcaagta

26161 attgataaat aaggaagtct tgtcctaaat ggtgcccagg ggtgggggtg aggatgttga

26221 aggagagtca gcagatgtgt gctaaaatta ttaaaaagca aaacaaaaca aaacaaaact

26281 tctcaaacag gttttctctt catgcttctc ctcctgcctg tgggcagcca aacttccaga

26341 atggtgtttc tagaaaagta atttttagac cacctgtgtc agtcacttgg gggtgttggt

26401 taacagtagg tttctgagct cacctctaga cctccacccc caaccccata atctctggag

26461 aagggtcttg gcaatccgca ctctgatgag ttctctacta gatgactctt atctacattg

26521 acatttgaga actgacccat attcctttcc cttgctgcct aaacttgata tgctgagaaa

26581 gtgacaccta agcagagggg aggttacttg tatcagtctt tggggggcat tagatgaggc

26641 tggaggatca ttagagggac caaaaccagt tcatagctcc tcagagatga gtgggtgtga

26701 ggatggggga ttgacttgat tttctataca gatatgcaaa gtgcagggca gattcctgaa

26761 tggtcgaagc ttatagtgtt cccgggctgg aggttttggg atttctatgc taagcgatgg

26821 gtgactgctg atctgaaaat ggcctagtgt gtggtgtgta gaacatttca cccacagtgt

26881 cacatattcc attataggca ataagggata ttccaggtcc aacctaaggc cacaaccttg

26941 ctttgccttt ttctctcttt tcctttataa aaggcacaca ccatagtgga gatgcttagt

27001 tacattagaa gtagtcttat tcatttttta gccaaattgc ctttctggcc cagagctttt

27061 gttctgaaag catggtatgc atttttaatg cctctgctgc ctgtcttctg tttcYgctta

27121 ccacatcccc tccccttttc acagtagggt gtaagcatgc tcttactaaa cagtcaggat

27181 ggagtcagag atccagaacc ttctcaaaaa catggctctt gcctggtcca atcaatcctt

27241 gacgtttatg atactaatga gttaattttt aaatacccca cccccagtgg gaggtgctct

27301 gctcttacct gctccccatt cagaatgtag gaataaatct agatcgggga gttgtatcaa

27361 aagctacaac cctagataac ctcgttctgt gttacgatga aaaccagcaa cccagtaaga

27421 cataagtgtg agtaacaatt ttatctcttg ttggtagtgc agagaaaggg ctaaaaacca

27481 gaaatattac tgtggcacct ggtgaaaagg ttaacggcag ctggggttat ctggttattc

27541 acagatctct cgcacagagc ttactcctga ctaagattct tgctagaaaa acactcctac

27601 cctggagacc tagagagtga gcttgagagg agctgctgct gcactttagg cgagggagag

27661 cagacttgac ctttaagaag acctagacct cagcttcccc acacctttgt cgatagttac

27721 aaaagagcat tacaaagtgt ctcaagggct cagaggaagg tcaggaactg agaaagggaa

27781 gcagtgtggt cacctaggac tcacaagtcc gacttgtcct ttgatactcc tccagctccg

27841 ttttcctgct cacagccagc tgcagctcct gacggatcac ctgaatctgc ttctcgagct

27901 ctgagagttc ctgcatcact gagttccgag atacatttag ggagtctgct ttcccattgg

27961 tggtccgcaa ggcagggagc tctcttctcc ttggagggag ggggatgtcc tggtggatcY

28021 ggatgcccag ctggttttgt ccttcctcat cactaaagat gtatttccgt cggttgtcat

28081 gactcagatt ggaagtattc catacggtaa gctgacgggg tcccacatta gacctaggaa 28141 acagagaaat tttagattta ctttccattc tgcagctctc aaggtgctgt cttcatctgt

28201 tagccatttc ctgtgcaata atatggagct gggtgtgcat ttagagatga agtaacaaag

28261 ccatggacag actacctgct agggtgtcat ggggcaataa agagtcatga acatacaaaa

28321 gttcaagtcc catgctgctc tgaaactgga attgggtRtc atttgaaggg atgataggat

28381 ggggtatggt gcattttttt tttttttttt tttttttgca aacaacctca ggtggctttt

28441 aatttccttt ctgcaaggga agctcagaaa ctagccacac cttgaaacgt ttgatgattt

28501 gaaagatgat gctttaataa aagcaaaatc tatttattca cttgttgggt tctgagcatc

28561 aacctgctga cagatctcat aacatggctc atccttagtc ccacaggacc atcctgatgt

28621 ttactacttg atcttgggga gaaaaaaagc atataagcca caggtctcag caaagtgttt

28681 cttactatag ggatgatttt tatgtgagtt gagaatgaca ggtcaggtcc gatgcttaaa

28741 aaaatcccga gaaagccctc agtttcttgc tgggataatg aaagtcatat agaaagcaat

28801 ttgcaatcct gttttaggct tgcatcgtat cacctactac catcatggag agatggctat

28861 agacagcatg agaattattg ccaaatagtc acaggggaag gctgatcctg tttctgaaat

28921 acactttgat acttatgaga taaggagagt ttctcactac aagaatagat tagagcccta

28981 agcagcatag ctgctgattt tttccaccat aggagaagaa gcaggaggag gagtaggagg

29041 gttatgacaa cttttgcaat ctaccacagg acaaaactaa atagaaacac cctaccaagc

29101 cattgtgttt ttgttcccat tcatgtaact gaattgactt ttttcctgga ctcttacttg

29161 ccaggagaag gggacaatct ggaaggagaa ggggaaagag aagaataata aagtctttat

29221 gtaaaagtgg ccataaacct tcttttctcc tttcatttat gccctctgta atgtgacttt

29281 gcagcttgta cctatgctga atctgctttc ctccccgctt cagttaggag tgttctcaca

29341 acttgttttg ggcaacagaa agtggcagac atatcagagt ggcagttcca agcctaaact

29401 tttaagaagt cttgcacatt tccactctct tggaaccctg ctgctgcaat gtgaacaagt

29461 ccagaatggc ctgctgcatg atggtagacc atatggagag aatcctcagg cttcccagtt

29521 gactagctga ggccatcata gaccagacag cccttagctg ctttccccat cccccaaagt

29581 tggctacaga catatgagca aacccagcca aattcagcca agtctggctc agatcagcaa

29641 actgcacagt tgatccatga attagtaagc aacttgctgt tgtttaaaac attaagtatt

29701 gggatgattt atcacatagc aaagaccaac ttatacatga cccaagccat tgaaacacac

29761 actccaaacc accctgtggt tctttaacat gcctcatagt ctaagtttta tataaatgag

29821 cagagggtac cagagctcag ttttcttgta tcctgggctg ggtaaaagtt ctgtaatgaa

29881 cccacttata gctccattgg ctttagacct gagtcagaga ggagatgtaa tttttcttct

29941 agctttataa ttccctttaa tttttttctt caaatctttt cctattgaat ttgaataatc

30001 ttaaagtaat cttggttgtg ctgttatgta gtttgtaatt tttgtgtgtc ttggggtgag

30061 aggaaaggga aaacaggggt gacatgtatt gattgggaac ccagtgagat gaaagataga

30121 ccaaaacctt atgtgaaatc acatgttgaa taaacccagg gctatatata aatcatctcc

30181 tgcaatatgt accttatttt ctttgcatta aatgagaaag ggacaatacc tacttccata

30241 tcatggccca aaatttctcc aagcatttcc tcaaacccat gttaataatt cattcattta

30301 tctatttgct cttttatttg ttcagtaaat atggggcaca gaggagggat gtcaagttgt

30361 agcatgcatg agcatttgca tagatatact tccaagagaa gagagggaga gcattctaat

30421 gccctacaat ggttcatagc agggaaaacc tgagagtaga gcatctacac attttcttca

30481 actgtctaga cagccacagt gataaggtaa gtaaagatag ctggactggt cttctccaga

30541 gctttgtata tctatctggt aatataatat agaagaataa acaaatgctg gactttgtgc

30601 caaattctag ttgctagtat caccaggcat ctgatatttg atgtgggtac ctatgagtgc

30661 aaggtgacaa atgctgagtg taagactcag tgtctacttg gaaaaaataa cccaaggctg

30721 gtgttatact cctagcctca gtaacattta ggctttgctt tgattcaagc cttcgtcagt

30781 cttagagtgt tacatgacca gtgagtgagc tgtatttaac actaaaaatg ggtaaaatag

30841 gcttccctgg agcaattatg taacactgag gttcaatact ccactggact attccaaaga

30901 gacatgacgg ctatggtacg ccaaacactc attgtgtttg acaggttgct aatgttgggt

30961 tgtatagagg taggcacagg aaatgtgagc ccaagctaaa ccatgaacac ctgttctcct

31021 tagatcctca aaataagggg ttcaggaagg gaatctgcca agaaaactgg gtaagttgca

31081 tcaaaagaca caaatggttt tcaatttatg tgagaaagat gtgaatatga atcatatcac

31141 agttggagat gggatcattg ggcttcctgt ttctattata gctggaaaac aaatattttt

31201 tcattgtaag atgatacatt tgctgctatg tcttcttgtg ttactgttat taaaaattta

31261 tgttaaaaat agaaaaaata gatgtaacat gtcatggaac agctgtgact ggactagtat

31321 acagcttgtc actaacacac ttgcaatatg atgcaggaat accacagact gagaggggag

31381 gggagagtgc tcattgactg gaaagagata cttcaagaga taaaggaaat gattccaaca

31441 agctagatgg agactgcata gaaggggact gcagcagtcc cagaaaagat acaaacaaaa

31501 agaatcctgt tttccatccc tttttcttct gttatgatga gaggtgtgcc ctcatctgag

31561 gcctctgggt gtacaaaaga atcagtaggg ttgccttagg cagcaggcag cagagactag

31621 ccaggaacca gacccaagtg cttctgacat ctttagtcac catgaaatag ggaacagtca

31681 tccacagcct ggtgtggtga gagtgaagag cttcgatttt cagatgtcat taatgcattt

31741 aatgtttgtt atttcctatt aataagatgc tctttgctag ggagtttgta gaaaagtgcc

31801 aggaaatgaa ttaggcatga catgtctgtt tcatatttcc aatactctgt tcctaggaat

31861 gctagaaagg agtagggagt ggaaatatgc caaaaagaca gtaaaacatg gaattaattg

31921 cctgcggtat tcattaattc ttacatgtat tttgtacata ataatagcta atatttatta

31981 ggcatttcct ttcattcaga gatgtacatg tatgatctta tttaatcttt acaacaactc

32041 taggaaatag gtactgtttt tatctctact ttacaaatga ggaacttgag gtgcagagag 32101 attaaataag tgacttacac aaagtaacac atatcataag tcttggagac aggatttgga

32161 tccagagggt tgatcctaga gtccatgact acacttctaa ccatgacagt atattgtgta

32221 cactgcattt tagtgtccat atacattttt tattttatgt tttatttccc tctatttata

32281 ctgattcttt tgataaattg ccctgatttg atctgaataa ttatacagtt agatctctaa

32341 agattatttt acaaatataa agacagttgc cattggcccc ttcttacctc ttttccacac

32401 gtttggtctt gaaatgctgc tgcttttcct ctaYaaatga tgtatttatt gctctgtgta

32461 atctctgatg gagaaaacag attcacaggt agaaattatg agaaacacat aggtcaggga

32521 acaaagaacc acttgagatg taacagtata tgtagtcgtt acaaaccttg gcctctttaa

32581 acaaattcca gaaatgccta aaaatagatc aacattcagc ctcaaatctc aacagaacaa

32641 aaattctaat tagaggttat tattccacct ggagaaacaa aaaagtgttc tgatggaaag

32701 ctcagtatta taaaacggta tgtgatataa ggaggcacaa tcataactaa tgtgtagcaa

32761 aaggccttcc ataattgcta aagatgagta aaaagtatat aattaattga caaccaaaac

32821 aaagaaggga aggaggactc ttgagaatta agttaatcat attagcatac aataaggaag

32881 atctgtggag ttctcctaga agaccaaata cttcccagga taaaagtagg aagaacaggg

32941 ttcaactgta accaaaccaa tgatagtaac ctatctagaa aaaaaaaaag tgttaccaaa

33001 gtgaggagtt tagtatgagg gtatatgaat acatgaatag ggtaaatgca gaagtgacag

33061 cctccctgct gggaggtaat ccatggtaca ctggagggca ggaggtggtc tcaccacagg

33121 agaggccagg atggctcatc cagccttgct gtggtcaagt gaaaccactc cctttgttag

33181 agttcttcca tcattatgaa gccttctgac tatattttgg gtctccatgc caatttcatt

33241 cagggagaga tatgcaaacg agtgtgcttg agtcaccagt ctgcttgaca gtttcagttc

33301 tccctgtaaa tcagtgcgtt gatgtctagg taacaggaga gaactgcggc cttgtgaagc

33361 ttggccttgg ccccaatggg tctcaaaccc ctctggacca gggaaaaagc agagagaaca

33421 ggggcaagtg gggtcactta aaggggacca gggactttaa actcacgtaa taggtttcaa

33481 ttttggcaag aaaagaacct aggaaataaa tctttcacac catcttttca gactgtcact

33541 attaagtgaa acctggttaa aaaagttcta tttcttctat tatgaacaac agtggagggt

33601 tataggaaag gaaggagcac tgtgggatgc cttaatttaa gggaaaagtg aattaatggg

33661 atagagagaa ttccttctgc tctaatgaga gtgcctaccc caccctcgtt attgtggtaa

33721 cataacttag tagtctgaca tagggctctg gatcctccca tccctaggaa ttgtacagtt

33781 taagaatatt ggagcaagac acctgtggca ctcacctggc tggtgtggag ccagtattgc

33841 agcttggatt tgtttttgat tcgtggtagc agcagcctgt atactatgtg ctcaccaatg

33901 gtggtcaaaa tggacagacc aaatccaatg cacagcagca caaagagccc agagaagtgt

33961 ttgatgccca tttgcaaagt ctgtgacaga ataggaaaga aaaggccatg aatacaatga

34021 tatacctggc ccaatgcttg tgtactcttt ggttttcaga tggatattca ttttttctgg

34081 actcaaggac agctggagac tatttctccc tgtgtgttct gtgaccttca ttatacatca

34141 tgaaagaaat tcagccaggg ttggactgag ggctgccgag gagcacccaa tgcctagagg

34201 gtgagaaata aaaataaaat taaaagctct ccaaccgact gaacgaactt tctcttgtcc

34261 atggggaccc cgaagaaacc ttaaaaactg agttcctggc cttgattgga tgggaggtct

34321 gtcatgcctc agttgtccct tccttattaa cctttagcca taattcattc ttaagaagta

34381 agcaaaagct agctctggaa aacaagaaac cgataactca ttgctttatc acctttagct

34441 aatcatctaa ggccataacc agattctccc tccctctttg cagtttcagt gtgacagctc

34501 accagtttcc caatgcaccc ttcctaaaaa atgaccacaa tctccagatg gttttggcca

34561 acttgtgggg gatgcatagt gagggttttc atgtcctctg cttcacattt ggacatcaga

34621 agaccaaaat ctccaccctc gggtcatgct aacaccacca ttttttgaac atgggcccag

34681 gaagaggcat gaagctcaac tgcacatgtg catgtatctc ttttcataaa tatttatgac

34741 tcctcctata gcttactcaa tacgtatact cagccacccc actcagcata aattcctgtt

34801 cccttttacc cctcccttga agtgcttgct ctcagcttct gctgaggcta tgcttcccat

34861 tctgcaggat ggctggcctg ctggctgcaa ccctttatga gaactaaaga tctcctggcc

34921 aaatttatga agctcatgat tcttcagttg acaggcgcta ttcgtatgtt aatccactgt

34981 gcaaatggcc cctggagttg tgccaaggcc ctgggtctgg accaccttat ggtctcttag

35041 agattgagag agatagagat agagaattga aacaatttaa tatacctggt agctgtcaag

35101 gaaagaacgt ccctcaggga agagaatgag tagatttaag gggaaaaaga tggtgagttc

35161 agtaactttg gaatttggat ctggtaggga acatggaaat catctagttc atttacagag

35221 gaggaaagtg agaccagaga agtgtagtaa accgagccaa gccacaaaaa aggcatagaa

35281 gagaaagaga aggaacttaa tgatatttat tggttgctta ctttctgcca agtgttttac

35341 attaaaatag atatataacg tctattttat aactaaggaa agtggagtta ctgcaacttt

35401 taagtggcaa agttggtctt tcagtccatt tctgttcagc tccaaagcct gggctctttc

35461 tgctctactg ctatatacca aaacagcagc agttatagca acaatagtag ttacaataaa

35521 tatctgtggc cagcactttg ctaagtgatt tgtgtagatt aagaaaaccc tcacatgtac

35581 tctaaaacag ccattattta gccattgaca tcaatgacaa gagtcaatcc cgtagaagta

35641 aaaatacata atatattgag ttaatactag gtgccaggca ctcttctgcg tatcatggga

35701 tagagataga aggaagttat atctttcctt ttaaacagct tgagtctagg gagaaaacaa

35761 acatatacct ccatgataca tttgatccat gcttcctggg atttgtgggg aagctggttc

35821 atgagataac atttgaataa gacaggcagg atggggaggt tgggtgggga aagtgaacat

35881 actaacctga gggtagcata aacaaaggaa aaaagacatg actttcctgg acagtggtat

35941 agtgttgtga aactgactgc tgtggctgaa ggaaaagtat acaaggcatg aatagtgcca

36001 tagtttgaat gtatatgtcc ctctcaaact catatgttta aacctaaact ccaagggttg 36061 gtattaagag cccttatgaa gggatgagtg cccttataaa agggcttgag gaagctagct

36121 agtccctttt gttgcccttc cagcctttca ccatgggagg acacatcatt tgtcccctgt

36181 ggaggacaag caacaagatg ccatcttgga agcagagact gggcccttac taagacaata

36241 aacttggtgg tgctttgatc ttgaacttcc agcctccaga actgtgggga atacacttct

36301 cttctttata aagtacccag tctcgggtat tttgttataa tggcacacat ggacaaagat

36361 atgcagtgag agagaaacag ggccacacta ggcaaatcct cagatgccgt actaaggagc

36421 ctgggtgtta tccctttgct ggaagctttt ggtcatcatt atcatttata attatttagc

36481 attgaatatg tgtaaggcac aattctgagc actttatcaa tgtagcaact tgccttatct

36541 ttatgacaat ttataaggta aatactggta taatctccat tttataagtg aagaaactga

36601 gcaacaaaga agttcaataa cttgtccaag gtcacatagc tcgtgaaggt tagagctggg

36661 attcaaaccc atgccgtctg ttttcagagc ccacagtctt cactgactca tttgtctgat

36721 gtgaatgatc ctcccattct ctttaaaggt tttcctttca ttctccccac ctctctccac

36781 ctctattctg gagaaacagc cggccaggca tgattcaggc atagggtgca tagggaagtc

36841 tatctggggg tcaggactca gaagaaaagg tcggagattt caggctgtgt tggagcctag

36901 ctcaggaaat ctctttccct ccatgccagt actgcaggct gtgaatcaaa gactagtgtt

36961 agggtcccta gaaaaggaaa gactagagct gagcaggggc tcggagactg gcacaaggca

37021 ggaaaattgg gcagatgact tgggaatgca ggccgaagcc cagccctacg aaacaaggaa

37081 tgctggtctg ggaaagggtt tggtagggaa gcacgttgga ccccaagggc ttcagaggta

37141 ctagggattt tcctgggaca tctctgtgtg caaatggtga ctagttatgt aaacctgaca

37201 tgcagaaagt acatacaaat gtgtctgaaa atagtccttg acctagacct attttaatgt

37261 gtacaggata tggctataat atgaaggatt cagtgagtta ttgctgtgga ttaagaacag

37321 actgggggaa tttagtttgg actgtaacat catcaaacat tcagttaaac tctgagcaga

37381 tgggccctgc ttttttataa gacactgcca agatgaggag gaaagatgta acttgcagtg

37441 agtcatcttg cctttatgga catgactccc tctgtttcct tgtgcataac aatgattagt

37501 cttatttttc tcttagtacc tcaataacaa ataggccgta ttgtttatat tatacatttt

37561 tttctttaaa cttctgctgt ttatacccac atgctgatag actaacagaa gtagttattg

37621 tttttaaatt tggcatttaa* tacatatgcc agatacaata tacctgtatt atgatcttat

37681 aattaccctg taagttaagt gttattatcc ttatttcaca tttgagaaag cagaggttta

37741 taggggttaa taaccttact tacccaagat catgcaagct actaagtcgg gatccaggct

37801 gcggatccag gactgtctga tgccaaagcc tgcaatgctt ctcaaacaat cgccatttat

37861 aggtatcctt ttctagttga atcttcacta ttcgctataa caactatcac aattttttat

37921 ttaaaactca cattggaatg gaaaatccac tatcatctgc ctgtgaacac cagagaaaat

37981 gtttcaattg tgtctgagtc tgagtgacaa gacatacagc tgcctttgta attcagcggt

38041 tcctccccta ggatcacatt gtttaaatgt gctgtgcata tgtgcatctt ccccatatta

38101 tcaagtgaaa actttctttc tagtaaaaaa ctgctcaact tgatactcat tattggtcag

38161 aggaagaaaa gaaggagtta tgaatattca atatcaaata tttaaaatac actcaggtga

38221 tgcagacaaa atgataattg cagctgcaag tgacttgagt ggtagcacat tcagaaatgc

38281 aagcagaagt ccagtctcat gctgtcaagg gccatgtaaa tgaatgcaaa aagaatgcaa

38341 acaaacatat gttttgaggt tgttgttttt tcccccttta tcccattgct tcagctgcag

38401 cttcatttgc tagctcatag ccacacactt ccagagactc aagggccagg gagagaaggc

38461 tgtcacagga ttgattgatt tgattggatt ttttgagaca gagtctcact ctgaggctca

38521 tactagagtg caatggcaca gtcttgactc actgcaacct ctgcctcccg ggttcaagca

38581 attctcatgc ctcagcctcc caagtagctg ggattacagg catgtgttac cacacccagc

38641 taatttttgt atttttagta gagacagggt ttcaccatat tagccaggct tgaactctcc

38701 accttaggta atctgcccgc ctcagcctcc caaattgttg ggaatgcagg tgtgagccac

38761 tgcacccggc tagtcccagg attgagccag ggacaaatct caggcattta ttgctccagt

38821 tggtccttca caaacttact ctagcccacc ccatctcact taggcaactc tttaactagt

38881 aagtaatcat tcaaaaaatt gccttgctca tgtatttcat ttttctaaag gttatttata

38941 ttcattatgt ttctttagca ttttattgtt aatttacatt agtatatatt tactacactg

39001 tgaagaaaaa acatagtttg tatctgatac tgtactctgc atgttgcatg gaggaatacc

39061 aacaaattat gcactataca actaatgttt taaatgcttt atgttatgca gaaattcttg

39121 gtagattgtc acatatccat gcattgtgca ttagatatta aatgtctaca ggtgtctaag

39181 agtgttttag cgaatttagg gaaactgctt gagatttttg gatgaaatag gaatacttta

39241 ttattttttc catttgaaat aatggaaagg gcttccacca tctataaatt tactagccaa

39301 cacatttcta ggaatggacc aaattcagat aaaaggagat gtttgtacta tcacaggtgt

39361 ggtctctgac cagatcagta acatgtatag gataagatta taaactttgt tgttgcccaa

39421 accctgcttt gtattttgtt cagatgtcgt cacttgaaac atctgacagc tggctcgagt

39481 agtgactagt tctcaagtct ccagcaagaa atgcagataa agtgtttcac tcatcatttg

39541 tttttgatgt tactaatcaa gatctatgca gctaatcctt ccttgtgccc attccacacc

39601 tcccagcaca tagcaaccac ctgatttctc tggttttcta gagtgttgtc tatactcatt

39661 gcttctaatt ccttttctcc cattctccct tagaccctct tcaatcagac ttttgtcccc

39721 tcccatcacc tgtcaaacaa ttcctgtaaa agtaaaaaat ggcctccata ttgccaaatc

39781 taacggtcag ttttcacctt attcatgtat cggcagcttg gacgccattg attactccat

39841 cttctttggt atagtttctt aactttgttt ttgtgatact tctttctctt tgttgtacct

39901 tagtctcttt tgcttttctt cttcatcttt ctgactgtaa acataggcat gctttcagtt

39961 tttcagctac actcatgttc tcattcagag tcagctttaa ataccaccca gatgtcaatg 40021 actcccaaga gttgggggct tttctgtcct aacttcctac tctgcctctt tacttaggta 40081 atgaacggac atttcaaaga taacacatta aaagcaaact cctaattttc cctctgaaac 40141 ctgctgctta cacagtcttt ctcatcacaa tgaacctcca tccttgccat gacacaggga 40201 aaaaaacctt agaaccacct ttgattcctg tctttctcta gcatcccatt accctgtgta 40261 tctgcaaata tggtggaacc gaccttcaaa gtatatccag aattcaacat cccaccacct 40321 ccaccaacca ccctgatc^'ca agccaccatc ccctctcacc tcacctagat tattgagaca 40381 gcctcctagt tgttttccct aaccccttct gtcttcttca cagcagtgag aatgactgtc 40441 atgtcactcc tgtgctcaat gcctggtcat ggttttctgt ctcttgcgga gtaaattcag 40501 agtccttgca atgggctatg aggcctcaca agatctattt cctcatatcc ttcttctctc 40561 tcgctggttg actttgctca gccatttggg cttccttatt gttccttaaa tctattgagc 40621 aacttgccac ttgagggtat tttcattttc tgttcgtgcc tgtaaactct tctgccagga 40681 atcaatattg ctccttccct cactttcttt aggtttcttc tcaaatgtca cctatccatg 40741 aagtttaccc taatcactgt gcttaaaaag gcaaattctt ttcccccttc catcctcttt 40801 cagatacaat ctatctctct tactttgctt tatttctctc ttgacatagt ^' atgtgtttat 40861 ttgtttattg cctatttccc cagcaaagta gaatgtaagc tacaggaggg cagcactttt 40921 gtccattttg ctcgatacat actcttgttt agaacagtgc ccagcacggt gaatattttt 40981 taaatgaatg aatgaaagca tatgaaaact aggatttttt gtataaaata aatttgcata 41041 atttccccca cccccgatcc caaacagtct cattatatca cagaagcttc ctagaacagt 41101, tgtttaagag agaagggtgg agatggacat tctcaattaa aaggagagga aacaaggccc 41161 agttttgcta gcctgacctg atcatgctaa tattcaccaa tctagggatc tactgttgaa 41221 actgggacaa aaaatttttt aaattactga agtaaaacac tggaaactga atgcaaaaat 41281 ttcaggagga atgtattgat tttgttttct taggatcctt tctttgggga actgccctct 41341 tcctgcttca tgtggttttg gtgtatctac caatcacaga ctccctgctc cctgttcacc 41401 aggcaaagca tgagactcaa ggccagtcaa tgtgaatctg aaacagaaac actggatatc 41461 aaaggtgttt ggagatgagt catttccaat gtcagtgccc caaagacata gtcccctagt 41521 tcctgcacta gcatccttgg agtgctgtgg ttcgaggctt catctgtcac tctctttctt 41581 acttcaaaac attgagcttt cccgttattc ttttgatagg ttttgcttaa gtttaaaaat 41641 ctgttgcagc cgggcgcagt ggctcacgcc tgtaatccta acactttggg aggccgagac 41701 aagtggatca tctgaggtca ggagttcgag accagcctga tcaacatggt gaaaccctgt 41761 ctctactaaa aatacaaaaa ttagtcaggc atggtggcag gtgcctgtag ttccagctac 41821 tcgggaggct gaggcaggag aattgcttga atccgggagg cagaggctgc agtgagctga 41881 aattgcacca ctgcaatcca gcctgggcaa cagagcgaga ctccatctca aaaaaaaaaa 41941 aaaaaaatct gttgcttgca accaaataat ctgattcaat atatgtactg tttaaaggat 42001 taaggtcctc tagctccgag gtgtgaatat aacttctttt gagatagact gtatcctgac 42061 gcagatctca gaaatgaacg ggtggagcct gttttaggaa gtcttctctg acagggtaag 42121 gctgtgttgc ttttgcctgt ctccagcagc ctagtatata gtaagttcaa taaaaaataa 42181 aaagcacatg tctgaaaagt aacttaatta catttactct gacattccct attaaatatt 42241 tttccccaga gcaaaatgac tgcaagaacc tgggaaaata attgtatttt tcagtgacct 42301 aatgcactaa gctttgtatc atctcctctc tggatctgca cagccaaatg cgatgttcaa 42361 gaattttttt ccttaataag agagctggtg gcagggggag aaataatgat tttaatgaga 42421 ggtaaggaaa agaaaaaggc tgtggtgctt ctgaaatatg gatgactcat agatgcttgg 42481 aagcaggaca aggaagaagc aaatgctatt tctaattttg aagacctggt atctatttta 42541 tttatttatt tatttattta ttgcctcctg attattttgc ccagaagaat agttagttgc 42601 tcaaaagaac ttggcagatt cattgctgtg tctatacata tggccccttg ttggggagaa 42661 gtaggagaat gatatccaca tgaaatgtgg gctccagatg taccaaagac agagtttccc 42721 aggtgagaga gtctggttga agagagttag gtaagattgt gcggtgcaat catttggaat 42781 taaaacatat atatttaaca agaatcatga agagggagaa aaaagattca ttcagagaac 42841 ctggaagttt ctcattaacc aagacatagt gaaagatcac acttaacaaa agaaacagaa 42901 gaggagataa tttattaaca caaaatccag ggagacactg catgagcctg agtagtgctc 42961 acacatttgg ataaacaagg attttgacag cactctctgc attcctctaa cctggaaact 43021 gcttagtggc tcatcaacat ggcactgccc atgttgctgt gaagatgctt ctctctccct 43081 gtttcttggg attcttgagc ccccatttct tttaagcttg ggcgaccatc ttttagggtt 43141 gaaattgtac ttaatttgcc acattagctc tgttgtgcag ttttttgaaa aatttattat 43201 taaaacgact cagaaaaata tttttaaaaa ctaaatgtga gattacccat aatccttgta 43261 ctataaaaca attactttca atgctccatt ttctcttctg aacaatgacc atatgcacac 43321 atattcttca gagttctaaa cataggatat aacaagtttg cattatgctt ttaaaagaac 43381 ttattttcta acaaactatt ttaatatttc taaaaatatt attttctaaa tattatttta 43441 tttattaact ttagttgcct aatactatca cctattgttt ttgttataat tgacttgact 43501 actcccaaac tgtggttgtt taatttttta aatattataa tttatggtat atacgacaaa 43561 tattgctaca ataaaaattt tgtgtatagt attttttttt ctttttttga gatggcgttt 43621 cactgtgact cccagggcag aatgtagtgg agcgatctca actcactgca acctccgcct 43681 ttctggttca aatgattctc ctgtttctgc ctcccaagta gctgggacta aaggcatgtg 43741 ccaccacgcc tggctgattt ttgtattttt ttaatagaga tggggtttca gcatgttgac 43801 caggctggtc ttgaactcct gacctcaagc gatccacctg cctcggcctc ccaaagtgct 43861 gggattaaag acgtgagcct ctgcacctgg ccatgtatag cattttaaaa tatttttatt 43921 tctttgagat atacattgca atgagtgaga ttacctggtc aaaggataca actgttctga 43981 tgacttgtga tgtgtaaaat gacccataaa aagggtgaaa gccattccca atgccaccaa 44041 agatactgca atgcctagaa ggcttctatt tttgccaact gttttataat tattcatttt 44101 tcctgtttta aatattgtaa tttgtattta ttgaattagc aagcctattt ttccatgttt 44161 gttttaccta tctccttttg aatgaatcat ataatgactt ttttgcatat ttatttatgc 44221 atatcagaca caatgaagct tttttttgaa aaactgctaa cccttttgct aacatgttat 44281 gtttctccct ttttatgttt tctttgtttt gttatatttt attatataaa agtttgaagt 44341 tttacacagc tatacttatt ttgattattg tacatttttc tactgtttca ggcattagaa 44401 catattgatt atggggataa atattttgtg tccagtgtta tatctttaaa aaatagtgaa 44461 cccttcagtc cattttgaac ttctgtgcca aagagtgtaa ctatgttaat ttttcttcac 44521 tgaaactctt aatttcatct caatatttca gagactcctt agtcaataaa aagctacctc 44581 catattagag tgacctgcat ttctttgtag taatttaggt ttttatttaa aatctttaaa 44641 ggttttattt aaaatattgg taatttttaa aaaacattgt gagaacaaac accatgtaaa 44701 accagtaaca acgaaagcaa acatttgtag gtcagagtta gcctgtgagt agtcagactg 44761 tcttctgatc tacacagctt tactgctact acggtgaccc ttcagtgtta gaatttttca 44821 ttatgaatca gctaattcct gatgattcat gatttatagt tcacagtcat tggctactgg 44881 ggtaggtacg gtagttgaca cggcagcaga gaagtccggt ctgattctca gtctggtggc 44941 cttgttcctc taccataatg acactctatt tatttattta tttatttatt tatttattta 45001 tttatttatt tatttttttg agatggaatc tcgctctgtc acccaggctg gagtgcagtg 45061 gtgtgatctc agctcactgc aacctctgtc tccctggttc aagcaattct cctgcctcag 45121 ccttccgagt agctgggatt acaggcacgt gccaccacgc ccagctaatt tttgtatttt 45181 tagtagagat ggggtttcac catgttggcc aggatggtct cgatctcctg acctcgtgat 45241 ctgcccgcct cggcctccca aagtgcgggg attacaggca tgagccaccg cgcccggcca 45301 acactctttt taaaaacatc cgagcctcct cctgttcaaa gtattcaaaa tagatataac 45361 accatagcag actaactacc tactctatct cttaacagaa agaaagagtc agtactataa 45421 gtagagaatg gaatttatac tttttttaaa taaaaaattg tcttcattta aaaaattcat 45481 actgttcctc agacagtggc ttaggaattt gtaattaaca aaaatgtctg gaagatattt 45541 tttccttgag aatgtttcta aagcatgaga gaatatacac caaagctaaa ttgaatttgc 45601 tgaggccata tttttttctc tgtttcaaaa agagtgtcta gtggtctggg gattgcaaca 45661 tatggtacag agcagacata atccaattaa cataggattc ataacaacat attgtgactg 45721 atctctatag cctcagagca tattggtttg cgttatcggt ttaatctaaa tattgtcacc 45781 tgtttctcaa gatgagccaa aggtggaaca tggcttaaaa ctgtctcgtc taacatatct 45841 gtttcattgc aatgcataga accaaagagg tggaggctgc ttgttctttg acaagcaatt 45901 tacctctttg ggcttcagtt tcatcattta tgaaaactga ggcttgattt gatgacatgg 45961 ttaagactat aataaataat ttgtaacagg tagatatagg agctataaaa ataagataaa 46021 tgcagagagg tagaaataaa gctcaggatt tggggtcaga aagcctggtt caaatccatg 46081 ctttgccact taccagctgg gcgactttgg agaagatgct agatctctac atggcatcat 46141 ctgtaatgct gaaataatgg caccagactc acagtgttgt tatgatgatt aaatgatatg 46201 tataacaaag gttatatcaa aagttatggg acaattgctc aataaatgtt tattatcatc 46261 atcccaagaa actgtataga actagatttg ttggcaactg gcaattaact gacaggaaaa 46321 acaaagcatt ccgatttggg aataaatgtg attcttttaa cccaaatatc cagttagatc 46381 tttcaagtgc taaatccaga tacaggctct cagttcaagg tcattgccac aaagccttag 46441 gtaactatct tgagtagatt tattgaacaa ttagcttgta aattccagcc actccagaaa 46501 ctgaaacaca tttcctctct ttgttaaatg tgagcatgta atccaatatg tttcaagccc 46561 ttggtcataa ttttaaaatt tccatatttt aatgtgcaca ttgcagggtg tataaataat 46621 gcctctcttt aatgacaata atgtcctctt ggctagcatg acatgtgctc acttcctcca 46681 tgtaaaaWtc ctccacaaaa agttaaatag gttgggctgg aatgagagat tttgttttaa 46741 aaattctcca gttctcaggt cagaaagtct gttgtcccct ctgcaaatga aggagtggtg 46801 aggaccttga aattgttccc attgttttct ctctgggctt ggacatgggc tgtacactaa 46861 tgtccagtta attttagagt gggtgtagct aagaactaag taagtgttca aaagcaacca 46921 gtaagcctca tgtctccttt acatattgat cttgtagaag gggaagaagg gggaagggaa 46981 gggaattagt tgaatgaaag tggaattgtg ctccaggtgt gttgcatgcc tttttgaatc 47041 ctcaaaataa ccctggggtg gatcctcttt aattaggtgg aaagacacag agaggctaag 47101 taaattattc atgctcacac agctaaaaag aagtgagtgt gataacaacc cagttgcaac 47161 tgaatccaaa cccaggtgtg tctgaatctt tgaacattac ataaccctga tcaccacagg 47221 gttgggagcg tttatcacag tttttagggt tgaacaggaa ttgaaggggt aaggattcct 47281 atttttgtgg tttctaagta atctattaaa tacaaaagta tatggtaggg taccttgata 47341 gatgggttcc ctacaagtga ttaaatttgt ggactttttt tttttttttc tattttggtc 47401 aagaccagtt gccagcttct tccaaataaa atagcagtaa atctccttga aacagatctt 47461 ccatgtcctg aaaaaagtta cctgagtggt atctcttggc taagcaagtg tagggagagt 47521 atgtttcatt gttctgctgt tttgagagcc ttaagcatct tatatgggaa gtggttctct 47581 gtgagaaaga ggattggtat ggaggcacag atgctgggac aagtcctagc cctgctcttc 47641 tgaggacagt tcatgctctg agaactcaca atagtatgtg ggacacctca gggagctggt 47701 aacatttggg gtacaggcag tgatgtattt actggtaaac aaattctcca aaacaaaaca 47761 aaaacaacta aaagcttttg ttcttttctc acYatggctg atctaaagct accaacatga 47821 cataaatgcg tgggaagaga cacatgcatt ctggatctcc cctggaacca caggctccgg 47881 ctcacccaat ggtggagatc tgttagtgtg tgaggacttc tgcactgaat gttccactag 47941 ggaaaaggct tcctggaatg agagagctct cagtttctct tctaggcctc agatctgatt

48001 ttcaaaatca gcatagctgg tgtagctagc atccacctct gctgtggaga cacaattgtc

48061 agtctctgca tctgtgagca acagacataa tgccactttg gcatcctagg gagattccac

48121 tgcagcctga ctctactgcc tctcctccgt aggacaacta actaaatgtc tcattgtctc

48181 cacctggggg tagggaccag tgtcggaggt gagagcactt tctgggagaa cactttgctt

48241 gccctattta gctggaggtc cccttcattg aaattaatgc tggtgtgggc tgccaaccct

48301 ggaaacccac tgctaatgag gatgatggct gagctgggca cttagtccag gcttagcatt

48361 tcctataaga gccctgaagc tagtttctgt tcaggagctg gagcaacaag tcaggaggag

48421 gccaaatgaa ctcctacccc tcaaacatgc acagcgattt ctggatgcat tgtggggaat

48481 ggggctgcaa tctgccgaag gaaaagatgg gattctgtcc cctaagaaaa gtgattacga

48541 gatgcccagc aaagacaaat atatttgtcc ctgttgctac aataggaagt taacaatctg

48601 gcaagatatc tgaacacaag caaatgaaaa cagttcacct aacacccatg caaattataa

48661 atttcctccc atatacaaaa tgatgagaaa taacagcaaa aatgtatact ttcttatttt

48721 tgaactttta aagttctagt ttggtctttg aatcaaaaca aagtaaaaga tgtttataaa

48781 agccatttcc ttttctttcc ccactatgct catttgactt gctcttcccc ctatagggta

48841 ccctgagtca ttcagagaag Sagaattaat agcactgagt tggtgatgaa gctcctgtta

48901 ggacatatgg cttcacaaaa agaaatactt ccagataagt cagagagaca gttggacgtc

48961 ttgagcaaat cttgaaagag atagggaaga aagcagaagt tgttgggtgg tgcttgtaag

49021 aaaaaggctc atacgatgag gaccagcttc ttgtggatct ccaggtctct gaccacagca

49081 ctgaattcct caaaggatat cttcccatcg ccatccttgt ccaggatgat gatggttttg

49141 tcgaccagct gctggagctg ccagtccgtc aggttgttgc ccaccatcat cttcagcacc

49201 tggaagagct ccccgttgga aatgtagcca tctttatcca tgtcgtaaat gctgaacgca

49261 aacctcaact tctgctcctc gtcgcccttg acgctgaact gggaggtccc caggatgaat

49321 tccttgaagt ccacttctcc atcaccgtcg gtgtcgaaga cgtcgatcac tcgccgcacc

49381 aacgggttgt ggcgcagctc cggcagggac atgaactcct ccacgctcag agaccctgat

49441 ttgtccaagt ccaacttctt aaacctcctg cccagccttt taatttcatc attgtcaaag

49501 tgggagcaca tctccgccgg gtaactggcc tcgtttccca ttgtggacat ctggcaacgg

49561 ccacggctca aagggtcgga gaggggagca ggggcggtga gctcgggcgg ggctcgtgcc

49621 cggacggttg ggccatgggg tgggggtaga gggctcccgg gggccctggt cgagcaaaag

49681 ggcaggggag cggagggagg ggcggcaggt cagagaggga gcggagagag gagggaaaga

49741 aggagggaaa agggggcgga aggggaggtg ggtgctgtct gggcaggagt atagggagga

49801 gagaatggag cctgggggtg cccgggagag gcagaggtgg aaagctgggc tgccccttct

49861 ctttttcctt ctctcaaact ccttgtacct ttccatgata accccaattt ccctggcaat

49921 tattttatct acttatttct tttttttttt tctctgagaa agtaaacccc aaaggagaag

49981 ggatcgcacc tgtgttattc gctgcagtat cccagaagca cagtgcttca caggcaatat

50041 gtgcttaata aatatacgcc gaatgactga actgcaacca aggacactgt atacttgctt

50101 tacagaccta gtgtaaggat gaaacaaggt gacacatcaa ggcattgata tagtatgttt

50161 tccacgattc cctgggaggg gaagccggga ttgacatcct tctgtacctt tttcaggacg

50221 taggattcag agtgtttgta agagaccagg cagataccgc gcagaatttc ttacatggat

50281 cacctacagg cactaacata ttcccgagga atataaacaa tgctgaattc agggcgtttt

50341 tcaagatgac acaggtctca agaacacaac ctctgttact ctgttccctc ttatccatca

50401 tctcatgccY gagtcacatc tttgttgttg gtgcctggcg gctattctgc agaatacctt

50461 gggggaaggt ctgcaatgtg cccaaagaag ccttttgtgt gtgttgagag tgacagtcgc

50521 ctctggatga tctcactttt ctccttttgt ttcaactaga tttgttcttt ctgttgaaga

50581 ctaatctcac atgctccctc ttattccttc ttcctttcgg agcgcatcaa ttactccaaa

50641 tgcataagaa acaaatgtgg ttcaagagca aacagttcaa agggacttgg gggaacctca

50701 ggccactaca tcaaactgaa agatgcaaac actccttcgc tttaaaaaat gttggcaagt

50761 tctgtgttct atagttcagc caaaatatca gtctaaagat aaccatgctg gaactagcaa

50821 aactaagcca ctgatcacct tatcattaag tctggccatt ttactttcct ctataaacaa

50881 atgataatcc atggatatgt tttaaagctg attatgggca ttacacaaat gaaaccccct

50941 ttcccaatta gactgttata ttggaatgtt tttttgtttc atttatttgc ttgcttttca

51001 gttattcaga gaaatgagca tggtacagtt tgcatataag cctattgaat ttgcaatatt

51061 aaggatacca ccttaaatta tattacaaga tgcctaaaat cagtgttggt ctctaaatga

51121 taccaaccac tatagcctgt gttctttcta aagcacaaag acctttctgg actctctggg

51181 ggaaatatcc aggccctgca ggtgcagttc tgaaaaaatc agaaacctca ggggcaagga

51241 cagaactcta tcttttgggc atgcactggg gctgggagcc tctagaattg tgttatttct

51301 ctcatcttgt gtctttgacc acagtgtagt ccagtttctt ggctgcaagt aaaagaatct

51361 acctctaaga agcttaacat gaaagataat ttgttggaag aatctcacat aatctaaaga

51421 agagctgaat gattcagtct taggaagggt gaggatccca ctgggtttaa ggaaatattg

51481 gaaccaacgc ctcaggacca gttatgtaat ttgcagtgtc ctttgtttga aaatgattga

51541 gagcttcaag atggccacag cagaacatta aaccaagtac gggaccttat gagactgcgt

51601 gggccacatg cccatgaagc tggccctgca aggagttggg cccattgacc tctctgtgcc

51661 tttcacctct gcttctcttt ccttcactct ctcctatggt aaagcaattc ttccacattg

51721 cagaggacac aaccactgac agattccaag ttaagacttt ggggatttta tcatcagaaa

51781 agacggactt ttccctgttc tagttagatg cccataaatc ccatgaacag gctctgattg

51841 gtctcacttg ggttgggttc ccacctatga gccatcagac atggcttata acatatggga 51901 gcttccattt gaacctcatg gatggagctg gtcgggggga agtgggggct gggtaggaag

51961 agcaggtacc aaaagaagca catgctcttc cttataagaa cagggtaatg ctgagcagac

52021 agaacaacag atggacatta gacaggtcca ttagtgctga ctctatagga gagaggaagc

52081 attttgaact cccttcagtt ttgccaactg aataggccac agatcctgct atagttacag

52141 gcctccacta gctcattcat tagtgccagg tccatcttat tatttgctaa aatatccctt

52201 cacctctgtg tagatagaat tggtatctca cttgcagaca ctcttgtgtt tacaaactgt

52261 gggttacaac acattagtga gtgatgaagt tggtttagtg agttacaaac aacatcaaaa

52321 aaatagaaca gcagataatt gaagagaaag tatcatctgt aaggggaagt actattactt

52381 cataaagttg tttataaagt tgtaaaaagt ttacttcata aagttgtaaa actaaatata

52441 gtatatatat gataaaggaa taccaggtca ttctgggttt gcaatatgac atattttctt

52501 gcttggatta tggtaaaaaa taaagacagt ctgacatata ctatagaaca tagtgttttg

52561 atatcttatg ttataggctc atgagccatg agaataattc aacagcaaaa acattttcat

52621 actggttggt tctctgtgag atcagtatgt ggggataaag tagatgaatc ttggaataat

52681 aatctatagc agtgctgtct aattatatat gtacttttaa atttttagta acattaaaaa

52741 gcaaagaagt gaattttaat aatatattta tattaaccca atatatccaa agtgttaccg

52801 tttcaacatg taaccaatat tatcatttat gaatgagttg ttttacactt tttgtactgt

52861 attttatatt tacagcacat gtcaattaga gctcataaca ttcccagtgc tcagtaacta

52921 catgtggcca tcatagtgga cagcacagag ctagacagtt taatggaaaa ggaaagatat

52981 ggaggctaaa atatttgatg gttgaattat tatcccaatt gaattaatta ggttaaaaag

53041 aggtattatt aattaggtat tatattataa ggtagaaagg atttaaaatg ggacaaccca

53101 acatcaaatc ttaacagtcc acttagtagc agtaagacct tggacaagtt gcttgacatt

53161 agttttccca tatgaaaaat ggggctaata atatatattt tgtacatttt tgtgagtatt

53221 aaagctaatg ttagtcaata taatgtcatt atcatcattg ctattattac taattttatt

53281 gttacttacc ctactagtag agatgaagtc ttaaaggata ccagcctgcc ctggacacct

53341 aagtgtacat atagccattt aacaacactc ctcatgtagt ggttacagta tgccacaggc

53401 tgctcacacg ctataccagc ataaaaattg gctcctccag ttcaaaactc tttgaggact

53461 gattacagac cttccattgc agacttgaga aatgcagtaa ccaacatcac tggcccatca

53521 ggcactctta tggattcctc acttacattc tcctgagtaa ttccttgata gtcatttaga

53581 aaggagctcc cagtgtgaaa actcttagct gtatttccct atgtgagtgt gtggttagga

53641 ggtaggaaag ggtaatggag agagcatagg aggtaaatag ttggttccag cctcagctct

53701 ttaccttatt agctgtgagc ctttgagtga agccattgct gtaccagcct caacatcctc

53761 atctgtgaaa tggtgataat acctacacat gcttcatcta ccgatgtgtt attgtaagag

53821 tcagatgagg tagcgtatat agaaatgtta tgtaagaggt gaaatcttgt cacaggaata

53881 ttgaatggtt acacagacag tattaggaag atggtaccac ttcactgaaa taattcaggt

53941 gtacaagcag aaccattcta ctctgtgctg tagaggaggt aacattatgc tagatctgga

54001 gttttagtca atgtgaactt gagttcccat tgttctacct ttcataaact atgtagctca

54061 gcattattat gggactcaac accattgttt tgattttctc tgtaaatgat tcttagtaat

54121 ttccatggaa aacactgttt gttacttttc tgttcatcac tgtggattga tgtggactgt

54181 aggacattca ctgaagcaag taaattaaaa gggttgacta actgttttgg aagaaaccag

54241 gagccttgat ggcacctcta tttcagcatg tcattttttt ccctcaaaag tttttagata

54301 aagaaatatt gagtaggtca catgtaaaaa taactgacat tggaaaatca aaccaacgga

54361 aatggaaatg agacctgagg ttcatataag gcttcatttt tcaagccagt caggagacca

54421 ggtcacacag ctgttctaga agctatacag gtggtccttg acatttggtt ggaagctctc

54481 acctttctgt agcattgccg gtcaccatat ttaatatcta agcgtactga cgttagccac

54541 agtttagact gtggaactac tagctcgagt ttaaactgtt tttgagcatc aggtttgtca

54601 tctgtttggt tttcttttgt aatactgaaa tggtgtttaa tgaattttgg catgtatggt

54661 tttaaatcaa agttttgcta tttaacaact ttgtgacctt gggcagagtt acttatctga

54721 atcttttcac tcatctgtaa aacaaggatg atgattacta actcataaca tcactttcag

54781 gattaaatga gatagattat aagaagaagg gtgctcaatg cctatcacat agtaggtaca

54841 ggaatggtag agattataat tattgcctac tttaggcttg cttaaaaact caagtagact

54901 gtatgcatac atgcacacag atatactcag ctatttattt gttttctcaa caaataatta

54961 ttgaggatct actatgtgag aagaatataa tactgaccta aagtggatac ttttcttgtt

55021 gtccctgttc tcctggagct tacagttttg atgggaagat ggacattaac caaattatca

55081 tgtccataga tgtaaaggag cacctgcctt gagtgttaca gatgagaagt acatggtacc

55141 aggagagttt ggacaacaga aaacttttac tggggaaatg atgactgatt tacaatctca

55201 agaagcagaa gaagttaact agatgttctg ggaaggaatg agtgttccag gtagaagaaa

55261 ctccatgtgc aaagRggccc tagggcagga ggaacaaaac aagtaggagg aactgaaaga

55321 atgccagtgt gactggagta gggaggtcaa gggagagcat atggagcata ccggagtagg

55381 gaggtcaagg gagagcatgg tattggacga agtgataaga tggtttgacc attccccata

55441 cactgaagaa aagacaacat ttactcaatt attctttata gggcatcatt tattcaatca

55501 tgttttaaca tgtaaagcat tgggacattc agagatggtc tttgctcaga aagcttgctg

55561 atcagtgagt gaattgaggc attaaagaat tataattaat aatacaagat ggacaacaaa

55621 acatgtcatc agagaggtaa gggaaaagaa ctataagaac tcagagaatt gagaaattac

55681 ttcttgctgg gaacaataga ggaagacttt tttctttctt caagaagtat ttgatcctga

55741 gggagaaaag ggaacaagta ccataatcac agaagtggga aagagtacag gtgtagatat

55801 tagcaagttg cttataatgg ctgaagtact tgagcaaagt agcagaagat gagctagaca 55861 gaaccagatg aagcagggtt ttgaatgttt ggctaagaca tttagtctct acccagtagg 55921 gaaagcacac gttttatcaa aagaacaact taatcacaat tatattttgg agagattaat 55981 ctggcattat gggtagattg aataggacaa gagaccagta tctgggagag cagctaggaa 56041 acaatgacat ctacaaatgc ttgtctagaa gagcctgagc tgggatgcaa gaggcactag 56101 aagtaaaatg tggagtgtat taattatttt gcaagagctg ttgtaatgaa gcagcacaaa 56161 cggggtggct taaacaacag acatttattg tcccctagtt cgggaggcta gaagtctgaa 56221 atcaaggagt tggcagggtc atgctccctt tgaaacctgt agggcaaccc ttgcttgcct 56281 cttcctagct cctggtggtt tgtggtcatc tttggccttc ctgacttgca gatgcataaa 56341 tccattctct gccttcatca tcacatggtg ctctccctga gtgtctgtct ttgtgtgata 56401 gatggcttct gacaaggatg ccagtcatac tggattcggg gttcactctt gctgcaatat 56461 gactgcatct cagctcaacc aaacatgtct gcaatgaccc tatttccaaa ccagaacaca 56521 ttctgaggta ttgagaatta ggacctcaga acctcaatat cttttttggg ggacacaatc 56581 caacccataa cacctaggct gaagtcttat tggacagaag gacagaggga aggagctcag 56641 aggaggcccc agatgtgcgt gcattggctt ccctggccag ctagccctaa gctttcatgt 56701 tgcaggaagc cacctatact gtgtgagaag aggggcatct ctataaaggc tccagggctc 56761 tctcatgatg ttgccttctc atccaacacg tcctgaaatt ctaccaactc ccacagccgc 56821 atggggagga attgtcctca gataccctgg aggaaatgtc agggcaattt ctcacaattt 56881 tagacttggt ttttgccttt tgtgagaaag aaaaaagatg gcttttgcag tattttgtaa 56941 caactcgcat caatagccac tagatggcaa tcttcacaca tttccatgct ttctccgctt 57001 tcttcaaacc cgaatcctca aagcctggag gcaactcctc tctgcacagg gaatagaggt 57061 gagtgaggag tcccatttcc tgtgatcccc cacagacttt agtgcatgga agtctaaaaa 57121 aatggaagga agactgtctc tcacaatagt cctaatcagt tttagcaccg ttcatacctt 57181 ttagttgcat agtaaatagc atttcataaa tattcatgag tttgccgaat ttaaccaggg 57241 gaaaagcaag aactcttaac agtatgtggt cttgggtgta atttatgccc aagtatctct 57301 ggcatataaa agcggggact cttattccga gaggtctgtt tacttggtcg ttagcaaggg 57361 tgaaggagac acttgctgaa attagttttc cttctctcag aatcctaatt tgtgttattt 57421 atagtagcca gaaagcaaca gagaagcagc cctaatcttg tgatgatacg gagggagggg 57481 aaaacaagac cagagaattg taggtcttgg gcctgttcac acaggagcct aacttcgaaa 57541 tacaattgac tacatgcaaa gaccaagtta ccattgtttc cgtaaagatc tgttttaagt 57601 gcagtctaat ggtttgtata aagcatcttc actttttccc actcagacac tgagctagag 57661 gaaagaaaga acacaacact acaaaagtta gttaaaccag caatttgaaa agtagaaaat 57721 tccagaatca tgcatttctc attttgaaat aaaaaattat ttggttctat aacatacgta 57781 agcaatacat aaaagagtgt ttatctcgga gttagaagat gcttgtaatg ataagatgct 57841 cctgcttttt tcgagatggg accaagatgg gcctaagagg gtgggtgcac caactgtaat 57901 ttcttgtcta tgcttattat tcaccaaata tatgtatttt ttctgcgtgc atggttctat 57961 aatcagggaa ggagagaaca tttgtcaagc caggtgttcg ccataaacga tctcattaaa 58021 tatatttcac actttcagtc aggccctatt attattcccg ggtttggagg aagatctgaa 58081 gttttggaag ttgcacagct tgcgtagaca cacagtggtg gagctgggag tcaaatcctg 58141 gtatgttgct cccagagctg aaattcttct gtattctaga ctgccttcca tataagacta 58201 gaaaagatgt ccctgccttt gaggaggtgg tagggaagct acaagcccga gcacaggaaa 58261 agtaaaggcc tataatttac ttgtgggttt acctgtgact ggataacaag cgggccaaag 58321 aaagcagcca cctgtaattt tagaatccct cgggaagggg ccctattaac agggcataca 58381 attctgtcaa tccagtatga ttgggtgcag tgtcttcgaa gggcaaggcc aaattgcatt 58441 gcttacaatt tcacgcctca gtgttttact ctggttttgc ctggaggctt cttccgctac 58501 aggggttacc tcctccagga agcctgcttt gattccttct agctcttcca tgtgtgaatt 58561 atggccttgt ttgtgtcacg gcttacctta tgtcttcatt tattgctgcc cctgtggcgg 58621 tgtggaattg ggtatttttc acaagtctct cttgagctcc tatgagctct ctgcctgtga 58681 gctctgtatt catctctgca ttggctgcac ccagcatggg acatggtacg tgggaattca 58741 acacgtttgc taatggatgg atgggagaaa ggaagagaaa gaaaaggaag gaagggaagg 58801 agggagaaag agagaaagaa agggaaggaa tgaaggaaag gaaggaaaag aaagacaagg 58861 aagaaaaggg aaagaaagac aggaagaaag gaagcaaaag aaagaacgaa tgaatttgga 58921 aattgttctt gtagcaagac agatgaagat gaggtctttc tcagactggc ttccctttct 58981 tcaggcctaa ttttactcca tgtcataaaa gaatacatgg acaactttgt gcttcttcgg 59041 gttttcagaa catactacct ggataggttc catctgatct tatgcttggc ttaaatatta 59101 aacttaatta cttaggctat tctaaggaaa gcactcagct gtcaaggtgg ctcttgatat 59161 acacgagttt tcaatttaaa gcaatctaca gtcattaact ctccttgcct ccccataact 59221 ttcatcaggt tgaagagcag acagtgacat tttaaatgga aaagagaagg ggtaggaatg 59281 agaaaggggc aggagggtgt tgggatgtgg gctagctgtc aagagcagaa aatactgcat 59341 taaaactgcc ctcccccact gccctaacca ttccctttga gtttttaata tgaattaaag 59401 ataaactggt cagaaaaaac tgactggcat tgaagcttct caatgtgact tgtgggattc 59461 cctttggctt tcaatgtata gttgactaac ccttcccttt ccctttccaa gaagttaaca 59521 gaggaaagaa tggatctgct gtgagagaac tccattttct caataaatat taataggtaa 59581 acacatatta atatatcata tatgcatttt ggtggtcctt gggaatcaag tctgggtccc 59641 tggccaggga tggggagccc aggctggagg ccagtcagtc cactgtcctc ctctgtgccc 59701 cgggacccat atcttcaatt agttaggcca ggaatcctct taaacaatcc tacttgagaa 59761 tcacagcatc tctttgctgg ccatggtaca tggtccttta ttttaaggca aagaaacaag 59821 tttacagaag tgaagtgatt tgtcaaaggt catggaactg gttcgcagca gtgtcaggac 59881 aaatatgatt aacactatcc attcagcacc tactgtgtgt cagcactttg atgtatgtga 59941 tctctattct ttataccaag ccagaaacat aaaatatctc agttttgcag tgtagggaag 60001 tcagggaggt taagcaattt gtgttcatga cattttgatg tggatgtttt gataccatgg 60061 ttacttttac ttttgcacct ataccatgct ccttaaaaac aaccatttaa acttccattt 60121 ttgaaactac ctcataacga ggttaataga catcttcact ccatccgtgc cctatggatc 60181 catcttttag tgggtgaagg taaaggctgg gggaggatag gaaaggtcaa gaatggactg 60241 aaggtcagat ggaggctggt ggtttcagga atagggtgaa gcaaaagatg gggaaagttc 60301 agatatgggg tactgtttcc tgctgcgcac ttcccctgat aataaaatca ctggagagtt 60361 taatgattta cttttggact gtttcaaaat atgcttctcc ttttccctat cccatgcaat 60421 caaggtctct gggttccaag gttagagctt tcactctaat gtttggtttc ttgcttagta 60481 tgtgtttccc tcagtactca ataacaacgg aggagatccc tggattcagc aagaaaatct 60541 tgtaacaatc aagtaagata cgcattaaac tgaggctcag agaggttagg taattttctc 60601 aaggacatag aactgcctcc tcctagtgat gggagagcca gggtggtctg actcccaaga 60661 ccagggtcat ttaagtggac ttgattgtac ttctctctcc ttcccaacaa gtgcaagggc 60721 atggtctctc tccccgcagg ctggacccct gtctggaagt gcagaggctg cacactctca 60781 gacagttggg ttgcggccac ttttctgtgg ctgaccccat cccacattca tctgccatga 60841 gggacagtgc tggacattct tctgcccttc cagatcgact ctccatcttt cttcctcctg 60901 ctttgtgccc tgggaagcgg acctctctgc accatatcga caggctccct ggacctgagg 60961 tagaagatgc aagggtagga ggagaccaaa ctcaggtatt tattccctgg gtgtcttcca 61021 ggcaggtcac tgtcggatgg ctgtacccct ggtcaaatgg ccaaggctct tagaaagccc 61081 tctcctattt ctccctgggt tctaaaaata ggtctcttaa ttcttccctt tgaacctaga 61141 tgtggtaatg gctccctcac ttcacctgcc ctgggagact gtagtatctt aactggtttc 61201 cttaaatcat acttttgcaa acagtttctt taaaattctc ctttgatcat tggagtgttc 61261 tatctgctcc ccacca'agac cactgtttcc tctttcttcc tgactagttc catttggtaa 61321 aaagtgcatt attcaaacta tcatttaaag gaggcttgca aaaagaaaga agttatcatc 61381 tggatatttt agtaatccct tgaagaattt tagaggttgc taaactgtgg tcggctgcct 61441 tgctttcctg gtttgcaaat aaccgatgtc acaaaactct tgctctggag ctcttaaatt 61501 cacttgggga gttgaaaaaa attacatttt tttttttttt tttttttttt gctgagtcaa 61561 aagaaaacaa aggaaattta taccctgttt 'ccctaatggc actgattgac aatgagttca 61621 ctgtgggcag aggcacaggt gtgcagggag gaatgtgggg aaacatctga ggtcaattta 61681 aaattcctct ttgaaaattg ccagagtctg gtcggcagaa ttggacctgc aatttcctaa 61741 gtgactctgg agagcagata aagccctgga attcaggaaa aaaaaaaaag tgagtttatc 61801 ttccagagaa actgtggcta gatagctctg gggctacaaa gagatggaag gtgaataggt 61861 caaggttctc acattgggcc aagtattaat gtccaactgc tagaaatggg ggaaaaaggc 61921 acctagtaat tctattacta ggtcaccata taatttgttg tctaaactag aatttttttc 61981 agagtgaaag agagtgttta attgctctat agcaacagac ttacacagga actgtaacta 62041 gcaaaatggt atgtaaggta aaaagtaaac cgaaaaatgg aatcctcagg tgtcaggggc 62101 acctgttggg aggggaacca tccggagtat atacccggtt cttccacact gtgccttgca 62161 ctccaccccg tgagcaggga gaaggaggag ggccgtgtgt atgagaccat cattttattt 62221 acttcacaca agagccactg atgagatgaa gaagctaaag ctgagctgga ttaaggcact 62281 cgccaaaagt aagttggtgg ttgaagtagg cttcaaggat ggcttgtctg atttcaaagc 62341 taatcctggt tccccacact aacagagccc ggcagtgtat gacatttgaa gcaaaaggga 62401 tggcaagcga agcattaata attacgcttt ctccttctga ccttttctgg gagaaagtta 62461 agaaaaaaat agccgtttga gacttagtgt attgagcaat gggaaatcca gcaggcagag 62521 gctgtttgcg cagagaagac caagctcagt caatgaactg aagattggtt tcatttaatt 62581 acgttctatc tttaggttct gtgaggacaa tcctgaaatt ctgtcttagg ttgttcaaaa 62641 caaaaatgtc acacaagaat atgcattgct gtttaaatgt acccaggtaa gcatcattac 62701 aaaatagttt cctgttccat agaccaggat acaccataca gccgaccacc atccctgaga 62761 aagaagagct ctgtgtgtgt gtggccctcc tatctctaca cacactgatg ttaccagaac 62821 tctgttattt ctgtccctgg agttccagta aggacacaac tttcctccct tcttctcatt 62881 cctagttctc tttcaaattt agctgacctg gaatgtgggc ccaacattgc ctggacaagc 62941 acaacttgat cctgatatta gccttttatt caatgcttcc agctgactac atctagaatt 63001 tcccaactgc cgttcccctg aatttggcct gttaaaaact gcaatggaaa aaattttgct 63061 gtattttaga tgcatcatct caacagttta tggctttcac ttgtttttca aaacatcttt 63121 ttttttggtc tatacttgat tttgtttgaa attgctgata aatccatata gccctgtaac 63181 atatatggtg aaacttcata atccttaaga acatgggtaa ctgtgtggtt atcatatgta 63241 ggaatatgct caatatttga aaagcactat cgaacttcat ttttaccaca atcctataaa 63301 gtatatatga ctatctcccc agtttgtaga agctgagcct caaaatgctc aaataatatg 63361 tcctggtatc acagctggta gagctgggat tcaaatatag aactgtcttc aaagtccatg 63421 tttctagcca tcatactata ttgtatagaa tactgaatat tcatatttta ggataatatt 63481 aagggaagcc agaatcactg tatcaaagct gggaggactt gctttgcaga cgattaaatc 63541 aaaatacctc attgtgcaga tggctagtgg taggtgggat gagagaagaa gcagctttca 63601 aagtctgcag agtgagagta gaagtggttg gattcttatt caacatgtat tcttctgtct 63661 cccccttcct aagggaaccc tgcttttgtt taggccttca cgcttcgtga tttgaccctg 63721 tgtttcaagg gaggctgtgc aattgccaat gctggggaat gaatcatgat tggcctaatc 63781 catcatggtg aacccattcc ctcaccaatg ataggcttag acataggcag aagatataat

63841 tttggccaat gaaatatgag gaaatctaat ggagggtttc tggtaatatt tctttacttt

63901 gaaaagagcc atagaaagac acctgaagat atcctaatgt aggcagagga agaattagta

63961 cttctattat ttactattca ccatgctgtg cttccataaa tgacctctta ttcttagaac

64021 aaaatgggat ggcaggtttt atcataccca ttcatagatg aggagactca gacgtaagag

64081 cagttaagta attcagctgt taatagtaga gacaggattc aaatccagaa atgtatggct

64141 tcaaatgtat cttgttttag gttagttact tttactttgg aataaatttg acataggttt

64201 atgttaataa ttgtgttggt aagtctccaa tagtgtgttc gcttctgtgt gtccaggtag

64261 agttaggttc tgagtccgca gagctgtctg tccttaggtc ctcctccacc taggaatcat

64321 atggtccctt cagctgaagt cttggtcaga tgatcctctg aaatgacaat agcctagagg

64381 cttgtatgtg ataagggagg ttaaaatcat tcagtaatgc tggctttggg gacaggattg

64441 ggaggctcct tttctcttaa tgatttgctc tcaaattttt taaattaaaa atcttttttg

64501 taaagataga gtcacactgc atttcccagt ctggtcttga actcctgggc tcaaatgatc

64561 tgcctgcctt ggcctcccaa agcactggaa ttacaggcat gagccactgc acccagcctt

64621 gtcttgctgt caattctgaa tcacttgaag atgttgactt gagtcagcta tggtcacaac

64681 aaatgataga aaacaccaag tgattgttat ttggcacagg ttaggcaact ggtttgtttc

64741 cttccttggt tgaattaact caattgactg 'gtataggccc aagttcattt cttttaggaa

64801 aagMcacgca aatctctcta aataaagata aaaatgtcta ccttacaggg tcatagtgag

64861 aactacgctc tgggtacagt ttctattaca tggtaggaaa cagacatgct agctccctaa

64921 gtccccattt tcctctatgc ttccttcaaa tgtttgatca atataaaagt tatccagagg

64981 agaaatgttt ttgcatcttg taaacattgc taactctctt actcaatgcc atttttcaaa

65041 aagaattatt ttagaatcta gaactaaata taggttaact tcttcttttt ccaattaaaa

65101 aaatttccaa cccatcctat gtttcttttt gtcatggctt ccaggataat cagaagtaaa

65161 tttaattacc aagggcattg accagcttgc atccatctat ctatctatct atctatctat

65221 ctatctatct atctatctat ctatcatcta tctatctaca tttttatcct tatcatctag

65281 atgtctatca tctatctgta ttagttccct agggctgatg taacaaatgt aaaaaacaga

65341 tttcagttgg gagtttataa tataaaggat tcagctgagc aagtgtcaga ggatggagta

65401 tttgaggaag aggctggctt aaaacaacag aaatttagcc aggcgcggtg gctcatgcct

65461 gtaatcccag cactttggga ggccgaggcg ggcagatcat gaactcagga gatcaagacc

65521 atcctggcta acatggttaa accctgtctc cactaaaaac acaaaaaatt agccacgtgt

65581 ggtagtgggc acctgtagtc ccagctactc gggaggctga ggcaggagaa tggtgtgaac

65641 ctgggaggtg gagcttgcag tgagcctaga tcatgccact gcactccagc ctgggttaca

65701 gtgtgagagt ctgtctcaaa aaaaaaaaaa aaaccaacca accaaacaaa aaaaccagaa

65761 atgtactacc tcacagctta ggaggccaaa agtctgaaat caaggtgtca gcagggttag

65821 ttcctctgga ggctctgagg gacaacctgt tttatgcttc tctcctagct tctgaggatt'

65881 gctggcaatc tttagcattt ccttggcttg tagctgcatg ctccagtctt tgcctttgtt

65941 gtcacgtgga ctttttccct gtatgtctct ccacagggtc tccttataag gatacccata

66001 attgaattta gggcccactt gactacagta tggcctcctt ttaacttcac taactacatt

66061 ttcaaagacc ctatttccaa ataaggtcac attctgaagt tctaggtaga cattaatttt

66121 gggggtacgc tatttgtccc agtacactac caatttcaca cccgatgtat gcttttgcct

66181 tctgctcccc aatgttttct caggtatgct gttcaatttc tctaattgtt tattccacaa

66241 tcacttactg agtgctgcta tatatgagac attgacaata caattgtaaa caaaatcttt

66301 gtccctcacc aagctctcac agtttaatga agggacacac taaaacaaaa actcaattga

66361 gtatatgttt agaaatagta tgatttataa attatgacaa gtgctatgac ataatgtgag

66421 atatatgaga ttatgaaggg agatatgatt catattggtc tgggattatc agagtctgaa

66481 gaagggagat ctcagctgga agtttataat ataaaggatt cagctgagca agtgtcagag

66541 gatggagtat ttgaggaaga ggaggcaaca gcctgtgcag ggaagccaag aggaaagtgg

66601 ctgggatgag gctgggaggt gggcagggcc aggtcccaca gggcattgtg ggctatgcca

66661 atgtttcaga tttttgtccc attaacatgg gaggccactg caggcttcta agcagaagaa

66721 tgatctgcca catggaaaac aaatttgagg aggcaggagt gatagcagag aactagttag

66781 gagactttta tagtggtcca ggtgaagaat gatggcttgg actcgagtga caacagtgga

66841 gatgacaata aatgggcata ttcgaggcat attttataga aggaaaagac atggcttgtt

66901 gatgaatgtg gaagatgaga tgtgggaggc attaaggatc cttgccagtt tccagaatga

66961 gtaactagat ggccagagga gccattacca agatgtgagg cacaggagga aaaatagatt

67021 taggagggaa gatcaaggtt cagcttttga caacttaaat ttcagatgcc tggagaatat

67081 tcaagtggag atgtcaaata ggaaggtgga tacatggcct ggagctcaga agaagggtct

67141 gtgttgaaat acaactttgg gagttcttgg caaatagaga ctacttgaaa ccattattat

67201 tcactttagg tgggtttgtt ttttttttaa attgtcaggc tgaccttgtt caggtatatt

67261 tggctcctct tttaaatatc tgagcctgtg actctggtta taccttccag tctccaattt

67321 taatcatcca atttctgcct tattttatag gtttctttct aattacattg taaagtcagt

67381 gtactgcaat agaaagagat tctgattatt tgtgtgcctt agggaaacca ctgattatct

67441 ctgggtattc ttttcctaac tataaaagaa gggaattgat tgttttcagt ttcaaaaatc

67501 catgactctg taatctaaga agtactcgct aaggtatgtc tatttttcta catccacaaa

67561 ggctttatct ttaggtggta accactggta agttagcaat gttttgatta gattttgcag

67621 gatattttga agtacacatc atgtccatca attaacgatt aaatcaaaca ctgttcatgt

67681 caatctcaga tactattgct gtaattcaga acagcatttc ttctgcactt gtggatagag 67741 gttatgggga aaagtagaaa tttagatatt tactcatcaa aatagcatca catttaaatc 67801 taagacaaac ccacatccct gtaaattcct ataggaatgg acgctttttg gacaaagtaa 67861 aaaataatcc aaatattatg caagagtcta gtaaatgcaa taacctagat gatgaggcac 67921 aagtaatagc atttccttat gttctctgag gtacagctat acaacgtgtc accattttca 67981 acagtctttc catacctccg tgacagcaaa acttctcttg ccacagggaa ccaccctgta 68041 ccacttgtca tggagcatat ccataaaccc atgtgacttg tattgactga ttagctcgga 68101 tatgttggcg gtcaatggag agttgggtgg gaggccaatg ccgtatccta gaagaaaata 68161 caatctcaga tgagtttttt acacccttcc tgagagattg ccaccacagt acatatttgt 68221 gtgatactgc catcagacca aaaaaagggc gtgatgagtt ttcatcaact ttctttcaaa 68281 gcactcaaag acattcctag tcatgattac ccttaaatca gctgcatctc tgagtagatg 68341 aattgagttg gaaaaggaga ggaatgggct gtgcacagtg cattagtgaa aaattttaag 68401 atcttctgcc tttcccatta agacattcct tagaggcaat ctttgaggtc tttatcaggg 68461 ctaggatttc ctatctacct cttccagaac ccctcttctg aaccttaaat atacaaaatc 68521 agattaatct tagtctgtgg ttgatgacat tctcttatcg gtgttaatgc atgaccctct 68581 cttacttttt aaatttattt ttaatttttg aataatataa taaaaccatg tgaataaaca 68641 atacagtatg agaactaaaa tataaacagg aaYttataaa aatcaactta aattgtccaa 68701 aaataaataa ataagaagta atactaagtg ttaaagaaga tgaggatcaa taagattatt 68761 tatatattgc ttgctgtaat ataaactgaa aattgataca aacattttgg aaagcagttt 68821 ggtattattt tatatggttg aatattgaca tattttaaga ccagcaattc tgttcctgag 68881 tccattccca aagatctccg ccacaagcat atcaggagat acgtacaaaa atgttcttag 68941 aggaactgtt cataatagca aaaattggaa acaacccaaa tgttctttga caagagaatg 69001 agtaatgaaa ctgtggacta tttgcacaga tggaatatta cataatcaaa actatatgaa 69061 ctagaactag aggcaacaat atggatgatc cttagtaata tgccattgaa tgaaaaaggt 69121 cagtgtcaga agattacttg cagcatgaat tcattgtgta aatattaaaa cattcaaaac 69181 caaacaatat agttttagga atacatatat atgcatatat atgtgatact tttttttttt 69241 tttttttttt ttttttggag acagggtctt gctctgttgc ccaggctgga gtgccatggt 69301 gccatcatgg ctcactgcaa ccttgacctc ctgggctcaa gtgatcctcc cggctcagcc 69361 ccccaagtag ctggaaccac aggcacacac caccaccctg gctaattttt gtattttttg 69421 ttgagatagg gtctcaccgt gttgcccagg ctggtcttga actcctggag tcaaccagtc 69481 cactcacctc agcctctcaa agtgatggga ttacaggtat gagccacgtg cccagcctgt 69541 gataatactt attattttta acaaaaccaa ggataaaata aatgaaaggg tggtggtaat 69601 gcagggcaag ggaggcaggg gaaggaatga gggaggaaca taaaaatgga gttaatttgt 69661 tgtcagagtt ttattagtca gcttagactc tgtatcctca cactgtgtgg ctttacttgc 69721 tttccaaaat gttactatac tgttaatctc tttgctcagc catgtcaaag aagctaatta 69781 gctacatttt gttttagcta ttggacagaa tagtaaaaaa aaaaacccaa accctttttt 69841 tttttgcctt caacatgatt gaggaagagt gattaaaaat atagttcatt tttcatggat 69901 aaagactaaa agattgtcaa gcatccaaag atacttaatg gaaacaaata cctcctataa 69961 ttattctagc ttacaattca atttcaagag cactgatttt tgttcctttt tttttttttt 70021 ttttttgaga cagagtctcg atctcggctc actgcaagct ccgcctcctg ggttcacgcc 70081 attctcccgc ctcagcctct tgagtggctg ggactacagg cgcccgccac cacacccagc 70141 taattttttg tatttttagt agagatgggg tttcaccgtg ttagccagat ggtctcgatt 70201 tcctgacctc gtgatccacc tgcctcggcc tcccaaattg ctgggattac aggcatgaac 70261 cactgcgccc ggcctattta ttcaatcttt aagtctccaa gtgatacaca ttctggcgtg 70321 gtttcatgta gggattcatg cagaatagtg cttggggcac agtagagccc agtatgtcct 70381 agtacttatt attagaatcc aaggatgatt taaccaagct gtgtgccaca atctgttgct 70441 gttgttgaaa actattgacc cagggaggaa aaacacattg atattcggca aacctggcta 70501 attatcctaa ccatcaaccc actcctacca gatagtagca agtcctccta cactttgttc 70561 ttatatggcc cagttctccc ttatggtgcc tatctcagtt gtaatgaaat aataattatg 70621 ctgtgtcttg tttaatatct gtttcccctg tagagtatac attccattac agcagagacc 70681 atatccacct tggtcactgc taagtcctga ccacttaaca tggtgcctat ttactcaggg 70741 aatatttgtt gcatgaatga gtgagtgaat gaataaatga atgtgtgagt gagtcagtga 70801 atcagtgact attatacgct tgtgcctagt attgtgcatg atgtgcaaat aagtcctgaa 70861 taagtgtttg tgcagttgaa ttggcaacag cattcattat gtttctaaag aaagctgatt 70921 acttccttct aataaattac ccattatatt ttaaaatgtt atttaataat aacatcagca 70981 gaatcaaaag ctacccatcc aaactctttt gttttcagtc ctgcctttca aaccaaaact 71041 tctaggcata aaacaggcac tcaaaatagc tctttgaatg gaaaattcta atcatgcttt 71101 tgacgttgtc atcattttct tgacttccta ttgttaagca acaaataatg ttattagaaa 71161 aaaatacaat ccattaaaac tcagtttttt atgcgttatt tcatctcttt tattggttat 71221 acacacatct caagcctttt tcttttaaag aaaaagattg tgtatctgca ttaaaaaagg 71281 tattctcact tataggtggg agttgaacaa tgagatcaca tggacacagg aaggggaata 71341 tcacactctg gggactgtgg tggggtgggg ggagggggga gggatagcat tgggagatat 71401 acctaatgct agatgacgag ttagtgggtg cagtgcacca gcacggcaca tgtatacata 71461 tgaaactaac ctgcacaatg tgcacatgta ccctaaaact taaagtataa aaaaaaaaaa 71521 aaaaaaaagg aacaaaaggg ccgggcgcag tggctcacgc cagtaatctc ggcactttgg 71581 gaggccaagg tggccggatc acgagatcag gagatggaga ccatcctgac taacacggtg 71641 aaaccccgtc tctactaaaa atacaaaaaa ttagccgggc gtggtggcgg gcgcctgtag 71701 tcgcagctac tcgggaggct gaggcaggag aatggcgtga acccgggaag cggagcttgc 71761 agtgagccga gattgcgcca ctgcagtccg cagtccggca tgggcgacag agcgagactc 71821 cgtctaaaaa aaaaaaaaaa aaaaaagaaa attcaaagga acaagagatt ggtaccagag 71881 gagaggatga aagatggcat cttgaattgg ttcttgattg tgatattttt ggtagataag 71941 acaaaagtat atgataagaa agttttaaat tcttaacttc atacttatga taaatctaca 72001 tattctaaga atagaatttt ggcactacaa caaaagtgtt aagattccct aatgaaaaag 72061 ctatgttgaa gtttcagaga catttataaa aaatgttaca caagaaataa taaatattaa 72121 atcactccac tcgatcatgt ctaggttaat ttgcagttgc taaaaacaga ttactatccc 72181 tttaaaattt ctgtttaaat acatgtattg aatattgata ttttatttta ttttatttta 72241 tttatttatt ttgtgtgtgt gtgtgtgttt ttcttttatt attatactta aagttttagg 72301 gtacatgtgc acattgtgca ggttagttac atatgtagac atgtgccacg ctggtgcgct 72361 gcacccacta ctcgtcatct agcattaggt atatctccca atgttatccc tcccccctcc 72421 cccaacccca caacagtccc cagagtgtga tgttcccctt cctgtgtcca tgtgatctca 72481 ttgttcaatt cccacctatg agtgagaata tgcggtgttt ggttttttgt tcttgcaata 72541 gtttactgag aatgatgatt tccaatttca tccatgtccc tacaaaggac atgaactcat 72601 cattttttat ggctgcatag tattccatgg tgtatatgtg ccacatttaa atcaattcaa 72661 gatggattaa agacttaaac attagaccta aaaccataaa aaccctagaa gaaaacctag 72721 gcaataccat tcaggacata ggcatgggca aggacttcat gtctaaaaca ccaaaagcaa 72781 tggcaacaaa agacaaaatt gacaaatggg atctaattaa actaaagagc ttctgtacag 72841 caaaagaaac taccatcaga gtgacagagt gaacaggcaa cctacaaaat gggagaaaat 72901 ttttgcaacc tactcatctg acaaagggct aatatccagc atctacaatg aactcaaaca 72961 aatttacaag aaaaaaacaa acaaccccat caaaaagtgg gcaaaggaca tgaacagaca 73021 cttctgaaaa gaagacattt atgcagccaa aaaacacatg aaaaaatgct caccatcact 73081 ggccatcaga gaaatgcaaa tcaaaaccac aatgacatac catctcacac cagttagaat 73141 ggcaatcatt aaaaagtcag gaaacaacag gtgctggaga ggatgtggag aaataggaac 73201 acttttatat tgatatttta atgatttcta gcaataataa tcatttttag ctaatgaaaa 73261 caaactatgc atatggaatg atgggaaaaa taggaaaata aattatgtga tgatgagaag 73321 acttatttgt taaaagagat aaaaatccat tttattcaaa aacataaaat aaaaccttga 73381 gggttttatt tctgtcccca tttatagttg cttttcaaat ttgctagtgt tcattggtca 73441 aagaattctc atttttaaat tgctgactca actgagcagc ctgagttgct ttcattatta 73501 ctagaaatgt ggctttgcaa taaagacagg gttgactatt ttgtggttga tgaatgaagc 73561 aaaatggaat ccttcaactc taaagatgaa ggcatcaggc atcctggaaa ttggatacag 73621 cttaatggcc caagagaaca gttttcagaa tagaatcctg atcttttcac catggataaa 73681 tcagctttat taagctaaga gtggtggaaa tatattttag ctagcaaatg tatagttaga 73741 aattcataga ctaaaagaat cttccgaaat gtggttggaa aagagatgtt ttgaaaatag 73801 catctcagat agggttaaaa aggcttcagg gtgaaagatt tattcaattt tgcagtctgt 73861 ccttggaata ccatatttag ctactctggg ataatggttg agaacatatt gtaatggtcc 73921 caactataaa ggtactataa aatgggtttc ccttagcctc agcatatcaa agtggggaga 73981 gaaatgtgtg ggagaagttg agacttagga agactatcct ggaagaattt tacagttaat 74041 tggtctcaat gcattaatca atatactata taataataat ttgttgagca cttcttatgt 74101 gccaaacaag ttcctacagt acatgcttta tatgtattac ttaatcctca caacaattct 74161 atcataaatt tcctattcat ctccccatta tgcaggtgag gaacctgaag agtagattag 74221 ataacttgcc agttaataac agcaatttta tcctaaccca agtactcaga ctccagagcc 74281 agtgttccaa gcattgcatt aaataattat tggaaagcaa gtaaaagaac aaactcataa 74341 acaggcaaag gtctttggca gaaagatcac acatcattat tgtgcagtta cgttactctt 74401 tctccttgtt tgagctttat tgtcagctaa ctccaatgca caaattggag acacgtattc 74461 atttatctca acactttttt ttctcccctg cacacaatat gtatttgtgc ccctggttta 74521 tggtttttaa ttcgaccaaa gactttccac atgctttcgc atccttaata gttttggttt 74581 gctttgctat atactgcgta ccgatgagta ctcatgaaag ggtttcaaac tcagtgtgga 74641 gccactgtcc cttatttgcc ttatttttcc cttttaagtc aaaataaatg cagaatggtg 74701 aagtttggag ggatagttaa tagttatctt agtctgctca ggcttctata acaaaatatc 74761 atagactggg agacttaaaa acaaaagaaa ttggtttctt ataggtctgg aggctgggaa 74821 gtccaagatc agggcaatgg tagatttggt gcctggtgag ggcctgcttt ctggttcata 74881 gatggtgcca tgtagctagg tcctcacatg ctgaaaaggg tgaatgagct tcgttgagcc 74941 tatttcgtag gggcactaat tccattttat tagggtggaa acttcatgac ctaataccat 75001 caccctgggg attaggtttc aacatatgaa tctgggggga ggcacaaaca ttcagaccac 75061 agcagtagtt acactgagtg tcacacatag agtactgagt gtgttactac tatatgcagt 75121 gacagtacat tcagcatgaa ggaatcattg cactctgttt tctctcctaa gtacatttaa 75181 acatttggga aagtataagt acaagctatt aactacctaa gtgagtgaat taggtaccta 75241 tttcaaacct aattagttat ttaataggta atacatcact tattacatta atgttatatg 75301 cctagcattg tactaggccc tgtgaaaggt tatgggtagg catataaaac attcctgtaa 75361 actaaatgac caagtattgc tcatacaccg ctttgatgat tttttatacc tatacagtct 75421 aacttaataa taaagctcac attttaaaaa gttcaagaaa cttaaatgtt gtcaaaggat 75481 agcatatatt tttaacaatt tgagagaaat attttctcaa aaattcatga aattatttct 75541 ctcaattaaa ttgttaaaaa tatatgctat cctctaataa catttaagtt tcttgaactt 75601 attaaaatgt gagctttatt atttagactg taggtggctc acgcctgtaa tcccagcact 75661 ttgggaggcc gaggtgggag gatcacttga ggccaggagt ttgagaccag cctggccaac 75721 atggtgaaat cctgtctcta ctaaaactac aaaaattagc ggggtgtggt ggtgggcacc 75781 tgtaatccca gctacccggg aggctgaggc atgagaatcg cttgaacctg ggaggcagag 75841 gttgcagtga gctgagattg agccactgca ctccagcctg gatgatagag tgagactcag 75901 tctcaaaaaa aaaaaaaaca atttgtgaaa ttcatatttt taagaaaagt agcaatcaag 75961 actttgacta gtatttctac cacattgttt cgtgtaattt atacgtatcc ttttgtattt 76021 tactgagtta tgtttttggg gtatgaactt attgtcagaa gtagaattga attaattttc 76081 tgatgtgtac cccatccatt tggagaataa cctcacaatg ataacaatat tctctcaatt 76141 aaaacctgca gtatttctac tctcttgcag ggagggcttt tccatgcacc attttgtgct 76201 catctccttt gaaaacaatg tgatgtctag agatgttggg aactgcaaga cactaagtct 76261 caggaacaca gatggaaatg taaacaggaa accagtgggg agttaattgc gtggcatctg 76321 gcactagggt ccagcagagg caaacaagcc atcctaccac tgtcttttga caagatagag 76381 ttgtcccctg aagataaagg tggaaaatgg agcccctcat tcttgtgtcc tctacccatg 76441 attcattgtt agtagctcct aatggcagaa gggatctcag ttacccagtg catctaggac 76501 agaaataaaa tgtaacatcc ccagatgcca caaaaaagga gaaatttttc attgttacat 76561 taaaatggga ttatatactg aatgttgttt atttttctag ctttttcttt ttctcccttt 76621 gctatctaag acggtagtct taatagaaga ccactactgc taattgcctc tctttctgag 76681 ttccatccct gcttcaggtg ggggtgactt tgcctggaga ggggactgat ttctgctagg 76741 agaagatgtg gagaaatagc atcagctgta acattctcat ttatcatgaa aacaaagaca 76801 gaggtaaaca ttttaatctg ctgatatatt tagaggagac agagactaac tgtggttggg 76861 aaattgaaat cagaatagtc ttgatatcct agttaacata caggaaagtt cagatttctg 76921 gaaatagcag ttgggcaccc ccacgggatt gttttaagcc aaagtgtttt ctgtcaagtg 76981 agcatggctg tctcgagagc cagcatgcac tatcaggaag ggaagctggg aattgggaga 77041 agtgaaattt gctggttcaa actatcagct ccatatatca accgtcattc agaatgaaag 77101 gagctaccga caaagcaatc tttctttggt tctgaagttt gattgattgg gagatcacat 77161 tagaaggaaa aatttgctgc cagtggagaa aaagacctga gatcccaaac aaggatccca 77221 aggttttgtt tgggacctta aagggcatta aactatagaa tgagtttttt tttctactta 77281 ttttccaacc agtggaataa tacttattta agaaccagga gctttagatt tcagtcccag 77341 tattatcatc taattgtaca attatgaaaa tgttatgtaa tgtccctggg ctttcttgtt 77401 tatcaaatga gtagattgca ttagatcaat attggggccc tcccagttgt aaaatgtaat 77461 cattctagtt tttctgtcag atttgctaga gtatttggct gttagaaaat acagatttcc 77521 ctgaattttg gaaggctgag gcaggaggat cacttgaggc caggagttgg agacaagctt 77581 gggcaacata gcacatagca acaccctgcc actaaacaca cacacacaca cacacacaca 77641 caatacagat taaattaaaa tttattacac tgtgccacca ctcccagata tctgaaacaa 77701 catcatatgg gtaacaatga tttttccccc taaaaattgg ataagtaaat atttgttgaa 77761 taggtgaaaa ataaattcct aacttcagca acttaatagc taagtgctta tgagttgaaa 77821 atgaaaacga gggaagatga atagctcttt gcttctgact ttggcatttg tgactttcta 77881 ggttggcaaa ctgagcacat cctgagtaaa agtgaatcaa gagtgactga ttaatacctt 77941 ctatggcaaa tggcttcccc acagtgagaa gtttgcagtc agcatctatt gacacttcat 78001 aatccagaag ggctttgtcc atgatgaagg cgtctagttt ctctggatca ttcctatatt 78061 taagaccaga ggagaaaagt gaaaatgatt cattaatggg aaggaagcat gaaggctgac 78121 agccggcttt tgtttagggg acagaacccg aacactaagg gccgcacaag ctacctaggt 78181 gctgacttag ctgtcttggc ttctcactga tgtctagact acagaccagg ggagacaggc 78241 actcttataa gacagcatga catctttcca atgagtttat ctaccagctc^' ctttaattac 78301 ttctaaatcc atcagtaaag ccagagccac tctgaattga ataggaagcg catagagaat 78361 gtttattctt attacactgt tagagggact tcttgttgtt aggcattgca ttcattgttc 78421 tctatacctt ttatcactca gaatgactgt gatataacag atgaggaaat tgaggctcag 78481 aggattgaag taacttaaac caggttacac agctagtaag tgttgggact aggttcagat 78541 gaagggtgag tctcagcata ggctgagctt ccacctacaa agagggcaag gaaggagaag 78601 ttttaaaagg aaataactgt ctaaaataca tgcaacgatt tctttgtttt cagccacttc 78661 caattctttt tggaaaggtg aaagacatac atccatttaa gaaaggattt tctatgagga 78721 acagtttcag aaaagctctt agtctaattt gcttttattg tgactatgtc ctgagcccat 78781 ccctggatat tgttaccatg gaaatggact atcattcctt ttttaaaaat tttttttatt 78841 tttttatttt attattatta tactttaagt tttagggtac atgtgcacaa tgtgcaggtt 78901 agttacatat gtatacatgt gccatgctgg tgtgctgcac ccattaactc gtcatttagc 78961 attaggtata tctcctaatg ctatccttcc cccctccccc caccccacaa cagtccccag 79021 agtgtgatgt tccccttcct gtgtccatgt gttctcattg ttcagttccc acctatgagt 79081 gagaagatgt ggtgtttggt tttttgtcct tgcgatagtt tactgagaat gatgatttcc 79141 aatttcatcc atgtccctac agaggacatg aactcatcat tttttatggc tgcatagtat 79201 tccatggtgt atatgtgcca cattttctta atccagtcta tcgttgttgg acatttgggt 79261 tggttccaag tctttgctat tgtgaatagt gccacaataa acatacatgt gcatgtgtct 79321 ttatagcagc atgatttata gttctttggg tatataccca gtaatgggat ggctgggtca 79381 aatggtattt ctagttctag atccctgagg aatggccaca ctgacttcca caatggttgg 79441 actagtaatg caaatcaaaa ccacaatgag ataccatctc acagcagtta gaatggcaat 79501 cattaaaaag tctggactat cattcttatt ggctaggtgg tgtcacctgg agccaggggt 79561 ggggttcacc tcatataaat cagtgagagt agaagaggga tgaagaaatg caggatgctg 79621 tgaccaaaaa gagggaatgg attctgtgaa gaccagaaaa gcaaccattt tgtgcactat

79681 attatctccc cagttaaagt gtaagtttct tgggaaccag aactctgtat tacacttctt

79741 tctatctcat gcgatgacta cctcagttcc tttttattgt gtaggtgtag gtatttattt

79801 tttaaaaata aaaatattta ttaatttgaa aaaaaagaaa ggattttcta cccttagagt

79861 tgtccaaaca gctttgcaaa aagaataact cttttctatc ccttctgggc tcagtccttc

79921 ctctcttaga tccagtggtg aggctgttct aatttaacac agtgtggctt ctaaacagag

79981 gagaatatga ctagaattca tagaaaatca aaaagagaaa gatatcccta gacacccaga

80041 agattcatca gggcaggaaa cacatcctta cacgaatggc tttgtctggg tcatgtatag

80101 acacatagtt ggcaggtcag cttccctttt tggtaccaat gaccgttgct ttcttatcct

80161 actcttcaaa taagtgaaat aaccaattta aaatgcatcc ccttttcaaa ggggtatcag

80221 atttaagtta caatgaggcc caaatttaac tttaaccaaa atgaagcatc tcccagctct

80281 acagtaatgg gaagctttag aaagtgttgg ggatgtggat tgtctcctag aagttgataa

80341 ggaatcttaa tggaatcctg gcaataaaat aaaaattgag ctgaaagctg tttctccaat

80401 caaagttcga ctgccacagt accataatgt accttgacag ctacgtagcM acaagttatc

80461 acttgccaat attccacaaa tatttgtggt agcaatatga caataaaaaa gatgaggttc

80521 atttcagttt tttaaaacca gtaattcatg aagcctaatg tctctgggat ccttccttaa

80581 ataactactc ttgattttgg actgcaaagt gcagatagct atgataaatt tcagttacgt

80641 gaaaaggcga aaagcagtca gctctcagac tccattggga ccctgagtca ctggtgagga

80701 aatggccaag tgggatccag ttacaagtag cttctagatt ggctgaatca ctgttgtggt

80761 tcacagggcc cccaatggtt atttctatta tagaatcatg ccctgtcttt tcttaagcat

80821 tatttaaaaa tacatatcac acatcacaag aaaaccagtc acatattaac ataataaaag

80881 gaataagcat tttagtagga gttaattttt tggaaaactg ttaatgagaa agcagggccc

80941 tgagagagca gaattaagtc caggagaatt ttgatgggag agggaaagga caggttcaat

81001 atgtagaaaa gttccttgca caggcaatgc taggggttgt gccttgtagg tcagagctct

81061 gggatgccag ggaggtaaca tgaagactgt ggttgcggga agtggtggct gagggcacag

81121 gaaatgacta ggctgaaagt ggagagttaa ggcccagaga gaagtggtga gagggcatta

81181 atgataagct ctgcctagat Kccaatttca cctcaatcag tgaattgcct ggggagcttg

81241 ttaaaatgaa gattctgatg cagtaagttt gggatgaggc tggagttgct gcatttctaa

81301 ctagctttca gatactaact gcaacataga tgttgctgga acatggacta ttctgcaaac

81361 atcaaggacc tactctttca tcatcgttcc cagactagtc tgaagcagca gttggattcc

81421 agagacctgg tcctagtcct gactctgcca cttgctagtt tattaccaag gaaaattgac

81481 ttgtcttggg ccttcatctg tggccgcttt cctgaagatt gcttcccttc aggctagggc

81541 agggccagtg ctgggcacgt gggccttctc aggtaaagct cctgagatac gtgaatgccc

81601 tgagtggagt ggaactgctg gggactgcag cagtagctca tctcatcctt tttcacactg

81661 tcagcagagc ctagtttgtc tgctatttct attgagctgg aagccattgc taccctgaca

81721 tcttattctt tctctcaacc ataaattcgc ctgaagaaga gaatacacaa gaagatctgg

81781 gaggtaaagg gactctaaac ttcatgtcag agagagactg taatgtgttg atgttcttgc

81841 aaaattaaaa gtggcatttc ataatactta cacatcatgt ataattttgc aaatatgaga

81901 gaacaaggct ttttctctaa gctatagtta aaagtccata aaatttttta agtggcatgt

81961 ttctaaagtt gttgagaaag acaaaaccct tatgttccat gaaattattt atttatttct

82021 attctttctt aaaaaagaat ttgaggtggc agatcctgct gtccattggg gagattattg

82081 atgctgacca tggagaaacc agtttcctga tgctgcacaa ttctaggaat tggaggtgtg

82141 gatgtctgtt attatcttga ttccatcgag caggagggag aggactactc accctcatgt

82201 cttcctgttt ttcaggaacc attctttccc ttttctcagg aagactagac agaacagacc

82261 catcactgca ctgtctgcct ttgtattcaa cttcattgaa ttacaggctc tgataatctg

82321 ccatggcagt gtgatttctc atgattgctt ctcataaatt ctgatgagaa gaatgcaggc

82381 atgggaatca ttgtcttcta tcttatttcc tttctacagg aaatctctaa gataaactcc

82441 atttcctcat ggcaagagga ggcattccat gggtttagag atatattcac tgggaaggaa

82501 aacgttgcct tgggacactt tatcctctgg ccMtattccc tgtgtgtttg actatttcag

82561 caccattgta ttctcaagtg atgtaaagcc aacatttact tcctccacca tctgctatgc

82621 taatggcccc actgactctt tgaacaaagc tactaccaac ttgagactat gcaggtcaca

82681 agtaatctag gtcacataat taaatacaca ctatttcaca ccatctcctg ggatctcaca

82741 cagtgtaaag tattacttaa Yacaacgtgg gtatattcat ctgtcatttt cagaaactaa

82801 catatactgc gtcagtagct aaattacttc tcttcagtga gaatttttct ttggatccaa

82861 gaggttgaca ctcacttcag atactccact ccatcagggg tggctggaac attgtacctt

82921 ctcatatatt catgcatctc tgggaaactt tgtctcacat aatcttcagc actgctttct

82981 cggacagttc caaagcggaa tccttgggaa ggatgatgta actatgaggg agaaaaagaa

83041 atggcttaaa taaaaattat tcttagaagt gttttttaac atttttttca taattctttg

83101 aaacttaata ataattcgga acttttctaa cccccacagg cagaaacatg tacatagaaa

83161 tgtgcagaca tggctacatg ctttttacat cagaaattgc tctatcttta gaagcaaaca

83221 gatggaaacg acaaacaaaa aatacaaaac aatttttttt gctttatatt ggaacctatt

83281 agaattcttt agaagccatg caaattggca tgtagaatta gtctcattat tgtaaactgc

83341 atatcagaca aagtgtacat tcataataaa gattatgata ctccttggtt agaataacat

83401 aaaggccaag ttaaaacctt acatcctgag attacaataa acctgcgcta atgctgtgac

83461 tacatcactt ttgtgtttag ccacctttag gctatattac attttgttta ttgaatttat

83521 ttttagtgtt ttcataaaat gttctcatct aggagggaga taatacagag tatttttttt 83581 aataattagg tttttaagtt gtttacccta aaaatgatta agaactcact gaatatggtg 83641 acaaataaca tatatttgaa gatgaattag ttttgacaca cagtaaaggt gtaacaataa 83701 ggtaatagtt aaataaatta tatggtatat tcttatagag tgtaatgcaa catataaatc 83761 atgtttgtaa agtatgtttc ataaaacaag gcaaatgctc atatggcaag tggaaaaaag 83821 ctttcatatg gtatgatcaa aacaaaacat gtatacattt atttaaatgc catgatttcc 83881 catatatatt atacacacac acacatacgc acatgcacac acaccttgga agaaaacaca 83941 ttggtgttga atttacagat gtatttttta tttacagatt atctgcagaa acacttacca 84001 tgtttacaag tataaaaaat attttaaaat cagcaaaatc gttcatttat tcaacactta 84061 ttgaaggcct actctgtaga gYtctcaaag ttactagggt gacaaagata aatacctgca 84121 accactgcca tataggaact cttaaaacct gttgttcatt gtatttcttt ggtattccac 84181 tgttaagtaa gtaatatagc ttgctctaag tttaatgtaa ttgttccatg cactgaacaa 84241 attctaatgt tttatgccag cataacctta atgccacatc aacaataata acaatactta 84301 acatttatta aacacttatt atgcgccaaa caagatactt agagctttac atacattatc 84361 gtgctgaatc ctcataatag cttcgtgaag agggcactgt tgttacttcc tcttagggat 84421 gagtaaactg aagctcagag aagtgaagta atgggcataa ggtcatgcag ttgtaagtag 84481 cagggactgg ctcagaaccc atgtctatct tatttcaaag catgtgctat tatctactac 84541 atcatcttgc attctagctc atgacaacaa ctgaagcgat gatgtttatt aggaggaact 84601 caccaggctt ttaaaaatat tatccttatg ccttgaaccc ccggggctgt tctcatagta 84661 gcaaattgca gtcgtatggc ttgcgcaagg cacatttatc agcattgtct gYccaacatc 84721 tattaatttt tcaagaccta ggtcaaattt ttctatgtaa agtcttttgt cttgtgtagc 84781 ttcaccctcc tacccagaac aacaacaatg aaaaaactac ttatttatct gtgctgatat 84841 agtatcttgt acatataaaa tatgtaggca aagacctagg tgaaaatttt ctatgtgaag 84901 cctttggtct tgtctagctt caccctccta cccaaaacaa caacaataga gaaacataac 84961 tacttattta tctgtgctga tatagtagct tgtacatata aaatatgtag gcaaatattt 85021 atttaagtaa tctttgacct ttccgtgcat tatctccttt gatcctacca agaaatgtga 85081 ggtagatatg tctatcatct ttttacataa agaaactgaa gattagaaag tgtgtcattt 85141 gtccaaggtc acagagctag taattgtacc tgggattgga attcagcctg atcaaagaca 85201 ttcagctttt gacaactgtg taacattgct tctgatacta tatcatactg actccctctg 85261 tctggatttg; ctacttgtat gccagacggt aagctaaggg cttttaaaat tttcacaata 85321 atcttacaag atagatgtta ttttcttatt ttgcagatta aaacactgag gcttggatag 85381 ttaaagtaac accaacttct cacaactagg aattaacaag cttcagccca tcctattttc 85441 tgtaacttgc agaccaactt tcatttgttt gtgtaataca gttacctatc acgacctttg 85501 gcaccttgca ggtagtctat atctgtttgt caagttaatt cattttatct agtctatttt 85561 tctatcctgc tttatccatt taacttatat gcattcttct gctctcagtt cagtaattac 85621 ttccctaact tattgtgtag gccagattct tttttcgtaa gcccttacag tacatatacc 85681 tatcttttgt agaatctatc acagttgcag ttttaaattt aattatgtaa tcatgtgatt 85741 agcgtctaga ctctcagttt cttcactaac tggaagctcc atgtaaacaa gaataatgtt 85801 aattttaatt tatccttgta tttctaatgc ctttcatttt gtagttgctc aagaaaatac 85861 ttgatgagta attaattgat aactgttctt tgaacttaga ggaaggtgac agctttgtca 85921 tctcacttag cacaaactaa gctaacagta tagcttacaa ctcaagcttt ctaaacaaac 85981 cctctcttta aggtaaaagg gctgtagaat cattaattaa aatacctttc tctcatatag 86041 aaacagaatt ccttccagaa atacattctt tacattatgt tgtgataata cttttatggt 86101 ctatgaccag gatttttagg gaaatcctgc ttttctgggt ctcattttct tttctgaatg 86161 caccagcaca tcgttccttt ccaaagcatg gaaggaatca gggaaccagc agacccaggc 86221 tcagaattct gctggaggac tgtctctttg tgtttttcct ttgcatgact ttctgttgta 86281 tttgctcatc agctcccata tctgtcttat tggctctgtg aaggcaaagg ttctgaggtt 86341 ctgagaattg aaagttcctt caaggattag caaataagca gactccagga gagaaagcat 86401 cttattagcc tgacagggac ctcactctaa catggagatg ttttgcaaac actgccactg 86461 ctcttatttg agtcaccatc atttctgtca tccacatatt ccctttcttc ctttctgatc 86521 cactcagaga aattttagaa ttcagatctg atcatgtccc tcacttgctt aatgcccatc 86581 aatggctccc ccatggccct tgggatgaag tccaaactcc tcacatggcc tctaaggttc 86641 agcatgtttg gctcctgcct tccttttcct agccttgtcg tcctgctctc cccctggcct 86701 tccaagcttt ggccagttct ctcatttcca aaacaaacat tttgcttggt cagagctctt 86761 gcatatagtc ttcagtcggc ctgggacact ttttcctcat ccctacttct ttgtctagct 86821 aactcttaaa tgtcacttcc tgaggaaaac cttcactgac ccctagacct gtaacaccct 86881 cccattatac ctacagtttc. acatagcact gacaacactt gggattattt ttataatttg 86941 ccttccctgc tagattgtaa gtttccatga ggatggtgcc catagtgatc tcattcatgt 87001 ggttgtaagt cttcaacaaa tgttagctgc tattattatt atcattgtta tgcaacaagc 87061 acagggctta gcacatagta tatgcttgat aaataatgac ataataaatg aattgtcatc 87121 attattaaga gaatgaatga aattctctta ggttagatac attaaaaatt tggtggtttt 87181 tatcacacct cctgctgtct tttttctcct taaaactaat tttttccttt gttactttaa 87241 ttcRttcaaa atgatatatt cttctttctt tctctgtgtg agattatatt gaaaaataac 87301 catgggctac tcagcagtca cagaataata gaatcagaaa agggatctaa gaagctattg 87361 atgcaaccca gtgggccagg atggtctacc ctgtgtgtaa ttcagacagc cagggatgtc 87421 agaaagcctg catcaaggaa aaaggataaa agtgtacaaa cagcttaagc atttgagctg 87481 cattacaacc atcaccaaga agtcccagtg agagaagcat ttctttaaag tttcagctaa 87541 atacctcacc agctcttccg attctgttta tatttgcatc aaccttttta ggccttgggg 87601 aaatatctaa ggttaaactg tctatttgta tgtgaattgt tcagtattaa tggaatactg 87661 acctctacac agagtaccta catggagaat aatcagacat tcccgagaaa gcagagaaat 87721 ggctcaaaac aaaatgaggc gaactcggga aataatcaag ttgctatatc caaggtagat 87781 gtaatgttgc agattaaaaa ataatcccag tgctgagtat actcatttaa ggtcttcatc 87841 tgtacccatc tgagattagt acttaattca tcagtgaaat gtagtcactg gacctggtat 87901 tatgttcttt ggagttgggt ggaaagggct attcctaact tgcctagtgg aataggatat 87961 agtatgtatt gaattcccag ctcccttcta ctgcattact ttatccactt ataacctgtg 88021 gatgctatag tatcaagtgg tctcagggat ggaaggggct ttgcaagtct aatcatccac 88081 taatgtctga gtcatcagtg gacgattagc aggggtccca aacccctggg ccatggacag 88141 gtaatggtcc gtggtctggt ggaaccaggt gacacagcca tgggcaagtg agcattatgg 88201 cctgagctct gcctcctgta aggtcagcag cggcatgata ttctcatagg agcatgaacc 88261 ctattgtgaa ctgcaaatgt gagagatcta ggttgcacat cccttacaag aatctaatga 88321 taaatgtaat atacttggat tatctccaaa ccattaccac ccacccccaa cccatccatg 88381 aaaaaattgt ccacaaaatc ggtccctggt gccaaaaagg ttggggactg ctgctttata 88441 gcaaggttaa atgtactgac taaggtttct tcaaaatgta gattccaatt cagtaggtct 88501 aggtggaagc ttaagactct gcaccaacaa actgctaatt gatgcaaatg tcatggttta 88561 tggaccaggc tttgagtagc aagattttac ttataatatt cctatgaagt gcctgttacg 88621 ctgttacttc tctgcttgat catctccagt gacaagaaaa ttactcctcc tggccgggca 88681 tggtggttta cgcctgtaat cccagcactt tgggaggccg aggcgggtgg atcacgaggt 88741 caggagatcg agaccatcct ggctaacacg gtgaaaccct gtctctacta aaaatacaaa 88801 aagttagttg ggaatggtgg cgggtgcctg tagtcccagg tattcgggag gctgaggcag 88861 gggaatggcg tgaacccggg aggcggagct tgcagtgagc cgagatcgcg ccactgcact 88921 ccagcctggg tgacagagtg agactccgtc tcaaaaaaaa aaaaaaaaaa aagaaaatta 88981 ctccttttga ggcatagctt ctgtaaatga aaggtgactt ttgtctccac acaaccaatt 89041 gattctatct gaatatataa taataataaa ataacagcta atattttata atatttatta 89101 tatgctaata aattcatatc taatgagatt gctactttta ttatttatta ttacatatga 89161 ggagctgtga ttcggggaga ttaaacacct tgtctaagat gatcagaaag tgataaagtt 89221 ggatttaaaa ccaaccctga cttgaagttc ttaacatacc cttatctagc actacattct 89281 gcatttatag acttgtatta ttgtccaagt cttgtgaaaa tccaactaat atatacctat 89341 ccaactaata aataccaatt aatatatacc tatttgtgct gcaacttcag aatcaattta 89401 ttatagttgt gatcatataa tttatagtgc aaactgggac agttctctaa aagggggaca 89461 ctattgatga tcacacaagg acaaaagaca cactcggact atcctggaaa acaagtatgt 89521 atgtttaccc tagttattac tcatgctctg aatattagaa tacagaaaaa caatgccaaa 89581 aagaatgttg ctgaggtcca ccctgtattt tttctaatgt gaattactaa gtacatctta 89641 tgctgcagtt ctttttcatg ttattcctat tttcttccac agaagctgct tcctccattt 89701 aaatttaagc agtttgctgc ctctcccttc ttctttctga agccgtctac gttaggtcag 89761 ctaatctcta gtcaacaaca ttctttgaca tcatgtttga tttatatgag ccttagccta 89821 ggttcttctg acaacttgag tcattgcatc aagtctcttg tagggactag aggtcagcaa 89881 attacggtct atgggccaaa tctagcctgc taccagtttt tgtcaatcaa gttttatggg 89941 aacacagcca tgcccattca tttatgtatt gtctatggct gtttttgcac tacaacagta 90001 gaggtgagta agtacaaaag aaaacatatg gcccacaaaa cctaaaatct ttaccacctg 90061 gcccaaacag gaaatgtttg ctgtcccctg atatagacaa tttgaatcta actagcttct 90121 tgactcccat atttcaaatt tttctctcta ttctaaaatc ctaaagaaag agtcatcttt 90181 gcaggtaaat aaacagaggt aaggtttaat aaatgtcagc aggcttcctg gcactgtcca 90241 gatttaggct gtagtgtgat gacacacctt atttctagct gcattggagt atcagtctcc 90301 ctactggagg tcttgactac tgcagctctt tgcttctttt taggactaga aataggaaga 90361 ctctggtcac aaaatttcaa actgaagcaa cagtatgaca tttggactga ttttagattc 90421 tatcccaggg acagatgctt ttggagcaga ccccgtaagg ctgaggttat aaaaattggc 90481 cagtggccca cctactcact ttatttattt gtttgtttat ttatttttga gatggagtct 90541 cactctgtcg cccaggctgg agtgcacgat ctcagctcag tgcaacctcc gtctcctgga 90601 ttatcatgcc ccagcctccc aagtagctgg gattataggc atgcactacc atgcccagct 90661 atttttgtgt gtgtgtgttt ttagaagaga agaggtttca ccatgttgac caggctggtc 90721 ttgaactcct gacctcaaat gatctgcctg cttcggcctc ccaaagtatt gggattacag 90781 gcgtgagcca ccgcactcac tttagctgag ttttgttcat tccaacttct tctttgccac 90841 tttcctccat tccacatcct tttcgtccag actttgtgta tctgccatat cattaaagtg 90901 gagatattta ttttctctat attatgtctt ctattatttt aataatgata atagctaatc 90961 tttattaggt gcctccttca ttccaggcac tgtgccagga tcttaaattc attgctttgt 91021 tgaatgctca cggcatcctt tgtggtacat acagttgttt tccccgtttt aaaaatggag 91081 gaactgaaac ttggagctat taagcaactt gctcaaggcc acaaaactgg aatatggcag 91141 atcaaggaca tgaatccaga aacctgagaa cttgcactat taatctctag tttacttacc 91201 tctagtatat attgttatct cgagtatatt attctaaatt tttctctaat atataactgc 91261 ctccaggaaa ggtttttctt cttagagaag ctgtagataa gataggcatt actcaaacct 91321 aatgataatt taatccaaaa aactagtgcc agtttataga attaaaagac aaatagcccg 91381 tgacctttgg gtttataaac aatatgctta tcacagttat agcaacggca gcaacaacag 91441 caccatttga acagtgttgt ttacaaaatg catccacgca tattatttca ttcacaagtc 91501 acactcggat ggcttctgtg tcctattcat tcataaaagg tgaaaaaaca agctaaatat 91561 atcggctaca ttttctaaaa caagacattc cttatgtgcc cttgggggtt caaacattta 91621 tattcaactt ctagcaatct tagtggtggc tgtaggagga ctgagacctg ctccttcttc 91681 cctcatacac atttctgctt ctacactgga catttttttt ttcttttttt gagacagagt 91741 ctcgctctgt cgcccaggct ggagtgcagt ggcgccatct cggctcactg caagctccgc 91801 ctcctgggtt cgcaccattc tcctgcctca gcctcccgag tagatgggac tacaggcgcc 91861 ctccaccacg cccagctaat ttttttgtat tttcagtaga gatggggttt caccatgtta 91921 gccaggatgg tctccatctc ctgacctcgt gatccacccg cctcggcttc ccaaagcact 91981 ggacatttta acatttcttt tttccactca gtttacaggt gggagctagg gcataaacta 92041 gaagagagat gtcaaagttg ggaggctgta aaaatatgga gcatgggcta gagaaaacaa 92101 tggttaactg gaggagatgt tacagatctt ttagtccatc cttttatttt tatagataac 92161 aatacaggta gtttccatct attaaatatt tcccatttat taagtacttc ccatatttca 92221 agcattttgc taacacctta acgtgaatta tatgatttaa acctctaaca acaatactaa 92281 ataagcaata tttgttacaa tctccaaatt tcacatgaga aactgaggct tgaatttaac 92341 taatgtgtcc cagataactc aggaaatagg cataaaggag agttctgaac caaatctaat 92401 tccagagcct ttgtatccaa acattatact gtactacttc ctgatctagg caggaaggtg 92461 atttaggccc ataataagtg tgaagaaggg acttgctcca ggtcacaaaa agtgatgtaa 92521 gagtgagctt gaaaaatcct aactcagggc taaatacaat ctgtcccctc cccacctgaa 92581 tatggctaat aaaaataatt gctccttgtt tctctctggt atcctatgtt caacatgcac 92641 cccatctact atttataaaa taagtttcta gtctttattt tcttttctaa ggaataattt 92701 tctgaattat atttgctcag ccacatctgt gaaatagcac tgcagtactc atttcctgag 92761 cctctggatg tacctcggta tttttctgtc tcatttattg taatgaaagt gtagagccta 92821 tcatcatggt ctccaactga agtatctgtc tacttttaga tactatggag accaagccaa 92881 caaattatag aatttcaaca aaggaatcat tgctattctg ctgcaaaggt tctatctctt 92941 tgtttctttt ctttcccttt cttttcatgc aagtcatttt gttttgcctc ttctatgacc 93001 ctggcctcca tgtcttctca ttttattcat ctggagcaat ctatcctttt tagttcactg 93061 aggctcttcc aattgtctta ttgaaaatcc tcttcaaatc ctattttatg ttaagtaatc 93121 ttgtggagtt aagtctgttt ctcccttatg tgtaagacaa attatttcac cactggtgct 93181 gccaacacta ttggtgtttc cacacaaagc atgggatatt aataaccata atggtgatga 93241 tgatcatgat gtagctcacc atgtgccagg cactgttgaa tggtttatat gtatgaactt 93301 ttaaaatcct tagaatagct aaccaacttc tataagttta tggaaacagt aaatgacaaa 93361 actgggcaga gctggttcta tcgtatacga cctggattac tatagtacac agtaaacaag 93421 tttttggcat tactagctat ccccttaatt gcttggcgtt agactcagtt cccttatctg 93481 caaaatggct aattgaaaga gttcagccat tgtacatgta gccaacaacc cactgtagga 93541 gtttaactag cccataacaa tctgttaata ctagtagcta tcattgattg tgctggttta 93601 tgcgcttggc cctccacatt cgtcatctca tttcagcctt cctatgccct acgaggtagg 93661 ctctgttaat aactgcagtt catgcatgag tgaaatgaag cttagagaca tgagataact 93721 ttctccaggc tcttcagcct atgttgttgg agtcagttgt tatgcatact tacaagctga 93781 ttctagaacc caactaccag gtacgatact gtcttacatg agacttttaa aggtaagtat 93841 gatcataata taattacctt agatccatta ttYaccttaa gatgtgattt cactgtaatt 93901 gtcaggactg gggctgaact aggtcagctg aggccagaac tgatgctata gggcttctta 93961 cagaaaaaaa aaaaggagga tgcctttaag cctatggcat cagaataacc ccggcttttt 94021 gtttatataa ttgacttgct atacagccaa acttcaaggt gaaaaatgac ctgtggactg 94081 tggaactcaa acttctctct tgaatcattg cccatcacca gctgtgtact ataccctgca 94141 gactgagcag gcagtaaggt ccttgccaaa cctagagtca gcaattttgg gctgatgaaa 94201 tgcaaatgaa taaaaacagc tataaattta cctccagtct agtgatgtaa gccttttggc 94261 acagctactc aaatcctcat ggcataggaa cttttaaaat gccagttttt acttaattag 94321 ataactcaga aggattaaat attaaagcat gtccaatctg gccttcattc aagatgggct 94381 gggtacaaaa atatcagtag aaggtttaac ctaaaggtaa gaagttatac agcatagacc 94441 ccaggaaacc agcctcacag gctcctaaaa gcaaatcatc agacaaacag aaagataaac 94501 tactgaataa caataaaaag aaaaatcctt tcctcttgct ttatttttct cttaggctag 94561 ctcttggggt tatctcataa ttttgtttgt catggctaaa tagtcaattt gtctttgttc 94621 tggaatgctc agagaatcag tgagtgagcc attattatgg aggaaccctc aaagattcag 94681 gcatatattc tgaataacta cMtttaggaa tagtggatgc ctcccttctc ccccgcctcc 94741 ttcagtatac atataccata tatactatat agtgtatagt ataaagcctg tagctttcta 94801 cccagcattt acacttgaga caatctccca gtttatgact aatctagtgt ttgcttatct 94861 ttcttttctg ttcagcacat ttgcttctgc tgcatgaatc acaagagcag cacaactaaa 94921 gtagcatttt gctttgtgag ccaagcatct [0306] Following is a GRIN3A genomic nucleotide sequence that includes the GRIN3A SNP 'GRTN3A-AA" (SEQ ID NO: ).

AAGTGGTTCTTTGTTCCCTGACCTA[T/C]GTGTTTCTCATAATTTCTACCTGTGAATCTGTTTTCTCCATCAGAGATTAC ACAGAGCAATAAATACATCATTTATAGAGGAAAAGCAGCAGCATTTCAAGACCAAACGTGTGGAAAAGAGGTAAGAAGGGG CCAATGGCAACTGTCTTTATATTTGTAAAATAATCTTTAGAGATCTAACTGTATAATTATTCAGATCAAATCAGGGCAA [0307] Following is an PFTKl genomic nucleotide sequence (SEQ ID NO: 3).

PFTKl REGION GENOMIC >7:89845401-90104900

1 gttttcatat ttgtatcata acattgttat tcaggttggg gtacaattta ctttctgaaa

61 tgaaaacacc atactgcctt gttttttttt ctgttttcta taacttagtc tctttggaat

121 ttttcacaat aactgtttcc ttttccttct tattttatag ctttgaagaa agatgacacc

181 acctttgatg aggtaggtta aatttcttta tctaatgtta gatgtattta atgactacca

241 ggtaaaRtca gtagctgcca actttgtacc tggaaacaaa aaaaatgcct ttaaaacgcg

301 agataacatc tgtttatttc attgcattat tatattttca aattttaaat aatcgttcaa

361 atgagttttg gtagcaagta acagaaatat gtctttttca attaataaat gagctaatta

421 gaagacacat gcaggccttt gtgttgttgc cttcttgcta gtggtagtgc ttgagacacg

481 cagagtgatg tacgtgctta aggcaagtct ggagctgttg gtaagttggg caccatggct

541 caccatggct ccttgcagac ctcagctgaa tcagggtgtg atgtgttgtc gatgccacat

601 attgtctgtc agtctcccaa gggaggagct gacttttcct gttctagttt tcctattctt

661 tgtatatcag atccgtcttg atctacttgc cacaaagtag tgtaaaatac tgttcaagta

721 aggcagagag ttcatatgta attaaatagc atcctgaatg tgattttaaa attgcagtca

781 ttcctgaatt tttgtagtat aagtaggaat caccagagaa atagtgaatg tttacaaaat

841 attttcacag tgccaaagag tgaaatgttt cattgtaacc atcctgagcc acactcattg

901 atctgtgttg taaactgggc cacatgtgta tatagattgt gtttttatat aggaacatgg

961 gtgttatcta tacagtgtgc ttaccctaaa gcctgatgaa agcataaatc agtttggttt

1021 ggtggtttgg tttgttttaa tagttacata ttccatgaaa tatgctacct gtcttccctc

1081 tgctgcagtg cttcagtgag gaaagggcat ttgtgctcat ggaaagtccc cttggccatg

1141 tggctggctg tggtgcatgg caggtctgct cagagagaac ctgctccagg ctgggatttc

1201 tggatggggc caccgtcatt tggctgtcac ggtctgctgc ttcatctgct gcacctgttc

1261 tctttttcct gggctgagct ttacaaagct gtgtgtccct ggactccaaa gcaactttcc

1321 ctgccagcat tcctgtgaca tcctctaaaa aacttaattc ttctaggctt gaagcaatag

1381 aggagtcttt tcttcttcct tcatagtggg caataatgga gttttcctct aaacatgtat

1441 ttctggaatt tcggtagtgt tgttattgag atatttttca ggagagtgtt ttctttcttt

1501 tcaggagcaa tcaatatgag aatatttggt accatttttc tctttgtaaa gaaagtttcc

1561 cctctaatta tgtagataat ttaagcttac ataaaaagag agaaataagg aaaaggagaa

1621 agaaaaaatc tcataaatcc tgttaccccg atacaacaac tgttgaatgt tcttgcttct

1681 ttctccgtgt tttaaaaaaa gcagcccatt attatatccc gcttttttct ttgatatgat

1741 aacattatat tttcccatgt ttttacaaac tcttcctaat catcattagg catttcgaaa

1801 accttttttc ttgcttaaac actgttgtta gtgattagct ttaaaaagca cctgaggctg

1861 gagcccagct gaaggttaaa gatgtgtcaa acctgtaact actccctctc tctgttattc

1921 tgaaacctct gtatagtcaa aggtctggag tttgtaattt gggtcaaaat catccttagc

1981 ttttgcaaag tggcttcctt cctctgccac aagagattgt aaactatcac aaatcagtaa

2041 atcacagaat gctctacttg gaagatccat tggaaataat aattttccca ctccatcatt

2101 acacagatga agaaattgag atccagaagg ggcaagtcat ttccagctaa tgaaggaaag

2161 actcaaggcc agaaaatctt gggagatagt ggtaatgaag gcatgccggg gtataatccc

2221 caattcaact accctctgtt tgggcatttg acttattaat ttcatatcct ttgtaaaata

2281 gagataataa tagtatcttt cctttaaggg ttaagataat taaataaggt aatgcatatg

2341 aaggtttcag aataatggct cacaaaaagt gaatagctca taattggtgt tatcatcttc

2401 attgccttca tcatcaccat catcatcgtc attgatgctt tcactttgac atccaccttc

2461 tgtagttgga agggctacag agtagataga aggattaaaa atgaagaatt acagctatga

2521 ggagagttaa tttcagatat tcctctaaca tttcacctaa agcttcatgt gatgacttgc

2581 atattaaaac tgagaaaata ttatctaaaa cccaccattg tttagattcc gtatgggggt

2641 gattggattc actttttaat ccctgagtgt gttgctcgta gttaactttc agtacgtatc

2701 tattgaatgt gagtaaatat ctattgtaga ggagtagaga gagtgatgaa ttaggtgtta

2761 ggcaatgtgg attctcatct gccactttct agttatttgg gcaggtcgtt taacttaccc

2821. cggccatgac attctcattt gtaaaatcag ttgaactatg atcttcaagt tgcctcttag

2881 ctctaaatgt aggattctaa ataatgtaac aaccaacata agattacaat tttttttcat

2941 gttttatgtc agacaggtaa tgtactgacc ttgtagtaag gtttgaggga ggcacatctt

3001 acacatgagg tgaaacccca atcatcacgc ttatgaacta tacaaaagga tcaaaatgac

3061 aattttatca catcagaaaa gagcactaaa actctgctta tgtacatagg aactgagttc

3121 ttctgtgatc attttcagat tataatagta gaaatttttt tgaacgcttg ttttttacct

3181 tctctctcct ggagctgggg aactctacag tccattggaa tcaattcaga ttttagtctt

3241 aaaactttga gggttgggtc agcttcttag gtatgcaata aggtgtggca actctcctta 3301 gtatttatga gctggaaggc tccttatttc aaggagtggc ctcttccaga gagtgcctga

3361 gctggagttt ggtaacaact ccctgattca tgtagaggat gcctctagag tatgtgtcaa

3421 atgtttgacc ttgaacacag cagaaaaaga aatacagact tatttaatca tagactgaaa

3481 tgccatgatt tcagtctaat ctgctaattt tcaaaaccag actggaatta tattcaggaa

3541 ctatgcttgt tgtaaactgg gctgtgtttg tgagcacacg tgtgtgtttg tgtgtgtgtt

3601 taattgaaca gtttagaagt taagtattga gggcttcagg tatttacaat aagcaaacaa

3661 taggaatttt gctgaaggcg gtcatagttg gagaggggac attctatgaa tgatcatttt

3721 gcttttcatt cattgtgtat ttggtccctg actacaatat tagccattta atgttctgtg

3781 gtctaaatct acacatttta cttggatgga ctaatcattt ctaaaatatc ccaagtaaaa

3841 ttttattagt ttcagtcctt ttcccctccc agcttcttga tgtttggaag ggtttgacat

3901 agtacttggc cacagtgaag gggctacata attattggag aaacacatgg ttaagctaga

3961 ttgaaggtga aagaagattg gtattttgtg tcatagtttt tagtggacat aatgtttcta

4021 gtgacattgt gatgagagtt ttgggtaaag catcaacttc atacctgtga aatgactgca

4081 gaaatttcca aatgtctttt tacccttttg ttcctaataa atgaccagac catgtcctta

4141 agtggcccca tttttcctgg aataatgaac aataactaca ctatgatttc tggtgaattt

4201 ttgaatttta tttttgattt aatgatttat tttagaatat taatgatacc taatatatga

4261 aaggtcagaa aatacagata atgtccacca atgtaaaatt accacgcgta aaaccttttg

4321 aactttggag acaaaagctc taattaagtg tatgtgtatg tgtatgtgga aatagttgga

4381 aatggtgata gctacagcaa ttcatgaatt gttctcatgg gtaaattaaa aggttaactc

4441 atgcagttct gctttatccc tctgtttttt agctttgatg attgccagaa caaagtgttg

4501 gctctgcctg gctctttggt gagaaataca aaatttttag caattagaat aaacctttga

4561 aatgcaaaga atttcatatg tttatggcat ataatccaga taattaagca cttagtttgt

4621 ttcctaaaaa tgggtgaccg tgtatgagtt ttctaattct tctctgcttt ggtgagttat

4681 tttatgtttg tgaagtagaa ggctgctagc acttattttg tcattttcca gctattttat

4741 tttttcaaat cctaggaaaa tgtatacaaa gcgtataaaa ttaaaaaaaa ttctacatct

4801 ggtctgtgag tgctccaagc acatttttat aggttaactt gcttacttta catttagtat

4861 aacaattctg ttaggtggag actgtgcaca atgatattgg cttctagtcc atgtccctct

4921 ttgttatttt atataaagat ataataccag agataataaa ggtggcagtt attattatta

4981 tttttttgag acttggtgtc ccttggtcat ccagtttgga gtacagtggt gccatcgcgg

5041 ctcactgcag cctccacctc caaggcccaa cctatcctcc cacctcagcc ttctaagtag

5101 ctgggaccac aggcatccac caccacctgg ctaatttttg tattttttgt agagatggag

5161 tctcaccata ttgttcatgc tggtctcgaa ctcctggtct caggtgatcc tcccatctca

5221 gcctcctaaa gtgttgggat tacaggtgtg agccatcaca tacagccatg cagtgatttt

5281 tatgagaacc agaatctagg gatgatatgg tttggatcgt gtccctgcca aatctcgtgt

5341 tggaaggggg gcctggtggg aggtgattgg attgtggggg tggatccttc ttgaatgatt

5401 tagaaccatc cccttggtgc tgttctggtg atagtgaggg aattcttgtg agagctggtt

5461 gtttaaaagt gtgtagcacc tcccccttcg ctgtcttgct cttagcttct gccatgtaag

5521 aagctggctc tccctttgcc tactgccagg attggaagct tcctgaggcc tccttggaag

5581 cagaagtcac taggattcct gtacatcctg catatccgtg agccaattca gcctcctttc

5641 tttataaatt acctggtctc aggaatttct ttatagcaat gtgaaaatgg actaatacaa

5701 gtggttagat acaaatatga tttgtggata tttctggtca ttcttttcca tttattgagc

5761 atggtggaag ctggttcagt cttttctcta ccctgactat caccattaag ggctgtctca

5821 gtgtccatat ggatgatgta tacgctgtca tacaacattc tagcatccct gactttctcg

5881 tctcatacct gctttaccct tatttggttt ctgcaggaac tgcatcttac tgggactgtc

5941 ctagatttaa aatattaaat cccactaaca atctttcctg tttagctttc tcactgctgc

6001 tgtattccct gtatcttttc tttgccggct tccagtttct agatgatccc ttctctgcct

6061 gtcccatccc attctcatag tccataaccc attctccccc atagttcctt ccctgatcac

6121 tcagggaaca tcactctctt gctggtatcc tcaatggcct tacccctttg tacttcattt

6181 gtaatgtacg ctgccagccc ttgattttga cctggcatct tttcctatct tacctagtgg

6241 ctgccaagag ctgcttgagg aaatcactct ataaataaat ttatcatttc catccttagc

6301 tggaacgtca ggcaactgtg gaccatcttg catttgtgtc cttgtgccgc tggcctgttt

6361 cctgctgaac tcttttcact ccccctaagc cttcttgcga ccctcctcca ccctttcttc

6421 ttttagtaga aggctttctc tctgttagtt tcctagggct gccctagcaa agtaccacaa

6481 actgtgtgac ttaaataaca gaatttttat tgtctcacag ttctggagac cagaa'gtctg

6541 acaaacagta gcagagttgg ttctttcaga ggactgttag agaaggctcc attccaggcc

6601 tctcccctta gctctagatg actaccttct ccctgtgtct ttttacattg ttttccctta

6661 atgcatggct gtctatctaa atttcccctt tttacaagga tacaagtcat attagattag

6721) gggctcaccc tacttcagta tgacctctta atttaattac atctgtacga cccccttttc

6781 aaaataagat cacttttgga ggtactgggg attaagactt cgatatatga atttttggtg

6841 gacacaattc aacctgtaat accctccaac ttcttagagc ccttaatacc gttaggtgtc

6901 cactccctgt caacatcctg cccattcatg taccctcatt tgctccagtc ttacctcctt

6961 ttttcccatt gatctcagag ggggttttgt cctttgtttt gttccaggcc agttcctcct

7021 cctgtcttct caattccttt ccctcttttc tactccagaa gcttacataa ttgattcttt

7081 cctttctttt ctatgttttc tgccctctcc tttttctaga tactttcacc ataggctctg

7141 aacatgctta agtcttcccc atctcgtcca taacttcagc cttctgtcct ctatgatcag

7201 ttttcatgct ctgattgagt ggttgatgta cacttgacgt cagtgtggct gactcagctt 7261 tctattctaa cctccacatc cagatgtcca actgcccact agaagtttct gccgctatgt

7321 ctcacagtca ccttgatttc agcacatatc attaattctt gtatttcccc aagcatgcat

7381 cttctcttgt tcctctctct gctattggct gtaccagcca catgattttc caagctaaaa

7441 acctgatgct atcctaacct tttctccaac cccgcatcca ggtgttggct tggtttttgt

7501 tccttgctgt catatccatt ctcacagctg atgtgcacac tcagctttgt catctcttcc

7561 tggacttgga gtagttgtat aactgacttc cctgcctacg acttgcctcc tgctccaaca

7621 gaatgatggg tctgaaatac aaatttgccg atcccctgct tactgcttta aaaggtgcag

7681 gtttaactcc atactcctag cttatctttc aaggcctttc acgatctatc tctttcgtac

7741 cttttgactc ttatcaaaca gttatctttg tgtgtttttt tttttttttt tttgagatgg

7801 agtctcactc tgtcacccag gctggagtgc agtggcgcaa tctcggctca ctgcaacctc

7861 cacctccagg gttcaagtga ttctcctgcc tcagcctccc aggtagctgg gattacagac

7921 gcccaccacc acacccagct aatttttgta tttttagtag agacggggtt tcaccaggtt

7981 ggctaggttg gtcataaact ccagacctca ggtgatccac ccgtcttggc ctcccaaagt

8041 gctgggatta caggggtgag ccagcacacc tggcttcaaa cagttatctt ttattttcgt

8101 gacttcatta tcattgcagc tgctgccatc vtcagttcaga accttttcac ttttacctat

8161 tttagttcaa taaactcttc attggtatca ctgctccatc ttattcctcc actcagcctt

8221 cccaaaacat ctttcttgtc atagtactcc cctgttcaaa gattcatgca tcaaatgacg

8281 tttgttttat gtcaggctgg atatggtctc agcctgactc ttgatctagt tcagcctcac

8341 aggcatttat gggttgacca tctctcagca tcttacaggg ctgggcctgg gtggagattc

8401 aatctcactc tctcttatag taagatttta taggccaggc acggtggctc acgcctgtaa

8461 tcccaacact atgggaggtc gaggcaggtg gatcacttga ggtcaggagt tcgagaccag

8521 cctggccaac gtggtgaaac cctgtctcta ccaaaaatat aaaaattagc tgggtgtggt

8581 ggtgggtacc tgtaatccca gctactcggg aggctgaggc aggaaaatcg cctgaacccg

8641 ggaggcggag gttgcagtga gccgagattg tgccactgca ctccagcccg ggtgacagag

8701 agagactctg tctcaaaaaa aaaaaaaaaa aaaaaagatt ttatattact ttctgtactg

8761 ttttattttc actgtggtca tatctgccag tcctagatgc tatgaacctt ccatgcaaga

8821 ggtctaaaag ttagactgtt ctttaattat gccagtaatc cagaaagtca ttatatttca

8881 aattcagcat ttaagatagc tgaaaaagaa catcactacc tccttaattc tctcattgga

8941 aatttagttt taattttctg atgcttaaaa ctttctgtgc ttcagttttt cctttttata

9001 aatgtttgat catatttacc atctccctaa ttatggtaga cataattatc ataattaggt

9061 ctagtcccag acagtggctc aaatgtctgc gtagtgctgt aaagattcag agaggaagta

9121 catgtcacaa agtgcaagat gtatgacatt tgggagaatt agtcactttc aatttgtaat

9181 tctcaaaagg cagaatatta cagaaatgga aaacatgagt agtgtcctct ttccgttgtg

9241 agcaccctgc atcctggtgg caggctgtat agcctgtagg aagtctctgc tgtaagggtg

9301 gttagtgttc cctcctgggc agtgctctga tttgcatgtt tgaattcatt tgttgaaagc

9361 tgacctttgg gccgggcctg gtggcaatcc cagcaccttg ggagggatca cttgaggtca

9421 ggagtttgag accagcctgg ccaacgtagt gaaaccctgt gtctactaaa aatacaaaaa

9481 ttagccaggc gtggtggcag gtgcccgtaa tcccagctac ttgggaggcc gaggcaagag

9541 aattgcttga acctgggagt cagagtttgc agtgagctga gatcgtgcca ctgcacacca

9601 gcctgggtga cagagcgaga ctctgtctca¹ aaaataaaaa aaaaataaaa aaagacgctg

9661 acctttgacg taggaagtct ttctgtacag cctaactact ctattttctt caacaagtgc

9721 aaaatgggct cagctgcagt acattatgcc tattttcctt ctgactggaa tttgagtcat

9781 caatttagaa atttttatat tgctgggttg tgattgggat ggcttctcct attaggaacc

9841 atagcaatca ttgaaatcag tgaagccaag gtgggtcaga gttttctcag gactggacca

9901 tagattccag tcctgagtgt ttgagactat tttttatagt cccaaacact tttttttttt

9961 ttttttgaga tggagtttcg ctcttgttgc ctaggctgga gtgcaatggt gcgatcttgg

10021 gtcactgcaa cctctgcttc ctgggttcaa gtgattctcc tgcctcagcc tcccaagtag

10081 gtgggattac aggcatgcgc cacctgcctg gctaattttg tatttttagt agagacaggg

10141 tttcactgtg ttggtcaggc tggtctcaaa ctcctgatct caagtgatcc acccgccttg

10201 gcctcccaaa gtgctgggat tacaggcata agccaccgtc cccggcctag ttccaaacac

10261 tcttaactct tattattctt gtcataaaac ttataaaagg cataattaca agatattgga

10321 accagcagtt tgctttcagt tttgcaagct taatttcttt aggtctcatc agcgtcttaa

10381 aggagctttc atcattttaa gggaataatt gaagtaatgt tcactttccc ttctgaatct

10441 attttatttt caatgtgtaa agttctggtt atttttccaa cttactattt attttttaag

10501 ttttccttct ttcttagcaa cttagttttc ttaaatttct ttttaaaatt aattttttta

10561 aaaaaataat aaaaaagatg gcatctcatt gtattgccca gactggtctt gaactcctgg

10621 gctcaagcag tccaccagtt tcagcctctc aaaatgctgg aattacagac atgagccact

10681 gtacctggct gtcttttagt tttattttat taactctttt gaaatgaact gttgtttctt

10741 ttaggcatat gagcctggga attttcttaa aattaattaa tttatttatt tattttgcct

10801 tggtaagttt attgtgacct gggtgttcca cgagcatcct aaacttaggc tggggatatg

10861 gaaaattatt ttacagtggt tttaggaaaa agccaggtat tagcaaaaaa ttataagatt

10921 ctgaaatcat ctgcaagtat ggcatgtctt atagtgcaac attatatgat taatttttta

10981 ataatgaaat taatagtttt cctgtttttc aatagctact ctaaattcta tgataatgat

11041 gaatcttatg tgtatgagta aggaatgtgt tgaaaaaaaa ttttaaggtt tttatgaccc

11101 atgtagttat aatacgatag aaaaaaagtt ttcaatatgc acttttatac ctagatgaaa

11161 atgcatcagg caagtactta ttcgaccttt cactgattaa gaatatcttt ctccaatctt 11221 gcaagttaca atttaaaaga catttggaat tgcttagaga acccagggag tcctggattc

11281 tacaattctg tgtgctcttt tgtgttttct cagtctctga ctaccctcat gtaagatgtc

11341 tataaagtgt ggtatttaga ataaaactat gatgtttttc agagtttggg aactattcta

11401 gtctagcaga tctcgaacac gttataactc tgtgttctga tcagctgaaa tattgaagtg

11461 tgtgaatact tttctttaaa aaatgagtat attgaagtca gtctttcaat tatgttttgg

11521 tatttttttt gagtgggaaa gaagggggct gagttgcagt tagagtacca ggaatttggc

11581 ttattccaga tttgcccatg ggaatgtgcc aaatatgaaa ttataacctg tgacatatct

11641 cttggataac ttagttgtct tggagtatta gtttttctat tttaacggat tttcaaaaaa

11701 ggagattgca ccagttctat aaagcagtga tgggctgtgg tagaggtgga gggtgagagt

11761 tttcaaagtg ctctgtaaag attttggtgc aggtctcttc acttccccta tcaaaatatt

11821 cacgcacctt gaaaattttg ctgctgtagt taggaagggt tgttattggg ggtgtgtcat

11881 atccctcaag tgagttcaga gtttgagagc ctttctttta aaatatctgt tgctgaatta

11941 ttaggagttg aagatggata ttggtacaat catatgcaac cttaattttt tttggaacag

12001 ctcttggttt tagataatgc tttctgattt ttgattcaga aaatatagtc ttcttagtcc

12061 taaaattgtg tatttattaa tatcaaattc ataatccaga aattttagcc aaaagaaaaa

12121 ctaaaacagt gatacagaaa tttctaacaa agaaatggat aagtaagcat tattttataa

12181 cagagaaaaa tgagtgagaa taacttatgg ttacttttga ttttaatgaa aacatttttt

12241 attaaaaaat ataggtaaag aagagagatg ttagttacag ttattcaggg catgaattac

12301 aaattctttt gtgttatagg tgctcgttta ttttaaatct tcagctatat agctctcttt

12361 gtattgtctt caagtcaata tgatggagaa tgtcctgcag tgcctgattc tcttctctta

12421 aaaggcagac tatttaatct tacaaatgag catccttggg tcattacata ttggggttca

12481 ggtgtgcaaa aggcttggta acatatggct tgtccccaga tgccctaatt gagttcaaaa

12541 ctttccccaa gaggtttgca ttactttatc taaatgatgt gttacatgtg caacaaaaaa

12601 ggtgttttag tcatgaaagg aaaaaaataa atgtgtactt gcaagataca atgcaaattg

12661 tacagtgtac attgcactaa tttctatata gttattagaa gataaaaaag attaaaaccc

12721 ataaaagtga cattaattgg atgaccacag ttttggatga tgcactttga tgatcttcag

12781 cattcccttt agttacctta ttatatcatc atcatcatat atatatatgt gtgcctgtgt

12841 atatatacac atattttcct ccattttgat tatttttttt tcaggcaaga tagttaggca

12901 tattaaactc aatggtggac ttttttttca gcttcaaaac cttacctctt atcacaatta

12961 catgtgtttc attgaataat tttaatattt gctattaaga aaagtaatta tgttcatggc

13021 agaacatgta taaaatagaa attattattt acagtgaaac agccattgta tgtagagtat

13081 gatctcggtt ttgtaagatt ataagtatcc tctccatggg ggaaaacatc tgaaaaaaag

13141 gaaatacaac aaatggataa tggggagatt ggggtttatt gaaattgtga cttgctcaga

13201 gtcccttagc tagaaggtgg tggtttaatc tagtattcta acctagtctc tctgcatcca

13261 aactacgctg cctcccagga gaagggagaa agggagaaat aacatctagg tactactact

13321 acaggtgcag catatagttg ggaaaacaaa gttcttacaa agaaacaact gattttggta

13381 gtaattctag cagatgaatt actgctagaa ttaggcctaa aaaaggccta aaagtgaacc

13441 ttaaagattc ctgccataga tctatgtcat ttttgaactg agttacacac attttacaga

13501 gaggaaactg agacccaggg agattaaatc attatgttac taaataatgt tgctgaagag

13561 aacatggttg attagtcgtt gtgaaatcaa gggagtttct ttgctgaatt actctttagg

13621 ttttagattt cagtttcaag gttacgttaa aactaagctt gtattgccat ttttatctgg

13681 atttaggtgg ggagtgggtg gattgtttgg tgagatgtaa acttgatcct tcgggtagta

13741 atttgtttag taaaaatttc ctgctagaca tgagggctct gtagtcaatg aagattatgg

13801 aaggttaact attggttgag gtaccatgga ccaccttgtg atatacagac tggtttgagc

13861 tggaaggcat gatgagaaaa ctgctgtgtt ttaactagca tgttctgaaa aaagtgtcag

13921 aacatctttc aatgggtgta aattgccttc actgagcaag gcaaatggtt agtattgaac

13981 agaaaatgtc agataataaa ttcattcatt ttcttcgaat cctgaatata tacacttgga

14041 ttattagctt gtgcgtgtga agccactctg gcttcatttt tatttcatat tatgacagct

14101 aaaatctttg tgaagattaa aaatatggag gaaacagaca ggtttttaat atttacatct

14161 tagaaagatg aagactttag gtgggtatag ggagaaacat tcaatacttt ggattctttt

14221 ttattggtag agtgagtgct aagaaaaggg atagaccaat tttttttctc tctttctctc

14281 cttttccttt acgtaaacat aaaatgcttc caattcactg gattttcttc tatgcttcca

14341 atatcattgc attttcttct ttcctttttc tttgttcttt ctgaaaacac cttgcttttg

14401 gtggtttagt tgccagccac tgggctccac cttgccctca agcctttcat gacccaggtg

14461 ctgggtccag tgaatgaact tttggttgct tttgccatct ttgtaccaga cataatactt

14521 ttttgatgtg caactggtgc aggcaaggga agatgaaggg ggaagtctca ggcaggagtt

14581 agagatgttt tataatgatt ggccgtcttc tgctattaga gcacagaatt atggctccta

14641 aaaaaagact tggcttttct gatgatcccc actgcattta atggactagt tctgcaagta

14701 tttacattgt ttgatgtact ttatctttcc tttttaccat cagttgagtt ggaaagattt

14761 gaggacacat acagaaagag tgattttaga ttcttttctg ataccatttg gactcagaag

14821 taggagaatt tgtgccttat tgtgtctttt tcttttgctt tttgatgaga aggagcaggg

14881 aagtaaaaat ctcaagagag cagaatcagt tttccggtca ccaagctcat taagttaata

14941 tttactttta aaatgaatgt atttgccagc ccttcccact gtttgtttgg gaagcattta

15001 acatacattt gagagcctct aacttgtttc cacctccatt gggtatttca cttctcagac

15061 tggtggcggt gagtgtgatg cgtggatccc agttgtaaca tctgtttctg tcacttcaat

15121 attacgttta tcttgagggt aaaggaaggg aaagaaatga agctaaggca atttttccct 15181 gtttttctgt gtctactgca caatattgat tgaatgatat ttaacatctc tagtgctttt 15241 aagcccattt caaataacac aattgacaca tatgtagggg tttaaggaaa ctggacattt 15301 aaataaaaga tacagcctga aaactcaaag attacatttg aaaatctctt tccagtgttc 15361 cataaaatga tatttacagt ttttttgtct cttgatacct gcaactttct agatgaaagc 15421 tgttattttt ctttaggcct cagatgagta ttttttcact attaaaaatt ttaatgaaca 15481 taaaatactg attattttaa cttctataaa tatttaataa ccaaggtctt caggtacatt 15541 gtatcgtaat ttctgttggt tttttaaagc ttgctgtgtg agagaactga ccgttatgtt 15601 taattatttg aaggctgttt tggggaatgt aaaaattgat actgaaggaa aaaaagaact 15661 gggtgcggtg gctcacacct gtaatcccag cattttggga ggacgaggtg ggcgcattgc 15721 ttgaggccag gagtttgaaa tcagcctggc caacatggca aaaccctgtc tctactaaaa 15781 aatacaaaag ttagctggtg tggtggccca agcccgtagt cccagctact tgggaggctg 15841 aggcaggaga atcgcttgaa cccaggaggc agaggttgta gtgagccgag attgtgaccc 15901 tgtactccag cctgggtgac agagcaagac tctcgaaaca acaacaacaa aaacaaatac 15961 agagagatat gactctttat tcatgatcta gttgacatcc ccttgctgtt acaagtatgt 16021 atattaaatg tttctgtaat acatgtccta caagatgatg tatcaatgta tagtattttt 16081 gtctagttgg caacctgaga aatatttatg agctttcagt gggacatcta ccacttcaag 16141 gatcagcaag gcacagacaa gccacaggaa ttattaactc aacaaattat taacttatca 16201 aattaattat ctaattatta actcagttga ctgggctggg tatttttctt tgagatttct 16261 tttatttttg gtggatcgat tgattggcac tggcatgtca ggggcaatga caatgctgtc 16321 tctagctgaa actctgtgct ctccagacgg cggtgagtga cgcttctcca cctgaacaac 16381 ctcagaatct gggtgtgagt ggaaagtgca agagcgctgg aatctccttc acccatcttc 16441 cagcttgtcc ccgtatccct atttataatc tgtgtgaggc catctagtag tctccttttc 16501 cttatctgta caacagaggt aaccctctcc acctggcaaa gttgtaagaa ttaatgaaat 16561 aatgcttgta attcctgtaa agggtcttgg cacggagcag gcaccaccgt ttcatagagc 16621 tgggctgtgc ctctcaaagc attggcacat gcagtgtggt gctgcacgtg acatttgggc 16681 catcctccac atgagtcctc acatctgtgg gcacaagctg aggggcacat ggagactcct 16741 ggctttatga tgggaacacc agcagtctaa ttttaggaac ctccacattt taaagagggg 16801 gaaactgagt ctgtaaagtc caaatttagg cttcctcctt ttgttgcccc acttctgccc 16861 atcacagtgg ccttgctatg accacgtgtt actggatctg gcagaaaagg aatgtccact 16921 ggtggggttt gtatgccagg tggtttttgg tggatgggag tttgcatccc acaagacagt 16981 caggagctct gcatatgtga gcactactaa ctcatgtttt agaaggaaac agcgttcaca 17041 tatgtcacat ctacagtgtg catctggtca caggatttcc agaggtctat gatgattacc 17101 ccagatacag agggagggaa aatctccctg tacctcctcg tttttgggtt ggtgcctcgc 17161 cagaggtttt ctgattcttc ttggttccct ttcttgtttg cctgcatttg tactggctca 17221 tgtttattgt ctggcagggg aagccccttt gtctctactc catgtgtctt gtgttcatgt 17281 gttgagtaac tggggcattt tctccattgt agacatcaca gtcttgggac ctgttgtttg 17341 agcagatgtt cacatcctta aaatactctc ttccccctgc aagactgtgt aaggttcctg 17401 agggcagaga cagcatttct acctctctct gaatctcatt ctttcagaac agtcctttgc 17461 acctagtagg tgctgaataa aagttgcttg agagaataaa cagataatac ttttggagtc 17521 ttttaggtga atttgttccc ataattcaga ctttttttcc ttccttcctt ccttccttcc 17581 ttccttcctt ccttccttcc ttccttcctt cctgccttcc tgccttcctg ccttccttcc 17641 ttccttcctt tgccacagga attcaccaac tgtttattca tggggatggg atttatctta 17701 aatgtttttt ctgtatggac cttatttaat tttcccagta atgttggcac tattatttct 17761 atttttacag atggggaaac ggaagtttag agaagttaag caactagcac agggtcacag 17821 ggctagtgaa gctccagaag tggaggtgac ccagacacgg ccctcacgcc agtttaagta 17881 gcagctggag agacctgctg gattgttggc ctttgaaagg gaacattgaa agttgcttgc 17941 atttgatgat gattgggtta catttacttg aattgtgtaa cttttaagtt gcaaattaat 18001 gctaaaagtg tattagggta gccttaggct gtgggactaa ttgagaaacg aagtacaatg 18061 gaagtgctgc aagcaaatgg attttcctgc ttagagcagg tatttactat taatcctgtg 18121 gcatttgcct taaggagttg gagtctttct tagctaatta aaaagtaccg gtcagatgtt 18181 gagtgttgtc aataatttag tgcctgcatc tttttatccc tgttgtttgg aaactacaat 18241 ttggaatatt ctgtgcacat ttaaaaaaat aaatgactgt ctgtgtggta atgtttttgc 18301 ttagtaaatg tatgcattat catcttgagc ttatgagttt tctgtacttt tcttgaaact 18361 tttattagta gaaaaactgt caatctaacg cggtgatctt tctctgaagt cctcagcatg 18421 caattgggca taaaagttgt gatccctgag cacatgtttt ggggttaatc ctattcatat 18481 ttttggtttt cttcttcatt cccaagatat ataaaaatta aaagcatttg agattgcaca 18541 ttagtgcatt ggatttttat ctggggtggt cccttctcta agtgggtagt gggagtgtgg 18601 aagggtgaag caatatctac taaccttatt tgtgatttgg gagctagatt atcctttttc 18661 caaaacatcc taagcgaaga ctaccctgac tgtgttttta ctgaaagctc ttcctgtcat 18721 tctgggtagt ttatactgtt tatttacctt gtataaggaa attctttctt tactgtccca 18781 tcttatctca gatcaaagtt tccacccagg gatcctactt aaaaaatatt gtctgagact 18841 gcatgtgttt tctttctttt tttttctttt tttttttttt tagcactctg agtttttgct 18901 ccatctgcac tctctggttt tccgtccttc tatttatgac aattgtgtaa tgaatattca 18961 tagtttccat tattaatgta atagcatgcc atttgtcagc tcactggctt tctcgtatta 19021 tatatatatt tttaaaaatt ctttttattt attttaaaat ttttgttgtc tttgtcttcc 19081 gtaatctttt ttctttatag agtttgtgat catgtgtttt tcctctaacc cagacatata 19141 cgtaggtcta aaactgcaca gtgcaggatg tcaaatggct taaaaggatt tctgctgtga

19201 ctgaaagagt ggatctgtgc ccttctgggg gtgtaggctg accacatgaa taccaataat

19261 tagacatctt ttattttaag aaatgggcag ctgtttcttt agttgaattt tgatatcttt

19321 atagttactt tgctttcttt aaagggcttt tctctgtata tatgcatctc tttggcaggg

19381 ttgatggcag actgggatac tggcatggca atagtgggaa agaaggaagg aaaaaaagca

19441 caactgaaaa ggaaaacctg aagtgttctg aatattagat tttaaggtat tagttgtttt

19501 tttaagtttt ctttttcaat ttattaaaaa gtagaatatg taagtattgt gaatatcagg

19561 ttttttttca gtgattttaa ggtaaaattt tcaccgtctc acacttgatc agaaagtcta

19621 gcaattaact ttccccttga gcatcctgag ccatccctca gaggtttgat taggatggca

19681 gttacagtgg tgataatgcc ttcctggagt tttcaagcct tttatttaaa tcagtgctta

19741 ttatctctca ctgttgtttt aaaacacagc tcctgaacct gaaagtccag tgaagatttc

19801 atctggaagg ttgggttact gggtgtgtgg gattagaggc acagactgct gtcttcctct

19861 ttgtcatcat cagaagccct gaaacccctt ttcatgcttg ctaagattag gcaggagtgt

19921 cattgcatat ttataataca tattttgtag ggcttcatag tttacaaaac aatttcatat

19981 gatatttcag tgaatttttg caacaaaaca gccctgtgaa ggagtggaca tgtagtttca

20041 tctctgtttt gtagaggtgg aaattgtact cagggaaggt aagtgctgtt ccccaggcca

20101 cagtcttctg ttctcacagt ggagctttgt ctgggaccca ggtttcctgc cctctcaccc

20161 tcaccccctt attctgcttc tcctgaaaag gtcaggattt aaagacattg cattcagcat

20221 cagattaggg gaggtatgtg acctagaaac cctagcaatg tggatttcga aaaggtagtt

20281 atttcttcta tttcataaca ttaatgacaa ataatgagtc actttctaat tttctattca

20341 gacaaacgca ttttgttctc tatattctgt gtttctgtgt tctagattta tggacctgaa

20401 tgcttaagtt tacatagcag tgagaaacat aaatcctatt ttgtattctt taggtacctc

20461 aagagccaac agctcaaact gtggaggcag tactggcagt ttggctaaga ggaaagagag

20521 agaagtggct agcaaccatc ccctgagaat aggagaaaat gagatatttc tgacagtatt

20581 acaaactgga gcagaggttt ggtgataaca ggaagctgct tatgagaagg atttagcatt

20641 agatatggat ttgaaactct gctccaccac ttagtagctt tgttaccatg aacagacagt

20701 tgcttaatct ccctgagctt cagcgtcctc atctgcgagt gaaggctgtg aggcagtctc

20761 atatattata gggcgataag tcaggatgct ggaaccagct gcttggtgtc ataaacctgt

20821 agtcagtcat atccaggctc caacactcct tggctatgtg aagcttaaca tctcgatgcc

20881 tcagcttcct catctcgaac aggaggatgc taataatact tagctcatag agttgatagg

20941 atcacaacag tttcaaaacg tgtaaaacac ttaaaacggc gaatggctca tagtaaattc

21001 tctactaaaa gttaattgtg tctgggcaca gtggctcata atctcagtgc ttcgggagat

21061 caaggaagga ggactgcttg agacaagcct gggcaatata acaagacccc agttctaaaa

21121 aataaaaaaa aacctggcca ggcgtggtga cacatgccca ttgtcctagc tactcagaag

21181 gctgaggcag tgggatggct tgagtccagg agtgcaaggc cgaagtgagc tgcaatggct

21241 tcactgccct ccagcctggg caacatagcg agactctgtc tttaaaaaag gttattttta

21301 agtggaataa gttacggtag tacctgccat gtacattaag ctttcagttg gttagtttct

21361 tcctctccta tttagatgtt ttgaagttaa gcctaatgaa agcaattcaa aaaccactaa

21421 aatacattta ttttaatatt tgcatcacat ttaatttgtg taattattga tctcttatac

21481 cttggacatt cattttttaa atgtagtatt ttaaatgtaa tatttttgca ctattaatca

21541 cttaaaatat tgtgttatat catgtctagg aaattcatta taggcctttc taagagagaa

21601 ggctttgtga taaaagccag ctgcccagac atttccaaac cctcctcacc catcccccag

21661 catgctacag aagcagcagg ctggcagagg tccagatttc ctaagtgatg ggattgttcc

21721 cccggccagg aatgagagga atctgcctag attggagatg gctttagcta ctttgctttt

21781 cttcgtactc gtagtcttat tcccaaactg aatctgaccc agcaccattt tccattattg

21841 gagatgtttt aacactgtgt gtggaggtct tgctatttaa acaatgattt ctgaatctac

21901 tttttaattc catgggagct tttccatttt tctttgtact atggaagaag aactatgagt

21961 taattttaat ttatagttat acctctgcaa atcaatacaa tctttctgtg acttccactg

22021 gtagcaccat tcttgatctg aggcgagtat tgggattgtg gttttacttt cccatttact

22081 tagaggcggg aaggtttagt tatttgaatg ccttagacca ggaaattatt ggctattgtc

22141 agtggaattt gtttatcttt tccaccccta cattcctagg ctgtgagaga actggtcatc

22201 actgtgattg cacctcagtt tttatcagtt cctcccccag cgctattttt attaaatact

22261 tgatgtttct ctcttctttg ggtataaatt tagagaccct caggcagaca tttctgaaag

22321 ggctctctta ctcagctgtt gttaaaatga agagatcaat actgccaagc acctcttttt

22381 gtttggctac ctccaaaatt catgttttct gcagttattc tctaggatta tctgtgatta

22441 tctgtaattt ctataattta tctatagatt ataatctaaa ctgaagattg atgcatgtat

22501 aattctaatg agcttctcga ccagcactgt tcaatagata cataatgcaa atttcatgtc

22561 attaacattt ttcttgtagt tacgttaaaa acgtaaaaga agccaggtgt tgtggctcag

22621 gcctataatc ctaggtcttt cagaggctaa ggtgggagga tggcttgagc ccaggagttg

22681 gagaccagcc tgggcaatat agtgaaacct catctctaca aaaaaataaa attagccagg

22741 tgtgatgtgt gtctgtcatg tagtcctagc tgctccacag gttgaggtgg gacgatcact

22801 tgagcccaga gtttgaggct gcagtgagct ctgattgcac catcgcactc cagtctcggt

22861 gatagaatga gaccctgtct caaaaaacaa aacaaaacaa aaacagcaaa aaacaaaaac

22921 aaaaacaaaa caaaaaaaga aaagtaaaag aaacagataa ctttactttt attatacttg

22981 aaaaacccca tatataaaaa tataatttgg acattaaagt tattattgag atttttactc

23041 ttattttgta ttgctttaaa aatctgcttg tgtactttat tatacatctc aatttagact 23101 agccacattt caggtgctca ttagccacat gtggctagtg gctactattg gtcagcacag

23161 attttttttt tttgacaggg tctccttttt tgtccaggtt ggggtgcagt ggtgcaatca

23221 tggctcactg tagtgtcacc ctcccaagct caagtgattt tcccacctca gcctcccaag

23281 tagctgtgat tacaggcgca tgccaccaca cctggctaag ttttaaaaat tttttgtaga

23341 gacagaggtc tgactgtgtt gcccaggctg gactcaaact cctgggctca agcaatcctc

23401 gtgttttggc ctcccaaact gctgggatta caggcatgag ccactgtgcc cagctagcac

23461 agatctttac tgtaactttt cttcttacta taaaaagcat tgcgttatac tggcaattat

23521 tttcccatca aagtggccta gaaaagagac atgaatctgg cctcatgtct ttgctcataa

23581 ttaacacatt tctagagaga tttcctttgt tagaaaaact aattgtggga ttaatgatct

23641 cagaacgtga attcaactgt agcacctaaa caggtgctac tgaagtcacc taaacagcag

23701 gctgaattct tgaccaatag tgataaaaac tgctttgtct tatggtagga gtagcagtca

23761 ggacaagact cagcatttag cgaaatccct ggagggattc tcccacatag gagccgtgca

23821 actcagtttt atgctcctaa aatctactgc aaagctgtga atgctttttg tttgtgattt

23881 gcacttcatt tttttcttct caattattat tattttttga gacagggtct tgctctacta

23941 gtccagagta caagtggtgc aatcatggct cactacggcc ttgacctccc agggtcaagt

24001 gatcctccca cttcggcctc ccaagtagtt gggaccacag gtgtgtgcca ctatgcatgg

24061 caatttttat ttttattttt gtagagacgg ggttctgctg tgttgcccaa gttggtcttg

24121 aactcctgga ctcaagtaat ctacctgcct tagcctccca aagtgttggg attacaggcg

24181 tgagccaccg tgcctggcca gaaaggtgat tttttaggat tctagcttgt ttgctttcct

24241 tcccacccca agataacttt tgttatagca gcttgcctgc tttctgtttc atttttcacc

24301 ctgatttttc caggactcct caatcacttc caagtgttaa aggccattac tgattcttaa

24361 atgtagatgg ctatggctga atttcagcca ttgagggtcc atatgatcta ttctgccaca

24421 gtccttctca aacttcagtg tggatgtgaa tcacctgggg atcttgttaa gatgaaattt

24481 gggccaggca tagtggctca tgcctgtaat tccagtgatt ggggaggctg atgtaggagg

24541 atcagtagag gccaggagtt tgagaccagc ctaggcaaca tagtgagata ccttgtctct

24601 aaaaatatat atatatttaa aaaacaactt agacaggcat ggggttgcgt gcctgtagtc

24661 ccagttactc aggagactca aggcgggagg atcatttgag tccagatgtt gcaggctgca

24721 gtgagttatg atcacaccca ccactgcact ccagccttgg cgacagagtg agaccctgac

24781 ccttaagaag agagagagac agagagagag agagtgagac tgatttgatg cagtaggtct

24841 gagatgaaag tttgcatttt tcacagactc tcaggtaatg ttgatgactc tggtccagag

24901 accacgtaga gatctagtat atgatagcaa aatgctgctg tcttatacca gcctgcagca

24961 aagacattaa aaaaaatgta gtgaggtttt ccaccaagct aaaagtactt ttttgtttta

25021 tatatatttt tttaaattca gagatgattt cattactgcc tcttgctact acggcaatta

25081 caaatgatag ttattattaa tatttttaaa tgacctttca tggcaaaatt atacagctgc

25141 caaccctact tatgtctcca agttaataaa agaattttag tagttcacaa actcctcaag

25201 tctgatgcca ccccaccatc taaattagca gtttatagct ttccttcatg gcatttatag

25261 tattttgtat tgacataatt acttggacag ttgtttaatg tcactttccc cactgtgctc

25321 taagctcttg ctctgtattt ttaatcactt tgtccctagt gtctcactag cactgggtct

25381 ggtgtctgtc tgtccctagt caatactttt aggatgcctt tattcagtgg gtctcagtag

25441 gagtggtact gccctctaat ggagtgtttt ggaaattgat gggaactact ggttgtccca

25501 aataatgaag tgtgctactg gtgtttggtg ggcaggggtt aaagggtgcc agacattctg

25561 tagtgtacag aacagctaac taagtgaatg cttatttgat gccttttgca aaatctttga

25621 atgtccatgt tggagattca attgatgaaa aacctatttg taattaccta aaccaaaaac

25681 ctaacttggc tgggtgcggt ggctcacacc tgtaatctca gtcctttggg aggccgaggt

25741 gggtggatca cttgaggccg ggagttggag accagcctga ccaacatggt gaaaccccat

25801 ttctattaaa aatacaaaaa ttagccaggc gtggtggcgt gcgcctgtaa tcacatctgc

25861 ttgggaagct gaggcacaag aatcacttaa gcctgggagg cagaggttgc agtgagccaa

25921 gatagcggcc aagatagtgc tactgcactc cagcctgggc aacagaacga gacactgtct

25981 caaacaaaac aaaacaaaac aaaacaaaac aaaacaaaac aaaacaaaac accacacaca

26041 aaaccacaaa aaacaaaaca aaaacccaac tccatttaac atttaaagac aactatattt

26101 atgtatgtcc agttttaata cacatacagt catgcatcac taatgatggg ggcacattct

26161 gagaaatgtg tcatgaggca gcttttttgt tgtacagaca tcatagagta tatttacaca

26221 cacctagatg gtatagccta ttgcacacct aagctatatg gtatagccta ttgttcctgg

26281 gctgcctgta tagtatgtta ctgtaggtag ttgtaacaca atggtaagta cttgtgtatc

26341 taaacatagg aaaggtatag ttaaaatatg ataatataat cttatgggac cagaattata

26401 tatgaagttt ttgttgactg aaatgtcatt atgcaacaca tgactgtatt ctgaaatttt

26461 cagaaatgca gctgctgagt acttcaaaag ttgtactttg acttattagc aacattacaa

26521 agtaacgtct accattctgg caaatcccat ccttagtagc agtgatgttt gtggtatttg

26581 aattattatg tatataactg cactaataca cgtttgtagg aaatatgatg gttatgtata

26641 tgtgtgtgtg tacatacaaa tttagccctt attctaaatt atccaataaa aattgttgag

26701 aatattcagg tgaatttttt ttactttttt aaaatccaaa tttacccatt aaaagtggtt

26761 gcaagcatct cactacatca ttaaatcatt tggtggtgtt atctctgagt atttacatct

26821 tggggtgtgt atgtgtgtgt gtgtgtgtgt gtgtgtgtgt acctaaa,tca cacatatgaa

26881 agacaataaa agttaatctc ttttattttc tttttatatt acattttgga ctttatgttg

26941 tttttctttc tctgcatgca taccatctct gtatattaca aacacttact atcaaaaggt

27001 ggtggtactc tgataggatt cagaaccccc cttctcatgg aagcagcatg gaatcaagga 27061 tttctgcctt ctggtcttgg tttatttctc taagctgctc acataacttt tctgaatttg 27121 ttgggtgatc tacattatca ctgataaggt aagtcatgat gtgataagtc acagcagatg 27181 tttcatgaat gactggacat gtagaaaatg ccttgcttac atggtgactc ttagccaggg 27241 ctcctcagaa aggcagactg tccacctgag acccaccgtt ctgcttcact tgcattttca 27301 tttagggaga gcagaccacc ttggaggaag ggatttggct aatgataagg tatgaggtag 27361 agtggggaag tatggtagtg gtggggtagt attaatgagt gaataaaagc agagtatgtt 27421 ttacctttct gggaagcagt taagatcctt agactagggg ccactattgt aaggattttt 27481 tgacagttcc atgtttatct gtttcttagt gattaacaac caaacccatg aagacttata 27541 gactggggag acttttgtgt cttgttcagc agttggtttg gagtggacca caaagctcag 27601 aggcaaaaga gtagtgcaca gtgtacacag ttggtactaa gaaaggccct cggggactgg 27661 gttacgaggt ttcgcagcag aaagtccctt caagcacatg attttagtct gcctagatct 27721 ggctagaatg ttgctcatta attggagcta gaaagataca ggaagctcaa gggtaaatgg 27781 cactggaaaa aggtcactga aggtgaatcc atttaagatg aagatcaagg aactagtgca 27841 tggctgccat gttgcagcag gacagtaatg atgacactga aggtgtttca cccttcaatg 27901 cagaagagaa gacaacttag tagaccaaaa atgcttctca gaatagggga ttaaaaacaa 27961 tagaccaaaa aaaaattaga cacccaatag cgtaattttt ctgtttactc ttttgagtgc 28021 atgcagttat aatccatctt ctctgtgaat tgctcagcag cagctatact gcgtggatgg 28081 tgacagttct cttgttgcca tgtgatttgg gggcagtgaa gactgtcaca ggtagactga 28141 tggtggacct gcattggtgg aatcatactg atgaagatga gaagaaccac tgggtgtcca 28201 ggaagagcca ctgggagtcc aggaaggcat cccctcaaga taacaaaact gtctcagagg 28261 ctgaatcaag gatcttttgg ttgggattta ttgcctgttc agtgctgtgg gtggtaattg 28321 cctttagtgc cctcttcttt tttggagtaa agtgattggc agtggttatc atgggtgtgg 28381 cgctgcaaga tgccaaccta tatggttaca tcaggtataa agttggcagt agaaggaatt 28441 taaccagcat ggctatcttg tagcctggaa agcagttttt aagacaaaac agtaaagata 28501 atctgacttc cagactagag agaatgctct tatatctttt attatactgg ggaatgaaga 28561 catttttgac accgaacctt ttagtgccca gtccatgttg taatgaggag tgttggctct 28621 atttttccac ttaaaagctt tacttgtttt aaaaaaggaa aattagtttt tatacttttt 28681 attttctttc cagtagttgg ggctagaaaa tatgttgtca ctagaaacat tgtgaaaatt 28741 tgtcttacag gctgggcacg gtggctcaca cctgtaatcc cagacctttg ggaagccgag 28801 gtgggcggat cacctgaggt caggaattcg agaccagcct ggccaacatg acgaaacccc 28861 atctctacta aaaatacaga aattagctgg gtgtggtggc acatgcctgt agtctgtagt 28921 ctcagccact cgggagactg aggcaggaga attgcttgaa tctgggaggt ggaggttgca 28981 gtaagccgag actgtgctac tacgctccag cctgggcgac aaagcgagat tctgtctcaa 29041 aaaaaaaaaa aaattgtttt gcagtgtaca taggtatgca catagtcata taatatcaat 29101 atgtcccaaa ttaatgaaaa tgtgttcatt tacgtaagta tggagacttt tgcattttga 29161 ttcatagaac atgagaggat gttagtctgt ctcaaaactc tgtatgttta catattattt 29221 atgttgacta ttttcagaag taaattttgc ttccatgata aaagtgagca ttttggctta 29281 tgcgtaagtt agaaataatt attaattttt aatatgtacc tcatggtaaa atttcttaga 29341 tatatgcaaa caattaaaaa ccaaatttgg gtcagtggtg ttaactagtt tctgaaattt 29401 tgtttatttt tatttgtaac aattcattga cttaaggccc aattaataca aatggaatca 29461 ccatagttta tgtttaagga atacacagag attgctactg ttccatttat tttacggtaa 29521 ggatagacaa attttacctt ggagcttcct acaagctgtt cagtgttcct tgagcgaata 29581 aaatctatct tttgtctcta aaagagcatt attcatatgt cataatgaca gtaatcattt 29641 aaatacttgg cataataaat gcctaaaaga cattttattt tataaatctt tttttttctt 29701 tctatgatgg gtatattgta aatcatgcat ttgtattaat ggtatttctt aaagcagtag 29761 atgtaactgt aaactaaatc agtctacaaa ctattctagg cacccataga ttctgttgta 29821 ggtactgtaa actttgttgg agactttagt cggcagatta tgttgtgaat atatttgtac 29881 tttgttaaaa tattttaaaa gatgtttaat tgaatacgtg tcttttttgg actagtagct 29941 gtgaaggtat aaaactttat atttgtataa aattgctgtt tatagagcaa aagaaaatga 30001 agatcaaaaa tttatggtta atatgcatag aaagtttgat tagaattgag tctttttgtt 30061 tcttttatga ttttcttttt tttaattatt attatacttt aagttttagg gtacatgtgc 30121 acaatgtgca ggttagttac atatgtataa atgtgccatg ttggggtgct gcacccatta 30181 actcatcatt tagcattagg tatatctcct aatgctgtcc ctcccccctc cccccacccc 30241 acagcagtcc ccagagtgtg atgttcccct tcctgtgtcc atgtgttctc attgttcaat 30301 tcccatctat gagtgagaac atgcagtgtt tggttttttg tccttgcgat agtttactga 30361 gaatgatttc caatttcatc catgtcccta caaaggacat gaactcatca ttttttatgg 30421 ctgcatagta ttccatggtg tatatgtgcc acattttctt aatccagtct atcattgttg 30481 gacatttggg ttggttccaa gtctttgcta ttgtgaatag tgcctcagta aacatacgtg 30541 tgcatgtgtc tttatagcag cacgatttat agtcctttgg gtatataccc agtaatggga 30601 tggctgggtc aaatggtatt tctagttcta gatccctgag gaatcgccac actgacttcc 30661 acaatggttg aactagttta cagtcccacc aacagtgtaa aagtgttcct atttgtccac 30721 atcctctcca gcacctgttg tttcctgact ttttaatgat tgccattcta actggtgtga 30781 gatggtatct cattgtggtt ttgatttgca tctctctgat ggccagtgat gatgagcatt 30841 ttttcatgtg tcttttggct gcataaatgt cttcttttga gaagtgtctg ttcatgtcct 30901 ttgcccactt tttgatgggg ttgtttgttt ttttcttgta aatgtgttgg agttcattgt 30961 agattctgga tattagccct ttgtcagatg agtaggttgt gaaaattttc tcccattttg 31021 taggttgcct gttcactctg atggtagttt cttttgctgt gcagaagctc tttagtttaa 31081 ttagatccca tttgtcaatt ttggcttttg ttgccattgc ttttggtgtt ttagacacga 31141 agtccttgcc catgcctatg tcctgactgg taatgcctag gttttcttct agggttttta 31201 tggtttgagg tctaacatgt aagtctttaa tccatcttga attaattttt gtataaggtg 31261 taaggaaggg atccagtttc agctttctac agatggctag ccagttttcc caacaccatt 31321 tattaaatag ggaatccttt ccccattgct tgtttttctc aggtctgtca aagatcagat 31381 agttgtagat atgtggtgtt atttctgagg gctctgttct gttccattga tctatatctc 31441 tgttttggta ccagtaccat gctgttttgg ttactgtagc cttgtagtat agtttgaagt 31501 caggtattgt gatgcctcca gctttgttct tttgtcttag gattgacttg gcaatgcggg 31561 ctcttttttg gttccatatg aactttaaag tagttttttc caattctgtg aagaaagtca 31621 ttggtagctt gatggggatg gcattgaatc tataaattac cttgggcagt atggccgttt 31681 tcacgatatt gattcttcct atccatgagc atggaatatt cttccatttg tttgtatcct 31741 cttttatttc attgagcagt ggtttgtagt tctccttgaa gaggtccttc acgtcccttg 31801 taagttggat tcctagatat tttattctct ttgaagcaat tgtgaatggg agttcactca 31861 tgatttggct ctctgtttgt ctgttactga tgtataagaa tgcttgtgat ttttgtacat 31921 tgattttgta tcctgagact ttgctgaagt tgcttatcag cttaaggaga ttttgggctg 31981 agacaatggg gttttctaga tatacaatca tgtcatctgc aaacagggac aatttgactt 32041 cctcttttcc taattgaata cactttattt ccttctcctg cctaattgcc ctggccagaa 32101 cttccaacac tatgttgaat aggagtggtg agagagggca tccctgtctt gtgccagttt 32161 tcaaatggaa tggttccagt ttttgcccat tcagtatgat attggctgtg ggtttgtcat 32221 agatagctct tattattttg aaatacgtcc catcaatacc tgatttattg agagttttta 32281 gcatgaaggt tattgaattt tgtcaaaggc cttttcggca tctattgaga taatcatgtg 32341 atttttgtca ttggttctgt ttatatactg gattacattt attgatttgc atatattgaa 32401 ccagccttgc atcccaggga tgaagcccac ttgatcatgg tggataagct ttttgatgtg 32461 ctgctggatt cagtttgcca gtattttatt gaggattttt gcatcaatgt tcatcaagga 32521 tattggtcta aaattctctt ttttggttgt atctctgccc agctttggta tcaggatgat 32581 gctggcctca taaaatgagt tagggaggat tccctctttt tctgttgatt ggaatagttt 32641 cagaaggaat ggtaccagtt cctccttgta cctgtggtgg aattcagcta tgaatccatc 32701 tggtcctgga ctctttttgg ttggtaagct attgattatt gccgcaattt tggatcctgt 32761 tattagtcta ttcagagatt caacttcttc ctggtttagt cttgggagag tgtatgtgtc 32821 gaggaattta tccatttctt ctagattttc tagtttattt gcatagaggt gtttgtagta 32881 ttctctgatg gtagtttgta tttctgtggg atcggtggtg atatcccctt tatcattttt 32941 tattgcgtct atttgattct tctctctttt tttctttatt agccttgcta gcggtctatc 33001 aattttgttg atcctttcaa aaaaccagct tctggattca ttaatttttt aaagggtttt 33061 cttggtctct atttccttca gttctgctct gattttagtt atttcttgcc ttctgctagc 33121 ttttgaatgt gtttgctctt gcttttctag ttgttttaat tgtgatgtta gggtgtcaat 33181 tttggatctt tcctgctttc tcttgtgggc atttagtgct ataaatttcc ctctacacac 33241 tgctttgaat gtgtcccaga gattctggta tgttgtgtct ttgttcttgt tggtttcaaa 33301 gaacatcttt atttctgcct tcatttcgtt atgtaccctg tagtcattca ggagcaggtt 33361 gttcagtttc catgtagttg agcggttttg agtgagtttc ttaatcctga gttctagttt 33421 gattgcactg tggtctgaga gatagtttgt tataatttct gttcttttac atttgctgag 33481 gagtgcttta cttccaagta tgtggtcaat tttggaatag gtgtggtgtg gtgctgcaaa 33541 aaatgtatat tctgttgatt tggggtggag agttctgtag atgtctatta ggtccacttg 33601 gtgcagagct gagttcaatt cctgggtatc cttgttaact ttctgtctcg ttgatctgtc 33661 taatgttgac agtggggtgt taaagtctcc cattattatt gtgtgggagt ctaagtctct 33721 ttgtaggtcc taaggacttg ctttatgaat ctgggtgctc ctgtattggg tgcatatata 33781 tttaggatag ttagctgctc ttgttgaatt gatccgttta ccattatgta atggccttct 33841 ttgtctcttt tgatctttgt tggtttaaag tctgttttat cagagactag gattgcaacc 33901 cctgcctttt tttgttttcc atttgcttgg tagatcttca tccttttatt ttgagcctat 33961 gtgtgtctct gaacgtgaga tgggtttcct gaatacaaca cactgatggg tctggactct 34021 gtatccaatt tgccagtctg tgtcttttaa ttggagcatt tagtccattt acatttaaag 34081 ttaatattgt tatgtgtgaa tttgatcctg ccattatgat gttagctggt tattttgctc 34141 gttagttgat gcagtttctt cctagtcctg atggtcttta cattttggca tgattttgca 34201 gcagctggta ctggttgtgc ctttccatgt tttgtgcttc cttcgggagc tcttttaggg 34261 taggcctggt ggtgacaaaa tctctcatca tttgcttgtc tgtaaagtat tttatttctt 34321 cttcacttat gaaggttagt ttggctggat atgaaattct gggttgaaaa tttttttctt 34381 taagaatgtt gaatattggc ccccactctc ttctggcttt tagagtttct gccgagagat 34441 ccgctgttag tctgatgggc ttccctttgt gggtaacctg acctttgtct ctggctgccc 34501 ttaacatttt ttccttcatt tcaacttttg tgaatctgac aattatgtgt cttggagttg 34561 ctcttctcca ggagtatctt tgtggcgttc tctgtatttc ctgaatctga acgttggcct 34621 gccttgctag attggggaag ttctcctgga taatatcctg cagagtgttt tccaacttgg 34681 ttatattctc ctcgtcactt tcaggtacac caatcagacg tagatttggt cttttcacat 34741 aatcccatat ttcttggagg ctttgttcgt ttctttttat tcttttttct ctaaacttcc 34801 cttctcgctt catttcattc atttcatctt ccatcactgg taccctttct tccagttgat 34861 cgcatcggct cctgaggctt ctgcattctt cacgtagttc tcgagccttg gctttcaggt 34921 ccatcagctc ctttaagcac ttctctgtat tggttattct agttatacat tcatctaaat 34981 ttttttcaaa gttttcaact tctttgcctt tggtttgaat ttcctcctgt agctcggagt

35041 aatttgatcg tctgaagcct tcttctctca actcgtcaaa gtcattctcc ttccagcttt

35101 gatctgttgc tggtgaggaa ctgcgttcct ttggaggagg agaggtgctc tgcttagagt

35161 ttccagtttt tctgctctgt tttttcccca tctttgtggt tttatctact tttggtcttt

35221 gatgatggtg atgtacagat gggtttttgg tgtggatgtc ctttctgttt gttagttttc

35281 cttctaacag acaggaccct cagctgcagg tctgttggag tttgctagag gtccactcca

35341 gaccctgttt gcctgggtat cagcagtggt gtctgcagaa ccgcagattt tcgtgttaca

35401 tgaatgctgc tgtctgatcg ttcctctgga agttttgtct cagaggagta cctggccgtg

35461 tgaggtgtca gtctgtacct actggggtgt gcctcccagt taggctgctc gggggtcagg

35521 ggtcagggac ccacttgagg aggcagtctg cccgttctca gatctccagc tgcgtgctgg

35581 gagaaccact gctctcctca aagctgtcag acagggacag aggttactgc tgtctttttg

35641 tttgtctgtg ccctgccccc agaggtggag cctacagagg caggcaggcc tccttgagct

35701 gtgttgggct ccacccagtt cgagcttccc ggctgctttg tttacctaag caagcctggg

35761 caatggcggg cgcccctccc ccagcctggc tgctaccttg cagtttgatc tcagactgct

35821 gtgctagcaa tcggcgagac tccgtgggcg taggaccctc cgagccaggt gcgggatata

35881 gtctcctgat gcgccggttt ttaagcccgt aggaaaagcg cagtattcgg gtgggagagg

35941 cctgattttc cacgtgctgt ctgtcacccc tttccttgac caggaaaggg aactccctga

36001 ccccttgtgc ttcccgagtg aggcagtgcc tcgccctgct tcagctggcg cacggtgcgc

36061 tgcacccact gtcctgtgcc cactgtctgg cactccctat tgatatgaac ccggtacctc

36121 agatggaaat gcagaaatca cccgtcttct gcgtggctca cgctgggagc tgtagaccgg

36181 agctgttcct attcggccat cttggctcct ccctctcttc cttatgttta ataactatca

36241 cagtaaacac gctttttgtt taatattaat aatgataatt aatctagaag aaaaatatta

36301 aagcctagag ttttgtggtc acaggaaatc atagccattt aaaaatttta aagtatgtat

36361 gaaattttat gatgcagaga aatatgatgg agtatttgta agtcggtaaa agactttaag

36421 cataaatgta tttatttcat taggttgaaa tttggatgga gaggaggaat gaaatatggt

36481 ttcaaagagg aaagcataca atgtaaattt taaaagtctt gttaatgtat gttttatatg

36541 gattatggtg ggaataaaat atgatattta ggtttctctg gatacattta aaagaataat

36601 attaagaaag tgaaaagata ggcctctgtg gtttgatctg tgagatcatc agagtgttct

36661 aaagttgatt ttgtggctgt ttggcacaac tctaaaaaac cattgaaagc ctctgtggct

36721 tatcttttca ctttcttaat attattcttt taaatgtatc cagagaaata aaaattttac

36781 aaatcacata cctgataagg gactggtatc ccagaatata taaagaactc ttacaactca

36841 ataataaaag acaacccaat taaaattctt ggcaaaggat ctgaacagat gtttcttcaa

36901 agaggatata cacatggcca ataaacatat gaaaaggtgt tgaactttat tagccatcag

36961 ggaaattcaa atcaaaacca tcacgagcta ccacttcaca gggaaattaa aatcaaaata

37021 atgatgagct atctaggatg gcctgaagaa aaaaacaaaa acaaaaacag gtaattgcaa

37081 atgttggtga ggatgtgaat aattggaact ctcataccct gggactgcaa aatgattcac

37141 ctgctttgga aaacagtctg tagttcctca aatagttaaa catagaatta tgacatgatc

37201 cagtaattcc actccaaagt atatacccga gagaaatgaa aacgtgtcga cacagaaact

37261 tttgcaccaa aggacagagc agcattgttc ataatagcca aaatgtggga acaatcccaa

37321 tgtccatcat ctgatgaatg gataaagtgc agcatatcta tataatgaaa tgttattcat

37381 taatagacag aaatgaagta ctgatagatg ctgcaacatg agtgaacttt gataacatta

37441 tgttaagtga aagaagctag tcacaaagga ccacatattg tatgattctg tttatatgaa

37501 atgtccaaaa taggtaaatc tatagagaca gaaagtagat taatggttgc ttagggccga

37561 ggtggaagta gtggtgggga ggagatgatg gggtggggtg ggggattgac agctgtggct

37621 ctctttgaga tcatcaaagt ggattttgtt gagatcatca aaatggattt tgttgatgtt

37681 tggcacaact ctgtaaatat actaaaaacc atttttatta gttcattttc acactgctga

37741 tgaagatata ccctagactg ggcaatttac aaaagaaaaa ggtttaatgg acttacagtt

37801 ccacgtggct ggggaggcct cacaatcatg gcagaaggtg aaaggcacat ctcacatggt

37861 ggcagacaag agagagagct tgtgcaggaa aactcccatt tttaaaacca tcagatcttg

37921 tgagacttac tcactatcat gagaacagca agggaaaaac ctgcctccct gattcagtta 37981 tctcccactg gctccctccc acaacacatg ggaattatgg gagctacaag atgagatttg 38041 agtggggacg cagagccaaa ccatatcacc attgaactgt acacttcaaa tgagtgaatt 38101 gtatagtatg taattatacc tcaagcggtt taaagaaata atgtaatagt ttcattttta 38161 agagtctgtg tttacaatat gccagaaatg acatactttg cattctcaaa tacacatgtg 38221 atgaactgtt gcacatatca ccttaaacat ttaaaaaaat gcagtcttaa attaccagtt 38281 ttaatggttg cataatattt cagtaagtta atgtgggata ctttgctcat tttcccccta 38341 tataagtact ttctcatatt ttgatgtttt aaatatgaat ttctatacct gctaattttc 38401 ttcttttgct actttctttg gataaaattc tgactgacac tcagaaaaaa tgaatagata 38461 gcaagagttt ttttttaatt aaatttttat ttttttattt tttatagaga cagggtttcg 38521 ccatgttggc caggctgata tcaaactcct ggcctcaagt gatctgcctg ccttggcctc 38581 ccaaagtgct gggattacag gcctgagcca ctgtgcctag catgaattgg gattgctgag

38641 atttcttgca taggtattgc catgttactt tctgaagggt tgaaccaatt tttctcattt 38701 acattttttt tttactgtta actatataat ttgttccaca gtaaacgttt aaaggtgtat 38761 ttctttgagt atcaaagtaa attattgtta aacctccatt tgtttcctat tactgccttg 38821 agagtgatga aagttattta ttaaatgaac tcatactgaa tacccactct gtgtcaaaac 38881 ttgtaccaga tactggagac tggagatgca aagtgagaaa ggcttagttt cgcactcaga 38941 aaagttccac atctcgtggg gaaataatta cagtaggtaa catgaaggcg tcaagtatga

39001 aaaggtgttt gaggaggcac ctggaggttg tggccagcat aggaggggag gtgatatgta

39061 tgtacagctc aaaagatgag cagacctttg cctggaggca agatgaggac aaagagaggg

39121 cattcctggt gcaattacac acacagcctc caaacacagt gatctgggca agcagttccc

39181 acaggttccc tttgactgaa gagttgtcgg cttttttgtg tttctaattt attcattagt

39241 acatttggtt gttttctttg tttttgataa tatgctctgt tctttgcatt ccatacacat

39301 attaatagta atgttaaatg ttacttttaa gacaaatatt tccttttagt ctgtcctttg

39361 actttttatt tttcatcata tttttacatt ctgggattgt gatgatttgt tttgatatac

39421 accatatgga aatttcttaa tttataacat tatggattta gctggtccag tagtagcaaa

39481 gccttgtttc ttaaggtggt tttcccgcta agtatgagaa gagttgtaaa atatatgtgg

39541 ggcccttatt tctcatgccc aagctctttc tgtgtcgaac cgctttataa taatacagcg

39601 tgacgttaac ttgatggctg agttaggaag ccagatgaca gcttctcttt atttactgtc

39661 ttctcagggt agaatggctt cattcacttg atctgaagag ccaagccaac agccctactc

39721 tgggcctcca caggtctgtg gcagcagtaa attgaaaaac ctgttcacat ctcaacagcc

39781 tcaaattttt atttttttag caatatagta gatagtaagg agtgaaacga tataaatcag

39841 atggaaaggg aattggtatg gactgaattg tttctccctt caaaattcgt atattgaagc

39901 gccagtctcc aatgtgactg tatttatgga taaggccttt atggaagtag ttaaaattaa

39961 atgagatcat aagagtaggg ccctgatcta attgggttaa tgtccttatg ttgaagagat

40021 aacagagaac tctctctccc tctactccgt gtgagtatac agcaggaagg cagacatctg

40081 caagctagga aaagggtcct gaccaggaac caaaccctgc tggaccttga tcttggactt

40141 tccagtcccc aaaactaaga aaatcagttt cggttgttta agtcaaccag tccatggtat

40201 tttattattg cagcctgagc agacgaaaac agtcataatg ataataacca aaacaattat

40261 ttattaccta acatatatcc attttggatt cccttaaagc caagtatgag ttaagtcata

40321 tctttatctc cgttttcctg atgggtaatc taatcattaa gtaacttcct tcaggtctca

40381 gtgccgggaa ggtgaatctg tggatccttg ttgagcttat gtctaattta ggtaacagct

40441 ctatgtaatt catttatata tttgagagga aaagagactc aacagcaacc acaagtagac

40501 tacaaactcc tgcacaaata tgtttgggaa actcacatcc tcttcttagt ggatatgcgt

40561 ttaatattca agactctgtg aaatcctaca cggaagaaac ctgtttaact ttactttatc

40621 agaatacttc taggggcacc tctggtgata ccatgggtaa caatgtttct tggacatcag

40681 tttgggaagt gcagcccaga gtggtcatta gattcctgca ctcgccacca taggcctatt

40741 caatttgaaa catacttaaa tgttgatgag catgcatgct tattacaatt tattgaacta

40801 aaaaatgtaa tgagaatata catatatgtt acttcaagaa attcagtcga atttagcttt

40861 tctttttgca taaagattag acaaaacctt aaggtagatg gttatgaatt ttagacatct

40921 taccgctaag aaaagaaagt agatggctct ataaaagtaa gcttttttat tattatttta

40981 gtgagcacca aatgtggtag acatttctgt agggcagaaa ggatgagagt tccagtctca

41041 tggaatttac attgtataga gatgtggaga ttaagggtta catgtgttct tctcaacatg

41101 tttatatatg tatatatatt ttacacatta ttgtagttgg aaggtttttt gcacattgtg

41161 gccttggcca ctcat'aaata catcctcagt ttttttcagg tattaatatt ttgattatgg

41221 aaacggactt tgggcctatg cttggcttac aatgtttcag tccacaaatg aatcttattt

41281 ttaattattg aatgaatgat ttctctttaa ataaccttaa aatgatttaa aatctctaaa

41341 gagacttgtt agttttatcc ttttttttcc cccgtaactc aaaagcagtt ttaaaaaatc

41401 tacacatttg ccaggcttga attgaaaaca tttgagcatc tgagtgaagg tgttggtgaa

41461 gttggttgac ggtttttttc tttaatctca tgataacatc acttaaataa tttataagaa

41521 aaatcctggg tattttcctc cttttttttt agagatgaga tctcactctg tcatcagtct

41581 tttaaaagta ggtcctacta catacttgat aacacttaaa atgaatgttt ttagacagtt

41641 ataatttatt tatagttaga tgaaccaaac agcctttaac ttctgttgct aaagcaagcc

41701 cacttcaaga tacaaaagat tttccatctt taacatattg gccaaaggag aaaaagagaa

41761 aaaagaacgt tgaaaatgtg ttgtcctact tcattttccc ttctgtgtca cacacagtga

41821 gaataattaa cagccactta gtagatttct tttaagcaga tcactgatct gggaagtgct

41881 cacttagtct cagaaaggat ttggtcagtg gagaagaaaa tcacaactga catttatggg

41941 tggagtctgt gggcaggagc agccagcttt ttgacagcag ttgtgagctc tgggtaactc

42001 ccaccagtta gtgaaattaa tgccaacttc tttttgtttc tttagccttg ccactgtttg

42061 cctaaacatt caaagaaagg cagtaattcc atcatatttc ttgattcaca aagcttaagg

42121 gcaggcagga ggatgttcat cttatggaag cctccggttg ttgagttagt gttttgcatt

42181 aagatggcaa gagaaagctg ttgttgctta attagtgaga ggcatactga cagtatgaag

42241 gacttttttt ttttttttta attctgctgg aggtgatttt taatggttca gcgtgcatgt

42301 gagtattcta agcccaaagc cagaccctgg ttcctttgat ggactgcttg caaattagtt

42361 gaaaagtagc tataacttaa gcctttattc ttttctcttg ttctttttcc ccattaagct

42421 ttccccctca cttaaaaaat aaaaatataa catatgcata tcaaacaaaa gagcataaaa

42481 taaaaagttt tcctcatgct cccaagtctc tggttaccct ttttagagat aactatgaac

42541 agcattttaa aaactgcttc cagacatttt ctttgcctat gggtctcttc cccaccttgg

42601 gctccacact agtggagctt ttcttcttag caatgtatat tgaagagtgt tttatatcag

42661 catgtatata gatccaactc attctgttca taggttgcat gctattcatc gtatggatgt

42721 actataattt atttacctgt ttttaaaaat tggtgaacat ttaggttgtt tattgggttt

42781 tattcttaca aacagatgaa tggatagttt tgttaacaac taaatattga gtcacatatg

42841 gtaatataca tttaaaatta taatactata tatattgcca aaattgcctg atgaactgac 42901 tcacaccctc atctgaaatg tctgtttttc cacctttacc cttgttgcat tttctgaagc 42961 ttgcaatctg gaacatgaaa atatatgctt tactagttat tttaaattta cattacttta 43021 attattagtg aggctgagca tattttcttt ttatgtttat aagccattaa attatttttt 43081 cttgtgaact ataggctgct ttcaacactt agttatacct gatgagaatt actgtacagg 43141 tttgggagga catccagaga cttgtagaac cgtcttagtg tgttaggaac cttgaagacg 43201 atctagtccc accttccaat tggtataaaa aatattttta taacctctgt gactggttct 43261 ttgattatct gcttaaatgc tttcaatatt agaacaatct tagggggcct gaccttgctt 43321 ggctttgctt gctttacaat gtttcagtct ataagtgaat cttatttcta attattaaaa 43381 gaatgatttc actttaagta cgttaaaatg atttaaaatc tctaaagaga ctggttagtt 43441 ttattttttt atcttttttt ttttcctcct gtaactcaaa agcagttttg agtgaaggtg 43501 ttggtaaagt tgtttggcga gttaaaactt catgggcaac taattcctct tttggcttta 43561 gttgacagaa atttcaagat atgttaaaag agtatttgaa tagataggga aggtgggagc 43621 agctgaactc tttaaataaa ttgctacatt aagccaggtg cagtagctca tgcctgtaat 43681 cccaattact tgggaggctg aggctggatg atcacttgag cccaggagtt cgaggctgca 43741 gtgagctatg gttgcaccac tgcactccag cctggacaac agagtgagat cctgtattaa 43801 aaaaatagat aagaaataaa tacatgacat ttatgaagct agaagattgt ttcaggtcca 43861 gtcaggggat caggagcaat gcatgtttac tgaatcttgt ccttttgact aagaatgaga 43921 gaatttataa ttgaagaggg tcctttgagg gtatgttagt tatctattgc tgcataataa 43981 attactccta aacttcatgc cttagtgcct aaacaacaat aaacatctgt tctctcacag 44041 agtttctgtg ggttagcaat ttgggagcaa cctagctggg tggtttaggc tctgggtgtc 44101 ttggaggttg cggtcaagat ggcggttgga gctgcattca tttgaagact tgactgggcc 44161 atgtggttct gcttgcacaa tgcctcactc acatgactgt tggcagaagg ttaaggaatg 44221 aggttccttg cctcatggac ctctctgtag ggttgcctga gtgtcttcac attctggtgg 44281 ctggtgtttt ctagagtgag taatccaagc aagggcaaaa tagaagccct tatgtgtttt 44341 aagacctcag aagtcacaca ttgtcatttc tgtaatatcc tattgcaggt gcagtatcca 44401 cacaggtcag tcctattggt atgggagggg gctacacaga agagtgaata ctaggaggca 44461 aggatcagtg gggcctttct agggaatgac taccttctgg cccctagaga ttcagatctc 44521 acccacctgg gaaacaaaac atactcactt ctctcagggc ccccagacct catcccagca 44581 ctgagcccaa ttctgtggag gagaattgga ggatatttaa acagatttgg ggaagctagg 44641 aatctattaa gaattttcct ttcttggaag aaatgttgga tttgggcagt gttttgaata 44701 ataaaagcat ttctttatgc cctgtcctat gaaacttctg gcccaaataa ataggaaata 44761 gatttataat cctgacagag gaatggtgtt ctagtgaaat attccaactt atttttattc 44821 agaaaagctt catagcattt gctagttctc aaatatgagg gttaggttct tggaaaacct 44881 gagaactgag agttctcagt tgagggactt gaaacctaat agggaaaata tggatagcaa 44941 actgtgctgg ctatttaatt gtggtttcaa cttcaacctc tccattttat actttgtttt 45001 gtgaggctgg ggttggaact ctgtaaatta tgcttcccag attcactgga tttccagttt 45061 gttcctggca gtaggagaca ctggtggaga actgaaatgc agtagggaga gaaaggactt 45121 tgctgttctc agctcctgtc actatttctc ctagagtcag caacagctct agcctatagt 45181 ttctttcttt ctttctttct ttctttcttt ctttctttct ttctttcttt ctttctttct 45241 ttctttcttt ctttccttcc ttccttcctt ccttccttcc ttccttcctt ccttccttcc 45301 ttccttcctt tccttccttc cttccttcct tccttccttc tttctttctt tctttctttc 45361 tttccttctt tctttctctt tccttccttc tttccttctt tatttctctt tctttttttt 45421 taattaaagt tctagggtac gtgtgcacaa catgcaggtt tgttacatag atgtacatgt 45481 gccatgttgg tttgctgcat ccattaactc gtcatttaca ttaggtattt ctcctaatgc 45541 tctccctccc cctgcacccc atcccacaac atgccctggc gagtgatgtt ccccgccctg 45601 tgtccaagtg ttctcattgt tcacttccca cctgtgagtg agaacatgca gtgtttggtt 45661 ttctgtcctt gtggtagttt gctgagaatg atggtttcca gcttcatcca tgtccctgca 45721 aaggacgtga actcatcctt ttttatggct gcatagtatt ccatggtgta tatgtgccac 45781 attttcttaa tccagtctat cattgatgga catttgggtt ggttccaagt ctgctattgt 45841 gaatagtggt gcggtaaaca tacatatgca tgtgtcttta tagtagcatg atttataatc 45901 ctttgggtgt ttacccagta atgagatcac tgggtcaaaa ggtatttcta gttctagatc 45961 cttgaggaat caccacactg tcttccacaa tggttgaact aatttacact cccaccaaca 46021 gtgtaaaagt ctacttattt ctccacagcc tctccagcat ctgttgtttc ctgacatttt 46081 aatgatcacc attctaactg gcgtgagatg gtatctcatt gtggttttga tttgcatttc 46141 tctgatgacc agtgatgatg agcattcttt catgtgtcta ttggctgcat aatgtcttct 46201 tttgagtagt gtctgttcat gtcctttgcc cactttttga cggggtcgtt tgtttttttc 46261 ttgtaaattt gtttaagttc tttgtagatt ctggatatta gccctttgtc agatgggtag 46321 attgcaaaat ttttctccca ttctggaggt tgccttttca ctctgatggt agtttctttt 46381 gctgtgcaga agctctttag tttaattaga tcccatttgt caattttggc ttttgttgcc 46441 attgctttgg tgttttagtc atgaagtctt tgcctaggcc tacgtcctga atggtattgc 46501 ctaggttttc ttctagggtt tttatggttt taggtctaac atttaagtct ttaatccatc 46561 ttgaattaat ttttgtgtaa ggtgtaagga agggatccag tttcagcttt ctacatatgg 46621 ctagccagtt ttcccagcac catttattaa atagggaatc ctttccccat tgcttatttt 46681 tgtcaggttt gtcaaagatc aaattgttgt agatgtgtgg tgttatttct gaggcctctg 46741 ttgtgttcca ttagtctata tatctgtttt ggtaccactg ctatgctgtt ttgttactgt 46801 agccttgtag tatagtttga agtcaggtat tgtgatgcct ccagctttgt tcttttggct 46861 taggattgtc ttggcaatgc gggctctttt ttggttccat atgaaattta aagtagtttt

46921 ttccaattct gtgaagaaag tctttggtag cttgatgggg atggcattga atctataaat

46981 taccttgggc agtatggcca ttttcacaat actgattctt cctatccatg agcatggaat

47041 gttcttccat ttgtttgtgt cctcttttgt ttcattgagc agtggtttgt agttctcctt

47101 gaagaggtcc ttcacatccc ttgtaagttg gattcctagg tattttattc tctttgaagc

47161 aattgtgaat gggagttcac tcatgatttg tctagcctat agtttcttta ggaactcact

47221 gtgccaactt tactatggcc cctaaccaag atctaagtgg caattacact gtgtgcccca

47281 ccccccattc ccccagttcc acttaaggtt ctaataccga tccctccttt gagcacccag

47341 atgctggtaa ctccacatct ccctttgtgt ttcttcaccc ctaaggttgg tttctgcttc

47401 tagcagttac taatattggg gttgcctctg tgaccccttt ttattttttt aagtctctta

47461 acacctgtat aatcagcttc ctgtattaaa ttccttccat ttaaaataca taatgtgtga

47521 ggcttctgct ttccattgag tggaacagtt attaaggttt ctggatatgt cacccctcac

47581 aattacagtg acatgtttgt agttaatttt tctttcttgc caggtgacag tcataccaag

47641 aggccactgt cttctccatc tggtcctttg ttcaaatgtt tagtgatttt ttttttcatt

47701 tttttaatgc tcgtagccat tgacttcatg gatctggcct cttagagcag gcctccagga

47761 tcctaattcc ttagtccgca gtggtcctag acatccaggt tatctgggat gttgagtagt

47821 ttggttcagt ctgtttaata caagtactta ttcctatgta ttttccaata caaaggagca

47881 tacactgtat aattttggct ttaccagttc ctgcttgcct gagtgcctgc tctttgagcc

47941 tcctttacac acttcccagt ggcctccatc ctcacagaca ctgctcacca gtgggcactt 48001 gcaggaccag cacttacttc ccctcatctt tctttatttt tcccaagact tttactactg 48061 ctctgtcatc tgctttgttt cccttttcta tttccaaacc ctaattccct cattttctta 48121 ttatccccaa ttggagtgac tgatagtttg tgtatattaa aatttgaagt acttgctgag 48181 aagggatatc tgctgaatta cttgaatttt acataaggag aacctcctgc atgaggaagc 48241 ataattatat caacttatga atcaaatgaa cattttatag accagaggaa aatagctact 48301 gatttaatta atggtacttc tgttcttcag gttaataaat tcgttacgcc tttctacttt 48361 tattagagga gttactttgt ttctttagta aacatttatt gtgttgtcat gtttacacag 48421 ctctatatca ggtaggtgca ttgagggata gcaaaggagt aaaatgactc agctcttgcc 48481 tgccttgaaa gactttgctc tgtacttggg atatagaaaa gatacattaa atagtgaagg 48541 gaccaaaata agtgtgagac gatgtgctag aaactgtatt taaatatgtg ttgtggggca 48601 gataataatg gtacttcctg tacacaggca ctgagcactt tatttatgtt gtcttcttta 48661 attcttacaa ttctgaaata gttactctag ttagttgtaa tttgtaagtg ataaacctga 48721 ggcttaaagg ttaaatcatt tgcccaaaga cacacatcta caaagtgacg gaagttagga 48781 tttaaacctt aggttggcct gagtctaatg atcatgatag atagaagtga aggttgcata 48841 cagctgtgtc tttgcttgtt tgcatgtgtg ttttcaaata tgctagatat cttgtatttg 48901 ctcccctgaa tttcttttcc atcctgctct gtaccctggg ttggctgacc tgtgtggatt

48961 acaccagtga acactcttgc cctttggttc tagccaggtt tgaccaatgt gaagaactca 49021 ggagatctga gggtagactg agaatgatgt tgggtgtata taattttggc tgtaccagct 49081 cctgcctcta agtacccctt gattaggtgt acttatacac tgtacacctc ccactccccc 49141 agccccactt aggcttctag agccaatccc, tcctttgagc acccagattc tggtaactcc 49201 acaacccccc tctgtttctt cagctctaag gctagtagtt gcttctaata gttactaata 49261 ttggaattac ctctgtgacc cgttttaatt tttttcagtc tattaacagc tatataatca 49321 gatttattat tcccctagct cttctccatt agattcgcac ctgttggctc catctctctg 49381 tgtctccttc tatcctttcc catttttcct cctttctctg gatcctagga accactcctt 49441 gacctttcca gcaccgagag gggtaaccat tccttgtcat gaacactaac cctgatcatg 49501 actttaaaag ttgtcccttg atcaaactcc atttgaatgc atcatgccca atttgagtgt 49561 tttatggatt tcctgctgag gcagattggt atgcagaaat tcttttattt atttatttat 49621 ttttattata ctttaagttc tagggtacat gtgcacaatg tgcaggtttg ttacatatgt 49681 atacatgtgc catgttggtg tgctgcaccc attaactcgt catttacatt aggtatatct 49741 cctaatgcta tccctccttc tccccccacc tgatgacagg ccccagtgtg tgatgttccc 49801 caccctgtgt ccaagtgttc tcattgttca attcccacct atgagtgaga acaggtggtg 49861 tttggttttc tgtccttgcg atagtttgct gagaatgatg gtttcacact tcatccatgt 49921 ccctacaaag gacatgaact catcattttt tatggctgca taggattcta tggtgtgtat 49981 gtgccacatt ttcttaattc agtctgtcat tgttggacat ttgggttggt tccaagtctt 50041 tgctgttgtg aatagttggt atgcagaaat tcttgtaagg catgccttcc tttcttcttc 50101 cctttcccac tcctgtcctt tcttagtatg ttcaaccttg aggataagaa atagctaaag 50161 catggtccct accctgagga atttataata aaggttaaca tttaattaat aataatggaa 50221 atgaaaacta gtaatgtact tgagaagcag agtgacagag agagaatcta gcaaatgaaa 50281 ttagctgatt actcagtgga aaatgcagac aacaattcac aaatcagttg ctaattcttt 50341 ctaccatgta tattaacttt gtcccttggc cagaattttg aagttatttt ctttatttag 50401 cttaatgaaa caacatcaag gagagtgtaa agtctttttc aatgtaaagt gactgaaact 50461 ttgcttttta gaactcatca tttcactaaa aaataagttc accgtaagaa ctctccatca 50521 gatagaattc ctgatggatg ttccaggatt taagatgcat acaaagtttg ggaaggcctg 50581 tcagtttttt aaaaaaatta ataggctttt tttgggtggg agggggctca actttcagtt 50641 tacaggaaaa ttgaacagaa agtacagagt tcccatgtta cttctcattc cctattccag 50701 tttcccctgt tattaatatt ttgcgtgaat atggtacatt tagtataatt catgaaccaa 50761 gattgactca ctattattaa ctaaagttca tagtttacat tagggttcac tctgtgttgt 50821 gccgttctct gggttttgac aaatgaatga catgtattta ccattactgt atcacacagt 50881 atagtttcag taccctaaaa aattccctgt gcttcacctg ttattcattt ctccttctct 50941 gccctgagct cctgccaacc actgatcctt ttactgtctc catagttttg ccttttccag 51001 atgttatatg gttgaagtca aatagtctgt agccttttca aactggcttc tttcacttag 51061 cagtatacac ttaaggttcc tctatgtctt tccatggctt gacagctcat ttcattttat 51121 cactgagtgg tattccattg tatggatgta ccatagtttg tttctccatt tacccattga 51181 tgtaacatag tttgtttttc catttaccta tcttgattgt ttccaagttt tggcaattat 51241 gaataaagct tctgtaagta tgtagtgcag gattgtgttt ggatgtaaat tttgtactgg 51301 tgtcccagga tttaagatgc atgtgaagtt cgagatggtc tatcggttta aaaaaaaaac 51361 agcctggaaa aatgtgattt ctgaaaaggg gtttatttaa actagtcaca gttaagggca 51421 gatactgact tccttgccag acatacttag gcttgattaa tcacttaatc acatacttaa 51481 gtatgatctg agaattagag ttgaaataca aactgaatat ctgacataaa tcaagtataa 51541 aattgttatc tgttttataa ttgcacatga gcaacgtact caaccacttt tatttcaaat 51601 tgaggaccta aacacattac aaatgcatat ctagagtatg aacacttctt tggttgttaa 51661 catagctctt acttcctttt gagtaagcaa agagccattc tttcaagact tcctgtggcc 51721 accaataatt ctgccgaggg gtctgacatc ttgtgaattt gccaaccttt catcagagac 51781 tttgactcat gctgaaacac ccttcatttc tagtggtctg tttcaatctt ctggttcagt 51841 gttgagccag aacatataaa ttcccatctg aaaacctaac ttcaggaaaa tcacttgaac 51901 ttttttgtgt ctcaccaagt atgaggcctg tctctgcagc ctggggatgt tataaaggtg 51961 gattagccca tgtttttaaa gcacttacag ctcccatggg gaaacctttt gcgacttcca 52021 ggcataatta cctgtgtatt ccagctggaa taaggcaaac agagtgcact cactttaaag 52081 ccaaatgctc atccttttct tttagggact ccatttggct tcctcatatg gggtatatta 52141 atatcttgaa cgtgaaagca tttgagttac aatggggaat gtttcactta ttattcaaca 52201 tttcatcata aatttggact cattattatt ttgatacctg aaactaaata cgtcatgcat 52261 ggtagcccag aatcttcctt aacctaaatt agagtggact ggtgcttctc cttttttctt 52321 tctttctttt tttttttttt gagacagaat cttgctctgt cacccaggct ggagtgcagt 52381 ggagcagtct tggctcactg caacctttgc ctcacaggtt caagcgattc ttctgcctca 52441 gcctcctgag tagctgggac tacaggcacg tgccaccatg cccggctaat ttttttattt 52501 ttagtagaga tggagtttca ccatattggc caggctggtc ttgaacttct gaccttgtga 52561 tctgcctgcc tcggcctccc aaagtgctag gattacaggc gtgagccacc gcgccccgcc 52621 ttctcctttt ttctgaagac tgtctagagc ttcttgatct ggttgtgccc acttaatgga 52681 agcattccag tctgcattat tctccatgta gttagagcat cttgtgtgac aataaacatg 52741 agaaacaact ttatagtttt tttgcaatta tttataaaga tcataaacat gaagtttttt 52801 tagtaactga aaaacaggca caactaacaa tagtggaaaa acacagtctg tttcatagaa 52861 aatgacttag gctaaaatat gacacatctc actgcctttt gagatttatg cctctctctg 52921 ctgacaccaa caagatcgtg tgaactggaa atacttgcag agaaatattt aaaaatattt 52981 tctaaaaaat ataatttata gatgaaaaat tgatgtcaca aacatttggt tgattagaaa 53041 ttcctgtttc tcatttatgt aactccttct ccctttcatt tttcaatagt aagagactat 53101 catagtttta cattttggag gtgcaaatgg tttggactat tcaatagccc aaatggtcaa 53161 atggttttgg gctattgaat agcccaaatc attcactgtg ataaggactt tgaatacagt 53221 ttgatttatt tttgtttcct tgcttgaaat atattttaca aatattttca gtggacattc 53281 atcaacttag ttcattctcc atcttttctt tgccttgaca gagctctcaa tagttgatgc 53341 taaatttatt aaagtagatg taaaaatcta aagctggatg taaaatttag catgtgatag 53401 taaattttaa tatctttagt tttctggcat agtgttggca gagatgttct agatctatat 53461 aaattaatct tttgatattt ttctagatcc atgctgttga atgtggtagg cactagacac 53521 ttaggatttt taagcatgtg aaatgtggct catgggtctg agggactgaa tttttaattt 53581 taatgaattc agataaccac atatgggcca gtggctactc tattggacag cacagctcaa 53641 gtgagtcatt tggttgccaa aggcttaaac tttatcttaa tgacctggcc aacttaacaa 53701 cgacagcaaa aataaaaatt taatggccat ctgtttactt catgctaggg atatcacaga 53761 atatttaatt tttactatat gcaacaaccc tataagctcc tattttacca tgaggagacc 53821 aaggcccagt gagcctaggt aacttcatga aggtcataga gctagtccac atctttgctc 53881 cttctgtttt gccataagat ctaatttttg ttcaaactgt aggatcaatt attatgttga 53941 atggctctca atttagattt gtctgacttt ttttataatt aggttgaggt ttcccaatat 54001 tttcatcacc ctaaaatgaa accctgtgcc tgctagcagt cactgctcct cccacaaccc 54061 ctggcaacca cttacctact gtctgtctct aaagatttct ctattccaga gatttcacct 54121 aaatggaatc acgcaccatc ttagtctatt tgggctagtg taacaaaata tcttagactg 54181 ggtgacttat aaacaacaga aatgtatttc tcatagtcct ggaggctgaa agttcaagat 54241 caggatgcca gcatggttct ggtgagggcc ctcttctagg ttgcacactt atgaagtctt 54301 actgtatact cagatggtag aagggatact ctgatctttt cagcccttta taagggcact 54361 tatctcattc ataagggctc caccctcgtg atctaattac ctccccaggg cccgcctcgt 54421 aataccatca tattggggat tagattacaa catacggatt ttggagcgag gagcataaat 54481 gttcagatct tagcatccac tgtatggtct tttgtcactg tgttctttca tttaacatgt 54541 tttcaaggta catccttgtt gtagcgtgta tcagtgcttt ctttttatgg tttactaata 54601 ttccatcata tggataggac acattttgtt tattcatttg gttgctggag atatgggttg 54661 ttatcatttt tttgttatgg tgaatagtgc tgctataaac acccatacat aggttttttt 54721 atggagaaat aaggtttcat tttgtttggg tatataccta agagtgtaat tgatgtgtca 54781 tatggtaact atgatatgtt tagcatttct gaatcggggg tagtttcttt ttgataaatg 54841 cgattggttc ttcattcctt ctggtagttt ctgtctagta gtgaattaga gttacaatgg 54901 agtatagatt caggatgata ataattaaag aacaatagtg tgtctggtac tctccctaaa 54961 ttctgggtta aacatttaaa aaatgactaa tacttgtttt tggattttgg ggcatagtgt 55021 taaaaacatt ggggattaaa agaatgcatg acagtctttc ctcttatgtc tttcttctta 55081 catttgttct aaaaacctat acgttggttg gtcattatat ataaagtggc attcccagtg 55141 taatctagac aatgggaatc cacagactgt tggtagaata ttggttgaaa taacagtctg 55201 cactttgagt aagtgttaaa gatatcaggg ggaaaattca cgaacccaaa gcaagacaat 55261 aatccctgta agtttatagc attttcgcag gcctcatatt atgttcagac cccaaagggt 55321 tagattatat gcttcctgct gatttgtctg caagaaacag cagaatttta aggtagtaca 55381 gcttcttttt gttcaataaa tatacgtttc ttgctgaaat gacagaaatt tgaaactact 55441 tttaaaaaat atacatagtt taataattcc atgaatgttg ccaggaatga tcttattaaa 55501 aatagggata tgatgaattt ggcccgcaag aatattaccc tgaaacagta cctttggtta 55561 aaaaagaaaa agcaattctg gtataaaaat gtccattctt ttgatattct cctgatttcc 55621 cctgttttgt caagcttata caaataatga tataaggtag aaatgaagga aagtgtccaa 55681 gaatggtaca aagggcggtg ggaaagttcc aagtaattca gaaagagctc agcagtctgg 55741 ggtttttgga ggggatggaa tcctggagcc agggaatgct tctctctctc tctctctctc 55801 tctctctctc tctctctctg tgtgtgtgtg tgtgtgtgtg tgtgcacgca cgtgctcatg 55861 ggtgcagatt ttttggattg actccaacag taaaagcacg accttattaa tttggactcc 55921 actaattaga aaattactgt gaaatggata aggattgagc ttaaagttaa atagcatttt 55981 ctgagaaatt aatggcatag atataaagta aatgtttgac ctattttgga gaagataatg 56041 gtttacagtg cttctgtaat gaaggatcca tgcataatca ttttagtaac agttattgaa 56101 cgtgtagaat gttgagaaag agtagtgtga tggctaagag catagattgg agcatcacac 56161 cccctggggt caaatattgg ctctaccatt tactaattct acaatttgct aaatcaaata 56221 ctggctaact caaatatcta tttactaact caagtatcta tttactaact caaatattgg 56281 ctctaccatt tactaacctg ggcaagttac ttaatttctc tcagccccag tttcttcctc 56341 tgtaagatgg gaataataat attgcctacc tcttagcttt gctgtagaga ttgaatgtat 56401 taatataaaa atgcttagct ctatactcgg tacctgataa atgtaacatt aagtggtaac 56461 tattattact gtgttcctgg caccctgcta agtgcagtga gaagataaaa gagaatttct 56521 ggtgtcaaaa tgtgacgaac taacagataa aataatgtgt attgatatat acatacaata 56581 tcagtgtcat acagtacaaa taggtacata ttttctgtgt agtttactgt ttataaactg 56641 tattcaattc aatgatcttt cagaaactta gtttgaatct cttcaaatgg tggaaaaata 56701 agcattttct ataacatgct ctgtagctct gacttttcct taagttccga atgactttct 56761 cctggttgga ttggtttagt gaagtgtgac tatttggccc tcccatggaa atgcatacac 56821 tgaccacatg tctcaggtga atggacccat caggagggaa tggtcttgtt tcttgaatac 56881 ctttttgtgg cccaactgca aagcagtggc tcctgagtca caggaggtag aaactgacaa 56941 aaccatggag tgcagccact gtgtgaattg ccttcaacca tgactgcttg gcttttagag 57001 atggaacaga cattcgtcat atggttattc cccagtgatt ctgaaaactt ttctgccaaa 57061 atgttaaggc actggtgaat tgagttctat gtctgctgca agagtcctgt ggaaattctt 57121 gagagtctga aatttgccta atgctttttc tcaaactgaa attaaaagcc aaaacaaaac 57181 atcttttgca aaatatctat tgctgccctt ttttctagct tcatttctat tttagaagtg 57241 tgttgagcag ggccactgta gtgtacaact ctgagggaca ctattcatag acagcttacg 57301 taaattgcac cctctggaat tttgagtacg tgatctacat agccacacat ggaggtcctt 57361 gtgccgaatt gtttgttagt tatgttcata gaacctgttg ttacaagttc tttggaatat 57421 atgctagtct tagtgatgaa attgggcagt gactgggtat ggtctttaag tctacatatt 57481 tagataaccc tgtatttaac cacatgcctt ctgtgtctgg tggcattaac ccaaattctc 57541 agtgttatca tcaagattat tatgacatgc cttgtcactg taggtcatct ggtgactagt 57601 ttttaacggg tttctaatcc ttgtgtgctg ggacctcact aagcattctt cacttttgag 57661 cctggcttgt gttattacag ccactgttgc taggactgat tcttctgttg tcacttgaag 57721 gtctaggagg ttataaatgt attgaggctt gtgtgcaaaa gttgctctat ctcatacagc 57781 aaggctggct caattcatac ggtgccctac ccatgtagca agggtctctg gagcaaatgt 57841 aacagctgcc tagtggtagt caaagaactc cctgcattac aaaaggatta aatatgctgc 57901 ttgctagagc ttgtctggca ggagcttcag agtccttcca gggagtaaaa acaattatat 57961 ttcaacaaag gagtaagaaa aattggcacg tccctccatg aggtcacttc actttggaaa 58021 aagcatttgt gtgctttatt ttaaacaact ttgtcaatac tttgaggaac actttcacat 58081 gtttggaact taggagaatt ggtatacaac aagtccatca gtttaaacca caggcattta 58141 gaactgaaag aaattctggt atcatttatc atgagctcct cattttacag gtgacagagt 58201 ctaaggccct gagaagctaa gtaacttgtg ggaagtcaca gagcccatgg gtgataagaa 58261 gtgaaccagc acccaggtta tgctgtgcca gtgaaataca agtcctgctt tgctctcttg 58321 ctctcttgat tttctcccct gaggaaagtg cccttggcaa agccagagat ggggacattt 58381 aaatggggac atttaaagaa tctgttgcct ttggggtgat tttcatttga atacttcatt 58441 ggcatgatag tggaataatg cttatggaat aattcctctg ttaagaggaa taaccttggg 58501 cagttagtta acctctctgt gcttcacttt cctcctttgt aaaatcacat ttacttcctc 58561 acagaaatgc aaggatgcta tgagttcaca cttgtaaagt acttgtaaca gtgcttggca 58621 cagggaaggt gctatgcacc atgagctgtt aggattatga gctggaagtt gccttttaat 58681 tttttatagc tcatttataa gagaggaaat atttgtagaa aggtttcatc atcttgcttg 58741 tattgctttt tctcaagaag aactcaagta tgacaagagc agagactttg gtaccagata 58801 aacatgggtt tgaatctggg ctcctccact ttctagctat gcaacctgat cacctcatgc 58861 ccctgttcag tttactcatc tgtaaagtgg agatgtgagc atgtacttta ctgtgaaggc 58921 taggggaaat ggatgtgaaa cctagctgta gcacacaagt attttttgtt gttgttgttc 58981 cctttgcgtt gagtggaatg tctacacaca ctttggggtg attggaacta agatgggaac 59041 acacacacac acacacacac acacacacac acacacgtag agttctgtta cctccatgta 59101 ggccaccccc ttctttctta ccaactttgg gaaatctctc tccatataaa aaattacact 59161 tcacttcatg tgtattgctt tgaactattt aaaattgttt attacatatt cacactctct 59221 ctcagaaatt gagtggttgg gaaaacgtta agatttattt atcttggatc accctgtctt 59281 tcatacggag ggtgtcgtag atacttagta aggaactgct gatgttaatg gatgagtctt 59341 agcacagtga gcagggagag tggggctcct gccagtatgt tcacaacctg cattctccag 59401 ttcttcccct ccttcagtgt gttagtttat gcctttgagc tctgaggaga aaccattgtt 59461 ttcttgtctc catttttcta gtgtgagaaa ctagaaatat tcccatgcac tgaattgtta 59521 ctagcaaaat ttctgcttca atattttggt catactcttc tatttagtgt ctctctcaaa 59581 attcattgca accttcagtc acctttggtt ttaataaaac aaaaacagat ttttcttcct 59641 tttaatggtt caagagctcc tcgataatgt ttgcatttta atagtacctt tactttggaa 59701 aataggaatt gctttgcaaa aaatactgag ttttcagtga aaattaatta cactataaat 59761 ctgaaagtaa tattttctaa tacattttct gtaactaaat tttacacttt tcacatattt 59821 tatattttcc ttaaaaactt tccaaattgt tgtttttttt tctgagtgtt gcttaaaaat 59881 catgtttttg caattaaact aaagagcttc tgcacagcaa aagaaactac catcagagtg 59941 aacaggcaac ctacagaatg ggagaaaatt tttgcaacct actcatctga caaagggcta 60001 atatccagaa tctgcaaaga actcaaacaa atttacagga aaaaaacaac cccatcaaaa 60061 agtgggcaaa ggatatgaac agacacttct caaaagagga catttatgca gccaaaaaac 60121 acatgaaaaa atgctcatca tcactgacca tcagagaaat gcaaatcaaa accacaatga 60181 gattccatct cacaccagtt agaaaggcaa tcattaaaaa gtcaggaaac aacaggtgct 60241 ggagaggatg tggagaaata ggaacacttt tacactgttg gtgggactgt aaactagttc 60301 aaccattgtg gaagtcggtg tggcgattcc tcagggatct agaactagaa ataccatttg 60361 acccagccat cccattactg ggtatatacc caaaggatta taaatcatgc tgccataaag 60421 acacatgggc acgtatgttt atagcggcac tattcacaat agcaaagact tggaaccaac 60481 ctaaatgtcc aacaatgata gactggatta agaaaatatg gcacatatac accatggaat 60541 actatgcagc cataaaaaat gatgagttca tgtcctttgt agggacatgg atgaaactgg 60601 aaaccatcat tctcagcaaa ctatcgcaag gacaaaaaac caaacacggc atgttctcac 60661 tcataggtgg taatcgaaca atgagaacac atggacacag gaaggggaac atcacactct 60721 ggggactgtt gtggggtggg gggaaggggg agggatagca ttaggagata tacctaatgc 60781 taaatgacga gttaattggt gcagcacacc aacatggcac gtgtatacat atgtaacaaa 60841 cctgcagatt gtgcacatgt actgtaaaac ttaaagtata ataataataa aatttaaaaa 60901 gaaatcatgt ttttgctaat agtatttaaa aagcactcat tcggccaggc aaggtggctc 60961 acacctgtaa tctcagcact ttgggaggct gaggcgggtg aatgactggg tcaggagttc 61021 gagaccagcc tggccaacat ggtgaaatcc agtctctact aaaaataaat ttaaaaaatt 61081 agctgggcat agtggcgggc gcctgtagtc ccagctactc gggaggctga ggcaggagaa 61141 ttgcttgaac ccaggaggcg aaggttgcag tgagctgaga ttgtgccact gtactccagc 61201 ccggcaacag agtgagacac tgtctcataa ataaataaat aaataaataa taaaaacata 61261 aaaaataaaa agcactcatt cattctttag ttattttgcc ctctatggca ggtactgtgc 61321 tggtttctgt gaatatagtg gtgaatgata aacagttgtt ttttgccctt gaggagttta 61381 gcagaaagca ggaaaatatg caatggatag caaacaaacc aattaaaaag caaatcccca 61441 gtaaggctgt gagggtacag tttttaacct cagtttcagt ccgggttatt aattgaaagt 61501 gcaataggag aaatgatgat agagtagctt ttaagtaatg aggggaagtt ctttcaggtg 61561 gtagcagatc cctgaagtct tctctccttt ctagaaattc aggcatcagg gaaaaagaag 61621 attttggaaa ggaattttct agtgtatgta atacaggaga actacacatt taaaaatttc 61681 tgcatttgca gcccctaata gcaatagtta gaggagtagt agtattccat aagtgaatta 61741 taccttggct gaagtttgag taattacaaa tgtagactgg gaagttgctt catttagcaa 61801 atcagttctg atatagacac aggacttatc tcgataaaat catcatgctt caggatggat 61861 gtacacctat tttgggacac caaaaggaac tataggtgtg accatagcac tctgtttagt 61921 ccttcagtgg ccttttccac tgctctcaca tccaactcag tagcccagca gagttccctg 61981 cctagtccct gccttcccct gcagcctcat cttctgccag cccttgtcct ctgatgtact 62041 tccattgccc agtaataggt ggttactctt ggtttccaag tgcttcatgg gaccttttgt 62101 gtttgcatcc ctgtacctgc tattcttatt gccttgaata caacgttgct tggttaactt 62161 cttgttttgt ttccaggccc agctcagata tcttttctta agcaaaaact ttaagacagt 62221 atttcataaa ctctggatca gggttaatgt taaaaaatat acaaaaattt tatttttatc 62281 aggctgtgga agtgattctg attctctgcc agggttgtga cgctgcagct ttccatgaag 62341 tacttcacaa gtaggtatgc tgtagaaata agtggattca caccagtttc ccgaatgaga 62401 catactatag ccctttttgg atgacttgtt gcacatgtgg gcatattaac agctttgaga 62461 attagtgtag caaatacttt aactttgatg cagtacttct caaatttatt tgaccgtgta 62521 acactttggt ttgaagatat ctgtcaatat cttgagaaat gtctgttatt tcacggaaca 62581 tagtttggga aaatgttgcc ttaaaacatg gttttggtta agaagaggcg gtatcttagg 62641 aaggaaggtc ctgaaagtaa tggaaacacc aggcaggttt tgttcctctt tgaatggatt 62701 ccatgacatc gtttcagtat ttcaatattt acttcatttt cagtggagag tcattaaagc

62761 cattgctgtc ctgattgcca catagtccaa acacaagaaa tgcacatttt gtatcgcaat

62821 ctctttcaat aattttttat ttgaaaattt tcaaacacat gcaaatgtag agagaagagg

62881 acaatgaatc tgcatatgcc tattacccag attcaaccct tagcaaggtt ttgccatatt

62941 ctttatcatc taactttttc ttgctgaact attttatttt tatttattta tttacttatt

63001 gattgatata tgatagttgc acataatagg tataaataat tttggggtac atgtgatgct

63061 gaactgtttt aaagcatagc caagaaatca tgtcatttca ctcttatagt catcattgta

63121 catctttata aaaggggaca ttgcctggta tgacctcaat agtatttttg cacctaccaa

63181 attatagcaa ttccttggct aatacccagc ccgtattcga gttaaaaaat tgagatagaa

63241 ataatatacc atgaaattta ttcttttaat gcacaattgg gcttttagtg tattcacaaa

63301 gttgtacagc catcaccact aattccagaa catttttatt atcctaaaag gtacctgtac

63361 tcattagcag tcactcccca tttttttctc cctccactaa catagtttct gcatttggat

63421 tttgcctctt ctggacacta tgtggttttt ctttactggc ctctttcatt tagtttaatg

63481 ttttcaaagt tcatccatgt tgtagcatgt atccgtactt tttttttttt ttgagacgga

63541 gtcttgctgt cacccaggct ggagtacagt ggcgcggtct ctgctcactg caagctctgc

63601 ctcctgggtt cacaccattc tcctgcctca acctcctgag tagctgggac tataggcgcc

63661 tgccaccacg cccggctaat tttttgtatt tttattggag acggggtttc accgtgttag

63721 ccatgatggt ctcaatctcc tgactttgtg atccgcccgc ctctgcctcc caaagtgctg

63781 ggattacagg cgtgagccac cgtgcccagc cagtactttc tttttatagc tttatattcc

63841 gtggtaggga tagatcacat tttgtttatc catccattag ttgacggaca tttgggttgt

63901 ttccactttt tggctattat gaataatatt gttaggaaat tcatatacaa gttttcatgt

63961 tgatgtatgt tttaattttt cttagtgggt ttgctaggtc gtatagtaac tatacgtata

64021 actttttgcg gaactgcaca atcattttcc aaagtgattg caacatgtta tatttctacc

64081 agcaacttac aaggtttcca atttctccat atccttacca atacctgttg tctgtttgat

64141 tttggccatc tcagtggatg tgaagtgaca tgtctttgtg atttttattt gtgtttccct

64201 actgactaat gatgttaagc actttttcat tggggtatta gctatttgca tatcttcttt

64261 ggagaaatgt ctgttcaaat cctagcctag tttttaagta ggttatttgt ctttttacta

64321 ctgagttgtg aaaattcttt atagattctg gttgttagtc ccatatcaga taaatgagtt

64381 gcaagtattt ctctttgggt tgtcttttca ttttcttaat gttatacttt gaagtacaaa

64441 agtgttaaat tttgattatg tccaatttgt ctattttttc ttttgtttgt atttttcgtg

64501 tctaatctaa attgttgtct aatctgagat cagatagatt tatctcttta ttttcttctg

64561 agagttttat agttttaggt cttacattta ggtctttatt tgagttaatt tttttatatg

64621 gtgtaaggaa ggactcgcat tctttttttt tttttttttt tttttttttc aactggggcc

64681 ttgttctgtt gcccagactg gagtgcaatg gtgtgatcat ggcttactgc agccttggtc

64741 ttctgggccc aagcaatctt catgcctcag cctcctgagt agctaggacc acagatgcgt

64801 gccaccgtgc ctggctattt tttttttgtt tatttatttt tttttacaat ttttattaga

64861 gacggggtct cactgtgttg ctcacactgg actcaaatga tccctgctgc ttggcctccc

64921 atgcttagga ttacaggcat gagccagtgt gcctggcctc acacacttaa aagtagaatt

64981 ttagcttcag ttttcagggt gatctagaaa tattgctgtt ttctctttgc ctgcatccac

65041 ttgtgtacct catctgccat cccatctcct cctcctccat tcttaactaa ccatgacata

65101 atttattaga atctgtttgc gtagtaggta gtagtgcaat cagagtctat gaaaggacaa

65161 agtctctatt accaacataa ttacattcaa ttaagcaaac aaccaagttg taatggatat

65221 ctgctgtttc tgccttctgt gccccctcta tttttctgga cgtgggactt ggtttgctct

65281 ttgtgaaact ccctacccac agtttagtct acagactgac cttgctcaag gagtgggcaa

65341 attgcagtga tttggccaat gaggattgtg tctctggagc tacagtggtt gtttcagaga

65401 tgtacacaga cccaaaaagg gtcatgagag agatacctat aattagtgag aaagaaaact

65461 gctgtagcct ggaatattgc tgccttacca ccagaaagtg gtgtctattt atagaaccaa

65521 catgaagaaa cgtgagccaa gagatggaga gagacagatt cttaactatc aattaaacag

65581 ctggatctag ctgtgcctga agcttagact atttctggac cttttagata catgagcctg

65641 tacattcctt tttaggtttg cagctgaaat agttgtgact gttatacaga tctagtggtt

65701 ggaactgaga acacaagata taagaagata ttttctgctt ttgtggactt gacaacctaa

65761 aagtgagaca gacagacatg agtaaatgaa taaatgacaa atgcaagaat tgatatagaa

65821 tagattgaca gcacagaggc aggagtgggt aactattgag gagggtttaa ggaactggaa

65881 aaagtcctca aaaaatataa attctgattt ggggttggaa gataaatttg catttacttt

65941 gtttttctgt aaacaacaaa actgattttt ccacagtagc ctgtgggagt tattttcact

66001 attttatagt agttggatgt gttgttacac tctaccattg gtatgactat accatggcac

66061 ttttctacta gttatgcaga ggctgtagga agtaggtata gcaggttata taatttggga

66121 agtggcatta agttttttta gaaccttatt ttattcagtg tattttcgaa tgagtttcca

66181 gtatggtatt ttgctttaag ttgacttaac tctgtagact tgggatcatt tagttcaact

66241 aatttatttc atggagaagg tattgtagcc tagataggct aaagaatatg cccaaagtca

66301 cataggactg aaactataat cttgatttct ttatccttag tggagtcttt ctacaatttc

66361 ataccttctg tttgaggctt tgtgttagac tattcttgca ttgctataaa ggaatacatg

66421 agactgagtc atttataaag aaaagaggtt taattggctc acgattttgc aggctgtatg

66481 agcatgatgc cagcatctcc ttggcttctg gggaggcctc agggaacttt tattcatggc

66541 agaaggcaaa gtgggagcag gagcagacac atcacttggc aagagcagga gcaagagaga

66601 gtgatgggag gtgttgcacc cttaaacaac cagatcctgt gagaactcac tgtcatgagg 66661 acagcaccaa aacataagga atccaccccg cgacccaaag acctcctccc acaggcccag 66721 cccccaacac tgagtcttac atttcaacat gaaattcggg tgggacagat atccaaatca 66781 tatcattcta cccttgccct ccccaaatct catatccttc tcacatctca aaatacagtc 66841 atcccttctt aatagtcccc caaagtctta actcattcca gcattaactt tcttaagaac 66901 aaaagctggt gggctttaca gtaaaattgc tgaggaaaaa aaataaagaa taggggaggt 66961 ttttatgtgg atgagctctc tgtttagcaa gttgccagct ggatgtcttc atcattgtaa 67021 gtttggtgcc ccggctctcc tggaatggct agttagatgg ctcccgtttc ccacccagat 67081 ggtgctctct gtgtctgttc agtcaggtag gaagttgtga tgatcgtgca gattgtcagc 67141 atacctattt ccagcgttca ggatttccac catactgaat ttgagatcaa gtaatcctta 67201 gaagccatag attcttcctc tcaggagatg actttttttt ttttcttttt tcgggtcttc 67261 attactgagc caccatctcc cttctgcaac cttgataaga aggttattta ggttcactgt 67321 agcttgaata aggttatcag aagcaattca gaaaatgtta agatgtaaac aaatgaaaga 67381 aaaaaacaaa actaaagaaa gaattttttt tccctaaggc aaaccaatgt taggtccttt 67441 gcagtggcac tcaaaatctt tatataggac agcacagaag ggaaatctgt gtggcagtcg 67501 agatggcttg tcttgatgtt tcattttgat agcaagctcg tatattttta tcttgtatgt 67561 tacttggggt ggctcaatag ggggcatttg atggcattgt gggagaaagg gtaatgccct 67621 ccactttagc ttatatatca ccactaggca tttcttcatc tctctcctga tgctcaatgg 67681 aattgtttct aatgaatttt atgactgttg tggttatgaa acttgcataa caaacaagca 67741 gttccttcag catatgtaaa aacagaaact aaatcaatat ggtataagct cactaaaagt 67801 ttgctgttta aaactgagga tgccttaaaa aagacaatcg tgtttaagcc cagttgcaaa 67861 ttattctgct ccatttggag tctaggaacc atttgccaga acttcaggaa ttgagtttct 67921 ggccagttat cttcgcagta gtgaatgtaa tttatttggg ggatgaatga agcaggaaga 67981 ataacttttg gagttgcctg gagttaatgt ggaaaggtga ctggacagag gtgaaatctg 68041 agtaaagcta agagaggaga atatagaata tgaagatact gtattctttt tcttgggtaa 68101 tacctttatt gatatataat tcatatgccg tctaattcac ccattttaag tatacaattc 68161 agtagttttt agtatattca cagggttgta aaaccattac cacggtttta gaacattttc 68221 atcatttcag aaataatcct tgtgtcctat agctatcacc cacttacgtg ccctccttgc 68281 cttccagctg tgagcaacta ctaatagctt ttctgtgtgg acctttttaa aaaaacacat 68341 ggagtcatac aattacaata tgtgattttc atctctggct tcttttactt agcataatat 68401 ttacaaagtt tattcatggc ctatgcatca gtgcttcttc ttctgttttt tttttttttt 68461 tttttttttt ttttttttta ataatttggt ctcactttct tgcccaggct ggagtgccat 68521 ggtgtgatca tagctcactg cagcctcaaa ctcccgggct caagtgatct tccttcctca 68581 ccgtcctgag tagcttggac tacaggtgta caccacaaca tctggctaat tttttatttt 68641 tagttttgta gagatggggt ctcactatgt tcaccaggtt ggccttgaac tcctgggtca 68701 tccacccacc tcagcctcct aaagtgctgg gattacaggc ctgagccacc tcgcctgggt 68761 catatttttt aaatacattt atctagttga tgggcatttg ggttgttttt acctttcggc 68821 tattatgact aatgtagcta taaacatttg tgtatatgtt ttactattac agaggaatag 68881 gtcagtgggg aaattattct aagatactgg acacatttta ggttgccata atttaaatgc 68941 tggttgattt tttttttctt ttaacataga acagtaaatt tactagtaag gagtggagaa 69001 aaaatgattt cacttcagtt tgtggagctg gaaattttca actggttcca ttctaaggaa 69061 ttattaaatt agtttcctca tacacagttc tcacattctt aatagctttc catgcctaag 69121 ggataggact tctcccatca agctgtaggg ctctatggca gtgtttctta agggtcaggg 69181 aggagcagta gtagaggaaa caaacatatg gatatacttc agtgtgttag gtgccgttat 69241 aagggtacca aagattgggg aaagaagagg gagtgatgct ttcatcctgg aagggtcagg 69301 aaaggcatca cttcacagat gtggccacat tcaaaactga atgggaacct gcattccctc 69361 cctccctccc tccctctgtt gcccaggctg gagtgctgtg gcacaatcac agcccacccg 69421 gtggcacagt cacggctcac tgcagcctca accccttggg ctcaagcagt cctcccacct 69481 cagcttaaaa ttggttaagt ctattaagca atttaaaatt ggttaagtct attgctcaga 69541 gacacaatag atggtgcttg ttaacagtat tttttctagg agtcttttga cttcagtatg 69601 ataaatattc caacacacat cattacccta agaaaagttt ataagtgaat aatcacaaac 69661 ctatggtttt gtaaatcaca aaagtataat ttcatgcctt atttgttgtg caacatatcc 69721 ttactttgct ttcatagtta ctgctgattg taccattaag ataatggagt actgcaactg 69781 atgcattttt aagtattctc acctccactg acttgtatca aggttaaaac ttatttttca 69841 tagatatcaa ggacctaata agctgagtta acaacttgtt tatcactcca tatgtacaca 69901 ccacttacag cttttgtgga gtgttcagtt gtgctgattg cattgggatg aatgtattat 69961 tatggaaaca ctatttgacg tttgggagct taactaagtt gtcttggaga ctctagttct 70021 atagtgagat agtctattgt tcataatgaa ggggacatca aattgcacag aaattctgaa 70081 tgagtcttaa tgagagggct acttttaagg ataaaacact atttttaaga atatgattat 70141 ctatagcgag aaaaaaaatg cagcctttga agcacagcca tgtattaatt actgggatag 70201 gagtcaacta gagtaggatc attaaggaga atctgtattg ttgaacctct agctggtgga 70261 ggtggctggg ggccagttgc tgggattgtc agagtttaga tgagaagttt cagcttcagt 70321 aaatcttatc agtcttgaga gaggatagcc atagctaaag acaatcagtt agggaaggtg 70381 ggaacacaaa ttcccctaga agagtattaa aagatgaatt tctgcagatg tagatatgtt 70441 cattgtgaga agagaaatga gctatagacg aacctcagtg cttaatttgc ttccatgatt 70501 atatttggaa atgggaatgt agaaacaaaa caaacttaga tttttagatt tagaggttta 70561 gggaggattc ccttttcaga gggctgaaaa ataccataaa atgcataatt atggttgatg 70621 taagcatctt tttccaaaac agtttggtct aggcagttta aaaaatggta actggaaacc

70681 acagtgacac ccttgcctcc ccctgcaaac tggccactcc agacctcctg ggacaggcca

70741 ggacaccacc tcagcacacc cagtctggct cagcctccaa acaggcactt ttctcacctc

70801 tccttccctg cctggacagg agcaccacac cccaaactga aggtggagct cagctctgtc

70861 catctggaat attttgacat atggtgtaga ataagatcta aatagttttt atttccccaa

70921 atcgtcaatt tcagtagccc catttattaa gaatagtttt tttcttatta tgtggtagtt

70981 ggctatagtt aagacagagg gccagtttgt atggctcaac aacctggatc tcattagtgc

71041 tgagatggct tagggttggg aatggttttg aggataagag agcctggaat tttgcccact

71101 caacctttct tttccataca tttaaccttt cctatatagt agggattttt ttttcttcct

71161 ccaggcatta tttttcattt atctgcatgt ctatttttgt gccacagctg ctgttttatt

71221 tgttgtagca atattataac actttcttat aactggtata gtctggcctt tattttgctt

71281 tcaaacttct taaaagtatt ttcatttgtt tgaatgcttt gcttttaagg tctgaatata

71341 ggattttttt ttcctaaatg aatgctgtca tagatcatgt agagcttttt ttcttgaaat

71401 ataaatttgg taattgcaaa gtatcatcaa cagttaactt tggctatttt aaagttgata

71461 ggacggaatg tgctctataa cttttaaata accagccaac tctataagac tttataaaac

71521 tttaaaacac cactttcttg aatctccttt agaaatagaa acaatttaat acatctatgt

71581 attaataatt tgttctcttt tctgtatata tgcaaacaga tatacaaatg ggctgctttc

71641 taaatcagtt aagtattggc ctcctttcca tgatcttaga gtaatatgat tcaaggatag

71701 cagaaacatg caaaactgag agaaaacctt tcatggcaac taaaatcttg cttctgctta

71761 ttgatttgtt tatattttgc ttacttttac aagttatttc agattgctta taaaagtcca

71821 ttttaataag acctaaaaca gtcaaggcag gaaagaagaa aactattata gaagaggagg

71881 ggatggcaaa gagccttcaa ggtggagtta gcaaactaca gttcatcaag aaggcagtcg

71941 ggagaccatc ctaagaataa tcattatgta gattcattca tttgttcagt aaatatttat

72001 tgagcacata ctatatgcct gtaatctctt aagcagtgaa aatgcagtaa tgagcaaatc

72061 agacacaaat ccctgctttc acaatcatag aggttgcatt ttagtggaga cagtaagcaa

72121 aatgtttagt ctaaatagta tgttacatag taatagttgc taaggagaac acattaaagc

72181 aggaaaagga gataggaggt attgagggag gctttacatt cttcatggag ttgtcaggaa

72241 gggcgtccct gagaaactca ctttggaaaa tggccggaag gctgtgaggg agctgtaagg

72301 gtgtcaaggg aagagtgtac ctggcagaag gaatagcaaa tgcaaagacc ctggtgcact

72361 tataggagga agttgctggg gagaggttgg gtggagtgag ggaggagagg gtagtaggag

72421 gtgggtcatg gttggcatct gcaactccag gaccagtctt agatgtttca tttttttttt

72481 tttttttttt tttgagccag ggtctcactc tgtcacccag gctggagtgc agtggcgtga

72541 tctcggctca ctgcagcccc aaccttttgg gttcaagcga tcctcccacc tcagccttgg

72601 gagtagctgg gattataggt ggatactacc acacttggtt agttttgctc gtttttttgg

72661 taaagatggg gtctcactat gttgcccagg ctcatctcag actcctgggc tcaaggggtc

72721 ttcctgcctt ggcctcccaa aatgctggga ttacaggcat gagccactat agccggctca

72781 gtcccagatg tttcaaggct cttcagagaa gaaagagcag ggcaacagct aaagccaaag

72841 aaactagcct tgctgtactt tctacatgtt tattcagttg tatatcaagt tttttttttt

72901 tatgtgtttg gagtttctga tagcttgaag aatgaaggga agtaatgatg tatgcaagtt

72961 taccatgtct gttatattta actttgacat agaccatttt gaaatcttag cagatatttt

73021 aggatgttct tcaaaatttg atacatcact gtttattttg gaagcaaata acaaaagact

73081 tccctggatc gacttgtcat tacaagtgct tagacaaata cccactaaca gagtattata

73141 ctatatagac tggtaagttc catggttcgt agtcttgttt aagcaatcag agtgataaat

73201 cctgaaatac aattttctga cattcaccta cctaccaatt ccctcctaaa tttattggtt

73261 cctgtaaaac ttactgtgaa acttgagcta cttgtaatag tttcatacta attttcactt

73321 tttccaaaca aaggtgcctt aaagttatgc tgccaaagtc ttgtagtaat tttctcactt

73381 tcttattgtg ttgcaggctg ttaatcggct tattttaaga aaatagagag atgtttgtaa

73441 aatcttggtt tcagttgtgt tcttaaaatc taacctgata gtgattttac tgaggcctct

73501 tttgtgtatt cactaaagga agaaaacacc aaatcacttt gccttttgga ggtgatggag

73561 aagaatacat aatatgtttt cctggaagct gttttttttt tccccttgtg aataggagga

73621 ggaaagccta ccagctgtgc ccgatgcatt tataattaag cctctcttct ctgaagttga

73681 tgttttggtg tctaaaatga cttgattttt tccattttag tgacatttac gaatcttatc

73741 cctttgttta atggaaaggg gaaatgggag caagtgttac aattgtcagg tctctgtgat

73801 tgatgcctta gtgccctgct ctagggcatg tcgtttcttt aggctgtcag gaatgggtta

73861 ggatgatgcc cagtggtgcc agctgtgtgg ctgacaggag ctgggccact gagttgcctc

73921 ttcggcagag tcaacatttg ggccagagag actgcgactc agcgatgagt gtaaacattt

73981 gtttagtttg aatgattagg agcagaactg gtcttggtta ttagctgatt gtaagaatca

74041 agtggagcaa agccacagcc tttgttgagg aacagtactg taagaggcat ataacatagg

74101 ggctttaagg gaagcccgct tatgctcaga atttcaaatg aagccacagc gttggaggat

74161 gggcggttgg tgggttctcc aagactaagc agagggaaca gcagaggagg agagagtgga

74221 agtgctttat ctggccccct tggctgatgc ttggggtgaa ggcaaagtgt ttggtcgctg

74281 agacctttcc cagtcacatc agctggcaca tgagagaata aacctgaccc aaagctttag

74341 aggagaagaa acaggaaaaa attaccacct gtattatgat ttgtttgtgt tcgtctcttc

74401 cactagactg tggatgtcct gagggtgatg tctgtgctta ttcattttat atcatcagtg

74461 tttattgaaa tgaactgaaa ggtgtgatga attcctcctt taaatgtgcc attttttagc

74521 ctcttcaggt taagggtaac ttgttattcc ggtatgttgt gagaagcctc ggtgcataac 74581 cttttcattt tttttttaaa atagaggatt taatgaagaa ggattgcaca agagcagagt 74641 gtagggtaat caccatataa actcagaaat cataattggt tcattgttca ttcattcatt 74701 catcagcact agctattatt tgctaggtcc tggggatgca aatcatgaca taaaaagttc 74761 cttaagaagg tgatcacata cttctgtatt tgagataaga agaacaagag aataattatc 74821 caccttaaat cagtagccta caaaggaatc gtatcaggaa gagttgcaaa gagagttgga 74881 aacaattttg ttttgtttta ttttcatttt gagacagggt ctcactctgt tgcctaggct 74941 ggagtgtagt agtgcaaaca agtctcactt cagcctcagt ctcccaggct caagcaatcc 75001 tcccacctca gccccccaag tagctgggac tacaggcaca cgccaccatg cccggctaat 75061 ttttaaacac tttttgtaga gatgaggtct tggtatgttg cccacgctgg tatcaaattc 75121 ctgggctcaa gtaatcctcc tgcatctgcc tctcaaatgc taggattaca gatgttagct 75181 actctaccca gcaggaacag ttcttaaatc tagctcagag ataatattgt gtgattggct 75241 taaactgtat taactgattg caacttgaat taacaaaata atctgagttg catatacaaa 75301 caaatacttt aaagcttatt taagttttta aataatttac ctgaagtatt tctatgtgtg 75361 tttgataata atattaatga cttactagtg taggtaatat actgtctctt taataacctg 75421 taatgaaaat tatccctcac caaataaatg tatattttgt caagttgtct atcatatatt 75481 ccttccaaga acctctagat gcaccagtcc ccaaagcagt ttattttaaa agagacttac 75541 aagtaatagt acagagaaat ggagagccta ctgctataat ttttttaacc tcttaaaata 75601 ttctgcaaat tgtgaatatg ctggaagtgc tcttagtgac tccagtagtt ttattgaatc 75661 aaaagtagtt tactttctta gcaaatcaat caatttttgc tggcatagta cagctatgct 75721 gtatgatttc ttgtataagt cattgaatct gtcattttta agaatgaatt tttaaaaatg 75781 atcttttgct atatagattt atagtcagca taggctattg aagaaactgt ctcagagcat 75841 ggaggatgaa tgtctccaac tcaaaaatgt gttgtggctc tcggagacta ttgtcttcat 75901 tatctttctc ctggtgcttt agatgtaatt aaaaattact atgtgtaatc aagtataagg 75961 cggttataat agtattctgt ttttgtttat atataaatag aatttttgtt tatatatatg 76021 tttagtttat atatattttt cgtttgtatg tatatccctg taaaaccttt atggtagttt 76081 gaggactaaa taagacatgt ctgcagtaag ataggagtgt tttggaggat ctgagtttct 76141 ttatattgtg aaatattagc tcagctaatg atattagaag gacatcagtt tatatctgcc 76201 tcggacttat tgacaacctc tttgagatga atttaaattt ggttgtatca ttagacatag 76261 cttctagtat ctgatttaaa gttactcagt ttagtttaat gttatattgg gtcttcaaat 76321 attatttggt ataattaaat ttttgcattc ataacacaat ttgaatagaa gagcaccagt 76381 ttttcattga ttggagaaat aaaatatagc atgaataata aatttaaagt catgatgtaa 76441 aagaagccag atgagaccct caggtcagat agaatgagtt tctatttgtc ttgctctaaa 76501 agacactgtg ttggaaaaat ctattgggtg aattaatcag attccctctg caggctcttc 76561 ataacttaag gcagtgaata gagttgcatg tctcgttgtc atcacatatc agatatgcat 76621 aatatgtagc gattcagatc agctgcggga gtgtttgggc gcttttgttc ctttgagtct 76681 tttaaagtgg aaaagaagtg gcagtgcata aaagttagct ccagctatta ttattttatt 76741 gacctgtttc ttcctaatgg aaacaacatt gtgatcacaa attagaaaat gaaagaactc 76801 acttttaatg gtttgaaact tgtagggcaa acaagatttt ggccatacgt ggatgtactt 76861 tagaacatgg ctatgtacac attttccaaa aactctgttg gaaaattaaa gtatttttta 76921 atggattctg taaagagaca gatagtacat tgtggagttt atatgtattt gaaaatatgg 76981 atagtttgat ttattttaca agagtgcatc aaggccagag ttttaattct cctcttatgt 77041 tctgttattc ccttttgatg tgcatatttc tgttttttat gaaatacttt aatttagact 77101 taactacttg gta'cacacgt ttcaaactat tatatatcgc ctggcaccag atgtttttgc 77161 tttcccgtat tgttggtcta ttggaaaaca gggaggctct taactgaggt tgcctgtaaa 77221 cttgatcaaa tgtcacttta atccctgtgt acttttggca aactgagagc tatttaggaa 77281 gtacttagtt cgcttgtttg agacaaatat ttccattaca ggcttggtgg aggtgactcc 77341 atttaggtgt cttctagaca ctgtaactga cctccattta acagactcat gggatgaacg 77401 ggtcctttac attctctctg agaacatact gactggtggt gctcagctgc tctctgggat 77461 gcctgtgcac tcactgctgc ttgcactgtc aagctgaatg tttatgccca ttgtacttgt 77521 gtttgtaata atataacaat taactgataa aatataagtg cataaaaaag aatgtggctg 77581 tttctatgaa aaaataaagt aattgcatta aaaataggat acaggtgtta ctaaactttt 77641 ttattgactc aaatgtagga gagacaactc tatatagact gcatagattt aggagacttc 77701 agccctagtg tctttaaatc ctccccttat gaaacctgat actggaattt gtagatgatg 77761 ctttggttat ggttaatgtg gaaaaaatag ctcaattcct ggaccatctt caaagaaaaa 77821 ttcttcactg catttcaaaa gatacttgag tgaatgtcca tttataagaa ttaagttaac 77881 tgaaaatttt aaggtatatt ttataattta tttttatgat tcaccatttt aagtaacatt 77941 tttgctttgt ccatttacta gtggtatcca ctgcattaat aatggtggag tattatttta 78001 catcctttac ctgtatctgc attaattacc tgtatctgtt tatgcactga gggtgtattt 78061 gagcctcatt actttgttat tttcaattac ctagttacag gtcctgaata ttaaagttta 78121 ccttttcact atctagtaag aacgtatcca gtaaacagta ataacctaga aaaatcttta 78181 agggaaaatg tataaatatc taaaaaaaga cttgacctgt ttgtgtagaa gtaagctaag 78241 tacattttaa aactttttct ttggaaataa tttaaacttg aaaacctgta agaagaatgc 78301 agagaatact aaaatatcct ttaccactag ctttgttatt ttttatcaat caatcatctg 78361 tcggtctatt gtgtgtgtat atagataggt agacatatag tctctttttt gaactatttg 78421 aaagtaagtt gcatataaga tagtatatat ttcttaggga taaagatatc cacttacatt 78481 atgcagtgca gttatcacct tcagtatgtt tatacctatt cagcatatct gaagttatca 78541 acctcagata cgatacttat tatcttttat atggtttgtt ttccaattct gtcagttaac 78601 ccaataccac cttttatggc ttctgttcac ctcagtgcag aaccaagtgt agaatcatgc 78661 attacattta cttgtcatat ctttttagtc tcctttaatt tggcatagtt cttcagcctt 78721 cttctatatt tatgaattga cattttaaaa tataggtctt tttaaaaatg gaatgtccct 78781 catgttatgt ttatgtaatg tttcctcttg tttagtttta ggttatgtgt tcccagtggg 78841 aatgttatgt aactgatatt gtgccctcag ggtttcacat ctggaggcac atggcgtcca 78901 tctgcttctc agttttgatg ctaattttga tcatctagtc aaggtgttag tcgatttctt 78961 tatgctattt tttccccttg ctactgtggg caatctgtgg ggagacattt taattccata 79021 cagatgcctt gctcctcatt aaaatatttc ccctagagtt agcattcatc gatttgtctt 79081 tactgtggtg gttacaaaat gatgacattt ccctccaaat tgacccttgg ccttctcacg 79141 tgcaagatcc cctatatttt ctttctttct ttattcattt atttctggtg tgaacttaca 79201 gattcctgtt ttcctgcaat ggcctataat taattactgt ttttaaagat aattttggtg 79261 ctcagattat ctgaatgggc aaataggaac ctcttcaagt tggctcctat gtcttagtga 79321 tatgcccaac tattttagca ccttcctact ttgtgacata actagatttt acaggctttt 79381 attttatgct tttgtgcttc agcatttccc catggaccct gattcctctg catggggaat 79441 gctattagaa accaaattct gggctgggca cagtggctca cacctgtaat cccagcactt 79501 tgggaggcca aggcgggcgg atcacctgag gtcaggagct tgagaccagc ctggccaaca 79561 tggtgaaacc ccatctctac taaaaataca aaaattagct gggcgtcgtg gcacatgcct 79621 gtaatcctgg ctactcagga ggctgaggca ggaggattgc ttgaatttgg gaggcagagg 79681 ttgcagtgag tcgagattgt gatattgcac tccagcctgg gcgacagagc gagactctgt 79741 ctccaaaaat ccgcaaaaga ccaaattctg ggtagatgtg ttcattggta ctgggaatct 79801 gcttttaggg cctttgagca gatagagcta gaaaatgtac gtgtgtgtgt gtgtgtgtgt 79861 gtgtgtgtgt gtgtgtatgc attcatatat acattcacat gcatgtatgt gtatatatgc 79921 acatgcatgt gcacatacat attttaaaac tgtgtccact tataacctta atttgaatcc 79981 atccctgtag aggtttttta tttctcccat ggtaagaacc ctaacttgca acgacttcaa 80041 tatatttact tgtttgctaa aatctatatt atatctaaag tactttcaga attgttgtgc 80101 tgtagcacta caaaatcaaa cctaataaaa agagtttaga gttatttata gttctcttcc 80161 cattttgacc aagaatgttc tccaatcaag aatactgtgt tcataaactt ccataagttg 80221 ttcttttatt gtatatattt aatgtgtaca acatgaagtt tttataaaca tatagataat 80281 gagaaatgat tactacagta aaaccaggta acatatccat cacttagcag ttaccttctt 80341 cttcatggca gtggggctat attacacatt tgaaatacaa tttggatttg tttgtttact 80401 ttcagtttta ttccttcttc cccatccttg ttgatttaac tttatttttt gaatgtcagt 80461 aacagtaaca tgtttcaaaa agtcaaacta ttcaaaaaga tatactcaga gaagtgtcac 80521 ttcctctagt gtcctgtcca gtctgttctt acctctccac cctccatata ggtaaacaac 80581 ttcaacagtt tcctattgta gcccatacta aaggggaagg gaattaagat ctgccttttg 80641 aagtgaggca tatcaaagaa tttgggtaca tattttaaaa ccatcacacc gtgtttatgg 80701 ttctttaaaa cttacctgtc tgtccgtcca tccatccatc cattcattta tccatctacc 80761 cacccatgta tctactgcac atatatatgt ttccttgttt ttaagagctg attgtattgc 80821 taggggcagt aatctttgcc tttcatatat atatattcat attttcatat atatagtgaa 80881 tatttttcta attttccatc ttttaaatat gtatatgttt ttatgcatag attttttttt 80941 tttcattttt agggaatcat cctattatgg tttctggttt tggggtatgt ttataaaagt 81001 tttcaccatt ctaatatgag aaaaatattt acctatagtt tcatctttta tatttacatg 81061 ctttaattac ctgaaattta ttttagcata aggattgagt aggaaattca tcctctcttt 81121 tctttcacat tgctttctgg ttgtctcagt agcatttatt gaataatcca tcttttcccc 81181 actgcttcaa agtgttgcca ttatcataaa ttattcttaa tatatgcttg ggcctgtatc 81241 tcaatgatga tattatatta tttgtctttt cctgtgtcag taccaccctc ttttatttac 81301 tgaagcatga taatgtgctt atcatacagt tagtcttcca gtaaacatta gaattacttg 81361 tttcaaaatt taaaacattt tctattgaga ttttgattag cctggcattg aatttattta 81421. atttattata tttctttaga gatagagtct tgttctgtca cccaggctgg agtgttagtg 81481 gcactgtcat agcttactgt agcctcaaac tcctggactc aagtgatcct cctgcttcag 81541 cctcccaact agataggact acaagtgcat gccatcttgc ccagccaatt aatttttttt 81601 tttttttttt ttttttttgt agagatgagg tcttgctttg ttgcccagtc tgcccttgaa 81661 ctcctggctt caagtgtgtg agccacagtg cctagccagc attgaattta gaaattagga 81721 agaactgata tgtgtaaaat attcaagtct tactgttcaa atacaagttc tctctccagt 81781 cattttcctt ctgttcctta tttacatttt ctagtttttc tcatatagat actgtatatt 81841 tcttattaat atttattacc tgctgcttca tgtttctttt tgttgatatt ttgattgtac 81901 tttttattta actaaatttt ctcttttagt attggtacat aagaaagctg ttttattcta 81961 catattgagt ttaacaaaca gcgcagcata gtgtgtgttt ttggacaagt tacttccttc 82021 aatattttca tctttaagat gatattgtag ctacttcata agaataatga gatgatcttt 82081 taaagagatt aatacatagt tctcaattaa caaatattaa ttcttattat gatgattttt 82141 agttttctag acgttagtct actgaatttt cttttgtttc cagtagtttt ttcagttaac 82201 ttctgtggtt tccaaatatt gagtcattta tctctaaata aatatttagc cttctttttc 82261 caattaggga agattttaca gtgcctctca aaaggcagtt taattcagcg agaagaagtc 82321 ttggatcatt accatgtcag ctgcctttga ctttttgatg aaaatgtcag ccatgttcta 82381 atgagaatga atttggggaa ttaacttatg aaaaatgaat tatacaatat agttttgttt 82441 atttcattga gaagctcctg gaggacatgg tctgtgttat tcctgatgac cttgttgaaa 82501 attgaaggac actattatct tagtaaaaga aaaggactct gtcttaatcc tcactgtatc

82561 ccattcccta tcatgagtac tggcaaatgt tgtcaactaa atgaattaac cagaaagcat

82621 aatatagagt gcataagatg aaataggagt atttctgtga ttttctaaaa gtaagattgg

82681 cggaaagtgg ttaagtccaa attcctacca gtggccatta atcctgagat aaagatttgt

82741 tgggagaatc aatggaactt ttttttgtct ttgatgaaaa gttttcatat gttaaacatt

82801 ccagtgtgct taaagtgaat tttaagtgag taatgtggtt caattatatt gtatgagcaa

82861 gagaagatga gaaactctaa ccaaatagca aattgtttgt gaactaaaga ccagagagga

82921 ataaaagact taaaaactca ' ttcatgtgac tgcctctaat atgtgaatac atgatctagt

82981 tgtgattgaa tttttttttt aagcagcagc tgtgacttat gcaacttaga aatgttaact

83041 ttcaagtaga tcaaatcatc cacatcagaa cagaggggta atttattcaa aaaaagatct

83101 ccctattttc taacccatga tttgagtggg ctgtaaaatg taaacatgag aagtagggag

83161 atttgaggga tacgtgtagg gtagccaaat atgttctttt ttcttaaacc taaaaaatca

83221 tcctcaacat gagtctatta tatttattaa ccgagcagag ttaagggtct atttagggct

83281 ggtctaaaag ttaggccaag aagcaggtct gaacttctgg acttttgggt tgaggaaggc

83341 taattaaaac aagaactgtg agaaaaagct ttctttagaa ggctacgaag ggtgagtagg

83401 gttttggttt gatagaagat ggaaaaggag ggctttttga acaagggaaa aagatggaaa

83461 cagtagtact gaaaggagaa ataattaagg gatatgaaga taataatgga tctagataca

83521 tattaatgac taaatgtgta atgagatggg gaaatgggga agtgatatgc taggttttca

83581 gagggtcttg aaaacaaggc agaaagtttt catctgtgat gcttttgggt aagagtctcc

83641 ttctcacccc ccaagaagga tttcagttat ttaaaacata gcattttacc tttaaaacct

83701 gtttacatat tttgaaagac atttgaaaga gaaatacatt atattaatct tgagaaacaa

83761 cttgtagtat aaaagcaatt tctgaggtac cctgataaat aaaattgtgg aatagtggcc

83821 tctttctttt gatgatgatc taaagcaaat aggaacagtt gctgcagctg aaagtgttga

83881 taactgctga aggacagaga agacagccaa taaatacttg atttaaacca caagatttga

83941 caagtgagaa atgtgactta gaattatgat ttcttttttc ctcagtgtca cctaaatcaa

84001 tacgaataat attagaatga caaagtataa agtaaaaggc taaggctcta agggaagtat

84061 taggggggaa gttcaagaga tccaggttgg actgtggtta tcatagcagt cagaacacac

84121 attcctatga cctgttccta catctaataa aatgattgtt tcagagattt ctggtggaca

84181 ctcaatatct ggttttgatg cctgagatca gtcacagacc agtgaatacg gatttctaat

84241 ggcagtcagt attgacacct gagaaattaa ataggaaaag gaaatataaa aggaaaaagc

84301 ccgtcatctt acgatcatat tgaagaaact taacttgatg atttaatctt tttctcttag

84361 ggtcataatt agcctttgct atatgtcagt atttttaaat tgcattattc aaaatataat

84421 aatttctctt ttttaaaaaa ttgtttttta ttatttatag ggcaaatgga aatgacttaa

84481 ggatgcacgt taaagcacct aggtagtaat taatgggcaa tgacagtaag aggtattaac

84541 aaaaaactgc tgctaacaga ttattacaaa agtaaactag aaaagatatt ccgtgacata

84601 tttaaagttt attatggtaa tgtaataaaa gctgtcatac ttagtgacct agtgggagaa

84661 tgtcccaaaa caggatttct gatagagcag gcactataat ctccactggt gtagtcagtg

84721 ctgacttcag agacagtttg gaacagcgtt catatgtaga aacaatattt acaatatgat

84781 tatattactc tgcccaccca aaagccataa tgaattttca gagtccctcc cttccctttt

84841 ctctctcctt tcctctctcc cacccagcaa aataactgtg ctgtatgaga ctttgtgttc

84901 agcattgggt tggagtggtt agtaaaccag aaagaacagt ccctggccct cccacagtgc

84961 ttgcctttgt ggagcttgag ctctgtcctc caccgctcct ccactgtcag tacccttagt

85021 tttcagacaa gtcagcaggc agttagaata cagtatcaat actgtagttg taggtatctt

85081 gaattctggt gctcaagaat aagcagatat ggctgaatgt ggttgaagag gtggaaagag

85141 acttgtggag ctcttaaagg gatttgtgtt tactttcagg agccatagaa agaagataat

85201 ggtgctggtt ttaatgatta atttagctta tttatgattt tctttttatc tggtacagat

85261 tagatactat taatactttt atttttatct gttatcacca gggtcctttg ttttatgtat

85321 ggactgaagg gctattcagg gaggttgggt gtgggtaggg aacctcttaa gattgagcaa

85381 gaatggcaga aaatggagga gagggataaa agaggaaggg catgaatgaa tgaaaatgaa

85441 aatgtttaat tgaactgtgt agtctgtgag cccttggtct cctttgagga gaaaaagacc

85501 gaaggcattt ttacaattag atcttctcat actaccccag ggaaaaccat tagcccagac

85561 tagtttagct gctgactaga aatttgttcc ttggggaagg gtaagaaata catgactgtt

85621 gtgaacagac tgcttttata tttaatgttt ataaaatgag tttccataat cctatatctt

85681 tccataattc cagggaattt tgacctcaaa atagcatttg aaaaaatgta tggaacttaa

85741 atactttgaa gacataaaac acatctagga cttaataatt gtttgccgaa tagatgagga

85801 atttgaaagt ttgtaataaa ctgcaaatta tttggaaatc attctttgat gatataacag

85861 gaagggaaat tattgggctt tgagaaaatt tttatagaat ttcaggcttc atgatcaacg

85921 taagagactt acattacgaa gactaactac tatattgatg ctcaaactta cattttagtt

85981 tttgcttacc tttttaaaaa gtaaatattt tcttctgtgt acttaacaaa ctgcattaga

86041 aaaatctgat catttgtact aggcataatt tttgataaag tagtatacca tcaaaaattg

86101 agggttcact tctttagact gtaaacccta taaagcagac ctcaatctac ttttaatgct

86161 ctgaaaggta tattaggtaa gtttgcttga tgtttgctgt cttagaagag gcaggttgtg

86221 tgacacttaa gtgtgtgggt tctggggcca ggctgcctat atttgaattg tagctttact

86281 aggattccat ttggtggcct ttttagtgcc ccaggtttca catctgtaaa atgggattaa

86341 aaatagtacc tgccttcctc aagggattct tgtacagttt aaatatggca atacctgtaa

86401 aatacttaga aatacccatt attatggtca atattttact attaacttct ttcactatgt 86461 ctgtgtactt tttgtttata aagtattatt aaataaaata ccacaactta atttatttca

86521 tcttagcagg aagtttcttt agaagcacga aagattgtgt ttataacagt attcagtata

86581 atagtgtggt ttctctcata ttgagccaga tggcgttctc tagctacaga atgaggaacc

86641 ctttagctgt gtgtcatttt atgagccgca acatacatta atttaaaata aaattattat

86701 gaatttaaaa attgatatat agcaaatgta gagaattttc cccatggttg taataaaata

86761 atttttgtat catgatatgt aagagcaaaa gaataagaat gaaaacaatt atacttctaa

86821 gcattcattt tgacaaagat tactttagaa agtaagcaaa ttaaagtaaa acagaataaa

86881 caatgataag tttaattaga aatgtgacca ccattccctt ggtgctcagt tcagacttaa

86941 gtcctctatt tattttgtat tgtgattttc tattttattc ttactcatag taataattac

87001 ttgaaaatat tttataaaaa cattaacata tactccctgt ttggtcacac aatttggtgt

87061 tttatggaga gaaataattt tattcacaaa tatttattga acatctagtg tgtgtttatc

87121 tcagttgtgg accatgaggg tacaactgtg gacaaaacag tcctgccctc ccggaactta

87181 gccgtgaagg gaggcagata ataaagacac aggtaaaatt tgtttgtatg agggtggtaa

87241 gtactgtgga aaaaaaataa agagaagggg ggtataggaa agtttgtcat tttaaatagg

87301 atggtcaggg aagacttcac agaaaagatg acttgtaggc atagacttgg aggccatgaa

87361 gaagtgaccc atgaggctgc acaggagaat ggtgtttcag gcagagagaa tggcaaggag

87421 gctgttgtgg atggagaata gtaaggggag agtagtagga atttttcaga aacacgagct

87481 acattgcaca gggccttgta ggctgctgta aaattggcct ttattctgaa tgagatggga

87541 aaccattgga agttttcagg cagagtgaag tgacgttgct tccatttcaa aaagatgact

87601 ttttcagcta ttctgagaag aagacagtag ggagtagcag gaaaccagtg agaggcacct

87661 acaataatct gcaagatgat ggtacatcac caccatccaa ctacggtggc tgcactggag 87721 acattgagaa atggttggat ttttaattca ttttgaaggt agagccagaa gtatttgcta 87781 acagattgga tatcaaatta gagttatcaa ggcattgagt ctgaataatt tggaggatgt 87841 aattaccata agtgaggttt gggagtgctg tgaaggagtt gatttcataa ttgttgtggg 87901 gcaggagata agcagtttta tttcagatga gtgagtttga gaggaaaggt gcattttcta 87961 catacataag ttgtcctatt ccaagtgtgt gctatactta aaggtataaa aaataaagga 88021 aaatgaaata tggtgtgctc caatctgcga aatacatatg ttttgcatct gtaattgttt 88081 taaagataca tttgattgca aatatttgac aaccagtatt tctagctttt cttcttatat 88141 cgttggtcca tcgaatgctt ctttttctgt aagacaagag cgtatttttt gtgtgttata 88201 ttggtttggt tttcagacag atatacccag atattccatt acatttctat attccaagga 88261 cttatttttc aagtattatc aactttggat ggctgtgtgt ttatttcaaa atgatatcac 88321 agttgcccaa atatttttga aattctgttt ttgtgttaat taaagaatta gcttataagc 88381 cactctggaa aatcagtctt gtaggagttt ttaattttta tatattgact tctatacaac 88441 ctttgctttg acatactgta caccgatatc ccttaagagc caaaaaccat ttacatgcca 88501 cgtttgtttt ttcagctgtc agcagactaa tgatatggac taagaagaat gcatgagggc 88561 tctgcctggt ggagactatg ctggcgggcc atgatggggt cttcctgttc tctgcttcct 88621 gccccaggac taggggagga ataaattata tatataattt atttccaaag gatactttta

88681 aagtaaatga cacatattgt tatatttgct aaaatgggct attgtggttg ggtgtggtgg 88741 ttcatgcctg taatcccagc actttgggag gctggggcag gtgacttcca cttttcatta 88801 tattttgcat agaagttact gcattggtct gatgagaaag aaaaactgct ttaaattcag 88861 gccatttctt ccatcaagta aaaaaaaaaa aaattctccc tggagtaaag ctttttgcca ^, 88921 gtagggttct gtagcttgtg ggatgtacta ggaaaaggtg cacaaaaatg tgaagcacat 88981 gaatgaaaga atccgtcttt tagcctgtgt gtgaaaagcc tggtttcttt ttcatactgt 89041 tataggaagt atttcagatt ttatacatat ttgctttttt ccattttgaa gtggttgctc 89101 tgtgtattct tcccaaaggt atttaaaatg agaatacttc tgtggaatgt aaatattaag 89161 attgatgtct aaaggtcatt tttaaaattt aaaacatctg ctctccttca tacttaaata 89221 tttattgaac agaagttgta taagctgatg atgagtcttg atctggaata gaccctagtc 89281 tgtgatacca acacagattt gaatgaagct tgccaaggtt agcacctact aggtaagttc 89341 taccagctgg gggtagacat catcagaggt ttcctcattt ttccatacct tgtgtcttta 89401 taatgaatag cttatgcagg catctttgtt tttgcctttc cttgtaatac cacacatgca 89461 cggctgtgtt gttgggaact tccaggaaaa gcttgttcag gtaagtagag cgggagagca 89521 gaaattgaac taatttgtac taccgagtaa ctgtgctgtg ttgcttcttt gtccctagat 89581 ccaattcatt ggcctcagtg gattctgtgc tcctaagtcc cagcgacaga acatctactt 89641 agtcattgat attgggcctt ctgcctttgt tggaaatggt tgctctgtgt atttatattc 89701 tttgttcatt catcgtaatg atcctgtttc tagatcctct ctgatttggt attaattgta 89761 aacttgctga gcagagaagt tgtttaagat ggctctaata tgacaccttg gtccttgatt 89821 tattttgctg ctttttaaaa tggacttata gtataaagag gctagtgtaa gaaatatcat 89881 tgaggaggca caagtatgtt gttggaatta agtcatttgg gtgaggagat aaaagaagat 89941 ttaggtaggt catgtaatta aagggatgtc catgacatgt ggatgttcaa gaggtgggaa 90001 ggaaggaaga ctggatgact gtgattagag tctgcttcag ggtagagagc ttacctttta 90061 ttatctttgt gccttagggc ttggcactgt gcctgatgtg taggtgttca ttatatgatt 90121 ttgtgaagca gtcaaagatg gaataactat caaataagat gttaagagta atctctaagg 90181 ttaagaggaa aaagtaatga ttacattata aatactaagg aaacagaagc agcaaagagg 90241 aatagaaggc aaataaggat tttaaaaaaa cagttaaaac atacccattt aacttgaatt 90301 gaatgtcgtt tgattacaaa ttaaacgtag taaactgaca atatgtattt gatattaaac 90361 ttctttacag tagtaaatat taggtattga aatcaagcct attttttaac cataaaaata 90421 caggactttt aatatgcccc ttgtctagac caactgaact ttattttact ttaatttgaa

90481 gtttgtattg gataaaatat tttggtatct taataatcag ataccagatt tttactaatt

90541 aaaataacta taattgaatt ttctttttga atattttacc attcaatgta gtattaacat

90601 ttaatattat aagttaactg ataaactgca tgcataggaa tttgtgtgca ttaattaagg

90661 actgtcatgt aagtgttctt aaactgaaga gttaattgat taaaaattga aaatattcaa

90721 atgagaacat gctgagaaaa tatttcatgg gaaaatggat caggtgaagg tttgtgagca

90781 agaaactatg aatgcctttt aggtgtgaat gataagggat taaaaatcat ttaagacttg

90841 tatgcttata tatcttatct gtgtgtggat ctggaacagc taagctgcta cttcaactaa

90901 gaccagacat gatatgtgag ttatataatc ttatgtgatc agaataattc ttcccaaaag

90961 aaattttgat tgctgtttcc ctgcttatga caccctgttg cctacaagat gacactcaac

91021 tcaggcgggc acacaggacc cttcatgatt gccctttgtc ttgctttcag ccttatctac

91081 acttcatctt tcacctgtgc tccttccttg tcccccactt tccccagatt tcttgtaggg

91141 aattttctgt attcctttaa atatgttgta atattttcta cctcatttat ttgctcaggc

91201 tgctctttct gccttgaaat cccctgacat tatgaggtcc taaaaatata acttgaaaaa

91261 tatttaatgg tttctttggc gtcataccat gtgtattaaa agtaataaac aattgaaatg

91321 tatattctct accttggtaa caatgggtaa gagtatagaa atgacttact catatattca

91381 ttcaacaaat gtttactgag cgtctactat ttaccaggca cagttcttgg ccctggagat

91441 ttgagattga gcaaaataga caaatctctg ccaccaagga acttttacac aagtggggat

91501 ggcaggcaga taataaacgg atatgaccag gctgaatttc tgaggaatat aaacaaaagc

91561 aaggaaaggg gaaaaacgga tgggaggtgg gtgttgataa atggtcaggg aaggcatttc

91621 tgagaaggtg acatgtgagt gtagatgtga aagaagggag ggagcaaacc atgggaatat

91681 ctggaggaag aatgtttcag gaggagggtg caacagcctt gagtatagac ggcttagtgt

91741 tcttaaggaa caggaaggag ttcatggtgg ctggagtgga atgagcaaag ggtctggggg

91801 agaaggtcag agaggtcgta ccttgctggt cctggttggg gtgtagcaat ttactccaag

91861 tcagaagctc tttgagcttt tgagcaggat ggtgataatt aaaaaaaccc tgcctgttgt

91921 gtagaatgta gactgcatcg ggaagaagaa tgtgagaata gctgcagaaa gaccagttag

91981 gaggctgtgg tcatcaccta ggtgagatgt gttggtcgcc tgtattagga tgggagcagt

92041 ggagctgctg agaagtagtg ggatttaagt atgttctgaa aggagagcca agggaactag

92101 cttgttggag tggatatagg gtagcagagt acaatcaagg attctgaagt ttttcactag

92161 agaaatttga gtgatgtaaa ggtaggctca tattgagatg ggggaatatc ggaaggagga

92221 gcaaggtttt tgagaggtta tggaatcagg aatttgattt ggttttgtac ttcttcttct

92281 tttttttttt tttttttttt tgagacagag actggctctg ttgcccaggc tggattgcaa

92341 tggcacaacc tcagctcact gcaacctccg cctcccgggt tcaagtgatt cttgtgcctc

92401 agcctcccga gtagctggga ttacaggcat gcaccaccat gcctggttaa tttttgtatt

92461 ttggccaggc ttctgtcaaa ctcctggcct caagtgatcc gcccacctca gccgttttgt

92521 acagcttaag tttaagattc ctattatgta tcctaaagga tttgtcacat aagtatttgg

92581 atatgtgagt ctgaggatga gggaaaggta ggacctggaa atacaaaatt gggaaccctc

92641 agtttactga cggtacttaa ggaagaggtt aggataggag tcacctaaag agggagtgta

92701 ggcagagatg gcaagaggcc caaggtcccc atcctgggac acatgtcttt ataggttggg

92761 aagggaagag tgtccagcaa aggattctga ggaggcagag ccagtgaagt aggaggaaaa

92821 ctacgggagt gtggtatttg gagtcaaagt gaagaaagag tttcaggaag gaggaggtga

92881 tcaattgtgt cagatgctgc tgagaggttc agatgaggtc tgggaattgc ccactggtat

92941 tgccattgag gaggcttgct gacctttagt ggagtggaga ggatagaaat ctgattaaaa

93001 tgggtttaag aatgaatgga ctgaggaagt ggaaccagtt gggatcaact cctctttttg

93061 aggaattttg atatgaagag gaacagagaa atggagtagc agctgagagc ggttcagaat

93121 caaggtagat ttaaagtagg agacaacttt ggaaataatg atagttttat tccccttttc

93181 ttctttgtta aaaagaagac atgacttacc tgaggaaatt cttagcttta atatctacag

93241 tcgctataac atgagaaaat tgtcattgaa cgagatagca ctttttgcat tgtggtgcta

93301 aaaaaaaatc tttatttttg tagagatggg gtcttgctgt gttggccagc cttgtcttga

93361 actcctgtcc tcaagcagtt ctcctgcctt ggcctcccaa agtgttggga ttacaggtgc

93421 gagctactgt atttggccta aaaaatcgtt ttataaagca tcagatttca gtgcagttac

93481 aatgtgcttt cttcctttag cttttcggat gttacatagt gcctttgaat tatatggagc

93541 tgaactgccc catgtgagat tttctataaa cctagaagta atttcagaat aaaaatttta

93601 cacaattata tgtctgaaac aaaattggtg aaagttctgt tactctaatt cttgtagaat

93661 atctaaatag tattaaaaga atcaaataac ttttccaagt aattccttcc acttaaaaaa

93721 aagtgttgcg gccgggcacg gtggctcaca cctgtaatcc cagcactttg ggaggctgag

93781 gcaggtggat cacgaggtca ggagatccag accatcctgg ctaacacggt gaaaccccat

93841 ctctacgaaa aatacaaaaa attagctggg catggtggcg ggcgcctgta ttcccagcta

93901 cttgggaggc tgaggcagga gaatggtgtg aacccaggag gtggagcttt cagtgagctg

93961 agatcacgtc actgcactcc agcctgggtg acagagcaag actctgtctc aaaaaaaaaa

94021 aaaaaaaaaa aagaaaaaga aaaaaagtgt tgcatgggta tgtcaattaa aaaaagtact

94081 taaagaaaat tagctgattc gtgctacttg atgttttact tgatgtttgt tctgataggt

94141 aggattaatt ctacttaaaa ttatactgtt ctggtactac attttataag tgtttacatg

94201 ctcattttaa tttcctgcta attgcaatga tagcacaata atgaattcta cctataaatt

94261 acattatcta ctattaaaat acagtttctt ggttgtgaca ctttatgcta ctccacaaag

94321 agggaaaata cttttgtaaa tgaaaggaag agcagaatgg tggtgggttt ttctgactgg 94381 tatttaacat gtggatagat tcttcataca tagataatat gcatcatggg tgagtcacca 94441 aattttaata agaaaaccaa ttatttgtgt atattttgaa agatgatgcc tcataatttt 94501 attcctcctt tgatcagata ggacattttg tttagtaaaa tttcagaaga cagattcctg 94561 cttcctgatt ggcatcaatt atcttacaac acccccaatt tttttggaaa tgtatgcctg 94621 ccaactcttt atttgaagag ttatttgctt gctttggcaa aattgactct tgatgagtgt 94681 tcccctcttc tagcatttgc tactcactaa attttcctcg tgtgtgctga tggtggtaaa 94741 aactcttgtc acctttctaa tctgtttggt aaaccttatc tttgatactt cattatgtaa 94801 ccatgggttc tcagttctct ctcgactctt accctgcagc tttgtagtta caaggggaaa 94861 tatgacagtg agaaaggaag aaaatccaca gagagagaag agactgtgca ctgaactttt 94921 tcattaaaac ttttataaac tataaatagc tcctttcacc tttagtcaaa ggaaatatca 94981 agaaggcctg tagggtagct ccctatggct gtttaaaaag tgtttgattt ttatggaata 95041 gtgcaaaagc aaattgcaaa gtcaatagaa acaggaatac tggagaagaa ttgacaggaa 95101 ctgataaaat taaggagtga ctgagaaaat gagtctgaca gcccatggct gatacagaag 95161 aaagtgccag actgatctga accaagagaa ccaagacaag tacaagccct cctgcagaag 95221 tacaggaccc aggatgggag tctgtggttc ctaacagctt agtgcctgat cacacttaaa 95281 catacattat gcttatcact ggattgcaat aacgcttgct ttactgaaca ctattctaag 95341 tagtttgtac atcatttagc cctgcagcaa ccctcttagg tataggaact attctaagta 95401 ttcccataag attggtacct tgcccaaggc ttggatcagg aacacagatt tgtctgatcc 95461 ttgagtttac attattctta atctagctgt tctgcatctg actttatgtt gaagttagtg 95521 ccccagtgca cctgtttata tggcttcatc tgtgatgttt tctctttcct ccttatcaaa 95581 cctgttttaa accttagagt tctgagttaa ataaccttgg tgggtgtggc aggaaatctc 95641 tgaaacaagg tggatccatg ctgcattgtg attccttgca ttcaggtggt cctgccaggg 95701 ctgcaattac taggtgccct tagacggaac tagttatgat ggggtcaggc agaaggtacc 95761 tctgtgtttc atgtgagctg aatctttcct aaatgattaa gagaaacagt ggttattgag 95821 ggaatcatgt gcttcagggg aggactgata aaactaagtt aatctattag gcctttgtat 95881 tgtgataagt aaaactttac tttccctaaa ttagaataaa tattggggag aggaagagag 95941 aggtgtaaag atggtctcca agttcctggt gactagctgt tgtaacagtc cccaaagcta 96001 tatttttctt aacataggtg gaaaaaaagt ttggttgtct gtgtccaggg caactaggaa 96061 aaaatatgtc tctgtcgcca ggctggagtg cagtggtgtg atcttggctc actgccacca 96121 ccgactccct ggttcaagtg attctcctgc cttagcctcc cgagtagctg ggattttagg 96181 catgcaccac catgcccagc tgatttttgt atttttagta gagacggggt ttcaccatgt 96241 tggccaggat gatctcaatc tcttgacctc gcagtccggc caccttggcc tcccaaagtg 96301 ctaggattac aggcgtgagc cactgtgcct ggcctgataa aacacatctt tgaaccatat 96361 gttcaaaccg tacttggagt acttggcaga gtacttggag accctggagt ccatccagat 96421 aatcttctac cagaggggag aaaagaacct ttattcataa aggttcaaat tacagaaatc 96481 attcgaatct tctaggctgt gctcctatga tattacaaaa gttctttgtt gaattatcaa 96541 attacatcca tatatagata ataactctgg tgctaagagt gatcattgcc agtctgtgga 96601 tatacatgca tctccaaccc ccagcatttt acttattgaa ttctctgtga ctctagtatt 96661 cagaatttga ttacctaaag tgaaaatctg ccaattttgc ctgatctgtc attctgaggc 96721 cttctcaact tgaactccca tagtattttt ctcttacctt ttctatgaca attattttca 96781 tattatattt atttgtataa gtatctgtga gagcagcagt tgtgtctcgt tcatctttat 96841 acctcctgta gtgattaata caaaactcaa taaatggttg gtaaatgaat agaacacaga 96901 aaaaatcttt cagtcgtgaa atacagaaaa tgtagtttac tttacaatgt cttcttagca 96961 ctttctttac atattccaca aatccctagt gtacttcttt ggctttttcc aaaatcccct 97021 cgatattact tgtttaattt ttaataaccc tttttccttc gtggccagaa gcctttaaag 97081 gtcaggatcg gtgcaacaaa ccactttcag tttcacattt tttatcacat ttcttagcta 97141 cttatgtgtg gcagtattta ccaacaattt gtaggtggta tctataagga tagtcagttt 97201 atttcccatt aggtactgtg cctaaaattt gagcatgtgt taccacagca acttggatgt 97261 ctggttaaac taattggtca aagcattcag gcttcctgca agttcagata actgattagt 97321 agctaatgtt ctatggcttt cctctataaa ttataagaat aaaaatgtta atataataat 97381 actcaattta gtacaaattt ttatatagtt aagtgtgtga agtagctttg taaaaacctt 97441 gactgctatt aaacccatcc tttcctacca ttatataagt taacatctat cttgtatctc 97501 cctttcctag agtttaaaac aagacatcta ttaagttatt tattctactt ctggtgttag 97561 tggttcacag tagctccgta tcctttctgt acatgtatcc ccatgggtac cagcactctt 97621 gattataagg agctgaaaat caacttgaag tggctaaaga aagaaataga tttattggga 97681 agagaagtat tgcaggatag aaacaagagc tgaacaactg cgctttagaa agtcaggcat 97741 ccagcagagc tagcacctca gcgggtgcta tctccatgtt atcagtgctg tctgtctcta 97801 tgctaccctc atctcctaat tttactacct gatggcttta gggtctgagt tgagcttctt 97861 tacaggtcga gagacactgc cactggctgc ctctaagcga atgctttctc tgctttgcta 97921 ccatcaaggg tggaggggag gggcgcaact gagctctggc tgaaaaagtc ccagggaagg 97981 attactctaa gttggattcc ttgtctgttc ctggataagg tgcagccctc cttagactgc 98041 agtggatggc gtggggtgga aaaaccattc cccaggaaga gagaaaaaat gtgctggcca 98101 ttccaaacaa ttcggttcta cttcttttta agaaacagga acctatccta ttttaataaa 98161 cactcaggga aagcattcca caagggatgg caaaaaggat tcgactaata tttgggtgct 98221 gctgttgtca ctatgttacc gaatacaaaa gggttgcaga gtaggttaaa gcatttcaga 98281 gttgttaata tccctgtgac ttatgcatgt ttgtagtgaa cctgatttca ctctcaccca 98341 gtgatactga actgttaaat gatctatgat gaatcttctt tagccaaaag cctttttttg

98401 gttttctttc tgttattgaa gagcgatgca cacatggttt tggaatgatc taaattatat

98461 cagtattagc ttgaaaaggc aaatactaaa acaatgccac aggaaagtca attaaattat

98521 atagggatac acattttaat ttcagttttt aatgtcttca gttggttatc ctttatttgt

98581 cctaaatatt tattgtcgaa tatccagcac tgttaaccat tctttcccaa gggcctgctt

98641 cctattttat ttcttaggtg tatgtagagt gagacaaaag aagtatatta cttaacaaat

98701 actttttatt tgagtatttt caagtatgta ctacataagt ggcaaaggtt ttctagattt

98761 aaaactgtca aatgtaatta aaaattattt ctgtatgttt atttggcagg ctcttttaag

98821 agggttttct tccttttgag attttcctaa tttttcaaac taagtgaaaa tttggaaagc

98881 tgggacaaag tccctaaaag caataaaact cacttataac ccccaactag aaaatatgtt

98941 ttctgttgtt gttgttgttt tgtttttttt ttccttttca gagtttattc agaaacttag

99001 gtaagttttt gcaaatgaga cttagcttct taagcagttt tttgatagtc atgggattgt

99061 agcctctgtc ctcaatggca ttttgacacc aggaagagag aaaatcctca catcttttct

99121 cagtgccatt tgcctttctt cttgatgcta tcccaaggat tttatgtctg ccattgaggt

99181 cttataattt aattcacatt tctcagatca tattagtgct atacatttgg aactctgtga

99241 tactgttatt tcgtggatgt ggtcataata aaatcacttt tacatccgga tcttctccat

99301 gctacacact tgaggcatga caccacatca gaactccagt tgtgtttctg cttagggtgt

99361 aaaaatgaaa aactgtgccg tgcccatgtg aatgcccatg cattttagat atcacctgaa

99421 taaataagta ataaatacat aaatgtgcat gtatatgtat gtagaaacca tatgtatggt

99481 tgatatatag aaaaccagta tctgttttaa tgcagacaca agtcttttga aacaagggtt

99541 tgtaattgaa ttaatgagga agcaaaaact gagatgcaga caaattatta tccaggataa

99601 tttgaaacaa gggtttgtaa ttgaactaat ggggaagcaa caactgagat gcagacaaat

99661 tattatccag gataattgag ggcatacaac caggaaacac aacatgtagg gatgaggaca

99721 tttatttcat aaaaaggagt aggctgagcc agcagcggtg gtgcacacct gtaatccctg

99781 ctctttggga ggccaaggag ggtggatcac ttgagcccaa gagtttgaga ccaacctggg

99841 caacatggca aaatcctgtc tctacaaaaa atacaaaaat tagctgggca tggtggcatg

99901 cacctgtggt tccaattact cagcaggctg aggtgctgag tgggaggatc acttgaagct

99961 gggaggtcca gcctgctgta actcataatc gtgccgctgt acttcagcct gggcaacaga

100021 gtgagaccct gtctcaaaaa gaaagcagtg ccctgaaatc agattttttt gaaagccagg

100081 caaaaataag atttttaaaa aatgatagtc tgcatctacc agtttctgtt atagagtcat

100141 aattgtcaac tttacacgct gcttcttgac aaccttaaca atctgaagtt cccttgctat

100201 agctctagct ttggatttta atttccaact tagatgaagt tcataacaaa acattttttc

100261 acctgaacat attttctgca gttcataggg atcagcacag gatttatctt tagccaagac

100321 atgttacagc atccattgta tgcaaaattg tatcagcaat gtagggaatg cagagatgaa

100381 gaaaatgtgg catgtatgtg tgtttattag aattgtgttg tttttattag tgttctggat

100441 gtgtaggttt tgaatggtct tcctcaatat cattttccac ataagtcctt tggtttttag

100501 ggtgtaattt aacagaatgt aaagttttgc tgggaacaga tttattgggt tgtgatagaa

100561 tcacctatgt ttattgataa agttagttct tttttcccct acagaatcaa gaaaacactc

100621 aaagttgtat aatattagga ggaaaatctc aacattgcca tgcaatgtcg tgcatgacat

100681 atggataggt ttggtattgt ggttaagaca tggctgttaa acattcagtt taacagattc

100741 ctccagaatt tcacggtgtt ttgggaaagt attttagata agtgacattt cttcaaatat

100801 atgagattgt aagtagtgag tgacatcaga agagaattaa gtcataaagt ttttagggtt

100861 cacaaaaagg ttggggttta ggcttactaa aacaaaatga acatttaaaa atcaataaca

100921 tgaaatttta ccataaaaat ttacaacata aaatagatta ctaatatatt actaaatata

100981 atctatttta aaagagaaag tatttgctag ggttatatgg aattataatc atttgaaaag

101041 caacttattt ttggaaaatt tctgttttct ttattacttt tgaaaataaa tttataattt

101101 tttcctttct tttagactta aaagttttaa tgaagctaat tcataaagta gctgattatt

101161 atagttagat tcgtatatat aaagtactct tttcttccct catatttaaa attttcttag

101221 tgtttctttt tccttgttct gttaaaaaaa agtgttttcc cttcacaggc ttttggtaga

101281 aaaggaaaaa aaaagataaa gatagaaaaa aagtaattct ctatcccttt cttcagttct

101341 tttttccagg ttttaaaaaa ttgtttggcc ccacctgtcc ttcagaccct atttatgtga

101401 agatcagtca tctggcagcc tcttgtgtct gagatagctc cacgaaggct gacatgaaac

101461 aagggtttct gagtactgca gagcctgtgg agtaaggcct acatgttttc cactcaggag

101521 aaagttcatg gttctgcttt gaacccacct gttgactcga gccattcaca ccctcttcta

101581 ataagcctga ttatctagtt gcccaatacg gggatggctg aggaagcctg tagcaagaag

101641 actgaggaga gtgtggtgat attagaagga agaggcacat atagggccat aataagtcga

101701 ttttgatgcjt aaaaagagaa tgaatcataa aaatgaagca gaagaacact tagatgtcag

101761 attattgaga ttaggagcca gttggccctg tatacctact gttaaacccc gagggctgct

101821 gctgatgttt ataattggcc ccatcatcag ttgaagatta gattgtgttt attataatct

101881 cttttaaaag tcagggaagt gcatactact ttttagaatt taaaaaagtc tcatataaag

101941 acaggcattt caaaggatcg atttttgttt actcacaaaa atgacctagt agatgttagt

102001 cttgtttttc tctctgtcca ctgagattgt ttttacaagc ctttttgtct cttctctttg

102061 aagctataat ttttatttta acctctactg ttgttctttt atggcatagt ttcagacatc

102121 tcaatggcct ctaataaaga tattcttaac accatagatt gtgaatcctg tatgacataa

102181 tgattaattt cctgcagctt tgcgctctcc ctgctctctt tacttctgct ttatagtcag

102241 acttggtgtc tacatgcttg ttgagactat tattttcccc tacccattcc tcaagctacc 102301 catccatttc cactctacat atgtccacag aatttgtttg aacttctgtc atcagcaact 102361 cttcttactg tttatttatt cagcaagtac tgagtgctgt cctaggggct ggggaaacac 102421 aggagaacaa acgagaagtc catgctctta agcagtttac attctagtgg ggaaggaaga 102481 caaacaaagt aaattaatga acaaaaacag tgtaatgtga taggggaggg aggagcaaca 102541 gcagaggaaa gccagagaag gactctgaag aggcaatacc tgaggtccaa ctgagtaatg 102601 ggaacaagtc agccaagggg ttatctggga agaacattct aggcagagag aacagcaaac 102661 agaaacattc ctgagaaacc agctttgagg aaaagaaaaa ttgtccattg tgactgaacc 102721 atagttggat gagtgttgtg ctcagatcca cttggtcagt gggtgcctag ggtgaacaga 102781 agtccttccc gtccaggtct cagtcagtga ctgatcagcc cagggataca aaagcctggc 102841 cctcttgctt caggggagac taatgctggg tgtagttttt gtctgaggcc acattcttcc 102901 ttggcttttc ccctccctgt cctgcctccc catttctttt cactgagggc actgccccca 102961 ataaattgta agatctgggc ccagctctgt ttctaggaaa ccctgaccta ggcatataag 103021 caaacttttg atctatcatc tgagctccag acccttagac agctgcttgt gcaacatgtc 103081 cacttggatg ttcagagata cctaaaactc aatgtgtaaa aaattgagtt tataatagtt 103141 tcctcttttc ctcaagcttg tattcttcct gtgttcactg gtttacttta tgaaccagcc 103201 ttttacctag ttatactaga gaattcagta tagattttcc ctttccatag acttcatgtc 103261 cagtcactca gcaggtaacc catggtgaat gcctcttacc tctgttgttt ttccacccac 103321 attttcatgg ctttagttca gggccttgtc tgaaacacta gcttagcttc ccaagtggcc 103381 tccccacttc ccttccttca cctctccaat ccatttctac accattaccc tgtcgtaaga 103441 tgaaaaatct catccagcca ctcttctgcc tctagtcctg tagggctttt ctattggata 103501 aaatggcaac ttcatatagg ataaaattcc caacttttta gcatggctta cagggccctt 103561 tctgccctgg cattgagcca cctttcttct gagccttcgc agtggtgacc actgtgagta 103621 tggcttggtt atttcctcat acagcttcca gtttcaggct tcatgctatt ccccaaatgt 103681 ccttcttctc ctgggtagta ctggaagctt cagctttacg ttacctcctc tgtgaagtct 103741 ttttttgagc cacctaagga atattattta tactgaatag agcactctca aaatactcat 103801 ttcagtgtat tataatcact tgctttattt ctaatcactt aaggcattca ttgaatgcag 103861 agcacatggc tcttcacatt gctaggcaca ttagcacgtt tgctgaatga atagatgaaa 103921 gattaaagga gaaatgttac tgtgtttgtt ggtttttata caagatatct tagtgaacac 103981 aaacattgta cgaatgttag gggaaagggg attgcctaag aagaaccttt agccctaaaa 104041 tttggagttg ggaaattcat taatttttta aatgttaatt taatatttgc tagatgccta 104101 gcattgtatt atgtggtatt taagtaaatt ttgaaaaatg caattggcgt gatttatcaa 104161 gggccttaaa atggggaaaa tgccaacagt acaagagagt tttatgaggt ggtgtatgat 104221 taaatcttga atgactcaaa taagaagtgc tgttggttct ggaaaaggtg tctttgtggg 104281 ctggagggat aaccaatcac aaaaaagtca ggttcttgaa agacctgttg aagtctattc 104341 tgcaaaaatg atgctcatat aattcaatag ttttcagata ttaaggagat agctttctct 104401 tttgactttg ttgaagatga aagtatgtaa tatttgtatt tgaacaataa ctttttaaaa 104461 agattttaca tgagcttttg tgttgtaaga aaacaaagtt gaattatctt cacagtgtca 104521 ttcaaaatga tgaaggtgaa gatagtttgc aagtgggaga aagaagagat gattcattta 104581 aaccaattag gatgtgaagg gaaaacactt tgcctgaggt ttctcatcat cattgtatac 104641 cctagtttgg ggagctttgg gaatatcgac cacttatcat tgacacagta gttaccgcct 104701 cttgtaattt ttaaaatacg tgaatattta caaggttaga tttcatgcct tttttatttc 104761 ttgcctaagg tatttctcag ttgtattgtt gtatcttaat ctaatttatg tccttttgtg 104821 attctgtgta ccgaggacag gaactccttt aaaaaagagt ggatcaacca ctctcctgta 104881 ggggtcgcta tgagagtagc agtctggcat ccttcctttg ccgcctagca ccttgtggca 104941 tgacttggca caatttgcct aagggttgtg agatctggct tgttttggta ttttattttt 105001 cagaatggta tgagctctaa gtccaccaaa aattctgcaa gctcataact atgcattctt 105061 ttactttggt tctgtgtatg ctgcatatgc tgcacctgtg cttttttttt ttaaccacat 105121 atttggtgcg tggttatttt agacttctca tcatactcca tttgcatatg acaaatatat 105181 acacgtagac accattttag cagcttttgc agcatgcatg atggtggctg aaacttggcc 105241 ttctatagga tcccagatta ttatttaatg gggttgtcac tcaggacact tactggcttt 105301 ctccagtgct cttaaaaaat tgaattgagc atgatgaggt gcatcccctt gattaaatgt 105361 ttttcctcct atgcaatcac cattagctgt ttggctccca ttctgtattc ttctgaagca 105421 gccctgcatt gcaaatcaat atctttctga aaagacagtg tgttgtgaat tgccttgaca 105481 gcatatgcac ggttactttg gctgcaatgc tgctgcagag cccggttact ctgccttcgt 105541 gggaactcca caggcaagtc catcgtgttt ggaaaaaaaa attagatttt ttggagaaaa 105601 taattgagct gttaaagcta ttgatactga atgttagcat gtcctttgag ttcttctcaa 105661 cagtttttgg tcttattcca ctgagattag cttctcttag gggatttctg ggcttttttt 105721 tttttgcttg cttatgcatc cccctctctt ggttgtagta cggccgtacc atttcagctt 105781 gctagtgcag aaagatgtga attcagttgc tgtatgagcc tggcctggtg caaacacatt 105841 gctagagaca tgttaaagag ttccaggtga atcaagcctg agggagacaa cagcaaaacg 105901 gtaagacaga gcatgcttaa aattacagga ggggttttaa tttggagcat ctcggcaagt 105961 ctgaatcctg actcactcat ttacaactta aaaaggattc attttatgca tgtcatttta 106021 ctcacttcct tctatttaac tgccagaaac atcacagatt gataaagggg gtatttaaat 106081 tagagactga ctggaggtta ctcatgggag agtcttttga ggctcccgag gctactgctt 106141 gtagtttgta aacaccagta gcagtgataa gatggggaaa aggtttaacg actgcttctt 106201 tgccatatct gagtcttatt ccttctgaaa ctagtcttta tttattacag ctgaaagaga 106261 tcttacattt ttttttgcct ggctgtgctt ggctgaatgc cctctgagtc aagcaagtga 106321 aggacgagag actacttttt ccatttgagt aaactgatgt ccatgaattt agctggattg 106381 gatctgagta gaataaatat ctctaatata ttagagacct ggggcttcct ccctgctcat 106441 cctatttcct tcctttttgg atcacagaaa tacacctgct ttaagtgtgt actgctgagc 106501 agaggtcagt gtgctggtat tttgcatcat tacacctgta gtggttatgc ttttatgtac 106561 agaagtgata attcttcgtg cagttctgcg tgaagtgcca gctctaatag tagactatta 106621 gcattttgga tgctaatgga gaacccctgc attcatgaag gaccgtggta gcagacagcc 106681 tactccaatg aggcttacct gcttgtaaag cagataaaat tgagagatag gaatgtaaac 106741 cttgacgtct tcagagactg aatttttgtt tcctttgtta attgtcacac agttgacata 106801 tttgatgtgg cgggggtttg aacttgaagg acatgtttta atagtgttca aagtgagatt 106861 aataacatta cttagtccta gtgactttat atggatccac ctattattat ataggtgctg 106921 aatgttaagg atgtcagcat ttgatttttt gctttaaaaa tattccactt gtgtatagtt 106981 taattaactt agtactttat gtaaaatgta gatggtgaat gttaaaaaaa tcagtagctt 107041 gcatgttggc tattatacag aactggcatg tagccagttc tgtataattt tgtgacataa 107101 gtaaatttaa gaaagatcgc ctgattagtt gataggctaa ttgagagaaa tatgggtaac 107161 tgttgtggtt cactatgagt aaatttcttt aaatggtgca gtgcttctgt attcactcaa 107221 ctatttactg ttgaggttgg acattgattg ttgggagtga atatttggat tttcttccaa 107281 agatagatca aatttacctc tctttttttt taaacttttt ttttctgttt ggaagatgat 107341 gcgccctgtg tttactgttt ctttttctga gaatcttgtg ttttagctat tcatattttt 107401 acctttactt tgtgtgagtt gtgaggattt ttttttcatc ctgtgacaga aggaattgta 107461 agtttgcgaa aagtaatttt taaaaagtag agcaataacg tgactgattt tacaatcata 107521 cgatatttct ctcattctgc aaatattgat tagccaccca ctatgtgtaa aacattgtaa 107581 gacctgctgt aaaggaagta tggatgaaac agtacatttt cctgaagaag cttagatata 107641 gttgtgttag tattttcccc tggaatacgc cccattatac tttctcatgg atagtcagtt 107701 tggtgctttt taatcctctc cttttaaaaa agcatttttt ggttaaacat ttttggagtc 107761 tgttgtgtaa tagtggtgag taaaacagat ctagtcctgg ttcttatgga acttatagtc 107821 tactatgttt tttttttttt ttttcaattg agccgagggt ctcactatgt tggccaggtt 107881 tgtcttgagc tcctggactc atgtgaccct cctgctttgg ccttccaaag tactgggatt 107941 acaggcatta gccactgcac gcagctacag tctactttta aaaatatttc aaagagaaaa 108001 tatgtggcaa gttttttttt ttcattttgg tagttatgaa ggagatattg tatgctttga 108061 tattttttat tgtggtgaaa tatatataac acaaatcttg ccattattac catttttaag 108121 tttataattc agtggcatta gatatattca cagtgttttc aaccatcacc actatccatt 108181 tccagaactt tttcatcaac ccaaacagaa accctaccct gctctcatta aatagtaact 108241 ccccattccc cttccccctg cccctggtaa tcttattcta ctttctgtgt ctgtgagttt 108301 ggcattctag gtacctcata gtagattaaa ttgagtcata tgtatttttt cttttgtctc 108361 tgccgtgttt tagcatgttt tcaaggttca tccatgttgt atcatgtatc agaatttcat 108421 tccttcttaa tgcattcttt gatttttata tgggatagac agcagttttt cctcatatga 108481 tgacatgaat caagttccta tatggacatc gtaataaata ctttagatat actaaaatag 108541 cctatgggaa agggcaagga ataaggaata gaaatgcact gagaggaaga gttatggata 108601 tattatatat tattttcata tatttatcta tggatgtatt ataattgaga tgctaagatt 108661 ttcacatcaa ttctttgctg atagcagcat tcagctgaaa taattggaag ctgggccatg 108721 gcttttgtca ttattaacat ttgaatttca cccactgtac ttgtgtctcc tttctctatt 108781 ttacttcata agcaaagact gatcatgttg aggtcttctt acagagtcag agactcttag 108841 agctggcagg tactttagaa attgtgttat ttaattggtt cattatcatt cattagccaa 108901 cgtgagaggg aaactcagtc tcctgctgcc cgccatgggc cttcttttac tccccacccc 108961 tgttttcagt ggaaacaacc agaaaacccc aagtatcctc tgagtttgac agaaatagta 109021 gagggtgtaa atttgatgcc acattaagaa gttttccgtt ggatgaggta agcctagctt 109081 catcaataca gctttctgtt tctcagattt cttcctgata ctgcttccat aaatccagat 109141 ggtttttctg aggggaccct ttttagaaag ccaagttaag gcctcagtgc tgttcattta 109201 ttttctgtcg accattttga cagttcttac actgggtcag tcagcagttt atatccatgc 109261 ttttaactca ctatccaggg gacccaacca tttatagagg aagaagattc aacatagcaa 109321 tatccaatac ctgagtcttc ccaaataagc ctgctccttc ttaatgggtc ttgctttcta 109381 tccccctaac tgtttttctg tcctcctaac tgtttttctg ttatggcctg acttttatta 109441 tgagactaat tcagaatcag attaatcaaa tgcatgttaa atttgagtgg taggtttgtg 109501 gggagagagg gaagatgggc cagaaaacct taaaccagtg agcagttatt ttgcacagct 109561 ttggaagtac tttttttttt tttttttcat caggagagat aagagagaat ggagagaaat 109621 ggagagaatt gcagataaag ttgttttttg tttacttctc tcatgatgta agtcccaggg 109681 gacatgtacg aaagacaata cagtggtcaa gagcttgtgc tttgtattca gagtcctgta 109741 atcaatccca tctcctgtgt ttattttctg tgtggccttg gacatgttac ttaattcatg 109801 tgtgcctcaa tgtaaccatc tgcaaaattg agataatact agtcaccttt cttatgaggt 109861 tgttgtagag attaattggg aagctatttt taaagcattt ttatagtaat ttatgtaata 109921 agagctcaac aagttagcca tcatcatcat tgtcatctca tctagaaatc cttgatttcc 109981 atctcttttc tatcagctgc attatatctt gcccaagatc cttctgtagt ttgactatag 110041 agcatatgta attatttctt agtgttattg agtctgagtg gataaaagga ggatgtaaca 110101 gaaagctcca atatcctgtt tatcatctgg cagactttgg aagggtaaat gttctttaga 110161 cttacttttc ggcccagttg ataacacatt tgccccagca gcttattcct caggtaaatg 110221 aaatcttgct aaaaatacaa agttgacagt gaaacgcttc tggaagcact ggggtttgtt 110281 ttccggtgac agacaaacag caggatgtgt gtatcccact gctgtgctct attcaccttg 110341 catctctcag gcaggatttg gtattgactt ttctcagcta caggaaaggt ttacagaact 110401 ggtcttcatg aaatcagtta ggagtgttat taatgggtta ctgtcaaatt tattattgct 110461 gaaattttgg ctctttataa tagatgaatc aattgttaaa gcaacattga aagatacttc 110521 cattttctcc tcaaaggttc attgttccca gtgttcctct tcataagctc tgtgtggtta 110581 gtgacccata tatgattctc tgaaaatgtt aagagcttca aaagtcaatt ctatattgag 110641 tgatgcccta tattttcctg aacactttga tggagtttgc atctagattt attttataag 110701 aagaaaaaca ttaaactttt aaactttata acatcattct tgacatcaac cactaaatta 110761 ttatccaagc actaataata catttatatt ttattaaaaa gatggctatt gtagatttgg 110821 agatgtatgt tgtatttata tagccatctg tttcggagta agaagatagt acacaatttt 110881 atttctcctt tagggaagga atttaaaaat atttataatc tttattttta aacgctgttc 110941 atatggttac tgggggaaag aattcagatc ctaaaggatc agtcatatct ccagtagtgt 111001 tttctcttca gttttcatgt tttaatgtta ttgcaccttc tggatgctgt attttacatg 111061 agggacagaa tagtgagcta cagatatttg aaaggtgtag acatgaagga agaactggcc 111121 tggtttagta caaagaagcc aggggtggtt tagtgaaact caaaagtgaa aacaaacaga 111181 attcagaagg cacttgagac tgtcttttgc acggcctttg agacaagtga gcttctgcag 111241 tccctgtgat gtttaaaaat acccctcaaa cattaagcat atgtgtgtat aggtagaaag 111301 cgtcctggac catattattg atttcaagtc tatgaatctg agatcagcct cttgtgttta 111361 ttagtggtta gtgcttctga catggtagac atttttagtt tttaaatcag agtagttaac 111421 agtcagtccc cttcgccagc ttagttcata ctgctatatg ttgtggagtc ctttggaaat 111481 acactctgtt ttcccctttt caggtagaac ccaaggcaaa acctaaaaaa gaaaagctat 111541 atttaaacct gtaaatcctg tgggagaggg agaaaaagtt tttatttgca ggaatagacc 111601 tttttttttt tttttttttc tagagtaaga gttttaaggg aatagtgtct tgatgaagaa 111661 actaattagc catgcagtgt gagccactgt gtagcttgat ttttctattt tgtagagaat 111721 aggtattcca tttccccagt gcagctatgg gaattttgta gattggaaaa cgctgtgttt 111781 tgtagaatct caaaacaaag tcacccgctt gctctgcttg gagcttctca tctcttgtgt 111841 cccatttctg agccctttgg ctataaatgt tttgttgagg ggtgggggga atatagatat 111901 caattttaat atttcacctc ttaacacgta ccatttggtc gtatgatatg aattctgcac 111961 tcctgactct gtcttttttc catgatggca ttttaaccag catataattg tggatgtcaa 112021 ctggaagtca gaaaatgtac ataccttctt ctttctcttg ttgacctttt tgggatattt 112081 aatgttttta gtggaaacag tgtctgaaag acatctcatc tggcttttca cataatcaga 112141 gtaggattta actggagtgg gaaatgttca gttatgccat ttgggccaaa gactcccctc 112201 acacccacac caaaggagga cctgttttag gatacatggt actcttcaca aatttaagtt 112261 ccttttcaaa tttcttttct agatcctgag gtgacttcct tctaagtttt tcctccaaag 112321 ctaccaaata aaccctagta agtagtaagc aaagcaagat tctgaattca attctactta 112381 ggataatttt gtagtaattg tttttataga tatgatggct agcagcaaaa caatgttcct 112441 atattagaga cacatacatc tataaatttc tatgcaggaa gtaatgtcat atatgctgct 112501 ataacccatg tatattcttt cttctctact catcactcat tccaattcca tggttgttta 112561 aattcataaa catattggat gtatattatt gcacatttta tttcagagct gaaaatatat 112621 tgagttatct gataactacc gtgaactttt gagataagtt tgagtaaaat atgttaccga 112681 aggagtagta aaatttttat cactcattgt acacagagac tgaaacaaat tttccctcta 112741 aatttgccct ctctacaatc acaatctctt attggaccat aacagcagaa tatatcatta 112801 catggtttag tgcaccatgt ctcaaatttc aaggtgcaca caaatcaccc agggaYcttg 112861 ttaaaattca gattctgact tggtagaact gcagtgggtc tgagatccca gtgattcccg 112921 tgctgccagt ctgcaagcag caaggggtta acttttccag atgaaattct ggtcacaatg 112981 ctaactacat tctgaaaaac ttatacagac aactaacaat agggctggtt gttagtaatt 113041 ctacccttgc tatgagtgct cattaaaacc ttacgttaaa^'* tttatcatta tgatttggac 113101 aaaatgaaga agtataggca tcaaaatgaa gaagtataga agtcaggaag tataggcatc 113161 tacctatatg agcctataaa caaaactgta tctcatctga aatgtgtaat tatcacagaa 113221 gagaaagtga ctaaataaaa ttattttaac aacatatacc aaagcttaag cttctggaaa 113281 gactacctaa tattccataa tagaattagc aaaacagtta tcaagcctat tgatggcaag 113341 cattgaagtc cagtaaggga tgtaacaaaa ctacagtcac tgaagcagcg taaaggtcac 113401 tgaagcagca taaaggaatg tggtgtcctc aagagtcctc cattcagcag tgtccactag 113461 ctgaggaatt caggatttaa gtgaaattgg gtcagatgcc aaagaaacca tgtagtagaa 113521 aaataagcat tttaaaacta aatcgcaatg ttagacattg aattctgatg aatggaaaca 113581 tctggtgaag tgttttcatg actggaaaat atctcaactc agaaggtacc ttgtttttaa 113641 tgtagtttct caggactaat ttttttagtg gcctattttt agttaaaggg gaaagcttat 113701 aattagtaaa acaatccatc attgagtaaa tattaacaga actatttcat gcccggtctt 113761 ttgtgctttg ggaacactaa agaaatagaa gatatggttt gtgtgctcaa ggtgtttaca 113821 ctctggtcat ggaaatacaa acacgtgaga aacagtgctc agcaaagacg gagctccccc 113881 caccccacca aaataaacca aacacttgaa aacaaattct acagtagctt atataagaat 113941 atataataac atatatttca gtaacaaatt ataaaataca atctaaaaat gatgtagttg 114001 gtagtgaggg catttttggt tgtgacagtg acaatgatat aagggcagga ctagcattta 114061 gtacacagaa ccatggttgc cagatgctct acaacgtgta ctgctgtgga aatgctgcac 114121 ccaaataatt ttcagccaaa atgcccagga tgccaccact gagaaacagt gccaggatgt 114181 cagagttaag gaaaatctga aaagactgga gacattaaga gaagtgtata catggtatgt 114241 acctgtcttt gtcctttcta aatcctaaaa ttctaaggga aagtggaaca caaaggaagc 114301 acaaagaagt gaatttatgt gtgagacttt actagttgac ctatctaaaa ttatttacca 114361 gctgcaaact gctgcctaaa gttcatagta gaacattaga gctaaaacag atctgtatca 114421 ttttacagat gagaagactg agatctgggg aatttaagtg gcttgtcttg aggcacttag 114481 ttctgacttc tatgggcagt atgtttgcat gtatattaga taatgttctg aaggtgactt 114541 taggcaagat cttggttctc ataaaacaaa gctgtaagta aaaaacacat tcttgcatat 114601 atccttctat atgtgtacat atctttgctc tgtgtagcca ctcttactgc catctctgtg 114661 tatacacaca tacatacaca cgcatactat tagggagaaa atagagaaga cagcaagcaa 114721 agagaggaaa gcatactttt agatttgaca gatttaagtt atagatgaag gcagttatca 114781 ttggttatga ttctagtggc aatgattcta attcttccta cctctctctt ctacccaaaa 114841 ctcttgcaca tctatcctta atagctgaaa ttacttttat aagggagaaa acttgttgtt 114901 ctgtaacgct taaagttcag ataattctgg gagaggtagt actacgattt aagtgctcaa 114961 aaacttataa atgactgatg atttttttat attgggagca gattttgagt aggataaagc 115021 catcaggcςc tcctggggta ttggacaaag ggaaaaaaac aaatgaaaga ggttgtcaag 115081 atttttgctt atttcatagt tttgcattgg acctgtgatg gatattcctt tcatgaatat 115141 caaaagagca tgacctagct acagcctgac gcatgataca tatttgctgt gggttaacct 115201 ggagtctttt aaaccaattc ttttccagtg tctgccttca actaacagtg tggagtgaag 115261 tagtagagaa aatcagactc tgaacccagt aaaatgctga tcaccagaaa atgggtgatt 115321 caaagggaca attttcagac cgaatgaatt cacttgaaat gaatgccaac cttaactgaa 115381 ttaagctgtg ctctttcaaa tccactgctg tgagttcagt agacagttgt ctggatttta 115441 catagctcta agctagaatc gtaggtcaaa ttgtgacttt tggagcctca tacactgttt 115501 gaatttctaa caatttttac tcaggtttga gtttgccagc aaatgaacaa gttcctgtta 115561 ataatgagta gaccaaatta atcgcttcag atgaatatcc atatgtgtgg gtgcatctca 115621 aagcaagttt gaaattctag cttctattga atttactgga aaaaaaagtt tattttggta 115681 tttgtgatga tttcttcttt ttatatgttt tcgaatacca ggagacatcc ctgcttatgt 115741 gatttttgtt acttcagttt ctaaatggaa caagtagtat gaaaaagtac agtcatggag 115801 aagactattc ttagttctca ttgatattag aatttctgtc ttgttttcac acgatactga 115861 tagcatagct gtctactgga atttgccttg ggcagaggtg ccaaagatat tttcttctgg 115921 acccatgatt tgggaaaacc atttttaacc tgtggaagtt ccttattttc cacgagttaa 115981 tgaacaaatc tttactggac tcttcaagag gagattcgaa gggaaaagta ctttaggggg 116041 ctataaaatg aatataagac agtccttgcc ctgtggaaga gataatcagg ttgttgacat 116101 taaagtatca caaaaagaat aattacagtc taaggtatgc aaaatattgg agcagactaa 116161 attcactgaa gtgaattctt aataaaggat tggtccgagt gggtgggatt taatcaacaa 116221 gtgcatctag gcaaaggcaa ttttggagac aagtcatggc ttggtgggag gaaggttttc 116281 aggctgaggg cggtaagaaa gcatgtgtga aggacagtga agctgacgga cagtgcgtag 116341 aatgtctgag ggtctcctgt atccagaatg ttcacagctc atggcctttg tatttggcca 116401 agtgcccaca tctttaagaa tgtatgtagc taagaaatgt aattttgaaa accaatttgt 116461 ttctatttaa gcattgttta ctgacctaat taaattccct taatgtcata tactaattta 116521 gtgtgactga ttattttgac atattctaga tacttttaaa caaagaagac atatgtaaat 116581 gtaatgattg caaattatta atatattact atacttatta acagtgtggg tttatgtaat 116641 cttattatta tttctctatt cttttttata cctttctagg gttatagatc tacttattta 116701 gatttcttcc agggagttca gtaataatat tttttgtgtc tttttgggat tttgtaatct 116761 ttacaggacc acaagtaaaa gaattccttc tcagaacagc cacggttaca ggatctgagt 116821 tattgactgt tggggtcctg gatgcttttt tcaagtcaga gattcacatc tgagtcacgg 116881 gttggcagtt aagctgagtt ttctttttaa gggttaaatt tcatatgtat tattaaaatt 116941 taacttcttt aaaaaaatgc tttccacact ggttcacata ggttttcttt ttaatcttgt 117001 ttatctccac cagatgtgta ctttgtaata cgttgcttag gcaacatcac ctgcccttta 117061 gcctgttgca ttacatccac ccacctggtc tgctgccatt ggaacatgct gtgttgcttt 117121 tctttctaca ctcatgctgc ttggaccctc cccacaggcc ctgatcattc attcctgtcc 117181 ttgatacagt tccttggtac tttttttcta gcacttcttg gcttactcac agttctgtat 117241 cttaaaatca accatattgt attatattca tacttctttt atattatagc tgccatttgg 117301 cctttatagt aacttttctc ttttgaaatc ataatgaact catggtcttt cagcaactca 117361 tcttgttcta tttaaccata cttttatttt tccttttgat gctcgaataa ataatcacag 117421 tttgatcgtt gggagctcct ttaggcagat tcctttgtcc ttctagcacg atccctgaca 117481 tttttgaaag gatgccagtt ttctggtaac agctggatgt ttcctggctc tttcacactt 117541 cctgcactgt gaactggaat ctattacttt ccaaagattt cttcctttcc ttactggaga 117601 actggaacat aggccaaaat ctgggcacta ggggtgcaca tgaaagttag tagtggataa 117661 aagggctact gtttggtggt tggaagagtc tgtgtttttg aggtttgggt tctcagtgat 117721 tttttccaat ttgacattcc gtacttctgt ctctgagttt ttttaatata tgaggtttta 117781 tcttttacta agacctttta ctgcactgac cataagcatt ttgctgtggg cagaaagatt 117841 ctatttgggg tgggaagcat ttattcagat tgctgacaag ttaatataag cattcaactg 117901 aagacttgta cgcaggggag tagcgccagt gtatactgcg tcctccagag ccctctttca 117961 ttgctaagac ccaggctgct cgcttttctc ttcatgcact ctggatactt aaatttattc 118021 taagagctct cctaccctcc ccttttctcc cctcttaccc ctcttctccc ttctcccctc 118081 ttacccctct tccccctttt ccattttctc tttcccttcc cccacccttt cccctttccc 118141 ttttcccttt ttgagatagg gtctcactat gttgcccagg ctggagtaca tggagcatag 118201 tggcacagac tctgcagctc actgcagctt tgccctccct ggctcaagag atctgtccac 118261 ctcagcctcc tgagtaggtg ggactacagg tgtgcaccac cacacccgcc taatttttat 118321 atttgttttg tagagacagg gtttttccac gttgcccagg ttggtctcga actcctgagc 118381 tcaaatgatc cacctgccac agcttcccaa atgctgggac tacaggtgtg tatcaccatg 118441 cccagctaag ttgattgttt tctactttta ttttgtagtt tgctagtagt tagcaaaaat 118501 ggtaaacgtg aaatgtttaa gaatatttat gggaaatatt ttaagttgag aaccttgtta 118561 aatttttttt ttctcaaaaa ttagggaaag gcggccctct tctgtcttaa tgatagaata 118621 ctttagagat gttggttttt cacaggtgca tagtttccac tgatttttat aattatcaac 118681 tgtgccatag tcagatccat taaatgagag actacctgac tcaaagtatg tattgtaagg 118741 ccgttaaggc atgaagatgg agagaaagct gtactttgca gtagattctg taacagtttc 118801 tcttgcttaa attgtatagg ttcagaaagc catcagaatt tctaattgga gttcctctgt 118861 ttcctgaagc caacaaatga ctttttttgc tttattgtat tttctagaac ttaaaataca 118921 atgttaaatc aaagtgtttg tgaaagtgga tgtccttgaa ttttccctgt ttttaggtga 118981 aaagcatgta gtttctcagc attaagtatg atgttacatg taattttttg gtagatgctc 119041 tctatcagtt tgaggaagtt ttactctgtt tttagttggt tgagaggttt tattgtgaat 119101 ggatgctgaa tttatcaaat gcttttttct gagtctattg agatgatcat atgattttta 119161 aaaaactgtg tattaattgc ttcataacaa attatcccat aacttaacat cttaaaacaa 119221 catacatttt taaaaaatct tagttcctat gggtctcttg cagatgctcc ttagctggct 119281 cagggtctct tatgagagtc cagtcaagca ggaagctgga actgtggttg tccctgaaaa 119341 cttgactcac aaggttgttt gcaggcccta gtctttctgc acaggtgcct ctccacaggg 119401 ctgcctcatg gcatggcagc cggctttccc caggtctggt gatctaagag gggatactca 119461 aggcagagag agcaccaaaa tagaagaaac attgttctta caatgttttc tcagaagcgg 119521 tatcctatga tttttgccat attatattta tgggatacaa gtcaacaaat gcagcccaca 119581 ctcaagagct ggggattaca taagagtgtg aatacttaga agtgggtgtt attgggagcc 119641 atgttagaga ctgcctacca ctgtatttta aaatggtgaa ttacagattt gtgaatgtta 119701 agccaacctt gcattcgtgg gattagtgtg acattgtcat ggtttactat cttctttata 119761 tattgttgca ttcaatttgt tgaagatgta ccagtaattt tttgcatctg tgttcatgag 119821 agagattgat ctgtagtttc cttacaatgt tcttgtgtgg ctttggtatt ggaatgacac 119881 tggccttata aaatgaattg ggaagtatat cctcttcatc agtattttga aagggtttct 119941 gtacaattga agtcatttct tcctttaatg tttgttttaa cttcaccagt ggtgccacct 120001 ggccctggca ttatctttgt ggtaatgttt ttgaccacaa attcaattcc tgtcatagac 120061 acaggcctat tcatgttatc tatttttttt tttaactgag tgagctttgg tagtttttgt 120121 ctttcaaata attggtttca tctaagttgt ggaatttatt ggcacaatgt tgtttgtagt 120181 atttgtagaa catctgtagt gatatcactg ctcccattcc tgatagtaat attggcgatg 120241 tatattttct actttttttt ccccttatct gtctggctag atgttcatca tttaaaaaaa 120301 acttctctga aaaccagctt ttggttttat tgatttttct ttattgtttt ctgttttcta 120361 ttttatttat atccactttc ttatttatta tttcactctt cttatcttgg tttttatttg 120421 ctttatttat ttattttttt tttagtattt taaggtggaa gctgaggtta ttgctttgag 120481 acttttcttc ttttctctag tcatttagtg ttacaaattt tcctacagct aaagtactac 120541 tttagctgaa tctcaccatt ttcgtatttt gtgttttcat ttttatttag tccaagatgc 120601 tttctaattg cctttctcta ttaatttagt catcaactat tttctgtcat ccttatcttt 120661 tagtttctat tttaagtaat ttgatttcaa cgtgccctta catttttttt tctttcaaat 120721 tttctgtgtt tgcagttcat tgacttctca ggcccatgta tttataattt aattgcttta 120781 gtgatgtggg tggtttctta tttactgcct tcatgtcctt aagaagagca caaaaaccct 120841 taaaaatatt gcatgctcca acatacttgt aatWcatttt tactttttga tcatgactag 120901 aggactctgc cttgagtctt ttaaaaatat cttcagctgt tttctcacat gctaaaaagt 120961 atgataatat ttttctcatt tgacttagtt agaattcagc ctgtgcttag tagttgagac 121021 atactcatag ggttgatgtt taatgattaa aaactttttg tttcaaaaac ttgaaatggc 121081 ttattttaat tatacatgct tttctacttt agtggttttt aaaacattac atatgttgga 121141 atatttatta taaaattcac acaagagtgt accaaaaatt gctaatcttg cccgttcaat 121201 tccacatgtc tggagatatc tgatgttaat agtttggtgg tgtgttttcc tgtatacttt 121261 tcaccatgct catacactca caaatatcta tatctatgca tctgtgtctg tatttatatc 121321 tgtatctgtc tatatctatc catatacata gccgcattta taccccacat ggagtcattc 121381 tatacatatt agctctgtgt atctgtgggt tctgtatgca catactcaac caaccacgga 121441 cccaaagtgt gtattcaaaa acttcgtatt tttaccttaa cagtgtgggc ttttcataaa 121501 tatcttcggt ttttctgctt ttgatagcat atagggatgt gggaactttt tataagaaga 121561 aaagcattct aaaaacaatt ttatttagag ttatattttc tttagagaga acaattaaat 121621 tagttagctt tacagacaag ccagaggcca tcaaattatt gaataaagac aacaaagtct 121681 ccagagtatc gggagaatga caggcttaga actaaagtaa aaagcaagga gcaaaaatca 121741 cagagactga aataaaatga gagggtgggg aaggctgggt gagaagagaa tgggtgaaga 121801 aggaagaaga agggaaggag gtggaggtct agtggaataa tgtaaaccaa attttgaaat 121861 gaatgctttt tggtgttttt cttttacaat gttatttctt tttatccatt agctttgaaa 121921 taaaggaaac ccccaccatt gtcctcagtt cttcagtatc tctaaccatt agctccattc 121981 attccaattt ggagatgaaa tcaagatggg gacagatttt aagcatacat attcatgcat 122041 aaaactttta aacaacataa tgccctttcc ttctctagcc taggttagct gcttacacga 122101 tgacccatca gttaatgtcc atctgatttg cctatttttt gttttttaaa ttaaggctag 122161 ttacccaacc tcttaatgat tcagaaataa accacttcca gtcagatggt aaaacgtgtg 122221 acagagttca agaatcatgt tagggtacta ctagcagcct gggccttaag tttctcattt 122281 tagaggtaga ttttttagtg taagctctag tgtgagatct aagtgtaaac acaatgattg 122341 tgaggatttt tttgtactgt aatttatgct gatgcagctt ttagaatgtg ggctttttgg 122401 gtatttcctg aaactgaaat tggcatgctt tctagagtta tatattggca tgtttagtga 122461 tattaaagtt gbagtgaaga gttctgaatt taatttcttc ttttctcaga tatgtgtcac 122521 aaagatgtct acacggaact gccagggaat ggactcagtg atcaaacccc tggacacaat 122581 tcctgaggat aaaaaagtca gagttcagag gacacagagc acttttgacc catttgagaa 122641 accagctaat caagtaaaga gggtgcattc tgagaacaat gcttgcatta actttaagac 122701 ctcctccact ggcaaagagt cacctaaagt taggcggcac tccagcccca gctcggtaag 122761 tgcagtcttt ttgtttatca ctgggtaaac agaaggaata gccYtcttat gatagcatgc 122821 ggtgctggaa gacagcagga aactttatca gtgccttatt atgcattctc tcccagggtg 122881 gttgaatgtt ttggaagaga gagagcaaac tatatatgga ctccttattt ataagcacta 122941 agcaagcaaa tgaatgaaat gattcaactt atttttggaa aaatcatttt tcccccttaa 123001 ttgtttctag ttagaggaat ttataattaa aagtcttttg tatttcaaac ccttggagag 123061 gttattgaac tttactgtgt aggcagtaag gatagttttg aaattagcaa attcacaagg 123121 aatttcattg cagaataaat atcaaaattt gttcacttgc gttaatccag ttttttttgg 123181 gggggtactc caccagtctt tctcatgtga ctctgtaaag tgacaagttg aagttctttt 123241 ccaggacaaa gccctgtact gaatggaaaa tgctggagta gaaatctgtg tagggtagat 123301 tcagtaggac caaaggaaag aagagaatgt ccagaaagaa gtgttagagg gaaacagact 123361 ttagatataa ctagtgattt acaagttaga aaggaacaca ccaagagaga atattctctg 123421 ttatatttct attctcaaat acattttttc ctactttttg gcttaaatta atatacatta 123481 tttacaattg tatgataatg taaattttgg tcagggaaac cacaagtatg ctatgaataa 123541 atttccttcc ttgcacaact tcttcatttt cttagttgtc attgtctact tttccttcat 123601 tcaaattaag ataattttaa acacaatttg aggcctgcaa ctatatgaca aaactgtaaa 123661 atgcctccaa aacaaatcag ataatctatc agtttttctc ccccactgag attgccctgg 123721 cagttcttca tagtcctaat ttaatataga ttggttaacc tctaatccta tagtcataag 123781 gcgtcctttt ctgagaattt tttcctcctt ttttaatgtt aaatacccat tctctgggtt 123841 acatgtcttt cttgttcttg gtttatttca ttgttttaaa gtacatcctc gcagtagctt 123901 cttgagaaag ggtgatgggg ggtttgtcat atgactatga ttttatctgt cgttgattac 123961 ttgattaata atctggccaa gtatgtgatt ttagtttaga aaataatttt ttcttagact 124021 tttgaatacc ttgttttatt gttttctagg tgcctagatt gtattgaaat ccctagacta 124081 ttctggtttc ccagttcatc ctttatctgc tttttttgtt tgtggaactt tctaggactt 124141 tcttttcatc cctggtgtca tcctttttct tggtatcaat gggtgttttc aatttttgag 124201 ttaatttctt tcagtttcaa aaattttctt atatgtttat ttaatttttt gtaatcttct 124261 cttttacgat aacattttta ttagttggat gttggcatta ttggattgat cttctagtta 124321 ccttttcttt tccctattat tttaaatctt ttttttccta ccttctgggt ttttttaact 124381 tttaattttt aacccttcaa ttggattttt aattatacta atatttattt ccatgaactc 124441 tttcttattc tttgaatgct cttttaaaaa gtatcctgtt ctatttcaat gaataacata 124501 tcacttcata tgtttctgag gatacaaaat gtagcttggg gaattttttt tccttttaca 124561 tattctctga attatttctg gatttccttt gagtttcttg tttctgttta tttgttttgg 124621 tctctgcctt acctgttgag atttttggtg ggtctatgtc atgcctcttg gagagaaact 124681 gttggctgtc agtttatgtt atgagtaatg tactcagaag ttgattggaa gctctgtgcc 124741 tgggtggctt gtcagttggt tggcttcagc atagggactc ttggtgaaga cctagtcgtt 124801 ttatttaagt actctcaaat gtcgctgtct cttgatcttg tttttgttac tgggtgtttc 124861 tcacaaaatg gacttaccca atttattttt tttaggacat ataaacctag ctgtcactat 124921 tctgagatga tcaagaaggg actgaggacc cttcagttct ctatgccaac tttctcatga 124981 tttttttttt tttcattcgg tatgactctt caatctgata tccactctgc ctggtatcca 125041 agccccagtt gaattctctg attcaacctc ttcagagaat aaatctctgg cgggactagg 125101 aagggatagg gggctggccg agggagactg gggcaaagac ctccacctta aattcactcc 125161 aactaatcat atcatttgia gccccaactt gaacttcagc ttccagtttg tgagtatttt 125221 tgggattctg aagtatgaat tgacttattt cttactggct tatgccttgg atcatgtagg 125281 tatcaaggtt tttttttttt tttttttttt tttttcccca ctcatcctag gcaatgtgac 125341 ttctcaacca tttgtgtcct gtctttacat ttttatttct atctcgtctc tagtgttctc 125401 tttactcatt ttgattgccc ttatgggttt taattttagt attgttttag tatgaattgg 125461 taagggggag agataaatac atgttttcaa gccatcaagt ttcactggaa gttttcacag 125521 tttctctatt gtatttttta gtttctttag atcatcttgg gcttaccctt tcctggttca 125581 ccctgggatg acttttttta atatatatta ggtcatttat attactttgt gtgggaactg 125641 ctttgctttc tttttatttt aggaattttt gcttcaattc aatgtgccct ggaaaaatgt 125701 cttttctctt accttatcaa actggaaatg gcttcgtttt ctctttcagc aggatgctat 125761 aatatcctgt ttttttctga gtcctttctg tttgctgccc ttttaaaaaa tatatttttt 125821 ctttttttaa aattatactt taagttctgg ggtacatgtg cagaacatgc aggtttgtta 125881 cataggtata cacttgccat ggtggattgc tgcactcgtc aacctgtcat ttacattaga 125941 tatttctcct aatgctatcc ctcccctagc cctggtgtat gatgttcccc tccctgtgtc 126001 catgtgttct cattgtttaa ctcccactta tgagtgagaa catgtggtgt ttggttttct 126061 gttcttctct tagtttgctg agaatgatgg tttccagctt catccatgtc cgcgcagagg 126121 acatgaactc atcctttttt atggctgcat agtattccat ggtgtatatg tgccacattt 126181 tcttaattca gtctatcttt gatgggcatt tgggttggtt tcaagtcttt gctattgtga 126241 actatgctgc agtaaacata cgtgtgcatg tgtctttata gcagaatgat ttacaatcct 126301 ttgggtatat acccagtaat gggattgctg ggtcaaatgg tgtttctagt tctagatcct 126361 tgaggaattg ccacactgtc ttccacgatg attgaactaa tttacactcc caccaatagt 126421 gtaaaagcat tcctatttct tcacagcctt tccagcatct gttgtttcct gatgtttcaa 126481 tgatcatcat tctaactggc gtgagatggt atctcattgt ggttttgatt tgcatttctc 126541 tactgaccag tgatgatgag ctttttttca tgtttgttgg ctgcataaat gtcttctttt 126601 gagaattgtc tgttcatatt ctttgcctac tttttgatgt tgttttcttt tttctcttgt 126661 aaatttgttt aagttctttg tagattctgg atattagccc tttgtcagat ggatagatta 126721 taaaaatttt ctcccattct ggagtttgcc tgttcactct gatgatagtt tcttttgctg 126781 tgcaggagct ctttcgttta attagatccc atttgtcaat tttggctttt gttgccattg 126841 cttttggtgt tttagtcatg aagtctttgc ccatgcctgt gtcctgaatg gtattgccaa 126901 cgttttcttc tagggttttt atggttttag gtcttacatt taagtctata acccatcttg 126961 agttaatttt gtataaggtg taagcaaggg atccagtttt ggctttttac atatggctag 127021 ccagttttcc caacactatt tattaaatag ggaacccttt tcctattgct ttgtttttgt 127081 caggtttgtc agagatcaga tggttgtaga tgtgtggtgt tatttctcag gtctctgttc 127141 tgttcattgg tctatatatc tgtttttgta ccagtaccat gctgtttttg ttactgtagc 127201 cttgtagtat agtttgaagt caggtagtgt gatgcctcca gctttgttct ttttgtttag 127261 gattgtcttg gctatgcagg ctccatatga aatttaaagt agttttttcc agttctgtga 127321 agaaagtcaa tgatagcttg atggggatag cattgaatct ataaattact ttaggcagta 127381 tggccatttt catgatattg attcttcata tccatgacca tggaatgttt ttccatttgt 127441 ttttgtcctc ttatttcttt cagcagtggt ttgtagttct tcttgaagag gtccttcata 127501 tcccttgtaa gttggattcc taggtatttt attctctttg tagcaattgt gaatgggagt 127561 tcactcatga tttggctgtc tgtttgtctg ttattggtgt ataggaatgc ttgtgatttt 127621 tgcacattga ttttttatcc tgagactttg ttgaagttgc ttatcagctt aaggagattt 127681 tgggctgaga tgatggggtt ttctaaatat acaatcatgt ctctgcaaac agaggcaatt 127741 tgacttcctg ttttcctaat tgaatacact ttatttcttt ctcttgcctg attgccctgg 127801 ccagaacttc caatactatg ttgaatagga ggggtgagag agggcatcct tgtcttgtgc 127861 cggttttcaa agggaatgct tccagttttt gcttattcag tatgatactg gttgtgggtt 127921 tatcataaat agctcttatt attttgagaa acatcccatc aatacctagt ttcttgagag 127981 tttttagcat gaggggctgt tgaattttgt caaaggccct ttctgcatct tttgagataa 128041 tcatgtggtt tttgtccttg gttccgttta tgtgatggat tacatttatt gattggctta 128101 tgttcaacca accttgcatt ccagggatga agccgacttg atcatggtgg ataagctttt 128161 tgatgggctg ctggatttgg tttgccagta ttttattgag aattttctca tccatgttca 128221 tcagggatat tggcttgaaa ttttcttttt ttgttgtgtc tctgccaggc tttgctatca 128281 ggatgatgct ggcatcataa aatgagttag ggaggattcc ctctttttct gttgtttgga 128341 atcgtttcag aaggaatggt accagctccc ctttgtacct ctggtagaat tcggctgtga 128401 atccttctgg tcctggactt tttttggttg gtaggctatt aattactgcc tcaatttcag 128461 aacttgttac tggtctattc agggattcta cttcttcctg gtttagtttt aggagggtgt 128521 atgtgtccag gaatttatcc atttcttcta gattttttag tttatttgca tagaggtatt 128581 tatagtattt tctgatagta gtttgtattt ctgtgggatt ggtgttgata tccccctaat 128641 cattttttac tgtgtctatt tgattcttct ctcttttctt ctttattaat ctggctagag 128701 gtctatctat tttgttgatc tttcaaaaaa ccagctcctg tattcagtga tgttttgaag 128761 agtttttcct gtctctatat ccttcagttc tgctctcatc ttagttattt cttgtcttct 128821 gctagctttt gaatgtattt gctcttcctt ctctagttct tttaattttg atgttagggt 128881 gtcaatttta gatctttcct gctttctctt gtgggcattt agtgctataa atttccctct 128941 acacactgct ttaaatgtgt cctggagatt ctggtatgtt gtgtctttgt tctcgttggt 129001 ttcaaagaac atctttattt ctgccttaat ttcgttattt acccagtagt cattcgggag 129061 caggttgttc cgtttccatg tacttatgtg gttttgagtg agtttcttaa tcctgagttc 129121 taatttgatt gcactgtggt ctgagagact attatgattt ccattctttt gcatttgctg 129181 aggagtgttt tacttccagt tatgtggtca attttagtgt atgtgtgatg tggtgctgag 129241 aggaatgtat attctgttga tttggggtgg agagttctgt agatatcatt taggtctgtt 129301 tggtccagag ctgagttcaa gtcctagata tttttgttaa ttttctgtct aattgatctg 129361 tctgatatta aagtttccta ctattgtttg ggagtctaag tctctttgta ggtctctaag 129421 aactcgcttt atgaatcagg gtgctcctgt attgggtgca tatatattta ggatagttac 129481 ctcttcttgt tgcattgatc cctttaccat tagtaatgtc cttctttgtt tctttttaac 129541 tttgttggtt taaagcctgt tttatcgagt gcaacccttg cttttgttgc tttccgtttg 129601 gttggtaaat attcctccat ccctttattt tgagtgtatg tgtgtctttg cacatgagat 129661 gggtctcctt aatacagcac actgatgggt cttgactctg tccaatttgc cagtctgtgt 129721 cttttaattg gggcatttga cctatttaca ttttaggtta ttgtattgtt aggtgtgaat 129781 tcgatcgtgt tattatgatg ctagctggtt attttgccca ttagttgatg cagtttcttc 129841 atagcgttga tggtctttac aatttggtat gtttttactg tggctggtac tggttgttcc 129901 tttccatgtt tagtgcttcc ttcaggagct cttgtaaggc aggcctggtg gtgacagtgt 129961 ctctcagcat ttgcttgtct ctaaaggatt ttatttctcc ttcccttatg aagcttagtt 130021 tagctggata tgaaattctg ggttgaaaat actttccttc gagaatgttg aatattggcc 130081 tccactctct tctggcttgt agggtttctg ctgagagatc tgcttttagt ctgatgggct 130141 tctctttgtg ggtaacctga gtcttctctc tggctgccct tagcattttt tccttcattt 130201 cagccttggt gactctgagg attatgtgtc ttggggttgc tcttcttgag gagtatcttt 130261 gtggtggtct ctgtatttcc tgaatttgaa tgttgtcctg ccttgctagg ttggggaagt 130321 tctcctggat gatatcctga agagtgtttt ccaacttggt tctattctcc ccgtcacttt 130381 caggtacatc agtcaaatat agattttgtc ttttctcaca gtcccgtatt tcttggaggc 130441 tttatttgct tcttttcact cttttttctc taatcttatc.ttcttgtttt atttcattga 130501 gttgatcttc aatctctgat gtcctttctt ccccttgatc gattcagcta ttgatacttg 130561 tgtatggttc acaaagttct tgtgctatgt ttgtcagctc cattagttca tttatattct 130621 tctccaaact ggttattcta gttagcagtt catctaacct tttttcaagg ttcttagctt 130681 tattgcattg ggttaaaaca cgctccttta gctcagagga gtttgttatt acccactttc 130741 tgaagcctac ctctgtcaat tcgtcaaact cattctccgt ctggttttgt tcccctgctg 130801 gcgaggagtt gtgatccttt gggagagaag aggtgttctg gtttttgtaa ttttcagcct 130861 ttttgcgctg gtttctcccc atcttcatgg atttacctac ctttggtctt tgatgttggt 130921 gaccttcgga tggggtctct gagtggacat cctttttgtt gatgttgatg ctgttccttt 130981 ctgtttgtta gttttctttc taacaggcgc ttctgctgca ggtctgctgg agtttgctgg 131041 aggtccagtc tagaccctgt ttgcctgggt atcacgagca gaggctgcac aacagcaaag 131101 attgctgcct gttccttcgt ctggaagctt catcccagag ggtcacccac cagatgccag 131161 ccagaattat cctgtatgag tttccgtcgg tccccactga gaggtgtctc ccagtcagga 131221 tacatggggt tcagggaccc acttgaggag gcagtctgtc ccttatcagg gcttgaacac 131281 tgtgctggga gatccgctgc tctctttaga gctgtcaggc agggatgttt aagttctgct 131341 gaagctgcgc ccacagccgc ccctttcccc cgttgctctg tcccagggag atgggggttt 131401 tatctctaag tccctgactt ggggctgctg cctttctttc agaaatgccc tgcccagaga 131461 ggaggaatct agagaaggag tctggccacc agcggccttt ggcctggcct tgctgagcta 131521 cagtgggctc tgcccatttc aaccttcccg atggctttgt ttacactgtg agggtaaaac 131581 cacctactca agcctcagca aaggcgattc tcccaccccc acctagctta agcgtcccag 131641 gtcgacttca cactgctacg ctggcagcga gaatttcaag ccagtggatc ttagcttgct 131701 gggcaccgtg gaggtgggac ctgccgagcc agaccacttg gctccctggc ttcagccccc 131761 tttccagggg agtgaacggt tctgtctccc tggcattcca ggtgccactg gggtatgaaa 131821 aataaactgc tgcagctagc tcggtgtctg cccaaacggc tgcccagttt tgtgcttgaa 131881 acccaggccc tggtggccta ggcaccggcg ggaatctcct ggtcttccgg ttgcaaacac 131941 tgtggtaaaa gcacagtatc tgggccagag tgcactgttc ctcccggtac agtctctcat 132001 ggcttcactt ggctggggga gggaaatccc tttacccctt gcgcttcctg ggcaaggcga 132061 tgccctaccc agctttagcc ctccgtgggc tgcaccaact gtccaaccag tcccagtgag 132121 atgaaccggg tacctcagtt ggaagtgtag aaatcacctg ccttccgtgt tgatctcgct 132181 gggagctgca gatgggagct gttcctattt ggccatcttg ccagcaaatc ctgtctgctg 132241 cctttttgtt ctctcccctg ttgtgataag aaggggtact ttattatgtt tttgtttttt 132301 tttttttttt ttttttttgg tagaaaggtt aatttccact ggattctgaa ttgggcagaa 132361 aatggaaaca ttaacacttt ttgcataacg ccattttaca tcccctgcag cagtgtaaag 132421 atttgatcag ttaattccca tgggaagcat gggaaaacaa gggagcctta tagacacggg 132481 tgttattttt aacaatgctt agaggatgta acaatgactg ataagcatca aaggaagacc 132541 ctgtttcctt aagggtcacc atgatttatg tcatactttt attttatcat tatttctttt 132601 aaaatattag ttatctttta taggctccaa gagtagagct gaaaaggaag gaaaatgtga 132661 tagaagtgtg gcattgcagc cactgtttta atgaggaaag cattgttttt tggaaatact 132721 gtggtagaaa ctattttaaa atatcatgcc ttcccagccg tatacatcta tatgctcttc 132781 acatacaggc cattatatat taggagcctt gactgaaatc aaggaaccaa gaatgccttg 132841 acctcagtgg ccatcatgct aatgtaactg gctgattggt ttttttcttc agatagtggc 132901 actttaaaat tcacgcaaaa tataaagaat gaggttttat ttatagtggt atattttaag 132961 agggtgttta agaggttttt aaatttgttt cagatgtata ttgagtgccc acttttccta 133021 ggactagttc ctgtgtggtg tttaataccg tcactgatgt gacaaacctt ccctccccta 133081 ttcctgccac ctcctctaac ccagctgtgc tcctcagtag ctgcagttct tgggagtact 133141 acaggagatt tcctgtcttg ctggaccaat ttagaaggga tttcattgag ttatgctgtc 133201 ataagctgat cttaaagagg gcatattttc agaaactcat atttaggtta aggtcctctc 133261 tacattccac aaattgctcc aaatttacct cttttcatca ccataaaaat ctatatccca 133321 tgataggcag gcctaatctg ggagatgtgg gaggagggtg caaacctgca aatgagagtt 133381 tcacttctgt ttttagatac ttgttcttaa ggtgtggttg gtgtgtcatc ttggcgttac 133441 ttcctcttct ggggagtgga aaattcccag attagaacca agcccccttg acaggttgtt 133501 accatgtgtg gtgtttggat ccatacctct gcacagcacc tagatctatt ttataaccaa 133561 gttacctatc aatgatgcat taccttagtg tggctgtaat agggctatca atgctgggtg 133621 ataaagcttg ttctggagat caaaggcaaa ataaaaatta gcccagtcag gtttgacttt 133681 aaatccttat ttaatggagt cacgtggttc tgattgaatc cttcctctct caccctcata 133741 cccactctca caattacagt ataatgtgct ggagaagtga ttctccattg tggttttcct 133801 caattcaggg ggtactcaac aatcttaagc aaggggttat gtgtgagggt taaaatcagt 133861 tttcaatgaa gtcagtatga agctatggac attcttactg gatatcaggg tatcattaca 133921 gtgaacactg aagtatactc atgaagttta taaaaattgc agttcagaca cccatccttg 133981 cttctgtgag tggggtttca atagaagata gaccgaagca tgtttaatat ttcctctatg 134041 tgggtgaggg ttaggactct gtgtgaatat tccaccagtg taatagtaac aaagaaaata 134101 attctcaatt ctgataatct tggYttgaat tctagttctg ccagtaacta taggatttta 134161 gatgagttac tttatttttc cagtctataa attattcatg ttcaaatggg gatagtaata 134221 gaaccaacct catggtggta ttatagagat taagtttatg taatacatat aaaatgatta 134281 gcttaaggtc tgRtacataa ttacttgata ttagctagtt gttattatta ttacacagac 134341 aatgaactag agctgtcaag ggttaagaac acctctatgg cagggtgaca aacattgttc 134401 agctggaaca ttatgtgcac ttttcattat cqatgtcagt gttcccctcc gctggcccag 134461 ataattgacg gttctctata cttttattca gttttttaaa aaagtgttaa catcatctca 134521 ttaaatttca catctctatg cagttagtgt ctgttagaaa ttgctgatta gccctctgta 134581 tttccacgtc tctaaagtgg tatctcaagc ctacactcta agtagggaag cgataagcag 134641 agaatagttg tcccataaag ctgtttctca tccatccaca cacctgacat caaaaagcca 134701 aagataatgt ttaaggttga ctacaccttg gtttgatcca gtatctttat ttaaatgtga 134761 tgatttaata aagttgcaag gaaaaaaaga caaaggactc cactttaatt ataaacaaaa 134821 atctctcctt ctgaattatt cttttttttt tacttatttg atgggaagaa ttttattatt 134881 gacctcttta aatatttggc atttggattc tttatttatg tgtacagtaa ttacagatca 134941 gaccatttct gcatacttaa aataggagac tcactttata agaatctaac tctcaaagcg 135001 gagactgtct cttagatgca tcctattcca taggactgtt gttttgtaga ctaggaaaag 135061 ttttagagag aattacatgc ctttgattct tcctatggag tcagcatgat tgatttgtaa 135121 gttacagtgt atttccacaa tgtctacctg tcagtttcac agggcagata atattgattt 135181 ttttaccaca aaatgtggca aagtattaat tttctgccat tgtagtgtta acagaatata 135241 gaatacaacc gtagcagtta atgcatccaa acccagttag ttagatagac tactttgtac 135301 cattggcatc ttcctttact aaatctttct tgtgaatgaa tggagattgt ttttattaaa 135361 attttttttg tttttctaat ttcctcagtt cagttttttc aagtagtaag tttaatatgg 135421 tctatgtctt aaaaataact acattaactc ttttatacaa aactatctat gtagagtgaa 135481 tatatcgttt ttagaaaatt atttgtgcct ttccagaaag agaaaatttt ggcttcctgt 135541 tctcttgcca agtggtgact gtgtcttata cttactctaa gtagtcatta gcagtttatc 135601 tcctaataag aataaaaagg taattttccg ctgctgtgtt tttctttaac ttagattgca^ 135661 ttcattctta aaggagcaca aaagcaaaca cacagacctc tcattctgat tttaaataat 135721 ttagagtgga actgtgaaca caatattttc cccattgaag atcattttat actgaagttt 135781 aatataggtt tttaaatttc tatttaaaac ttgggctcag gagggtgatg gtaaagtgtg 135841 acattcacaa gctgtttcct ggtgatgaaa aatgcatgag aacataaccc acacaggact 135901 agtcaggcga ctttgaatgt aattttccat taaattttac ttgatttaac tcaacacatg 135961 gtttgtatct tacaaatttc ttgaagaaag aaataggtgg tcctaagtga atgtaatgcc 136021 taaagagctc atcattgtaa tcatagttta aattacgtgg aaccaagtta aattcctaaa 136081 aaaaaaaact tacaccctct cctcccttct tctcctccgt ttctttctat attaattttt 136141 gaaatatctt tgtccttcat atacatatac atatatatgt gtatgtatgt gtgtgtgtat 136201 atatatatat atatagagag agagagagag agagaaagaa agaaagagaa agagtgtgtg 136261 tgtgtgttat gggctgaatg gtgttccctt aaaattcata tgttgaagtc ccagccccca 136321 gtacctcaga atgtaaccgt gtttgaaggt aaggttttta aaSaggtgac taaattaaaa 136381 ttaggtcatt gggtgtgacc ctaatataat atgactggtg tccttgcaag aagtgtagag 136441 acaccaggga tcccatcaac cagagggaag gccatgtgag gacacaagag aaggtggcca 136501 tctgcaagcc aacgtgagag gactcaggag aaacaaaccc tgccaaaacc ttgatcttgg 136561 acttctagct tccaaaactg tgaacaaata aatttttgtt cttgaagcca ccaagtatgt 136621 gatgttttgt tatgacacct ctagcaatcc atacatatgt ataaaataaa cccttgttat 136681 ttggttcgga ttttttcttt aaacactgtt aatttgtttt ctcatactga gtgctagcaa 136741 aatttgtgct gctagttttg ttttcgcata ctgagtgcta aatgggagca gattacttag 136801 atgactttaa ggcaaaatat ttaattgaaa ttcagtgtat ggtcttgggc aaatcggtgt 136861 ttctgggagg ttttcatttt tatatattta tattagagta aatgatgccg acagtgttat 136921 gtagctctag gagctctgat tttgtgaggg caagaattct atttttggtc tatatttcat 136981 tataaaatta gtaatcgtgg agcttgagga ggaattgacc ccacattgaa tgcttggtta 137041 ggaaatgggt tactattgtg tccagctgtg cagattgagt acttgactct gcaagttttc 137101 ttgaagcact tactaatttt ccagcagttc cctcaacatt tgccacagtc attcttccat 137161 tgaaggtgcc actgtctaga gataggctgg attaatagtt gagactctca gagatgaact 137221 tgtttcttct ctttttatta gcattaatga tgagtgagag tagttgcctg ataatacctc 137281 ctcagtctgc acagctttag gctaccttgt gctgtataca cctggaaaga tctgacttta 137341 gattttgcaa aaatctgttt agttccacac ataaattaag ttctttttca ttacacagaa 137401 tgaggaaaca acctcatgga agtttatgtg cagtgggttg acttcaacca ttgagccttt 137461 aggatattta caggtgaatt gggtagtaga aaattttaat aagtacctgt tttctacaat 137521 ctctgtggca ttgattttaa gcccttaaca tttggacata tttagagaca tatttgttat 137581 tgtaaggatt aacataatag gttactattt tatggaagag attagtatct aaagcacaaa 137641 tgcttgttaa taactgccaa atagtagaag ttaggtggtt tcctggcttg ttcttgcatt 137701 taaaagtaat ggatcaaata tttcaccatt taatatgagg tttgttacag gtttctatag 137761 aaataatatt gaatttggaa cctttccttt gttactaggt tacataattt tttgatttta 137821 tttcagatac acagtatatt gaattttaaa aattgttttt caggattttt ctcttatgta 137881 gtgaaatata ttagtaattt ttttgaggtt gaaccatttt tgaattcatg aaataaatct 137941 catttggcca tggtatatta ttcttgtagt acatttgcag aaattaattt ttaaaatatt 138001 tcttagaatt tttgctccta cgtttgtgat acttggcctt ttgtttaatt agttagttaa 138061 ttttggtaat ggggttttgc tagttaaaag cattttatat ttttatgcta tctgcttcat 138121 acaacttagt atatctgttt cttaaatttt agtggaagta gcccttagaa gattgtattt 138181 ttaagattaa ttctttaaat ttattctgtt tattgtgtct tagttttttt gtattttgcc 138241 taagtcaatt tgggtaatta attttttcta gaaagtatgt actaaatttt gaatattttg 138301 gtataaagct gttcatagtg ttccaggtta attaatgaaa acaaaaacat tcgttcttaa 138361 actgagttat gttctctttg tatttccagt gtttatttag ttctcttttt aatgagactt 138421 tccagataat tatctatttt aatggtcttt acaaacagca tttggtttta ttaatcatgt 138481 ttataatact tttgtcttat attttacaga tatcttttat tgtctttatt aatctcttcc 138541 taccgtgttc tttgttgctt cttttctagc tgccattaaa agtctacgtc atactgcttt 138601 attgttttct attatatgca tatatttaaa ttttctttta tgtattggtt tggctgcatg 138661 ccataggtct taaatggtca tgctctcatt gacacatatt tatgaatttt aagttttgat 138721 ttttttaaac ccatgttatt aaactattca gctttaattt ttttattaaa aaaaaccatt 138781 tattgtgtat atttaagata caaagattca gtatccccta tcggaaatgc ttggtacgga 138841 ggtattttgg ctttaagatt tttttggatt ctggaatata catgagatat cttaggaagg 138901 ggaccccaag tctaaacatt aaactcactt atgtttcata tatagcttat atgcatagcc 138961 tgaatgtaat tttatacaat attttaaata attttgtgca tctatcacat gaggtcaggt 139021 gtggaatttt ccacttgtgg catcatgctg atgttaaaaa agtttcagat ttttggaaca 139081 ttttggtttt aaggtttttg gattagggat tctaacctat atagcgtggt ggtatgggat 139141 acatatagat agtaaaatga ttactgtagt gaagcaaatt aatatatcta tcatctcata 139201 tagttaccca ttttttgttg ttgtggcaag aacagctaaa atctactcat ttagcaggaa 139261 tcccaaatag agtacaatgt tgttaattat agtcttaatt tctaatttaa ttgcattgtg 139321 ttcagaaaaa gcaacttgaa atgtttttgc aggtttcaat attgagctca tctttgtgac 139381 ctaatctatg attttttttg gtgaatttta gatgtgtgct tgaaagaata taaatatttg 139441 aatacatata ttaattaagc cgctgtttct agtatttgag ccccatatat cccttaatta 139501 ttagttactt gcttgctctg tcgattagta gtgtatgctt gtctttcatt atcacttctt 139561 tctcacttta ttgctaccaa caattgtttg atacatttca aaactatgtt atttggcctt 139621 tactagttta ctagtttatt agacttcttg gtggattttt aacattcatt ttttatggga 139681 gatattaatt taatctattt attgttttgt aaattctgtt ttgtctgcta tcaatactac 139741 tataggtatt attttaaaaa atgcttactg ggctatattt tccccttctt tattttcaga 139801 tttactcttt tttaatctct tcttaatagc atattgctag attttctttg ttttttttat 139861 tttttaatct gagagctttt cctttaatag gggaagttga ttcgtgtatg tttattgtaa 139921 tcattgatat gtttggattt aactttattc ttttttttta aattatttat ttttattgat 139981 cattcttggg tgtttctcgc agagggggat ttggcagggt cataggacaa tagtggatgg 140041 aaggttagca gataaacaag tgaacaaagg tctctggttt cctaggcaga ggaccctgcg 140101 gccttccgca gtgtttgtgt ccctgggtac ttaagattag ggagtggtga tgactcttaa 140161 ggagcatgct gccttcaagc atctgtttaa caaagcacat cttgcactgc ccttaatcca 140221 tttaaccctg agtggacaca gcacatgttt cagagagcac agggttgggg gtaaggtcac 140281 agatcaacag gatcccaagg cagaagaatt tttcttagta cagaacaaaa tgaaaagtct 140341 cccatgtcta cttctctcta tacagacacg gcaaccatct gatttctcaa tcttttcccc 140401 acttttcccg cctttctatt ccacaaaacc gccattgtca tcatggcccg ttctcaatga 140461 gctgttgggt agacctccca gacagggtca tggccgggca gaggggctcc tcacttccca 140521 gtaggggcgg ccgggcagaa gcgcccptca cctcccggat ggggcggctg gctgggccgg 140581 gggctgaccc ccccacctcc ctcccggacg gggcggctgg ccgggcagag gggctcctca 140641 cttcccagta ggggcggccg ggcagaggcg cccctcacct cccggacggg gcggctggcc 140701 gggcaggggg ctgacccccc cacctccctg ccggacgggg cggctggccg ggcggggggc 140761 tgacgccccc acctccctcc cggacggggg ctgacccccc cacctccctc ccggacgggg 140821 cggctggccg ggcagagggg ctcctcaact ttattcttat tttataaaat tttacttagc 140881 atgctttctt attgaatatg ccttctcctc taacctctca ctccttaccc tcttcctctt 140941 tcattgcatt ttttttccat tcccctctcc ccaatttgtt tgggatttgt ataccttatt 141001 tatatcaatt tactgattac cttttaaagg ttaagaaaca tcctaaaaca tatgcatttg 141061 gagtttcaat ctgtatctgc aatatattct gatttattca agaaagctca gtgtgctttt 141121 atttctcctt tcctactgtt ccttgccttt tcccccatca ctccaactac atcttatatt 141181 gagataattt tttgtctaga tttttttctg tgggtaataa aattgttgtg tttccataat 141241 tcacttgagg gaccgtcttg agtatagtat taattatgca aaattatttt tccttttaat 141301 tttgaaaata ttgcttaact gtctttttgc accgattaMa atctatgaca atatgcttgc 141361 tgaataattt ttctatttag atgtaacctc tccctgaagt tttctgggag agttctgttc 141421 agccattgag cttattactt ttttaacctc tgaggttcaa gcagttctcc tgccttagcc 141481 tcccgagtag ctgggactac agacttgtgc caccacgccc agctaatttt tgtattttta 141541 gtagagatgg ggtttcacca tgttggccag gatggtctcg atctcttgac ctcgttatct 141601 gcctgcctct gcctcccaaa gtgctgggat tacaggtgtg agccaccgtg ctcagcctat 141661 ttaaagttat ccttaccttt gcagtgttaa cttgccttcc aaggttttag cttatctgcc 141721 cactgaattt tatccatctc tttcaggata ttgattttcc taaaatgatt tgtgattttt 141781 ggttgtatac tcatatttgt acttgagaat cactgtcagc ttattttatt ttctgtaaat 141841 tttctctact gattgtgtga aagggattac agcttggggg atggggagac attgcttttt 141901 ctctgggtat tggctatttg agtccttgct ctgctcagat accacactct aagctgtctc 141961 ctgtgcagat gcctccacag cttgcttggg aggacactgc agtctcaact gtttatgtgt 142021 tgattagtct catgttcacc tagaggttct tgcttctttt atttaatagt cttcccctac 142081 atggtcaggc ttttctctga agttttgatt ctgattacct tctttcagaa ttcttcaaaa 142141 tttctgatta gatattggca ctcttttttg ttttctgctt ctaattctga tttattgttt 142201 ttgaaaaata acttttaagt catgatgggt attttgggcg ggaagaaagt aagaaacatg 142261 tattcaactg gccacataaa atcccaataa atagtgggag tcagaatcat tgcccacata 142321 ttgtgtgttt tttgataagt gatacaggtg tatattcaaa' agtagtgttc aagcccaact 142381 tgaagaatac aagttctaaa cttctgaagt tggttattta taaagtacca caaatattag 142441 caacttttta tgaattatat gtatatttat attggaataa atctctttaa taagatattt 142501 ttcattcctt atataattat cattttctaa tatgctttgg tattaccctt ttatataata 142561 gcaacagtat aataatagat catgtcttat tgaaatagaa ggtgaatgct tctccaccat 142621 ggaggacaac actccccttt tcttgttcca tagttaaagt tggggtggga gttgagtaca 142681 ataagattga tgaggtcact ctctcttagc attttttttg gtcctgttgg gaagtgacct 142741 gtcttaagag ttgttttgtg gcagctatac cttaaggatt gatttatgta tatataagag 142801 agttccattt tgtattagtg atagctgagt gatacatctt ctgattatct gtttgaatta 142861 tcactaaaag gtatcagaag agtaccttta tataactgaa tattatacca tcatgattta 142921 caatgggata cagtaaatat tttcagcttt gtcagccata tgatctgtat tggaactaca 142981 gctgtgttgt agtttgaaaa ccatgaaaca atatgcaggt gaatgaccac gactgtgttt 143041 cagtaaaact ttatgaacac taaaatttga ttttcatatt attttcacat atcatgaaac 143101 tttatlcttg ttttgctttg cttccttcaa ccattagaaa aggtaaaaac tattctaaac 143161 ttatgggata tacaaaaaca ggtggtgggc tggatttgac ccatgggcca cagtttgcca 143221 gctcctaatt tagaagatgg tataataaca tgtaaagtgt tcataattga ttgaataaaa 143281 aaagggaggg gcaggtttaa aaacagtaga tatagtgcaa tttcatttat gtaagaaagc 143341 aatcatcagc ttacagatag cactggaaga acagctatca aaatattaac agtggtttcc 143401 tggttagctt atgggaataa tttcgttcta cattgtgttt atttgcattt ttttttagtt 143461 ttgtatcctg tttattatgt tgttttgaaa aataaacatg tatgccagaa aaaacagtta 143521 tttaaaaagt gacagagaat ctgtacattt ttagcaaaat cagggtattt gttgttaatt 143581 aatttgatac aatctgtttt gtttaccctg tgcttcattt ttagccaaca agtcccaaat 143641 ttggaaaagc tgactcatat gaaaagctgg aaaaactagg ggaagga.tct tatgctacag 143701 tatacaaagg gaaaagcaag taagttcatt atttttggaa tatttcacat gtacagtgta 143761 tctgccctct tattactaaa tagcatttta tttaaataat tattatttaa tatacaatag 143821 attttcctcc ctcacggtat cctttttttt tttttttttt ggcaagtgtg taaaactcat 143881 tggaattggt gtaccctgct agtaaacagt ttttcagact gttcaattta tttttctgtt 143941 taatgcgcct ccccacaaca ctgctttctc tttcaaagga gttggaaccg tctaatgaga 144001 attcatttcc aggtgaatta tgtgattaat ttctcataga gatttagtgt tgggaatagg 144061 agtattgatt tgacaatgcc aaatatattg gccattcttg gggtcttttt aagttaagct 144121 tttactccat ctttcagaag tctcttagtt aaacaaaatg gcaaactttt ctttttcttt 144181 cttcctgtct gctttggcat catgctgcat atattttcat atcgagaaac aactgtctcc 144241 tccttttctt ctttctctcc attgctctct gggggtcagg gcacagattt ggattcttga 144301 aaagcttgtc ctcatgtgtt tctgattgac ctccttactc tcccttatta attaaggaca 144361 gagagttact gtatttagtg acatgtagtt gtagataact taatgcaatc tctgcaacaa 144421 ccacagaagt cacaagcttt gttttacctt tataacttta ccaaatgatg ttgcaaaata 144481 attttctata ctgtccctgt tatctctttt caaaatcttt atagaagata ggactttttt 144541 gtctgagaca gcatttcgcc ctgttgccca ggctggagta cagtggcttg ataacggctc 144601 attgcagcct caacctcctg ggctcaaaca gtcctcttgc cttagcctcc tgagtaactg 144661 ggactacaag cccatgccat catgtctggc tatttttttt aaaaaactct tttgcagaaa 144721 cggaattttc ctgtattgcc caggctggtt ttaaactcct gggcttaagt gatcctctgg 144781 cctcggccac ccaaagtgtt gggattacag gcatgaacca ctgcacccag ccagattaga 144841 atattgtaac ttaagtaatt aaataagaag atgtagaaga gaaaaattct ctgaaggatc 144901 attccaaaga catagttgga aattttgatt atgtgctaat ttaggtaatc ttaggatttt 144961 caggagtgtg gtcttatatc tgtttgttca tgtttcttaa gtttagaaga tgaaatattc 145021 cttatcaaga aagatatgta aggcaaaaat actgtgaagt caaaagtaat agtattaatt 145081 ttgagagttg taaaaaaaag tttgtaaaaa tggtgcaggg agccctcttc attccacacc 145141 cgggcagatc tccaggcctt tggagcaccc gcttgcctcg ttctatatct tgagctgccc 145201 caccccttct gtccagagat cctggtatag cagagccttc ttcactccat gcccagtcag 145261 atctccaagc attcaaagca cctgctcacc tcatctggat tggcaacctc agttgcccca 145321 cccttccttt gcagacatcc aggtgcagga ggggcccttt ctgctttaca tccaggcaga 145381 tctccaggca gttagagcac ctgctcactt tgttcagcat cctgagtcac tcactcttcc 145441 tgtgcagaga ccatggtgca gctaggcctc tgctccacac ccaggcagat ctccaggcat 145501 ttggagcacc agttcacctg gaatggcagc ttaagctgcc tcaccctttc tacacaaaaa 145561 ctctggtgta gcaggttcct ctctcctcca tgccccagca aatctccagg gatctggagc 145621 acttacactc ctggattagg agtttaggct gcctccactt cctctgcaga gacttggggc 145681 taaggatgtt tcccagcttc atgtttaggc acactctggg tgcttggtgg ctttctactg 145741 gattctccat cagtgctggt gcttgtgcct gctatcaggg gatgaccatc ttgcctcatg 145801 cccccaggac tgagaaggga actcagaaca ctatgggctc cacagatcag cccattgcct 145861 aaggcaacag agagcatctc cccataaata aggatcaagt atatatccag acacattggc 145921 tgcagtaggt tcttactgat aagtgccatc tactggctgt aggtcaaacc aaacagccgt 145981 atgtaaaagc tgctgataga aatgcatagg gctatagaag caaagccaaa agatcctacc 146041 cagcattctc tgcagttgca acacagaggg agtggggaga agggaagggg aaagaaaaca 146101 cacacacaca cacacacaca cacacacaca cacacacaca cacaccaata atattacaga 146161 gaaagaaaaa gaaaaaatgc aatctgtaca aaaataatta caaaaattat agtgccaaca 146221 tctccagatg agaaggaacc agcaaaagaa ttttgttatt gtgaaaaatc tgaatgtctt 146281 ggcaccgctg aaggatcaca , ctaactctcc agcaataatt cctgaccaaa atggaaactc 146341 agaaatgaca gataaataat tgaaagcatg gattacaagg aagcttagtg agatccaaga 146401 catgattcaa aatctacaca aagaaacttc taaatcaatc caggaaatga agaaggagat 146461 ataacatctt aaaaggaaat cagtcagcgt ttctagaatt gaaaagctca cttaaggaat 146521 ttcaatacaa ttgaggccgg acgtggtggc tcacacttgt aatcccagca ctttgggagg 146581 ccaaggcgag cggatcatct gaggtcagga gtttgaaacc agcctggcca atatgatgaa 146641 accccatctc tactaaaaac agaaaaatta gctaggtgtg gtggcacatg cctgtaatct 146701 cagctactcc agaggctgag gcatgagaat agcttgaacc tgcgaggcgg aggttgcagt 146761 gagctgagat cacaccactg cactccagcc tgggcaacag agcgagactg tctccaaaaa 146821 aaaagaaaaa aaaagaaaag aagaaaacag ttgaaagctt caatatctta gaccaagtgg 146881 aagaaataat ttcagagctt gaagaccaat cttcttaacc cagacaaaaa taatattttt 146941 ttaaatgaac aaaatctttg agaaatatgg gataatgtaa agtgatcaaa ccttcaaatt 147001 attggcattc ctaagtgaga cagagaaaag gtaaacaacc tggaaaacat atttgaggga 147061 ataatcccag aaaaatcccc taaccttgct agagaggtga atatccagat tcaaaaaatc 147121 tggagaacat ctgggagata ctatataaaa tgaacaccac caagacttac tcaccaggat 147181 gtctaaggtc aatgctaaag aaaaaatgtt agaaagaaaa aagcaagatc acatataaag 147241 ggaacaccat taagctaaca gcagatttct cagaagaaac cttacaagcc aggagagttt 147301 gggggcctgt tttcaccatt cttaaaataa atctcggcca agaatttcat atcccaccaa 147361 gataagcctc atacgcaaag gagtaataaa atgttttcca gacaagcaag tgctgaggga 147421 atttcttacc actagatcag ccttacaaga gatccttaag ggtgttctaa acatggaaat 147481 gtaagaacaa tacccactac cacaaaaaca cacataagta catggcccac agattctgta 147541 aaggcactat acaatagaaa ctataatgca accaagtaac aacttcatga taggctcaaa 147601 atgctatata tcaatattaa ctttgaatat aaactgacta aacctcacac ttttaaaggg 147661 catagaattg taagttggat taaggaaaga aaaacaagac ctatctctct gctgttttca 147721 ggagacccat ctcacatgtg attacacaag taggctcaaa gtaaagggtt ggagaaagat 147781 ctatcactca aatggaaaac aaacaagagc aggggtcact atttttatat cagataaaac 147841 agactttaag ccaacaacaa taaaaaagga gaaagaaggg cgttacataa tgataaagtg 147901 ttcaattcaa caagaagact taactatcct aaatatatat gcatgcaaca ttggaacaac 147961 cagattcctg aaacaattac ttgtagacct acaaaaggac ttagccacac aataatagtg 148021 ggggcttcca caacgcactg acagcattag acagatcatc aaggcagaag accaacaagg 148081 aaattctgga cttaaattct acccctgacc aactagacct aataggcatc tacaggatat 148141 tccactcatc aaccacagaa tatacattct tctcatttgc atttaggaca; gatgaccaca 148201 tgctcagtca taaagcaagt ctcagtaaat taaaaaaaaa aatcaaagtc ataccatcca 148261 tactcttaga ccacagtgga ataaaaataa gaatcaatac caagaggatt tccccaaact 148321 ttgcaattac atggaaatta aacaacttcc tcctgaataa cttttgatta aacaattaaa 148381 gcagaagtca aaaaattctt agacataaat gaaaacagag acaaatcata ccaaaatcct 148441 tgggatacag gaaaaacagt gttaagagga aagtttacag cactaaatgg ctacctaaaa 148501 aaattagaaa gatcttaaat taactaacat cactcctaga ggaactagaa aaacaagaac 148561 aacctaaccc caaagccaga agaagaaaaa acataactaa aatcaatgca gaactgactg 148621 gaattgagac ctaaaaatat attaaaaata aatgaaatca aaagttggtt ctttgaaagg 148681 ataaagatca atagaacact aattaaagga agagagaaga tccaagttaa cacaatcaga 148741 aatgacaaag gtgacattac agctgatccc atggagatag aaaagattgt cagagactat 148801 taggaacaac tctatgtata caaagtagaa aatctagagg aaattggtaa atttctggaa 148861 cacataacct cccaatattg catcaggaag aaatggaaac tctgaacaga ccaatatcaa 148921 gttccacaat tgaattaata ataaaaacct accaatcaaa aaaagcccag gactagattg 148981 tctcatagcc aagttctacc agaagtgcag agaagagatg gtatcaattc tactgaaact 149041 attgcaaaaa attgaggaag atggacaccg ccttatcatc gaggatgatg aagccagcat 149101 catcctgata tgaacaacta ggaaagaaac ' aatgaaaaca gaaaactaaa agccaatatg 149161 cctgatgaac aaaaatccta aacaaaatac cagcaaacca aatccagcag cacatcaaaa 149221 agatcattca ccacaatcaa gtaggcttca ttcctgggat gcaaggttgg ttcagaattc 149281 acaaatcgat acatgtgctt caccacataa cagaattaag aacaaaaacc atttgatcat 149341 ctcagtcgat ttgcaaaaag gctttgataa aatccaacat cccttcatga taaagaccct 149401 cagtaagcta ggcattgaag gaacatagtt caaaataata agagccacct atgacaaacc 149461 cacagctaac atcatactga actgacaaca gctggaagca ttcctctaca gaactggaaa 149521 aagacaagga tacccactct cgccgctcct attaaaacat agtaccagaa gtcctggcca 149581 gagcaatcag gcaagagaaa gaaataaaag gcatccaaat aagaaatcaa gtgaaattat 149641 ccatctttgc tgacaatatg attctataca gagtctaaag agtccgccaa aaagctcctg 149701 gaattgatga atgacttcag tacagtttca gaatataaaa tcaatgtata aaatccagca 149761 ttatttctat acaccagcag cattcaagct gagaattaaa tcaagaatgc aatttcattt 149821 acaatagcca caaaaaatta aaaggcctag gaaaatgtct aaccaaggag gttaaagatc 149881 tctgcaagga gtactacaaa acattgctga aagaaatcat agatgacaca aacaaatgga 149941 aaaacatttc gtgcttttgg attggaagaa tcaatattgt taaaatggcc atgctgccca 150001 atgcaatcta ttgatgcagt gctattccta tcaaactgcc aatgttgttt ttcacagaat 150061 tagaaaaaca tattctaaca ttcatatgga atcaaagaag agcttgaata tccaaagcat 150121 tcctaaggga aaagaaccaa gacagaggcg tcacactacc tgaattcaaa ctatattata 150181 aggctacagt aactgaaaca gcatgatact agtacaaaaa tagacacata gaccaaagga 150241 acagaataga gaacccagaa ataaagccac acacctacag ccacctgatc tttgacaaag 150301 ttaacaaaaa taagtgatgg ggaaaggact ccctatttaa taaatgtttc ttgtatagat 150361 ggctgtccat atgcaggaga atgaaagtgg atccctccct ttcaccatat ataaaaatta 150421 actcaagatg gattgaagat ttaaacgtaa gacctcgaaa ctctaagaat cctagaagaa 150481 aatttaggaa acatcgtctg agcatcggcc tttggaaacg atttatgact aagttcacaa 150541 aagcaattgc aacaaaagcc aaaattgata agtgggacct aattgaagag tttctgcaca 150601 gcaaaataaa ctatcaacag agtaaacaga atgggagaaa atattcagaa actgtgtatc 150661 tgacaaagat ctgatatcta gaatctctga ggaacttaca caatttaacg agcaataacc 150721 aaataactcc ataaaaagtg agcaaaatac atgaacagaa acagacactt ctcaaaagaa 150781 gacattcaag cggccaacaa acatgaagaa atgctccact cactaatcat cagaaaaata 150841 caaatcaaaa ccgtaatgag ataccatctc aaatcagtta gaatggctat tattaaaagt 150901 caaaaacagg tgctgggaag gctgtgtaga aaagggaacg cttatacact .gctggtgaga 150961 atgtaaatta gttcagccac tgtggaaatc agtttggaga tttctcaaag aacttaaaac 151021 aggaactgtc attcatccca gcagtctcat tactgggtat atatccaaaa gaaacgaaat 151081 tgttctacca aaaagacaca tgcagtttta tgttaattac agcactattc acgatagcaa 151141 agctgtggag tcaacctaca tgcccatcag tagtgaattg gattaaaaaa atgtggtaca 151201 tatacaccac agaatattgc acagccatta aaaagaatga aatcgtgttc tttgcagcat 151261 catggatgca gctggaggcc attatcctaa gtgaattaac acaggaacag aaaaccaaat 151321 attgcatgtt ttcacttgta agtgggagct aagcattggg tacacttgga cataagttgg 151381 gaacaataga cactggagac tgctgagtgg ggttgctaag gaagggggaa aagggttgaa 151441 aaacctttgg gtactatact tactacctgc atgacaggat cattcatatc ccatacctca 151501 gaatcatgca atatactaat atgataaacc tgtacatgta gcccYgtaat ctaaaatgaa 151561 agttgaaatt acttaaaaag tattttttta agaaaatttg aatgaatagt cagcatgata 151621 agggataaaa aacaaaatcc agaggactgt taataaccat attgcttgag aattttggaa 151681 tgtcaaagta atggtctaaa tgattgagtt aattttaata ggggttgtgc cccatatttt 151741 aattttcttt cctaaagaaa aatagcagta ctttaccata taaaaattac ttgtactaaa 151801 tttagtgtca ataacatgat aactaccctt tattaagcaa ttattttgtg tacaatatag 151861 tacatccctt tgtctcattt actcctcaca atgccRtatg aggtgggtcc cattattgtc 151921 atcttcattt aacagtcagg aatcttaggg cttagagagg tttagcatct tgcctatgtt 151981 cacacaggta gttagtggca aagtttgttt agctcattcc catctggtgg cttgaagcta 152041 tcattttcct aatcagtaca ccattactgc ttccatagtg caagaccttg gaaagatgtg 152101 atcctctctg aatattccaa atagttctca catatactct gacttgtttt aattatgact 152161 caaatagaag caaacactat ttctttataa gaaaacgaac cacttggaag ttcctaYcca 152221 ttgaagatgt gctcagctga tctccagatg tgttaataac tctattaaat ttttatcttg 152281 aagatttatt tcaaaatctt ggagaYagtt gaagaatttt tcatttatta tgcctgaata 152341 aaagaaagRc tttaaaagta cctataatct ttgagaaaga ttgttctgga cggttaatag 152401 ttttcactct agtaggtatt aatttatctt gttagcattt cttgagcagt ttcaagcctc 152461 ctggtcacat gtagtacttc ctttcctcca ggtggagagg aaagccattg cctagttacc 152521 tgctttaaga gatgacaggc tccctggctt tgcttgcttt aaggtggcta agtcaggctg 152581 aagaataaca gctacatgtc atatagcagg acttgagagc taagtttggt gtgtccctat 152641 agtgctatat aatttaaata gccaactaat tgttgggatc cctgttccaa tactcctcac 152701 cattctctca taaatgtctg catcccacct gccatcttta aacataatct tttgcatcct 152761 ccccagaaac agctctcatt atcttgcagt gaagctgtct ggcatttgta gagatacttg 152821 tgattttcag tttgtgagca ttttacacat atgtgttggt ttacaggtgt catgtttgga 152881 ttttaccata agcttcattg tattagtttg ctagggcttg aaataacaat gtcccacaat 152941 ctgggtggct taagctacat gtactttctc agttctagag gctagaagtc tgaaatcaag 153001 gtgtctgcag ggtaggttcc ttctgaggat tgttagggag aatctgttcc atgcctctgt 153061 cctagcttct ggtggtgtgc tggcaatttt gggcattcct ggcttgcagg tgcatcaccc 153121 ctcttgttgc cttctccaca tggcattctt ccagtgtgtg tgtgtgtgtg tgtgtgtgtg 153181 tgtgtgtgtg tgtgtctgtg tgtgtctgtg tccaagtttt ccctttctgt caggacRtga 153241 gttatatttg attaaggtcc accctaatga tctcattttg atttgattgc ctccataaat 153301 gactcatttc aaaaaaaaat gcattctgag gtgcttgggg ttagaacttc aacatatctt 153361 tttgaacagt tcaatccata acacttacta gtgtcaaacc tcactaactt ggcattgcat 153421 tcatgacagt gttgttcttt ttctgcctgt aatacgtgtc attcatcctt tacctattgg 153481 ttctttttaa agtacaaaca aaggatattt atttgcccca tcaagagatt tgtgtaattc 153541 tttttttttt ttttgtttga gacagggtct cactctgtcg cccaggctgg agtgcggtgg 153601 tgcatgcagt cttggctcac tgcaacctct gccgctgagg cttaaccgat tctcatgcct 153661 cagcaccccc gagtagctgg gactacaggc acgtgccacc acacccagct aattttcata 153721 tttttttgta gagacggggt tttgccatgt tgcccagact ggtctcgaac tcctgaacta 153781 aagtgatcca cccacctcgg cYtcccaaaa tgttgggatt acagacatga gcaaccatgc 153841 ccagtggRtg tgtgtaattc ttgattgtgg agtagttgct attaggcata gtttagaagc 153901 ttgaggagga atagaaagtg tttttaatta ttcttgattc ttttggatct cttatccatg 153961 taggaacaca tacactggag agaagttaac tgagattcct atacaggtag tctgctttgt 154021 agtgagcttg gcttctaaca aatggctggt taaccctgtt cacatcaaca tacaaaactc 154081 acaaatatgc ttttaagaaa aagctttgaa cttaccacat tctcatattt gagtagaaag 154141 tttttgtttt ttgatcagtg ttctccagat ttcttctctg tctctctctc tgtctttgtc 154201 tttcactgtc tctttgtctc tctctctctc tctctgtttt tatgtttaga tggggggtgg 154261 cagttatcat tacttctgac tgctgactgc tgatctctct tctggtttgg ttttctgatt 154321 atgttctctc ttctaaattc ctgtagcatt taatatagga ttaaaaaatt atgcatcgta 154381 taatactttg gaaaattaaa atatatggca ttttaaaatg tctttaattc agcaccttga 154441 aatcatcttt ttacctctca gtttaccaag gacttctgta tattcagaga tgtgttaata 154501 ttttttgaac ttattcaact agtgatgaat attcattgta ttgtttataa ttatgccttt 154561 tttatgctgt cggtgaaaaa gaggtgactc agatgaggat tctgccctcg ggaaacttaa 154621 tcttgaaggg agatggtaca aatacataag taattctata taaatgaaga tgtatcaata 154681 ctatattcta tataagctag aacgtagtga gaaaggccca ggtacacagt ggctcgtgcc 154741 tgctatccca gcactttgca agggcaaggc gggtggatca cctgaggcca ggagttcgag 154801 accagcctgg ccaacatggt gaaagcctgt ccctcttaaa aatagaaaaa tcagctgggt 154861 gtggtggcat gcacttacaa tcccagctac tcggaaggct gaggcacgag agtcactcaa 154921 acccgggagg cagaggttgc agtgagtcga gattgcacta ttgcactcca gcctgggtga 154981 cagagcgaga ctctgtctaa aaaaaaaaaa aaaaatcgta aaacaaaaac atccaggtaa 155041 aatggtgtgg ggtttcaaag ggaatgaaga gaggatgatg ttgactaaag tattttaaat 155101 gttttctctc cagtggccac tgattgagtt Yagaagccac atctttgtgt gcttttaaat 155161 caagcttccc tcatcactat gtgtctttgt ggaatccttg gcactgttcc cttttggggc 155221 ttactccttc cccccaRgca aatataatga gatattcact cattggttat cagactctcc 155281 actaaatttg ttgaactttg agggccttaa gctaaaagta aacagattca ctttgattat 155341 tgtggtagtt ttggttaagc aaaagtgttt tgtttgagta ttgaagtgga attggcttta 155401 agcaatatga tctgggagga ttggtggttt gcttatgcaa gggcacccat gaatacctgg 155461 ttgttgaaaa taagagctac tacctctcac aacctcaaga cccaaagttg agacatagtg 155521 ggacccatat tctcctcaat gtactttgat ctgctggtag atcacacctg agtcccccag 155581 gttctgcacc ctacctcaag tagtgagtgg gtatgagtct ttgctctccc tggggcaggg 155641 tcctctcctt tctttcctac tgaatctagg gggtatgtga gtctatagct gcttttgatt 155701 ttctcagact tcacatgcca tttagaggaa aaacagcttg ctctttgttc tgcttctaga 155761 attggagtat tcagactaag ttgtcccaca gatgatcctg atctctggtc actttYtctg 155821 cttatgttca gtttctgttg aggtgaagat gccaaagcat tacttctgca ggagcctgcc 155881 aaagaaaagc ctgcccacac tggtttgtgc cagccataaa ttgttatctc agaggtcaat 155941 gagaacaatg aaggaatttg ctcactttat gtgacatgag atttatgtga ttgaaagtgc 156001 caatcttctt ttagcatttc atcctgccaa tttgtgcaga ataattgaac ttgaattaaa 156061 cgacctYata aattgagaga ctacaccaaa ccaagactga aatatactaa atacagttca 156121 aagagctctt caaaacccca ggagaaatag gggggaagaa atgctattaa ttaaaacaag 156181 cagcagcgca agaagaaagg cagcagcagt taaccacctt ttcacaatat gtgagattaa 156241 agatgcagtt cttactgctt gcactaaagg tcaaSttcat tgaaacacta tcaggaggag 156301 tttgaagaat tctagaagtc agtaatcccc agatggaaaa cactggattc ctggttcatt 156361 gaagctgcaa tcttaagtgt tgacacctag actgtcatgt ggacttcaga gtcctgagag 156421 gttacctgcc cacaaatggR agctttctac aaagagacac tagtctgatt acattttaca 156481 agctctgctg taggatgctc ccgaggccca tgctgtttct ccttaggtct gctctgactt 156541 cttttagact ttgggctctt ggaccaaagc ttattattac agctcacttc aaagatcaag 156601 cctgtaactg cactatttaa tcaatgaaaa taacatcaca gtataataca atcagtgtta 156661 gttttataat ttaatgaaca aaatacagca ttacaatgta taacaggatR aactgaggga 156721 agaaaagcta acagagtaaa tgcagttcac aatatgggat tttccgatct gtgttccttc 156781 agatctgtgt ataggtgaaa gtttgaaaag tagggttcct atccttaSct agtccaagga 156841 ggataatagc ccacccacca acatctgcta attttatttt atttttaaac cctaaatcct 156901 actcaaattg cagattcagc cctgacgtcc tttagaggaa gaatgcagac attagagtct 156961 ggttcattgg tacagctggt ttcatttagc ttgcagcaga taaacaaaca atgcttaatc 157021 tttttgatga aagtgacagt gaggatattg tttaagcaag aagatgattt taattattag 157081 actaaattgt actggaataa ctttcctatt agacagtgtt taaacgtatt ggcctctctt 157141 agccatgttt attatcaggt tctttgatca tttggacagg agacgctcaa tacaatcagt 157201 gatatttgct gttgttaaaa ttgtggtcat atgtcagcta tgcccatctg gtggaaatgg 157261 aggcactctt tggggttttt ttttttttaa agagttagtg tagaaatgtt caattactga 157321 aataattgaa agtcattatg tgaggactcc taaaacccct ctcccaaagt ggtttttgag 157381 gaggacttgg ggaaggatat aattgacttc aggttaaagc atacccatgt tcctgagctg 157441 ctttattgtt actgtcatcc ttttgtttaa accaggatgg tagggaagga gcatttctag 157501 tctaaaccag tggttctcaa ctagggataa ttttgtttgc caggatatat ttgttggtgt 157561 ctggagacat ttttggcttt cacaacttga ggagtggtgg tgtcactggc atgtagtggg 157621 tagaggccag agatgctgcg gaatatccta tgaatgaaca ggacagtctc ctgcaacaaa 157681 gaattatttg gcccaaaatg acattagtgc tgagattgag aaaccctggt cttaagaaat 157741 gcatggaggc agtgtctgtt taagatagtg cattcctttt gaggttgtag taactctcta 157801 ctgtgttctg tgggctgagt gggccaggca ataggtgtgt agtggtgaac aaaattgaca 157861 ggtcccctgt ttttattaag catattatcc agtgagggag gcagaaatta atcaagtcag 157921 cagacagaat ctgtaattgt aaattatgta aaggaaaaga gagctgagga agaattaaga 157981 ccgagagtag tgggttatgt atatttgcat aagagagggg tatagatagt aaatatacat 158041 tggatggatg gaaatggaag ccttgttgag gagaggacat ttatgcatag gtctgaagga 158101 ggagatgtca ccaggcaggt aaagagcagg cacaagagtg tttcatgcca ggccctgagg 158161 tgagaaagag cttggtgtgt tttataccaa atgaaggagc taattttatt ttattttttg 158221 aggtatggta ggactcatag ttttctcatt gtactgggat ctgctgKtgg gtcacatctg 158281 agtccctcca gggtttggca ccctccctca agttgtaagt aggtgtgaat ttttgctctc 158341 tctgggatag ggtcctctcc tttcctccta ctgaatcaag ggggtatgtg aaaagtgaga 158401 gagcacaaaa acaatgaaca gataagttac aaacgtgaca gatattaata cagacatatc 158461 aaaatcactt aaaatgtaat tggtctaaag ataccaatta aaagacagag attgtcaggg 158521 tggataaaaa aacaagaccc aactatattt tatctatgaa ctatccttta aatacaaagg 158581 tgcagattga aagcaaaaag atagagaaat atatgccatg ttaacgcaaa ttaaaagata 158641 gctggaaggc ccggtgtggt ggctcaccct tataatccta gcactttggg aggctgaggc 158701 gggcagatta cttgagatca ggagtttgag accagcctgg gcaacagggg gaaaccctgt 158761 ctctaacaaa aaacacaaaa attagccagg catggtggca catgtacctg taatcccagc 158821 tactcaagag gctgaggcag aagaattgct tgaacccgga ggcagaggtt gcagtgagta 158881 ccactgcact ccagcctggg caagagagtg agaccctgtc ttaaaaaatt aacatagctg 158941 cagtagccgt gttaatttca gacaaagcaa gtacttctga tgattcagaa gatcatcaag 159001 attaaagaga ggcattacat gatgataaag agcttagttc tccaagaaga caaccaactt 159061 tattgtatac acaccaaaca acagagtgtc aaaatacgtg aggcaaaaat tgatagaact 159121 gaaaggtgaa atggacaaat ccactatggt ggttgtgact tcaacaccac tttgtcggta 159181 attgacagat taagcaggca gagatatcac taaggattcg atgatctgat cagtactgcc 159241 aaagtaaaca aagtggaagc tgccaatatt tcaaggcctg gacccagaac tggcacagtg 159301 ctcctttcac ctactcttga tcaagtgttc aaagagacca gatccaagcg taggggccat 159361 agaccacacc tctcaatgag gagtgtcaat gaatttgggg gccgtgtttt aaaaccccgt 159421 atagagtttg gtttttattc taggctgaat taaatctttg gtctcatctt tgtacacagt 159481 tctctcagct atctgttctg aacatatatt tgctgactcc tttttgggtt aatttcatta 159541 gattttagat ctctccttga gaacaataaa gacacagggt ggggaacatc acacactggg 159601 gcctgtcgtg gggtgggggg atgggggagg gatagcatta ggagaaatac ctaatgtgaa 159661 cgatgagtta atgggtgcag caaaccaaca cagcacatgt atacatatgt aacaaacctg 159721 catgttgtgc acatgtacct tagaacttaa agtatacatt taaaaaaagg ttctgtttag 159781 tataaatggc tttgtataga gggggccctt ctgtcctagt gtacctggca cagttctggt 159841 ttatgcttgt cattttcatg attattaata gtgctctttt tactctgaat actgtcccat 159901 ttggatgata aattatatga tcatattata taatttttat ttttctggaa cttggtaaaa 159961 tattttgcca aaaaccgaaa tttgattgga atatgttatt gtgggatcca actgagtatt 160021 tagagccatt aatgtcagtg aatctgtggg agcatttttg aacagtttat gagtgctgtt 160081 gaatctgtaa tgcagatttg tgaattgatt ttaaaagttt cgtgggaggt taatgaactt 160141 tatgtacagt tcttagacag aaaggtctgg caattagaca tgatttttgt gaaataggaa 160201 ctaatcaatc taaaattcaa aYgacctact caggtgcctt actactcgta acataaatgt 160261 taggcttaga gtaattcaag atagctgaaa tgctggaaat gtgaaagaat taacaagStg 160321 gggtttgggt gaaattaggt gctgttagag ctcaaagcta acaggttgcg gtgtcagtga 160381 gttttagtca aatgctccca gtctatttag cactggctca tacaaaggaa gtatactgta 160441 ctactagtag gaattRtaac aatggagaga tggcaggtac cttaaaaatc taggattgca 160501 atttgcatag agtaattcag tgcaagattg tatggtagac actgttgatg ttggggagat 160561 gatctgacag aaaggaaatt attttaaaga tttcaggcgt aagacttttt tttatgctta 160621 atggttgatt cttgagcaaa tatgttttcc cttccttcta gagttctgag gaaacagaca 160681 taacatttgc ctgtataaac aaattctttg aatttttaaa agatatctgt ctctagttca 160741 gaagggtctc tttgggattg ctgtgttttt aactatctct gttttcaggg acttaatgat 160801 cctagagatc tgcaagcatt gtctgagctg agggaaaatt gtaaacatca ggcactttgg 160861 ttaatagttg aaagacctgt tgtaacccaa cagagaataa ggtagaagtc attcctaatt 160921 ggcctgatgg gtgagacagg agagtgaatt ctcatgcagc ttagcagtca gcataggtat 160981 tgaaagacaa gcccctgggg aagcaagaga ggaaccaagg gcttttgttg tatgtctcat 161041 caaacctctt aggagaaaga agagggaaat tgagatattg agaaaccaaa caagtagtgt 161101 tacaaatgag gcctactggg agtcccaaag gaagccagat tcctaatgag aaagcaatgg 161161 tctaggttaa acagtgactt ttttattaaa aaaagttatt ttttttttac tacttgttct 161221 tgagaaagtt tcatggctaa gtgctggaga gttgagggca cctggaactg tgcccaaagc 161281 agagcataaa ggattattaa attaaaagaa tgtgtatcat ctcagtgaaa cagaagggat 161341 gaaataacag accaccaata tttagagctg ggcaaagaga gaagtgaaga acagaggaga 161401 gattgtctag agaggtggcg agaaaaccag caaagtacca aggaagaaag agagtttcaa 161461 agagcatgga cgatgatgtc agatattcag aaaagtcaaa tcaatgaatc ctgaaagtaa 161521 tttattacat tttacaacta ggaaggtttt tttttttttt aagaatgtta agggactggt 161581 ggggatggat actaattatt ttgtgttgaa Ragagaatgg gggatgaaaa aatgtagggt 161641 aaaatacata taagctactc tttttagcag tgaggcaggg aaagaaaaga gaactagaag 161701 aaaggggaga agtgttttgt gttgtttcag ttttaaacta aatggggaat aatcgagtat 161761 gtatatagac tatgacaaag gagtcagtag aaagagaaaa agttattaag gaaacacttg 161821 aagtatattc ttgatggaga aatctgagga gctctatttt ctctgtcact tgaactttat 161881 ttcatatgct ccatgtaatt ggtcttcctg tttctttttc taataatgtg tagatatgaa 161941 atagctcttt ttattgtcgg cttcatctca tttaggatct agacgtataa gaaaattatc 162001 cttcttaaat atcttttatt tttattcatg ttcttttgaa attcaggtac atcatggaac 162061 tctctgtgta gcacatttgt ttttcttctt tgctccattt tcttcattga tactagttgt 162121 gatttttttt aatgacatct ctttttttgt gaattttctt ccttgatacc acttctctct 162181 ttgtaattta gaSttatgaa ataaagctac tatttattga acactccatt tttttcacct 162241 gtgaaaacag ggttaataat agaattgatt tcatacagct gtgaagaatg tatgtaagca 162301 aatacattta gtgtttagaa cattgtctca cataaatgtt caatgaatat cagctacttc 162361 tttttcgttt cttataacaa tcctagaaga gatttgagat aatacaattt cccttatttt 162421 acgggtgaag aaactgagac ccataaagtt tgagtaattt gcctacaatc acacagctaa 162481 gttccagggc cagaattcag atccagttag tccaactcca gagctgagtt cttaactttt 162541 accatttttt gtaaaacttc aaaatctgct ttcttgaaat ctattcttac cctacccttc 162601 tgtcatgcca tgactatgcc aattgtaagg tccagggtca ggtttgagcc ccagccgagg 162661 tccgagggga gtgggtagat gggcagatag ctgaaagaac actcgggggg ccataggcag 162721 gggaatatgg ttttattcag cagctctctc atcaacagct ctctcacact gtccgccttt 162781 atcttggttg tctgctccgg ctccacagct cctctcagca gccagctctg ccgctctggc 162841 tgctcccaca cacagctgca cggccagctc tcccttgcct gcagtgtcag cagcttaact 162901 ccttccctct gggcatgagt gtgagccatg tcgagccatg tagtaccctg gctcccctct 162961 gtccatctgc aagatggaca actccggtac tctctttttc tctaggtgca atagccaagc 163021 catgccatgc catactgacc catgctaaac caagcccccc atgcacagtg tcagcagggc 163081 aattatacct ttaacagaca ataaataatg gcttacagcc aagtatgaac ttacacaaac 163141 aggttattta acaagtggag tatgtgcctg catcctaaac tcactgagtc atgcaggcct 163201 ggatgtctgc cttggcctat ttcttgacca aagcacatcc atgtacctta taccttcctt 163261 gttaataatt aactgtaggg tacatagcca atttcttgca taattctctt attttccctc 163321 tgtatccatg ctgttttttc tctctagtca tttattatta atattctcca ctgttctagt 163381 caattccaca gtgaaatcat agctattttc cccccttgtt tcacctaagt gatttgtgag 163441 ttttggtata gtaggtgcct gcatgaaata gagcgctcac tgctcacctt ccctttctat 163501 cagatagatt tattttggac aaggttttct attcctttgc tgccttctca tgtggacttc 163561 agcccaagat ttgatgggct ccatttctct tactaccttt ttattcattg ccatataagc 163621 atatgacaaa cataactcct gactcgccag cacctttcaa cccttttatt cttctcacaa 163681 ataacatagg aactaatatt atagtaagaa ctatacctga aaaaataaaa ttttttctaa 163741 tacgtttttg agtaaatcag aatctgagcc ctcttgagcc tccacctgag gtatatcccc 163801 agctcttgct gtgaatgtag ttaagttttc aaaattgagt tggggagaca ttgattctct 163861 caacctgttg tgtcctttga aactcttgcc aatttttcat tatctttgtt ctcatgtttt 163g21 tagtcacttc cttgtacatt catatctacg taggtatatt tatattgttt acacgtattt 163981 attcacataa actgtcagat acaactttct taaattgcta atcactgttg tgatgattga 164041 tgtgacctag actaacttac cattgaccct ctgttaaaaa agggctcgtt taattagtaa 164101 gacctggaga gaaccactgt atttaaggtt atttcatcca ataaacgtgg ttttgtagag 164161 gatgtttata gttgtaaatg taattattgt agctggcgca gccagatctc tatttagaga 164221 taatattagg agacacttaa tgatcagcat gtatagttat gtttctcttt ctacttttca 164281 aaaacttttc ctggatttat atatatttgt gcacatgtgt gtgagtgtgg gtgtgtgtat 164341 attacaaaga aagttcagag aggtagcagc gattattttt gaaagttgga gaaagcagag 164401 ttggcaggat gaatgatggc cctgtgttta cgtatgtcat tggtaacagc tgcactgaaa 164461 agttgggcgt ctcagtttct catctgccac tttcttactg tacttcagag ttggagccat 164521 tccattatct gaaatgagtg aattgtcctc ttttttcgaa tatccgatat aatttgtatt 164581 ttctttttag tcactcaaaa ttggtgattt ttatagtata ccgattggat gcatatttga 164641 caactaagca attgtgttct ctcacttaga ttcaaaatct gtgagttcag ctgactaatt 164701 agtggtctgg atttttaaaa tcatggtaaa acgaagacaa taaatgatat gtttccttta 164761 aaaatttgtg tatttgaaaa caaagataaa atgaaaggta atcctatgta ttataagcag 164821 actaagttgc ttatctacca tggacacagg acattacttt tatagtgtcg atttttgata 164881 gtaattttta tatagctaca ttccaggctt ttttgaacaa aagagttaat gttaagaggc 164941 aaatggtaga cagttactaa tcagtgatta aaacctttgt ttgcagatat tttacataca 165001 aaaatttaga catttatatt caatttacct aatttacaga tatgctactc ttaaaacact 165061 tctttttata agctaatata ttatacaagc caaagtccta tttattttct gggctagcat 165121 ttgtatctaa ggtgctatta tggaaggatg actactgatt tcccatctgt ttcagttgga 165181 gaagagtcat gccaattgta ttcattgctc attttgggtg aaaactgagc acatatctaa 165241 ctgcttttga gtatatgttg cccctgaagc taggtagttt attcttctaa cactcatttt 165301 caacttaagt gaaaagcata tcagaatgct ttttattagt gactgtaagg attgacacac 165361 acacaaagga gaaacattta ggaaagctga cttctgtgat ttctttctct tttctttctt 165421 tttttttttg actgagccct cattctgtca cgcaggctgg aatacattgg caccatctca 165481 gctcactgca acctccgcct cctgggttta agcgattctc ctgcctcagc ctcccgagta 165541 gctggaatta caggcatgtg ccaccacacc tagctaattt ttgtattttt agtagagacg 165601 gggttttgct atgttggcca ggctggtctt ggactcctga cctcaggcga tccatccacc 165661 ttggcctccc aaagtgctgg gattacaggc atgatcctct gcgcctggct gacttaggtg 165721 attgcttact tattttatga atggtcctat gaacagagaa agctgatgta atctgtcctt 165781 tgtagttgtt tgctgtttta gtcctcattt gagatagttg gacttcattc acttctgaag 165841 tgtttattga agccaacttg tgtgaaaggc atctatccaa ggaaaagcca tataaacatg 165901 aattttcctc aaagtggcca aattcttttt tctcacgtaa aaggaaatta gattttttta 165961 ttagatgcta gatttggtag ctgaggttta acattactga atcgcttctt ggttaagacc 166021 ttgccagttg gccttacttt gtagcactaa acgcagcaaa gcagattgct ctatagaaaa 166081 gggatgctaa tgtcctgttt gatggtgatg aacacacatg taattgcttg taaagccctg 166141 aaagtagctt agatgttttt aacaaattgt gtattcaggt tttcaaataa ttacaatgaa 166201 gatttgctac cagattttgt agtatgtatg tataactata atagtgaagt cttggtcttg 166261 gaattctaac tttttagtat acttatcttt taagtatatt aacgttatag tctgttctga 166321 ggtttatgta gtggacttaa aaactcagtt aattgacctt tattgggtag gattaaaaat 166381 gtatttttaa cttctttagg tgaacattgt tgattgttag cttttacttc actggttctt 166441 aattatcttc attcaaagct ctactttaaa aaatgtagta atacaaacgt ggattgatgt 166501 ccagcaagat caaatatcac attacttaac tggattaatt ttgcagcaga cccagcatcc 166561 acatccctct ggagtctgct gtctttcccc atatccttac tgcttccttt gtttctgctc 166621 tccaggcttt aaatgtgctt tgctgcctca cttctgcaac tttgttcatg atagacccct 166681 tcacgcttaa gtgacttgtg tctccttttg acatgcctac aactgatccc atcttcaagg 166741 tttaactcaa gccccatcta taccaggaaa cttttctgac ttctgacaag actatctcca 166801 tgaccaaact ttgtcaggct cctccaggcc ctcttcttaa gtaggcgtca cccttggccc 166861 ccatccttga cagcgctgca cagaccagtt ttagcaagag tcttgcttag tcagtctaga 166921 gagaatcccc tcaccctgat gtctgatcac cctgcctgcc tcagtaagaa tcatgttatg 166981 tccgcttagc aagaattcct tctagccttg atgtctcctg ttagtaattt tccatccacc 167041 aatcccccag cctgcttctg tctataagtc ctcacttgtt ctttgtatcc tgagttgacc 167101 ctaatctttc tttccccatg caattgtctt gacacctatc acaatagtct tttttactat 167161 ttaaacaagg atcggaataa ttttttcttt aacWcttctt gcatgattca gttactgcct 167221 tgcttggtat ctcttttagt tcctcatata tatgaactta ttcttcagta cctgttgaaa 167281 tgttacagct tcttttctcc cagagtttgg cgagcaggag ggagtgttac agctatttta 167341 ctctcacagt ttggtgagtt ctgagttctt gtcttatgac caaaaggaat gaggtacaca 167401 gacactggag aatgagtaag tcagagtaga attttattga gcaacagaag gaaagctctc 167461 agcagcgaga ggggacccaa aaatgggttg ctggctgcaa gcctgagtct ggggttttta 167521 tgggcttaga atggtcaaat atgtgctgat tggtttatgg ataggcttga gaagatcacc 167581 attcagaaag agagatgata gtgtaaagaa ccaattgggg gctgaagtga aggcttggcc 167641 tgggaccaat caggagctga agtgaagcct tggcctggga ccaatcaggg gccaagtgta 167701 ctgaacgaga atggacattg tcactctggt cactggactc catctggaac tgatagtttg 167761 gtgttcagac ttcaaaatgt ccttggcttg aaggtcgagt ttcactggga acccgttcct 167821 gtctgcctag gaatttgtct gcctcctatt gctatcaaca gtactgtaaa tagatgctca 167881 gttaataaat gttacctgtg taatgattgg aaaatgtttt ggaacattcc aatcaggcta 167941 aggttgatga gacaagacta acagatggac ttttgggata gagatttgtt gtcaggacat 168001 ggagggtctt caactgaaca tttggatata gtctctgtac ctgggttcat agagtaacat 168061 ctgctagcag aattctcctg aagatgattt gattggttgt tttctgtcac tgtaaataga 168121 gcactcccac tgaactgaat tccagccagg taggttctgc ctccatgtgc ctgccaggcc 168181 tctacactgc tttctcactc agtcttctgt tgcctagcta gcaagattgc tttcaccaat 168241 aaatcaaaat gcaggagcca tgaaacatta tgaaagaaat aagtgttggg atcattttcc 168301 ttacaaggaa ggtgtgtgct tattggaact tgaggcttcc tgggtgatat ggtttggctg 168361 tgtgttccca cccaaattta atgttgaatt gtaactccca atgtttgggg agggaccttg 168421 tgggaggcga ttggatcatg taggcagatt tccccgttgc tgttctcatg atagtgagtg 168481 agtctcagga gatctggttg ttttgaaagt gagtagcact tccccctttg ctctctcttc 168541 ctcttgctcc accaagtgag gaacgtgctt gcttcccctt cgcccttctg ccatgattgt 168601 aagtttcttg aggcctcccc aaccgtgttt cctgaacagc ctgtggaact gtgagtcaat 168661 taaacctctt ttcttataaa caaccgagtt tcagatatgt ctttatagca tgcaagaaca 168721 gactaataca ctgggtttct acttaagccc atccactaaa aggatatatt attaaaccac 168781 agcgaaatag atgaccaatt attaaagttc tgtagaatgt tgttcttggg aaaaatttac 168841 atatgaaaaa aacctaggaa atagacacac atgttgaaga atttaactct gaatagtaag 168901 attactattg gtgaaaaatt tttctgtact gaccaagtat tctgccataa acatgtatca 168961 atcagtgtta taattaggat aggacttatt aatgtcattc taaaatatat tggtttattt 169021 tgacgtttgt aaagaatgat tagttgaaaa cctccaagaa taatgacact actttcagat 169081 taaataattt gatcatgagt gtcttgaaag aaaaaacagt tataagcaga gtacttttga 169141 tgaacaaagg agtagtataa gagtgtggac tacacacctt tcttctgtgg ttcatgcttt 169201 aattattgca accccacaga taacttagga agtctgacca cctagatcca aattgtgaac 169261 ctgcctcttc tagttgtgtg acttacaaca aattatttag ctaccctgtg tctcagtttc 169321 tttataaagt gaagacagtg gtagtatcta tcacacagag gtattagcgt gattaaatga 169381 gacaatgtaa ataaagtcct tggcccaggg cctgccgcat agtggatacc tgaacatcag 169441 tgctagtttt gcttttactt tatttttaga gacagggttt cactctgtca cctattctag 169501 agtgcagtgg caaaattata gctcactaca gccttgaact cttggactca agtgatcctc 169561 ctgcctcagc ttcccaacta gctgaaatta aaggtgtgag ccacctcgcc tggctctatt 169621 tttgaattaa agactgttat cttgatttta aatttattga ctgtgtataa aaccagttca 169681 ttcaaaatca ggctgatttg tactctggct tgcttggtag gttttagaag taacactggc 169741 ataggtcttc tcttctcttc tctcctctgg cataggtctt ctcttccctc ctctcctctc 169801 ctctcctctc ctctcctctc ctctcctctc ctctcctctt ttctttcttt tttttttttt 169861 tttttgagat ggagtcttgc tctgttgccc aggttggagt gcagttgtgc gatcccagct 169921 cactgcaata tccatctcct gtgttcaaat gattctcctg ccccagactc cagagtagct 169981 ggaattacag gcgcttgcca ccatgcctgg ctaatttttg tatttttagt agagatgggg 170041 tttcaccatg ttagccaggc tggtcacgaa ctcctgacct caagtgatct gcctgccctg 170101 gcctcccaga gtgctgagat tacaggtgtg agccactacg ccaggccagc acaggtcttt 170161 cttataccag ttatatataa cgcttagaat ttgttctttt taaaatctat ttagctcttc 170221 agttatatat gaagtaatat aaaacctgat cttcaacatg tgtaggtagt tctttttcaa 170281 ctttatattt aattgaataa ctttttaact tgataatggt cttgcctata agacagttca 170341 ttttgagtga cacccttatt tttagaacag acctttagat tcaggtaatc agtgatgcca 170401 tatagcattg ttctctaatc cttttttgtc ataaaagcct taaagtaaat aattttggct 170461 tttcttgata ttatttttaa tttcattttg aatatattca atggtaacat ttcctataag 170521 tatgcaagta atacattttt attggggaaa ataaaaatca ctcataatcc tcttgtctta 170581 atatctctct attactttca ccaggctact gtgaaatttt ctttctttat tctccaaggg 170641 cctttgcagg caaccagaaa aagaaaatac tcgcttaaaa ttgtggttat aacttaaact 170701 tcaggggtgt gtatgtgtgt tttggtctct attagaatgg gtggagaaga gtctgaactc 170761 tgaatacccc tgccttaatg accctcgagg gctgttttaa ttgtttctcc tgctgttcta 170821 agcttcactt aatttcatat gactattttt gaatgcgaca tgcaaaatct ctagttaata 170881 ctatttggca atgagtagta cttggggact cctcagagcc tcatggtggt gaatcagtga 170941 tgtgattttt ttggtgcatc tcatttcact gctttggaga tgcttttttc atgagagtgg 171001 aaacttgact tttcttgtgt gatcctgggt gtgtatgcct ctgttagaga aagagggggc 171061 atttatgact ctgctcaaga aacagaaaca gaatgcttta aacacatctt tggaccaaga 171121 ggcttgaaat gctgtaaagt tgagcatctg atttatctgc ttttctttaa tcctagctca 171181 tgcaatgatt cattctcatc gcgatgctgt atatggcttt taaaacagaa gatKaggaat 171241 gaatgggttt gactttgatt tttagataca gtatgatatg tagtatgtaa gaattagcaa 171301 gagtKtaata agtaatcaaa gaYtgaggaa aagtgataat atcaagaagt atatccattt 171361 cttttctgct tttctaaaac agtttctgtg ggaaaaaaaa gctactacag ataaaaatct 171421 atttgaaatg gcaacttgac ctcagaatga gaaaatttga tttctctaga aatgtgaaat 171481 acaggttttt caaagacctc agtaatgtgt ttctccagac aagtgtgctt gaaagtagga 171541 ccagagaaaa acgaaaatac ctcctcctcc ccctccccct tcccctcccc cttcccctcc 171601 ccctttctcc tcctcctctt ctcattttcc ttctcctcct cctctccttt tccttctcct 171661 cctcctctcc tctcctcctc ttctccttct cctcttcctc ctcctctttc tcccccccac 171721 ccttctccta cctggcttcc tccttcccct tttcttcctt cttagttttt gttatttggt 171781 gtttgtttgc cttcacagaa ttcctttctt catagttttc agtgtatgtg ggtattatat 171841 ggtacatgtg gcattatatg gtacatgtgg gtattatgtt tatgtataaa aactcataga 171901 gaacKaatta acatagtagg tttcaaatct cagtatgtgt gaaaaatcaa tctgaaaaac 171961 tcataaggat ctacatttac ttatttttta tgaaactatc ccatctcatc aaacacggcc 172021 cttctctagt aatttcaaga gtatgtgtaa acaactactt tttacctctg tggatgactt 172081 ggagattttt cctgtgcttt gccttctttt gatgtgtttg gagttcttcc attcctggtc 172141 cttgataact ttgccttact tttgtttaga atttttcctt ctttcatcat tcattttggt 172201 tgcttggtac tttcctgtct tctctgttag ctggtaatct cctcaagggc tgtatgcatg 172261 ttatttcttg ctccacctgg aacaattcct tgcatctagg aagtatttct cttcaaagtc 172321 ctgagaagta tacaacccat agccctaaaa ctccagaagg ttaatgtatt aaaatggatg 172381 attaaagtct ctcaaaaccg aacaatcaaa catcaaagca gataagcaca agtcatctca 172441 atgagagaag tggaagaatt agRaaccgag tgtgagctcg gctttaaagt tcacacacac 172501 aggggtcatg gggatagaaa ggtcacagaa gaagtgcaag cactcacctc ctgatatcat 172561 tgtttccagg gagagttagt ttcaggcatg aaagtgcaga acaaatgtag atgtgaatta 172621 aattaacaaa tgtcttagga catttgatag tactttggtt ctctttggag ttctgattga 172681 agacttgaga tgactgttgc acagaatttt aaagaaattt ggagttgaaa ctgtttcatc 172741 actgtccgtg atctttgagg atctatgaaa aattggagag gcattagcag tcttgagatg 172801 tccaaacctt tacagaagac gataaatcta tgaaccagaa ccgaaggaaa tggtgtgaca 172861 ttccccttgc acgctcttct tgttccccct tctctaatga aaatactgtt ccgatggttt 172921 ctcaacaatt agaaagcaaa atagtgacac gaagttagtt aaaaaaaaaa aaaaagtcat 172981 acttaaataa ccttaattcc ttgtttggat cagattttta agctagtaga cttgcagaac 173041 actgtagcta ttatatatct gcttatttta aaaatgttgc taaatgttcc cagttatgtt 173101 ctggtagata agaggatcat aggcagttgg atgatgtgct gttgctggtg gtggatctaa 173161 aacaggctgt tcagctatac ctgagagtag taagttttcc agtaaggtgc tgtttcagta 173,221 tctcttttac gtggtaagga cttggctcat ttgtttacca ctgagctttc aactatgagg 173281 acactcaaaa tagttgaaaa acttttgaat gtttatagta aaaaggcgac ttcagttttg 173341 gagagaccag gcaaaggaag agaggcagtg agaagctggt gttggaacct gaaggtttaa 173401 cacaatgatt ttcagtcctg gttgcacgtt agaatcactg cgggtgtttt tacaaataca 173461 gatgctagga ctttacccca caccagttaa atcaggggca gagctaggca ttgttgtttc 173521 aaatctcctc tggtgattct gatatgtagc caaggttgag gacctgtacc ttgtcatctg 173581 tgcagctgca aaagctcggc ccatccctct ccatgctttg cctagtgcac ataggggcag 173641 ctgtgccgag cagcagccaa aacagtagcc tctattccac tgcttccaag agactgccag 173701 gatggaatcc tctgtgcctc acatcactgt gtcatatccc aggcactatc caaagtaaaa 173761 aaactccctg atcatccact atgcctcaga ctgcaccctc atatttcttc ttcccttttg 173821 tttttaacca tttgcaagta tcatgtttct taatgtgtgc cccacactgt ccctttcctc 173881 catcctttag gctctttcca tgtgttctag atatagaaca tcattctctg atcaggaaat 173941 tcctacatat tttctacctc ttctctgagt gtttacttct gctttaacag aaaactggct 174001 gtctcttgca gtcccccaag taactcataa atttatatgt ctggcctaga tttttctact 174061 gagatccaga ctcataaata ccaatgcttc ctttatgtct ccagttggat gttcccagac 174121 taagatcttt ttcccaaaca gaactcttga tacattttgt ctaaatcttt catcctttaa 174181 tttcactcat ttcagtaaat gatacctaca tccacttaga tgctaaaatc aggaagtaat 174241 ggagtcatcc tttataattt ccgtatccca attcagttta tcctaacagc ctgtttgttc 174301 tgtcttcaaa ataccatttt ccttttttcc cattgctctt accagtaccc tggtgagaat 174361 agccaccaag tttcacccag agccccacaa cagctttctg actgcccttc cggctcccac 174421 tgtgtgctcc tgcaggaatt ctccacacca tagcgagtga gctgcagaca cagaagttaa 174481 tcatgctgtt acccttctta agatctttca gtgttttttg tatcagtcct ttatgcagcc 174541 cagaaggccc ttcgtgatct ggctcctgtc ctctctagct cttccaccca cacctcacta 174601 gctctatcct tcttccccca ttttttcttt cccttcctcc ttctcttctt tatttttgtt 174661 taacacatca cattctcacc ctctgagctt ttgtgcaggt tgttccatct gcctggaatg 174721 ttcttggttt attcttttat cttccttttt tcagcttaat cctttcctgt ggaatgtaaa 174781 aattgaccga ccttccttcc ttccttcctt ccttccttcc ttccttcctt ccttccttcc 174841 ttcttttctc tctcctctct cttttctctc tttcttttct ttctctcttc ttttctcttt 174901 tttaagacat gggcaactgg acacggtggc tcacgtctgt aatcccagca ctttggtagg 174961 ccgaggggtg gatcatagtg agttcaggtg ttcgagacca gcctggccaa catggtgaaa 175021 ccccgtctct actacagata caaaaaatta gctgggcgtg gtggtgcata cctgtaatct 175081 cagttactcg ggaggctgag gcaggagaat tgcttgaacc caggaggcag aggttgcagt 175141 gagccgagat tgcgccattg tactccagcc tgggcaacag ggtgagactc cgtctcaaaa 175201 aaagaaaaaa atataaaaag atgtgcatgc tgtgttgcct aggctgaagt gcgtggtaca 175261 atcatagctt gctataacct tgaactcttg ggctctagtg gttccccgac ctcagcatcc 175321 taagtagctg ggactacagg cacgtgccac catgctcaac tattttttaa atttttgtag 175381 ggagaaggga ttttgctgtg tggcccaggc atgtctcaaa cccctggtca gaagtgatct 175441 tcctgcccca gcctccctat ttcttttata tagcgtgctg agattttccc ttatcacatt 175501 tataccaatg catattgtat tctttaaaaa agaacttatt atagaaaata actagtagag 175561 agcatagtca taaacttcca tgaagccatc acccatcttc aaacatgggc aactcatgac 175621 tgatcatatt tcatctatat tcattccctg caattatttt gaaagaaaac cccggacctt 175681 atattacttt atattagatt tattttttga aagataagca ttgtgtttta aaacacatga 175741 caatactata tgataacatg taaaaagtta aatgttcctt aatatcaact atacagtatt 175801 aaaatacact ttgtttgaat ccagaaaaat tgagtctata cattgcaatg aattgcagtt 175861 acatgtcaat cttttagtcc atgggttacc cctaccatgc cttttttccc cttgaagttg 175921 atttgttgaa gaaacagatt aatttctcct atagagcttt agaagtctgg attttcctta 175981 ttgtttccta atggtgttat ttaacttgtt cccttatgcc ttttaaataa gtagttagat 176041 ttagacttgg tcagaatcta actgttgata atctactaag tgattatggt tagcaaaatg 176101 gtgatattca aattctgtct ttccgtcttc atttgttaca tgcagtgcat ctatagagaa 176161 acttcctcaa atcaactaca atatttaatt atactgaggt acagtgtata tgaaagggta 176221 tgaaagggaa ggaaaatgtt tgatatattc tgtatttaga aagttttaaa gtaatgaaat 176281 gattctgtaa taccctccaa aatgaccaat taggtttttt atttcatttt aaaacttata 176341 aatttattta tttattttta tttttatttt attttattat tattatactt taagttttag 176401 ggtacatgtg cacaatgtgc aggttagtta catatgtata catgtgccat gttggtatgc 176461 tgcacccatt aactcgtcat ttagtattag gtatatctcc taaagctatc cctcccccct 176521 ccccccaccc cacaacattc cccagagtgt gatgttcccc ttcctgtgtc catgtgttct 176581 cattgttcaa tacggtgttt ggttttttgt tcttgcgata gttaatgaga atgatgattt 176641 ccaatttcat ccatgtccct acaaagaaca tgaactcatc attttatatg gctccatagt 176701 attccatggt gtatatgtgc cacattttct taatccagtc tatcattgtt ggacatttgg 176761 gttggttcca agtctttgct attgtgaata gtgccgcaat aaacatacgt gtgcatgtgt 176821 ctttatagta gcatgattta taatcctttg ggtatatacc cagtaatggg atggctgggt 176881 caaatggtat ttctagttct agatccctga ggaatcgcca cactgacttc cacaatggtt 176941 gaactagttt acagtcccac cagcagtgta aaagtgttcc tatttcccca catcctctcc 177001 agcacctgtt gtttcctgac tttttaatga tcgccattct aactggtgtg agatggtatc 177061 tcattgtggt tttgatttgt ggttttgatt tgcatttctc tgatagccag tgatagtgag 177121 cattttttca tgtgtttttt ggctgcataa atgtcttctt ttgagaagtg tctgttcatg 177181 tccttcgccc actttttgat ggggttgttc gtttttttct tataaatttg tttgagttca 177241 ttgtagattc tggatattag ccctttgtca gatgagtagg ttgcg'aaaat tttctcccat , 177301 tttatgggtt gcctgttcac tctgatggta gtttcttttg ctgtgcagaa gctctttagt ' 177361 ttaattagat cccatttgtc aattttgtct tttgttgcca ttgcttttgg tgttttagac 177421 atgaagtcct tgcccatgcc tatgtcctga atggtaatgc ctaggttttc ttctagggtt 177481 tttatggttt gaggtctaac atgtaagtct ttaatccatc ttgaattaat ttttgtataa 177541 ggtgtaagga aaggatccag tttcagcttt ctacatgtgg ctagccagtt ttcccagcac 177601 catgtattaa atagggaatc ctttccccat tgcttgtttt tctcaggttt gtcaaagatc 177661 agatagttgt agatatgcgg cattatttct gagggctctg ttctgttcca ttgatctata 177721 tctctgtttt ggtaccagta ccatgctgtt ttggttactg tagccttgta gtgtagtttg 177781 aagtcaggta gcatgatgcc tccagctttg ttcttttgtc ttaggattga cttggtgatg 177841 cgggctcttt tttggttcca tatgaacttt aaagtagttt tttccaattc tgtgcagaaa 177901 gtcattggta gcttgatggg aatggtattg aatctataaa ttaccttggg cagtatggcc 177961 attttcacga tattgattct tcttacccat gagcatggaa tattcttcca tttgtttgta 178021 tcctctttta tttcattgag cagtggtttg tagttctcct tgaagaggtc cttcacatcc 178081 cttgtaagtt ggattcctag gtattttatt ctctttgaag caattgtgaa tgggagttca 178141 ctcatgattt ggctctctgt ttgtctatta ttggtgtata agaatgcttg tgatttttgc 178201 acattgattt tatacctgag actttgctga agttgcttat cagcttaagg agattttggg 178261 ctgagacaat ggggttttct agatatacaa tcatgtcatc tgcaaacagg gacaatttga 178321 cttcctcttt tcctaattga atacccttta tttccttctc ctgcctaatt gccctggcca 178381 gaacttccaa aatttaaaca tactttatat ctttaaattg caggtattat tttactaatg 178441 cacaagttgt ctaatttgac aaatgggagc ctctggaatc tctttgacat gcctcagtcg 178501 tttttgtact tagatgttct gtgtctgttt ccttggctaa actattggct ccttaaatgg 178561 ggggacttgt ctatattgtt tatccttcac tccacacaca ggctcatagt ctctccatta 178621 atatttattg aataaggggt gggatattaa aatttcatta agtgaaaggc tgtcttatag 178681 aggaagacct agtttagtct ttgtggattc agatcttgaa tcagagagta aaactcacag 178741 gaagcatttt tgtctcaaca taaggaggaa ctaaataatt tgaattttta tagaggagtt 178801 ggggttccat gaaaatgttt tagggactac tttgatccag gcagtgagag tacaaggata 178861 gactatcaag ccagtgagga tctttttgtc tccttgggag cctggatgat tactgaggtt 178921 acttttaatt gcaagatgat aagaccctaa aatccttggt tgacagattt tatttttaga 178981 aaggtgcaaa tttgggtggt ttaaaattgc tgaaatgtac ataatttttt cctatgaact 179041 ttatatgcca ctctaatatt atgtttctaa atattatgag tttgtatatt tgataaagca 179101 ttgataatga ttaatcatgc tttagtagca atcaattctt tttataggta ataattgttg 179161 attgaatatg cccttccctc atttcattaa atctttttgc attgttagtc acatcctaat 179221 aaatagctgt tatactattg ttttattaat ctttgggttt tattcaaaaa gaaattaatg 179281 tgtccatttt tgctttggtt ggttgtactt ttgaggtttt actgaagaac tatttgccca 179341 accaatgttc tgaagcattt cccaatgttt tcttttagta gtaagcgtct acaagcaaac 179401 aatcaacaaa gtgaagagac agcctacaga atgggagaaa atacttgcaa actgttcagc 179461 agacaaggga ttaataacca gaatacataa ggaactcaaa caaatagcaa aaacaaaaat 179521 ccccccaaac ccctaaagat cgattaaaaa atgggcaaaa catttgaata gacatttctc 179581 aaaagaagag atatgcatgt tcaacaggtg tatgaaaaaa tgctcaacat cattaaaaat 179641 ctgagaaata caaatcaaaa ccatagtgag atatcatctc accccagtta aaatggcttt 179701 tatctgaaag acaggcaata acaaatagcg atgaggatat ggagaaaggg gaacacttgt 179761 atgctgttgg tgggaatgta aattagtaca gctgctatag agaatactgt ggaggagcgt 179821 caaaaaacta gaactaccat atcatccagc agtcccactc ctgggtgtat ctatccaaag 179881 gaaaggaaat caatatgtgg aagagatacc tgcaccccca tgtttattgc agcactgttc 179941 acaatagtca aggtatggaa tcagcttaca agtgtccgtc agtggatgaa tggatgagga 180001 aaatgtgata gatagtacac aatagaatat tattcagcca taaaaaataa ttagatattg 180061 tcacttgcaa catgggtgga acgggaggac attaacttcg taaataagcc aagcactaag 180121 acaaatagca catgttctca gtcatatatg ggaactaaaa aattgttctc atggaggtag 180181 agtagaatga tggttactgg aggttgacaa gggtcgtgga gagatggagg ataaagaggg 180241 gttgattaat aggcacaaaa acacagatag aaggaataag accatttggt agcacaatag 180301 gatgactata gttaacaata atttattgca tatttcaaaa tagctggagg agtggatatg 180361 gaaagttctc aacaaaaaga aatgataaat ggttgaggtg gtggatgcct caattaccat 180421 aatttgatca ttacacttta tatgtttata tcaatagcat atgtaccctg taaatatgta 180481 caactattat gtatccataa gtttttttaa aaagaaatta atttaagaca aactagtttt 180541 agtcttcttc cacttctctc tgtattactt tgatatagat tatgacaagg tgtaattact 180601 gacagtttac cttgaaattt taatttattt ttctggaata aagtattgta gttagcactt 180661 ttaggatatt cctgaagagt aaatgttaaa cagtgttgag atgacttctt attcacacct 180721 gaatcagaat tgaatttaga tgacagtaac aatgtcatga atatttagtt aagtttaatt 180781 tttgaaatat gtatgtaata cagtatagtg agcattttaa ctagcatata aagagggaat 180841 taataaatga aacactatta atataacttt aaaaatattt ttaataactt tgccaaaaat 180901 ctgtaaattc ttctgaaaat attgtccttR ccctactcca gcattctact gtcactccct 180961 ccaaagtatc tacatttcct tctattgctt ctagaccaat acYgcaagga aacgagcatt 181021 gtatatgtct gcacttggta ttattttcct tcgcagtttc tcttgagaca aaatcataat 181081 ggaagagaga agcagaatat attaaatttc ccagattata ttaaatttat tttgggtata 181141 ttgctttaat ttccttcata tcttgtagac ataatttctt ctaggtgtta gcacatggac 181201 actgttttca gagatgacac agataatatt tgtaattttg ttttcttgtg ctaagatagt 181261 ctattaattt gaagtaacta atggaataga agacctttag gctttctttg agaatttttt 181321 tccataagga agttctcttt aagcatcatc ttttgaaact ggaaaatgta ctttgagcta 181381 agtggggagt tttcctttat tgtttttgca gaacattaaa tgaacaaatg aatgggtgaa 181441 aaaataaata ggctgttttc tttattgata acttctctca gcactatggg aggccgagat 181501 gggcagatca cgaggtcagg agatggagac gatcctggct aacacggtga aaacccatct 181561 ctactaaaaa tacaaaaaaa attagctagg cgtggtggtg ggcgcctgta gtcccagcta 181621 ctcgggaggc tgaggcagga gaatggtgtg aacctgggag gtggagctta cagtgagctg 181681 agatcatgcc attgcacccc agcctgggcg gctgagtgag actccgtctc aaaaaaaaaa 181741 aaaaaaaaaa gagaaaactt ctagaccttg ctttactccc acaagaaaat tttatattta 181801 caaatttagg gcacacagat gtgtggacag agtttctgaa attgacagat ttggatttgt 181861 gctttgtgct tagaaacagt ttgaaagttg gatccccttt cagcctggct ctacctggct 181921 acccagtatc cccatgtcct gtgcatggag atattctccc cactcctgcc cagtgcagtt 181981 cttcctggta cggcactttg gagttcatgc cgcctgatgg gcagactaaa gcaatgagtc 182041 atggctcctt tgggctaagc tgggaatgac agttattgga aaaataagag aataagcata 182101 aagaatctct gaaataaaat ggctctctat acagcttaaa gcaactacag gcaaatttgg 182161 cagtaactgc aatagaacat tctgtggtaa tattagcaca atttagagcc ctttttattt 182221 acctgaatta acgtctccac tggcaatcaa gccctgattg ccttctattc attagccttt 182281 gatttaatta ataagacttg ttgaagaggg atcttcaatg tttttctgta aacagctcta 182341 atttattgat tcaatttgaa ttttgtgatt atttcaagtt atttaaatca acgtttgaat 182401 tatatgtttg aagttttcat aaaataggtt aaatccacaa gataattaga agacacaatg 182461 ttcattttgt ttttcataca gtaatatatc tttttgatat ctttaaaaat ttccattttg 182521 taaatgagtt agtaacttag actgtcaaat atttcaggtc atattaaact ttaaaataag 182581 gctggacaca gtggttcaca ccttaatccc agcactttag gagggtgagg caagaggatc 182641 acttgagccc aggagttcaa gactatcctg ggcaacatag tgagaccttt tctctaaaat 182701 tttttttttt aaattagcct gacgtgatgg catggctctg tagtctcagc tactctggag 182761 gctgaggtag gagaatctct tgagccccgg agatggaggc tggaggctgc agtgagccat 182821 gatcatgcca ctgcacttca gcctggacaa cagagtgaga ccctgtctcc aaaaaaaaaa 182881 aaaaaaaaag •gtttaaaata tacatgaaca aaaggtagac tattaaaaaa tttcttaacg 182941 ttattttttc cacagctgtc ttttctaaaa gtagacccag tgacttaaca tttttaccag 183001 gctttagaac tgagagactc agtagttgtt gagtgttgag acacgtagat aaaaagtaat 183061 taagaaagga gaaagtcaca atgactctta ggttaaagag caatttgata atcagtgtaa 183121 ttcttaatga gaaaccaatg aagcagtcgt agaaaaggga gatgctgatt agtggtcttt 183181 gctcagatta ttaaagatta gtaaggttag tgagtgtttt gaaacatgtc tgctggatgc 183241 aaaaaggtta attaacaaag cattctacaa attcttaagg aatataaaaa cttaaaggaa 183301 ataaaaactt ttctatatgt agatgcagta aacataaaga gaccacacct tttatttata 183361 aaaagaaaat aaacatttaa acctaacatg aaagatgttg aaaactttat aaaatgttgg 183421 tatttttgaa atttttggaa ataatacttt tagtaattta ttctggactt attttgcagg 183481 tatgatgagg aaaatgttag tatactatta taacagcatt aatattcacc cagtgaaatc 183541 tactctgtgc caagaaggtc ctagatactg agcacatatc agttgataaa acaggaaaag 183601 tccccttcat ttctggaact tatggtgtag tatatatttt aaggaaattt tagtttgaag 183661 tgatgtaata cataaaatct cagtgtcatg aactgttgag atgatcataa cttattaaaa 183721 acaaacactt ggaggttcaa ttcatggaga attcagaata tgaattccat gaacctaggt 183781 cttgtttttt tatgcagtta ccatagRaaa tattttcaaa gacctttttc actatgaaaa 183841 taatacaaat tagtcagtga aattacttag ggggaatcca tctttagttg cacttaaaaa 183901 atgagtgttg attcaattaa aggctggtgt cctttcagtg tgttacaagg caaacatagt 183961 ttcatgcctg agaatgtact tcaagtacac aacctacaga agcatgcggt tcctatattc 184021 cagaactcag ttcacaRtac gtgatatata aaagttaacg ctctcaagag aaRtggaaag 184081 ctctgcggga aaaaggttgt gtgtgtgttt tatgggtgag gggaaaatat ctgtaaatga 184141 ggggaaaatt ccaagcagtt cctggaatca gttactgcct cctcagggag ccagtgatga 184201 gctcaactgg gctgagaaaa attcatgcag tYatcagcac taactgcatc ccagcctcaa 184261 gccctgccaa agtgcttagt cctaaaagaY gaagtgaaga gtacaaggtg cagtctccag 184321 ctgaacccca tgtgcatagt aatttttttt gcctgcatct gggtacctag agcacaaaca 184381 ggattagaaa aatcaagaaa atatactcag gagaagaagt tgcagaacag aaaagcagca 184441 ggcctgtcct gtctgctaaa gcagaaggaa aaagaaacac aactcctgac cttgaggaga 184501 tggtacgttg tggagcctta taatcaggtc tccctatccc attactgtaa ccaataataa 184561 tgtatttccg caatcagttc aatgagaaat gccactagga tggttcaact atgatgaagt 184621 ccttgttctt ttgggtttta tgtctatggc agttttttga gcgaaagcag accaaataga 184681 tgtaggttta aaaaagagac attcaaattc tttcaaactc agacactgga ttctctggcc 184741 cacataagtt ctcctttgct agttctttaa cctctagaga tttttggtag ccatttaaat 184801 tgcaacaaga gaccattttt gacctattaa attggcaaaa tcagacactg agaacatata 184861 gtgtaggtga aggaggagag gcaggggagc tctatttggt ataggaaagg ataccaaata 184921 tttatattgg tatcctctat gtaggatgct tctccaatat tcatcagaat tggagatcag 184981 aaatgcacat acctttgacc ttgcaatggc acttttagga atttaactta cRgacatatt 185041 tttacaggat ggaattacac atacaagaat atttattaca tcattgtagt agcaaaattt 185101 gggaacaagc tacatagcta tcaacagagg actgggatta aacttagtat gctatactca 185161 tacataagaa caccctgtgg tttttgaaag caaaaggcag ttttctatga atttatgtca 185221 ccaaaatatg ttgttaagtg taaacaatat agagtgtact ctgtattgta taccactatt 185281 tgtgtatgtg tgtatattta tgtgtatata tatgtgtgat acatatatat gtaagtctat 185341 atatcttgta ccttttacat ttttaataca gttgtctctc catgtttgag gtttctgcat 185401 ctagattcaa ccaaatttgg attgaaaata attgggaaaa aagacataat ataacaatta 185461 aaatgatatg tgtaaaaaat acagtataac aactatttac atagtgttta tattgtatta 185521 ggtattataa gtactctaga gatgatttaa agtatatggg tggtgggcac aggttttatg 185581 caaacactac agcattttgt gtaatagact tacacatcct cagacttggt atcaaagggg 185641 atcctggaac caatccactg aggattatat gtgtgctttt gttttttcct attttaatta 185701 acaaacaaac caaataaagt atggttctag gcccagtgta ggtagaaaat agaacagtca 185761 aggaggggac taatatagat agttatgtct ttgattgatg gcagaaatga ctggataaaa 185821 agttaactcc atagcacaat cttactttta attggcgcca acacatattt agaatgtgtc 185881 tggaaggacc atctgctttg gataggtctt gtgtaatctt gtaatggtaa aatattcata 185941 acttttttga tgacatactg taatataaag cacaactaga ccaaatataa ttttaggagg 186001 ttgtagtaaa aaagaaaaaa aaacaaaaaa aggggaattt tttccttttt tttttttgag 186061 agagagagaa gaatgtcaag tttctgtcct tgggaattga atgacctcag ctaaagactg 186121 aaaatgaaga catttcagca gaaggaacaa agagggagct attggagaaa caaaggaaca 186181 gagttatttt tgattgcatg atttttaatt aatctgagac taattatcaa gtgtggtgat 186241 ttggttaaat actagtttca ttctggaagg aacacagtga atcacagaaa aattcagtta 186301 aatcttggcc tatgcaagta tgaatattta aaatgtgaat atttatgatg atgatacaga 186361 attcccagcc gaaaccttgc tttggtggta taattgaatc actgacattt ttagcataaa 186421 agtgaattta tttagttata taaattataa ggaagacaat tagaactata atgggcacat 186481 atttttatga attcacttat ctttcatttc tcacagggta aatgggaagt tggtagctct 186541 gaaggtgatc aggctgcagg aagaagaagg gacacctttc acagctatca gggaaggtag 186601 gcacttttcc ttgttgatat tgcttttgtg tttctatggt ccccgtagct attttaatat 186661 tatacacctc tgaatatgct gagttttaaa attacaggat tgtatctttc attaaaatgt 186721 gtaaactgaa atttaaaaat cagtatctct tgcagtcatg tcaaatcatg ttaaatgaaa 186781 caagattatc tgctgtgtgc tcagatgtgg aataaaatgc tgtgcattaa tggtgaagct 186841 atctaggtaa ctgaggaatt ttgtatgtct gctatcattt acagagttcc ttagatacat 186901 attagtttaa cattattccg tattgatgat ttttaaggaa aaatctttaa aaatggggat 186961 ttgtcatgcc atcttactag gcatttgaat ttcttttctt cctttgtttc tatcctttac 187021 tgtactttta ctggtttttc tgattggaag aagataacat agacattctt tatatattag 187081 ggtcatttat gttgtgatat tttcctctag tctgttattt tctaaaattt cttttataat 187141 gtagttattt gctacatata agattttatt ttttattaaa tcaaatagct ctatctttgc 187201 tttgttacct gcatagaaag gcttttgtat tccaagagaa taaaatatct ttttttttaa 187261 tcagtgggaa cttttcagtt cagtttaata agttttagga taagtaggtt tacctctact 187321 acatttttaa aagtgcagat tatcttgaca taagacttca gtttattttt gcattgaaag 187381 gatcacagct attattctct tcatccataa caagataaat tggtggtttg ctgcaataat 187441 ttatcaaggt attgatgaac taaatgtggt ctgtcactgc tttggtttgt ttcccacaac 187501 tgttgatatg atttacatgt acaactattg atatgattta catgtatcat ttttgaaaat 187561 cttgtttcta tttctactct ctcacctctt attctccttt tcattcaatt ttaattttgt 187621 ttccatcatt tatctttagc ggaaactgtt cttataaagt tcatcagtca cttgcttctt 187681 gtcaagtcaa atgtatacct ctctgtctta ttttacccag ccttttagca gattgcatgg 187741 ttgaaacggt ctcttctgtg acatcagatt ttccaagtag gtaggttttt ctcttaggct 187801 gaccttttct ctgagttagg gggagtttca ggacaggaaa gggcttcttt tttttttttt 187861 ttctgggaca gaatcttgct ctgtcaccca ggctggagtg caatggcaca atctcggctc 187921 actgcaacct ctgtctcccc ggttcaagca attctcctgc ctcagcctcc tgcatagctg 187981 ggattacagg cgtgcgccac tacgcctggc taatttttta tttttagtag agatggggtt 188041 tcaccgtgtt ggccaggctg gtctcgaact cttgaagtag tgatccactc acctcggcct 188101 cccaaagtgc tgggattaca ggcgtgagcc actgtgcctg cctttttttt tttttctttc 188161 taataagcac tctgtcctag gtgatattat ttatttcatg agtttaaaga gaagctataa 188221 gttgatatcc tacacatgca tctctttagc taagaccttg tcttcatctc catttcatat 188281 atccacctgc ctatttggca tcttctcttg aatacagtag tatataaaaa ggatactaca 188341 tcactaccaa ctgagattca tttcaggaat acaaggctag tttaatcttt aaaaatcaat 188401 cattgtatga cagtcatctc agacttaaca catctgaatg gaactcatga tcctcccact 188461 ataaatgaaa ccatgttctc cctgtattag taatagcagc atccagtgct tcctctaccc 188521 aaatctagcc atgaacaagc cctgttgatt acctctctaa atgatacctg aaatctgtcc 188581 acgttctgtc tctccactgc cacccctagt ccaggatacc atcagttctt ccatggactt 188641 ctgtaatagc ttcttaatta tacacctcac ttctcttgcc ttattactat cccttctcta 188701 ctctgttagc cgtataatat ttttgaaaac taaaatcata ttatgtcaat ccccttattt 188761 aaaattgctt caagtcctat atgactgatt ttcttcaaac atgctataga gtttcctgtc 188821 tcaggaattt tacacatgtt gttccccatg gctggaatgc tcttccctgg ctctttttag 188881 atttaggggt caattcaaac atcccatttc agagagagtt tctttgtcca tttatccaaa 188941 ttagtggctg accatcattt tatgcatctt tactctccac atcacaccct atttttattt 189001 ccattataat tcttattgga atgtgaaaat ttctttccac tctgtatata atcttagtga 189061 ggtcagagac cttgtctgat tgttcactgc tgtaccctca acatctagca tggtaatcac 189121 tctacaatag taagtgactt aaggaaaatc attaggttag aatctataaa tatgacagat 189181 tattagatac agtctgttcc ctcaaggaac ctgccttgca ggtgggaggt agaacatata 189241 aatcataagt tgaagaataa tatgtggtag catattaatg ccaaattatt tataaaagat 189301 tttgaaatct aaaagattgt gaaattattt ctaaaagatt gtgattttta aggaaattct 189361 tccattagtg atgggaggta aagtgttagc taggacttga attaggcata agatagaaaa 189421 acagtaaaga gtagattgag gagaagtgtt ccagacaggt atagaaaagg agctgagacc 189481 agaaagctca atgcctttgc caagtgcagt gaacaggagg aatagttaag atcaggagtt 189541 ctcaattgat agagtgggag ggatgggtaa ttattgctcc atggaagtgg cttttgtcat 189601 cacaataatt gaacaatgca accatgttta gtggatgaga gcttggcatt tacgtgagaa 189661 actcttaata cagagggagg caaactgtgg cttggggcct gctgtctgtt ttggtaaata 189721 aagttttatt tgaacgcagc actccaactc atttatgtat tgtctatggc tgctttcttg 189781 gagttgagta cttttgacaa actgtatggt cccccaaact taacagtata tgctatttgg 189841 ccctttcaat aaaagtttgt caRtctctgc tctaatacaa taaacaattg tctatcgggg 189901 gaaaccagcc cRcgatattc aacatgagtc cttttctatt tttcctaagt gtcggatggt 189961 ctgagaaata aagggaaaga gtacaaaaga gagaaatttt aaagctgggt gtccggggga 190021 gacatcacat gttggcaggt tccatgatgc cccctgagcc gtaaaaccag caagttttta 190081 ttagtgattt tcaaaagggg agggagtgta tgaataggat gtggatcaca gagatcacat 190141 gcttcacaag gtaataagat attacaaggc aaatggaggc agggcgagat cacaggaccg 190201 gggcgaaatt aaaattgcta atgaagtttc gggcacgcat tgtcattgat aacatcttat 190261 caggagacag tgtcggggag cagacaaccg gtctgaccaa aatttattag gcgggaattt 190321 cctcatccta ataagcctgc gagctctatg ggagaccagg gcttatttca tcccttgtct 190381 acaactgtaa aagacagata ttccctaggc ggccatttta gagacctccc cttggcaatg 190441 cattctcttt ctcagggatg ttctttgctg agaaaaagaa ttcagcgata tttctcctat 190501 ttgcttttga aagaagagca atatggctct gttctgcccg gctgtcaggc agccagacct 190561 aatagttatc tcccttgttc cctgaacatc gctgttatcc tgttcttttt tcaaggtgcc 190621 cagatttcat attgtttaaa caatttgtgc agttaacaca atcatcacag ggtcctgagg 190681 cgacattcat cctcagctta tgaagatgat gggattaaga gattaaagta aagacaggca 190741 taggaaatca caagagtatt gattggggaa gtgataagtg tccatgaaat cttcacaatt 190801 tatgttcaga gattgcagta aagacaggtg taagaaacta tacaagtatt aatttgggga 190861 actaataaat gtccatgaaa tcttcacaat ttatgttctt ctgccatggc ttcagccggt 190921 ccctctgttc agggtccctg gcttcctgca acagttgtct catgtcccac aagctttttt 190981 ttaatgtctt actgagcatt catgcaggtg aaaaatctgt ttatatttat gagcccaaac 191041 ccaactattt tgcatataaa caaaatatgc tgtgcacaga tttaatatat accaaactat 191101 ctaggaatac aactacagtg taaatcatgg aaaaattgta ttgtgttttg tttaaaactt 191161 tacaacttgt tcatattttg gaaaaattcc ttagtggcag tgctgcttgt gttatttaat 191221 tcaataatgc aatatcccac agtctgcatt tgtagtggtt gtgcttatgc tgattctgta 191281 catagatgtg agcaccactc ttcagtgtgt tccggtatag ttgtgtctac ttacatattt 191341 aaagactttg ttttattata aattaatttt tatttatttt ttgtattagt tacatataga 191401 tataaattaa tatatttgaa attatattta tatataaata tttgaaatta tgtatgtgta 191461 tcttgttata tatgaattcc atttcatagt agtaaaggca aaaaaagtag taaaatattt 191521 gttatataaa gagggtattg gctttgatgg gattgaaaat gactgaggta gaacaatagg 191581 tttttgttaa gctgtggagg gagataaggt taaaagtgct actgaattta attatacagt 191641 agaccctgaa tatgagagag gagagggaca gggactctgg gccaaaaagg aaccagaaga 191701 aaaatgaaac tggccagcag gcaggattcc tggtatgcag ggtgtgcact agaattaatc 191761 aacctaatct tactgttggt gctagtcttg gtccaaggtg acaagaaggt tcgtagtggt 191821 attgaaggac cagtgtgaca agcaggccca tcagtgggag gttcaaggga agaagcaagt 191881 aggatcacat tgaagttgtt gatgatcttc ttattcactt tggctgggtg tgaggcaagc 191941 tcctgaggca cattaaaggt tagcttctgg gaaacacaga gaagcgggga atgcaatgaa 192001 tccttagcac actgagacct ggctttgact ggcaacataa tttcatttta agccttgaga 192061 tgagcttagg aactggccct cagttgcggt tgtgttgtag aatgcagggc tgtgtaggtg 192121 ggatcttgtt ctgtgggtta gagagcctct gaagacttta gagttgggca tattagggac 192181 aaaaatctga tattcagata ggatatcaat tagaaaaaga agaaactgga agctgataag 192241 tcagtcattc agtgtgttgc agatttgaaa ttatgggttt attagatgtt agtaacaaaa 192301 aataatattc tatagaaaga gatgtcagag ctaggtgaag tattgattac agattgagag 192361 gaaaatgtca atggttttga gtttgactga gtgaaaaaat agggccagag atagaaatag 192421 ttggtgattg catggagaat tgcttttaag actttacagt ttaaaaggct gttatccgat 192481 ataatcttca tatgctagcc ctttgaaaaa gttttaaatt tttattttgt agaatttata 192541 ttgtttatag aacctgtatt ataaatatgg aattaaggct cagaggggtt agatgacttg 192601 tctaaggagc aggatcttgt acctagacct tgttagattt caacagggtc attactgaca 192661 ttttggagta atcaatttgg gttttaggga ttttgagctc atgagacatc tgtatgaaaa 192721 tgtcttgttg ggaatgtggg agtgcagctc acaagagttt agcgtaagta gtatatatgt 192781 accatggtcg ttaagaagtt gaaccatgta taacattttt gtggaagcga atgttgagtg 192841 aaaacagagt cagttacaag gcaaggtaga aactcccatg ggaagctgga ggtgatttct 192901 cttatgttgt acagtgatga aaaagtcaga atcaaaacct actgatttgt gtatgttgat 192961 tttgtattct gcaactttac tgaatcgaca tacacagatc agtaggtttt gatcctgact 193021 ttgtttttca tccatgtaca gtataagata agccacctca attagtttgc tagggctgct 193081 gaaaaaaagt accacagcct gggtagctta aacaacagaa acttaatgtc ttgcagtctt 193141 ggaagctgga agtctgagag taaggtgtca tggccctcca aatgagggca atgaggaaag 193201 atctgtgcca gccactctcc ttaacttgta gatagtggtc ttctccctgt gtcttcacat 193261 catttttcct gtgtacctgt ctgcatccaa attttctctt cttacaagga caataatcac 193321 tttggtttag ggtccaccca tatgacatca tttcaactta attacctttt tgaagaccct 193381 atctccaaat acagtcctat tctaaggtac taaaggtcag gacttcaaca tgaatttttt 193441 ggggggacac agttcagccc ataacagcac ttaatggctt tgggccttag taaccctacg 193501 tattaatcca ttcttgcact gttgtaaaga aatacctgag actgagtaat ttctaaagaa 193561 aagaggttta attggctcat ggttctgcag gctgtaccag aagcacagca tcttctggag 193621 aggcctcagg aaactttcaa tcatcctata aggcaaaggg gaagcaggca cgtcttacat 193681 gctgaagcag gaggaataga gagagggagg aggtcctata cactcttaaa caaccagatt 193741 tcatgacagc tcactgactc actattgata tgacaacacg aagggggatg gtgttaaacc 193801 atgataaacc accccagatc caatcacctc ccaccaggcc ccacctccaa taatggggat 193861 tacaattcaa catgagattt aggtgagggc acagactcaa accatgtcac cctacttgca 193921 aaaaatagga gttggattat gccatctctt aagaactact ttggcgttgt ggttttgatt 193981 tcccaaagaa tctttaaact cagaatttgg aatgttctgg agatcaggga atgatagaaa 194041 aatagttggg gccttgatca caaaatggca ttttattttc tattgaataa aatattttaa 194101 tgtctttcta ataaagtctg acttctgagt gatttttttt ttttttgtag cagtaaatga 194161 cttcaaggaa gagaaattaa actctgggtc agtttttgtt atttgttttt ttcttgcctt 194221 ctcattctgc ctttcatatt cttatttttc tgctgtttat atctggaagc aaaaggcatc 194281 atcattgctt agcctttccc cattaatact tctggaagtc cagacacaat aactcctctg 194341 tgtatctaat ggtagaattt gaaatattta gggcaatgtg ggagacattt gggatatgtt 194401 caattttaca ttgatgagga agcagcatgg tgtgttcaac tgagatagaa cacctgaatt 194461 tgaatttgcc cctcttctgc tgtgttgatc aatttctcat ttacaaaata tcaacagYgg 194521 gaagatttca gaataggaaa gcaccatgca cagtaaagta gtttgtaagt ggctacttgc 194581 cactcacagg cttacctaga aacttggatt ttagggcgta attttcacct caagtggaaa 194641 tacttgaagc aactctaatc taacctagat ttatgtccaa agatgtactt tgaattttat 194701 ctctcattga gctagagtgt gtaatggatt aattcaagtt caggcgcttt gaaactcatt 194761 ctgtcctcga tggcagcttg gagaaattaa gttgtagtgc tcaRggtcag cttttctatt 194821 ttaatttaga atcattatat ggcatcatct tggtttatga ggaacagata aagggctggg 194881 agatacagga gaggtttgaa agacagtggM taaaatgtct taggatattc catctttcaa 194941 acaactttta agtgttaagt gtgtatgttc ttactctctg atattgtatt ctagacttMc 195001 acgttttttg ttgtcttaag attttcttag acaggcatga ggtgaatgaa ccagttgtct 195061 cttttcatag attcttgaat atgtgatggt tttcttaggt gagaattatg cttaaagaga 195121 aatctagata ctctaatagg gaacaaattt aaattaaaat ggtagcagta taaatagaca 195181 atatttggtg tgtgcttgca cagccagagc ctagtctcac ttaacactca caaaaccctc 195241 taaggtaggt actatcatta ttgctatttt gaggttagta aagttaggat tggagaagtc 195301 actcacctaa ggttaacgct agcatgtggt agagctaaaa gctgaacctg gctgggtgcg 195361 gtggctcaca cctgtaatcc cagtactttg ggaggcggag gcaggcggat cacctgaggt 195421 caggagtttg agaccagcct gttcaacgtg gcaaaacccc gtgtctacta aaaatacaaa 195481 aaaattaacc aggtgtggtg gcgggcacct gtaatcccag ctactaggga ggctgaggca 195541 ggaaaatcac ttgaacctgg gaggcagagg ttgtagtgag acaagatcgc gccactgcgc 195601 tccagcctgg gtgacaagag tgaaactcca tctcaaaaaa aaaaaaaaaa aaaaaaaaaa 195661 agctgaacct gagcaatcat acggcagagc ctatacttaa acgttatact ctgctagatt 195721 ttatgtagaa attttgaatt tatgcttcat tttcatttca tacagagggt tgtgttattg 195781 ccattaagtc aaggttagca aaaaagatag ggattttgag gggggacatg ggaaaaaatt 195841 tatttataaa agtgataaca catttttcaa taaagaaagg aaggcagcat ccacatagga 195901 caagaaaggg tctaaaagag gaaaggaaca aatagattca acacaatata actcagagac 195961 agtagaaaca tgtagaggaa aaggggacct ctcatggtaa actctgtagt attgaacttt 196021 ttgtttgggt acattctttt taatacatgt ctgagtattc ccatgtgctt tatccacctt 196081 ctctctcttc ctttctccac ccttctttat gtattttttt cattattcat tctattagaa 196141 ttctatggaa acattttaga tttttaatac aaaatgtggt accaggaagg cagaggtaga 196201 tataaactga aaaagagata aaggaaaaag aacaacttct tttatttcaa atatttggaa 196261 ttagttaacc tgcttgtaaa atgaataatt ttatgattta attgtaaaat ttgtactgta 196321 taattaaaat attctaatag tacaataaat gttatatgaa ttattgatat tacttttaca 196381 aattttttaa agttataaat tggaaaataa gactgatttt aattgagtca ttaaaatttt 196441 ggtgtttgac tgatacttga ttctctacct tacatttttc ttttttaatg ttatagccta 196501 tctgtttttg ttgtttttca ttaaccatac catttttcct tgtaactgta tggtacaatt 196561 gcttgtgaag tttgtatatg taattgagtt ataattcaat tgataattaa ccagtctaga 196621 tttcatttct tgcatttcat gtttggggtg ttgtattgct tttctagggc ttctgtgata 196681 aattaccaca aatttgctgg cttattcttt tgtagtgctg gagagtagaa gtccaaaatc 196741 aggatattgg ccagttcatg cttcttttag aggctatagg gaagaaattc ttgctagttt 196801 tttcctagct cctggtggct tcctacaatc tttggtgttc tttggcttat cgttacatca 196861 cttcgatctc tgcctccatc ttcacatggt cttctctctc tctgtgtctt ctcctcttat 196921 agggacatca gtcattggat ttagagccca cgctaatcca gcatggcttc atcttaactt 196981 agctaattat gtctgcaaag gccccatttg caaataaggt caccttctga ggttctgggc 197041 tgacataaat ttctgagaga cactattcaa cctgctacca gtgtttattt ttctcagttt 197101 cacagggaga tttgtaggtc ataatggact gggacctgca ttggaccttt gaaagcttag 197161 gagaaaaatg tactacatgg tggttttgat aacactcttc tttgttttct tattactgaa 197221 gtttgcatat aatagacaat gaatgaatat agataacttt ctccaatgtg atttattttt 197281 gtttctctcc atataggctc ttttgttatt gttattcatt tatttttgtt ttcaagcaaa 197341 atatcattct ctgtggatta ttgaatgaca tatgaactgt ggcttgtgtg gagatagatt 197401 acatctgtca agttagtgag tatgattgag acattggtag ttagtctggg attggaagca 197461 ggaagaactg atataatgga gacctctaaa gctactaagt tgctgtgaaa tgataaaggt 197521 ctacttccac aattctatac gttggccact gggatttcag acacatttac acaaagacaa 197581 aatgttccag gctgttctgt tggagtcttt ttttattcag atatgccttt tatccaggta 197641 tatggacatg tttttttatc cagatacatc ttttttatct ttgagtagat tcctgggctg 197701 tcccataaga gccttttttt atccaaatat atagttttga tgatcaaata caacctaaat 197761 gataagtata taatcatctt tggttataac tgaaattatt ttgtcaatat ctggatgcct 197821 agatacttct tacccctatc accttcccag tggagagagg acatctgcca aaagagaact 197881 caggtcctct gttccctccc ttttccctga cctggagtct cttgcactca ggctcctgaa 197941 agctaagttg agagagtggg cacagatggg aagaggggct cctgggacat aacctccttc 198001 tttaatagac tggagggctg ttgcagggag aggaagaaag gacaaacatt tgtttccatt 198061 tgtgttttgt caatatcgct gtttggaatt gttcatcctc ttgtaatgat ttcaaaatta 198121 acaagttgat tatagatgga attttcagtg aaacattatg ttaatgcaac atttgaccct 198181 gtgtagtagg tgacaggtta aattaggttt cttcaagggt cttaataact ttttttaaga 198241 ctcaaaaatt ctttgctcag cctagacatt tctgaattca gctgttttat tggcaactgt 198301 ttttaaagac actatttgta gcatcattgt tggaagtaca tgaatcctat aaaagctaat 198361 taggaatcta aatcagactt Yagagattac cttgtccagg ggtttctcag ttgcatcctc 198421 atggtcttca agctatgtgt ttggtcttac agtaaatttt aataaatagt gaccagaaag 198481 tggtccaggg cctggtttct gaagcctgac tgcctggatt gcagtttgga cttcattctc 198541 atctaagtgt atgattttga gcaagtctta aacttgctgt gcctcatttt ccatttctta 198601 aagaggatga aaatacgact caactWacag gcttcttggg acattatatc catcaaatat 198661 gaacatgagg ccataaaata gaagcaatca aggaataatg aaaatttctt caaaataaaa 198721 atacattaac aggtattaaa ctttcagaag aacatttgga ttgtgaactc agagaaatct 198781 cccaaaagga gatcaagaag agttatcatc tcttatgtct ttgagaataa ataatatagt 198841 tatttgaatt ttcttctata ttgtcacttt catttatttc tgcttgtgtg tttggtctct 198901 ttcttattgg aagcatcttt cagctacctg gagatcttgt tgattgtcag ctcatattta 198961 aaagtcagac tttaatacgc tgtttggaag ctctgggtgc ttggataggg aatattggtt 199021 ggcagttttg tgatggggtg agttaaccat tttttttttt cttgcagtat ctaagatgtc 199081 agtatttggg ggtcgtttct tggaaggagg cttcagtttc tacagaaaag gattatttaa 199141 tctcctgcct ggaagatttc agtttgctgc ccacattgtg gggattgagt aagagacaga 199201 ggttacaggg gagtctcaac cttcaacatg cagattttta ttgaatttac ctattttcag 199261 ttcagattat gcagtgttag agagacaaaa aggcacccaa atatttaagg caaaaaatta 199321 atgggcctct aaaaaggttt tggcagtagg gatagatagg agataaatat gtttggaagg 199381 gacttaagag ggacacttgg tagggctttg tgtttgacta gacatggagc ttgatgaagg 199441 tggggttagt cagggtgact tccaggattc tggattgggt aattaggtag atagtggaac 199501 cagtaatgag taactgtggt tggggatagg ggaggcaggt ggagtataag aaagacaatg 199561 agttcaatta gtgagtttga aatctggcat tcatgtggca gttgtgtgac atggtggtgc 199621 agtttagata acaggtgttt gttgtatcta aattgagaac tttacaagtc atattcgagt 199681 atatgatcta gtttaatttt taattccttg aggaaggttg atgttaccat cttcatttta 199741 ctaatcaaga cactgaattc cttgagggag gttgatgtta ccatcttcat tttactaatc 199801 aagaggctga ggtctaacaa gatttttttt gtgcaaagtc atacaaataa ttaagtggta 199861 gatatggagt tcaccttgaa tattctaacc agggcctaga acagtgcctg gcacatgata 199921 ggcactcagg gtatgttgaa tgactgagtg aatgaatgaa taagctccca tgttctttct 199981 ttgtattcta ttatatggcc ttactattgg gacagaaacc catatgatga aaattgtaca 200041 cagattcttc tcaggcttcc ccagagcaaa aaggcgatat tgagaaagct ccataagcga 200101 ggagctggaa atttttcagt cttgatggag actgtgcccc tagctatgtg atcataagca 200161 agtacttaac atattttgtc tttagttttt tcatttttga aatggagacc atattatttt 200221 agagctttat aattaaaata atattaccaa catgaatctt ttacctggaa aaaagatcta 200281 taattgtatc actattattc tcaatgcata catgcagtaa tatgatgcac atttattggg 200341 ttaaaatatt ttttaaacct tctaacaatc accctttctg tctgtcactg aaaaaattaa 200401 catgaattgc ttaaagcgtt tttataattg acaggcaaaa attttgtaaa tggaagataa 200461 aaatccatga gtctagactg taattctaag tatgcttatg taaattgcca caattgttat 200521 tctaagtctg agtaatctga tgggtgtctg ccaactgata tcaacaaaaa cttgtcaagt 200581 gttaaatcat gattaaaaac tatgaaagtc atatgttttc ttttttatat taataatttt 200641 aaaggataaa gtttgttttt taaaatcaag taactgaatt cctggctgtt ttaaatttgt 200701 aaaaaattta tatgacattt tgtcctattt tgtcaactag aaatataaat tgagatatga 200761 tacttttata tttaagacat ttttaggagg attacataaa cagttctaat ctgaattcat 200821 gtataacttc taaaaatccc atggactttt tcagttccta ctttgccaat ctttaaaaaa 200881 cgctatcttg tttgattttc accaaatctt atgttatatg taggttttaa tatatccaag 200941 ttacaggtga ggaaattgag gcctagacat aaataaaatg tcctgtgtta caaaacttgc 201001 cagtaaatga ctgttaggat ttacactggg atttttaaat tgaggtgttt gttcaaagat 201061 aatacattct tccattcaaa atttctgggt taattttaaa aaatgatgag aattcgtaat 201121 gtacttgtaa acttcttgtc atgatagtaa ttaacatagc tactataagt tgctttaaaa 201181 aaatgtaacc catgagcaag gggggtatct taaagttcag tttgacatct caaaatcatt 201241 taatgtaata ccatgttaat agaataaagt ttaaaaatca cattattatt ccaatagatg 201301 taaaaaatgt tcgttacaaa agctaacacc tattcgtgtt aaaggcttaa caaactttga 201361 atagaaagga attttctcaa cacacacaca cacacacagc catatttgtg tatactagca 201421 atgaacatgt ggaaaacaaa atttagaata caataccact tataatcact ttaaatactt 201481 ataataaaaa agaaatacct agggataaat ctaacaaaac atatttagaa tttttgtact 201541 gaaaattaca aaatcttgat ggaaagaaat aaaggaagat taaaataaat aaaaagatgt 201601 accttgttta tggattgaag atctcgtatt gttaagatga cacctcaccc caaatttctc 201661 tattgattta atgtcacacc tgtcaaaatc ccagccagct ttttgtagaa attggccatc 201721 tgagctacaa ttatatttca tatattacat tatatgaaaa tgtaatgaac tggaattgcc 201781 agaacagttt tgaaaatgaa caaagtagga agacttacac tacttaattt cagaaacttt 201841 gtaaaaagct acagggatca agacagtatg ttatagttgt gaaaataaac atattgattc 201901 acagcataga atggaaagtt caaaaatgaa ccctgacatt tgtgggcagt tgatttttaa 201961 taagttgcaa ggcaattcaa tggagaaata actttttcaa taaatggtgc tatgacaatt 202021 ggatattcaa atgcaaaaag atatacaccc ttatataata atatacacaa atttcaactc 202081 aaaattgatc aaagacctca gtgtaggaga taaaagttaa aacttctgga aggaaatctg 202141 gtagaaaatt ttgtgccctt ggattacaca aatatttcat agatatgaca gcaaaaacgt 202201 aatatataaa tgaaaatcaa taaattggag ttgtcctctt aaaaagacac cattaaagaa 202261 atgaaaagac aagtcacaaa ttggtagaaa atatttccaa ataatatatt ggataaagga 202321 tttatattaa aaatatataa agaggtccaa aactcaatga tgaaaagacc cccacaattt 202381 ttttaaatgg ggaatttatt tgaatagaca tttcagcaaa gaaatatatg aatggcgaag 202441 atggccaaat aggaacagct ccagtctaca gctcccagcg tgagcgatgt agaagacagg 202501 tgatttctgc atttccaact gaggtaccag gttcatctca ctgggaagtg ttggaaagtg 202561 ggtgcaggac actgagtgca gtgcaccgag catgagccaa atcagggcga ggcatcgcct 202621 cacctgggaa gcacaagagg tcagggaatt ccctttccta gtcaaagaaa ggggtgacag 202681 acggcacctg gaaaatcagg tcactcccac cctaatactg tgcttttcca atggtcttag 202741 caaacggtac accaggagat tatatcccgt gcctggctct gagggtccta cacccgcgga 202801 gcctcactca ttgctagcac agcagtctga ggtcaaactg caaggtagca gcgaggctgg 202861 gggaggggca cccgccattg cccaggcttg agtaggtaaa caaagtggcc aggaagctca 202921 aactgggtgg agcccactgc agctcaagga ggcctgcctg cctctgtaga ctccacctct 202981 gggggcaggg catagccaaa caaaaggcag cagaaacctc tgcagactta aatgtccctg 203041 tctgacagct ttgaagagag tagtggttct cccagcacgc agctggagat ctgagaatgg 203101 acagactgcc tcctcaagtg ggtccctgac ccccgagtag cgtaagtggg aggcaccacc 203161 cagtaggggc agactgacac ctcacatggc cagttactcc tctgagacaa aacttgcaga 203221 ggaatgatca ggcagcaaca tttgctgttc accaatacct gctgttcttc agcctctgct 203281 gctgataccc aggcaaacag gtctggagtg gacctccagc aaactccaac agacctgcag 203341 ctgagggtac tgaatgttag aaggaaaact aacaaacaga aaggacatcc acaccaaaaa 203401 cccatctgta cgtcatcatc atcaaagacc aaaggtagat aaaaccacaa agatggggaa 203461 aaaacagagc agaaaaactg gaaactctaa aaatccgagt gcctctcctc ctccaaagga 203521 atgcagctcc tcaccagcaa cggaacaaag ctggacagag aatgactttg acaagttgag 203581 agaagcaggc ttcagacgat caaactactc cgaactaaag gaggaagtcc gaacccatgg 203641 caaagaagtt aaaaaccttg aaaaaacata gacaaatggc tcactagcat aaccagtgca 203701 gagaagtctt taaaggacct gatggagctg aaaaccaagg cacaagaact acatgacgaa 203761 tgtacaagcc tcagtagcca attcgatcaa ctggaagaaa gggtatcagt gatggaagat 203821 caaatgaatg aaattaagtg agaagagaag tttagagaaa aaagaataaa aagaaatgaa 203881 caaagcctcc aagaaatatg ggactatgtg aaaagaccaa atctacgtct gattggtgta 203941 cctgaaagtg acgaggagaa tggaaccaag ttggaaaaca ctcagcaaga tattacccag 204001 gagaagttcc ctaatctagc aaggcaggcc aacgttcaaa ttcaggaaat acagacaaca 204061 ccacaaagat actcctcgag aagagcaact ccaagacaca taattgtcag gttcaccaaa 204121 gttgaaatga aggaaaaaat gttaagggca gccagagaga aagattgggt tacccacaaa 204181 gggaagccca tcagactaac agtggatctc ttggcagaaa ccctacaagc cagaagagag 204241 tgggggccaa tattcaacat tcttaaagaa aagaattttc aacccagagt ttcatatcca 204301 gacaaactaa gcttcataag taaaggagaa ataaaatact ttacagaaag gcaaatgctg 204361 agagatttct gtcaccacca ggcctgccat acaagagacc ctgaaggaag cactaaacat 204421 agaaaggaac aactggtaac agccactgca aaaacatgcc aagttgtaaa gaccatcgag 204481 gctaggaaga aactgcatca actaacgagc aaaataacca gctaacatca taatgacagg 204541 atcaaattca cacataaaga tattaacctt aaatgtaaat gggctaaatg ctccaattaa 204601 aagacacaga ctggcaaatt ggataaagag tcaagaccca tcagtgtgct atattcagga 204661 aacccatctc atgtgcagag acacacatag gctcaaaata aagggatgga ggaagatcta 204721 ccaagcaaat gaaaaacaaa aaaaggcagg ggttgcaatc ctagtctgtg ataagacaga 204781 ctttaaacca acaaagatca aaagagacaa agaagaccat tacataatga atggtaaagg 204841 gatcaattca acaagaagag ctaattatcc taaatatata tgcacccaat acagaagcac 204901 ccagattcat aaagcaagtc cttagagacc tacgaagaga cttagactcc catacaataa 204961 taatgggaga ctttaacacc ccactgtcag cattagacag atcaatgaga cagaaagtta 205021 acgaggatat ccaggaactg aactcagctc tacaccaagt ggacctaata gacatctaca 205081 gaactctcca ccccaaatca acagaatata cattcttttc agcaccacac cacacctatt 205141 ccaaaattga ccacatagtt ggaagtaaag ctccccttag caactgtaga agaacagaag 205201 ttataacaaa ctgtctctca gaccacagtg caatcaaact agaactcagg attcagaaac 205261 tcactcaaaa ccgctcaact acatggaaac tgaacaacct gctcccgaat gactgctggg 205321 tacataacaa aatgaaggca gaaataaaga tgttctttga aaccaacgag aacaaagaca 205381 ctacatacca aaatctctgg gacacattca aagcagtgtg tagagggaaa tttatagcac 205441 taaatgccca caagagaaag caggaaagat ctaaaattga caccctaaca tcacaaatta 205501 aaagaactag agaagcaaga gcaaacacat tcaaaagcta gcagaaggca agaaataact 205561 aagatcagag cagaactcaa ggaaatagag acacaaaaaa cccttcaaag aaatgaatcc 205621 aggagctagt tttttgaaaa gatcaacaaa attgatagac cgctagtaag actaataaag 205681 aagaaaagag agaagaatca aatagaagca ataaaaaatg ataaagggga tatcaccacc 205741 aatcccacag aaatgcagac taccatcaga gaatactatg aacacctcta tgcaaataaa 205801 ctagaaaatc tagaggaaat ggataaattc ctggacacat acaccctccc aagactaaac 205861 caggaagaag ttgaatctct gaatagacca ataacaggct ctgaagttca gtcaataatt 205921 aatagcttac caaccaaaaa aagtccagga ccagatggat tcatagctga attctaccag 205981 aggtataagg aggagctggt accattcctt ctgaaactat tccaatcaat agaaaaagag 206041 gaaatcctcc ttaactcatt ttatgaggcc ggcatcatcc tgataccaaa gcctggcaga 206101 gacacaacaa aaaaagagaa ttttagacca atatccctca tgaacatcga tgcagaaatc 206161 ctcaataaaa tactgggaaa ccaagtccag caacacatca aaaagtttat ccaccatgat 206221 caagtgggca tcatcccagg gatgcaaggc tggttcaaca tatgcaaatc a^'aaaaaacgt 206281 aatccagcgt agaaacagaa ccaaagagaa aaaccacatg attatctgaa tagatgtgga 206341 aaagaccttt gacaaaattc aacaaccctt catgctaaaa actctcaata aattaggtat 206401 tgatgggagg tatctcaaaa taataagagc tatctatgac aaacccacag ccaataccat 206461 actgaatggg caaaaactgg aagcattccc tttgaaaact ggcacaagac agggatgccc 206521 tctctcacca ctcctattca acatagtgtt ggaagccagg gcaattaggc aggagaagga 206581 aataaagggt attcaattag gaaaagagga agtcaaattg tccctgtttg cagatgacat 206641 gattgtatat ctagaaaacc ccatcgtctc agcccaaaat gtccttaagc tgataagcaa 206701 cttcagcaaa gtctcaggat acaaaatcaa tgtacaaaaa tcacaagcat tcttatacat 206761 cagtaacaga caaacagaga gccaaatcat gagtgaactc ccattcacaa ttgcttcaaa 206821 gagaataaaa tatctaggaa tccaacttac aagggacgtg aaggacctct tcaaggagaa 206881 ctacaaacca ctgctcaatg aaataaaaga ggatacaaac aaatggaaga atattccctg 206941 ctcatggata ggaagaatca atatcgtgag aatggccata ctgcccaagg taatttatag 207001 attcagtgcc atccccatca agctaccaat gactttcttc acagaactgg aaaaaactac 207061 tttaaagttt atgtggaacc aaaaaagagc ccccattgcc aagtcaatcc taagacaaaa 207121 gaacaaagct ggaggcatca tgctacctga cttcaaacta tactacaagg ctacagtaac 207181 caaaacagca tggtactggt accaaaacag agatatagac caatggaaca gaacagagcc 207241 ctcagaaata acgccgcata tctacaacta tctgatcttt gacaaacctg agaaaaacaa 207301 gcaatgggga aaggattccc tatttaataa atggtgctgg gaaaactggc tagccatatg 207361 cagaaagctg aaactggatc ccttccttac accttataca aaaaataatt caagatggat 207421 taaagactta aacgttagac ctcaaaccat aaaaacccta gaagaaaacc taggcaatac 207481 cattcaggac ataggcatgg gcaaggactt catgtctaaa acaccaaaag caatggcaac 207541 aaaagccaaa attgacaaat gggatctaat taaactaaag agcttctgca cagcaaaaga 207601 aactatcatc agagtgaaca ggcaacctac agaatgggag aaaattttcg caatctactc 207661 atctgacaaa gggctaatat ccagaatcta caatgaactc aaacaaattt acaagaaaaa 207721 acaaacaacc ccatcaaaaa gtgggcgaag gatatgaaga gacacttctc aaaagaagac 207781 ttttgtacaa ccaaaagaca catgaaaaaa tgctcatcat cactggccat cagagaaatg 207841 caaatcaaag ccacaatgag ataccatctc acaccagtta gaattgcgat cattaaaaag 207901 tcaggaaaca acaggtgctg gagaggatgt ggagaaatag gaacactttt acactgttgg 207961 tgagactgta aactagttca accattgtgg aagtcagtgt ggcgattcct cagggatcta 208021 gaactagaaa taccatttga cccagccatc ccattactgg gtatataccc aaaggattat 208081 aaaacatgct gttataaaga cacatgccca tgtatgttta ttgtggcact attagcaata 208141 gcaaagactt ggaaccaacc caaatatcca acaatgataa actggattaa gaaaatgtgg 208201 cacatataca ccatggaata ctatgcagct ataaaaaatg atgagttcat gtcttttgta 208261 tggacatgga tgaagctgga aaccatcatt ctcagcaaac tatcgcaagg acaaaaaacc 208321 aaacacggca tgttctcact cataggtggt aattgaacaa tgagaacacg tggacacagg 208381 aaggggcata tcacacactg gggcctgttg tggggttggg gaagggggga cggattgcat 208441 taggagatat acctaatgtt aaatgacgag ttgctgggtg cagcacacca gcatggcaca 208501 tgtatacata tgttactaac ctgcacattg tgcacatgta ccccaaaact taaagtataa 208561 taataataaa aaaagaaata tatgaatggc taataagacc atgcaatggt tttcaaagtt 208621 gttaatcata aaggacatga aaattaaaaa ccacagtgag ctattactgc acacccagta 208681 taacggttat aattgagggg accaacaata ccaagtgttt catatggaat aatggaaccc 208741 ttaaacatag ctgttgggaa tatctgcttg tggtaccccc actttggaaa atagtttgac 208801 tgttttttaa aggttaaata ttaaattatc atatgaccca gtgacttcac tcctgggtat 208861 tgtctaccca agagagatga aaacatactt ccacatgaag acatttacct aagtgtttcc 208921 agtattatta tgcagaatag ccaaaatctg gaaacaagtt aaatgtccat caactgttga 208981 gttgataaat aaaatatggt atatttgtac agcagtaaaa aggagctaac tactgataac 209041 atgtttgaac ctcataaaca ctgtgctaag ttaaataaca cttggttgta tataccaagc 209101 gtattttgtt tgtttgtttc ttttgagatg gaatcttgct ctgtcgccca ggctggagtg 209161 cagtggcaca atctcagctc ccagaacttt ccagaaaaag ttgcctggga cgagctggga 209221 gcaaggattg acagtgaact gttacaactc tctggtgtag ggaaaatgtg tcagttctgg 209281 attgtgctta tagttgggca actgtataat aatttactga aaactattga attgtatgca 209341 tacaactggt gggttttacc atggataaat tatacttcag taaaattgtt taacaaaaat 209401 gactgatctg gctgggcgtg gtggctcatg cctgtaatcc cagcactttg ggaggctgaa 209461 gtgggtggat cacctgaggt cagacgtttg agaccagcct ggccaacatg gcaaaacccc 209521 gtctctacta aaaatattgt aaattagctg ggcacggtgg catgtgcctg taatcccagc 209581 tacttgggag gctgagacag aagaattgct tgaacccagg aggcagaggt tgcagtgagc 209641 tgagatcgcg ccactacact ccagcctggg caacaaagcg agactctgtc tcaaaaaaaa 209701 aaaatgatct taatgtaatg taatataaat aatagttagg gtccgaagaa tgtaaaacaa 209761 acaaatctga gttatggcat tggttgcaga actctgtgta gttactaaaa agcactgaat 209821 tttatactta cgggtggtat attttatggt ttgtaaatta tacctcacct acattttctc 209881 ctaattttat taaaataccg atttataggt ttagccaaaa aagaagaaaa ttcaagtgtc 209941 aacattagtg atttaatatc tttatctatt tctctttctt ccaaattctc taaatatgtg 210001 ttacttttat tatcagaaat aaaacttttg ttgactctaa acttctgtaa ctgatacctc 210061 ctagtctcaa agatcttaaa atttattagt aaagaaagat gtataattgg ttgaattata 210121 ggactgtaat tgccaaagtc tgttgaaggg aaagagtgag atagaaatcg tgggtaaatt 210181 aaaagagctt tgaaactgat agaagaggtg gcccttgagt aagtactctt acagtcggaa 210241 ggaaagtttc aggggtctct tgttgatgct atccagctgt cctgtcatta caaaaaacat 210301 gagccacatt ttacatcaga gctttttttt aaaaaaatta tcattcctgt caatttttga 210361 caaataattt taatcacaaa atacttgttt agcgagagaa aataacccaa tatgagcaaa 210421 aaacaaaaat aaaaactaca ttgtggccgg gcgtggtggc tcaatcctgt aatcccagca 210481 ctttgggagc ctgaggcagg cagatcgctg aggtcaggag ttcgagacca gcctggccaa 210541 catggtgaaa ccccatcttt actaaaaata caaaaattag ccaggcgtgg tggctcacac 210601 ctgtaatcgc agctactagg gaggcaggag aattgcttga accgaggagg tggaggttgc 210661 agtgagccga gattgtgcca ctgcactcca gcctgggcga cagagcaaga ttccatctca 210721 aaagaaacaa acaaaactta ttgagtaact tatgcagcca ggaagctgat tgtaaatggc 210781 aactgacaag ctgaactttt atgattccat agtggagaag cagccagaga agctacatct 210841 cagaagaagg actctcttgc ctttttaaaa tttgagtctt cctcagctct gctttgagca 210901 tccttcaagg tcatgttagt gctgcctctt ccctgaaatc tttctggctt tcatagaaac 210961 aatctttttc cttcttttta ctttttgttc atttttgttg ttgttgtttt atttgtgtac 211021 acttaccttt tagcacttac tacattgtac tttatgatac agtcaattgt gttcaattat 211081 aaactattgc caacttaggg ctttatgttc taagggttgt ggtgtgaacc aagcactgac 211141 tagtaatatc caaactcttt tcctattgcc atcaaaatgg aactaaacca gagtgcagtt 211201 tgtgtttcaa tataatttaa gcagtaatga aaatggccat atcaacaaac atatgaaaaa 211261 aagctcatca tcactggtca ttatataaat gtaaatcaaa accactatga gatatcatct 211321 catgccagtt agaatggcaa tcattaaaaa gtcagggaac aacagatgct ggtgaggctg 211381 tggagaaata ggaacacttt tacactattg gtggagtgta aattagttca accattgtgg 211441 aatgcagtat ggcaattcct caaggaccta gaaccggaaa taacatttga cccagcagtc 211501 ccattactgg gtatataccc aaaggattat aaatcatttt actataaaga cacatacaca 211561 catatgttta ttgtggcatt attcacaata gcaaagactt ggaaccaatc caaatgccca 211621 tcaacgatag actggataaa gaaaatgtgg cacatgtata ccatggaata ctatgcagcc 211681 ataaaaaaga atgagttcat gtcttttgca gggacatgga tgaagctgga agccatcatt 211741 ctcagcaaac taacacagaa acagaaaacc aaacactgca tgttctcact cataagtggg 211801 agttgaacaa tgagaacaca tggacacagg gagggtaact tcacacactg gggcctttcc 211861 ggggatgggg ggtaagggga gggggagaat caggacaaac acctaatgca tgcggggctt 211921 aagacctaga agatgggttg ataggtgcag caaaccacca tggcacgtgt atgcctatgt 211981 aacaaacctg catgttctat acatgtatcc cagaacttaa aattttttta aaaaaagggc 212041 catagtggtt tctgaatgaa aagagttaga gatcactgat gtggtcatgg cagacatggg 212101 atttgggctg agccttcaaa cgtagataaa attcctataa acataaatga acagagaaag 212161 acataactgc cagggcagct ggctggagta ggactagtac ttccactcca catcaaccaa 212221 caccaccacc agtttggctg gcatagagag aattaaatat cttgctagta gggtgtgtgg 212281 gttgctcctg aaagttttct aatgaaaact cgagctgctc agatgttcac tgttattcta 212341 ctaaaaagat aatctgggta ttgttctgtg cggtgtcagt ttctaggact tattttcttt 212401 atacttgttg tttgttacta ttccttttgt tactttggca tgaatttaat tattgacact 212461 ggatcattaa tgtggccagg gcatttggga tgattggtca ggagacccag ggatctgtaa 212521 gaaaatgtca tcctgggaaa gaggagatat aacaagatat tgaagattgt gtccagttca 212581 gggatattag taaattctga gaaagatttg agtatcttca gcgagggtga gtttgaggtt 212641 gataggacta cgtacagaaa cagggaagtc agacgtggca acagttttag ggccaaagtg 212701 actgaattca tgtggtatgt actgaaactg aggtgataac catttatccc agtaaatcac 212761 tgaatctgag gatataaaag ctgaaaagag cattagtggt gatgtaatct gttcccacca 212821 ttttacaaga gaacaagtga gtcctagagc gagtaggtag tttgaactac caagatcagg 212881 agtgaaagtc gtatgagtca tcactgcaga gaagatggtc agagatctgg cagtgaatca 212941 cttagttaaa atacagctct caccacagat tatatctgat cttggtgtga agtgccaaaa 213001 aacacgtcat tcagatctct ctgtatttta tattttctcc tgacattttg gaatgtggtg 213061 gaactcttca aaagactatc aaataattcc tattttaatt ttataaaagg aaaattaata 213121 gcatatgtgg ggaaaatgta ccatatagta cattgtggga aaagtgtaga agtagagaat 213181 taagggaaat tttagtatgg gtcatttata tattttggac acatgccatt tcagtcaagt 213241 ccttgagtat acccgtaaga atcgaattga taatcgtact tttaaaaacc ctagcaacct 213301 gaacaggacc caagaaatag aattaaagaa aataataagc cagaacttgg cggtggttct 213361 gttatctgtg agcttgacac tctttccttt ttgtcctaaa gtttcagact ggaatgggca 213421 ggaatcaaca gcaggggtca gttttaatga tgctaacttg gtgtaacaaa attatttagg 213481 attataaaat tttcttgata gagactgaga ttagtttttc tgtaggaatt tttgtttgtt 213541 tgtttgtttt aagaattgat ccagtttctg tgatgaacag cagattggtg gagctggctt 213601 atttagaatg acctgtgtaa tattttttaa aagttctaaa tgcatagtag tctcttagta 213661 agtggttgtc tctgttgtta ctttctaaat gcctttgatt aaattgtaag attgtaagcc 213721 gttaggaagc agttcaacat ttctactctc agggacttcc aaggttgatt tggatctgga 213781 gtagctcttc tcctctgcct gttttatgtt aatacatttg gattattccg gatggttcat 213841 ggtgggtaag ggaaccaatc tcccaccatc taccctttct aaccagcaga ctgtaagccc 213901 acagaattga ttaccagaca gattcacacc taagcccatc tgactcttaa agcacagctc 213961 ttaacactag gaagtgctgc ttcccggagg caggattata gaagttaaga cttaaccctg 214021 aagtgatttg ctagttgatt ggccaggagc tgcagactgt taccccaact cctgctccag 214081 atttcctttc ttagtcaaat gcacacagtc ctctctagca taactgtgaa tgtgttagaa 214141 aacaatcaaa acttgtctgg caatgattca cacataacca attaagtσct ggaaaaatgg 214201 attaaccaga tattaaacat tttgctgttt catgggcagt taatatagtg gaacttattt 214261 acatcacacg atggaaaaat tagtgcaaaa aatattttta agttgttgcc ttatcaggag 214321 agctaaatca aactgaaaat gggaaaacat gaaagttcaa ctgccaacca cacaaatttg 214381 ttttcaaatg catgcttaaa tgttttcaga actgaggaat cactggcagt ttagttacaa 214441 cttgaataac tatacttctg gatacttctt atattcccag aagatttctg cctcactaat 214501 agcttatgga aaatacttgg ccaataagct catgctatta taatttcaga tttactgaaa 214561 ctattaaaaa tgaagtaaaa aatattctga ataagcaacg agtaatagta aatttggttt 214621 attaggaata atttcctctc aactttgaaa tttatgtatg ttatggaaaa attactggca 214681 ttgaatttgc agtgtgttta ataggaagtc ctgccttctt taagtaacac attcattaat 214741 ctgatatgtt ttcagtaaaa caaaatctta aaacccacaa agagcaaatg accaatattt 214801 tctctctctc tatgtgtgtg tgtatatata tgtgtgtgtg tgtgtgtgtg tgtatatata 214861 tataatttgt tactgaaact ttttatttgc tgccataata ttatacatat tgctgtattt 214921 ggagtaaaaa tatgactaga gaaatatatg ggcatttttt tagtgatttg ataaacccgt 214981 gtgttgcttt tgggcttcat gaagcatcta ggcaaattct ttaagtacag tgatatattg 215041 ttttggtctg tgcatggagt tgttactgga aacttcatgt gtcattggag agcaatatat 215101 ggccttttct atttcagaga tgaagtataa tgcaaaagca gatttgagat gacagtcaag 215161 aactgagatt ttcaaacctc tagacttttt aaatgaagaa tatttatttt tctttgttta 215221 caaggaagta actgaaatga tttgttatgc atatgtgatc cagaaggtat ctagcaagtg 215281 ttctttaatg _rctagtatttc caggttacag ttcctttctg tttacatgca cataaatata 215341 cacattgaca catttctgca aatgaaatgc ctattttaga taactcatgt ttactaactg 215401 caatttgtgt tttacatttc cctttggagt tttttttttt ttaaatttca tggaaagaaa 215461 catgtagaaa attgtgttct ttttaattac tgtaggcctg gttgagttca tggaatgacc 215521 ctaagcaatt tgtagtcttt aaagaaaaga gagaagacat tacttgaaga ttttaaatca 215581 tgtaaaatgc atatattaat gtagaaaacc agttttttga tagctttcag ttttgtgaga 215641 aatgttagcc ttcctccagt aggaagaaga ggatttgcaa tacttaacat ttccttttct 215701 ctggatgggc aacagaatta tcatctttta gacaattttg gtaaaataat aattcaatca 215761 ggactcaata agttaagaaa gtacacagta attcaagcat aggaattaat cttctgtaga 215821 atttttcaaa taaatactag aatgttttaa aggttatcag ttacctttcc aaatttttgg 215881 tcatccttaa catcattttg tcatttgaca ccatttgcta ctaccactga acaactgtct 215941 ctttctgtag tttcattatg ccacacattc ctgaggtttt tgcgccccca accccacttt 216001 tttgtatttg aagttccaag ggttgccaga ttagattttg tatgcccagt taaatttgaa 216061 tttcatataa gaagttaata tattttttag tatgagtatg acccttgcag cacttaactg 216121 ggcatcctgt atttttattt gctaaatatg gcatcttgaa gtcctctgtc ttctctaaga 216181 aggttttcct ctctttctgc ttccttgggc atcccaccaa tccaagacct tgattctctt 216241 tacctcctga tgagagtgca ttgatgtggt ttggctctgt gtccctaccc aaatctcatc 216301 tcaaattgta atccccacat gtcagaggag gggcctggtg ggagatgatt ggatcatggg 216361 gtggatttct cccttgctgt tcttgtaata atgagtgact tcttatgaga gcttttggtt 216421 taaaagtgac atttccctgc ctcgctctgt ctctcctgcc accatgtaag atatgccttt 216481 cttctccttc accttccgcc atgactgtaa gtttcctgag gcctccccag ccatgtggaa 216541 ctgtgagtca attaaacctc ttctctttat aaattaccca gtctcaggta gttctttata 216601 gcagtgtgaa aacagactaa tacatgcgtc taaccttatg gaacaagttg tcacctcttt 216661 gtgctgattt ccagtccaca tctctaacct tgcctgattt agccccaaat ttcagaaaac 216721 ctactataac tctagttgca tctggtgcta gtatctccaa ctaaacatga ccaagctgaa 216781 ctctattttg aatgctccag accacgtatc ccaattgcct tcagggttta cattgttttc 216841 attaactgaa agatatcagt ttctcaggtt gtctatgcca gggtcatgtt agaccctcct 216901 cacaagacat ctctcaacat gtttgtagag ttttcatcaa aatggctacc acttcatcat 216961 ctgcttttga gtttcattgc tattatccta ttcagttata aagtattgat ggttcttgga 217021 gtaagtttct tttctgggcc cttctgatta tatgtccctt ctttcacatt cctctacatt 217081 ctgctgctag attagtcttc tttcatcaca gtctcttaga tcatgttccc tggaaaccta 217141 tgttgcatgc aggtttattg gagaatgatt caggagacac agctataagg aagtgagaaa 217201 ggcagggttg ggcagagaga gttgacccac atgaagttgt acctaaaacc tcaggtgatc 217261 ctacagagtg ttccaagctg ggttgagttt ttagatttgt caaaaattaa ggccgagggc 217321 caggccatta tgcccgacca tgctctcctg agtgaccttt gaggtccatt tcagagtccc 217381 tctaatttct ttgttcgtgt ggctgtcctt tgctctgtaa ctgccctctg agtctcctcc 217441 tctctgcctc ctcaagggcc tggctatgag caactcaccc catgagagga ggcagaaact 217501 ggaggaggct tccacagcta agatctcttt ccaccaaatg atacagctgt ggagtagctg 217561 aaggatgggt ctgttggcac caaagagggc tgtgagatga gctccacaat gttcaccaca 217621 atcactgtca acatttcact ttcctgctta gggacctttg gtgtattccc tatactgctt 217681 tatcaaggta aatgttacta ttagacttcc ggggtcccat cattatctga ccccaccttg 217741 cctgtcactg aacccaattt ctccctatct tcagtgtctc cctccagtcc attaagggtt 217801 actcctacct ggaaagtctg ctctttagct tccttgagac ccctgcccac tqattgtcca 217861 tgctgtacct tcgttcaggc cttaggcctt tgcttctgct atccttcctt ctggaatgtc 217921 ccctcttctc taagtcttct gttcatcttt aatcccctgc gggtgaatca atcctgctta 217981 ttattaatac tgtgtaattc tattattcat tgtatactag ctcttatttt ttcattagct 218041 ccatgtatgc tgttcttgtc ttcagtattt attttggacg atgagactgt ttttggtatt 218101 tttggcagta tctagcagaa tgctaggctc atagtagtga atcaatgact gctttactcc 218161 ttgattatat ttgtatatgg cacgtccaaa atattaatac tgaaagtggt gagataagat 218221 ggagagagtt ttctagtaag attgtatttg agctccactg gtgaacttcc ctgaaagaat 218281 ttcagagtta catgtgtgta cgggtttggg tggctcctac atggatgatc tgaagtaaga 218341 gcatgaatta acagctgctg tttccctctc ctcttatctc actttagtct cccacactgt 218401 gctgggacca ttgcagactt ggagtctctt ctctgtgatt ccagcccacc ttttggagtt 218461 cacttcttgt cctgatgccc agtgctgtgc tcccctccac tccttttgct gcccagtaac 218521 tctcttccct tacctgcaga gcagcctttg ccctggacat tagcaccatg ctctgactct 218581 tcctggccaa ctctcccctt caaaacttag gtgcataaat gaatgaacta catttacata 218641 caataaaaca taatgttgcc tgaaaaaagg cagacacaaa agagcacata atgattgttg 218701 caaagatgga caaaactaat atctggtgtt gtaatcagta ttgtagtaac tcgtggaagg 218761 ggcagtcttt agaagggatt atgaaaaggc ttctagaatg ctaggaatct ttaatttctt 218821 gaccaggtgc agatttcatg gatgtataat gcttgcactg tgtacttatg atttgtgctt 218881 ccttgtatgt atgttatact ctgacaaaaa gttttaaaat catttatctg cttggtaagc 218941 tgatcacttt ataaactctt cagtgaacag gggctagtgt gttgctcttc ccagtagtac 219001 taattaggag ataatagaaa tagaggaatc ataaagttgg ccctctgtgt ccaccctctt 219061 tatggtggtt ctagggagga cttggaggct gtcaagctca tccagatgct tctggatatt 219121 agcatacatt aatcaaaatt catgttcaaa gtcttaaatt tttcttctaa cagagccaag 219181 ctaccagatt atttttcttt atgtcttatt aattcccaaa ggagatatct actctatctt 219241 cagaaataaa gaatagttga ttttgagttt cgttaagtat tctaaataga atgacaattt 219301 ctgttttgaa aaataatttc ccattgaatc ttcaaaataa ctgggaaaga aagattgagg 219361 tagagttaac aattctgatt gttatttctc actacatcct tcaatttgga tgtactttct 219421 cgtggcacaa aggcttccgg cacagagaga agaagccctg ttgggttttt ccactttgac 219481 ttgggtggtg taaattaatg tgatcagatc ggaaaggtgc aggaacagaa agtgcatgca 219541 gcaagttgta gtaggaggga gtaggtattt cgaatcaacc aaacctagtc ttcaggctgg 219601 gcatcggcac ttagtcagtg tgtgaactta ggcagactgt ttaacctttc ctctaacaga 219661 gtggtaacat gccctctccc tgtgccaagt tcttgtgaag actagacacc ctgagtatga 219721 agctgcagat tcaggctgtg atggttactg ccattgtgac atgggactag aacagagagg 219781 acacacattt tcacattgtt attttgaatg cactgtattt ctatattcta taaagatggc 219841 acatagtagg cacttttcat atttcttgga aataaaaatg aatacaagga aacaattctt 219901 gctctccaaa caataactca aaattttggg aaagaaaaca attttatggc catatgttgg 219961 taagtagtac agaatctttc ataaatacaa aggaactcta aagtgaatga agatgcttgt 220021 gatgtgagct ttgtcaggaa cggttatatt aacagatgta ggtgtgactg aagcttaatt 220081 ttggaaaatc agtcataatg acaatagaca atgttgattc tacatggtct tcgagctggg 220141 cacttgactt cctgctttac atgtgttata tcctctaatc cacacaacta ctctgggaag 220201 agttagctgc cagcatgatc tccattatag gtgagaaaat caaagcttca ggagaagaat 220261 gtcacttacc cagaatcaca cagttagtgg aatggggcag gtgtctgtgt ccaaaagccc 220321 ttgtagccat ctgcatcaac ctaagagtga acatggtgtt tgtagggcat agtaccgaag 220381 aggttttgga aacagttgct ctcaggaagc tgtgagtcag ttggagaatt aataattcta 220441 cctctgtgtt cttaaatctc agcagaagag tagctcataa acagttatat caaggagggg 220501 aaatcatgtg gatgtagagt gagaactgat tttaagttgc tgctactcat tatgtgctgt 220561 gcagccttgg acaagttact taacaaaatt gagcatctgt ttccttaaaa tatccttaaa 220621 cagggtagag agataatata ctttgccatt tttgatctat ggggctattg taatgatctg 220681 gtggatttat gaaattgtca agtgcaacaa agtaagttat ttttgttaat agttcaagta 220741 atagatgtgg tgatggtaat aataatatga tgatatagca attattgtaa taacttaaaa 220801 tagtaataaa aatagacaat ataacttgga gtcagatggc cacaaggatt gaattgcctt 220861 ttgctggcaa tatttcaaat attttctgat taagttgttt tgctagattc gtagtttgtg 220921 gctttggctc agacaagcaa ttaaattctc ctcaggaaat catgaaaggt tacctttggt 220981 tgtacagcct acactgttga aattttggct tcaattcagg attcatggac aaattaacat 221041 ctgaatcact tgagacctat tcataaagaa taggatgatg tatataacta aagcttatgt 221101 gcatagctaa agtgacttga gtttcacaat gaagctggga gatggagact atactcccgt 221161 actctgagtc acctactgca gggcagccat ctatggggct gtgatggtgt ttatatgtaa 221221 gtgagcatcg gacttggttg gagctcgctg atttaatgga ggatgcctcc agtctagcaa 221281 gtgaggtttg taaagggccc tgtaggaccc tccaagaaaa gttatgtata aaggagagtt 221341 atactcattt gcaaatcatt tcttaaagta aaatgcccat gaaagtcagt aacaccatag 221401 tttgtttcta aaaagtaaac ttaaatactt ttagaggact tcagagctag aaaacattta 221461 tatcttactt agagtggtca ttacccttgc ctgccttgct gtggtataag taatgaaatt 221521 gtgtatacaa actgttatcg tggcagggat tattattaga taatttcttt gtataacctt 221581 aaaaaatatg gcatgttatg caaattatac gaaatgtatt tcttactaac ataatttcag 221641 ggtagtgtga agctcaattt tagggatttg ggaaataaat gtgaattatt tttattaagc 221701 tgttttgcta agatgactaa ttctgaccaa caatttctgt atcgtagatc tacttattat 221761 ttaaaacttt tattactcat gttttcaaaa agattctttg aggatagatt aagtaaaaat 221821 gaccacacag tgtagtgtgg tagttatgtc tctgttagtc aaaatttcta gcagttttag 221881 ttttaaagat atgattagtc atctgtatag aaatttcaat aaattgcttt tgcaattata 221941 gctatcttag aagaatttct tccagagaag ttgagtaaga atgccaatta attccagctg 222001 ttggagtgaa ttgtatgta^'g aatgtctatg agttcaaccg tcagtaaact aggacaaagc 222061 tcttaaatgt tataatttca caatcaaaaa actttgcaac cagttgtcca cttattagac 222121 tgaattattg aatgaagcat tagtttcttc agtatttatt tatatttatt tatttttttg 222181 agatggagtc tcactcctgt tacccaggct agagtgcagt ggcgtgatct cggctcactg 222241 cagcctctgc ctcccaggtt caagcaattc tcctgcctca gccttgtgag tagctgggac 222301 tactggcgcc cacccccact cccagctaat ttttgtattt ttagtagaga cagggtttca 222361 ccacgttgtc caggctggtc ttgatcacct gacctcatga tctgcccacc ttgggctccc 222421 aaagtgctgg gattacaggc atgagccacc gcattcagcc tcttcagttt atttttaaag 222481 aactcagtat ccctggcact gttggccatc tctgtggaga tactagttct agcaggaagg 222541 caaggttggg ggagtttttt gttttttaaa aaggcttaat ttttaattaa aaaatttttt 222601 aaattatgtt ttttcattac acttgcatag tcagttatgt gtgtgtgttt taattgactt 222661 tattttttag aactgtttta ggtttatgga gaaattgagt gtaaagtcca gagatcccat 222721 atacttcttt tccctggcac acagttccct ttattattaa catcttgtat tattgtggta 222781 cattcattac aattcaattg atacaattga tgaaccaaat ttatacatta atattatcta 222841 aagtgcagag cttacatcag ggttcactct gttgtatagt tctttgggtt ttgacaagtg 222901 catgatgtat ttacatatct acatgtagat attacataca tgcagatata taatatctgc 222961 atgatattac agtatcatgc agaatacttt cattgctgcc caacccccca ccccacccct 223021 gctgcctgtc cctgtcttcc atctacttac accctgctta tacccatccc aatcccgtca 223081 accactcatg tttctgtctt aatggttttg tcttttctag aatgtcatac agtagaacga 223141 tagattgtat agccttttcc tattggcttc tttcattcag caatttgcat ttaaagttcc 223201 tgtatatctt tttgtgaatt gatatctcat ttctttttgt catggaataa tattctattg 223261 tatggatgta ccacagttta tttatttatt tacctgtgga aggacatctt ggttgcttcc 223321 aagttttgcc aattatgaat aaagcagcta tacacattca tgtgcaggtt tttgcatgga 223381 catacatttt caactcattt gaatacttaa tttccattta cctagcattg agatcaaata 223441 gacactgagt atatagatga aggtcaagaa aaacacacca ttcctatgag aataagaggt 223501 agtggaagat agaacacgga gggtttaaaa gtatgggtcc tgcagaaacg ccaacctgtc 223561 ttctgccagt gggtaaatgg accatgggga gaaactggaa ggacgttttc ttcttggtta 223621 catttcagaa taatctagag gagtaccaat taagcatcct taatccattc caatttttga 223681 cctagttaat tcaattccca gaaacacttt taaaatgcat ttataaattt aatatatttg 223741 gttcttttaa agcctccaaa tgccttgatc taacaaccag aacttctcca tgtgatagct 223801 taaaagcttt tcttgtaaac ccaataaaac aaaatttgta tatgtagttt ctcttaagca 223861 ttctagtatt ggtgggaacc tagtaaaatt gttttatacc tttcaattta aaaatcacat 223921 tttaaaataa aagaaattga tattacatgc atagtctatt actatatcaa actgtcttaa 223981 acgtaatact ttatgaacta aatattgaaa cctgtccaaa tgattacata ttgattccta 224041 aacttaacct ccaaggttta aatactgtgg gtttgcttta aaataattat gtctgtattt 224101 aaaactaaat atttccagag tccttgtcac ccagagtgat ttatagttct catctctgga 224161 agtggtgttg ttatataacg tggtttaggt aacttaccag ccagtgatct gagacctgtt 224221 ggaggtctgc catgtggacc cagcagtatt cttctctccc acccattgac agatgcttga 224281 caccattttg tatagtcagt atcacaatcg gaggattcta agtctctacc ttgaagtaat 224341 tatttttcta ccttgaagta attattttat ttcatttgaa tctgcattct tctgaatcgg 224401 gagacaccta acttccttca gctaatctct taaacttctc attgaattct ctatttgttt 224461 aatatttttt ttccctattg gttaggtcac aactcttaaa acttttgaaa tctaatatta 224521 ccgaattctc cagatctctc acacctctgt ctctgtagct atactgctaa gatcttgcta 224581 atgacagcta tgtctgactg agtttcctgt ggagatactc atctgcttgt tgaattaccc 224641 actgacagaa ctgtaaccat gaatcatatg tattaaggaa aagtaaagaa attatactct 224701 tttacaattc agatgtttga ggtctctgtt gacacgttat atatgaatgt atcctgtatg 224761 tggcagagcg agtttcaaat acaactaaag gtttttcaca aaagtttcat tatgaagtac 224821 tatattagtc cagttgcata ctgctgtgaa gaactactgg agattgggca atttataaac 224881 aaaggaagtt tgatcgactc acagatctgc atgtctgggg gaggcctcag gaaacttaca 224941 attatggcag aaggggaagc aaggcacatc ttacatggca gcaggagaga gaaacagaga 225001 gtgaagcggg aagtgccaca cttttaaacc atcagctctt gtgagaattc attcactatc 225061 atgagcacag catgagggaa actaccccca tgtaatacct actccagtga caatgtaggt 225121 attacaattt gagatgggat ttgggtgggg acacagccaa accatatcat tctccccctg 225181 gcctctccca aatctcatgt ctttctcaca tttcagaacc catcatgcct tcccagcagt 225241 ctcccaaagt cttaactcat tctagtacta actcaaaagt ccaagtccaa agtcccatct 225301 gacacaagca agtcccttct gaatatgagc ctgtaaaatc gaaaacaact tagttacttc 225361 caagatacag tgggggtaca ggcattgggt aaatgttccc attctaacag ggagaaattg 225421 gccaaaacct aggggcttca ggccccatga aagtctgaaa tccagcaggg cagtcattaa 225481 atcctttttt tttgagatgg agcctcactc tgttgcctaa actggagtgc agtggcatga 225541 ttttggctca cggcaacctc cgccccccca ggttcaagca gttctcctga ctcagcctcc 225601 caagtagctg ggactacaga tgcatgccac cacaaccggc taatttttgt atttttagta 225661 gagacagggt ttcaccatgt tggtcaggct ggtctcaaac tcctgacctc agatgataca 225721 cccgcctcgg cctcccaaag tgctgggatt acaggcatga gacactgccc ggctagtcat 225781 taaatcttaa agctccaaaa cagttacctt tgactccata tctcacatcc agggcactct 225841 catgcaaagt gtgggctcct aaggccttgg gcagctctgc ctctgtggct ttgccaggta 225901 gagcccccat tgctgccttc acgggctggt gttgaatgtc tgtggctttt ccaggccttt 225961 ggtgcaagct gttggtggat ctaccattct ggggtctgga gaacagcggc cttcttctca 226021 cagctccact aggcagtgcc ctagtggtga ttctgtgtgg gggctccaac cccacatttt 226081 gcctctgcat cgccctagta gaggttctct ataaggactc ctcccctgca gcagacttct 226141 gcctggacat tcaggcattt ccatacatcc tctgaaatct aggtggaggt ttccaatcct 226201 caactcttgt cttctgcaca cccacaagcc caacaccaca tggaagcctc caaggctcca 226261 aggcttgcaa cctctgaagc aaaggcccaa gttgtaactt ggtgcctttt agccatggct 226321 ggagctggaa tggccaggat gcaaggcacc atgtcccaag gctgcacaga acagcagggc 226381 cctgggcctg gcccatgaag tcatttttcc ctcctaggct tctgggcttg tggtgggagg 226441 ggctgctgca aagatctctg aaatgccctg gatacgtttt ccccattgtc gtggctatta 226501 ccattcggct tcttttttct tatgctaatc tctgcagctg gcttgaatat ctccccagaa 226561 aatgggtttt tcttttctac cacatggtca ggctggaaat tttccaaact tttatgctct 226621 gcctcccttt taaacataag ttccaatgtc agaccatctc tttgtgaaca catatgactc 226681 tacactgtta agagcactca ggctctgctg ctttgctgct tggaaattta ttttgccaga 226741 tatcctaatt catctttctc aagtttaaat ttccacagat ctctagggca ggagcaaaat 226801 gacactaatc tccttgctaa agcatagcaa gagtgacctt tactccagtt cccaataagt 226861 tcctcatctc catctgagac cacttgaacc tggacttcat tgtccatatc actatcagca 226921 ttttggtcaa aaccattcaa caagtcttta ggaaattcct agctttcacg caactttctg 226981 tcttctgagc cttccaaact gtttcagcct ctgtccatta cccagttcca aagtcacttc 227041 cacattttca ggtatcttta tagcagtacc ccactctcag tgccactttt ctgtattagt 227101 tcattttcac actgctataa ataactacct gagacttggt aatttataaa caaaagaggt 227161 ttaattgact cacagttcag caagggtggg gaggcctcag gaaacatata atcattgcag 227221 aaggtgaagg ggaagcacga cacatcttac gtggtgggag gagagagaga gaacgatggg 227281 tgaggtgcca cagttttaac ctatcagatc ttgtgagaac tcaccattat gagagcagga 227341 tgggggaacc tccccgatga tccaatcacc tcccaccagg accctcccct tgacacatgg 227401 agattacagt ttgaggtgag atttgggtgg agacacagag ccaaactgta ttaagtacaa 227461 tttttagatt agatttttgg gactgacttg gctctttcag cccctgtatc tagtccatca 227521 gtacatttag tggctccacc tgcagaatag atctggaatc tgacagctta tcaccacttc 227581 cttggctgcc attctctctt gcttgggctc tattgttata ttgacacttg actgtttttt 227641 ttttccccca cccttttccc cattatctgt cttccacata gcagttagca gattgtcatt 227701 ctaccactat caatcctcca gtagcattag tcataataga ctaatagcca aattctttac 227761 ctgtatgttg tagatcctgg cttgtcctca acctcatgtc ccatcaatat tcttagccac 227821 actggtctcc ttgtttttct ttaatctcac agcacatgag gttccccctc agaacctttg 227881 gacttactgt gcctcatcta gtaactctct gccctctaat attattagca tgtccctctc 227941 ccttatccaa tcaggtctct gctcaagaga ttacctcctc aaagatgtct tcagagaata 228001 catctgatca tttttttctg atttaaactc cctctctgcc cctccataca tcctacccta 228061 gttccagtca ctctatggcc tcttcactgg ctatttttat ttataatact taaaaaaggc 228121 tggcattgtt atgtatgtgt atttgtttat tgttacaaat ttactggtat aactccagca 228181 cctagaataa ttcttggcac cagtaagtgt tcagaaacac ttgtaggagt aatcttctgt 228241 agaagtaatc ttctgtagga gtagaaggac taatctcccc accttccctg atgcttgtag 228301 tgatggagag gcccaaggga aagttacaca taagagaccc caatgagaac actgttattg 228361 gacccatagc tgattgactt aggcttccta aagtagcttg tcattttcag catggaattt 228421 acattagaca atttagtttt tttttaagcc actttactta acaatttata gtaaaatacc 228481 tacttgttaa aagaagatag gtatgtttaa aaggaaaata cctgaaaata ccttacataa 228541 gtttgaattt ttaaaagagt caatcagcat ggaaaaaatg aacatattgt taaatattga 228601 agtatcattg ataagtcttg tggttgaaag tgctatacaa tgcaggaaac acttttcctc 228661 tacattatct taagcatgtg tgtgggccgg aggtcaggtt taataaaaat actttagctt 228721 aagaacatag gtcatgaaaa ggagcttatg taaaaggctt tgaagaagtt cttatagagg 228781 aagtcactca gtgtagtggg ttacaatgcc ttgagtaggt cagaggcgat gagaaagtca 228841 catggctagg gccttggtga atgtttctgg gactgtcagt ggtgtctgca tgatctcttc 228901 tcatgctagt agccatttcc cacatccagc catcaccttg tcacccatca tgtcagcact 228961 tagctgtcga ctctgtttgc cattgtcttt tctttaaaga agtagcagag gagtgatatt 229021 gggttattca gaataaccag gtctgggcat agcttcagca tttccacttc ctgtctcatg

229081 agctcatttt gttttaaatc tcattcatgt tctataaaga tggggatgct tccaactatt

229141 agttgattga taattgaaaa caacttcatt tctaaaattt gtgaaaccat tagtcacaca

229201 atggctataa tatgaacacc atgtaaaggc tctatgatgg taattgtaca atgtatctgc

229261 atgtcagaat cccttgggaa gcatttataa atgcataccc cagatatact gaatcagaat

229321 ctttgaggct gaggtacaac aatcccattt ttaaagtttc ctagggactt tgatatgttt

229381 tcctgtttgc aaccactcat ctgggggcac aagaaaagtt ataaggcata ttttctgtct

229441 tcaagtctct tgtgtctagt tcaaaaatga aaatgagaac aaatggccca gttagacaat

229501 gcattggagt tggttttctg tttgtgtgtt tgattggtgt gaatgaagag tagtctagat

229561 aaggcagcat gtggttggta tccttgattt attgttggat aaagcaccag atagtctgac

229621 tagtattgca aggtttattt tagtgtatga atcattagta tggcttcaaa aatgtataat

229681 gttaaatagc cttttatgta gcttgtatct ccccttctac tttcgaagct ggcaagattt

229741 ttaagaaagg acttaaaaat agacccaatc attttggtca aatttgtttt tagggtgaaa

229801 atgaacaaac ccctcatacc ttttataaat tggcttgcat ttcctttcaa attcctgtaa

229861 gaatgtaaac tttggatatt tcatagtagc tctaataatt ctaacaacaa tttaaaacca

229921 tttagaccaa tttacccaat tgccttaata aaaggctgtt ctggcagtga ctaaaagacc

229981 ccttggtggt gcttaaataa attattagct cttgatgttt gtcatcatat ggtcttaggc

230041 tcaaaatatc agtggccttc tgaaacttta ttgtaaggac atttattaag taaatgatct

230101 gaaaataaga tggaagcaat tcgaggaaat tatgtctcta ctttgtatct ctcatttagc

230161 atatgtacaa ttactacatt ttcctacaaa ttactttgaa agatatatta atcaacagtg

230221 gtagtaggta ttattagaga acaaagccat gattatcaaa tacatttgtt ttgttaaaac

230281 aatgggagta tgtcagacat atagattgac ttccttgaag acaagtgaaa agcaagtaag

230341. gctggaagct gatgtgtgga gactgagagg ggagtgatca gataaagtag ggccttgtgt

230401 atgaaagatg agattttatt aggactgtaa tgggaagcca ctggagtaat tgggaagaaa

230461 ttggaggttt tgttcgtttg cagcataagt tttaaaagag tactttgcat ttgggttttt

230521 agtagactgg gaagaaaggt gttggtagtt taaactaagt ttataacctg gagatgggga

230581 aaagtaaatg gagactggac attttttgat ggtactgcta atgggacttt ctgctggatt

230641 gatccagggg ataagaggaa ataggaatca aggccaaatt ctgggtttta tttgtttagc

230701 atttactgga atgtattatt ttatgggaat aacaggtttg gggcagatct gggggaaatc

230761 aaggattctt tgaaatggct atcagccatg caattcatga tgtctagttg gcagctgatg

230821 tataaggctg gtgctcaagg atacactcag gctagaggga aaagctagag atttatcagt

230881 gaacagatgg tctttaaaac cacagaaata gatgagatta tccattcagt gaatgtagac

230941 agaaaagagg gctcaagtca cagcccaggg tttagatgtt aggaggatga ggcagcagga

231001 gtgacggtga ctgacaagga gcaaaggagg acaaagtaaa caagaagata aaggcattga

231061 aaaaggagaa aataatctgt cagaggtttt tgcgagacag aaactgacta gaaagaatga

231121 aagacatgga tgccagatta gagtaggtta tggataaagt gggaggtgat agaggaattt

231181 gtaaggattg ggatcttaag aaagagtaac tgagaaatga ttgttaagcg tgggtaagtg

231241 tggcaggtgg ggagtggaga acttgaagtc aagggagaat tttataagat ggtgctctag

231301 ggtatgttta aaggtaatgt cctagcagaa agagaggaag actagccaga gagaacagat

231361 aattgctgga aggaagggga aggagagatg gttgagtttg ccctttgtag gagcagtgga

231421 tgccaggcta tgaatacaaa tgcgcttaat acatgtaagt ctctgtgcaa gacaatgata

231481 gtgaaaatca aagtgtgttg ttgacaatga agtgctaggt aaatgtgaca tgatcctgtc

231541 attctgcaat tacttctatt acttcttgcc tccctcacct cctcctcctg ctcctctctc

231601 acttccttcc aagtcacata tagtagtcca gtgtacagta ctagtacagt acagtttgtg

231661 ggtatatatt aagtcctgca tcacttaata acagagtgca ttctgataaa tgtaccgtta

231721 ggtgattcca tctttgtgca aacatcatag agtgctaata taaaaatata gatggtgcag

231781 ctttgtacat acctaggcta tatggtatat agcccattgc tcctcggtta caaacctcta

231841 cagcatgttt tcctattgaa tactgtaggt aattgtaaca caatggtaag tatttgtata

231901 tctaaatgta gaaaaggtgc agtgaaaata cagtataaga gataaaaatg gtacacctat

231961 atagagcact taccatgaat ggagcttgca ggactagaag tttcattggt gagtcaatga

232021 gtgagtaatg agtgaatatg aaggcctact atactactgt agactttata aatactgtat

232081 aattaggcta cactaaattt attttaaaaa ctttttcttc aataataacc ttagcttacc

232141 attaattttt ttactttata aactttgtaa ttagaaacac ttttagactc ttttataata

232201 accctgaagt taagatgcag acacattgcc tagatgtaca aaaaatatct tttttcttta

232261 tatccttatt ctataagcta tttttaatat ttcaattttt ttctttttta ctttttaaat

232321 gtctttctta aaaaccaata cacaaacaca cacagtagcc ttggattcat ggggtcagga

232381 ttatcaatat ctctatcttc cacctcgatg tcttgtccca ctgaaaggac ttcaggagca

232441 ataacatgct tggagctgtc atctcctatt ataacaaggc cttcttctag aatacctccc

232501 gaagaacctg cctaaggctg ttttacagtg attttttttt aacaagtaaa aggagtaaag

232561 gcatacacta acataatgat aaaaatggta tacataaacc agtaacatag tcatttatta

232621 tcattatcaa gtattattgt tctgtacata attgtctatg caaccctttt atacaactgc

232681 caatgcagta ggtttgtttg caccagcatc acacaaacac aggagtaatg cattgaccta

232741 caatgttatc atgaccatga cattagtagg ggctagacat ttttaagctc tatcataatc

232801 ttatgtgacc atcgtcatat gtacagtaca tcattgacca aaatgtcatt atgcagcatg

232861 taactgtata ttgtttctgt acctgctgag cagcaagtag aatgttcacc tcatttgcat

232921 cacagattct tttgaaatac aagttaagca gccagtctcc ttctcaggaa aatacaaaat 232981 cataaaagca tgcaaataaa gggtttctgg gacagctggc acttgctcca gagtaggagt 233041 tagttttaga gtttaatggg atagctggcc attttccctc aggcctttgg accgtatggc 233101 aatgattatt cctgggcatt gtgatcacat gcaaaggttg tataagagaa agaatctttg 233161 ctatggagag tttgttatta ggcttgctac acttctgcaa aatattttaa ataatatttc 233221 tttctttctt ttttcttttt tttttttttg agatggagtc tcgctctatc acccaggctg 233281 gaatgcagtg gtacaatctc ggctcactgc aacctccacc tcctgggttc aagcagttat 233341 cctgcctcag cctcccgagt agctgggact gcaggtgccc accaccacac ccggctaatt 233401 aaataatatt tctaagtgaa ataaaattct agacagcaga atgataagct tagtgtatta 233461 gaacatgatt tcagagtcat tccagattac acagaaagag atgggccaaa ctgtcactgc 233521 cctctgcttt tataatcaaa ggctggatgt attatctctg tggggagaaa gacatgttgg 233581 gcctagagaa gcctggccag agtatcagag atggacttag aagcccagca gagcctgttc 233641 ttctttgctt tttttactac tggattctgc cttcttgact ctgacttgac ctggtcaggg 233701 gaaggtgggc agacagattc agaggggcat atgggcacca tctctggtgt gagggtatgc 233761 ctgggttttg taggatgaac cttagagatt cttacaacat tagtgttaga agacatatta 233821 aacatctaga gtagtgattt tcaaggctag ggtgggttgc agatcaggat tgtggtgagg 233881 aggggaaagg atgtgttgtt tggaaaaaca tatgtaggat gcctgttgtt tccataatac 233941 aaattacaaa acacacactc accaaagttc cctctgctgc aacgggtatg acggtggtcg 234001 agtgttgcag gaagtcaggg accccaaatg gagggaccgg ctgaagctgc ggcagaagaa 234061 cataaattgt gaagatttca tgaacattta ttagttccca aaattaatac ttttataatt 234121 tcttatgcct gttttactgc aatctctgaa cataaattgt gaagatttca tggacattta 234181 ttagttccca aaattaatac ttttataatt tcctatgcct gtctttaatc tcttaatcct 234241 gtcatcttca taggctgagg atgtatgtca cctcaggacc ctgcgatgat tgcgttaact 234301 gtacaaattg taaaacatga gtgtttgaac aatatgaaat cagtgcaccc tgaaaaagaa 234361 cagagtaaca gtgattttca gggaacaagg aaagataacc ataaggtctg actgcctgcg 234421 gggtcaggca gaatagagcc atatttttct tcttgcaggg agcctataaa tagatgtgtg 234481 agtaggagaa atattgctga attattttcc cagcaaggaa tattaataat taataccctg 234541 ggaaaggaat gcattcccag gggtaggtct atagatagcc gctctgggag tgtctgtctt 234601 atgcagttga gataagggat gaaatacacc ctggtctcct gcagtgccct caggcttact 234661 aggattggga aattccagcc tggtagattc tagtcagact gattgtctgc tcttgaaccc 234721 tgtttcctgt taagatgttt atcaagacaa tgcgtgccca gcggaacatg gaccctcatc 234781 agtaattcta atttcgccct tgccttgtgg tcttgctctg ccctttgcct tgggatcttt 234841 tattgccctt tgaaacatgt gatctctgtg acccactcac tattcatata ccccctcccc 234901 ttttgaaatc cctaataaaa acttgctggt tttgcagcta ggggtcgcca tcacggtcct 234961 accaatatgt gatggcaccc ccggaggccc cgatgtaaaa tttctctctt tgtattcttt 235021 ctctttattt ctcagaccgg ctgacactta gggaaaatag gaaagaacct atgttgaaat 235081 attgggggtg gttcccctga tagttgagca agaaagtttt gtagaaaatt tgggtgaaag 235141 aaatgcagag atcttgttcc aggcattcat ttaagaggtg aggaaatgaa tcaagtctca 235201 gtggttgatt gacctgccta gggattcata gttaatagtg tagaattgag actatggctt 235261 ggcctccagg gttctagctg tgtgcctttt tgtactctgc taatgcccct tgcctctgtt 235321 caagtaagtc attagccata atgaacagtt ttgctgttto agtgtggtga aatccacagc 235381 aagatagctt tctagtgacg aaggttgtat acagggaagc ccatttgctc acttcctccc 235441 accccatctg ttcttttcct tagcatacag ggctttaatg atctctactt gctgcaatgt 235501 gtctctcaag atttaaaaac aaatggcaaa tttgtgcctc aggagtcttg tgaaaacaac 235561 atattacatg taagaaacaa ataattttat tttctggtta tttttcacac ttcttccaaa 235621 tggtatcata ggatgctatg cctagtttcc ctttctctag tataaactat tggttttaat 235681 gaaatatcat ttattacaga tagtagggtt ttatgcattt ttttcattca gaatcaaagt 235741 ggaatgtgtt ccaagtgctt gtgtgcatag tgaagttttt tttccttttt gaaattgttt 235801 cttgtattat gttgttgcct catgcctcca tcctgtactg acagacgggt ttgcttgctg 235861 ggatgtttac ttcaatgcag ccaacatata ctgcatgcct actgtgtaga catctagaag 235921 gatgtaaaaa gaatgaagga tgtgagttaa gctgactatc atttaaactt tgggatgatg 235981 ggataagaga ctggaaatta cttgcttcag atgacaggct acatctattt tccttctaag 236041 aggactgtcc tattaccttg tcactgtcac cagaagctgt cggactttca agctaagatg 236101 ttctctactc ctgtcttttc tagcctggca actgcctatc tttgtttcaa agccctgttt 236161 aattttaaag gagtgaaaaa gactgcggtg tgtgcagttt tctgtgttgg agagattggc 236221 agagtgattt tccagaacca aggactgagt ggagctcaag tcttacttgt tatttgatcc 236281 ataaagtttg gaaagttcat gatccttaaa aagaactata taagaaggct tttagttttc 236341 tttaaagcca tagtgatttg ccaaaaatat atccaaaaga ataaccagaa caggacattc 236401 ttctctaatt aactataagt tcccatttga tgtattaaga tttaggtaag cagggagaac 236461 aagagttaaa ataattcttt gtcttttaac tgtgatcttt cccatccctt cctttgctag 236521 ggtaggactg gtggttggag aattggatac ataagggaag cttgtggcct cagtccaaga 236581 taggacaata tggtagttct ggaagagatg taggaattct gagtaatagt ccaagatacc 236641 tttctcttta tcctttttcc tgttttattc acttccactt tgatgcattc ccattccaca 236701 atcagtatgt tttaccttta caatagaagg tgatacagac tgcttaccat agtttctctt 236761 ataccaaagg gctacagctg ttctccattg agaggtttag ccaatattgc attagtagaa 236821 attctgaggg attttcttta actttttcat tgacattgtg tctgtttaaa gtgcaagtga 236881 atgaaggaaa aatacaagag agtacacact catatgcaca tacaggtaca tatatggtgg 236941 catatgaata gaaaaagaaa tgggagggaa ggtatcaaac tggttttcta tagctagaat 237001 ttgatggatt tttgtgtttt tttgctttat acctttagaa attgttaaac attttttgag 237061 gcaaataagt tttactttca taatcagggt aaaaaaaagt tttcctattt gaaaaataaa 237121 agttacaggg aacttttaga acattgcaac tattctatgt cttattgtaa tggtggaaat 237181 aattcatttg tccaaaccca tacaatatag aaaacaaaca gtgaacatga actgtggacc 237241 tcagtgaata aaaaagtgat caattttagc tcatcagctg taaaaaatat agcctcctat 237301 gttaatacta ggggaacctg ggaagtggga gaggagggac tatatgggaa ccctctgaac 237361 tttctgctta cttttttttt gtaaacataa aactgctcta aaaataaagt ctattattta 237421 aaaataaaag taatatacaa tattgttaaa tttggggtgg taactaaaca tgttgcttaa 237481 ttgcctcctt ttttgttagt tgcccataac agagcagttg cttacgaagc agcacttacc 237541 tacagcagca cttccttatg aagtttctga taataatgat attttcatca tatatatata 237601 tgtacacaca cacacacaca cacacacaca cacacaggtg tcagctttcc cagtggaaca 237661 aaaggagctg ggaagattct agtgactgtg gttacttgag ggtacttctt atattcttag 237721 tagttccaga cacttgctta tggaaaagag gaaactaatt ttcatggagt gcccactctg 237781 tgttgggcac tgcggtaggt gtttcgcatg tcctcatgca gcctttaata caggtaccat 237841 ccttacactg aagatgagga agcagctgag caagatcaca agctagcaga gacaaagcct 237901 agaattcaaa tcctatgtat ttttttaaaa aataatcata acaccttgga gtgcccttag 237961 caacaagcat ataacaaagc aacagagcaa taacagcccc tgcaagttta gttagaaata 238021 ttttgaaaaa tgagaaaagt actttaatag ctaattgtat ctttggattt attatactca 238081 aaacgatgac acaggttagt ttgttatgta ctaggcaaat ttaatacctt attttatata 238141 ttttcttaca agatgctatt ttgatcctat gaagccatca tttgacattt tggcagtaac 238201 attaggcatc taatttcact ttctttgttc ctgtcaaacg atccccacaa gtacaaagtg 238261 ctgtgtcaga ctcatgtgaa aactttgaag agtttgaaat aagacagctt aaagtgggaa 238321 atattctctt attagtgatt ggtgtgaaag aaggcagtga gaatgtgcac cagaaagtga 238381 tctggtactg cagcctagga aaataaaggc agaaaggaag ggtgttagga acaagtggca 238441 cagattggag aaagcagaag ctgctagaaa gacttttgaa acaaaaagac gtctttctct 238501 cagaagaacc agagtgtgtc aggcacaatc tggaagtaaa acccacacat ctatgtgcgt 238561 ctgtgcgtgc atacacatac acatgaatgg cgaatggcag tttgttgcaa aatgtcaaat 238621 gatggcttca taggattaaa aatagcatct tataagaaaa tatataaaat aaggtactaa 238681 atttgcctag tacatagcaa actaagctgt gtcatagttt ttgcaccatt gcaaaagttg 238741 gtacctggaa ccctaatttg taaaatttat taatccttct gttagtgtct gagttgaatg 238801 agggcctgaa tttacaagtg aagagataaa acatttccta agttgttgtg tggatctttc 238861 ataggaatgc caaacaacct attgctaatg ttgcttttat tggagaggtt tgcacagtga 238921 caatattttt cctgcttgat tttactgaga ccaaagcatc actattgtgc ttataagaaa 238981 tgttcttctg ttaattattt accttgcttg atgtaggtac atgagataaa ttttgataat 239041 tccttaaatt tacattttct tcactaagag tgggagctaa tgtttggctt gaggtcatat 239101 gaagttgata caaccaaaat tttgcaccca atactgctag ttctcttcta gctttaatat 239161 tttggttcac tagttcatta gtctcagtcc ctttttcctt aaaaaaattc acaattatag 239221 tttaatgtaa ctcatatata cttgtcacac aagaaatgca tatttaaaag tagtgattta 239281 tcttgatttt taaaaaattt tgcagcttta ttagaaaatt aatgacttga ttattttatt 239341 cattaaaatt aattgatgat aatcttaagc actgggaatt agctgtgtcc atctcagtag 239401 gttaaccttg tatatgtgag atatattagt aaagctctag attttaagga ttaatgcttg 239461 ttaggaaaaa caatacatct aatcatattc ctcaataaaa agcatcctgg aaagcacttg 239521 atctagtctc cttagtgctg gggctgtggc agggaattct ttggcttgag acccatggca 239581 aagttccctg gggcagagac ctggttctct agaaatgaag acacataatc tgtgcatagc 239641 agagccagga gcagtgtctt gggaattttc tgaactggaa gtgaaagtcc acctgatgat 239701 tagagggagg aaaatgcttg taaaggcatg ctgtagggaa ggtcaatagc ctggaagaaa 239761 ttcagatgct ttttatgcta ttcctgcctc agataatgga gtttttgact atgatctata 239821 taatgtaatg taatttttac tgatatatat cccattgtca aacttccatt tatatagcat 239881 ctttaaattt ttactaggga aaaggtaagc attttcaccc tattttcata gagctgccaa 239941 gttatgactt tggttttgta atttaaaatg aaatggatta aaaaaataaa ttatcattac 240001 tccttggagt gtccttggta acaggcatat aacagagaaa cagagcaata acatgccttg 240061 caagtttagc cagaaagatt ttgaaaaatt agaaaagcac tttaatagct agttgcatag 240121 gcacataata ctggagcctg gagggaggtg acctgtggaa gtacagttag gattgggaat 240181 taggagaggt aaattctaat ctgcttttga taaaccctga ccttcgtcaa ggaatttaac 240241 ttcccatcat ctcaggtggc tttgattggg ggtggggtaa ggagaaatac actttttagt 240301 ctacaaaatg tagggtttgg cctaatgata tataagctcc ctttcaacta atactgtgtt 240361 cgtctggaac agatggtaga aagagcactg gccttagagt catgaggtag gacttctaaa 240421 ttcctgtgct gggctgttgg tctcttctac tctgaaatga aatatgaagc tagattattg 240481 tctcagaatt tctagataga aaattatctg ttttctggct gtgttcatgt ggtatttgca 240541 tatatttgca aaaagctggt aggaatgatc aggtttcatt tccaagctcc agatctgttg 240601 ttcatgtgat cttaaccctc tctgcagtca acaaatgaag gataagaaaa tctcagtttt 240661 taaatcgtat tggaaagttc tttcttaaac ttctcatatt agaaagtttt tggctgcaaa 240721 tcacagatag cctttactca gatggtttaa acaaatatac aaacaagaat gtattgtctc 240781 acacagtaag tccggaggaa aggtgaggct tcagatggtg aagataaccc ttccccatct 240841 ctgtggagct ctctccttag ctctggcttc attctaaaat agtgaccctt aggttagtca 240901 caagatggca gcttgtggca aaatatctag cgagagagag agaaactttt tctccttagc 240961 acttgccaca ctctaacaaa atacttattt tacacgttcc ttttttgtga ttgtctctct 241021 ccaccagata aacatcaggt gggcaggatt tttacttatt ttttttcttt tgtttcagtg 241081 ttgtgtctcc agtacctagc acagtgcctt gcacagagta gtcactcagt aaacatttat 241141 tgaatgaatg aatgagttct .cttaactcat tacataagcg agtattgcat tgcatatatt 241201 cctgagtctt aaaactatgc tttctatatt tttgaaggca tttaatgata gatattacac 241261 tatgtaaatc tggttaaaca tttttggaca tcattgtttt tattccactt gttttaaaag 241321 tttaatttta cttttcatct tctaaaacta ttatatagaa atattctggg ggaaatttaa 241381 atcagaaaat tgattaagtc ccttatttga acttatttga attactcttg ttttggtttt 241441 cttttttttt ttttaagatg aagtggtagt ttaaaactac aaagaaagaa aatatccaag 241501 tttacatgta tggcatatag gcaggtagaa attgtttttg ccagctcact tttctggtgt 241561 cacttacgtt tgaatacatt cctagcaaac cttctcataa gacttgtagt acattgtatt 241621 attcgtatca caggtaatag gcactactca atgctaacct tttaataggc atgtacattt 241681 ttatttcagg taatctaata tctgtatgag gttttctgaa aaaataaaat gagaattttt 241741 ttgtctcctt ggtgacacta ttatgtcact aagttagggt ggcagtttct agccattaat 241801 agctgttctc ttaagctctc ctagaatagt gcattcagtt agttttatgt gaaaggacac 241861 catcttttcc aacagtaatc tattctgtgt attcctgctg gatgaacctt acagaggccc 241921 accttttatt taactctcct gtcttttttt atataaaata ataattaaac tccataaaaa 241981 cctgaagaat gaggacccaa acctttgtct ccaactttgt ccccattact ttacttcaaa 242041 cattttggtt ttcaaccaaa ataaactaca tattttccca tctgtgactc ttcttcttcc 242101 cccaaactca agttccttga gcttagaatg ctgcatctca ttataacata tccataggtt 242161 cctccagagc agctcatgtg ggacctgtac tataaggttc cacacttggc tccattggga 242221 gttctctctc ctatttctcc attgctctaa tatttcagtt gttcagttgt tacactctca 242281 tgcacttaca aagatctgct gtaataaagt tatttatggc tcttctcacc cacttaagag 242341 gagtagtttt gctttaagat ccttctttga actgccagtc tgtgctgttg ctgaacatgt 242401 tcttggctag cttcaggaaa tgtttgaatg gagacagact cattttgtta gaagtagctg 242461 atctgcacat ttccatcaca ctaagcagta ccccagattc taaaatggga aaaacatatc 242521 tatttattta ttgaggtagt aagaacaaaa ggaaaaatgt aaaaacctgt cagtcaccca 242581 gtgccccatg ccagagtagg ttaggaccag gatcagggaa atgggtaggt gtggccaacc 242641 gtaggtgtca tcagtcacca cctggttgtg ggcccatcac ttccctcggt tttatgaggt 242701 aattcacttg gaaaggatga aaatcacctg aataaccaaa gtggccccca gcatcctaat 242761 gttggggctt ggcctctgta taggctcctg ccctccacat caccccactc tccttcctcc 242821 cttcaccctt atcaggaaca gtttgctttc tggttggtcc agtccatttc cccaaagctc 242881 tcctgtgtgg agtagaggca agcagggcct gattgctcat tattctcttt ccttttaaga 242941 tcccagcaga agagtttttg ggtggcaaga atacttattt attttggttc aactgcttta 243001 tcttacttag ggaaggaggg tttgtaattg tatatatcaa aacatttctc taggcaggtt 243061 atgccaagca atctggaggt gttcttggat gcttgtctac tccagagcta acctacgcat 243121 agtatgaatt ttgcttatat tccagaagga gtcaaatgtt aaaagttttt tggcatttgc 243181 tatatctttc catatcttcc gaggttagat aatcacaaag agaaataggt ggtcaataca 243241 tattagctga ataaatcaat aaatactttg ttaaataagt acctgcctta gaagagagta 243301 gaaagcaaag gaattaaaaa atattttaat taatttttat tagctacatt tataatataa 243361 aagaatagat tatccagata aaaaattaaa ctaaataatt aatattaaat aaacagtaaa 243421 ccaccaatct acccatactt tatcccctga gctctgtttt cttccacatg ggtaatttct 243481 tttcatagct tgagtacatc catcacctct actttctttt taaatgcata cagttctcaa 243541 cttgatgttt ttccccatag acatgttaca atattggtag ttagagaact atatttttaa 243601 atatctacat gatttttatg ttatataaat gtaccatatt ttatttaacc agagtaaatt 243661 ttatttaaca caataaatga cagtttaggt tatttctaat attttactgt ttatgaagaa 243721 cattgaaatg accattctta ttaatgtgtc tttgcttatt tctgcccctg tttcttaaaa 243781 gataaattcc caggagaaat gcaggttcaa gggctacgaa aaatgtaatt tttttaggtg 243841 tttactagtc ttccttccca ccacaataac tctgacctca aagagtgtcc aagtgtattt 243901 atttgttcac atccttgtca gtgttatcat tggattaatt ttattctgag tttcatgcat 243961 taattaacgt ttatctctgc cttcctccca ttctgtttgt tttgtgtgta tgttgggggt 244021 ggggtctgtc aaggcataag catgttttct ttttttttct tttgacagag agtcttaacc 244081 tgtcgcccag gctgaagtgc ggtgacatga tcttggctca ctgcaacctc tgcctcctgg 244141 gttgaagtga tcctcccacc tcagcctccc aaatagctgg gactgcaggc ttgcatcatc 244201 atgcctggct aagtttttta gtagaggtga ggtttcacca tgttggccag gcttacctca 244261 agtgatttgc ccgccttggc ctcccaaagt gctgggatta caggtgtgag ctactttgcc 244321 tggcctgagc cacagtgccc agccagtttt ctcagacttt aaactctgca gtgtttcagg 244381 tagaagcctg gcagtatggc ctgggaacta gacctgactc ttggcccagc ttggctgttg 244441 gctctctgtt gctaccttga ataagtgcat tttatttctt tattcctcat tttcctgggg 244501 ggtaaatatc aaaagtttaa tacctacttg actttttttc taagcctctg agattgaatt 244561 ggagcagcag agggctagtg aggggaggac acatcccaaa ttggatgatt ttcaacattc 244621 tgagccacat tagtcttatc tgaaaaagtg catcaaatgg gctaaatgtc tttcagtgtc 244681 tgattaaatc tgccaatcaa tgaatctgta ttcaaagtga tatgaaagaa acaaatgtcc 244741 catgctaata acactaagag gttcctattc catctagtgg gtttcattgg ggctttgaaa 244801 taaataattg aaaattgata taattttatt tttgcctatt cgttggctga aattacgacc 244861 atccacaaat accttcttat gtgttctcct tcttgtccct tttcttactc tgtttattga 244921 tttgtgggac acataaaacc cactttaaat tgtctacttc cagtttcctc attgattgag 244981 tttagatgtt tgttcttgcc aaatctcatg ttgaaatgtg attcccagtg ttggaggtgg 245041 ggcctgttgg gaggtgtttg ggtcgtgggg gcggatccct catgaatggc ttggtgctct 245101 tacggggcag tgagttcact tcacatctgg ttgtttaaaa aggagcctga tacctcccca 245161 aatcctcttg cttcccgagc ccttgcttcc tctctcatca tgtgatatgc tgctcgctct 245221 tcacctcctg ccatgacaga aatcttcctg aggcctcaca agaagccgag cagatgtgag 245281 tgccatgctt atatagcctg tagaattgtg aaccacataa acctcttttc ttttgaatta 245341 cccagcctca gtatttcttt atagcaacac aaaatggact aatacactta taattgttac 245401 tttatcttat cttggacaaa gtggtgttag gtttttacac atgacattca aacattaatt 245461 tagggaccac aaacttagag gtccagcaat aatagggtat aagagctctg cgctcttggg 245521 gattggagag ggtggggagc catagcagtg atgcttgttg aaggggccag ttgtgtagct 245581 ccagccacat aacttttacc acatcgtgaa gcacaggatg gcagaggttc tgatttttat 245641 agaaaagcca gagtgtttat ttatgtgaaa atttctgatc tttaaatacc tgacaaagat 245701 taaaaaatac tgcacagggt acttaaacca agtctgcggg ttggatctgg ttctactgta 245761 aatccatgta tggttagaac atcgtcttcc ttttcttatt gatactgtct tattgttaac 245821 aaacttatct catgctgaat aaaatgttgg gatacaattt cagtttccga catgtgcttt 245881 tagaaataaa tgatactttc aaagcaaagc ttttaccatc tttccataat ctgaaatgtg 245941 tgtggaaata aaataatgcc tttttagtta tagcattaat atataacatt tcacccactt 246001 atgaaaggaa aactcctaat gacatcctat aggatatttc tttgcttctt tttaaaattc 246061 tgtgacatct ataatctccc tttgtttgtc agttaataag aaaatgagaa tggatttatt 246121 ttttatcagt gtattcaggg tgaactgaat gcattgtagt gagataacca atctacagca 246181 gagtgcaatg ctagatactg tgctccttgc agtgatttat ggaggatcct gtaatgattt 246241 tatttttctt gttcatgcat gcgttattca atcagcactt aataggcatt ttctctaaac 246301 tcagcactga attgagtgct atgggcacag caggagtaag tgtaaataat gagtgagtgg 246361 gggatataga caggtgggaa taggtcatca ggttattata atactgtgac aggacaacac 246421 tgctgagaga aggttagaaa aggcacctca cttaaccttg ggggtcaggg aacacttcca 246481 aagaaaatga taactaagtt aagatctgaa gagatggtgg gaattggtga ggcccagaag 246541 ctgtggaaga gggaacagaa aggacaatgt ctcctaattt tgaaagacca tgggggattg 246601 aagatctgag aaaagcacca tatggctgga gttccaagtg tgatagggag tcgggagctg 246661 catggagacc tctccatcag gagcctgttg tgcgggctct tctaagtcct gttaagcagc 246721 tgttgagagg ttttaagaag agaagtgact agatcagata aaggcatttt tcaaaagctg 246781 atttgagcag cagtttcctc tttagctccc cctttactta ttactgtctt cttaaacctc 246841 tttagtccag gtggtgatgc_ tgcaagtgaa cagttttcac aacaatcagg atatatctga 246901 tgtcctttta gtcttcttag cttcaggttt ttctgccttc caacacctgg aaggatatga 246961 agataaaggg aaaccatgac cacagcaaaa aaactaggaa tggatgcaag aaaactaaga 247021 caaaaggaaa agcagaaaat atttatttta ttatgaaaat ggaattgtac tgtgtcagga 247081 atcaggaggc cagaatttga gacctatgac caaattcttt tatattttat tgtcctcaat 247141 ggtcaaataa agggttggat tggtgtgttt gaaggtgacc ctgagtttta caattctgtg 247201 agggttattt cagttgtgca tggtgaatca atcaccctgt gtatcagtca aattacaaat 247261 atattcagtg cactaagatt ttatatatat gtgtgtgtat gaatgtgtgt gtgggtaatg 247321 tacatgaaac aagatgaaaa cttattagaa agggaagcat gggtcagtag aaggttgagt 247381 gcatttgaga agatgatggt aatgctaata atgggtggat gtttgccata gctctcagga 247441 gctgcctgtc tcttatggaa aggcaggttg tatgagcagg agctattgtc aataccagtc 247501 acaagtgtac attgcagaga ctgtcccctc aactgtttgt aacccaaact gtccaggagt 247561 cagatagttt cttacctaga ggaatgtatg ataaggttac ctctttctcc aattcctctg 247621 tttgacagtg cgtacagaga tgcaagattt ctggagaatt taaggccata atagagaaac 247681 ctgtttttct tcccctttgt cattttcttg aatacctgtt ttttttttaa ttattatgac 247741 aatttgaagt taccttgcta atttatttat tattattatt tttagagaca gagtttccct 247801 cttctaccta ggccgaagtg cagtggtgtg atcatagtca tagtgtaacc tcaaattctt 247861 gggctcaact ctcactctgt cacccaggct ggagtgttgt ggcgtaatca cagctcactg 247921 cagcctcaaa ctcctgggtt caggtgattc tcttgcttta gcctcccgag tagctgggac 247981 tacaggcatg tgccatcatg cccagctaat ttttatttgt tatagatatg gagtcttgct 248041 atgtttccga ggctggccct gaactcctaa gctcaagctg tcctcccacc tccacctttc 248101 aaaatgctgg gattacaggg gtgagctgct gtgtctggca aatcttttaa tgttattatt 248161 ttttgtattg aagtagtttc cctagtatca aggagattta ggatgtcttt attttcagaa 248221 aaagttggaa ggagaataat ctcaagctta ttaaataaca ttttgctata tgtaactttg 248281 cataaaccat tttattatca cagacttcta aatgctgaac acttgcgata agtcactcta 248341 ccctttatag gtatgtattc ctgtcttgct tttatgtatt tccagatgta gaatagcctc 248401 tttcaatgct gcattagctg gaataatgtg aagcagaaaa gttaaacagt taaaaatgaa 248461 agaaatgagc ccactcagag gctgggactc cccagtcttt gccaccatat ggttggaagg 248521 ccttagtgcc ttttcttaga ttaaatatct cataaacacc ccgaacattt gagtgatgct 248581 agcattggcc aagcacggtt attagcagcc gagcattacc ggatactgac aaggaggaca 248641 ggtacaagtg atagagaagc aaattgggac tcagtgtatt agtgacattc atgtaagtgg 248701 cagagctcgc tcagggctga ggtgaactta ggtgctcaca aggccactgc tgagtagagt 248761 cagcctgagg gattttaagg cttgtccagg cctaggagga tgactgcctg aaggtgaact 248821 gacactttgg gtaacacagg ctctgggact gtgggccttc caatgaactg tgctgtactt 248881 tgtagttttt tcagctttga ctttgtttca gtcaaatgaa gtagtggtat gtttgaaatt 248941 ttaattcagc tccaaccaaa atctgtattc attttttatg gtcttttctt tctcttcctt 249001 ctgtgctcat aatctgtttt cattatgatc agatctgctg attgtatatg tttatcaaag 249061 cactggttct aaggtaattt acagcaaatc ttactctttc acagatttta gaattgtagt 249121 gggattggaa aggccatata attacgacct tatcaacagt tcattaataa tgaaaaactt 249181 tgttggctga cattttttgg gcttttcaac tgaacgggaa aaaactgcac acatcaaaat 249241 accatcaaat tttcagaatg aagaatttcc tttgccttct agctcaagac tatcactttc 249301 agtagaatct acctcagtag ctttgtgtgt gagagagggg aaacccaagg aagaaaagac 249361 aaagacagac actagataca tgaactgagg gactgactta gctgtttctg ttgatatgct 249421 tgtagagcag caagtaggtt gaagtgtaac taaatacgta aacacacaaa cacacacaca 249481 cactcacaca caccataaac atgctacccc tctccctctg tgagagccat agcacagtga 249541 tttttaaact ttaggatgtg taaatgttaa atggacagtt tggttgaaat atggaatata 249601 agcttcatga gaacaagagt tttttgtctg tgttacctct gttttatctc cagtgccttg 249661 tggttggcat gtagtagatg ttaaataaat atgtattggg tgattcgtgg gttccatcct 249721 tataaactta tatttggtag ctttgggata ggactccatg aatctgcatt ggtatcaggc 249781 acaccagttg actttgatgt agttggttgg agggccatac tttgagaagc actgcatgat 249841 gagcctggag ctgcggctgt tgcgaatggt gaatggtctg tttctccata aagggaggtg 249901 ggttctaatt tgcttaagaa tatgctgcag aactaccttg ttttgtggag gagtctgaca 249961 gtgctttacc tcttgaccac agtcttacaa agttgagtat cttatgtgcc tttgggtgct 250021 gggacttgta gccatggcaa aggagatgtt ttctgacttt aaacttatct gtagaagata 250081 cagatgtgta aatcttatgt gtaaaagcat acaacaatag ctattcacat acattcattt 250141 aaagagaggt tgatttaaat ctattcagac agcaaggtca ggcacagtgt atcatgcctg 250201 taatcccagc actttgggag gccaaggtgg aagaatcact tgagtgcggg aattcgagac 250261 cagcctgaac aacatagcaa aacctcatct ctacaaataa ctagaaacaa acaaacaaca 250321 acaacaacaa caaaacatta gccaggggtg gcggcaggtg cctgtggtcc cagctgctca 250381 ggaggatcac ttgagcctgg gaggttgagg ctgcaatgag ctgtgattac accttgcact 250441 ccagcctggg caatagagca agaccctgcc tctaaataaa tacataaata aaatatacgt 250501 aaatacaaat ctagtcaaat agtaatagct aatatgatat gaatggttat tcttcttaac 250561 cagaaaacat aaggggcttg gtgcgaaacc actcatcttt tttttttttt caatcacata 250621 ctttgtagtg ctcttgttaa ctgtacatgt aacccatgtg taataaagta taaaatagtt 250681 aaaatgaagc aaactgccta acggctttta aacctagttt ttatggccag accaagatta 250741 aaaaataaaa aacctgttat caggtcttgc agaaaccctc agtccctaaa ttgtctcttt 250801 tcctcctgaa gacagtacct ggattataat caacaccatt cccatccttg ttgctaagta 250861 catttccttt ccccagaagt tactagcaag atgtttgcat ttaagaagag ccacatgtct 250921 agcatttatg tagtacctgc atttgtttgg atctttccca tcacaaatag gaccaagatt 250981 aactagagca tggaacagca gaagagggtc atttacaggt tgaactagca gtgaatggag 251041 acagcaagat tgaaaatgtt ttgcactgag taaattttaa tgcaggaaag taactattta 251101 gaaaagaaac agatttaaca tgttagatta atatgtgata tgagagcaaa ttacaggctg 251161 atacagggtc tacagtgtac caggatagaa aaagagatcc ttaatataca tatttccacc 251221 agtatccaag tgaggaggga ttagaagtga agaatattac tgcagttata atgattcatt 251281 attgtattat agttccatat tgtataaaca cctgtatgct ttttatttaa tagtgttgtt 251341 tcagttcttt agcaaattca cttgtaataa aaacttttcc agatatctcc tttttagtat 251401 aaaagcaata tatctttatc ataaacaatt caaatgatgc agaaagatat atgtaggata 251461 ttaaattatt tctatatctc ttctcagcta taactataat ttgatgaata gattattcct 251521 ttttaaaaat gcagtcaatt ggtggtgatt tggtagcaga ttaactggtt tgaatattaa 251581 tgttggtaaa aataacaata catttgtgaa aaaatttaaa tgctttgaac caggtaaatt 251641 ctactaggtt gaaccacgta caattgctgt gttagtaggt aaaaaatgtc aaatattggc 251701 agtttcatgt ggtcaagctg tagtattaga ggagtgtgtt ctttacagtg atttagtaac 251761 cagttgatgt gggcatgtga gtccacaatg tggaagtagc ctgtatctca ccgctctttg 251821 ccagtagtca ggtgacagat aaataggtat cgatgctaag gaagggggaa atggtttagg 251881 ctgtaatttc caatatcaca tttcagttct atgatgttag ggaaattaga gagaagcaga 251941 gcaagagaag tgtgtagtgg gattgaattt ttgcccatct ccaaactgaa aaactcttaa 252001 gaagcaagtg aaaacagtac accttttcgt agatataaaa caacttacat gatattttaa 252061 aagtattcct aacctgttgt attacctttc caattttgga tgacatctgg tgaacaaaaa 252121 acatctctaa atcctgaatg tgattttagc taaattaagg attacatgac accacattta 252181 ttttaacctt acgtttagag ttggctatga cctctttcct ccataaccca cagttgactc 252241 tttgtacata tgtgtgtata aagaataaaa agcaaatatg gggtccaaca tttaattcta 252301 ttttttagcc ctattcctct attttttcat tcattagttt atggttctgt gtgtggagtg 252361 tttattgtat tagatatcac taaggagaag gtccagattg atcacagtca cagtgtttat 252421 cattgctctt ccagtgttta ggccaagcag gcagcatgca ttatagaacc atgaatgcac 252481 taacccggag ctgcgtatca gtgctcagcg tacgcacatg ttctttctct gctagactgt 252541 ctcctcatta cagacagtta aacaagcaat cctgtctctt ttgtgcatgc aatttttaag 252601 tcccctcttt atatttcccc tcagaatatt ttagctatga aaatattcag actccactgg 252661 caagtaaggg agatggaact tagtagttaa aagtagtttt actatttgta gtaaaagtaa 252721 atttcaacag ccttaaagct gtcaagctgt gggcttgaaa aaaaagttga tgtttgttgt 252781 ggttgtagct tgagatatag ttgggtcctt aggtttcatg agtagtcatt ctgggaaagt 252841 caggcagcaa tccctctact ccactctgct gagaaagaac acataagatg aaaggagcct 252901 gtgaatgtct tttttctccc agagactaaa ggcgaagtga tggcggatgg gctgtgtgtc 252961 tttgtaatct cttttttcct agtaggacat caaataatga tctagaaaat tatctcaaat 253021 attaaaggtt tttttcccct ttattaacaa tggttttgga aaaaaaaaac acaccactac 253081 agtgggtatc tgataaaatg aacttactct gattttctgt attatctcaa aatttatttt 253141 aatcatgatg ggactagagt ttggatgaaa ttcatttctt ccaagttgga gtgaaaaatt 253201 aagttgttta ttctcaaagt gggatgccaa ggtttgagta tggctgcgaa tatgaatctg 253261 aatccttctg ccaacctaag ggaaggctcc ttgcatccct ctatcctact gggactttgt 253321 cagagcacag ctacctctat gagcaaatgt ttttctgttt ttgtatagtt ttgacaccac 253381 agcccctaaa ctattgttat aattttcacc cttaattcta attacaagtc ttttgcatca 253441 tgtgcaattt taccttttca aatctcactg gtgaaataaa tttaaaacat tgccatatgt 253501 ttacctaaaa tttatgatga aaccaaggat gcttgaatta ctaatgctaa tgttacagga 253561 tttttgtaga taaacaatga cagaataaca tgtcttgtgt ttatgatatt attaggatta 253621 catggagtat gattttgaca gtgcttgtct tgatgaggga gacacactgg ctctagaact 253681 tgtaggtgtt aatctctgga ctgacttggc agctaggaga ctcccttgcc ttgctaacag 253741 caggaactgt agtatctggc acctcactgg gaccagtggc tgctgccttt ggcagcctca 253801 aagttagtca tgtctgtcac ctaccgtgat gttggtacat atcgtaggct gttttctgtc 253861 cattaatgcc atttttctgc catcagcttt gaaattagtg gctctgtgct tttccaagta 253921 tgaattcatt atgttaatct taaaagcaag agggcttgtt tcaaattcag atgttggtat 253981 ttatttaact gacagtgtgt ttcaaaagtt tatataaata tgttttgaaa tctaaaatct 254041 gtcataatta ttgagattta ttaggatgta atgtggaggc tttcaggttt catctaagtg 254101 gtcaaaaata taatatgaaa aatgacttga tgcttttcta taatattagt cactttcaag 254161 aaaaaacatt ttcttcttaa gatgaatgtt ggcaggaatt tgattttact gaaattgtgg 254221 gacaaacaca gtaggaaatg atgggtgtga agatattact ttgagaagtg agaaacaatt 254281 taggtgtaag tggtaagaga agaaaggcag taattggggg aaaacggtta aagaaaatcc 254341 tgtgtcaaag cgtcctctgg gtatgagatt ctcactgaag tggaagcttt aataccttta 254401 tggagttgtt gccaataagg atggatcatc tctgaatttg acaacctgag gtattaactt 254461 gaaaaatgga atttgacaag attgcaaata atgttcaata atatgtttcc aaaacttgct 254521 tcacaaagcc atcjtgccttt cttacaacat gatattcagg ggcccttaat tcatttgatc 254581 tgaaaagttc ccgtgcaggc taggtgttat gtaccatacc ttgccatcat ttaaaaatac 254641 cctgctgtgg tttgaaataa tgatctctga ggatgtgtgc acctcagaag actggtgcag 254701 aagcaagtat cacttttaaa atgagcctat gcgatcccca gattaatatc tgaaagctag 254761 ctacctaata aagttttaat tgcttaaggc tactgggcta gttgaataat tgaaagaaag 254821 aagattgtaa attattagaa ttaacaatac taaactctgt ggtaaatgta tagtgattgt 254881 ttcttcaaag ttaatgtgct gtgattttac tgttattgta attactttct cacttgagtg 254941 ctggtttata aagctcagat aaaataagcc tgtagatatt tttacaataa ggtttttagt 255001 gtgcaaaact aagtttctcc tggcagatat gtgtagggca gaagagaagt cctctctacc 255061 atagttagtg tctacttttc ttgcctggga atatacattg ttgctccaga ttcagttccg 255121 gagggaacac ccttcttatt gccttcccca ccgatcagtt atcagactgc cttcttttga 255181 ccaatatatg tttataaaag tttatatttg gattaaggat ttaatatatt gttatgaaac 255241 aggtttgctt ggggaagaca atggaaattc atagcagtaa caatagttct gataacacga 255301 gttcaccttc gtggaggtaa tactgacagt tagtgtacta ctaagtccta agtactttat 255361 ttttgccttc tctgatgact gtccagtgca gactcatttg catggtaatt gtgtatctaa 255421 aatattattt tattttagtg aaatattaaa taattgaaat ttattttaat atgttaaaac 255481 atgggtaaat ctcttttatt ttttaaaaga ctttacattt tagagcaggt ttaggttcat 255541 agcaaagttc attggaaagt acagagagtt tccacatatt ttccatcctt cacatatgca 255601 tagcctcccc agctatcaga atccccaacc agtgtgatac atttgttgca gttaatgaac 255661 ttggaataac acatcattac ccaaatttca tcatttacat gaaagttcac tcttggtgtt 255721 gtaaatctct ctttaaagat atggccttgc tgtattatta tttgccaagg gatcaaggac 255781 ctgctcaggg ccaccagtgt cagcaactag attctgaata aatatttgat taataaatga 255841 attactacaa gttattgata gaatataggc agaatgtttt tttgtttttt ttctcttcag 255901 attttatagg ttcttaacaa aaaaccaaaa tgaagacata atgtttttaa tgtaatggta 255961 aagaggaaac ttctgtgttt tgaatactct acttgaattg tcattgctgt aaagagaaat 256021 aattttgatt atttttgttt ttactcaggt atgaagaatt tattctcaaa ttaatactca 256081 tgcttatgag tgtataaatg ctcatatatt gatttaataa aggtttctgt tacttgatag 256141 gatgggctac ttgcattgta caattttttt ttaacatttt cccctgtctt tcacagttct 256201 tttattctta cacagagtta gaaagatgta agactaaatt caccacctaa atttaataaa 256261 taatattttg taaatatatt tatatcattt gaccccataa ttctattttt cacaattatt 256321 ataaggagat aatccaaaag gcggaaaact aagtgcccag tcacgtcttt tgtggtatta 256381 tttataaaca taaatcttaa tctaaaattt ctttaagatg agcagtgttg caaagaatct 256441 gattatgggg atgtgatgtg tctcattcct tttttttttt ttttttttga gatagagtct 256501 cactatgttg ccaggctgga ctgcagtggt gtgatctcag ctcactgcaa cctccacctc 256561 ccaggttcaa gtgattctcc tgcctcagcc tcccaagtag ctgggattac aggcacgtgc 256621 caccacacct agctaatttt gtatttttag tagaggcggg gtttcaccat gttgatcagg 256681 atggtctcaa tctcttgacc ttgtgatcca ccccgctcgg cctcccaaag tgctgggatt 256741 acatgcatga gccaccacgc ctggccgcgt ctcattcctt ttttcaatca aaggaaagga 256801 ggcttgcatt gaggaaggag tgcagtttaa gaggtaaagc cagctattcc ttgtcaaggt 256861 cttgaaattg ctagcattag cagctggtcc tctctgggtt tttaga'ggag tagataccca 256921 gaggccctgt gtggaaactg agttttatca gccagaggtt tgggcgtagt gctagtctca 256981 gagtcaaagg aagattggtc aaacttgagg aagagctact aggtggcagc aggctcttct 257041 tattcagaat agccacccca acccctgagg accccagatg catgacattc agtaaacttg 257101 ttgagttctt actatgcttt agaccttgat ccaggagcaa gatatatcaa tgggggaaaa 257161 aaaagattac tgttcctatg ggagaagggg tttggaggac aattaatgat gcctttctga 257221 tcttgaatct tcccactcat actcctccaa aagtcataaa tccaacaagg agaacaaata 257281 aaaacagaca actcatacct tcaagagcat taagagacag caacaagcct gtgatagcaa 257341 agagtgacac aggggaagct gatagaggct taagaagctg tgaaaaacag tacaggggtg 257401 tggaggactt aatcaaatca caagcaaaat tattccagaa agacaaaact gggatgctgt 257461 gtagttcatt cacagcactg gatgcaataa aggaggctga aagtgactgg aattggcagc 257521 tgttggaaag cattgcctct aggggagagt caaacggtgg tacctgttaa gacaggatag 257581 tgaaagtaaa gaaggaagga aaagggagaa attaaggatc ctgtggaaat gaaaaagaaa 257641 caagacaacc caaacccttc ttctttcgtc tcccagtgcc agctgtaaaa agtacataga 257701 agagggcaaa ggtgacagaa aaaaagactc tcagattagg aaccagttcg ttcattaaat 257761 aaataggaat agaataaagt agcccacatc tacccaaaac gactctcaaa cattgaaaat 257821 agggattagt gcattttggt tgcaaaaact cttgcaataa gtcaactgta aaattaaaac 257881 tgtgcataac actgaaatat gaattgaata tttgaattca tgctttttgg tgtatgaaac 257941 aaacaagcct acctttagtt agaagtacaa aagctaagta gagaaatgga caaaaaataa 258001 aatgaaataa aattagagtt aattgaactt ctggcaagaa tagaagaaaa gaaaaaatca 258061 aatcagaagt gaagactaaa ttgcaaggta cctaaaggaa aatcagatta aaatggcagg 258121 tggtaaccca acatattaat atttacattg aatgtaaatg gtctaaacat caaaatgaaa 258181 agtcagagat tggcaaaatg cattaaaaat atgaccaaac catatactgt ctacaagaaa 258241 cttcaactgt gtgatatcag taggactgaa aagaaaagga tgggtaaatg ctaatcaaga 258301 gaatggtgga tgcctataca aaggggactt cagaacaaag aaatttacta ggagtaaaga 258361 ggacattact tattgataaa acggtcaatt ctcaaagaag acataccaat cctaaacatg 258421 tattcagtaa acaactttta taatacaaaa agcaaaaaca agcagaactc aaatgagtaa 258481 ttgacagatc caccattaca gttgaggatg ccaatatgcc tctctcagta gttcatagaa 258541 ccactattca gaaaattagt aaggatatat taatagaaga actcaatgat actattaaat 258601 aataggatca aattgacatt tatagaactc cccacccaac atcagcagaa ttcaggttcc 258661 atacctatgg aatgtatacc aagataaacc atattctgga taataaacta tacaaattta 258721 aagaattgga atcataccaa gtattttccc tgatcataat gaaacctaac tagagattaa 258781 taacagatga caggtaaaat aactgaaaga agttttatct gaatgaaaac cttgtttttc 258841 tggccaggca ctgtgttata cacctgtaat cccagcttgt caggaggctg aagaacgagg 258901 atcacttgaa cccaggagtt tgagaccagc ctgggcagca tagtgagacc ccatctcaaa 258961 aaaagtcttg tttttctacc cttcattttg aattgttatt gacttggaac atgtgaaaat 259021 agatatctct catctgacag tgtgccaaaa ttataatggt atatattagt tgattgttat 259081 ccacgataaa ttgtttctct gtccattttg ttttacagct tctcttttaa aaggactaaa 259141 acatgctaac atagtgctac ttcatgacat catccatacc aaggagacgc tgacacttgt 259201 gtttgaatat gtggtaagta aaataagact tttaaattta gacatttaaa atatgaatga 259261 aattcttMta gtgttgtcat agaatttcgt ttttagattg ctgtactgaa gttaatattt 259321 tatctgaata catgagaatt ataattttgt ataaaataaa ggccctataa gagattattg 259381 aatgatatgt atcttaaaag aaaaacccag aaaaatgtta acttgaattt ttatcagata 259441 tgttatctat ttataaccta tttgttacta ggatacattg taatttttag gtttattaca

[0308] Following is a PFTKl genomic nucleotide sequence that includes the PFTKl SNP "PFTKl-AA" (SEQ ID NO: ).

ACTGAAATTGGCATGCTTTCTAGAGTTATATATTGGCATGTTTAGTGATATTAAAGTTGCAGTGAAGAGTTCTGAATTTAA TTTCTTCTTTTCTCAGATATGTGTCACAAAGATGTCTACACGGAACTGCCAGGGAATGGACTCAGTGATCAAACCCCTGGA CACAATTCCTGAGGATAAAAAAGTCAGAGTTCAGAGGACACAGAGCACTTTTGACCCATTTGAGAAACCAGCTAATCAAGT AAAGAGGGTGCATTCTGAGAACAATGCTTGCATTAACTTTAAGACCTCCTCCACTGGCAAAGAGTCACCTAAAGTTAGGCG GCACTCCAGCCCCAGCTCGGTAAGTGCAGTCTTTTTGTTTATCACTGGGTAAACAGAAGGAATAGCC[T/C]TCTTATGAT AGCATGCGGTGCTGGAAGACAGCAGGAAACTTTATCAGTGCCTTATTATGCATTCTCTCCCAGGGTGGTTGAATGTTTTGG AAGAGA

[0309] Following is a PFTKl genomic nucleotide sequence that includes the PFTKl SNP ^;'PFTK1-AB" (SEQ ID NO: ). TTTTGTTTTACAGCTTCTCTTTTAAAAGGACTAAAACATGCTAACATAGTGCTACTTCATGACATCATCCATACCAAGGAG ACGCTGACACTTGTGTTTGAATATGTGGTAAGTAAAATAAGACTTTTAAATTTAGACATTTAAAATATGAATGAAATTCTT [A/C1TAGTGTTGTCATAGAATTTCGTTTTTAGATTGCTGT

[0310] Following is a SERPINA5 genomic nucleotide sequence (SEQ ID NO: 4).

SERPINA5 REGION GENOMIC. >14: 92996751-93093150

1 gcaatgttgg gggtgttggg tttcacaact tgtgttgggg gtgttcaaac tgcaccagtt

61 tgtaagccct cccgccattt cgcagagctt ggtcaaaatg aaacattcca cgggattcga

121 gccgtgagaa acaccctgtc taaacacctc accacaaggc acaggaacgt ccttatcaca

181 ccctgctggg caaaggcccc actgaaggaa catcccYgcc ataccctgcc gggcaagggt

241 ccgaggaaca tcctatcaca ttctgtgggt aaaagggcca aactatctca tcgtgggaac

301 atgttatcaa cattttccca ggtggcaggc ctggccccac ccctagactc ctcccaccca

361 ggcctacaat tgtcccagcc tgtaagcaga gacaggcact gccattaagc tggtcctcca

421 cctctgcagg ttttatgctg gacataaatg ccagcagttg ctatagagct tctctctctc

481 tctctctctc tctctctctc tctctctctg tccctgtgtg tgtctttcct caactctcac

541 tttcccctta aaaaacctaa cagcRgagtg ctaataacat ctagccggta gaggccaggg

601 atactgctaa acgcgctacc aggcacagga cagtctcctc catccttaac atagaatcat

661 tcagcccaga gtgtcagcag caccaggctg agaagcccca ctctaagcta agtgctgagc

721 ttcccagaga gctcctagcc tcttgagggc agtccctcgg tcttgatgca cttacataca

781 cttgaacaca caccgaagga acagaaatgc cccacacctt aggagaaatg attctggaac

841 agtttgtagt cacaggatca gatgagagtg aagattataa gcctgccaga agggagctca

901 gctgcccttc ttgtgaaata ggcaatctga cagaggcttg catttccttc atgatttctg

961 tagacgcagc cctgtgctga gtgcaaaaga cagttggtca ctcaggccag agttgttgag

1021 agtcacacag agtcttgaat ttgaggttag aaagaccaca ttggcttcca caactctcag

1081 tttcctcatc tataaaatgg gcttaatact agttgcccta agcttatagg gatgttggac

1141 tgattcagcc gagcaatttt atgtttgcac gtggaaagtg ctcagtagat atccactatc

1201 ggcattgcct gtgccctgtg tttgtcttgc aggaagccct tctcctttat cacctcactt

1261 gattatcact acgttgctat aaagtggagg ttctggggct ggcatcctgt gattctcatc

1321 gtatgtgact ggcaaggaat aaagaaagac actcaggatg ctacagatac agaagctgac

1381 tgcacaggga cctgagaaag gaagggactg gaaggggctc agcaggagca ccaccagctc

1441 acacgcagag ccagaactgc cctggaagaa ttgggccagc tgctgccgaa tccatggagg

1501 gaactcagga catacaggag ggttcccctt ggtggggttg agggcatggc aaggacccaa

1561 tgatgcagtc agtgaaagga gacctggtga acggcagagt agcagctccc ggaaaagaag

1621 gaaggtaccc tgggaccatg ggcactgact tttgccgtct ttcaaccaca gtgctttggg

1681 cgacaactgt cggagataaa gcacccacgg gccctacatt tgggcaaaac ttgaagattc

1741 acaacgcttt tttaggttac ttcttccagc aaaacctcag agcaaccctc tgtggtagga

1801 agggtggttc ccattttcca gatgtgaaaa ctgcatccca gctggagaaa tcatttgccc

1861 ctgggcatgc aaacagcagt ggcagggcct gacttaacgg gagttctgtc caactgcaag

1921 ttttgcacag tacagctgcc tggagccaga gggtgcatgg gaggagagac agaggtgtcc

1981 tccccaaggc ctggaattga tcctgtactg gtaaataggc agagagcgtg tgccatgact

2041 cactgagaca agcatttcca accggaagga agaagcagag ttttgactgc agcctaggaa

2101 tcaggggctg acgtgtcacc ctctcccagt ggcctctgca ttgagagcac cggcgtggtg

2161 gtgcgacacg gagggaagca cttcttgcca caagcttctg gggacgtgga cagggaaacc

2221 cccaaatcag attaaacacc agagcctgcg aaagtcctgc ttcctcccca tgtctgctct

2281 tccaccaaca gaggatgtga ggaccccagg ttcaggggtg tctgctgaga gccctgaagg

2341 tcagggacta ccaagagaga aagagcatta gcttccagaa agtgcttcct gaagaaggtg

2401 gcctgcacat ggccctgtcc ccccgtggag gacctccagc ccgtctacaa ggacaggact

2461 catgtctaag aagactcccg tgtgatggtg tgatgccacc tgcagaacgt gttgccttga

2521 atgccagggg caccccaagc ctctatctgc catcactgcc tgtgcctctg tatctgtggg

2581 tgccggtgac cagctgtgtg cacctgggaa gctctccaaa cgtgacatga ccacgacacc

2641 agcaggcctt catcaaatgc ctcctacaga ggtctgactg ccacttcctg aggcccattc

2701 accagctggc ctcctgcggg aagaaaaccc agccatgtta gcacatgggg gccctgtttt

2761 tatgaagtca taagttacta tctcctatct cctcctctga gtgtgtgtgt tcacaggtgt

2821 catatagtac tctatgcaag catggctctc tgtgtaacat aagtcaccca tgtccataga

2881 aagagacaga gataactgca gatagaagtg tgtgcgggcc tgtcataacc agctacacat

2941 gggtgtgaac acctacagag acatggggtg gagacagaaa agcagagctg tgcaggtcaa

3001 aatcttaaat ccagggcatt cttggcaacc acagcattgg gcttctcttt gccacgtcta

3061 ccactttgat tgctggtggt gaggttgatg agagacctga ggggtgtcct ggcatccctg

3121 agacatgcac tcagctcccc gatggcacag ctggactggc ctgctctcgg ctgctccaga

3181 aatccccaaa ccctgtgggc atcccgtcac cgtggagacc gagtcaaaca tccctgggcc

3241 ccgtcctggc ctgctgagtc agctccYgca gggtggggtc tgcaatctac gggtaatcct

3301 ggcagggcca ggtggggctg tctgggtgat cctgaatggt gaggctagcc tggcatggat

3361 tggaaggagc cctcgcttct catttaatgg cagagctgcc aagaataagt cccaggtccc 3421 cggctctgcc cttcccaggc atgtccagcc ctgaagcagg agaaggtggg tgtgtggcca

3481 gcaggaggca cagacattct gaagtcagaa ttttccttcc aagttagggg ctgggacacg

3541 aagaaccagt atccctttct catcataaca gcaagaacga cgcttttgac cttggtctct

3601 tggaaacttg gaggcaaata gctgcatgac gccttcgagc tgtaaacatg cactctctac

3661 acactgagtc cacacagcct cctggctgcc acattctgtt ctgattcctt gaccgtgcct

3721 ttgtagtcag tcctgcagtc aggtagggta agtcctctac ttttgttctc ttttttataa

3781 ttgctttgat cagcattctg ttttgattta tatctctcct gattgtttag gtgtgccttt

3841 ttaatttcaa tttttttttg agatggagtg cagtggcacg atctcagctc actgcaactt

3901 ccgcctcctg ggttcaagca attctcctgc ctcagccttc caggtagctg ggattacagg

3961 tgtgtgccac cacgtccggc taattattgt atttttttaa gtagagacag agttttgcca

4021 tgttggctag gctggtctcg aacttctgac ctcaggtgac ccacctgcct cggcctccca

4081 aagtgctggg attacaggca tgagccacca tgcccggctt aattttaaat ttttttaatt

4141 taaattgggg aggtcttcaa agctgcctca aatcctttat gggatcaagt gtgacataaa

4201 cattttcatc cctctaagaa tgcagagctg gaaaagtcct tgaagatctt taagccgaac

4261 gtacacaaac ctgtactgtt tggtatgtac aaatgtctct aacttactga aattagaggc

4321 ccacagttaa aaattgggat agtttacaat ttaaaatgtc caaatttcca acttctttgg

4381 agtaatcagg agatctgttg atatggtcgt tagactggac acacagtttc atctatacct

4441 ccaacaagga ttcaaggagc atctgcacca tgtggacaca gccccaggca cggatgatat

4501 acatggcagt ggcacggtca gggatccccg tcctcctgga gccgacagca ggctctcctc

4561 tgagctcccg tgacctgtct ccttgtcatg ttaatgacct agccccagat ggtccagttt

4621 ataacccttt cctggtccag ccaccttgat ttacagatga ggaaactgag gcccagagag

4681 agaatgtgac ttgctgaaga ccacttagtg accaatggca gacgtagaac tagaacccag

4741 gcctcctgac tccagttccc aggacattcg tctgagctgg gctggctggc ttcaggcagc

4801 tactcccctg cccccatgat ccggttcagc tttccctcca ggtccctcca tcagggaccg

4861 cccctaggga ggggctccct cagtgctgcc aggaccccgg tgttttagta aatatgtgtc

4921 ctgtgctggg ctgatctgac ccctgtgggg aggggcccct ctccagcctc cagctgaggg

4981 caggcaatga cttccaccag gaatacacgt cattggcagg tccatcccct tcccgctgtc

5041 cagccagcct ggcgtctgac taatcagagc ccacaagccc accatgtgag tagccttgct

5101 gttccttagg ttgtttgcct ttggtttttt aatttttttt taacttacta tgatcaagct

5161 ctcagcaggc tcatccaacc cagtcatccc tgcagtgaaa cccgtcattt cagctgtgcg

5221 tgatgctcag ctagttgtct ccgaagcctt tcgtcttccc acccacacac cttttggagg

5281 ttggcaactg cccagttctc ctccccctgc atccaccccc tcaccgtctc cgtccttgca

5341 gtttctatgg tgctgctgag ccagggacca tcactttctt tgcaagatgg tttccatggc

5401 aacgggtgct gtggcatccg agtgaagcag aggctacctc ttctccagag acttcctggt

5461 gtggcctagg tgccctggct gcctccttcc gctcttgact tcttgtgtgg cctgggcaac

5521 ttgtgctctt ccctcagccg gaaatgctca gccatacttg ttcatatagt ttgtcctctc

5581 cctcgatgca gcacttggtt cagatgccac ttcctcaaag tggacatcac tgaccttttg

5641 cccctaatta ctctttatcc cctgctcccc gctgaacttc ttctggcact tagtacacgc

5701 tgaaattcta ttatttgttt atttgtttac tgcccaccac tctgtctaga atatacattc

5761 cacaagggta gaaactttgt cctgctcaat gcccagtttc cagaaccttg cacagtgact

5821 gccacatagt aggtactcaa tgaataacca atgattaagt aactggcccc atgtctcctt

5881 tccagatctc agccttctag tccatggaac atcatttatc caggtgtgat gttgggctat

5941 gtcgtgtcta cgagctatgc gttggagttc ttcaaaaaga aaaaggaaaa ggaacaatga

6001 cttgaaaagc cttttaaatc tgggactgtt tggagaatcc gttgcaatgt aacagatgac

6061 cccaaacctc agcggctgaa aacaacaatg gctttatttg cttaagattc ggtgggtcag

6121 gaattcagga cttagccaag tggttctttg gctccatgtg gtgccagcca gagtcattca

6181 ctcagctgca ttcagaccat gactcgctgg gctggtctgg aaggccacag aggctttgct

6241 cacatgtctg gtgcctgatt gttcctccat gagtcctctt tctctctctc tatttggtta

6301 gcttgggctt cctcatagca tggcagtccc agatcactca gacttcatat atggcagctg

6361 gcttctcaaa aggagcattc cagcatgtaa aagcagaagc tgcagaacct aaggcttagc

6421 ctcacgttgc atcacttctg tcccatgtta ttaagacaag ccacaactga tgtctaaact

6481 cagaggaagg ggaaatagac tccacctttt atgggaagag cagcaaaggc cttgaagcca

6541 tatttcatct accataggga caaatccctt accagatccc accaaaaaac ttggataaat

6601 atatactcca taggatcagg cctcactcag tgccactaat tggaggatta taattgtcca

6661 caaaaaggct aagcataatg acggactaag ataaaggatg agtttgctgc ggaaagtaat

6721 actaaggaca aaattgaggg agagtgtcag cccaacttgt gaaatatggc taatacctgt

6781 gctagttata cttcttttgg ttacaaaaac ataatcttag agaccctttg gattgcttaa

6841 acaaataaac aaacaaaata ttggaaggac taccaggttg tgggcgagtc tcacggagca

6901 tggaacaact ggatcacaga gaaaccagct ctggggactc agccgcaggg ggctacgggt

6961 tgtcttttga ggctctgctg caaccgcaac tcagcattca agactcttgc tcactgtttt

7021 cctcacttcc aaatctcact ttccaggaca gggactcagt ggcccatcat tcaggtgtgc

7081 tgctagctcc agcctggggg actgatatgg tctggctgtg tccctaccca aatctcatct

7141 tgaattgtag tgcccataat ccacacgtgt catgggaggg acccggtggg aggtaactga

7201 atcatggggg tgggtttttc ctgtgctgtt ctcgtgatag tgagtaagtc tcagggagat

7261 ctgatggttt tataaagagc acttcctctg cacatgctct cttgtctgct gtcgtgtaag

7321 acgtgacttt gctcttcctt caccttctgc catgatggtg aggcctcccc agccatgtga 7381 aagtgtgagt ccattaaacc tctttccttt ataaattacc cagtctcagg tatgtctttg

7441 ttagcagcat gagaatggac taatacatgg aaagacgccc aggcccggcc atggccttag

7501 ggactgtgca aggtatcagg ggcagatcct gaagagggga ggtgattgca acccaggggc

7561 aggatggaca cctcccactc aaatttgatc tggatgttga gaccaacaac aacacacRtg

7621 cacccgagga tatagcaaga tctaatgctc acactatgag gcttctcagg atagcagggc

7681 aggttgccta aggtgctctg aacatggctt gagaaatcaa ggaaagaaga ctgactgtct

7741 tggtgtttta tggtggttag tgggtggggc tggggtgaga attcccaagc acagtttgag

7801 aggcactggg ctatcccatc agtgggccca gatgtggggt agaaagggga gagggaggaa

7861 ccaagcctaa aagctgtcag cagccaagca tcaagaaacg gagtcagact gcattccaag

7921 gacctgctgc caagtccttc atagccacac agcagtttag agaacctgct cctcccttta 7981 ccctacaatc cacaacagct ccaaagcact gagacctagg agaccctgag ctgagggcta 8041 gagaaggaca gggcagaagg tcaggtgttt gctctgaacc tggacttcgg tcagcactgc 8101 acagagacgg cagcgtaggc aggaagcctg gggtgggaag ggcggcaagg ctgggctgga 8161 gccatggtgg gcagagggac agggtttgga ggatgaagca ggMcctcgaa gaacagaaat 8221 ccccatcccc tccctctctc ctcagttcag aaatatcttc accttctgaa atcatcagct 8281 cagcatcagt tagaaaatcc tcatggctat ggtgataccc gctctgcatg gccagaatca 8341 atgtcctcaa atcaaaccaa accgggatca acccaacgcc cccttctcca tgacgcttgc 8401 ccctatctcc ccttccctcc ccttgctctg cggcctgtgg cctcacctag ggctgcctca 8461 tcatgtcttt gctgctctct aaggtcaagg ttgctcacgt ctgtgccctg gatgtaccct 8521 ggcccccggg cacagccatc atcattccat gctccatact tctacaggac atttgcctat 8581 gctgttcccc tacctggaac actgttccac gcttggtacc tccttgtcat tctgctcagc

8641 tcaaatgctc cttccccagg aaacccttcc tgaaggcccc ctcccccagc cagcgaatcc 8701 ccattgcagt caatcccagc tcctgctcta cgcttcagag cccacccaca ctgtgtagct 8761 gcaggagctg ctcccgccaa ccaaaatagg gtgattttgc tcactgcagc aggagttcag 8821 taagtagctg agaacgagtg catgaagcaa tgaaggaatg aactcagggt gctgctgaag 8881 tcttctcccc actgggccag cggctgtttc tctttctcct ccaaccttcg acaagtctga 8941 gctcaggaga ggaaggggcc cgtgtgatgt gaacccagct gctgcgaatc tttctgagcc 9001 cagctcctcc attaacttgc cttagtcaag ttctaaccct cacgtaagag ggggtgtttg 9061 gctagatgag ctagcattaa cactttcaga atagtagagg actaagcctg tgtttccaaa 9121 cgcaaaagcc accttttccc accccaagcc ccagggcacg ggttttagga gcgcctgaag 9181 gcagtggatg tgccagtgca gttaagaaat ggaggcgcgc cctctggtgg tgaaaattca 9241 aactgcagag accaggcccc gccaaacgct tgccctgagg ccgtgggtga ttcttaagac 9301 ccgctagggg acagcattaa agtgcaggac ccccagaccc gccctgcacg cccacacccg 9361 tgattctgat tcaagagact tgggggaaag cctgtgattc tttgctttta ataactactt 9421 ctaggccagg cacagtggct cctaggattt tgggaggcca aagtgggtgg atgacttgag 9481 cccaggagtt ccagaccagc ctgggtgata cggtgaaaca cccgtctcta caaaaaatac 9541 aaaaattagc cgggagtggt ggtgcatgcc tgtagtccca gttactctgg aggctgtggt 9601 gggaggaaca tctgagccca ggaggttgag gctgcagtga gccaagatcg tgtcactgac 9661 ttccagtctg ggtgacagag caagactctg tctcaaaaat aaattaatta acgagtacct 9721 ctcttatgga ggactccagg gccacatttt gaggaatgtt ggtcttaggc aaaaagcagc 9781 tgaattcctt ggtatcctag tgcctcggtg gtgttatggg gcggtggcct ctgtgactgt 9841 gggtgtggcc tcagggtagc agaatttcgc tgggagacgc acagcttcct gcagggtcgc 9901 aggcccacag ggggctcagt ctacccacat aacccaagaa gaaagcctaa tcctctttga 9961 ggggaaagtg tgggttggga ctgcccccgg ctggctgcac aattggttga ggttaaatct 10021 cctttctaat agtactagtc aaaggcggag gtgaagagct tggactttgg Raccagaaat 10081 ttctgagttc aaatctcagt tttcccatat aggagctgtg cgacctcaag gaagatattt 10141 agcgcccctg ggcctccatc acctcctctc tttaatgaag gtaaagcatg tctcttagga 10201 ttcctaggat tatttaatgt cattacacta tcaaagacaa gacccagcac attgcaaaat 10261 ctccacagat aggatctggt tttgttgtag ttattattgt agttattttt attacttttt 10321 tccRtaggtt tttggggtac aggtggtatt tggttacacg agtaagttct tcagtggtga 10381 tttgtgagct tttggtacac acatcacctg aacagtatac actgcaccat atttgtagtc 10441 ttttatccct cgcccccctc ccacctttcc ctcaagttcc caaagtccac tgtatcattc 10501 ttatgccttt atatccccat aacttagctc ccacctatca gtgaaaacat tcgatgtttg 10561 gttttccatt cctgaattac ctcacttaga ataatagtgY ccagtctcat ccaggtcgct 10621 gcaaatgccg ttaattcatt cctttttatg gctgagtact attccattgt gtatacatac 10681 tgcagtttct ttatccactc attgattgat Kggcatttgg gttggttcca tgattttgca 10741 attgcaaatt gtgctactat aaacatgctt gtgcaagtat atttttcgta taatgactta 10801 ttttcctctg ggtagatacc cagtagaggg attgctggat caaatggtag ttctactttt 10861 agttctttaa ggaatttcca cactgttttc catagtggct atactcattt acattcccac 10921 cagctgtgta gaagtgttcc ctgttcaccg catccatgcc aacatctact gttttttgat 10981 tttatgatta tggccattct tgcaggagta gggtggtaac acattgtggt tttgatttgc 11041 atttccctga tcattagtga cattgaggat tttttcatat gtttgttggc catttgtata 11101 tcttcttttg agaattgtct attcatatcc ttagcccact ttttgatggg attgtttgtt 11161 ttgttctcag atttgtttga gttcactgta gattctggat attagttctc tgtcagattt 11221 atagattgtg aaaattttct cccactctgt gggctgtctg tttactctgc tgacagttcc 11281 ttttgccgtg caaaagctct ttagtttaat taggtcccaa ctatttatct ttgtttttat 11341 tgcatttgct tttgggttct tggtcatgaa attcttgcct aagccaatgt ctagaagggt

11401 tttttcaatg ttatcttcta ggatttgtat agttttaggt cttagattca agtccttaat

11461 ccatcttgag ttgatttttg tattaaggtg agagacgagg atccagtttc attcttctac

11521 atgtggctaa ctaattatcc cagcaccatt tgttgaaaag ggtgtctttc cccaacttta

11581 tgtttttgtt tgctttgtca aagatcggtt ggctgtaagt atttgggttt atttcgaggc

11641 tctctattct gttccatcgg tctatgtgcc tatttttaaa ccagtaccat gctgttttgg

11701 tgactatggt ctcacagaat agtttgaaat caggtagtgt gatgccccca gattcctact

11761 ttttgtttag tcttgctttg gctatgcagg cacttttttt ggttccatat gaattttaga

11821 agtgtttttc ctaattctgt gaaaaatgat gggggtattt tgatggagat tgcattgaat

11881 ttgtagaatg cttttggtag tatggtcatt ttcacaatat tgatactacc catccataag

11941 catgagatgt gttcccattt gtttttgtca actatgattt ctttcaggag tgttttgtag

12001 ttttcctagt agaggtcttt tgcctccttg gttaggtaca ttccaaagta ttttaccttt

12061 tttgtagcta ttataagagg agttgagttc ttatttgatt ctctgcttgg ccgctcttgg

12121 tgtatagaag agcaactgat ttgtgtacat taatcttgta tctggaaact ttgttaaatt

12181 cttttatccg ttataggagc tttctggagg agtttttagg gttttcaagg taaacgatca

12241 tatcgtcagc agtgagagtt tgacttccat tttaccaatt tggatgccct ttatttcttt

12301 ctcttgtctg attactttgg ctaggacttc caggactatg ttgaagagga gtggtaagag

12361 tgggcctcct tgtcttgttc cagttctcag agggaatgct ttcaactttt ccccattcag

12421 tattatgttg gctgtgggtt tgtcatagat gacttttatt acattgaggt atgtcccttg

12481 tatgccgatt ttgctgagag ttttaatcat aaatagatgc tggatttttt cgaatgcttt

12541 ttctacagct attgagataa tcatgtgatt tttgttttta attctgttta tgtggtgtat

12601 cacatttatt gacttgtgta tgttaaacca tccctgcatc tctggtatga aacccacttg

12661 atcatggtgg attatctttt tgatatgttg ttggatttgg ttagctagta ttttgctaaa

12721 gattttagag tctatgttca tcagggatat tggtctgtag ttttcttttt tggttatgtc

12781 ctttcctggt tttggtatta gggtgatact ggcttcatag aatgaaagag agggttgcct

12841 ctctctctgt cttgtggaat agtgtcgaaa agattggtac caattcttct ttgaatgtgg

12901 tagaattctg ctgtgaatcc atctggtcct gggctttttt tgttggttat tttttattta

12961 ctatttcaat cttactgctt attattggtc tgttcagagt atctaattcc tcctgattta

13021 agctaagatg gttgtatttt tccaggaagt tatccatctc ttctaggttt tctagttgat

13081 gtgcatagaa gtgttcatag tagcctcaaa taatcttttg tatttcagtg gtgtcagttg

13141 taatatgttc tgtttcattt tttaatgagg ttatttggat tttctctctt ttttcttggt

13201 taatcttgct aatggtctgt caattttatt tatcttttca aagaaccagc ttttgtttca

13261 tgtattttct gtgttttttt gtttgtttgt ttcaatttca tttagttctg ctttgatctt

13321 gattatttct tttcttctgc ttggtttggg tttggtttat tcttgtttct ctacttcctt

13381 gagatttgac cttggaatgt cagtttgcgc tctttcagtc tttttgatgt agacatttag

13441 ggctatgaac tttcctctta gcacagcctt cgctttatcc cagaggtttt gataggttgt

13501 gtcattattg tcattcagtt tgaagaattt tttaatttca gtcttgattt catttttgac

13561 ccaatgctca tctgggagca ggttacttaa tgtctgtata tttgcgtggc ttcaaagctt

13621 ccttttggag ttgacttcca gtttcattcc actgtgatct cagagagtac ttgatataat

13681 ttcaattttc ttaaatttat tgaggctcat tttatggcct atcatgtggt ctatcttgga

13741 gaaaattcca tgcactgttg aatagagggt ggattctgca gttgttggat gaaatgttct

13801 gtatatatct gttaagtcca tttattccaa ggtatagttt aaatccattg ttcttttgtt

13861 gactttctgt cttgatgacc tgtctagtac tgtcagagga gtattaaagt cccccactat

13921 tattgtgttg ctgtctatct catttcttag atatattagt aattgtttta caaatttggg

13981 agctccagtg ttaggtagat atatgtttag gattgtgata ttttcttgtt aaacaaggcc

14041 ttttaccatt gtataatgtc tctctttgtc tcttttaact gctgttgctt taaagtttgc

14101 tttgtctgat ataagaatag gtaaccctgc ccacttttgg tgtccatttg cattaaaggt

14161 ctttttccac ccctttaagt ttatgtgagt ccttacatgt taggtgagtc tcttgaaggc

14221 agaagattgt tggttgctga gttcttatgc attctgcagc tctatatctt ttaagtgggg

14281 tatttaggcc atttacattt aatgttagta ttgagatgtg gggtaccatt gcattcattg

14341 tgctatttgt tgcctgtgta ctttggtttt tttgtttttg tttttgcttt ttaaaatgta

14401 tttttgtatc acaggtcctg tgtgatctat gttttaaata ggttctgttt tgatgtgttt

14461 tcagaatttg tttcaagatt tagagctcct tttagcagtt cttatagtgc tgccttggta

14521 gtggtgaatt ctctcagcat ttgtttatct gaaaaagact gtatctttcc ttcatatatg

14581 atgcttaata tcactagata taaaattctt ggctgaaaat tgttttgttt gagaaggctg

14641 aagatagggc cccaatccct tctggctggt agatttctct gctgagaaat ctgctgttaa

14701 tctaataagt ttgcctgtat aggttacctg gtggttttgt gtcacagctc ttaaaattct

14761 tttctttgtc ttaactttag ataacctgat gacaatgtgc ctaagtcatt atctttttgc

14821 aatgaatttc ccaggtgttc tttgtgcttc ttgtatttgg atgtctaggt ctctagcaag

14881 actggggaag atttccttga ttattcccgc aagtttggaa atgttacctg gtgctttcca

14941 aactttcaga tttctcttct tcctcgggag caccgattat ccttaggttt ggtcgtttaa

15001 cataatccca aacttcttgg aggctttgtt catattttct ttgtttttgt tggattgggt

15061 taatttgaag atcttgtctt caaactctaa atttctttct tctacttgtt caattctatt

15121 gtaagacttt ccagagcatt ttgtatttct gtcagtattt ctatcagtgt gttcaatgtt

15181 tcctgaagtt ttgatttttt taatgctatc tatttccttg aatatttctc ccttcacttc

15241 ttgtattgtt ttttggattt ccttgcattg ggcttcacct ttctctggtg cctccctgat 15301 tagcttaata actaacctcc tgaattcttt ttcagataaa tcagggattt cttcttggtt 15361 tggatccatt attggtgagc tagtgtgatt ttggtggtgg ggggtggggg gcgggggggt 15421 ggtgttaaag agccttgttt tgtcatatta ccagcgttgg ttttccggtt ccttctcatt 15481 tgggtaggct ctctctgagg gaaggtctag ggctaaaggc tgttgttcag attcttttgt 15541 cccacactgt gttcccttga tgtagtactc tccccctttt cctatggatg tggcttcctg 15601 tgagccacgt tgcagtgatt gttatttttc ttctgagtct agccacccag caagtctgcc 15661 cggctccagg ctggtacggg ggtttgtctg cacagagtcR ggtgatgtga accctctgtg 15721 ggtctctcag ccatggatac cagcacccgt tttggtggag gcggcagggg actgaaatga 15781 actctgtgag ggtttttagc tttggtggtt taacgttcta tttttgtatt ggttggcctc 15841 ctgccgggag gtggcgcttc ccagagagca tcagctgtgg tagtatggaa aggaactggt 15901 ggtggtgggg tttcagaact cccaagagta tatgttatta gttttccgct atcagggtgg 15961 acagggaagg cccatcgagg ggcagggctg ggggtgtctg agctctgact ttctttgggt 16021 gggccttgct atggctgctg tgggggatgg gagtgaggtt cccatgtcaa tggagttatg 16081 tacctaggag gattatggct gcctctactg agtcatgcag gttgtcagga aagtagggga 16141 aagccagcag tcacaggcct cacccagctc ccaaacaatc tgaagggcca ttctcattcc 16201 caccatgccc ctgctaacag ccctgagtct gtttccaggc agtgggcgag caggtcttgg 16261 gaacttgccc caggttactc acctcccaac tgcgaaagaa tagggctttg gttcttcccc ^' 16321 tacctgtgga gtcggcacac tggattcgca cccttcccca agttctggcc agcaagcttc 16381 ttgccctgtt caaattgtta caaatttcag ctggagactt ccttctccct gtggcatttt 16441 gccccacacc tctggccacc ctcccaaagg gctcctgtgg tgccatgcag gaatggcctg 16501 cttgagatcc agcaagctcc cagggccttt ccccctgctt cctctacccc tgtatttcgc 16561 ttggctctct aaatcgactc agctccaggt aaggtcagaa acttctccca caaactacac 16621 cttcattttc cccagtgggg gtgtgtgttt catagcagaa ggtctccctt tcccatttcc 16681 gcagtttggg tactcacagt atttggggga tctcctgggt cctgcagaag cagtccactt 16741 ccttcagagg gtctgtgtgt cctctcagga ttcctggttt gttcttgaag tcattctgac 16801 actaaaattc accatgcaag cctccgcatg ctgctctgtc tatccaagtc agagctgcaa 16861 tctagtcttg cctcccatcc accaggatga tcctgaatga agtctaatta ttgtttttta 16921 ttcaactgac cctaacatag gacttgttct gtgctaagca atgtgctaag ctgtgaaagt 16981 tagagggaag gacacaaatt caggaagaaa aaggaataaa acactgtgct tgcttcctaa 17041 aaacccatag tccagcaggg acatcatatg tggtagtctg aaagcatatc cactttgaag 17101 atgactctag tctcagttcc tgtccaactg caacctcata agagaccctg agcaaaaacc 17161 acccagctga gcccagtcaa cccccagaac tgtagagata gcaataataa tgacaaacaa 17221 ctgccattgt tttatgccgc taaatttggg gtggcttgtt tcccagctat acataagtag 17281 gatgtatgtg tatcctgtgt aactatgtat ctaaaagcca gatagaaaat gatgagttta 17341 agagagggac agataattag acgtagagtt cctagagagg ctaaacagcc cacctacacc 17401 ttttagcatt tccaggcaag catcaagccc tgagcccctc taactccagg gatacatatt 17461 gtgttgcatg agtgttttgt tgaagctctg cactcttaag ataacatggg ggaagcactt 17521 ctctccttcc tctttgtaat tccttctcag tctccacctc tcaacacctt tcagtcctct 17581 ttcacatgag taaagcattt aagaatcagg agacctgttc ttgaccacct actctggaat 17641 ttttgcatgg agctctcttt ggactgtagc atctatagtc ttcctacctc catccaaacc 17701 aagactggaa gagctttgtt gttgctgttc tgtatgagca catacccatt tcttacaaga 17761 ctggaaggaa accaattata tctagtcata agctgaacac caggtttgca aatgatttta 17821 ttttcttctc caggtttttt ttactttccc atatttttca tgatgaccat tattgcattg 17881 ccaatcaaat tcaaaacaag gacagccttt ttaagggcag attaatttcc tggctccatt 17941 tggaatccag ggaatgggaa ggggattggg agcagttagc aggagggcag cataagtgga 18001 gcctgtgctg gaatgggaga ccaagacagc cattgagaaa gggctgggtt gcaatttagg 18061 atgcagtgga gcagaggagg gtgtcaggga gtgggattca tgcctacagc acagttcagg 18121 cagtttctgg gatgctggaa aaagcggctc cctgccgggg acatcagtgg tgtcacagca 18181 gctgccccat ctggcccagt ggtatttcct aggggcagag aggcagtcaa gccctctgct 18241 tccccacatc caccctggcc ttcctggtca ggcaacttat ccctgcttcc ttaaatcagt 18301 acttgccgag agtgttgcag attttaggag cttgccactg gaacatctga gcagcacctc 18361 tgagcagggc ctttggcatc tcttcattca ttcattcatt cattcattca ttcattcaat 18421 gactgacttc tgttaagcat cttctatagg ccaggcctgt tctaatgtgc ccagatatga 18481 ctgtggcaca attcattgtc ctctgggacc ttacagatga ttaacaagaa acacttggcc 18541 ttcaaattgt aacaggcaag ggttcaacaa tcctgaagcc ctcccagaga ccttaagaca 18601 agaagcaggc aggactgagg ctggagttag caactgagcc cagcctgcag ccacaccaat 18661 tgccgtcatt ccctccttct cctgcagggt ccaagtcagt agctcccact acatgcctga 18721 gagttctttc cacctttcct ttatatgggc ctgctctttg caggaaaaaa taactgctgt 18781 agcccacggg gactgcatgg acttcatggg attcaagaat ctccctaaat tgtaaaacat 18841 acatctgtgc atatttcagg gagagttcaa agctttcttg agataatcag gaccacaact 18901 caaaacaagt ttaacaacat ggtttcagcc atgtgtacac ctttggggat aaatgagtaa 18961 tgtacaaccc atctgaaata atacgacaga ctaactcacg cttccactgc actcactatg 19021 gccagatgct attctaggac tttacagatg tcagtttact gatcttgttg acaaccctga 19081 gatttagggg caattattac ccacagttta cagatgaaga cactgaggca gagttaagta 19141 acttaagtag tggtggagtc tagattcaac ccagacagtc tggctgtcca ccactgctgg 19201 gatgggaagg gaagaaggaa gcacccatta agactgatac agggctcaga acatttaaga 19261 gtgctgcccc cctgccctta atatcagttt tctgattagt gattattgct tctcatttga

19321 cacgtgaaaa actgaggttc agagaggtgg agtgacttgc ccaaagtcac aaatctcagc

19381 agtgagggag cttgtctgac gccaaagccc agcctctgtc cagaacatac caggggcagg

19441 cgccagaaac taaagggcag tgactgtgtg ctcatggcag ggacaagctg tccatcccct

19501 gggctgcagc caagcatacg ctaacccctg gaatctgtgg catcagcccc aaactcactg

19561 aagaagcaag actaaaaaag caaaacccca gactgtagac cattgtaagg ggaataatgt

19621 attttcacat tcatcagagc aaaaatccat ggccatcttt cactcattga cttactcagt

19681 caacatccat ggagcatgtc ccctgcacca cattctgctc tagcgcgtgg tacagcagta

19741 agcaaagcag cagctgctat tccggtggca ggaaaagtct gtccaagtgg agaagcagca

19801 gatgctggga aggaatatgg gcttcatgtt cagtggccac ggagcagacc ctgactctgg

19861 aatctgagct aacaatgtct ccgggcttac attttctcat gtgtWaaatg ggccaagctt

19921 agtataccta gagtgtatag gcaagggaaa gagagagatg agtgagggaa agcgagaatc

19981 cactgagaca gtagctctca ctttgcctga cctgctagct tcctctcttg tcctggtgtt

20041 gacccatttt ggacctcagg ccagctggct ccagggctgt gcttgtgcct gctctgccat

20101 ccccatgtct acatcgctca gggctcccag cccactgtgc tgctcagtgg tgtatatttc

20161 acttacctta aggcccaacg acttggaaac acatccagaa agtctgctag aggatgcctg

20221 aatggtcaag gtcatctcag tcagggcacc cagggccaca ttgctccctg cagtccttcc

20281 ccacatagct tgagaaatgg ctgccccagg agggtgcaag ggtgcaaggg tgcaggggtt

20341 cactgattac tggggagaga acaagttcaa ttccatggtt aaagaagaaa aatgcaaatt

20401 gaatacctgg cccaaggagg ttcctggtcc caccccatgc cacccttgcc ctgggatgta

20461 ctctccttat ggtctgacct atgagatctc agtggactct atcctcagaa atcacagagt

20521 ccaggattgc aaactggagg ccctgctgtg aggccctgcc cacaggtggg tcttgcctgg

20581 cctgtagaga gctggctctc tcacttccac acatccccac cattccccac cgtggcacca

20641 tggagtcttc cttacctgat ctaggaaggc ggcgctggag cttgctgccc cctgtctgat

20701 ccagcccctc atgttgtagg agggaggtgg gcgactgaag ctcagagagg gagtaaatga

20761 gctcaacttc acacagctag tgaggggctg gttggagacc agattttcca agtggttccc

20821 cgggccctcg gggagcagca agggccaggc gaacctccat gcactgYaca aacatgaaga

20881 agtgaaccct cttggggttc cccaggtggg aagtggggtg tcttcttggg agggggtgaa

20941 ccaacttctg gtgagttttc cttgttgaRg caatgctgca cccgtagcct gtttgttaat

21001 aattacctgg tcRggagaga gtgggtggta ctgagaaggc ctggtttgac cagtcctcct

21061 gggcttgata agacagagct gagacagcca cccagggggt ccactccagg acagactgtg

21121 ccgtgagtaa ccccYtgaga caatggagac gagagactct agagggaggg tgaccaactg

21181 ttccactttg cccaagactg ataattcttc tgggatatat tttcagtgct aaaaccagga

21241 aagtcccagg caagctggga cactttgtca ctcttgctag aggtgagaaa tactcaggct

21301 agaaaggccc Ygacttaggg tccatgggca ctggtgggtg actatgcccg gagacccaga

21361 aaagcctccc ccagggacac acagctggta cagggcggca ctgactgagg gccaaggtct

21421 tctggctgcc aatccaggtg atcttgggga gctcatgccg gaggggaggt gtgtctgtga

21481 gtgatgcggt cctatgtatg tttctaaatg atccctccaa ctgctgagtg gagaacagag

21541 agcagaaaga ctaggaagct ttctgcaagg gtctaggtca ggggtcaaca aaccacagct

21601 tgtaggtcaa atccggccca ccgcccatga gctaagaatg caagatgtaa aatataaata

21661 taaaatataa gtgataagta taaaagataa atatataaag ctatgaaaaa tcaatagaag

21721 aacaacattt tgtgacacag gaaaataata tgaaattcac atttcagtgt ccgtaagtga

21781 agtttcactg aaacacagcc acgcctcttc atgcatgtcc ggtctgtggc tgtttccagc

21841 tgccacagca gagttgggta gtggcagcag agactgtgtg gtctgcaaaa ccacagatat

21901 tactatctgg cgctttgcag aaaaagtttt ctgagccctg gttgaggatc atagcaaaag

21961 agggggcgag aggctgaaga acctacagga gagtctagga gttggagacc agcttgggca

22021 gcatggtgag accccRactc tataaaaaat tagctgggtg tggctgtgca tgcctgtagt

22081 tccagctact tggaagggtg catgcctgta gttccagcta cttggaaggg tgaagtggga

22141 ggatcacctg agctcaggaa gtcaaggctg cagtgagcca tgattacacc actgcactcc

22201 agcttgggtg acagagtgag accctgtctc aaacaaacaa acaaacaacc aaacaaacaa

22261 aaaaaaccca accctgcagg tcatggaagt ggattaaatg gattttgggt ggatagaagc

22321 ctagaagctt tttggcctga caaccggata ctggtgggac catttgatgg ggcaggagca

22381 gatttggggg agaaactgga gtatcctttc ttggacagat gttcattatg aaaYgggtac

22441 caattctatc cccRcaactt tgggcaggtc acttattaaa catccatgtc cttgtctgta

22501 cggggtaaca atacaaagac cagttctact gacctctaca ggggtgggag ggtcaaacta

22561 aatggctgaa agtggtttgt aaaccatata aagcactcca cagaKgtttg tggaacagac

22621 cctaaaataa actctgagga tWgccatcct ccatgcaaaa tcactgcact aatgaaatca

22681 actcatctga aagacaagtg tgggagaagc agcacctgag tctggggatg tgggttctgg

22741 ctgggatatg tgctaggtag gtgacttggg tgagtcactt tgggagtctt catttcctgc

22801 tctgttgggt gagaatggag tctagtgctg tgcagagctc acacaggtgg gaaacacaat

22861 gacatgatgg acacaaggag tgtgccttgt aagtctaaaa cattgccatc caatagtgtt

22921 gctgtcacca tacatgtgga aggtggtggg tgttacattg cctttcacaa gcccatctgc

22981 aggagttgag ggtgtcactc acgatctccg ggtgctggcc cactgccagc cttctcagta

23041 gggccaggtg ttcttctggg ggaatttcct gggcattctc ttccctccca taggcctgag

23101 agtgcagagg atgcatctta tcgactacct gctcctcctg ctKgttggac tactggccct

23161 ttctcatggc cagctgcacg ttgagcatga tggtgagagt tgcagtaaca gctcccacca 23221 gcagattctg gagacaggtg agggctcccc cagcctcaag atagcccctg ccaatgctga 23281 ctttgccttc cgcttctact acctgatcgc ttcggagacc ccggggaaga acatcttttt

23341 ctccccgctg agcatctcgg cggcctacgc catgctttcc ctgggggcct gctcacacag 23401 ccgcagccag atccttgagg gcctgggctt caacctcacc gagctgtctg agtccgatgt 23461 ccataggggc ttccagcacc tcctgcacac tctcaacctc cccggccatg ggctggaaac 23521 acgcgtgggc agtgctctgt tcctgagcca caacctRaag ttccttgcaa aattcctgaa 23581 tgacaccatg gccgtctatg aggctaaact cttccacacc aacttctacg acactgtggg 23641 cacaatccag cttatcaacg accacgtcaa gaaggaaact cgagggaaga ttgtggattt 23701 ggtcagtgag ctcaagaagg acgtcttgat ggtgctggtg aattacattt acttcaaagg 23761 tgagagtcag atcattggta tatgctaaat ccacaccacc gcctccaacc cactaatttg 23821 ttgactggtt aaatatattt ttacaaaaat gtaagtaaaa acgttgtgtc tgatagggtt 23881 gagcaaccct cagggaatgc aatgtgagaa tgttgtatgt tgaagactct gtagtattga 23941 ggtttccatt ccttcctatc tttagacata ttttcttcat aaaaataatg tataaaatgc 24001 attatagcca gtgatcatta gttgaattgc tggattcata tctgagctca gcctctacca 24061 acagtgcaaa caggtcagct tgtttgctca aagcagggat aagacaagtc tctaattcaa 24121 aggttggctt tgaggatcaa atgattaacc catgtatata ctccttagaa aagggtctaa 24181 agagatgggc aaactacagc ccatgggcca aatgtgttca gccactggtt ttgtaaataa 24241 agttttattg gcacacagcc aggcccattc atttatgtat tgtctgtggc tgacttcatg 24301 ctacaatggc aggttgattc attactgcag agattgaatg atctgcaatg cctaaaatag 24361 ttaatatctc tataaacctt ttggtttgtt gacccctgac cattttatgt actcaataaa 24421 tagcaactat aattcatcta atgataacaa tgctcatttt gaagctttaa aaatatgtaa 24481 aagcataaag gagaaagtag acataatctc tagtcctacc actcagaggc aacaaatgtt 24541 aatgttttag catcttttct tcaccttcca ttcacacaca tatatgtcca cacagttgat 24601 tttgcagtgt gcaaacaact ttgtacggtg tgtattagcc agggtttcat cagagaagga 24661 gagccacctc aagtcaatgg taaggagatc attataggaa ttaggcccca cacaattgcg 24721 actgggaaag tgaaggtcta gaggaaagaa gagttggaag gacagagaga aagttgccaa 24781 tgtaagcgga caagtcagag cttagagggg aatctatatg ccaggctcaa ccagccatca 24841 gagtgctgcc atggagggga gcatcactgc atagtttctg tggtagcctg gggctgctgt 24901 tgtttagtgg ggttagactt gggaaatgag cttggagaca agcagggcaa actggagcac 24961 acagagcact gctgagtctg accatcatca tatctgacta ccagggcctt cagagggcaa 25021 tctacttcga aatctcacag ttctaaccag cttgaaccca aaatctacag ggaacaaaat 25081 tctagggagc aactcccagc ctaatgattc agccaaatta gtcatcccat gtaatttgca 25141 tgtggaattt tcatgaacca ttgaaaagtt tttttaaaaa agctttgttt tgaggctggg 25201 catagtggct cacacctgta attccagcac tttgggaggc caaggcaggt ggatattgaa 25261 atcagaagtt caagaccagc ccggccaaca tggcaaaacc ctgtctctac taaaaataca 25321 aaaaaaaaaa aaaaaattag ccaggcttca tggcacatgc ctgtaatccc agccacttgg 25381 gaggctgagg caggagaatc gcttgaaccc aggaagtgga ggttgctgag attttgccac 25441 cacactctgg tctgggtgac agaatgagac tctatctcca aaaaaaagtt ttgctttgaa 25501 ataacaaaac ttttaaactt ta aaaaaaa attaactaag gaaggaagag aaacagtagt 25561 atgggtttca ctgtcaggaa gacattggtt agaatcccag atcccttgct attccctgga 25621 ctaaaattcc tggcatggag gccttagtcc attcacccta cctgccacca cctcactgca 25681 catcgcctcc tgtatttgct tccctcctca cactgcagcg attccatggc catcattgtg 25741 gtcacttcct tgcaaacact ctgaactctt aacttccttg gttttccctc cctctatcat 25801 acttaccctc caaagctgca aacctgctta aacctaaagg tctaactagt ctacatctgc 25861 acccagcagc tgaatgtggt tgaagaaaaa catccaacgg ggctgatggt ctcacttgat 25921 atttgtgaat gcaaattttc attgatatct ctacactgtc cagcaatcct acctacatat 25981 cYccactctc caaaacaact ataataacag attcgtcctt ctcaaatgtc ctccccactc 26041 atgactttca cttaacaatc ttgtctcact tttcattRag aaaacagaat cagttaaaca 26101 ggaaatctct catcttctca cctccaaatc tactcacctc caaatcttct cacctccaaa 26161 tctactcgcc tccctgcatt tgaacccaca agctcagatg ccctcctctc atcatggcag 26221 tagtgaccca cctcttatgg aaggctgacc cctctgctca cactctgcca tctcctctct 26281 ccttctcaag gatgctcacc taacaatgaa actctctttc cagcacccct tgtttcttct 26341 ctatcaatcc tactcacata ttagaaaacg aacatcctct gctatctctc attttaaaat 26401 ttaaatgagg cctaaaggat ccattcccca ggcatgtcag gttttgaatg gtcaaaatgg 26461 gacatcttga tgggctcata gggcaggatc tggagcgact gtttctgtag ctcagaacac 26521 cagatggcat tccctggctg gaggactagc tctgtggcct gcagaKgtcc tgtaccttct 26581 tttcatcttc ccttcagccc tgtgggagaa accattcatt tcctcaagga ccactcccaa 26641 agacttYtat gttgatgaga acacaacagt ccgggtgccc atgatgctgc aggaccagga 26701 gcatcactgg tatcttcatg acagatactt gccctgctcg gtgctacgga tggattacaa 26761 aggagacgca accgtgtttt tcattctccc taaccaaggc aaaatgaggg agattgaaga 26821 ggttctgact ccagagatgc taatgaggtg gaacaacttg ttgcggaaga ggtaatcagt 26881 gtgctWtggg ggctgaatct acagtactat ccatcaaatg taactttcta atgaaagaca 26941 gtgccccaaa atagagagtg aWcaccaaat tatgagagaa ttctcacttg ctctgagaac 27001 ttccatgggc ttcctttaaa tgatgaactc tcctgttata tttaaaatat gacttccccc 27061 tctttaggca aaaaagaacc acagtaggag ttcagagtcc tgggttctag acatagctct 27121 tccactgcac aagacttggg tcaagtgact cttcctctct ggggggttac ctctgtgcaa 27181 tgaagaggta gcccttctgg cccagaaggt tgactaagct gccatagtgg gactYaaaaa 27241 aactccatcc acctacccaa ggaattaata ggaaggcttc ccatcactct ggttatgatt 27301 ggaaaaagtc ttcaaccata tataagaaaa ggatcctagc ccaagggcac atgtggatag 27361 aaaattcaca caactttcat gatggagaga atccaatcca aagaaattag ctggttcaaa 27421 aagaataaaa cccacagggc tataacagag gcaaaggcaa aactgccacc tggcgaggct 27481 tacatctgtc tccctgggca cctgaacacc cacaggaagc aacctctgaa gaggggttcc 27541 caaggacggg agatcccaca gacagcaggg cctgggtaca aaggaacctg gcctttcaac 27601 atccatttgt gggaggtggt ctgagccgaa gc gtttgtg gggacagaac tcagatggaa 27661 tagagccagc tagagagggc caccaaggag ggctctgccc agcagggatc ctggcttgtt 27721 cattaatcta atgttctaac tcaRtgcccc tttcaggaat ttttacaaga agctagagtt 27781 gcatcttccc aagttctcca tttctggctc ctatgtatta gatcagattt tgcccaggct 27841 gggcttcacg gatctgttct ccaagtgggc tgacttatcc ggcatcacca aacagcaaaa 27901 actggaggca tccaaagtaa gtcgtcaaca gtcagcaatc cctagagaac tcggtagggc 27961 agtgcccatg ggagctgcca ggcgatgggg ctcccaagct gccacatgga gtctcagagc 28021 ctgagtgtgt tcagtcatct acaggcatca gcatccacca atcaaccagc cctggacgtg 28081 gtgctaggtg ctggagatat agtgttgaac cagcccctgc cctcagagag ctctcccagt 28141 ctagtcaggg acacagcgtc ttcatagaga gataaacgca atgatagaaa atggaggagg 28201 ggccgggcat ggtaactcat gcctgtaatc tcagcatttt gggaggccaa ggcaggcaga 28261 tcacttgagg tcaggagttt gagaccagct tggccaaaat ggtgaaactc caactctact 28321 aaaaatacaa aaattagaat ggtgtggtgg cgggtggtgg gcacctgtaa tcccagctat 28381 tcaggaggct gaggtaggag aattgcttga gcctgggagg cagaggttgc aatgtgacca 28441 gagatcaggc cactgcactc cagcctgggt gacaaagtga gtgagactcc atctcaaaaa 28501 aaaaaaaaaa gaaaaaatag aggaaacaga gaggagagac acaggtgagg ctgcattggg 28561 tgcgtctgta ttagggagac tttgcagata agagaaagag actcaagact tctgataaga 28621 aaagtgcacg agggggtaga gccttgggtt caagcttgaa ttccggttct tcctcttatg 28681 gttattgaaa gagtactagt ttctgaattt attttcctca cttttaaaat ggacatcata 28741 ctgctgacct cttaggatgg ccatgaagat caaataagat gcatgcaaag ccccgggcac 28801 agagcaagtg ctcatttaat gagagctacc atgattgtgt gtggcaggag gtctctagct 28861 caaaaatccg cccaaatgaa attcttgctg tgttatcccc aagaaatggc cttgcaggct 28921 gttatgtgca atattattcc ctagcaattt ctggctctcg cagtcttgtc caggccccct 28981 ctcttgctgg cttggagata atgcttgtga ttttcctccc agagtttcca caaggccacc 29041 ttggacgtgg atgaggctgg caccgaggct gcagcagcca ccagcttcgc gatcaaattc 29101 ttctctgccc agaccaatcg ccacatcctg cgattcaacc ggcccttcct tgtggtgatc 29161 ttttccacca gcacccagag tgtcctcttt ctgggcaagg tcgtcgaccc cacgaaacca 29221 tagccctccc agggctgctc atctgttcca agcaggagga tgtggcaggg gagggctggg 29281 agtgagtagc tctgtgttta gagttgggga caaggatgac accgaaggtc caggagtcca 29341 ggacagcagg tgctggccgg tggggagcgg ggaggggcac tgagatgggc agggcctgga 29401 cattccacac cctggtgctg tgcagcctct ggcagagcat ccgacctctt ggagcaagtt 29461 tctgcctctg gaaagggggc gggccctttt cacaacaggc tggttgtacc gagtaaacaa 29521 cacgatgcca tgaagaccct ggttcagtgt ctcgcacgtg gtagacactc agtaaatgcg 29581 tcctctgcct ggccctcctg ggtttgcccc agactcccct ggcagacctg gtcccagaca 29641 caaggtatga gagctccaag tcccgttcca gtaggtYatc caggtttatg gaaaggggac 29701 tgggtgtggg cagtcagctg cctcaggcag ggctggtacc ttgctccaga gcaggggctg 29761 agaaagccac ggaaaggcag acaccaccag ggcggcttcc acggggacct ggtcagaaga 29821 gcccagtgag gcactgtccc ctcctgtggc tacagagatg tgacccgtgt ctctcccagg 29881 acaatggctg cggccaaaga gcacactgca gacccagaga ctcttgcttt tacatccagg 29941 ctctgtgctc tggatcttca ggcaaatcct caccctcttg ggcctcagtt tccccacctt 30001 tctggcctag gtggtccagc tcagactggt tgagtatgtg gggtggatcc tcccagagtc 30061 tgtgagaata aaccaccccc tccacagggc aaggcaggtg gatgagatgt ggttctgttt 30121 gccctgagcc tcggtgattt ctggcaaatg caattctctg ggtaggacct tgtggttttc 30181 ttggtggcca ggacatcagt ggcagctggg ctccagcatt gtctccagcc cttgaccatg 30241 gacacggagt jtcccgggaca gttagagctg ggaacggtcc agccaggaag gacatctcct 30301 ttccttttcc tcgacctagc tcaccctgtg ctttcagggc cggggcaaca gttcccacac 30361 gctttcctat cagctgctca tcctcctccc aggcaggcca tttcactccc actcggtggc 30421 gtccaggttg ccagcatgtt caaaaccaga attcctgggt tcaagtccca gctgtgctcc 30481 ttagaagtag tgtgatcctg gggaagtcat ttcacgtctc tgagcctcag tatattcatc 30541 tataaagtgg gatgatgata acgctactga cctcataggg ctgttgggag gattaaacag 30601 tgactgtata tgtcaagtct cacaacagtg ctgtgcaaac attagctata ttattattgc 30661 cctcattcct gcagccctga cagtcagtgc tgccaccaca ggctctgagc tgggggtctc 30721 tctccaccaa atcccactgc catctgggga ccccaaacct ttttcacgtt gccactttcg 30781 ctactcagga aaattgacac tgagtccccg caaggagaag ttccaaaaag gcagaagatt 30841 tataggcctt tctcaccaca ctggcgcctg aagttcctaa ctgatcttcc agaagtttct 30901 aaataagact tcagctctca gctctcctct cttggtagat ccagtggggg cagaatctcc 30961 cctcagagtc tgtcctggac tgaaagatta ggggctgtta ctttaggacc agctcaaaga 31021 atcttctagg ctttgggaat catggctgct cgccacatcc actccagggt gcttgctcag 31081 tgtccaSgag gcccagggcc gatactgaaa actcagccat gggcttcaga acaagaccca 31141 gctgtctcag gctcttggct ctggcaagca ggatgtctca ctgtcacaaa cccagaattt

31201 tcaccaagga gaaggtgacc aggggaacag gccggagagc ggcctccagt gttgatgact

31261 gtttaagagc caaaatattc cagtaattgt gtgacatggg gatccctggc ccaaataacg

31321 ctgcaaccac aggaataKgc tcactgccag gaaaccagga aaccgatatt tggagcaata

31381 gacagactac tcttgtacag tggaaaagtc cttgcagaag ggaggaagat ggaaggggaa

31441 agcccaaaag cgttcctctc ccttcctgcc cctaaaatat agccctgagc tggacatgag

31501 tgcagcctca ggagaacttg acgaagaaat gttccataca ggaaattgcc tggcgaggcc

31561 attttgagtt agttatacca gctctgggct tcactcagga gaagctgtcc agtaaatgcc

31621 tgagggcacc caaggcctct gggattcagg ggaatgcacg ctctcctttg taccccttga

31681 ttttgttggc ccaaaagcaa gcctgctagc tcaaagagtg attcatttcc ccctgtgcct

31741 tctgggaagt tggattctgt ttttcaacaa ccaggcaaga aatgaagtaa ggcccaggct

31801 gactcgcccc ctcttctgtc cctacagagg tacatgggtg agtggattcc agggtggaag

31861 acaaacctga aagaaggcca aggtctaggg ttactatggc aacagcatgg cagggcgtgg

31921 tgatgttgaa tgaccgcggc cccgaagtga tgaaggagag agaaaggaag caggtcttcc

31981 tcaattcagc cttgagagtg aagcctcctt attctgatta atctcaaccc tccactactc

32041 aaaaatagtt gatggctccc tattgcctac aaaataaggt tcaaaggcct ctatttatag

32101 tcaaggccct ccctgatctg gtcaccccct gcctgttctg cctcagttcc tcctcttgct

32161 ctcatgtacc cagtggctgc agtcacagaa agtcttgttt tcccaggttt cctatagcgt

32221 cctacctcta agaatctgca ctctctcaag atctcacaga taccactcac ctccctaagg

32281 cagactgtca tcccaccatc aaacgtggtt gacccgataa gaatgtttgc ccccaccccc

32341 accatcccta ttagatagga catttcaaag gtggggacct gttgaccctg ctgaccctgc

32401 attccttcag ctcacctggc cccagtgcca gctggatatg agagaggccc aactgatatt

32461 tgttgcatga atgaatgaat aaatgaatga atgaatagaa aaggttaagc cagaagcaag

32521 gtcaccgagc tatttgttct gcatcaccac cccttgacat ggccctggaa ttgattgggc

32581 aaatatttag ttcagctcct cagatttcaa aatgcccttt tggagcatta aaaaaaaaaa

32641 aaattaaaaa gacttcatgc aggagatctt gcctctttag agcagtgcct gagtccactt

32701 ttcccgttgc tgctcccctg tggggtctct catttgtgtg gcccttgtta caccgctaga

32761 gaggtaggcc tctcaacagc agcaatgagt gctcggagga accgtgcctg tttgtgagtt

32821 cagaagttat cttccagcag gaaaacaaag tctttctgta ctttgcaact aggggaaaag

32881 gcagaggaag ccaatgtgag tggcagtgat gtagcctagt ggaaggtgac aagtttgcaY

32941 gactctagta aattggtgtg tagagaaatg cagcgtgggt ttattcggtt tttcattctt

33001 tcattcaaca tctagttaca gagtggggtt tggccatgtt tgagatagga gaaaacaaac

33061 tttttttcaa gttctcaaca ctacagttca cctctggtca ccaaaatgtg tgtgggattt

33121 ctccaaccac caaattgtcc agcagacact aactgggtgt cctgcagttc aattcaattc

33181 aattccaaca ctatctacct ggagataatg tYggatccca tcagttaaga gctctgtcgc

33241 acaagactgc ccctacttca gatgccagtt gcaagtagta ggctgtcacc tatactttat

33301 gaccaactgg ctataaagtg aggttcccac aactccctcc tcaggttcag ttcattagct

33361 aggagggctc acagaactca gggaaacact tacgcttact ggtctatttt attaataaag

33421 gatacagatg aacagccaga taaaagagag tcagagggcc aggtataggg tactgggcgc

33481 agagcttcca tgtcctccct cagtgtacca ccctccagaa gcctccgtct ttcagctgcc

33541 ccaaagtgcc caaaccctgt cctttttggg gtttttatgg aggtttcatt acacaggcat

33601 gattgattac atcattggcc actggtgacc aactcaacct gcagcctctc tcccatctca

33661 ggaggtcatg aggagggggg tgagctgaaa gctccaaccc tctaattcca tggttggttt

33721 ccctggtaac cagattcttt atgagcctac ccaggagccc accaagactt gcctcgctag

33781 aaaaaagatg ttcctgtcac ccaagaaact gcaagggatc caggagctct tcatcagatg

33841 ctcttgtcac tctggaaatt actaagctct cgggaatcag gtcaaagacc aaatattaaa

33901 caaacgattc tcttagtacc cctatctaca aggatSctag aggcactgtc tcaggtactc

33961 gagccagaga ctaaatgtat atttcttatt attaatatgt cacagtttca caggctgcta

34021 gccaggaagc cagagggacc tccccagtgt aaaatttgga ttcagacaag gctgcagtct

34081 cagcttcttc actaacaatg cactgtgggg caatcgcttt acctgtttgg gtcttaattt

34141 cctcacctgt acatggcagt gtcctctggg cacagagacc tactgcagct gtggcagtgg

34201 aaatgggagg atggacatgg gatccgctga agacacagac ctgggagccc ctggcttctg

34261 actccatgga gtgggtgaag ggcacaccag tctgcttcat ccctgactgc ctgggagtgg

34321 gcccttatcg aagaagaggc agaactaata tgaacagctc ctgtgctctg agcacctgca

34381 atgagcaagg cacggtgccg agtgcttgcc aggaggtatg aagaggccgc aagcatccaa

34441 gtatagaacc tggactttgg agccaggatg cttaaatctg aatctgaaat ccagcaatta

34501 ctgagtgtat ttgtttgcta gtgctgctct aaggaaggac cataaatgat gtggtttaac

34561 caacagaaat acattgtctc tcagttctgg aggccaggaa tctaagatca gtgaggaaga

34621 atctattcca cacctctccc ccagcttcgg aaggttttct ggcaatcttg aatgtccctt

34681 aaatgtagga gcatcacctc aatctctgcc tttctcctcc tgtggtgttc tttctgcgtg

34741 actgctggtg gccaaattcc tcctttgtRa aagaacacta gtaatatcgg agtaggggcc

34801 cactctactc tgttatgacc tcattttaac taattacgtc tgcaaggacc ctatttctaa

34861 ataaggtcat atcctggggt gctccaggta tgggcttcaa caYgtgaatt tggagggttg

34921 ggggcaattc aacccataac accgggtgag ggacttgggt ggtctctctg tgcctcagtt

34981 ccctcaccta tggaatggag atgacaatac ctaactcata aacctatcgt gggtgtttgc

35041 tgagttcctg tacgtaaagc acttaagcta gtggttcagc attagtgcct tacaaatgtt 35101 aactgctgtt atctcattca tcttttgtaa caactgtgtg ctgtgcaaca agggtgacaa 35161 ctggtatgcc tgccagagct gggcaggtca cacaaacaga cgaagtgggc tgccagtgat 35221 ggggcccagg caggtgagac agtaagagcc cccatttaaa ggcattctgc tcaacattgt 35281 tacataataa tctatggcat gaaactcacc tatggaggcg agagctcctt gttgctcttg 35341 atgtcaatgg aaaaaattga ccatgaccta cctggtcctt aggtggggtt aacagctatt 35401 ctgaaagaag aatgctgatt tgacaagaac tgggcgtgaa gccaaccatg tggtctagaa 35461 aggacacaat tgcctttaag ccaaggccta agcctatcaa gactgagtta atgaggctgc 35521 cccatcaagc cagcggaggt cagccctcac cagccctggc tggctctctg gctgcagagt 35581 tgctgagcag ggctggagaa cagaccaaat ggggccagcc aagttcgcac atcctcagag 35641 ccacccgctc aagtgtttag ctctcctggg gtgattgact tcagtgggag cgtggctctg 35701 ccatgattca gacttctggc ctccagaact gtgagagagt gaattcctat tgtttcaagc 35761 cacccagttt gtggtgatta attatggcag ccaactaaca ttcctctttt cctccaattt 35821 cataagaaca ggtgttgctc ttcttgacac tcagctgtgt gttctcttgg cctcctgctc 35881 cctgggggag tctccttcca ttaataacca cctttaacct ccctttcagc ttcttccccc 35941 aaacctggga agtccctcct tccaagccac agctccctct gccccacctc cttcccagcc 36001 ttctcatcaa gaagcaatct gccttgacca tctctttgac ttctcagcct gctggccctg 36061 ggctcctgct cccaccttcc cacccagatc accctggtgg attccatgga ccagtgacca 36121 tcctcatcta cttgaatgtt ctgctgcatc tgacactgac agtgaYatcc cttgtcctcc 36181 cttgtttact gccctggtcc tcctccttcc cagccatcat cacctttgtg agctctctcc 36241 ctctctgctc aggcttatgc cgagggtctc agcgttctat gcttcatcct cttctcttgt 36301 cctctccttg ccccaggaca cccctgatcc catgtgcttc cttcatttta tttcctgtct 36361 ctgttcttgc ctccaaatct ctctttagac ccattcacct gtgtcatctc tgccagcagg 36421 caccacaggc ccttcaggct cactaggtcc aaaactgaac tcatcatcct ccatacaggc 36481 ttccaaaacc tacccctcag ctcacaccag gtccattctc cttccttaat gtgtctcctc 36541 ctctccagcc tcacccccgc ttccttggcc cacaccacca tcatctctcg cttggattat 36601 cacagcagtg tcacttggtc ctgtcttgat ctccaggtga ccatacccgt gacagcccaa 36661 gataatttat ccctccttta cttacagaat gaagttcaac cctggttccc aacccagcag 36721 gacttccaag ccctccatct ggccctgatc tggcttctct ctgtcctccc ttcctcctct 36781 ctgatgggct cccggtgccc caccaccccc ttagcctgta ctgctatcac tcctgtggtt 36841 ctctcagccc aaaatgcagc ctcccactgc tgtgctgtaa gctattctgt ctgttcactc 36901 ctctccaccc agccagggct gataaaaacc tagacaaggt tcaaaaaccc agatccaagg 36961 tcaccacctt cacaaagctt ttcctattcc attcctctct ccaaccacgg gagaatggac 37021 cattcctccc tgtgtgtctt tattgtggag acatgtgtca gagcatcgac tctctatctt 37081 tagttcatct attgagatat tgatctctct tcttgaggcc aggggtattt tctgggacat 37141 ggttagatct caataaacat tgatactgga gggatgaaat gaaggaagga tggatagaag 37201 gctataagga tgggtggatg gataaatgga tggatggatg gatggatgga tggatggatg 37261 gatagatgga tggatggaaa aatggataga tggatgggtg gatggatgaa tggatggatg 37321 gatggatgga tggatggatg aatggatgaa tatatgggtg gatggatgga aggaaggaag 37381 gaaggaagga aggaaggaag gaaggaagga aggatggtag aagaaaggta gtaccagtat 37441 gctttagctc atgcaggcaa acagatgatg ggcagaggga agcatggtgg ctgattacag 37501 gaggatcata gcagatgttt aaggcaagat tgacagcccc acaaagactg agaagagaag 37561 ataagaaaaa tgggaaagtt attaagacac aagacctaga tcaggagcta gaagctggat 37621 cccagaacaa ggcaagagcc taatgactcg agtagccaac tcatcccagt ttgccaaggt 37681 ctttgccagt tttagcactg aatatcccac accatcggaa attactcagt cccagcaaat 37741 tggaatggtt ggtcacccta ctagtaatta agaccagtgc cccacttcag agcagaagca 37801 tcagccaggc cctgagtgac atcttgtagg ctcttgaact ggtctcactc aatccccatg 37861 aggcccaata ccatggaaca gagggcaggg aggctgaggg ccaagcagag gagcacctgt 37921 gctcagcagg gcaaggcatc acaggggcca acattggttt ccctgccctt ctcccagaaa 37981 ccacctcccc actttgatcc tttcccatgc cctgctaggc tctaggacac caaattctca 38041 tattctagcc actggccctc cctaggcagt caccctgggt gttatggact gaattgcttc 38101 tcccgcaaat tcttatgttg aagttttagc cctcagtgtg actgtagaga ttgggctttt 38161 agggaggtaa ttaaagttaa ataaggttat aagggtggca ctctaatctg ataagattgg 38221 tgccctttta agaagaggaa gagtaatcag agagctcgct ctcttcctct gcccaatccc 38281 tctcttgggg ggtgtgtgtg tgtgtatgtg tgtgtgtgtg tgtgtgtgtc cagtgtgggc 38341 tcacagggaa gaggtcatgg gcgaacagag tgaaggcaac catctataag tgccagagag 38401 ccctcaccag agaccaaccc tgacggcacc ttgaccttgg atttccagcg tccagaactg 38461 taagaaaata catttctatt gtttaagaca tccagtgtgt gtttaagcca ggccagtgtg 38521 aggtattttg ttacagcagc cagagaagac tgatacactg gggtgccatg cccccgagac 38581 tccttccaaa tctctccttt caaaacgcac caccctcaSt cctgattcct tcagagctct 38641 ttctgcatgg cagtgggagt catgaRttac ctcagacttt cccccaaatt ctcaagacat 38701 tccttaagat gtaagcttgg gaaacggcat gtgatgtctt tccctcgtgg gtggtcagag 38761 cacagacagc acacacaggc tggagacggc ccacaggaaa ggtgggctaa ccacctttcc 38821 caaagtagtt tcatctggaa cccatttggg cggtgttaca ctagtttctg atggctgctc 38881 taagaagtta tcacaaacag tggctcagac aacacaaaat tcttctttca tggttgaaga 38941 ggccagaggc ctcactgggc tagaatgagg atattggcag ggctccactc tttctggagg 39001 ctctagggga ggatccattc ctttccctct ccagcttcta gaagcttcct cactccttgg 39061 cacctggctc cgacatcaca ttgacttttc ccttcctgct tctaccatca catcaccttc

39121 ttctgactcc aatctcctgc ctctttcttg caaggatcct tgtgattgta attaggaccc

39181 agctggataa tccatgacaa tctcttcaag atccttaact taatcacatc tgcaaagtcc

39241 cttttgtcat agaacgataa cattcacagg ttctgggtat taggacacgg ataacttcgg

39301 ggttccatta ctcacccata actggtatgc agtgctgatt tccatcctgt aggtacggtt

39361 tagggatctc taggtcaatg agataatgga ctcttgctca tgttacatgg cataatggga

39421 , agaaagccaa acctagaaaa agagggactc aggttccctt gttagagcct cttcttacta

39481 actgtgggat taggggctga ttccctgacc tgctgtgttc tgtcttctct ccaattcaat

39541 gggaatgaac tgtgagggca ctgagcaaaa actaaggtct caatacctag tagtagtggg

39601 acttgcctct ggatacccag tagtgatcct gccgcctgtt tctggatatc ctacagtagc

39661 aatcccacct gtttctggat atcctacagt agtgatcctg cctgtttctg gatatcctac

39721 agtagcaatc ccgcctgttt ctggatatcc tacagtagtg atcctgcctg cttctggata

39781 cccagaagtg atcatgcctg gttctagata cccagtagtg attgtgtttc ctctagatac

39841 ccagtaggta ttgtgcttgc ttctagagat gtagtagtag ctggacttag ctctagatac

39901 ccagtgctca tctctagact gggctgagat cagtgtctcc cttgaagggt tattgtaagg

39961 atgaaaaaag ataatgcgtt taaagcactt ggtgtagtag gtggtctttt taaaagtgtg

40021 aataaatact agttcttatt atttctgtgg atatccaaca gccacataat tgggccccaa

40081 agccatgaag aaggaagagg aaatgtctta aaggttgtcg atggacagtg tttgctgaac

40141 atcaaaatca ctttccaggt attacctctg atttgctcta ccaactccac accccacctg

40201 cagccacata accttccatg atcacggcca tgcacaacac accatgtYcc ccaggcaagg

40261 ggaccttaga aacataacca ggcttgagac agcactctgc accggtRtct tggaaatgct

40321 cttaagagtg tatggctgag ttagggaacc aggatttcaa agtagaaagg gagaatctac

40381 ccaagcccat agaaatcctg aatccactcc tttctcagca acaagcactg gcctgggagt

40441 cagccactta tgcaccaacc ccactctgcc cctaattaaa tgcatgactt tgaaaattcc

40501 cctcattctt ctgagcccca attcagtgat tggtgcaatc acaggcttgg ctacagtgac

40561 ccattcattg caggcatggt gag ctctca atccctctca tttccactag aatctaactg

40621 ttgggatcta tgacccagtc agcatagcag gcctgtgggg agctctcagg ttcaagcata

40681 tgccccccct aatctacaag aaattagctg cagaaaacca aggaatagaa cctggaaaaa

40741 gagagggttt gctagagctg tccctttccc tgtctctgga atgccaacaa tagggaggct

40801 ctttggtctt gtctctcagg agtgcccatg ccattccagg aaaatgatgg cccagctggt

40861 ggYgtaaggc ttggggggca gcgagtgggc atcgtggtSa aagcctcggg atcagggagc

40921 tgcgtctgca ggcaggcctg ctggccggaa acctgccagg aaaggaaggg gctgtcYcgg

40981 ggcggggcca gggaggggtg gagacagggc cggctgtggt cagtgacaaa tgctggctgc

41041 aatccagcca gccctctgcc ctttctgagc ccgagggact gccacctcca ctgtgtgcac

41101 Rctcagctac gggacacagt aagtaccRat gccgcaaMgg gaggtcccca gggcttgagg

41161 gcatgtgagg cgaggagagg atggactcta gagttttggg gtttggggtc tgcaaagctc

41221 tgaaggagtc tcatctctgc agtttcaggt atccaaggca gcagaggtga gtgggtcccc

41281 cgagctctgt gaccttatgc tccacactaa ctctggcaga gcctccgttt cctcataggt

41341 aagatggaaa taattacacc ctctggatgg tgtgactgaa gattaaatac agcgggtgct

41401 ctcactcagc acatctggcc atgtctgcag acacatttgg ttgccacaac tggaaggggg

41461 gtgggggtta gtgacatcta gaggccagcg atgctgctga tgatcccaca atgcccagga

41521 caagatcaca aagcatcatc ctgttcaaaa ggtcaacagg atcaaggttg agagaccctg

41581 aaataaggcc atggggacaa aatgtcggct ggataggagg tgctcagtaa gtggcagctt

41641 ctgttgtttt ctgtgcctgg agtcttgggS ctttagaaat caggaacaat gatccaatat

41701 tatcggcttc cgtgagataa gggcatcttg cctggaggct gccacccagg ccggtcatgg

41761 cagctgctca tgaaggacag taacaatttg gcagtttgtt aaatgaacaa aatgtagaaa

41821 taaagtaagc agaattttta gtttttctga aggtagggct tttggccaga tatgcagcaa

41881 taaaagagca aactgcttcc ttgggccagt gtccttgctc atagatcagg aaaccgaagc

41941 atgaagaata caggcggcag atgcctgaag gtaacggacg tgttcatggt gctgacggtg

42001 atgataagtg acagatgtag actcatctcc aaacttgtca ggttatagac attaaatatg

42061 tgcaacttta tgaatagcag tcatgtctca atcaagtggt tttaataaag aaataatagg

42121 aagccagagc tgagagacag ggagggagtt gttcaaggtc acctggcaag tgagctccgg

42181 ggcggggaga gctcagctct gggtggccag cctggctttt tccactgctc agtgtccagc

42241 ttgcagtcta atgtctctga attacagaga aggagactgg tcagttcatt cattcattca

42301 ttctacaaag gtttatggag catctctcct gactgcaagc tcttgaaggt gagagcagca

42361 caaatgaggg tcccatggag agagaggccg gaatgaaaaa tgtcaatgac aaatgcatat

42421 ataaaggcac atgtgtaatt gaaagagctt tgagagaaag agtcaaggga ctgttccaga

42481 gaatagccat ggaaggggaa aaggtccagt gtgataaggt attgcaaaga agtgacattt

42541 aagcaaaagc ctgcagccta tgcagaagtt ggcctcagtg agaaaggttg ggggagggtt

42601 ccagtagaga gggaaggtat gcaaaggccc agagttagga cagaacttgc tgtgtttgag

42661 aaactgggaa aagaagagtg agcctggggg tatcacgtga tccagggcag agcaggtcca

42721 ggccaggtgc agccaggtca cagcagccct agtgggttag agcacaaatc aaagtttagc

42781 atttatctga aacacaggag ttggccatga gtttcttagg cgaggaagcg ctgtgaccat

42841 atttatgatt gaaggagatt cttttatatg ctgtatatag aaagcctttc agggcaaaga

42901 aaggaagcta ctggggtagc cctgggggag atgaagggag cttccactgg gggcagtaag

42961 aaagccaggg aaaggcggca gctttaagac ctgttttgga gatagaacgg acaagctttg 43021 ctgatgggct ggagtggaac aggaagtcaa gattacttct tctgggaagt tctgttcctg

43081 ggtctttagg atctagagga agctgtgact ttgtctctca tctctgcctg ggctccaagc

43141 ctcacatccc tttttgtaat tagaagatat tggacagacc gtcctcacta acacaattcc

43201 cacagctgag tccagggtag aactgggcag gacttcactg cccaacacgg gaaatatcag

43261 tcagcagatt tgggtttcgg ggatggtggt gggccagcgg gaagactgac cagggcctac

43321 ccatcacatc cccaccacct cccacctcaa ttcaccttgg cctgagatga caggtgaaca

43381 tgactgatcc tctctcttcc ctctgcagaa acactaaagc cagggaccag gagaggggca

43441 gcccaaccaa gctttcaaag cactcagtag aggctggtct gggggatggg aggctcccag

43501 ggcttcacct gtctctgtca aagccatgta tttccaccag aggcccaaga gtgcgatggc

43561 aaaccctgga tttgaaacta agaaacgtaa aacaagcact gaggactcca ctgcctcttg

43621 agtgacctct ctgaccctct gtttcttctg cactgttagg ataatgatac taactccatg

43681 ttgttgtaga gaagtataaa tgagctaata caggtgaacc gcctggggat accaggaggt

43741 gaggtcgagg aggaacgagg tatcactcct cagagccact cagagaSagg ctgtgcacga

43801 gtcagaggaa cctggatttt aattccggtt ccatcactca gtagctgaaa caagctattc

43861 cacttcactt agcctcagtc tattcaatct gtaaaataga gtgagtttac ttttggaaaa

43921 ctctgtaaaa tagagagctt acttttggtg aaggttaaac atagtaatat ttatggagtg

43981 tctagtatgt ctttaataat tagtggtttt actgaaaagt agagagagtt ggcccagagg

44041 gagcaagatt tctgggtctc aaacatgtag cccaggagag cctaagtgaa cctggggccc

44101 tctccaaaca gatcctgggg gagactcagt gcacacccgg agaagcagct cctccccatc

44161 ggatctctag tgcttggcag ggggcggggt cttgaggggg tgtccacaac acatggcaga

44221 ctgcagatga agaaactgag gcccagaggg ggtgaggctt gcccagggtg acctagtagc

44281 tgaatagatg ggagaatgga ggccagggcc tcactgagac tctctggtca gctgcccctg

44341 ggctgtatcc aataaggaaa ctcccctgct tctgaagctg ttctcgaaat tatcagctca

44401 gtgtgaccct gtggggggtt gagccacatt gtttctttag aagcatctcc atacatggct

44461 ggttccaacc cttggcagga gggaccatat tgtgctgtaa aatagactca tttagagaag

44521 ccggagatta aagcacccac ctatgtcctt caaagctctc caggcaagtg ccatggtggg

44581 aacaggtagg gagtgtcagt ggggggaagc ccagactctg ctcactcatt atctgcagat

44641 tagggctatt gttggtggct actaagtcag ggatttcaaa atcaggaaga tgcagccagg

44701 aaaagaggag gcaggactct gcagaggagg caggactctg cagagtcaga gtgataaccg

44761 agtctgagtc caagctttgc cagtgttagc aagcgactcc atctctctga acctcggatt

44821 acccatctgt aaaatagagc tagcagcaag atgtaccttt ttgggtggtg cagggctgaa

44881 ggagttggca cagtgcctga aagagggtgc gggcaatgcg cccaactgct gtggctgctg

44941 ggtttggtgc caggttcgat tctgcaggca gaaacttcta catgaggctc cttctcggaa

45001 ggagctcagg acacaatttg gaggctgggc tggcaagggt gacctgctgg agctattcaa

45061 cttcacttaa agacaggcct gcagtccaag cctgcccaat tcctgagacc attctctctc

45121 cactgctgag ccccacggcc actctgcaag ggatttccca cccacctgtt tggggccctt

45181 tggagtttgg ttttaattgg gtcacgggat gctgtgacag gctgcccctg cctggtgggg

45241 atctggggtc actgatgaca ttgtgcccat ggagagagcc cagcagaaag ggattccctc

45301 caaggcgaca cacagggcaa agctcacatc dgaagccagg caggccctct gcacctggta

45361 attagccRgc cYgggtgctg tcaggctcac acgtgtgtgt gtgtgtgtgt gtgtgtgtgt

45421 gtgtgtgtgt gtaaagcatg taccctatgg tacagttgag aatatggagg cctcagatgg

45481 ggcttttgcc agaaactgcc atgcctactg ctcacacttc catagcacgt gcccccaagc

45541 accccatggt gtaggtgctg ttattatcac tatcttacag ttatggagca gtggctcaag

45601 gtgtaactga Yttgcccaaa atcacactac aaggacacag cagggctgag atttgaaccc

45661 aggcagtggc ttcagagcct gagctgtttc ctactgcaga gggaggaggc aagacttcta

45721 cccgtagcca gatggggagg catgggcaca ggaaYggctc ttgggtgaag Yggagggagg

45781 aagaggagga ctgaaggcSa aggccacgtc aggagtgatg ggaKacccca caaaggcctc

45841 cctgagaagM gctagagaca aagatgagtg cctcctcatc tggaagatga aaagatgtct

45901 ttgcctgcat gggctgcYgt cacaaagtcc caggggctag ggggcttcaa caacagaaat

45961 ttctttcttt acaactctgg aagctggaag tctgagatta aggcaccagc aggatWtgtt

46021 ccttccaagg cccctctcct tggctcacag gtggctgcct tctccctgtc ttcacctggt

46081 cttccctctg tgcatgtctc tatcctgatc tcctcttttt aatttttgtg taaggacgta

46141 gtcatattgg gttggggccc actctagtga cctcattcta actcagtccc ctctttaaaa

46201 gccctatctc cagatatagt cacattctgg ggtattgaag gtaaggactt cagYatatgc

46261 attttggggg cacaattcag ccagaacagg aggacRgtgg ggatgtccac atgaagaggt

46321 tcaggcagaa ttcctttagg aggggaagat gtctctctgt gggacaaggg tggcatggag

46381 cagcccctgg gggaaggaga aggggac gt ttgcatactg gtattctgcc taccccaggg

46441 tggacactca ctcagcgttt gctgaatgaa cagggcaagg ccagcagtgc tgatggtScc

46501 aggcatgtag ctggtctgag ttcatagaag gaccacagcg ccctgccatg tgccaaacca

46561 ggacaccaga gtgaagRcca gaagctcaca tggaagcagc ttagttccct ggtaacctcg

46621 agatgctgat gagacagagc agagcagagg gaaccctctc cctccatatc ccatcctcca

46681 aaatgtgtcc cttgatgtgg atgggtagac aggattcctg ccctggcagc cagacccctg

46741 ccttgggtct gcacctcctc tccctccttc ctctccccgt catccctRaa tcttgtcctc

46801 Ragccactgc caccctgtgt aaaccctcat gYccagtctt gSgggtgcca tcccttctct

46861 ttRaagctga atggaccaaa catacccatt gagtgttggg tggggacatc tctggaaagt

46921 cagcacctgg accagctcca cccctctctg aggacacctt ctttcccttt cagaacaaag 46981 aacaKccacc atgcagctct tcctcctctt gtgcctggtg cttctcagcc ctcagggggc

47041 ctcccttcac cgccaccacc cccgggagat gaagaagaga gtcgaggacc tccatgtagg

47101 tgccacggtg gcccccagcR gcagaaggga ctttaccttY gacctctaca gggYcttggc

47161 ttccgctgcc cccagccaga Rcatcttctt ctcccctgtg agcatctcca tgagcctggc

47221 catgctctcc ctgggggctg ggtccagcac aaagatgcag atcctggagg Kcctgggcct

47281 caacctccag aaaagctcag agRaggagct gcacagaggc tttcagcagc tccYtcagga

47341 actcaaccag Sccagagatg gcttccagct gagcctcggc aatgcccttt tcaccgacct

47401 ggtggtagac ctgcaggaca ccttcgtaag tgccatgaag acgctgtacc tggcagacac

47461 tttcccYacc aactttaggg actctgcagg ggccatgaag cagatcaatg attatgtggc

47521 aaagcaaacg aagggcaaga ttgtggactt gcttaagaac ctcgatagca atgcggtcgt

47581 gatcatggtg aattacatct tctttaaagg taaggccctt gggcccaaac ctgcactttc

47641 tttggctttt ctgctgcttt tatctaaaga atacccaatt ccctcacata cataaaagac

47701 ggggagtacg ttaagttctt ttgggtgcct gttgagaaaa attaagtaaa caagcagcca

47761 gagaaggtaa gatgaatgcc ttcttgctgt ggatgggatt agtgaggctg agatgctgtt

47821 tcctccacgg aggaagagct ggttgctgtc ttcgggcccc tgRggacatc tgaagcccca

47881 gctttctaca ggctctgaag tatgaaccca ttgtggccac catggcaaag acaccaacac

47941 cttagccact cagggcagga cacagacccc agaagggctt aaagggcatt tcccagtccc

48001 ccgtatccct cagatcttgg cccctctgcc ctcatagagg ccaagactcc ctcagacaaa

48061 tgcttgttcc tctgaaatgc ctcctcctga ctYctcagca agagctgacc tctgcttatc

48121 tccccgacac tccttgtaag cattcctgct cgcctctgca gctcctgcca gttgctgacc

48181 ctggggaaag caagagtgga tagagaggag aagagaggag aggagagggt gggaagggtt

48241 gcgaaggaag gtaaattgtt aacacctccc cttcctatgg tcacagatca tgagtatctt

48301 tggccatttg ggtggctata acaaaatacc ataaactggg tggcttagca acaacaaaca

48361 tatatttctc atagttctgg aggctgagaa gtccaggatc aaggcactgg cagatgcagt

48421 gcccattcct tggttcatag agagtgcctt cttagtatat ccttgctgga aggaggaagg

48481 cagctctctg tggtctcttt tgtaaggaca ccgatcctgt tcatgacagc tccaccccca

48541 tgacctaatc aactcccaaa ggccccctgt cctaatacca ccaccttggg ggttaggttt

48601 caacatatga acaatgtggg gacacaaaca ttgagaccac agcaStgagt gtcgaacttg

48661 gactctgaga tttcctatcc cctggtgcag ggcagtcccc attacaccag attgctgagg

48721 gcagctggga aataagctaa ggacggtatt gactggggtc ttccttcgat aacgattaag

48781 aagttggaaa caggccaggc atggtggctc acgcctataa tcccaacatt ttaggaggcc

48841 gagatgggca gatcacctga ggtcaggagt tcgagatcag cctggccaac atagtgaaac

48901 cccgtctcta ctaaaaaata cagaaattag ccaggcatgg tggtgggcgc ctgtaattcc

48961 agctacttgg gaggctgagg caggagaatc acttgaacct gggaggtggg ggctgtagtg

49021 agccaaaatt gcgccactgc actccagcat gggtcacaga gcgagactcc atctcaaaaa

49081 gaagaaaaaa agaaaaaaaa gaaaaaaaga aataaaataa aataaaaaga agttggaaac

49141 aatcacttgt agcgttttgt tcagaagttc ccaWaggaag gtcagagaag ggtcattgaa

49201 gacttcccaa tgggaaaaac cattcatttc caggatccat actaacttct ttctaaaatt

49261 taaatcaaaa tattgSaatg aaagtgcaaa cagagaagtt cacccagata tcaggtagca

49321 ttcacagcca gccacatttt tcaccctctt cacttggaga tttggtcttg agtaaaacgt

49381 tagagaatca gagaacaYca gggRtccagg gcctctgaag atgtgaaaac caacctcctt

49441 gttttgcaaa tgtggaagga aaagtcccac gaaaagtcca agaatgtgcc caatgttata

49501 aagagacttg ccttcatatt caagaggttc aacagtcact gctctggggc tgccRtaaag

49561 atggtctccg ctggctatct ttactgtctt cactcctttt atttgcagct gagaatttct

49621 aattctgaca caaaattctt tttcattttt cccttttttc atctttagct aagtgggaga

49681 caagcttcaa ccacaaaSgc acccaagagc aagacttcta cgtgacctcg gagactgtgg

49741 tgcgggtacc catgatgagc cgcgaggatc agtatcacta cctcctggac cggaacctct

49801 cctgcagggt ggtgggggtS ccctaccaag gcaatgccac ggctttgttc attctcccca

49861 gtgagggaaa gatgcagcag gtggagaatg gactgagtga gaaaacgctg aggaagtggc

49921 ttaagatgtt caaaaagagg tactttcaga ctaccccagg gccagcctaa acccacacag

49981 ccccagggag acacacacgc cctaccaggg ccacacagca ctggtgggaa ggactcaccc

50041 agccaaggag ctgcctccag gcccagaggc atcctgtgac atccaagtcc tgggggccta

50101 gcccagttgg agggacaaga gctggaaact gggttcctta gggtggtgcc agagtgggca

50161 gagacctctg ggcagcccac Rtccaagtcc agagcaaggg gaggctcatc ctagaaaaga

50221 ggccagagga gccataacca ccattgttcc ttgggttaag gagtcctttt ttaaaaccat

50281 caaaactaag aatccagtgc attatgaatc caaggggtga ggctcagtgt gccaatgccc

50341 cagaacagtc taagaaagct ccttttccct ttccaggcag ctcgagcttt accttcccaa

50401 attctccatt gagggctcct atcagctgga gaaagtcctc cccagtctgg ggatcagtaa

50461 cgtcttcacc tcccatgctg atctgtccSg catcagcaac cactcaaata tccaggtgtc

50521 tgaggtgggt tcagaagctc ctatgcatct gcttcccaag Rtctattctg ttctattctt

50581 tctaKtctac tctaccccat ttcattccat tccattccac tcaactccac tccactccac

50641 tccactccag ttcactctat tcaattccac tccactccac tccagttcac tttattcaat

50701 tccactccac tccactccag ttcactctat tcagttccac tccactccac tccactccag

50761 ttcactctat tccattccac tccattccac tcctccactc ctctcatcca ctccactcta

50821 ctcctccact ccacatctcc actccactcc tccactccac tcctccactc cactcatcca

50881 ctccactcct ccactccact cctccactcc actcctccac tccactccac tcatccactc 50941 cactcttcca ttccactcca ttccactcct ccactccact cttccactcc actccattcc

51001 actcctccac tccactccac tctattctat tctattccat tccattctac tctattctat

51061 tccattccat tgcagtcaac tccactccac tctctactat tctattccac tcctctcccc

51121 tccactccat tccattgcag tccactccac tgcactccac tcctttattc tRttctRttc

51181 tattctattc tattctattc tattctattc tattctattc tattctattc tattctattc

51241 tctccctctc cctctctttt cccacaagta gtgaaagttt cactttgtgt cttatccttc

51301 atgtaatggg aagccatatc caccactgtt ccttgagtta aggagtcctg ttttaaacaa

51361 tcaaaactaa gaaggcactt cctagctatg tgRtctccaa aaaaYacttg actctctgag

51421 cttcctttct ctcttctata aaattgaaga attacacctt gctcaaagat gccatgagaa

51481 ttcaatgaca gacacatgcg aagtcacccc ccagcacagt gcctggggca gagtagctgc

51541 tccattgttc catttcctac ttgctccatg gctcagttga acagatactt agaggttgat

51601 gcccataggc agaagctttg ccatttgcta tgatgacttc acctgcccct Rgtggcctgg

51661 tgatgcctgg tgtctcccct gcagatggtg cacaaagctg tggtggaggt ggacgagtcg

51721 ggaaccagag cagcggcagc cacggggaca atMttcactt tcaggtcggc ccgcctgaac

51781 tctcagaggc tagtgttcaa caggcccttt ctgatgttca ttgtggataa caacatcctc

51841 ttccttggca aagtgaaccg cccctgaggt ggggcttctc ctgaaatcta caggcctcag

51901 ggtgRgagat gaagggggct a gctatggc ccWtctgtat gctggtagct agtgatttac

51961 acaggtttag ttgactaatg aggcattaca aataatatta ctctatgatg attgcttcca

52021 cccacacRac tgcaacatac aggtgccttg gggaaatgtg gagaacattc aatcttgccg

52081 tcactattca tcaRtgaaga ttaRcactga gatccagaga ggctggatga cttgctcaag

52141 ttcaccagca tggtagtggc aaagagaggt ccagagtcct ggcccttgat gcccagctca

52201 gtgccacaaa gctcaRtagg agggatgttc cagtggatga gggccaccag gaagcacagg

52261 tccaaggctg gtcccacact tatcagcagc aacaactStc agttcatcct gcatgggaaa

52321 aatgttggaa tgggagtctg aaatggggct actgtttcag tcctaaYgtg ctgtgtgaca

52381 ttgggacaac actttccctc tctggacctc agtttccctc tgtatacaag gatcagattc

52441 ttgctgtgac ccaagaactc ctgaaatcat atagaaaRgc tggggtgggc cctgtcattc

52501 Rtggttgatt tcaatacact caagtgccat tcatccttta agaaaaacat ctggatatca

52561 aggtggaaat ggcccattta atgattgatt atatcatttt gtggatatag ttataatctg

52621 atgggcctgg ctgggagtgg aagaagggaa gccttttgca aatagtagag tRtcagttgc

52681 aggtgccaat gactaacttt ttgaattcta tgttggcatt aacaataaag cattttgcaa

52741 acactggtta taactgtctt tatggaggca gctctgggaa tggtgacatt gatagcttac

52801 catgctccag gccgggtgcc tggcccttca cctggatggt cgcatttgcc cctcataaga

52861 ctcccatgaa gaaaggcacc actRttatcc catctgttat tcacagatgg gaaaggcaag

52921 gcttgaagtg gttaggtggc ttacccagtc acatatcttc taagtggtgc agccagaatt

52981 tggcgggggg agtgcgacca agaaccctac actcagtcct gtgctctgtg ctRtggagga

53041 gagatgacca ggagcagaaa cttcattcag ggRcatctca ggcaccagct cccccatgag

53101 ccagctaagt tccctccctc ccttcaccaa gcaccatgtg tttcctcatg tgccRaatga

53161 agaggattag atactcaaga atggaatgag tgggtgagtg agtccttcgc tgcacccaag

53221 tctgattttc tgtgcgcctg ctcaccccac cctgcatgtt ctaagcatgc ttccataagg

53281 ctgtgcccca ccctctgatt ctagagtctg gactgtatca gaggtgagtg cctactagag

53341 gtaacaaggt caggacccca aaccttgtcc atcccccRaa gtactgagcc cccaccatgc

53401 accagcccat gccagatgct ttgcacttgt gatatcaccc atcccttgac aacccagcaa

53461 gttctattat tgttcccatt ttacaggcaa taacataagt gctttcccag ggtcccacgc

53521 tggtgacagt gagggcccag ggtctgagag cccagatcgc acatgtgcgg gctggtggca

53581 ggggagatgg cagcaaccag actcagacat ttctctgcag ttgtgctgtg ggctcagggt

53641 ggctctttaY gaaggggccc cttcRtgggg tcatgcactc ctgtgtgYtt tcccttgcat

53701 catgccttgc ctgtcttggc aaatatttct ctggagttta cccagccagt ccaaggtcac

53761 agggaagccc tgtctgtgtc tcacacagaa ggtcaacgtc cagcactgtc caaactttac

53821 tcagcaaaca gtcacaaagc agctcctgtg tggggggtca ggggtgggct cactgtggtc

53881 tctgctgcat gtcacacatt gaagcactgt gctgggggtc atcacaggct gtttaactca

53941 attgtcacat gagcctgggt gcacaaaatg gtagagcagc tcagagagag atggacagac

54001 agcatgaacc tctgaggagt caggttttct tggatgaagg gacactaaga tggctttgga

54061 gcgtgagaag gacYtcacct agcaaatgtg ggaaaggagt gagacctcca ggcagaggga

54121 ctggctggag acgagcgtga tgtggtgagc catggagtgt atgggtcccc acagaacttc ₍

54181 agtctgggcc tgcacagggc atgtggagga gacaaggagg agggaggtgg ccgtgccggc

54241 ggttcagtga cagagatcct aaatgggagg ccaatcctaa atgggatgat ctctttcatc

54301 ccaatttcag ggtagtttgg tcatccacgc cacattccaa gtgtcccctg ggccctttct

54361 ctccctcacc cccctgtctg cacatgagta gatgcctcca Ygcagccctc ccaggacgct

54421 cacctctatc cacagatgct tctccaaaac ccaccaggcc ctcccatgga acgagctcac

54481 ctacagggta aaatcaggtc acggtcacat atagcctgac tactcccctc aggaccctca

54541 ttcacagcca ctgtattaat ttgctggggc tgccaaaaca aagtgtcctc atctgggagg

54601 ctgcagtaga tttgctgaaa ttgatttgct agcgttgctg aaattgattc aagcttgatt

54661 ctggagcttg aatcgaagat caaggcaagt gcagggctgg tttccctgag gcctctcccc

54721 ttggtttgca ggtggctctc ctctccctat gtcttcacat ggtcctcctc tgcatgtgcc

54781 tgagttctaa cttcctctcc tctcctcatc tMcaccagtc ttatagaatt agggcccccc

54841 aRtgacctca ttctaactta ataacctctt taaagtctct atctccaaat acagtcacat 54901 tttgaaatat tgagggttag gacttcagtg tatgaatttt gggaggaYgc aactcagcca 54961 ggctcactct tatcattaca gctgcactag tgccatgcct ggttcccagt ggacacccca 55021 ggaacagcca tccatccaga gtgatattct gtgacatccc ctacactcca cagctcatca 55081 catcacactc gtctccagtc ggtctgtctg cctggaagtc ccacacctgt tcccacatcc 55141 actgtctggg aggtcctttt catgcttcaa agccagctca gtgtcctcct ttgtacaaaa 55201 aaatgtcctg acctctcaga acttcattct ttctctcttt ctgtcgatct ttgtctgaac 55261 tcctctatca ttttgtgcac ccaggaacgt gtgacaattg agttgaacag gctgcaaaaa 55321 cgaaaaagaa gaaagaaatg ctgagttaaa caggctgcaa tgacccccag cacggtgctt 55381 caatgcatga aacgcatcaa tgacttgcag cagaggccac actcagcccc cctctgccct 55441 ttgagttttt gcagctcttg ccaagatcat tcttKttctt agaaagccca ccattatttt 55501 cctYtctagc catatggatt ctaaaagttc ctcttgtgag ctgtaatcag aatgcagaga 55561 agtaatacaa ggttagggcc caggactcYt tctcccacct ctccctgcag agactcagat 55621 ttttttaaaa aatgaccttg gtcttcRggg gaagaacttc ccaccacagt gaacagccat 55681 gcccagccta cacttgactg tgcggcttac ttagctcatc catccaaagg ctattcctgg 55741 gttgcctagt ggaaatccag gcatggagct agtgcaagca caatgataag agtgagcctg 55801 gcagacactg accccagcaa taatcaggta aacaaataaa cagaactaca aactatgatg 55861 acaagaattc atccatccac agatattcac tgaatggcca ctgtgtgcct ggcactgttc 55921 caagtgctga agaaaaatga agaaaacaaa aatccctgcc cttatagagg agacattata 55981 atgtgacaag ataacataat gaaaaagaat gaagaataaa atagaaaagt aaaatggatt 56041 gcatgtcact tgatgacaag tactgtggaa tgaggccgtc atctaaatgg agcacagaaa 56101 gtggaacatg gcgacatctc agccaaaaga cccggcagac accatcttgg ccaagggatc 56161 gaggttggca tcgccagctg tgagcagtgc tgacatctta ttatcttcga tatggcgtca 56221 tgagcaggct gcctcctctt ggtgggatct tcccccaaac ccagaacctc agtctaatca 56281 caagaaaatg acagccaatc ccaagttcag ggacatttgg caaaatagcc caccactcct 56341 acttaaaagt gtcgaggtct tgaaaggcaa gRaaaccctg ggaaatcgtc tttggccRga 56401 ggaaactcag cagacatgac gactaaatgc aatgtagaat cctcggacag aaaaggacat 56461 tagtRggaca gctggtgaaa cccaagtaag tccaggctgt accaatgtcc acttcccagt 56521 tctgaggaac atgctgtggt ctgtccacat ttacattagg agaagcaggg agagcgtata 56581 tgggacctct ctgtattgtt tttataactt ttctgtaaat ccaaaactgt cttaaaatag 56641 tttttttaaa ttatacttta agttctgggg tacaggtgca gaatatgcag gtttgttaca 56701 taggtataca tgtaccatgg tggtttgctg cacccccttt ttttaagaaa atgtttcaaa 56761 aagaaaaaca gccaagtagg ggagggcaca cgagtggggt tgggaattgc aaaggcagaa 56821 gcaggagacc agttaaggaa gaaaacgggg cactaagaga gacaatcagg aggacctgct 56881 gcagccaggg ccctgagggg ctccctgagg tggtgccatt gaagcggagt tctgagggac 56941 aatcaggtgt agacactgtg agtctcagaa gtgggaaaag gggagtgctg tgcacaaaat 57001 tgagagacgg tgcctgtggc agcagctgag gagggaaaga gaaggtgggg tgggaggccc 57061 atcccttcct tggccacaag gacactgagt agggtgctga gatgggagta acagtaataa 57121 taacaggcag cacttggagg ctgcgtcccg tgtgtctggc actcgcctaa gccctttgtg 57181 cacattggct gagttaatgc agaggtgaac tgagaggcac ctggggtagg ggctggggga 57241 caggaagcag gtgacatctc cagtcctctc cagcgtcctt agagcaggtc tacagtactg 57301 atccttctct gccacccttc tccaagacca ccttggtggg agtaaggggc tctaaggtga 57361 caacacacac aggagccaca gacacaagac acaagacact tttgactccc aggagaacct 57421 agtatgggca tccacacacc cttcctgatg gtgacttttt atgtagacat gcagagtgca 57481 gttaaccagc tgttcctgca cacatctgga ttgctactca cacatctgtg cacacacaca 57541 cacagcctcc tggagcactg tggcttctgg gtggctaaca cagctaccac ctctggttgt 57601 gctgagctga gcacccattg cctgctgggg tggggagagg gcaggcactt tccctgcgcg 57661 accccgttta accctctctg ccccactgat gtggtccctg ttgtccccga tgcacagagg 57721 aagaacctgt gtcaggaccc ccagagcggt gtctccacta agcagaagtc tctgtttctc 57781 tcctggcctc tcccagaggg gctgctctga agcatgtgga tttgatcagg ataatcaagg 57841 taaatgatcc ttatcttgat ccatcacaaa tgttaaggta caaggctgtg gagatggaga 57901 gtgggtggag tctctgctgc ccggtatcct aagctgggtg atcgcaagca gacacacaca 57961 tgaccacctc ttgggccatg cagggggaat gaatgtaatg aggccgatgt tacagggtta 58021 ttgaaggctc aggggagacc aggccaaaaa aaaaaaaaaa aaaaaagcta tgacctgaga 58081 cctccctata gcagtgtttc tcaaactctg attaacgtta cttgaggagc ttgttaaaaa 58141 tacatactcc tggccctgat cagataaatc agaatatttg acacagagtc tttaagctcc 58201 ccctcgggat tcaaatgcac acagattttt ggtgctttgc cgcctacagt acaagagagg 58261 gcaggactgt cctgttcagt gcactgtgac ccggacgctc aggcccacgg aactccccta 58321 ctccccctgc tccctgcggt gccacccacc tagctttcRt gcctgagggt ggtcctcaga 58381 ctcctcctag aacaggccca gaggctctta gctatgtaag tattcattcc tccaatcact 58441 gcagagcact caccaggtaa caagcacgca cacccaggcg agttccccat gctcgtcccc 58501 acgttgatat ctcagactct acaagtcttc agctgctgcc taggactctg taagtccttg 58561 agcttgggac ccctaccaca cacaagcgct gggcgtgccc cacaggcggg gaagtgctgg 58621 ccatatacac ccagtgaagt gggaattcca gataatgagt aactttttag caaagtaccc 58681 atgccctttg aattgtgagg tgtttttgtt tgctaaatct gacaattcta cctgtaggga 58741 acagggatga ttgagaagca gctgctccga tggccagaag ccaacagcct tccctgcaga 58801 gatgcgggaa gtcccaggga cagcaggaaa gtccaggcac tgcactggca gtgggattgg 58861 ggcttgggtc agaagagggt cagggccaca aggaaggacc ctgggaggct tcctgctaca 58921 taatatgagg gccgggagca taacaaagga ttgccttatc catgattgca tcatcaaact 58981 gaagcctgag acagaacatt ctgtgaggtg gccttgttca ctgcagagga gctgactcac 59041 acagttttgt ctgggaagtt gcaacctgtg ccaggagtag ccagcctggg agtaacaaag 59101 aggcttttct actgcaggtt ttcctagagc tcctctccct ccctcccctg gccaaaggtg 59161 agctctgcag ggagggtccg gctctagggg actttgctcc tgggcatcct agctgcagag 59221 attggtgggg cttgtccaga aaggggggtc ttctggacct ggggatgatg cagttgggcc 59281 tcagggtact gggaggccag taggggtgct tcaaactggc cagtaacctg aaggactcat 59341 attcttaagg atatcctggt ggccacgtag aaaacagtca ggtggggtga gggtggaagt 59401 aaggaccagc tcagaggtca ctgagggtgc agccagacag gctgggaccc acgtgggcag 59461 cagaggtgga gagtagggat gtggaggggg agacccagcc ccacgctggg ggccctgagg 59521 ggaggtggag gctgagccag gagaagaggc accacccact cacttcctgc ttgctgaatg 59581 actgtgagga gcaggagaag gagcaaaaga gcaagtgagg aagtcaaggg ggttatttgg 59641 gggcaatgct ccatgtgagg gtagctaagg acaggtgcca aggaggcccc tgtgtcaaaa 59701 tcccaggtca aaatgttagt taccagagac ctctgataaa gacagagcca caggtaaaac 59761 gcagcggcac aacccctcga ccctaaaatc agaagcctat ctgtgtcctg gcaaggagag 59821 aagcacgagt gatcatccac accgccagga cgcaagcccg ttatttctga tgcaaaaccc 59881 aggctccctc cagggctggc acagaggact gccagaggag tcagggggcc tccaccttcc 59941 ccagctgcgc aacctcagag ggtgtctcct tatctctggg gtcactgtgt cttcatggcc 60001 aggctgggca caggtcagct gggagtggag ctgtgtttgc agggaaggaa cgagggtgga 60061 cgtcgaagcc aacctgcctg gttcagaatc ctggctcagc ttggcactta ccagcagtgg 60121 tggtgaggcc ttgggaatga gctccgcctc cctgtacttc cgtttcctca tatctaaaat 60181 tgagggagta atgggacccg cctcagtggg tgttcatgtg gattccatgt gctcttaagc 60241 ataaagaaca gagcagctat gatgaccatc atctatgtca ctgggcctcc ggaagtgagg 60301 gaaggagagg cagatttgct taagtagaag gaaggcggag gaaggtagta aggcgtcagc 60361 catgtggcac agattgtatt atgagattta ctggttttct tacttcgtcc tcaaatttcc 60421 ctccttaccc acttcccatg attcctgaga gtcaagagga cgggagctgt ggaatgtgtt 60481 agtcatctac tgctgcagag taaatagccc atgattatct cacggagttc ctgagggtca 60541 ggaatccagg attgctgttg gccagggcaa tcccagaagg ctcacttgtg gggctgttgg 60601 tagaaggtct cagttcctcc ctatgtgggc tactcacagg gctgctcaaa tgtgacttag 60661 agagagagag agagagagag agagagagag agagagagag gcttgtttgt ttagtgtcca 60721 ggaccgagag aggatataga gagaaagcac aaaagagaga gagaaaaaaa gagaaaggca 60781 gagagagaga tagagacaga gacacagaca gttgttgaat gtccaggacc aagagagaga 60841 caaaagacag aaagcacaaa atagagggga aaagagaaag acagagagag taagggacag 60901 agagaggggg acacagagag agaacccatg gcagaagcag cagtcttttt tttttttttt 60961 ttttttttga gacagagtct cactctgtcg cccaggctgg agtgcagtgg cgtgatctcg 61021 gctcactgca agctctgcct cccaggttca caccattctc ctgcctcagc ctcccaagta 61081 gctgggacta caggcgcccg ccaacacgcc cagctaattt tttgtatttt tagtagagac 61141 ggggtttcac tgtgttagcc aggatggtct cgatctcctg acctcgtgat ctgcccgcct 61201 cggcctccca aagtgctgag attacaggtc tgagccacca cgcctggcca gaagcatcag 61261 tctttttata acccaatctc ggaaatgaca ccccacccct tctgccttag aaagaagtca 61321 ctaagtccag tccaatgtga gagaaagtaa ttaagctcta tctcttcaag gaagtggtat 61381 cagacatttg tggacacatt tgtaaaatga ccagagcgtt agaacctcag aatccagcag 61441 actaattgcc ctcatagtag attattaatg ttttaaaaaa tggatggact agctgaagga 61501 ataaatgaac gagtgagtga gcaggatatt tctgtctcat ttcacatgca gaaaaggcac 61561 tgaggctcag aggaattagg acatgtgtga ggttctctag gcagtaaggg gtgggggctg 61621 gcctggtttg ccagaactcg gagatgcagc atgcagcgtg cagcagttct gaaatggaag 61681 ccagggatgg caagctacag cagccactcc ctcccggagg gagaacggac ccaacaccaa 61741 ggaggaaggg atgactcagc agccctcaaa acagagtcag gagttctccc tgcttttgcc 61801 aaaccctctg caggcacctc ttatccatac agggacgcag ccaaaggcct agctgtgctg 61861 aaggaaattt gcaaatcctg cctcaaatct gcagccagta tctcccccag cagcctccaa 61921 accaggccag cacgaaccca gccagagagc agcataggtg ttgggcaaaa acaggctatt 61981 gactccatcc ttttctaaca gagaccagag tcctctggcc ttccacagag aaggtggggc 62041 cttctcaggg ttctctggat ctgctggtgt cagtcagtat ctatttcttc ttcctaagaa 62101 ttcttttttt tttttttgag atggagtttt tgctctgttg cccaggctgg aatgcaatgg 62161 cacaatctca gctcactgaa acctctgcct gccgggttca agggattctc ctgcctcaac 62221 ctcccgagta actgggatta caggcaccca ccaccacaca gggctaattt ttgtattttt 62281 agtagagaca aggtttcacc atgttggcca ggctggtctc aaactcttga tctcaggtga 62341 tccacctgcc tcagcctccc aaagtgctag aattacaggc atgagccact gagcccagcc 62401 tcctaagaat tcttaaagga gctacggttg acaaaagagt ttcagagagg taaagttatg 62461 gccctaaagt cacccagcaa gtagatgtgg caaagccatg ttgcaaaaga agccctggtg 62521 ggtgacactc ttggatggc ccctgcctct ccggaaggca ccagcgttgg tttctctccg 62581 cctcaccttc ccatgcaggt gggcacgttt gtgcttgggc tcctgctggt tatgccccag 62641 aagcacactc ttccctatct gcagtcccag cccatgtgtg gacacaaccc atttcctagg 62701 gtgttcctta gcccactgca ccaagtcagc atttaggaat caagagtggc accacaaagg 62761 caatagctgt gaagaccaca agcagcatca cagtgatcaa gcttgcagaa ttccattgtc 62821 tgatggactc tgtgtgtacc aaggtgactg caatccaggg acagtgagag tcactaggcc 62881 ttggactaag catctgcttg tcccaggtcc caggctgaac atttgatgtg aatctttagt 62941 ctcttcactt ttgagacagg cactacagcc acactcacac aggtcccaaa ggccagtgcc 63001 acccactacc tctgccatct ccactcctgc attccaccag attccctgac ctttagaaat 63061 agtctcctgg aggccaggcc tgctggctca agcctgtaat tccagctctt tgagaggctg 63121 aggtgggcgg attacctgag gtcaaaagtt tgagatcagc ctggccaata tggtgaaacc 63181 ccgtctctac caaaaataca aaaattagcc aggtgtggtg gcagtcacct gtaatcccag 63241 ctactcagga ggctgaggca ggagaattgc ttgaacccag- gaagtagaga tagtagagat 63301 tggagtgaac tgagatcatg ccattgcact ccagcctggg caacagagtg agactccatc 63361 tcaaaaagaa aaaaaaaaga aaagaaatag tcccctggag cccctggccc tgacctccca 63421 aaagccagag tgaactttca atctcaccgt aggctgaccc cctgtgtcca ttttaagYca 63481 gaggactata cccatccaca gtcaaagaag agggtggtga ccaatgtgga caaagctccc 63541 attcagctga gaccccaatc agtaaagaaa atctttccct acacagatct acagacaacc 63601 aaagccttaa aaaggcatca accctaaagc ctgtgaaaat gtgattttct ctcctgtgtt 63661 caagaatgga aatgccttcc ttcattttta aagaaggagc aggggatggt ggtgagagtc 63721 tggatttggc attggattgg tctttcctaa actccaacag ctcctgcatt taacagctag 63781 gggtatgtgg gcaaatcaca tgattagaca taggaagctt tttcctcctt cctactcccc 63841 ttcctggagg ttgacacaga ccaaagcttg gtaagaaaac ttaggataaa agaaggggca 63901 gaggccgggc aaggtggctc atgcctgtag tcccagcact ttgagtggcc aaggtgcgtg 63961 gatcaattga gcccaggtga ttgagaccag cctgggcaac atggtgaaac catgtctctg 64021 caaaaaatta caaaaattag ctgggcatgg tggtgtgcac ctgtaatccc aactactcgg 64081 gaggctgaag ggggaggatc acttgagccc aggatgttga agctgcacat gaggtgagat 64141 tgcaccactg cactccagct tgggctacag agtgagtccc tatctcaaaa aaaaaaagag 64201 ggcagagatt tttttcaaca tcatcagaga tgggagctat acaagatata caaagagagg 64261 agacagtcag ccatggcaat gtcaaaatac tcgttagcca gcacatgttc tgcctaggga 64321 attttctgca cctactggga ggtatgggga aaggacacag ggtttagcag gatcaagagg 64381 ttgtggggga tgcagagtac aggacagcaa tccccagatg gccttggcct tggctctcct 64441 tcctccaact cttagctctc aggataactg tagaatatgc taagaatgca gtgccctgag 64501 acaaggagaa aatatcagga acaatctgag ctttgtcttc attcctccta aaacttgttt 64561 cagccatcca agtgacttct gagatataaa acccagggag gggtgttttt gaggcccctt 64621 agctgtggtg caaagtgagg cacatgcaaa caagacccca tctgccgggg cagctttcct 64681 gagccttggg ggactggttc accatggatc ctaggcgtct gttgattctt gctgcctata 64741 tctgtaatga agttggtttg cgtggcttgc atagtattct gtcacatcaa actcatactc 64801 tagcaactgg gtttgtgtaa aacctcctcc cacatccagg aaattaagca gaaattagca 64861 agatgcttag agtcctctct gaggagcgag gcaggtgcac agtgttgggg acatgttggg 64921 agtcctcccc ccagattgat aaccattgca tgggactctg cttcccagag agaagaaaga 64981 gaagatttca atcaggaagg ggctccctgc aatttcaagt agggcaggat ggagttgaga 65041 ggtgggatgg aagcaatgaa attaacttgc atttcaaacc tctgggggca acgcataggc 65101 ttgaagctat aatgtgagcc tgagctaaaa cagtaagggt gtttattcag tattctggac 65161 tccatatgta tctgatcact tcacagctgc ttaaggagat tgtccagggg tcggctaact 65221 agacccactg gccaaaccca ggcccaaaac agacagcttt taaatatttc acaagctaag 65281 cttcatacat ttttaaaaga ttatgaggaa gaaggaagaa aaggagaaag acaaagagga 65341 gtcRggggag aagaggagac agagatcata tgcgaccatc aaagtctaaa gcacttacta 65401 tttggcccat tacagaaaaa agtttgcaga tccctggaat gtagtccctg ctcccttcca 65461 ttaaggccac tgccccaaaa ctgcagagac agtgtcaccc tgagagtggg agcattattt 65521 gttttgctcg ttgctggatg cccagtgcct aggatcatgc ctggcacata aaatcactct 65581 gtaaatattt gtggaataaa ggaaaaaata aatgaatgaa caatgtatag aaaagcactt 65641 ggtaacctat aaagtccaag tataggacaa ataaaaatac atactttatt tatttatttt 65701 aatttttttt tgagatggac tcttgctctg ttgcccagcc tggagtacag tggtacgatc 65761 tcagcccact gccacctctg cctctcgggt tcaagagatt ctcctgcctc agcctcctga 6582Ϊ gtagctggga ctacaggcat gtgccatcat gcctggctaa tttttttgta tttttattag 65881 agatggggtt ttgccatgtt ggctgggctg gtcttgaagc cctgacctca ggtgatccac 65941 ctgccttggc ctcccaaagt gctgggatta caggcatgag ccactgcccc cRgcctacat 66001 actattttaa atccactgca cctgttctta ttctggagtg gatgctgaat tctgcccttg 66061 gacaaggccc tcagtgtgtt ctgggagagc ctggcttgaa gccacattat gaagaggcag 66121 ggcagatccc aacccaggaa gctggagaca gaggaaatct aaaggcagga acctcctaca 66181 gaggttgctc ttctgcttag cctaagaagc agagcttctc aggctttctg gtgcacacag 66241 atcaccttgg ggttattatt agtatccaaa ttctaaatta gcatgcctgg gctgggcccc 66301 aagaattagc atttctaaca agctcttctg tgttgctgca gctactggtc cctgaatcac 66361 atgtgctgta cagcaaggat gtcaaagctc tcttcctcaa aggcaggagc atctcctcag 66421 accctagtat cctcctcatt tcctctttgc ttccttttgt cgggttccaa aaaacagtag 66481 aagtgccctg gattctgatg agagaacatt ctcaagggat tgctgactcg ggaggcaaac 66541 aggctccagc gatcctgcag cccacgggct ggtggggaga tgacccacag ggggctgttc 66601 caaaaaggaa gagcagtggg cctggaagag tatgatttgg ccttagtgtt gcttcacttt 66661 tctgtcttaa ttgccctgtg gtttcatctg gtcatgggag tccacgatga catgtgccat 66721 ccttgtatga atggtgcttg cagaaccgaa ggaagggcct gtaccaatgc ctggggaaaa 66781 gcagaccaat gaagacttgt aagagcccag aaaagaggct gggagaaggt caggaatggg 66841 gtaaacgtgg ccttggggca tctgcctgga gctccaggtg accagtggca cccagaacaa 66901 ttcttgaccc tctgcaggtc ctccaaagca tcctcagtag gacctgcaga aggtcaaaaa 66961 ttttctgctt tcacgttgga tggaggtcaa gactaagtca gctcaactgt aaagaaaatg 67021 atgcttttcc ctttgaaaac tggtacaaga caaggatgtc ctctctcacc actcctattc 67081 aacatagtat gggaagttct ggccagggca atcaggcaag agaaagaaat aaagggtatt 67141 caattaggaa aaaaggaagt caagtctcta tttgcagatg acatgattgt atatttagaa 67201 atccccattg tctcagccca aaatctcctt aagccaataa gcaacttcat caaaatctta 67261 ggatacaaaa tcaatgtgca aaaatcacac gcattcctat acaacaataa cagacaaaca 67321 gagagccaaa tcatgagtga gctcccattc acaattgcta caaagagaat aaaataccta 67381 ggaatccaac ttacaaggga tgtgaaggac ctcttcaagg agaactacaa accactactc 67441 aacgaaataa aagaggacac aaacaaatgg aagaacattc catgctcatg gataataaga 67501 atcaatatca tgaaaatggc catactgccc aaagtaattt atagatgcaa tgctatctcc 67561 atcaagctac cactgacttt cttcacagaa ttggaaaaaa ctactttaaa tttcatatgg 67621 aaccaaaaaa gagcctgcat agccaagaca atcctaagcc aaaagaacca agctggaggt 67681 ataacactac ctgacttcaa actatattac aaggcttcag taaccaaaac agtatggtac 67741 tggtaccaaa acagatatat agaacaatgg aacagaacag aggcctcaga aataacacca 67801 cacatctaca accatctgat ctttgacaaa cctgacaaaa acaagaaatg ggaaaaggat 67861 tccctattta ataaatggtg ctgggaaaac tggctagcca tatgtagaaa gctgaagctg 67921 gatcccttcc ttacacctta tacaaaaatt aactcaagat ggattaaaga cttaaatgta 67981 agacctaaaa ccataaaaac cctagaagaa aacttaggca ataccattca ggacataggc 68041 ataggcaaag acttcatgac taaaacacca aaagcaatgg caacaaaagc caaaattgac 68101 aaatgggatc taattaaact aaagagcttc tgcacagcaa aagaaactat catcagagtg 68161 aacaggtaac ctacagaatg ggagaaaatt tttgcaatct atccatctga caaagggcta 68221 atatccagaa tctacaagga acttaagcaa atttacaaga aaaaaacaaa caatcccatc 68281 aaaaagtggg cgaaggagat gaacagacac ttctcaaatg aagacattta tgaagccaac 68341 agacatatga aaaaatgctc atcatcactg gtccttagag aaatgcaaat caaaaccaca 68401 atgagatacc atctcatacc agttagaatg gggatcatta aaaagtcagg aaacaacaga 68461 tgctggagag tatgcagaga aatagaaatg cttttacact gttggtgggt ctgtaaatta 68521 gttcaacctt tgtggaagac agtgtggcaa ttcctcaagg atgtagaact agaaatacaa 68581 tttgacccag caatcccatt actggatata tacccaaagg attatacatc atgctactat 68641 aaagacacat gcacacatat gtttattgtg gcaccattca caatagcaaa gacttggaac 68701 caacccaaat gtccaccaat aatagactgg ataaagaaaa tatggcacat atacaccatg 68761 gaatactatg cagccataaa aaaggatgag ttcatgtcct tttcagggac atggatgaag 68821 ctggaaacca tcattctcag caaactaata caggaacagg aaaccaaaca ccacatgttc 68881 tcactcataa gtgggagctg aacaacgaaa acatatggac acagggaggg gactatcaca 68941 cattggggcc tgttgggggg ttgggggctg gcagagggat agcattagga gaaataccta 69001 atgtaaatga caagttgatg ggtgcagcaa accaatatgg cacatgtata cctatgtaaa 69061 aaacctgcac gttgtgcaca tgtaccccac aacttaaagt ataatttaag aaaagaaaga 69121 aagaaggaaa atgatgctct gaggccggag aacttgagaa cactcagata atgctctgag 69181 gcaagatgac tagtcatccc caatgtccac tctctttgtc tctctcatgg taatggaact 69241 ctgaattttt agctgggagg tggctaccta gaatcttgac tgcactgcac agcctccttt 69301 gtagctaggt atggccatgg gacaaaactc caggcaacac aacacaagtg ggaatgacag 69361 gcaatgttca aggcattcct ttcaaaagaa agggtgtgcc cttcccttcc cctgtggccc 69421 tttctatgga ctggaaggtg gacatagcag tgagccatct tagcctagac aaacagacgt 69481 ggaggggcag ctgagcaacc aSacaggagg acgtggtttc tgacaacgtg gaggcaccat 69541 atcaacccac tgcctccagc tggacctgca ggagagggaa atgaacttca gtctcatttt 69601 agcaactatt tctttaggat tctgtgtaac ttaaacatat gtattggcca ggtacagtgg 69661 ctcacacctg taattccagc actttgggag gctgaggtgg gaggatccct tgaggccagg 69721 atttcaagac tagcctggac aacacaatga aaccctgcct ctacaaaaaa ataaaaattt 69781 aaaaattagc caggcatggc gttgtgcacc tatggttcca gctactcaga aggctgaggc 69841 ggcaggatat cttgagtcga ggcggcagga tatcttgagt ccaggagtca gagtcttcag 69901 taagcaacga gcaatgattg cgccactaca ttccagcctg ggtgacaaag cgagtctctc 69961 tctctctctc tctctctctc tctctatata tatatatata tatatataat atatatataa 70021 aaatatataa tatattatat atgtgtatac gtatatatgt atatatatac acacacacac 70081 atagagagag atatatatat aaagacacac acacacacac acacacacac acacacacac 70141 acacacacat tcaattccaa aactgggagc ctgaaagtca tttaagaaag atgggcccag 70201 acagttattg gtcatcttag tgccttacag tcaacaaata tgtaagtcct ctaaagatgc 70261 agcactatcg caacagacaa acaaaaaatc ctgtcctcgt agagtgtaca tttaatatca 70321 tttcatttca tcttgattac cactctgtca gggaatattg ccttgcatct tagacatgag 70381 gaaattaagc tgtagagatt tcccatgatt tgtttgaagt gagtcagttg gtgagtcaga 70441 catcagagat tcaagccagg tcagctcatg ccagagctag aacctcgcca ctggtctggt 70501 ggcctccaaa gcatgccctc tagagaggcc tgtcagggct accccggatg gggactgtga 70561 ccatgaggaa tcaagaggaa ggattttttt ttttttgaga cagagtctct ctgtgttgcc 70621 caggctggag tgcagtggcg tgatcttggc tcactgcaac ctctgcctcc tgggttcaag 70681 cgattctcct gcctcagcct cgcctcccaa gtagctgggt tacaggcatg cgccatgatg 70741 ccctgctagt ttgtttgttt tttttttttt tgtattttta gtaaagatgg ggtttcgcca 70801 tgttggccaa gctggtcatg gactcctgac ctcaggtggt ctgcccacgt cagcctccca 70861 agatgctggg attaccagca tgagccacta gtcccgccca ggattttttt tttccttttt 70921 catgagccaa agaaagaccc cagactagct aagagagagg cccaaggata cctgaaggcc 70981 ggggaggagg gacaaccact tgttggggtg aaccaatcgc agaggctcag caggacagag 71041 gccaaggctg aggaggcccc cacagagaaa cagagcctga ggacaagggg ttcctcacaa 71101 cacctgtgct ccccgaaagc tcccctccac acccctctct aggtgcccta ctctctgggg 71161 ttggtgaagg ggtgccaaaa atgcaaactg atccacagaa. aaatagagtc ctgtatttta 71221 aaaatatatc taggtttgta tatggacatt cacatcacac agacacacag acacacatgc 71281 agccacacac acacacacac acagagacac caaagaaaag tgctttagaa atacaccaaa 71341 atgtggctgg gtgcggtggc tcatgcctgt aatcccagca ctttgggagg ctgaggtggg 71401 cagatcacga ggtcaggagt tcaagaccag tccgaccaac aaggtgaaac cctgtctcta 71461 cgaaaaatac aaaaattagc tgggcgtggt ggtgtgtgcc tgtagtccca gctactcggg 71521 aggctgaggc agaaagttgc ttgaacccgg gagtcagagg ttgcagtgag ctgagatcac 71581 gccactgcac tccagcctgg gcaacaaagc aagactctgt ctcaaaataa aaataaaaaa 71641 taaaaagaaa taaaaaagaa atataccaaa atgttagctg gggtcttctc tgggtagtaa 71701 agtgctgggg gatattttcc aaagtccttc tttacattct ctgagttttt ccatgttctt 71761 caatgagtat ttaataagca gataaaaact aatacaacaa aggatttttt ctgtgtgctt 71821 ttttgacctt tggaggaaga gattagagct agtcccataa ccaggttatt tgagtaggtc 71881 taacaagccc gtattaccag aaattatcat ctggtcattt ccagtccgag aacagaacac 71941 ttggttgtcc tggcatttcc caagcagKgg gaggagttct ctgcaggaat aaataagcct 72001 cagcattcat gaaaatccac tactccagac agacggcttt ggaatccacc agctacatcc 72061 agctccctga ggcaggtaat ccatgatgtt ttacatcctg ggagcggagg aatctgtttt 72121 tccaggagag ttttaggcag cagcctggag tgtgtggagt gtgaggggta agcagaggcc 72181 aggaggaggt gtactcaggt gttaggggcc aggggtctgt tcttggctgc cactgattcc 72241 ctgtgccttt tttagaggca tcctctgtgt ctgggttttc acacctgcaa agggtggagg 72301 tgccctgggg cctctatggt catttctgcc ttgatactta cagattcgga tttgagtcag 72361 ctgtgcatct gaccctcagg gaagaggtgc tgtccccttg cctggagcag ggtgcagctc 72421 tcagaacatg tggcagatgt gattattgca gcaggtccct ctgagcagag gccacaggcc 72481 tcaccatgat ttcagggtct ccatggggct gcctcgggag ctccacttcc ccaaaaggac 72541 ccctggccaa gtcgacagat gggctgtgtc tctgtccagc aacagaaaag acaaactgct 72601 gggaaacagc cagccctcca acttgcccaa acagaaaaga caagcctttg cccctgaaat 72661 aattctggag aaaaatattg tctaacattt atccagagaa atgattgcat cagcctgaga 72721 gtgaacagtt gaagcaaaca aggtgcctct gtccctgggc ttggccaaag gcatttccac 72781 tggcctcccc tccttcccct ccttcccctc cttcccctcc ttcccttcct ttccttcctt 72841 cccttccttc cactctctct tccccttttc ttctcctctc tctacccctc tcccctcccc 72901 tcccttccaa tcgcctctct tccccactct tctccccagc acccaagctg ccccttttct 72961 cttctgaatt ctaggactga gtgggcggag gctgaaggtg aataatcttg tttgctgcgg 73021 tcaccggctt ggaactcagc ccttccaggg tctcttgtgc agtagctcat ggctcttctc 73081 tggcttgtag tttcaggaaa ggggtagtat gggaggtggt gactgctcgg tacgtctaat 73141 atgaaccagg tgccttcatc atttatctca cctgagccac ttaacaggtt gtgcagagac 73201 ggaaacaggt tgagagatgt acagtcacct gcttgccagt acacagcaat caaaagtggc 73261 caaaataaaa tcccagtcca agtctgggag actccaaagc cctctctgcc ttctccccac 73321 taagaggccc ttccaggctt atggtggaca cagacaccac gtggcaacct ggcaggggca 73381 gagaagaaca tttgcctttc tttggtcttg ctgccaacca ttatcagggc catcgaggct 73441 ccagacactg taccagggac tttcatttcc ctctctcagt cgaccctcac tgccacccag 73501 catcacatcg tggaggcctg tggaggccac accacgtgac atctagaggc tgggagagtc 73561 actgtggcct ctatctctgc ccagggctcc ttcatccctg ggttctactt tggtggcagt 73621 tgggagaatg aaggaaggga gcccctgctt tctaatcccc taggatgaga tctgctcacc 73681 aagcaggaga ggagcaggca ttctgattgg actgaacctc ggacccccca tcagcttaca 73741 gaccgaggag ccaggcaaac ctggctgccc actgggctcc tttacctgtt tgctgtatga 73801 tcttgggcaa gccccctcac cgctctgtgc ccggcttttc cactgcaaga aaatggcaac 73861 aattatggta cctacctcaa agggtgaaat gaagcagagt gatgtgtgtc gggtgcccca 73921 gagagcacct acctgaggga ggctccaaag ctagcaagag gcagcaggac agggaccagg 73981 acgcaggctg ggtggagggc agtgggaggt ggtcggggct ccatctggcc ctctgagact 74041 taaaggagct ttgcttttca gagttgagaa tggagagaat gttacctctc ctgRctctgg 74101 ggctcttggc ggctgggttc tgccctgctg tcctctgcca ccctaacagc ccacttgacg 74161 aggagaatct gacccaggag aaccaagacc gagggacaca cgtggacctc ggattagcct 74221 ccgccaacgt ggacttcgct ttcagcctgt acaagcagtt agtcctgaag gcccctgata 74281 agaatgtcat cttctcccca ctgagcatct ccaccgcctt ggccttcctg tctctggggg 74341 cccataatac caccctgaca gagattctca aaggcctcaa gttcaacctc acggagactt 74401 ctgaggcaga aattcaccag agcttccagc acctcctgcg caccctcaat cagtccagcg 74461 atgagctgca gctgagtatg ggaaatgcca tgtttgtcaa agagcaactc agtctgctgg 74521 acaggttcac ggaggatgcc aagaggctgt atggctccga ggcctttgcc actgactttc 74581 aggactcagc tgcagctaag aagctcatca acgactacgt gaagaatgga actaggggga 74641 aaatcacaga tctgatcaag gaccttgact cgcagacaat gatggtcctg gtgaattaca 74701 tcttctttaa aggtgagtgt gcctggcttg gggttcagaa gaggtggatc tcagggccat

74761 ttctgtcctg actcaacaat ggtgttatta ggcaaaccac tgtagaggag agtgcccaca

74821 gcatgggggc agcataagca tcaaggcccc accctgccca taggcatcgc cgtctcctgt

74881 ggggtttttc caaattacag tttgtccttg gaagacataa ttcagtggag cccatcagcc

74941 tctggtctga gtcagtgtgg tgcttttcac tctgatttaa acttgtccgg caaacagaaa

75001 gaaggagctc tcctttcaaa ccactccagg gcgcRtagga gctagagctc cctccttgca

75061 ggggtgctgc tagactaggc caggaagtcc ctctgtctgg atgcacctgg ggctcctgcc

75121 ctgcacatgt gggaggagca cattccagcc aggggccttg' gtgtctggag gtggccaggt

75181 ggggctgggg ccatcttcac agggcaagat aatccccaag gagcctggcc acttccaaga

75241 ttctatgatt ctactctgct atcatcttta attattttaa aaaatatgtc actgacacat

75301 aacaaatgag ggcagaaatg gcattgttcc catctgggga agagcctcaa gggtgggcag

75361 tatacaaaac atgacccttt gccagattct aactggtcca gtgcccaatc ccattgatag

75421 aaactcaacc aatgcaaacc tcagcctgca agctccgaag gggcagagtg caagccggta

75481 gcttttgcct cctggagccc aYagtccaga tggggacaaa aaaagagata gggacacaaa

75541 gagtgatcac tgagccagag ggtggaaagg tgcttaggag acatgagctg cttggaggca

75601 gagtcctgct tggaagctgt tggttgattc ctgggcaagc cacttcccct cctgggcctg

75661 ggttttcatc tgtaaatgaa ggcgtggatc cagatctccc tctaagacta ctccaYgcct

75721 cacgtgccat ttgttctctg agtttcccat gttctcgcct cctactacct agccctatgc

75781 taggactctc ccctccagga cacagtagcc agcctagctt tcccctcccc acctgcctct

75841 aacaatggga aacaggcagg tggtaaacag gtgggcagtg gaggtggccc catgtctcca

75901 gcctcccctg gaagctccca cccccctcat tgttcagtgc tctggtcctc ctggagtgga

75961 gacctgcagg gcccctcccc ttcctctgtt gacctctcct cactctccag gtgccagttt

76021 tgctccctgc ctcagcctgg tttacataca gtgtatgtga cggggcttgg tcactgctgg

76081 ggcagccctg tggaaggtgg aggggaccga gcatgcatga gcttcaggct gagacagtcc

76141 cagctcagaa ccctggagtg cttgttccct ccctttctgc tcttcctctt ccattgcacc

76201 cactggaccc aagagcatgc aaggattgac tcacccagtg atgctagaac tatgtattca

76261 gctgaaagta agggggtggg ggcatccaac caggggcaga agatgggaat tcaagaaagg

76321 aaggtttccc ctagaaaacg gttttcgtct tttctcttaa atccagatag aataagaagc

76381 gaaggccgtt acagcagaga gaaagtYgag tcaagcagag atcagatact aaagacacta

76441 gactaaccag acattcgggc cctcagttga acagctgagg atgtcagaag atgttaagga

76501 ggcaaaattg gaaaacttgg tggctggcag acagaaatgg ggggagatgg gagcagatgt

76561 gagaagattt aaaggcttgt agagcttggg tggtgatttc atccaccaaa cctatctctc

76621 tccccattct ggcatacaag gcagcagtca gggtccccag aggcagcccR tctttctggc

76681 agggacccat gctggagatc tggccagctg aaaggcccca aaggagctcg gtgccctggg

76741 taatatggga aggtgctcca tggcactgcc ctcacatgga ggccacagaa gcccctgaat

76801 ggctgctgca attggtaacg gggacacctg ttcaactgaa atatctccta ccctgagatg

76861 ggtcctttct ccaagggatc tttacaatta catttgtccc cagtcattcc atgttgggag

76921 gctgcaggga ccagagaagc tgagatggtc tttggggagg ggaaaggaaa gatggacagt¹

76981 tattttggtc ctagaaagcc caaaggtggg gaagtgtcaa gaaggaagat gagggcacaa

77041 gagaatgtag ggccacccag aagctggctc tcattgcaat tacagaaaga aaaaccaaaa

77101 taaagaaaga aaggaaagaa gctcccattt attgagcagc tactctcacc agccattcac

77161 atgcaatacc tcgtttaatt ctcgcagcgg ctctgaaagg tggatggtgg tattgccatt

77221 tgttaggtag gagacatgcc gtccagaaaa gcaaataatt aaacattcaa agttgacctg

77281 ggcccatttg aaaattcctt ttgctccctc attttaaccc ctaaagtaaa gccgtttgtg

77341 actttatgag cttttaccaa gcatctccta aaaccaagaa tggaggtgaa agattgtgga

77401 gcccacaacc tagagaaagg attgacaatt ttttttccat aaagggccta gtagtatgta

77461 ttttaggctg tgtggtccac atgagggcag attcttcttt ttgacttcct cctctgcatc

77521 ttcttcatct tctctttcct cttcat.tttt tttacaacct ttgaaaaata taagcaccat

77581 tcttagcttt aggtacacac aaaaataagc tatggctgta ttggcttaca ggctatagtt

77641 tcctgacccc tgttctaggg gaggaaaata attgtaccca actaaatgcg tgcgaatcat

77701 gggcctatgt catgattccc aaagaatgag tttcatggaa ttttcaacat tttaaatatt

77761 ttactccatt cttcccttgc ttgcatagtt tctgatgaga agtctgctgt cattttcatc

77821 cttattcctt tttagataag gtggagtttt cctccctctg cctctacctc tacctctttc

77881 aagattttct ctttctcttt actatggtaa ataggccttt agtgagagga gttatgtcag

77941 cctggctagg agtcaggctg catttcaggt ttgtgatagc tagaggtacc agaggcagtt

78001 tcatggaatt ttacctttgc aacactgaga gcctaggcag cctcagagtc agaacaccca

78061 cagttgaatc ctcagcctga cagacactga atccagggca aatcttagct gaatattcat

78121 ggtctgtaga ggtggacatg agctagatat gagctaagga ccatagccag ctcatggctt

78181 ttgtgatgtc caacaccgct atcctctaag atgtcacaag tgtccctagg cttttattcc

78241 catggtctct cctggctctg agttctatct tccattaagg ttcttcctgt tcctcccctc

78301 attcacactg attggcatct cttctgtctg ccctcaccaa ctcacataca gaacccagtc

78361 tctttcctct tatttccacc caaagccctc ccacaagcca ctgttatatg ttcacatccc

78421 tgtaatacca gtgagtaata attgctaatg agacattttt ccttttatgg aacaaaggct

78481 gtcccatttc tcctcaggca ccagcctccc acatgttgtc atgcctcttt cccccacttt

78541 ccctaaacct tctttctctc ttgcactcct tattccctgg ttdctattga tttctcattt

78601 agcacaagga actaggtctt tcttttgtgg cccttttccc aatccaagcc tgctgggctc 78661 tccctcaccc ccaataactt ttactcttgc caagctactt ctctaaacca aagcagggtc

78721 cctcctatga gggactctgg gcacttccac tgctgcggaa gcagggtcga gcagggcgac

78781 ccttgcactc acaccttctc caactgcttg ctccaccttc agccaaatgg gagatgccct

78841 ttgaccccca agatactcat cagtcaaggt tctacttgag caagaaaaag tgggtaatgg

78901 tgcccatgat gagtttgcat cacctgacta taScttactt ccgggacgag gagctgtcct

78961 gcaccgtggt ggagctgaag tacacaggca atgccagcgc actcttcatc ctccctgatc

79021 aagacaagat ggaggaagtg gaagccatgc tgctcccaga gaccctgaag cggtggagag

79081 actctctgga gttcaggtga ttcttcctgg cccccaaaga ccccacatct ctccacgtca

79141 aggtctcacc aatgtccagg gacaagggca tggtggtggg agaactcata cagggacagg

79201 tggaatttac acttactttg ccctatgctg cctacatggc tttgggcttg atttttcttt

79261 ttcttcttta agacaatgac atcagacagg acaaggggct gaggcttcct ctgactccag

79321 catgttctaa gtcatgagaa atcttctgca cagtcccaaa cactcatgca tggtttctcc

79381 tggtctcaat ctcttgaagg gagagagaaa cagaaggaat tgtgatcagt tgagggctgc

79441 agtgagatgg actctgagaa tcagttctgc actggtgaac cactgtattt attcattctc

79501 tcagcatttg ctgcatgatt aattgagcac ctactatgtg tcagacacta atttgcaccc

79561 tgagagtaaa tcagcaaata aaacacaaga ttccctgccc tcctggagct taatttgtaa

79621 ttggagaggg gacaggcaat aaataaatat aacaaataag ttacgtgata tattagaagg

79681 tgagaaattg agtaagggga tagaaattga gtagaggagg atgaaaggat caggaaaact

79741 ggaactcgtg ttagtttgtg attttagata gagtagccat taggtgatgt ttgagcatcc

79801 atataacaga ggggaggggt ggagtcatgt tggtatatta gggaaaagca ttcctggcag

79861 agggaacagt cagtgcaagg cctctgaggt ggaagtgagc ttgatgtggt caaagaagag

79921 tcaggccaga gcagctgggc ttccacttcc tccatcttgt cttgatcagg gaggatgaag

79981 agtgcgctgg cattgcctgt gtacttcagc tccaccacgg tgcaggagca gagagagtga

80041 ggagagagtt gagagaggtc aggagtcccc aaaggggtgg agcagcttag gtagggccac

80101 gtagacccct agaaaacctt gcccttcctc ctgtgtgtga aatggagagc catcaggagg

80161 tttggaggag tgctgcgatc cgagtgttgt tttaaaagac taatcctggc tgctgagagg

80221 agaataactg tagagcaggt atggagtcag tgacacccgc aggaaccagg cacagacatg

80281 aggtgggagc ccactgtggc tgggatccag gagggagcca tgcatgtgag aagtcattga

80341 gttctggata aatctgaggg tagaggaact tgctgggaca cacggaattg agctgaccga

80401 tttcatgggg acacagtgag gaggagcagt agttccgggc ccagaccctg cagtgggccc

80461 agggagtgca tgtgggcagc tgtgtggggt agagaggaag gagcaccagc cttgggttca

80521 gaccgtggtg gctggtgtga cctggagcag gtcgctgctc ttctctggag ctcagctacc

80581 tcctgaagag aaaggaatgt cctttccccR ccacccctgt tttcactggg tgattgtgag

80641 aatccggtga ggtattgtat gttgaagcca taataaacca ctaagggcaa gggagctgct

80701 tcaacactaa cctgaggctg caacccctgc cccaaccact gtccagaagg ccggacacct

80761 ctcgggattg cctgaccctc agcccctcct cactctagat cccaggagac cccagaacgt

80821 gggggtccta cccaacccat ccgtttactc ccagactcct tcctccttta gcacctaata

80881 gccaccaggg agcaggggct cagcagataa ttttgagtgg aaagaattct ccaaacactt

80941 ttgatttaca aaatgctgag gaaacatgtg tccacacact cctggcccac agagaatgct

81001 caatagatac ttgttgaatg aaggatggaa tgaacggaca aacacatgaa tgaatgaata

81061 aaaatagaaa taggacacct tcctccttca Kgggactcag agtttaatgg aagacacagc

81121 ctcctgtata attgtaagac caggcagaca gtgacaRgca tcttaagagg gctataaact

81181 aagggagggg gagtttgcag gtggcRggtg tgacctgggc ctctaggagc ttgctacctg

81241 ctctatgcca gcccacacct ggcttgaggg acagtgccca ctggtgaggc aagatgggaa

81301 cctccaattg attgtttcag gatccccaaa gctcttctaa cacaatcaga ctcttcagag

81361 gcccccaggc cctttttgac ctgcctctgg ctcctggccc acctcatccc tcactaccct

81421 cctccctgaa acactgagat cacccaccgc cccgtggagc aactcctcct gctcccacct

81481 tcttccaggt tcttccacct gcctcctgcc cacctcttca cctagctagc .tcctttcctg

81541 cctttgggac tcagcctcaa caccacctcc tacaggaagc cctcctggtg cccccgtgaa

81601 gcaggctgcc atgcagccac tgcagctggc ccagcccagg ctctcaacac actcaggggt

81661 ccctgctggt gtgaaggtgc ttcaactgca ttgcaagctK cagggaaagg Rcagggccag

81721 gctcgagcag ggccacaact ccaggcttgg tgtgctgcct ggagactttc acacttgcag

81781 atctgaatga ataattaatg aataagaaga gtaaagacag gggttaagaa attgaggaac

81841 agattattta ttttccaatc agaagggggt gactgtagag gaaaccaggg aagaccatgc

81901 tgcgaggtgg gaggcaggta ggtactgatc agcagaggtt cagatacttt ttttttctcg

81961 ttttctagag agataggtga gctctacctg ccaaagtttt ccatctcgag ggactataac

82021 ctgaacgaca tacttctcca gctgggcatt gaggaagcct tcaccagcaa ggctgacctg

82081 tcagggatca cRggggccag gaacctagca gtctcccagg tgagtcttta gacttgggtc

82141 aattcatcct ttgtatccga acttgaattg gtgaaggcca gatggacttt tgggtactct

82201 tgaacttggg ttaatgcacg tgcatttctc attatatact caccctgctt gggacacccc

82261 caagccaaga agagctaggt tacagcccag ctcctcctgc cgtgttaggg gttgagcctc

82321 tacaacataa tgtcatccag gcttggaatc agagagccat ggacaccatt ccacactata

82381 ccatttacta tccatggggg caaacaatta aagtcctcca cccccagctt tccatgtgtc

82441 aaatggtagt gatagttctt ggctagtatc cagtgcctgg ctggacaggg aatgccaata

82501 ggtaataaca atgattatct ggcaattgta atgaaaatat gctcggagta tgagagaaga

82561 ctacttggga cactcagcct gtgttactaa aagcagaggc gccaaggcag ggtggccatg 82621 cagccttttg ctcttgtctg ccctctgtgc tcacacagca ctgggttgag gtctgcactc 82681 cacctttcaa acagcaaagt aagagagggt tgtgtgtaga ggagcagacc cgtatggttc 82741 aggaattcaa ggccatgaaa agtacttgaa agccccaagg atgtttaagc tagagcagga 82801 gagatgctga aagccatgct ggcttggctg aggaggtttc tgcagcagct gcttgtggtc 82861 aagagctgcc gggatgttgc ttagaagaaa aatgctttac attgttcttg ctcttcctcc 82921 caacagtagt ggctgttttg ggggcaaaat agactctcaa ctcagacaca aagggatgca 82981 tatgaggtgc tccattcttt acctcgatgg ctctgggcaa atcatactca gcatctgggt 83041 ctccatttgc acatctaggc atcaggactg tgcaaaacta gttggcaggg gagttgggag 83101 gagcaaacat tcaacagcac aaagacaggc cagcactagg tgctcaatgc acattag cc 83161 ccttagtggc acacaggcag gtcgctgaac tcctgcgcat ctgtgtttcc cgtgtgtaat 83221 gttctgctgt ccccacaggt ggtccataag gctgtgcttg atgtatttga ggagggcaca 83281 gaagcatctg ctgccacagc agtcaaaatc accctccttt ctgcattagt ggagacaagg 83341 accattgtgc gtttcaacag gcccttcctg atgatcattg tccctacaga cacccagaac 83401 atcttcttca tgagcaaagt caccaatccc aagcaagcct agagcttgcc atcaagcagt 83461 ggggctctca gtaaggaact tggaatgcaa gctggatgcc tgggtctctg ggcacagcct 83521 ggcccctgtg caccgagtgg ccatggcatg tgtggccctg tctgcttatc cttggaaggt 83581 gacagcgatt ccctgtgtag ctctcacatg cacaggggcc catggactYt tcagtctgga 83641 gggtcctggg cctcctgaca gcaataaata atttcgttgg aMacgttgct tgtgcctttc 83701 Yatgctgact atcagactct gcgcccctga ggctacctgt gccccaaaga caagcccctt 83761 gagctcccat gcaggctcag ctccaYccca agatctgggc tccttctgcc ttcagctgca 83821 gcagcctgcc caggactacc taagcttgtg gccaagctca cccagacctc aggcccaggg 83881 ttgggagggg accctgctgc tctaaggcca attcctgccc cccaggcttc tgggtgccca 83941 ctttcagttt ctctccttcc acccccaggg, cccaggctcc acctggctct ttccagagct 84001 cctagccctg accacatctg gcacagcccc cggactcctt gctcctgcag ctgtgcaggg 84061 ctttatcatg cgacatcctt cttctgccct ttagcacccc caatttgggg gaagtagcta 84121 ctttctgggt ttccagatgg agcccctcaa ctgcctcacc agttcctagc cctggctctg 84181 tgaatgatct ccctcaacaa ccagaatgca gggctgagga caaatgagcc atcagcgcac 84241 aactgcaata aagcaatcgt gtagtcaggc atttaaccga ggctcccagg caccttgcaa 84301 tctctatcac aaaggcaaca atgatactgt tgacaacagc tcagtacttg aggttttgat 84361 gccagacaac ctgccaagat ctctccctga aatagccaat tgaatcctcc tcacgtccct 84421 atgagataaa tgctctcagc agtcccattc tatggatgag gaaactgagg tgcagagagg 84481 cttagtaatt ttcccaaggc tacagagcta gtaattattg cctgtagaat gttatcccaa 84541 ccctcctgac accacaggcg ccctcttaac cacaaagtga tttccgtagg gattgccttc 84601 atggaacgta caacccgatg gcaaatagat ggtgaaacaa gtctgtggaa gctgagggag 84661 agcaccaaat tcagtttggg aagtcaggga aggcttcttg gaggaggcaa cttctgtgct 84721 gaggtcaggg aaagagaagg tggtcaagtg aacagagagg acaatgcttc agatgggaaa 84781 aagagcaatg gtagcattca agaaaccaaa agaagttggg tggctctggg gcaaagagca 84841 gagaggctga ggggctacag agaggaaggt gccatgacag agctggtggg ctgcagaagg 84901 gctggccgct ggcaaggatt cccaagtgat tccttagagc cacagggagc tctaagcgag 84961 tttaaacaca gaggtgatgg aagcagcttt acacactaga gaaggaccct ggctgctgag 85021 tagaaaagtg attcatagcc caggacaagg atgtgggttg gacatcgagg gggctctgtg 85081 ggaactgggg caaaataggt cagagctggg gagggagagc gggatgattc tgttggaagg 85141 ctttgaggag aatgggtgtg aatttatgat tgcaggtggg gtggaaggga gaataactat 85201 ttgggtttgg gtgcctgggt gatccccagt tctctgaata ggaaacccag cagggacttg 85261 ctggcaaggg aagtcgatac attcagattt gaacctccca tgtctgaggt tcctgggaga 85321 caccccaggg gtttgttcag gaagcagcta ggctgaggtc aggagagaaa tctgggctgg 85381 agggaagcat tcaggatcct cccctgggat gggcaagtga gtattgaggg tgtcccctca 85441 aatgagtgcc atggagtgaa aagaaaaggg aaacctcaat gactggctaa gaaagggcag 85501 cccaccgagg aaagtcacca gcgtggggca ggagacaaga ggacaggacg aaagctgtcg 85561 ccgcaggaac aagaggagat acttatccgg gggagagggg agaaaaccta gagacaaatg 85621 atgaatgaat ggaatgaatg ggtctgtggg atttagtgat ctaaaaccac tcggggatca 85681 caagtgcaat gttagcagaa ttaagggagg accacagtgg gctggagagt gagcaggaga 85741 gggagagagg gaaggcaaga cagcgtgtag ggaaaaaaga gatcagactg ttactgtgtc 85801 tatgtagaaa ggaaagacat aaaagactcc attttgaaaa agacctgtac tttgaacaat 85861 tgctttgctg agatgttgtt aatttgtagc tttgccccag ccactttgcc ccaaccttga 85921 gctcacaaaa acatgtgttg tatgaaatca aggtctaagg gatctagggc tgtgcaggat 85981 gtgtcttgtt aacaaaatgt ttacaggcag tgtgcttggt aaaagtcatc gccattctct 86041 agtctcaata aaccaggggc acaatgcact gcggaaagct gcagggacct ctgcccttga 86101 aagcagggta ttgtccaagg tttctcccca tgtgatagtc tgaaatatgg cctcatggga 86161 tgggaaagac ctgaccgtcc cccagcccga cacccgtaaa gggtctgtgc tgaggtggat 86221 tagtaaaaga ggaaggcctc ttgcagttga gatagaggaa ggccactgtc tcctgcctgc 86281 ccctgggaac tgaatgtctc ggtataaaac ctgattgtac atttgttcaa ttctgagata 86341 ggacaaaaac cgccctatgg tgggaggcga gacatgtttg cagcaatgct gccttgttat 86401 tctttactcc actgagatgt ttgggtggag agaaacataa atctggccta cgtgcacatc 86461 caggcatagt accttccctt aaacttaatt atgacRtaga ttcttttgct cacatgtttg 86521 ttgctgacct tctccttatt atcaccctgc cctcctacta cattcctttt tgctgaaata 86581 atgaagataa taatcaataa aaactgaggg aactcagtgc cggtgcaggt tcttggtgtg

86641 ctgagcaccg gtcccctggg cccactgttg tttctctata ctttgtctct gtgtcttatt

86701 tctctttccc ggtctctcgt cccacctgac tagaaatacc cataggtgtg gaggggcagg

86761 ccaccccttc acagtgtgca aatgcctatt tagagactgg cctttagggg aggtgagaga

86821 gagggtggtg ggtagtgagt gctaggctga agttagctgc agtgcttgac agatgtgaga

86881 gccttgaaca agctttcata accatagaaa ggattcagga ggcagggtga caagcaacca

86941 gggtcgcaga gtggcacaac tcctcaggtt acaattcaca ggtggtttga caccatccta

87001 agttacagtt cacaggtggt ttgacatcgc cttcaactcg gagttgcaga attagcagtt

87061 ggccaggctg catgaagcat ccctggaaag ggaacaggtg gagggctgga gggccaggat

87121 caaggatcaa ggattccact gtgatgggaa tgcaggcagg gcctggcgag ggggctggtg

87181 agggagtgtg tttcttggta ggatcaggtg ggacctcctc tcctccaatg actctgatga

87241 ttcctagtat aggaggcaaa gtcacctgct tagtgatatt tgccacaggt tggggcagga

87301 aaaggcacaa aatgggacac agagtgggcc acggtgtcac ggcagttcag ccaggctcac

87361 tgatgagcgc cttggagatc cagctgcagg aattcttggt ggttccaggc tttacagaca

87421 gttgtggaat cccccatctt gtggaatatt tctccattct taccagcccc tttgtgggct

87481 tcaagaaggc caactgctga tcagaaggac aggagtcaag ggggctggag gtacagacta

87541 cagaagggtt gacatcatgg acttgagacc agcactgggg ggtacagatg agggcagagg

87601 gagctgatca ctgaggaaga ctgaggatgg ggagatgggg tccctaggag gtccaagaat

87661 _/ gacctgttag aagtgccata tgaactacaa aggctacttt tcccccccaa agaggatttt

87721 ttcacattga ctctcagttt tctcaactgt aaagtggaaa ccatgacagt gtgtgcatgc

87781 ctgtgtcatc cgtgtgtaag aagtcagcaa gtcactgaaa tgcttgctcc tgagtctgaa

87841 cgttcccttg acagcaattt aaaaactcct gagatgatct tttccatgtg aactaactcc

87901 tcatccaggc tggcatggct tctcgtcact cagctggggc tggatggcat tgcactggac

87961 aaggctctga cctgcccacc tgcccagctc ctgcccccgg tccctcctga ccccagtcca 88021 ggtgtctaag gagccttacc acagcccagc attcattccc ttctgtgact taggtctgga 88081 aattgctggc tgaaaactga ■ gttcctccct taagggagcg tctgggcccc agatctgtga 88141 gggtggggct tagtttcatt cttccgcctc ccctgggggc tgagggccca tccacctgct 88201 ggtcactagc tattgccctt aaatggcttc ctgacgctag ctgcagggac aagacagcac 88261 ctgtcctgat ttactacctc cctcactaac caaaagtgaa gtccaagcct gagaggcact 88321^' gacaccaata aaagacacct acttactctc tcattcagcc cacgcaaatt gccaaccctc 88381 caaatgcagg ccctgagctg gccctggaga ttccgaggtt aagaaagtgg acctggaatt 88441 tgccctcata gaatgttcaa tttgttgagc aagacagaaa actgagcatg gatgtgacag 88501 cagccctcgg gagtggggta cgtgatgccc agagagggca ggaataaacc ccagactaga 88561 agagtcaagt ttggtctcct agaagagctg tcctcaaatg caaaatccag tacagtgaag 88621 aggagacacc agggagatgt accagcagaa aaggagaggg agtgcagtgt gtccatggag 88681 ctagaagaag atcctatgtt ctggataact gatgtttgag ggaaccatgg tcatctgtgg 88741 agctaaagag aaaaacatga acaagaccat gctttgtaaa tcatgttaag gatctcagag 88801 tttattcaaa gagtgatgag ccacagtgaa tattatacac agggagctgt tttgattaag 88861 tttcattaga aagatcaccg tggctgagca gggaaggatg gatacagtat tgagtgtgga 88921 tttggtgaaa agaagagaag cagaatgacc aagaggttca gccttagcta ggaattggga

88981 gaggacagag aggaaaggag actaattgga gagatattta ttagacagaa ttgatgagac 89041 ttcatggttg attgtgtggg ggacagaaag gaagcaaagt tgctgggtcg ggaacttggg 89101 gaactgaaat ccacatgcca ttctatgagc taagcattac agaatgaata acgttttgtg 89161 caggaagcag ataagtcctc atgtgggcat gtggagttgg agatgtctgt aggccatcta 89221 agaagagaag tccaatagag aatgggctct atggatctga acttcaatag ggaaatttgg 89281 gcaggaggga tggatttcag gatttcttct tgtcaaaaat gtgaggacac ccctggcaaa 89341 tgacttctat ttttccctgt gccatacaaa gagatgttat ctgctgagtc caccatgggg 89401 aagcataaaa cccagaagtc tggaggaggg gagacgagga cacWtcagga aacctcgatg 89461 ttctagcagt cactaataag ggtcccttgg gggctggaga ctactgtgtc actagcctgt 89521 acagttgtgt ggttctaggt atactMggta gttcagacat agacaaaaag gggatagact 89581 gcaagtggct actggagcca aagtttcccc tggctacagg acggagggac catcagtggc 89641 tgacacaagg aaaaataaat atatctgaaa atattgacca gagagtcatt caaatgatgg 89701 gattttcata ttccaggctg gggacatcaa ggagccataa caagaggagc tgatgggtga 89761 tagaggtgtc tggaaacaag atRgtaattt gaagttgaat agagcatggt gcattgaggt 89821 tgaagacatg ggaggattca tatattgcta aaaggcttcc ttccacttgc tcaacatcca 89881 ttttacacag atctaccagt tgggaaatgg ggaaacaatg cccacaaatt ccatgcagct 89941 ggttctcctg tttactcccc ctttcttctc agagcccttc ctcttgccac acagctcccc 90001 atagtgactt tcagtcagca aaccttcaag gtccagttca gatcttggtc acatgacttt 90061 agccaaatta cctggcatca ctgttactgc ctctgctctt gaatgatggg agagcgtcta 90121 ctctagagga ccatcaggtg gattacaaag aataataata acaagacacg tcaaagacct 90181 ggctgggttc cacaacccca gctccaccgc ccacagcctc tgccacacca gaaacatgca 90241 tgacgccctc ttgggcccac aggtgctgct tatggctgtg attgatgtgg iccaagaaggg 90301 cacagaggaa ttaagcttcc attctctaca aagaaaaccc tactgaccat 'tgtgcatttc 90361 aacagccctt tcctgatgac catcctctcc ccaggtaccc agagcatcct ctctggccaa 90421 aattgttgat cccaataaga aatgaaacaa aaatcacaac ttgcaaagca aactgaacca 90481 gtatgtgcaa aacaggtaaa ctatacccaa ccatgatttg ttacaggtac tgcctaggtc 90541 cagaatgtat tgagagcagc atgttcagac ccatgtgctc caaggcaagg ccacagcaaa 90601 tgcttctaag agtaattcca gacagactca tgggtttcat agataaaaac actgactact 90661 cgcttagttt acaaatcctg gccatgcttt cgaagtatca ctcagaaacc accatagagt 90721 aactcagccc atgagaccct gtatttccct taactaccct ctttcaagac tttactgagc 90781 tgccaagatg gtgttctccc ttgctcagag agtttaacaa acccagcttt gtttgagagg 90841 agtgaaacac tggcacacac tacaatgtgg atgaaccttg aaaacattat gctaagtgaa 90901 agaagccagg cacaaaggcc acatattgta tgattccatt tatgtaaaac atccagaaca 90961 ggtaaattca cagacactga aagcagatta gtggttgtcc. agggttaagg agtgaaagaa 91021 tagggatgac tactcaRtgg gtaaggaatc tcctttaagg gtgattacaa tagtttgaaa 91081 ccaaatggag gtaatggtta cacaacatat gaatgtacta aatgtcacca aattgaacac 91141 tttacaaagg ttaattttag gtaatgtgaa ttttgcctca attagagaga gagagagatt 91201 aaatgtcata tatagaagtt atttggattc taatggaaac aaatcaacaa taaaaaaaca 91261 attagggtca cagttacaca cctcttctgg cctggggata cactgaggat cagggtatct 91321 cagccgcagg ccaccttcag tgccacggga tgtagcgtgg ggcatcatga cccggttcat 91381 gcccaccggc ctggtttttc taccatctca gggagatatc tgcccctttg ggctgagaga 91441 ccccaacctt tccccaagat gaagttgcag ggtatcgagg taccagccag atgtcttctc 91501 acaaagggtc tgtggtggca taggaatggg gctcctgcca gtaacaggga aactgacatg 91561 gtggaactgg ctgaactctg aattgtgacc cctgctacaa gagaagggca aatgggtaat 91621 caccaaccca aacaaagctg aagaagagca aacatgccca gtgccccagg aagaagagga 91681 ggaggtgtgg gtactgacac ttcccctgca agcccaccac accatggaga agatggagga 91741 gtttgtgtac aaggtctgag tgggacagat gttggagggt catcccatat tgtcatggga 91801 tccttggggg gaaggggttg ctttgccagc cagaaacctc tgtggccagc agcacctaat 91861 gcctgagtat tgtttgtgtc tgctgggctc gttccatcca ctcaacccag caggctgcac 91921 tcagctcata ctatcagcct ggatcccaca cctgccaagg gcgagccagg agcagagtgg 91981 agaagggcat gtgagttagt gagtgcaggg tctggccgtt gcacacagcc aggcatgctg 92041 gctgctgtgg cagggcgggc agctctaggc actggcacag gtgctggctc catgcaaggc 92101 tgtggctgga ccagatgtac cacacgtggc ttctgttatg ggcacccaca tctggacaag 92161 gggaacatgg tggcacccag aagcttggag acatgaggaa ccaaagagcc ccaaagaggg 92221 tgtcacagcc ctgacttgga gagcccctag gtctgggctc cccaaaaggg atcagctatt 92281 ctctccttct tgttgcctac aacgtggcga gcagtgggaa gtgtttcagc tctgtgttac 92341 agctctttta gtccctccat ttggtgtgtc ccaagttctc atcctgcatc caggaagaat 92401 gaggtacatg gacaactgga gggtgagcaa ggcatggaag agcttcactg agcaacagaa 92461 cagctctcag gggacatgca gtgggtagct gctttccaca gacaggtgga aagatgtcct 92521 gacatctttt ggagtctggc tgagcccagg aattgtacag gttcagaagg gaggaagtgc 92581 atgcgaattg gtccatgggc ggtcataggc aggcccagaa aaagcaccat aagttctcac 92641 tctgtaccac ggaaccccac tcagaactgg cagcccagtc cccaggcttc agcctgtccc 92701 tggcttgaag gtggggcttc actggggatc caccactttc agcccagcaa actgtctgcc 92761 tcctgccatt aacatgctgt ccacagcact ccagctgttt gtgatgagag gtgtctgcag 92821 acccacctca agcctccctc agcatcccct tgacctccct cccgtgcttg ttggagctca 92881 aagtccggag ggtgctgagg cggcaggggg ctggcatgtc agcactgctc tgagtgtgca 92941 cacacccacc tggcttgtga cagcacctgg gctcggccac aactttgctc caccctggag 93001 cggacaccag gagtggaagc aggcacttta aagcctgttg gagcaagcag cttcctgggt 93061 ccccaagagc acagagatgc ctgggtctgg agttgaggat gggcggctgc agctgcacct 93121 gaatgcatgg gggtcccacc ccaccaattc agtaggggac agggctccct actgttacca 93181 gccccaactg gctccacaga gcatgcaacc ctggccaggc atttctcccg ccccgccccg 93241 cccccgtgct gctggcatcc cggcagccgc agctccagac aagctgctgc caccatcaat 93301 atgatgggct ccctgactgg ctgaaggaca atgactgtct gcaggacaat gactgtctgc 93361 tctatggcca tagacaaccc atgtcctcct tctgggcttg cttcaagagc atcttctata 93421 tccatacaga aaYcggcagc agccggacac atctgcttgg tttcgtgctg tttctctttt 93481 tggaaatctt gaccatgctc agaccaaata tgtacttcac ggcccctcta caggagaaag 93541 tgatttggag gatattcctt ttgggtgcag tgctctagcc tcagcttctc ctggctcgtc 93601 cgcactgtct actgtcattc agagaaagtc tctcggactt tttccaaact gtactattca 93661 gggattgctc cactgctcat aaggagcttc gtcccctggc tctgttactc cttctactgc 93721 tcgccacagc cacggctcat ctacttctcc atcatctatg tcctgggcat ctctgccatc 93781 attgtgacag tgggaccggt ttgtcactcc taagcaccgg cagacaaggg caggggtgtt 93841 gctgggactt ggcttgagcg gtattgtgcc caccatgcac tttcctattg ctgagggttt 93901 cgtcaaggcc accacagtgg gccagatggg ctggttcttc ctcgtggctg tgatgtacat 93961 caccagagct ggcctttatg ctgcttaaat tcctgagcgc ttctttcctg gaaaattaga 94021 catatggttc cagtctcagc agattttcca tgtcctcatg gtgacggtgg cctttgtcca 94081 cttctgtggg gtctccaacc ttcaggaatt ccattacagc cgagaaggtg actgcactga 94141 tgactccctt ctctgagcct tcccatctga ggggtggagg aggaacttcc caagtgcttt 94201 tattttattt ttatatttat agtttttgag acagagtctc tctctatcac ccaggctgga 94261 ctgaggtggt gccatctcag ctcactgcaa cctctgcatc ctgggttcaa gcaattctgc 94321 ctcagcatcc tgagtagctg agaccacagg cgtgcaccac cacactcagc taatttttgt 94381 atttttacta gagatggggt ttcaccatgt tggccaaggt ggtctcaaat tcctgacctc 94441 aagtgatcta cccaccttgg cctgccaaag tgctgggatt ataggcatga gccactgtgc 94501 ccagcccagg tgctttttaa aaataacttc ttcactgaag tgagaggagg agtctgagtt 94561 gtctgtttct agaagaaact cttagagatt tcagtaccaa ccaagcttca gcccactttc 94621 acacccactg ggcRatacac tttccatttc cactctccta gctgaggatg gggcatggtg 94681 aaacttagcc atcccctcct cggcagtcgc tctctttggc aaagcaacta ccagtcccca 94741 cagagacagt actttgaacc tcatgttgag attttacccc aaccattttg ggaaaattat 94801 agagtggaac tcttgagaaa tttgcttttt ttcttgaaga aaatgtccct cccttaccct 94861 catccttact ttgtatcctg gcttatacca ggccatccat ttttgtagca cacttttcaa 94921 aagcaattgt ataacctgat cccatctttc tagggcctga atctgcttac atagcaggaa 94981 aaataaagcc tccaactctt acacaaccca gataatcacg gaagtgtgtc caggcttgaa 95041 gtaacttgag ttttaattat ttttttcttg gcagagtaat gtgaaattta aatggggaaa 95101 gatatttaat atttaatact aagctttaaa aagaaatctg ctatcatggc tatgtatctt 95161 gatgcaaaga ctgtgatgtt aataaaagaa agtacagaat acacttggca ttcaaagaaa 95221 aaaatgatta ggaatcagtt aatggcttga taacattaag aaattattgt ttttaaaagt 95281 gtgacatgct attacaatta cgatattttc ccaattttta cacataaaat gaaatatttt 95341 ataggagttg ctttgaaata ttccacagga agaaagagat tgggaggtat caaaaaatga 95401 tattggtctt atattgaaaa taactaaagc tgctggtggg tatatagggg tgcattatac 95461 cattctctct atttttgtgt atgtttgcat ttttccataa caaaaaaaaa atcctccaga 95521 aatcccactc ttgggtatct acccagagga aaagaagtca ttatacaaaa aagatacttg 95581 cacacatgtt tatagcagca caattagcaa ctgcaaaaat atggaaccag ccaaaatgcc 95641 catcagtcaa ggagtggata aagaaactgg ggtatatata tactgtggaa tactactcag 95701 ccgtaaaagg aacaaaataa tggcattcac agcaattgga ggccatcatt ctaagtgaaa 95761 taattcggga atggaaaccc aaacgttgta tgttctcact tataaatgga agctaagctg 95821 tgaggacaca aaggcacaag aatgatacaa tggactttgg ggacttgggg gaaagggcgg 95881 gaggtgggtg aggtataaaa gactacaaat agcgtgcagc gtacactgct tgggtgatgg 95941 gtgcacccaa atctcagaaa tcaccactaa agaacttatt catgtaacca aacaccacct 96001 gttccaccaa aacctattga aatataaata agtaaataag taaataaata aataaataac 96061 attagattgt ggtgatggtt atataatttt gtcaatatac taaaaatatt gaatggcaca 96121 ctttgagtgg gtgaaatgta taatatataa attatatctc aataaagcca ttaaaataaa 96181 aaMaaatcct tgagggcagg attgttcctt attccccagt atttaatgca tcatcctcag 96241 atgcagtaag cattccataa tgaatgaatg aattagtgaa tgaatgaata caatgaatct 96301 cataatacac ccctgctgtg ccatccctga tgtgaacatc aagaattgaa ggttttagga 96361 agtcaacaag aggtgactgt gtggctattg atgtcaagac

Following is a SERPINA5 genomic nucleotide sequence that includes the SERPINA5 SNP "SERPINA5-AA" (SEQ ID NO: ).

TCTCAGGAGTGCCCATGCCATTCCAGGAAAATGATGGCCCAGCTGGTGG[T/C]GTAAGGCTTGGGGGGCAGCGAGTGGGC ATCGTGGTGAAAGCCTCGGGATCAGGGAGCTGCGTCTGCAGGCAGGCCTGCTGGCCGGAAACCTGCCAGGAAAGGAAGGGG CTGTCCCGGGGCGGGGCCAGGGAGGGGTGGAGACAGGGCCGGCTGTGGTCAGTGACAAATGCTGGCTGCAATCCAGCCAGC CCTCTGCCCTTT

Following is a SERPINA5 genomic nucleotide sequence that includes the SERPINA5 SNP "SERPINA5-AB" (SEQ ID NO: ).

TCTCAGGAGTGCCCATGCCATTCCAGGAAAATGATGGCCCAGCTGGTGGTGTAAGGCTTGGGGGGCAGCGAGTGGGCATCG TGGT[G/C]AAAGCCTCGGGATCAGGGAGCTGCGTCTGCAGGCAGGCCTGCTGGCCGGAAACCTGCCAGGAAAGGAAGGGG CTGTCCCGGGGCGGGGCCAGGGAGGGGTGGAGACAGGGCCGGCTGTGGTCAGTGACAAATGCTGGCTGCAATCCAGCCAGC CCTCTGCCCTTT

Following is a SERPINA5 genomic nucleotide sequence that includes the SERP1NA5 SNP "SERPINA5-AC" (SEQ ID NO: ).

CTAATCACAAGAAAATGACAGCCCAATCCCAAGTTCCAGGGACATTTGGCAAAATAGCCCACCACTCCTACTTAAAAGTGT CGAGGTCTTGAAAGGCAAG[A/G]AAACCCTGGGAAATCGTCTTTGGCCGGAGGAAACTCAGCAGACATGACGACTAAATG CAATGTAGAATCCTCGGACAGAAAAGGACATTAGTGGGACAGC [0311] Following is a LOCI 15209 genomic nucleotide sequence (SEQ ID NO: 5).

MPRP-l REGION GENOMIC >1: 58292101-58392200

1 tgtggcaatg gaggagtgtg aggactaggg aaggctgagt gaggacggca gaaggaagaa

61 aggatcagcg gggatttgta tttgccaagc ctgtggctgg tttttggcat gtgtaactta

121 gggccagaaa gcaaggtttg cagaaagatg atgacacaaa tctcgaaaat atccattgag

181 tcaccaaata cttatgaagc tccagctaca tataagctcc accacctcYa attaRgcctt

241 aagtatggct cagaaatacc taaggagctt gctgttaaaa tcctagcact cagaccttac

301 tatagacaag tcagtatctc tggaggtgaa gctatgggca ttggtatttt ttaaaaacat

361 tccaggtgat tttaatatgc atgcagggtt gagacccccg gaattcatta tctcatttaa

421 ttcttacagc atccctgtaa ggttctatta ttattatctc agaaagacta agaaaccgct

481 cagaaggagc agagccaggg tttaaacttt agtctatgtg cccgcaaaat ccatcctttc

541 tgccagtatg caagcttata acttaaagga gtcttaaagt ttgccctgtt ccatctcctc

601 tcattttgca cagtagaaaa tcgaggtctc aggattggaa gtgaactgtc agaggtcact

661 cataccagtc atgtcagagt ccagactcca acctgcctct cctggccctc agcccagaat

721 tcattcttcc cagccaggct gcattctgtt ttagtctaga atattgatcc aagaagtagc

781 gaggaaaacc acccgagagt cagacagtgc tccctccctc ccaaggctgg aaagacaggc

841 acggtatttc ggggaggtag tgagaaaaag agtcccagct ggccacctcc tcatgtctac

901 acaatagctc cagctcagt'g acagccaaac cccttattaa gcggcctgtg ccatctcacc

961 tcctgccctt gctgaactta cacagctca't gttgtacaga ttagggaaaa aaatccctta

1021 accccgaggc agagcaataa caacatggaa gccaacacgg aaggcagttc gttgtgttgg

1081 cttgaaaaat aacgaaggtg acatttaggg ctgctctggc ctccctgtca tggagtctca

1141 tcattaatta aaccgtctct gttacagaca aacttcctag tcagtcttgg agtgggggtg

1201 agggcttcct gtcctctgtg gcccattaaa gatgtaggag tcttctttta tttccctctg

1261 tccccccagt cacctgaaat ctagtctctg tccaattcct ggtgctcaca tgacatttct

1321 tcaggagaRc ataattggct gttgttgacg gggaaaggtg gggagaaaag gcaagaatgg

1381 tccgctacac atcaacgctc tgcctggctg atagatgcta tttattgaaa gcccatgatg

1441 gaccactcac tcattcatac attaattcat tcaacaatta gttacaagta actcatttat

1501 gtcaggcact gtactaagtg ctgaatatgc catttgatcc aaacaggcat gtcccctgtc

1561 ttcccggagc acagagtcta gtgctgccca acacagtggt cacaagattc aggtggcttc

1621 ttaaattcaa attggtttaa attacatata attaaaaatt cagtttctca tttatactag

1681 ccacatttca aatgctcaat agccacatgt ggctagtggc tgccatatca gaccgacaga

1741 acagtcccat tgtcacagaa agttctacca gacagcactg gtctagtgag acaggcagac

1801 actttctata tattcttgcc tctacccctc aaagatcctt tggagatagg tgttgtttcc

1861 ccattttaga gaggtggaaa cagtgatcag ctggtcaatt tggagccagg atttgaatcc

1921 aggtttgttc tactccaaaa tctgtaagta actaaaaggt accagtatca aagctacagg

1981 tagcaaagtg gttaaaagaa tatgttttgc aggctgggta cagtggctca tgcctgtaat

2041 cccagcattt tgggaggcca aggcgggtgg atcacttgtg cttaggagtt cgagaccagc

2101 ctggccaaca tggcaagacc ccttctgtac taaaactaca aaaattagct gggcatggtg

2161 gtgcatgcct gttatcccag ctacttgaga ggctaagtca ggagaatcgc ttgaacccag

2221 gaggtggagg ttgcagtgaa ctgagattga gctgagattg tgccactgta ctccagcctg

2281 ggtgacagac aaagattctg tctcaaacaa acaaacaaac aaaaaaaaaa aacggtttgc

2341 agtctactta ccaaagtcta aatattaatg tggctcaggt ttttttaacc tctctgagcc

2401 tcagtttcct cattatataa ggatattcat atggtcactt gatattaagg tagagatgag

2461 tggtgagata atatatgtgt gcatgatgcc tggaatggag aaagtcctta atgcatggta

2521 gctgttgttt tggataagaa agctgagtgt aagataggag aatgaacaat agcagcttag

2581 gaccagaaca ggattagccc agaaatcatt tctttggaaa agttaagaag acaaaaatta

2641 aaaccgccaa agaacacaga gagtgggctc aggattttga gcattgcgtt atctactgca

2701 atgttacaaa atcaccaaaa cctaggatct taaaacaata aacatgaatt atctcactgt

2761 ttccgaggtt cagaaattgg ggaacagctt agctgggtag ccctggctca ggatctcttg

2821 caaggttgca aaataactgt tggcttgggc tgtgtaatct gaaagcttga ctggggcagg

2881 ataatcaact tgcaagagaa tttagtgatc aggctgttgg caggaggcct tggtttctct

2941 tgggctgttg gtaatcatcc tggatcttta ccacatgggc gtctacacaa ggctctccaa

3001 gtactcttaa gaatggcaac tggcctttcc aagggcaaga ggcccaaagg agaaagaaag

3061 aaaaagagaR ggaacaaaaa taagagtgca gagagagaag gagcatccag tctttttata

3121 atgtaatttc acaaataaca tactatcatt aatactttat tctatttatt agaaacaagt

3181 cacagggccg ggtatggtgg ctcacaccta taatcccagc actttgggaa gccaaggtgg

3241 atggatcact tgaggccaag ggttcaaaac cagcctggcc aacatggcaa aaccccatct

3301 ctactaaaaa tacaaaaatt agcctggctt gatggtgcat gcctgtaatc ccagctactc

3361 aggagactgc ggcatgagga tcacttgaat gcaggatcca gaggtagcag tgagctgaga

3421 tcatgccact gcactccagc tgggtggcag agtgtgactc tgtctcaaaa aaagaaaaag

3481 aagaaaatca caaagtccag tccaacctgg actaagagag gatttatact ccacatcttg

3541 aaaggaagag tactgaagaa tttgtggaca tatgttgaaa ccaccataaa catgaactgg

3601 gctaagtgcc cagagctccc tttgagcaga gagcatggat gactccacaa gagttgaagc

3661 acaaagtcta ggcatatata tataccattt tactatccag gagctctggg tcagacccag 3721 agggtattaa gatgcctgat cctatcagat gaggaaaatg gcaccagtag gacatatctg

3781 tggtagagat gcacacacgt gggactgggc agggaaggag ggtgcattat ctgtatttca

3841 ataggatatg acactcagta cccatacaac ctttcttcta attggggtgt tgtgtttgga

3901 gaggtgggga ccagaaacac ttctacggag aaacatttcc aaaattgcat tgttttttat

3961 ttctggccag aacatctgtc ctgaattcct gtctcccttc cttcacttgg catYaggttg

4021 aatagtgaga aggagaagga agaaatgaat agttactgaa cacttactat gtcattttat

4081 ttatttctca taactgtctt atcagatagg tgtcacaggc agactattgg aaagagggtc

4141 ccttcccacg catgtgtgta gctgtccgta gtcctgaatc tcattgctct ctgactgggc

4201 tccacccaga cagtgtgtat aatgattcat gggagctaag gggaaaaaac atattggcct

4261 ttcaatttag atatttaaat ttaaaatcta tgaaggttta ctaagatgca atttacagat

4321 gaaaatgaat gctcagtatt tgtcacctac tgtttgtcag agatcctgga gaaagtgtaa

4381 gtgccccatg gtgcagagga gccacccatg acactctcac tccatgtttg gctttcaaca

4441 ttttatggtt gattagggat gacttgtgcc cagtcaagta gagttacaga ttatattatt

4501 taaaatacta gagctgagaa aagattatga aaRccttctg taccagatag agtttcactg

4561 gttatcccag tgggctgggt acttaaaaga gtcatcagtg taagcaagca tttttcttcc

4621 attagtaaat tattttaaat tactatttat ttttatctca tgcttttaaa aacctccatc

4681 ttaaaaatgt ccacttatgt atgttttaga aataaaatat tagtacagaa gttaactgtg

4741 tactgtgtta atatagaaat atatatacat tggtactaga agctcaaaat ttttattgcc

4801 agtagaggaa tatgatcaaa aaagagtgaa gactactgtc ttagagtcta gttctttctt

4861 Wtaatgtgat tgaaacttgc tctcattctt ttggagcaat taaaagtaag gaaaaggcag

4921 gggtagctag aagggaaaaa gcaaagatgg agacacagaa gagatgaagg ctttggcggg

4981 ccagtgctac tcagggatgg cccaagagaa agcaagagaa aaatctgtcc aaagctgttt

5041 tcacataatc acattaaccM aggacaaaac cacagtcaac cccagctaac ctactaagca

5101 gctaaaaaag ggtcagaaag gtacatacac atcaaaggat atggagccag caagtgtgga

5161 gatgaacaat ggtggttcta cgagcacccc aaagactacc gatgaaggca ctgaactctc

5221 tctgaggctg aattattccc aatggctcct gattttttct gtttttattt tctatcctga

5281 tgagaaatgc gctgattttc accctgtctc agaacWaata gaactttgag atgtagttca

5341 caatttatgt aactgatttc atatacttct gccagctata tcatgtttct gacaattaca

5401 aatatttctc tcctcacacc aaggaattgt ggggcatcca caatcatgct gctctccctt

5461 gtatgctaca gtctgggtgc tattccatct gacactgcag gcaaacaaac tgaggctgac

5521 aggggtgatg ttacttaccc aaggactcag gggggtaatt ggcagagaca agattgagat

5581 ccacgtcgat ctgagaaggt ttcttttttt tttttttttt tttttttgag acggagtctc

5641 gctctgtcgc ccaggccgga ctgcggactg cagtggcgca gtctcggctc actgcaagct

5701 ccgcttcccg ggttcacgcc attctcctgc ctcagcctcc cgagcagctg ggactacagg

5761 cgcccgccac cgcgcccggc taattttttg tatttttagt agagacgggg tttcaccttg

5821 ttagccagga tggtctcgat ctcctgacct catgatccac ccgcctcggc ctcccaaaga

5881 aggtttctta actaaattct tttctgtatt ctaggtgtta gtctggatac cctcaatccc

5941 aaggcatctc aaccagtagc aatttttagc ggttcagggt atccccaagc tgttctcaaa

6001 acttcaagtc tcattaaaat ggcacaatac aggtgatttt ttaatgagta cagtgttttt

6061 attggatgaa atctttcaag ggtggagtta atgatgtaag aaaatcagat atgtggtcat

6121 cggtggtcag aatatgggga gccattgctt tagattttca cccagaagac aaatatcccg

6181 cattaaatcc ctttaacttc aatagcatac aacttagcca gacttcttat taagcaggta

6241 acctcaggct gttcatttga ccttatgtgc ttcagtttcc tcctctgtaa aatagggatg

6301 aagacagaca tacctctgag tgttattgta cggattgaaa gaactgaaac atgtacagaa

6361 cttaaaacag tgcctgacac atagtaggaa ttcagggaca actgtcgttc ttattgttat

6421 aacctcagct tccttgtctg taaaatgggg gtagtttatg tactatttat ctcataggat

6481 gattgtaaga ctcaaatgaa atggtgaaaa agtgcttcat aagcaatgtc atactctgaa

6541 gatgagaaag tatgctgcaa ttttcactcc tatgtctcac atacgaaaca agtctaagaa

6601 cagtgtattc cagccaagaa attaaaagct ttgttccttt ggagtcaaga gtgtgtccct

6661 gcacagatca atgttgctga agtgaaaaga gagagattta attacgttga gccttagtgc

6721 cttccccact gagagcagag agctcctggt gagaggagta gctgagtgtg gaggtgacag

6781 gtcgtcgtat gagtgcctgg ggactcctag acataagctc tgtcaccttc ctagggccag

6841 acaacttgac aagggaagag ctggctccaa ggagaaggtg tgaacctgtg tctttgaaag

6901 gccatgatct gtgatgaaat ctgttttgtg tgtggcaccc tggggagaag gaggctaagg

6961 ctgccttcct ggcccttgca tggcWgtgtg taaatcttca tgttcaaggc atatggtgtt

7021 tgcatacact ggtatccaca tcctaagggg tatgagcacc cacatactga gtctcatatg

7081 cataaggtca tatgcatgct tgagagtctg tgtgtacatg tatctacggc ctgggcacat

7141 cctgcatgca taaatgggtt tgcatgtgga tgctgcttct gcctccatgg gcaaaaatgt

7201 gcctcaatgt ctctgcactt ggcctggtgg acatttacag atgtggatgg ccatgtggac

7261 ccacctgtgt gagtccatgg catcacagat atatgaattc tgtacatgtc cttgtcatgt

7321 gtttcagtag agtttgagaa tctgagacag actgtggggt tgtccactgg gaccatctgt

7381 ggagctgggt ctccaagatt gtgggtgaat gccccaaagc taggaagaga taggaaggtt

7441 tgcatgagag aagStgagct cacagctcca agcaaatgga tcttgcatcc agccagagRg

7501 gtcaaggaag accagatact gaacgacagg aggtgcagag cctgggctgt aaggaggaca

7561 gttgaagagc agggaacggc acactgcaga aatgtggaag caaagtgctc tggccaccaa

7621 tccacaactg ccaagcaggc acaggcagaa tagcattttt gttgtttaat tagagatgtt 7681 ccgttaaagg tatcatacca gctataccat gtgtatgcat ggaagacatc aatgtgtgta

7741 ttgtcatgca tacactgagg tctgtatttg tacaggtcct tcccagggct tgacatatgc

7801 ccagggcatg tcaaggattt ccactgttac tcagacagca tttagacagc actaactgtg

7861 tgcatgatat gtttgggaga ggatggaatg aagtgggatc gtgtcccctg tccttgaggt

7921 ttttatattc taaatggggc cagaaacaga gaaatatgca agcagagaaa aattataaag

7981 cagcataaat aagatgggta ggaattctac tgcctagact tgtgtttaag cctgaacttg

8041 gccttgtact agctgtgtgg ccttgtgaat gttatttaac ttctctgagt tccttttccc

8101 tcatctatcg gatatagcat caatataaca caaagatata gcactaggtt gctgtgagaa

8161 ttaaaggaag taatatatca aaggcaccta ataaaatata aagtacaaag caaatacgat

8221 ggatgtgggc ttgctcaggc aggcttcttg gaggaggaga cRagaactga acagggtgat

8281 gggcaaggct aaccctagcc caggagagga tgcgaccatt ctaaactcca tatcaggcag

8341 cccttgccct cacacctcag cagtatccaa acaccaggct tcctctaatc actgaatatc

8401 ggggcaggag aggaccttag aaacatgaac ctaacccatc atgttgctaa ggcagaaaca

8461 gactcagaag agctcatcaa agcctttcca gaagtttgca ggagtagctg acacagtgtg

8521 aggcactgtg ctggtgcttc tgcacacatt ctcagcctgg gttattggct gagttgctgt

8581 taaccaatac agtatcttta tcaaataaga aaagtactct cctctggaca ggtgcagtcc

8641 atcagagact cgcatgacaa gctgtaagca atgttgtgtg aatgcaaact agaacactgc

8701 ctcattcagg caggtacagc ccctgagcac accactggcc accaagccac aaggtggact

8761 gcagtMcccc tctcctctca ggcaaacgcc ctgcatgacc ctagagagtg gctgaccctg

8821 ggtttgagcc tggctagggc aggggtcagc caacatgtag gcactgatga tgtggcagga

8881 aacaggacat cgtcctcacc cccgcaggaa ttctcagttt attgcaagaa atgacaacaa

8941 caacgacgac aaaatgtgca accaatcact gtaaaaagtt ctgtgggaaa aggaggctac

9001 aggctcagag gaggacccca aaccaagcct cagggtMagg agcagcttcg tggaaagatg

9061 gtgaagRatt taggacacag tgaggtgtag gtatatttgg cacacagcag cggtgggagt

9121 gcMcagcttt tacattttga tgcagcccca tcaaaccaat gcattgaaat ggcccctaaa

9181 tcaaaaatgg atccattaaa ataataatag ataccattta ttgggcactt accatgtgtt

9241 ttaattcatg tacttctgtc acaaccttag gagacaggaa ccgtcattat ccacacttac

9301 ccacgaggaa actggggggt tcagtgcctt gcctgcagta cccatggtca atggcagaaa

9361 tgggggctgc tgtgaagctg tgtccctcac cactacccga tgccaccttt tctcaggact

9421 gcttcccttg gcagatccca gggacagggg ctgaagcaga agccagatgt gcagggttac

9481 caaatctagg ggagtgtggt ggccatggag aatattcctc tcaRataccc agcttcaggg

9541 agcatgactg cccagcggtc cccacaactg ctttccaaaa tctagcacaa acgctgtgtc

9601 ctgactgccc ctggccaccc ccagccaatg gaggagcggg gcagggataa tgaggaaggg

9661 cccttcctgg agacRtggga ctcctctcgt gggcaacctt ggctccagga ctcccagaca

9721 gccttgccaa agtttccgta ggattgtcta aaacacttcc cccatccctc cctcccctcc

9781 cttgctcctt caccgggagt caggtctgca tcatggactt gtggcttttc cagcctcccc

9841 tggcctctac attttttccc acaggcattt cccctaacag atttcttgca tgtttaatcc

9901 tgtctcggtt tctgctttct cggagggcct gaactaacac agatggggtg ggtaggtctg

9961 tgtggaagca atgtgggggc ccaagggagg tccctgaagc caaggacttg gagcctggaa

10021 ggcagatgaa tgggatactc gggaagaatg cacaagcagc tgtcacggga agccctgaca

10081 ctctgctcat tcatcttcag gcctcagaga ggctgccgtY tcttgaaagg gacaatcctc

10141 cttccctgcc aaacaccctc ctgtcttccc tccacctacc ctcacctggt ctcatctgga

10201 ggtcattctt gcaggaagcc ttgacattct acacgggtga tgttttgcct ccttttacca

10261 ccacagcccg gttgaacagc gcctgtccca taactggtct gtgcaggggg agctgtgttt

10321 gtgcatctaa gcccccacta gttgggggac tccttgtggt gggtgtcagt ctgagccatt

10381 catcactgta tcctagtgcc tggtgcagta gtgcctggaa tgcaggtgtt gttgaatgaa

10441 tgaatatgtg aatacatgag tgagtggcct cacagcagat ctgcggcttg ccttgtgtga

10501 tgcagataca gtgcctggat gtagtgcctc ccaggggaca agtgggacca gagagtctga

10561 tatgaacctg accttgctaa tgagcaggtg ggtggctctg gccattctca aattcactga

10621 gccttagttt ccttatctgt gaaaagcagt gataatgccg aactccccaa gttgtgagga

10681 taacgccaaa ctctttgcct gaaacatgta acaaagtggc tgtcactgta acaggaactc

10741 aaacacatca ggccctgtgg cctggacccc agctgcccca ctgcagacct attgcccata

10801 tgtagcagcg ctcaaacaaa agcagaacgt ctgctttttt gattatattg aaaaaataat

10861 tacttaggct ttgccgtctg cactacctgc catctctctc cccagtcccc gttttctctt

10921 ctcctgatta ttaaaaacat aataaacata tattgctccc atgctactgt catagccact

10981 ggggattaag aaatgagtag atgagagtct tctttcttag agcttgtggt ccagtgaggg

11041 ttggggagag aaagagaata gaaacaaaca taaaaataaa taattgctac tYggtgcagt

11101 aaaagccaca atagattaag actcaactgc tggcatgtga caacatatat ccaaaatttc

11161 ccaaaacata gccaatttca aattatttta ttatttttca ctagaaacaa tttgttgggc

11221 atgatttaat atgttttaat tttttattat gaaatacttc aggcatataa aaagcgtagg

11281 tataatgaac aactgtgtac caaccacgca gcgtaaaata caaaacctgt ttgcattttt

11341 ctttttctcc ccagtggtaa cctctctcct gaatttgggt ttatctttca ttagtgtgtt

11401 tttggttttt ttgtttgttt gtttgtttgt tttgagatgg agtctctctc tgtgctcagg

11461 gtggagtgca atggcgcgat ctcagctcac tgMaacctct gcctccgggg ttcaagtgat

11521 tcttctgcct tagcctccca agtagctggt actgcaggca tgtgccacca cattcagctg

11581 atttttgtat ttttagtaga gacgggattt caccatgttg gccaggatgg tctcaatctc 11641 ttgacctcat gatccaccca ccttggcctc ccaaagtgct gggattacag gcgYgagcca 11701 ccgcacccRg cccttagtgt gtttttatgc ttttgYcaca tatgtactca tctacaaatt 11761 atatatgaca ttgtttcaca agttttaaaa ctttgtataa atgttacata ctgtatgtat 11821 cactctgcaa catttttgtt tttgctcaac attatctttt tgagatgtat gtatgttgat 11881 gcctatatct ctaattcgtt cattttgact gccctatagt attccattgc atgatgatat 11941 catagaattg atctgtttcc caggtgagag acRtgtgggc tgaaaaacag agtcactgtg 12001 tctttgcatt agcattcttc aggaagtaga caccaagatg ggattagctg tgcatgagat 12061 gtattggaga agctctggtg catgacaaag gagaggatca ggaggaggca gagagagcct 12121 tcagaccatg atgtgagtct gaagtgcgag aaaggagagt gggaaagaag gaggaggaag 12181 taggaagagc tgtgactaca gtgcagttct aagaaagttt tggccaggtc aacagggagt 12241 cctcatgcaa tagtcatcca tgacaccatc tcatgtgcag caggaacggc ccagctctag 12301 tgcccctgct atattcagtt accatgggcc tgaaggtgtg acagctggag catttgtcag 12361 tcatgcatgc cacagaggac tcacttgaag agtgatctga gtggtacccc tccatggccg 12421 ctacactgta tatgagcaga gatgaagcag aaacattccK cctggctgac cttctttcat 12481 ttattcatcc tccgtcttat gaaaagaaaa gtgagatgtt agagaaggtt atcacaggac 12541 agggtcatta aagctgggtc ctaagggact gtctcaagca tcattgctgg ccagcagtca 12601 cagcaaRcca ctttcattta tttttggtat ctatgttgag ctctgctgcc aggaatctgc 12661 catcagtgat ccaagaggct ccatggtaag gctttggaat cacacagacc tgcattttat 12721 tctcatctca gccatttggg cattgcataa cattgtataa gtctttcact gatgtaggtc 12781 tcacttttgt tatctgaaaa atgaggataa ccagacctat ctcatgcagt tgttataggg 12841 attaaaaaac atgatgtaag catagagtct ggcaccaaca gtaggtgctt taaaaaaaaa 12901 aacattagtt ccttccctat cccactaYga cattattagg ggaaaagaaa tcttttctta 12961 gatgtagtaa tttttctcaa actgagtaat gttaaaaaac ttagggcctt agttctgtaa 13021 actccagcta tctatagcaa tcagggtgaa tcagaatgat ctccactgaa ccttctaatt 13081 cacacccatc actctttcta aagcagcaat ttgtgattaa tctcactcta gggctaaatc 13141 agtcccaagc gcttacaagg cacttgataa agaagctctc tgatttatag caaacaccat 13201 tattgagcgg tggcagggag aagccattgg ggatttgtct tgctggaaac tctctctgcc 13261 ggagccattt cttctatttt cctgggtaag agctcaattt atttcaaaat agatggatgg 13321 agttccttgg tgaggtagga ggaagggagg acttagagaa tttttaaaaa taaataataa 13381 tacttaatat tttaaatttg tgaaattctt tcagcttcca cagacatcag gacttgagag 13441 aaggctaggc atatagtagg ccttcaataa acgtttgtag aagtgtacaa tcatctcatt 13501 tactcttcac agcagcccca ggaagtacac tgaggccatt cttcccattt gacaaagagg 13561 gaatttgagg ttggcagcta caaaacagca aagctgggac tttctcttta tttatttatt 13621 tatttattta tttatttatt tatttatttt tatttttaat tttatttatt tatttatttt 13681 tgagatggag tctcattctg tcacccaggt tggagtgcag tggtgcagtc tcggctcact 13741 gcaacctctg cctcacaggt tcaagagatt cttgtgcctc agcctcccaa gcaggtggga 13801 ttacaggtgt gcagcaccgc acccagctaa tttttgcagt tttagtagag atggggtttt 13861 gccatgtttc ccaggctggt cttgaactcc taacctcaag tgatccgcct gccttggcct 13921 cccaaagtgc tgaaattata ggcatgagcc accgcaccta gccagagctg ggacttttca 13981 tgcagatcca ggcctgatcc ttatccttca ccatgYcatc accctcaatg gtccaggagc 14041 agcactgtca aacccattcc tggagcacag atgtctgaag cactgtctca tcaccaaact 14101 ggaaacctgg ttagcgaaga ctgcagtttc ttttttgcct attgtttggg cccatgcggt 14161 tctattccag aacacgttta tgatatattt gcatctcgca cRcagtccgt cttcctgact 14221 cctgtctact taaagcctgg ctctccttcc agcgaccttc atgaatagct gtcttatctt 14281 tgcttgagca tctcctatga ctgagagctc cctactcggc tgcccagtgt caagagctct 14341 tcttatttga ttgagcgaac ctactgcccc tggaatgtaa ttcccctgga ctgtagactt 14401 ggatccaggc agaatcgtag cagcaaaagc ttattaggcc ttcccactta caagctgtgt 14461 gacagagggg aagggattta atttttttaa gtcctggttt tctcaattat aaaatggaac 14521 caatactatt ttatcagtag gaatactttt aggtgcaagt aagagaatac ccaattaatg 14581 gtggcataaa taataaagac atttaatatc tcacttcaca aaaagttttg aggcagacag 14641 tgccagcatt gtcctagcaa cccagtgcca ctggagttct ggggtcctat gttggtatcc 14701 ccaggatttc ctgggccatg atatcttgac acaacacttg gaaggcaggg ataaaagaca 14761 taggtaaaaa caaacaagca aaacagactt ttctgtggcc tctctcttct cagggaggaa 14821 aatattcact atccttggaa agtacttgac tttgttctct ttctttttca tcagatctag 14881 ttaSacacct gttcctagac ctggccctgg cttaggtgaa cagcattaca taattgactt 14941 agacattcat gatgtctcgg gcagggaata ctgccaccta aacaaaatga aggtttgcag 15001 aaaaagaaga ggaaaagtgg ctattggctg gtgatatggt ttggatctgt gtccccatcc 15061 aaatctcatg tcgaattgta tgtaatcccc aatccccttt ttggaggtgg ggcccagtga 15121 gaggtgattg gatcatgggg caggttctga tgagtggttt agcactatcc cctctgtgct 15181 gttctcgtga tagtgagtga gttatcacaa gatctggttg ttttaaaagt gtgtagcacc 15241 tccccacccc tcctgctcct gccatctgag gtgctttgct cccctttgca cttctgccat 15301 gattttaagt tccctgaggc cttcccagaa gctgatgcca ccatgcttcc tgtacagcct 15361 gcagaaccat aagccaatta aatctgtttt ctttagaaat tagtctcagg tatttatttt 15421 agcaattcaa gaacagacta atacagctgg gcaacaacag cattatagtg agtgcaaaat 15481 tggataatat atgcaaagtg tttagtagag ttcccaacac cttctgcttc ataaatgtta 15541 actattacta ttgcctacta taatgataaa ctttcataaa aagtaaccag ggtccctctg 15601 atcatctctt ttcccactta ggacttctgt tcaccttcaa ttatgcccta ccttgatagt 15661 catgctcctt ggaagaaaaa gacaccctag gtagggctat cttattgtct aatcccatgg 15721 agtgctactc acatgttact ctagggaatg taccctatgg aggtgtgact gttagcctca 15781 gtcctgaata ggagtaaaat agttcttcct catctgtctt cactatttca ttttatctga 15841 gatgtggcct ccccttgtcc ttggtatatt tggtcctgat ataactttat agtttttatt 15901 ttgttttatt tttgtcatta gcacttttca taagtcttgc ttagaaacag cctgaatcaa 15961 cctcttttca acatcgtggg taaaagaggg agaagcggtt cccttcaagt gagtcagtga 16021 caaattgtgg cccctgagct tgaccatggg tgctctatct gttcttctta agtcagtggg 16081 gctgtgggga gggggcctcc ccagctctgc tgggacattt gaaatagttc aaagaaagag 16141 acctcaccag tagaggacag aaaatccaag gtgggtaatg gctggttatt acttaaagct 16201 atcttgagta gaaaacaaaa gaccRatgaa aaccccttct tacacttgtc tcttgaagtt 16261 ctctgcctta caaaagaatc tcttaaataa atggagtcct ggaaagaaga gatcctgctc 16321 tcaggctttg gctccaaaat tttcctttat aaatcacgtg tggaagtagg tggagcatac 16381 accacaaagc gagagggaaa gaggagcagc cagcagtggc cactcaccat gtgccaggcc 16441 cctaaaggaa taaacccact gccttctcag ggtgttctat gggcaggtgt tatagaagat 16501 ttgttaagag aggaagtggt cccaggaaaa caaagtaatt taaacgacat ttccccgcac 16561 cacactgtaY tgtcatgctt tacaaaccat ccaaccagcc agagccaacc tcccaatgct 16621 taatgcttcc aaatagcatt tcatctgaga cccaagagct tgcaaggcca aggtaagtct 16681 tacctgggag gtctgagtca agtcactcag actctctggg ctcaatttcc tcattcataa 16741 ataacatggg ggccgggcgc ggtggctcac gcctgtaatc ccagcacttt gggaggccga 16801 ggcgggtgga tcacgaggtc aggagatcga gaccatcctg gctaacaagg tgaaaccccg 16861 tctctactaa aaatacaaaa aattagccgg gcgcggtggc gggcgcctgt agtcccagct 16921 actcgggagg ctgaggcagg agaatggcgt gaacccggga agcggagctt gcagtgagcc 16981 gagattgtgc cactgcactc cagcctgggc, gacagagcaa gactccgtct caaaaaaata 17041 aataaataaa taaataaata aataaataaa taaataaata acatgggaca attttatctg 17101 cctcatagaa ttgttgaggg agtcaagcaa gctactgcat gtatttcaga gcYtggtttg 17161 taagaggtct caataatgaa tgctagccat tattattgct cttgttactg ctcttattgt 17221 tagggacttg atcttaccaa gccctaatga ccccatctcc agaacagtct gacccaagaa 17281 cgctctgcag agaaagtctg agcaccgcca agcacacttc ccaagactgg tgtgtcttcc 17341 tagcctgcRt ttccttcaca tttcaactcc gacagatttc tgtgttctgg atgaagctgt 17401 tgagcgttaa ctctgcaatc tgttctggct gttcaataaa cttctcttcc cggacaagct 17461 gtcacatgca cgtaaatatc actttatgcc tggactttga tttccgagtc aaacttctac 17521 ttcatggtgg ctattagggt cattcccaat ccagagccta ggaatcacca ataaagcatc 17581 aagcattcct gtggagtgtg gatgaaaaag atgaggatgc cagagctcct gccctcaagg 17641 agctttcagg ccaatagcca gcttgcagca caatgggata ggtgcagtaa tagagctctt 17701 tacatggcca caacatacag gtgaggataa actgagcttt cgagaggctt agttacttgc 17761 tggatctcac agctggtaag gaaggcagga tgtgaactca gatcttctga ccttgaatcc 17821 tcagtggttt cctaaactat aggtttgtgc aaaagtaatt gccttttaaa atttgccatt 17881 taaaagtaat gaaaaaaaaa aagcaactac ttttgcacca acctaattgt tcccctgaga 17941 gaaggagttg gttcattgtg ataagctcag gtcaaagctg gtggcccatg tgactttggg 18001 tacctgttag ggtccaaaaa gtaccctaac tcctgtgttg ccaagggtca actgtatgtt 18061 cctgaggctg ctgggccttt ttcatgaata ccttttagtt agctgattgg ctcattgcaa 18121 agggagctgg tgttgagcga tgagatcatg gaaagtttca gggactatgg agcaggagaa 18181 atgctctaKg cattcaaaca aagcaaagat cccaaataat tgtttccctc gttgccctgc 18241 caattgttct cacttcttgt gtgtgaaggg aagcatatta aagacagtga aagcctttga 18301 gtctcacaga cctagctaaa ctcctggatt actgtgtgac ctcggtaaag ttacacagtc 18361 ctgtgaaccc tcattttctt atctgtaaat taggagaata aaacatgcct cacRgggttg 18421 ctgtgaagat taaaaggaga ggaaggttgt agaatcttgc cttaataggg ctcaacaaat 18481 actaattccc attttcccag cccatcatct ggcgaatgga ttggtgattc caggaaaaga 18541 ctggccttat ttctccagat ttaaacatta gaatgtagaa attgatggaa atcaggagca 18601 ctctccagac aagagccgta atggattaat agaattagat taattattag tagtagtagt 18661 attgaaactg agtcttgctc tgtcactcag gctggagtgc agtggcacga tctcggctca 18721 ctgtaacctc tgcctcctgg gctcaagcga tactcctgtc tcagcctccc gagtaactgg 18781 aattacaggc acctgccacc acaaccacat ctggctaatt tttgtatttt tagtagagac 18841 aaggtttcac catgttggcc aggctggtct gaaactcctg acctcaagtg atctacctgc 18901 ctcagcctcc caaagtgttg ggattacagg aatgagccac tgtgcctggc tgaattaggt 18961 taattaaaca cacacacaca cacacacaca cacacgaatc agactaaaac aaaacgtgcc 19021 acaaataaaa gtttcctttc ttctcacact caggtaggaa gacatcatca tcacttctga 19081 gctgtagcag atcagagcca aacttttgga agtgacctct cttaactaat aatctcacag 19141 cccagatgaa gacatgttag aatatattaa caagaatcag cacaatgcag cacttgggat 19201 gttcagtaaa gcatatacac gttactatat ttaaacccat aataattctg ggaattgggc 19261 agggcaaata ttactatcct attttcccaa ataaataaat gagactagtg atgttgccct 19321 taatactttc aaggctacca taacatcaga aaggaataat ttggaaaaaa ctaaactcaa 19381 tatttctgtg caaaagcaat agttacttaa aaaaatacaa ccttaagtat agaataacag 19441 aatccttaag tagaacatcc accatttcta acctatgaaa atatgattat actttaatat 19501 attggtcaaa attaacaagt taactttaat attctgaagg aagaaaaaaa caaatctgat 19561 tttagaccaa tgctgcccag gacaaggtcc cgggcctctt gtggtctatg aagatggtat 19621 taggaacctg tcagctatgt ttaatatttc aaagagctta actaaaaatt ttatattttc 19681 tctcacataa ttaggtactc aaactaatta aaataatttt ttttttcttt tggctggaac 19741 tttgataaca ccagagatca cgtgatgatc aaaggccctg cttggtcttt gatgatatca 19801 gagacatcct aagacctgga aacagagctg cactgtgact tatgccccat gctctgcagt 19861 ctcctaaaca gctagtgtgg tgagaacacc tgggcatgag tctagacaca ccaacccttc 19921 aagacagaac ttagtggtgt aaaacccctt gcacgcagag ccagttaatg taaaaggagg 19981 tctgggtgat tcagaggctg ggagcgagcc actggcctaa cttttctgat ggaagttagg 20041 gggcaaagtg tagatgggta gaacactgac agagttttct tcccagtaat gaagtgggag 20101 atttatctca tctcactaca gattaaagaa ttctctaggc tctcacaaaa acatgttatg 20161 aggtgattaa cagaaatttc atccctcaca tgtatacata cgcttaaaat ggatattttt 20221 accatctgtc atagactatt aaaatgggtg cttttaaatc agggaaaagg tgttggccct 20281 gctgttcaca agtgaagggt gaagggaaat ggacattttt catcctcact tcctatatga 20341 gatttgttca Ygtaagtggc agtacatgga ggaagaggac ggactttgga gtcagaagat 20401 gggagggttt gaaccagttc tgtcattgag agttgagtac tgctggacac acattgacta 20461 atatttttga gcttcggtct ccaggtaagt ggaggtaaca gctccctttc caaagactgc 20521 agtattgcca aaagaacact ggattacaaa tcagtgaatt ctttagttcc aatcccagtt 20581 cagccattta cttgaatgca tacttggacc acttgcctaa ttctccaagc tttagttttc 20641 tcccctacga gtaaatgatg ccatttgtcc ttccaatctc ataggctggt tttgaggata 20701 taattcagta caaaacaaga caaaacaaaa caaaaaaacc ttgtaaacgc taaagcaaat 20761 atgctaatga aaatttgcta tcatatcaat ataaaattta agctactttt ttatcagatt 20821 aaatgtcatt tcagataaaa ttgtcaaSga atcatcttgt ttatttgcct gctgaaagga 20881 taaacattag gttttaattc tagttctgcc acttacttcg taagccccgt ggttgcatct 20941 ctcctaacac gcagtagcca ttctgtttgg gtggtgttga ctcataccca tcatcagctt 21001 gaatgttgga tcctgatagg tccaagccaa tcaagataat gccatcccct gccatggtga 21061 ttgcttcaag ggtgcagtta gagtgttaaa ggctttgttt caatagttgt ggtgtgagtc 21121 agtcacacat ccagctggat gtgaaagcat gcaaccctgg gagctactgg caaccatctg 21181 gatatcacca gggaacaggt gagaaagact gcaaagaaaa aagagccctt gctctgataa 21241 tatcatgatc ccctggatta aactgtgcct gaagcagcac actgctgggc ttttctgtca 21301 gtttgaggca acgaattttc ttggttgggt ttgtgttggt tcctctgttc ttacaagtaa 21361 aaaaacctta agaaatacac catgtaccct tgagtaactt ccattacccc tctaaacttc 21421 agttccgtga tctataatag ggcatagtag aatagaatgc ctaccataaa tagggtcact 21481 gtggggttca acagtgcttg aaaaatgctt agcaccacac ataaatgata tggtttgact 21541 ctgtgtcccc acccaaatct catttcaaat tgtaatcccc atgtgacaag aaaggtaagt 21601 gattgaatca tgggggcagt ttcctccatg ctgttctcct gatagtgagt gacttctcac 21661 catatctgat ggttttatgg ggcagttttc cctgctctta ctcactctct cttgcctgcc 21721 accacgtgag acatgcctct tacccttccg ccatgattgt gagattcctg aagcctcccc 21781 agccatgtag aactgtgagt caattaaatc ccttttcttt ataaattacc tagtctcggg 21841 tatgtcttta tagcagtgtg aaaatggact aatagtacaa agtatgcatt cagtatatgg 21901 taacaatttt tattacattt gcagctctag actttgtgtt aaatgcttta agtatatcat 21961 ttcacttggt cattggtcaa cctaggagga ttttttttgt ccccatttta caattaagaa 22021 atgagggtta gagagtttgc atgacttgtc cagggttcca caactacaga agcagatttt 22081 acagagtatg attgtttctc ctttttttca atcctttgaa cagataatta ttgtacagtg 22141 tcaatgttaa ttgaatgcct ataatgtgca aagcattata agtatatagc agtaaatata 22201 cacactgtcc tttagtttta gaggatagtc tcaccctatc tgaattatag aaaagatcgg 22261 gttgagtttg tgccttggat ttattagcat catgctccta acaactaagt taaccagcct 22321 atcatctaaa tcctataggc acatgaaaag tattgacagg aacaaagtag ttctgcaact 22381 aagtgtagaa catacagctt atttccatat aaaatttaaa gtatatatat acatcttgta 22441 tttcaactgc tatttaattt cttctaaagc attgagctga actgtaacat ttcttttaca 22501 tttaattcca ctggttaaaa aaaatctttt tcatatacta taaagatatt atctctgctc 22561 tttctgacat ggtgtcaact tatatatgtt tctagcaagt atgaacaaca caattagaag 22621 tgacaatggg aatggaagaa aaagtaggcc gttgctacat tattttccta ggaaatctgc 22681 aggaaaatct aatgctgtgt tttactgttt acctttaggt gacattctcc aagtgtcttt 22741 atatgttatg gagtgccttt tacaatactc caatcacaag gagtgtaaaa aatgattata 22801 tggagaatag ttaatatgaa cctcttcatg accaatgttg tctcgtgtgc agatcaggaa 22861 attccttaca agtaatgtat aataatccct gagaaacata aacagcctct gaacttatct 22921 tcttaacaac tagatatttt gtccaagaag atttaataat gtcaggacac atcccaaatg 22981 agatttcaca ggctttcaca ggcaggggga gaggttctac tctcctacac tgcctcatct 23041 atgcttttca tgtcaatttt gatagaaggg tctgagagaa gaacctataa aatcaaccta 23101 cagaaaacac aagtggtccc tgatttcata atgatgagat ttttacttat attgaagcca 23161 tatgtgggga agctaatgaa caactgagaa tactttgttc cttgtcttga tagcttagtc 23221 ttagatatct gagagttgta aaaaaatgga cagatttgta gtcagataga ctcagctttg 23281 ttctatctag gtgagagata ttggatatat tatgtaactt ctcgaagcct atttgtcatt 23341 gtaaagtgag aataataaaa cctagtaggg ttatggaata aagataaata tagggcccag 23401 ttcatagtag attcacaata caaagtagtc cctttcctct ttaattctct aagaaaatat 23461 ttatttaata taatgtattt caagaaaaat gcccttctta gaaatataac ctaagcatca 23521 ctagacttca ctagtttggg aatacaaata ttaaataact cgtatttcca catttatata 23581 atgcagcaat ttctgggcac cactgggggt atgtcttgtg ctgcttctct tgtcgttttc 23641 ctccagtcgt cttgttgata tctgctgctc aggaaggtca acttggggac agtgccttgc 23701 ctcagcctct tttgagggac agtgccttgc ctttgcctct ttttcttctc tgggaacccg 23761 agattcccaa atggtaatct catggagcaa ccaaatgaca taaacttctg ttaagatttc 23821 agtgcaccag gaacacgctg tatctctgtg gaaatgccct ctcccccaat tctgtttctt 23881 gctttgtcat ctgaaccaca aactgtactt cttttgcctc cctatgaaaa tggcttctgc 23941 cagtagcatt ttctccagtc atccacaggt gaagacaagg aaattctcta tcctgaggcc 24001 cccttttcca cataatccca ccccaatgca aactatttcc tgcaaacaga taccttcaga 24061 ctgtttcccc cttcatcata acgacccaga cttagaaatc cagtttaggc tcagttgaaa 24121 cattctctac tataaaaact accgtatggg ctcatttctc atccactagg ggtctgcctt 24181 ctaaatcaaa agcaagtaga agacagagta aaatgtgtaa tataaattta ttctgtgaca 24241 ttttcctcat tgaagatatt ttaacataga ttaaaataca tcaatatttc atgaaaaata 24301 aattctagaa gaatttagat aatatctgta atgtacatga tttgaccctg aatatccttt 24361 tttttttcac ttcaaacatc attttttaaa aagtaacata aaatgataag gactgcaaca 24421 tNcttcatat atcttgtgtc tcataaattt taattcaact gcccgttctt ttctcaacta 24481 tgtatgttaa tggtatttgc tcctgttttt gaataggaag agtatccatt ttctgtttct 24541 tcgtgatatt taggtcttct ttctctgatt cttcaagaaa atgcttcgtg ctgagtttga 24601 atagtaatcg agggtctgga ttagacagtg gtggacaatt acacatctct ctaattttga 24661 gagcctataa agaaataata aaataaaaaa atactatata tatacatcaa tgtattcaga 24721 ttgtttcagt aatccctaat atgctccatg taaaacaaag aatgtattgt tattttttta 24781 ataaaaggta tcttgattat aacacataaa agagaaccac tgaaaaatct acagtgaaca 24841 gttgttttca tgatttggtc aaatagtatt attttaaaaa caacaacaat agtattaata 24901 atctgtaaca actgccctaa tgctgttttg agggtaaaca aatcttagag atacatctat 24961 ggtttcagtt aaactctagc agaccggaga atcattcaga tttaaaaagg ctctatgaga 25021 gatttttttc aagaaaaact gcagaacata gatgactgaa tatactgaaa aaagatatac 25081 ataactgata cagtcttggg taaaattgat gataataacc tagtgatatg gtttgcatat 25141 gtctccaccc aaatctcatc ttgaattgca gttcccataa ttcccacatg tcatgggagg 25201 taactgaatc atggaggtgg gtgtttcccg tgctgttctc atgatagtga ttaagtctca 25261 cgagatctga tggttttata aagggcagtt ccccctgcat atgctctctt gactgccgcc 25321 atgtaagaca tgacttttct cctcattcgc cttccaccat gattgtgagg ccatcctcag 25381 ccatatggaa ctgtaagtca attaaacctc tttccttcat aaattaccta gtctcaggta 25441 tgtttcatta gcagcatgag aatggactaa tatacttaga aaagtaaaca aatcaaaatc 25501 atgacaattt ttaactcYag gagaaataaa acattgcaaa ggaaggaaaa gtaatcacag 25561 tgtactatgg ggctcagcta tgactagtgc ttacagttta aaataccaaa tcttgatgaa 25621 accaaaaagt acaatttcat catactgaga aggggagagc tgcatgtgtg tgcacatgca 25681 cagggtgtga cactggaaag agagggctta cgtctcatcc tgtaaggtgg aaaataatta 25741 aggcccaaaa ttgaagttag aatgtagcaa cataagcatg ttatttagac acaatgggaa 25801 atactaaaag aatcgtccaa tagaattgga aatagttacc cctgaaactg atggcagggt 25861 tgagggactg gctgctgatt taagtaacta gccttagaac tatttaactc ttcaaagtgg 25921 gtatatggat aattttaaga tataagagcc aaaataattt ttaaggataa atggtcttaa 25981 tatttaggag ttttaaaaga aagacattta ggggaaaaag ctaattcagt tttttacgac 26041 ttctggcttt ctgatactga tgtgtcttaa gggaagtaaa taaggcagta aaggagacag 26101 tgtttgaggg actggtaaaa tcttagaaag actatccagg caaggcctca ctgataggat 26161 aatgactttg ggggtcaaga gggggacaga cctgaaggac atgaggaaag agaccatgtg 26221 gcaacctagg gaaaaatcat tccaagaggg agctgcgagt acaagggaga tgggagcgtg 26281 cctggggtgt tttggaacag tgaagaagca ggtacagccg agtggagcag ggtggagggc 26341 aggagcagat tatgtaggac ctcacaggtc atgctaagga ttttaagttt tactctaaac 26401 agcctgcctc taatatttgt ggggtccatg gaaagaatga aaatggaggc ccagatacca 26461 tgtctctaaa cacctaaaag cagtaagtca agctaataca ctactactta aaatctgttc 26521 tattctccta ctttgaagaa tacacattcg aaattacctg gaagtccagg tacaaaacta 26581 gaattcttga atttcagaac atgtaagatt gcagggagct tactgtgtag ctcttgccac 26641 tagcctgcca tctgccccct ctcccagccc tagcttatct ggcactgtaa agggccttgt 26701 gtgWatgtgt tcaaggaaga ggtccagatg ggccctgaaa gcaggctcaa acatatctgg 26761 gcaaggaatt ccattattcc agataccctg agtggggtat ggtaggggca caggttcttg 26821 tatgctaaca tttcattgag tcccacagga gagagggact tgtagtcaga tgcgagccag 26881 atagacgttc tctaagtgaa tggggtcagg gcagaagctt gggtctagga gcacttctag 26941 ctctgattag gctctgagtt accaaggtaa gctggagagt tgaaaaaaca ttacttaacg 27001 tgaaattctt cagtggcagt ggtcttgtct tatttttctt tgtatttcac agcagattta 27061 agatttcctt atatctagtg agtgttaagt aaatgtttaa gtaaactgaa ttgacacaac 27121 aagaaaatgt ttcccaacta tagcacttac agcacttaag taaacagaaa gtcagatcct 27181 cagctaaacg gtgacctact gtccaaactg ggataccttt gagaatgaaa tgagatgcta 27241 gcaagatttg cactgagaca tcaggcatga gccatgactg tctctgcaaa attgggacgt 27301 acggtcactc ttgcattagt tcctttacaa tgatgttaat tttctttccc aagtgagaag 27361 tttacctgtc atggctgcta tatcagtgta gtgcctatgt ttaagcactg cactggcatc 27421 agtaaagggg gagagtatgg agtccagcag gtaacaactg gcacagctga gtgtggcaat 27481 gagagatgca aagcaacaaa gagaggaata ggatgccatc ccctaagatc tttgtgtatt 27541 cagtaaaaac tcttctctta tccttaaatt cgcttattca gtctttttaa tacaacaaat 27601 atttagaaca ccacagtgag taaggtgcta ggtacacatt ggtcagaata gtcatggtcc 27661 ctgccctcat gtaatttact ttgtatttct ccgttactgg gcattagaat tgttcccaca 27721 gttgtgtcta tttggctttt ataaattacc ctgctataaa aacttttctt taaaaaaatc 27781 ttttctcacc tccatttgga gatatgtgaa gtctaacacc caaaatagaa tgatctgatc 27841 aaagagtaag cacaggtaga ttatactttt tgttatatag gaccaaactg ctttctacca 27901 gaaaggcttt atcaaccttt aatgtcacca gtaatacagg catacttgag ttattcacag 27961 ttattcacat aacatttcat gacttttata tagataatta cataatttca aacctcagaa 28021 tccttagaaa atatcagctc aattttacag atgaggaaac tgagtctcag agaagttaaa 28081 tgccgggcaa ggaacaaaaa gctggcttgg taaatgtttt taacagcttt atttgctaaa 28141 acttggaaat aaccaagatt tccttcgata ggtgaatgga taaactgtgg gatatccaga 28201 caaaagaata ttattcagat ctaagaagaa attagctatc aagYcatgaa aagatatgag 28261 gaaccttaaa cgtatattgc taagagaaaa aagccaatct gaaaaggcta catgattcca 28321 actatatgat attctggaaa aggcacaact atggagacag taaaaagatc agtggttgcc 28381 aggggctagg gggagggagg aatgagtagg cacagagtgt atttttatgg cagtgaaact 28441 actctgcatg atgctataat ggtggataca tgtcattata catttgtcaa aatgcactga 28501 atgtacagca ccaagagtRa accctaatgg actttgggtg ataatgatgg gtcaacatag 28561 gttcatcaat tgtaactaat attatcactc tggcatggga ttttgatggt atgggaggct 28621 gtgagtatgc ggggacagat gtataaggga aatctctata ccttctactc aattaaaagt 28681 tgaagcttta gagtctaaaa ataaaagagt ctactactaa aaaaaaaaaa aaaaaaaaaa 28741 aaaaaagctg gcctggaagt aaaaaagctg ggtttagaac ctgtttKgtt tctaccgctt 28801 ttgctctaca tgctttttgt gctcatgctt ttttgtatca catgatattt cttgagtaaa 28861 ttttttactg aataaatgta ctttggagat gtctgagcta ggtttYttta attgctagaa 28921 acactatatg ttcttcatac aggttttcta tcactacttc ttcatgtgtg aactgtttct 28981 cctccccaaa tatctatcaa gcaRaatcct gttatgacca tacatatttc tatcaaatct 29041 tcatctactt tgcatagtaa gattctattg gatgtcttgg taacttattt tttctttttt 29101 cctttccttt ccatattcat tttatatatt tcagggcgcc aatgtctttt tatttttata 29161 aattctaatc tatcttatta aatatatctt catctcttca aaagtgagca aaattttcct 29221 accatatagc tagaatatgt ctttccactt cctttacttt gttttctgtg tttaactcca 29281 cgcactgcac ataacaggca cttaacaaac gcatgctaaa ttttaaacaa acatttatag 29341 aacaccagct atgaataaat cattatgata aatgtcatag agaaaatact cttaggagtt 29401 tatggtttaa gaaaaagcag gaatgtattt taatagcaag aatatatggt tctgagaatc 29461 ctgaggaaga tttgaagtta aatatagaat tagccagcct aaagactaca actatgagtg 29521 aaagaaacta acatctactg ttcactttct atgtgccttt cactgcgtga ggtattttac 29581 acatctaaat tgacattgga atttgaacca cttttgaaat cttgggcctg acataaaata 29641 cttatcatta aaatgtctat gccaaagaga gggggacaag gcaaagaaga cagcaggacc 29701 ttacctacag aaatgcacaa gtatgtacat ccaacatcta ggagatattg ctatcctgat 29761 ttcacatatg aagaaaacta aaggttggat taggtaactt tctccaagtt acatggctga 29821 gtcagaatta aaaccgaaga ctcctaagac cactgttatc tttatattac tatttcctgc 29881 gaccatcttt ctcccgttac caactattaa tgtcctacat gctaaatttc tataagggag 29941 tggaaggact gttcaattct actgccaatt tttctatttt tcacccacta ttatattgct 30001 tatcctgcct attattacac atcatgcaat catttaacWa atattcacta atcatctcaa 30061 cttctcatag gtactatgga tacagcagtg tacaaaggcc ttacacacta gggtaaaagc 30121 caataaacaa ataaggtaat tttagttaag tacatgaaga aactaaagag tgaggtgtgt 30181 tggacggaca atgagtacat ggaagggaag cgatttaaga ttatgggatc aRagaaagcc 30241 tccccaggac agtgacattt gcctaaagaa ctgagggaag aatgtttcag acagagaaat 30301 cagcaagtag aagagctgta aggaggacac tagcttaatg ggggacatac cctggtcttg 30361 tatgtttcct aaaccaagga aagcctaagg aaaggggcat gtggtgaagt tggagagcta 30421 ggcagtggcc aaattacgtg cctggaagac ataggaagag tctggatttt tattctaagt 30481 tagatgagaa gccactagag ggttttaacc aaggaaagga cattacaatg atcactctgg 30541 ctacatattg aaaataggtt gttaggagtt gaggtgaaac gtgacatcgt gaggtgaaaa 30601 gtgacaacag gaaatgactg cggtaacttg ggaggagatg atggtgactt ttactaggaa 30661 aggagcagtg gcgaagttga gaagcccaca gattcttaat gtacttgtta aagcagtcaa 30721 gattttttca tgaataggac acagaagtga aggaaagagg aactgaagat gagtcctaaa 30781 tttcctcttc tgttttaata gcttttcttt tatgatgctg ctcatgcatt tgaggataat 30841 taacttgctc acagtaaata attactgtaa tataatatcg tattgtcaat taatgacccc 30901 agtccataaa ttcttttaaa gttattgttt ttatcaaatt gtcaaaacaa aatcatttat 30961 gcttgtaaaa tgaatcagaa acttaataac atacctttct acattttgaa ggtagaacta 31021 attagtaact aggcaattgt tctctgaact tctgaaaaaa ttctccaaat taaatcccat 31081 cagggctagg cgtccttttc tttgctaatt tattatgact ctatgggttc taatagtttt 31141 ttaaatttga tttatttata ccttacttct ttctaaagta atttagtaa.t ttgtaatttg 31201 taaattagta atttgagaag cttcattcta gctataattt ctactcctag ctgcatccac 31261 tctagcaatt cccctccccc ctcaacacac atatacttta attacttctg attttgacct 31321 gagctattaa ttaacattat ctaactaaaa ataacattct cccaaatatt tcagttttct 31381 tgcatgttac cgtacctctt ctcctgatcc tatttacatt ttactttgtc taactaatct 31441 aatgattatg actttgacta aatttcccaa agaatcaact actgtcattt tgcttatttc 31501 tgcttaattt tattaattat attttcccta tttgagacat ttatagttct atatttcttt 31561 tctctttttc taatatagac atttaaactg ataaagtttt ctttaaatac agatttagta 31621 aaaactcatg aaaatataac tacatcatta taaagttcat tgattacaag ccatcctctt 31681 attgtttata gatttctctt ttgctttaca tgtgcRgaat tttaattttc atgtggttat 31741 ccatctttta atttttgtta tattaatttt actatactat gttctgatga ttggaaccat 31801 aactttgttt tatttattta tttattattt caataggttt ttggggaaca ggcagtgttc 31861 agttacgtga aaaagttctt aaatggtgac ttctgagatt ctggtacacc catcactcaa 31921 gcagtgtaca ctgtacccaa tgtgtagtct ttttttttga gacagagttt cactcttgta 31981 gctcacactg gagtgcaatg gcgcgatctc agatcactgc aacctctgcc tcccaggttc 32041 aagcaattct cctgtgtcag cctcctgagt agctgggatt acaggcatga gccaccatgt 32101 ctcgctaatt tttgtatttt tagtagagac agggtttctc catgttggtc aggctggtct 32161 tgaactcccg acctcaggta tctcctgcct cggcctccRa aagtgctggg attacaggcg 32221 tgagccacca cgcccagccc cagtgtgtag tcttttaccc tcacccactt ctcactgttt 32281 cccctgagcc cccaaagtcc actgtatacg tcttatgcct ttgcatcctc atagcttagc 32341 tcccacttat cagtgagaac ataacatttt tatattatgt acagatattt ttgtccaagt 32401 tttatgatca atattttcat gaaagatgtg tacttgaaaa tatattcctg ctggagccaa 32461 gatggccaaa taggaacagc tccagtctac agctcccagc gtcagcgacg cagaagacga 32521 acgatttctc catttccaac tgaggtactg ggtgcatctc actggggatt gttggccagt 32581 gggtgcagga cagtcggtgc agcgcaccga gcgtgagccg aagtagggca aggcatcgtg 32641 tcacccggga agtgcaacgg gtcagggaat tccctttcct agccaaggaa aggggtaaca 32701 gacggcacct ggaaaattgg gtcactccca ccctaatact gcaattttcc gacggtctta 32761 gcaaacggca caccaggaga ttatatccca cgcctggctc aaagggtcct acgcccacag 32821 agcctcgctc attactagca cagcagtctg agatcaaact gcaaggtggc agcgaggctg 32881 ggggaggggt gcctgccatt gccgaggctt gagtaggtaa acaaagcagc tgggaagctc 32941 gaactgggtg gagcccactg cagctcaagg aggcctgcct gcctgtgtag actccacctc 33001 tgggggcagg gcatagccaa acaaaaggca gcagaaacct ctgcagactt aaatgtccct 33061 gtctgacagc ttagaagaga gtagtggttc tcccagcatg cagcttgaga tctgagaaca 33121 gacagactgc ctcctcaagt gggtccctga cccctgagta gcctaactgg gaggcacccc 33181 ccagtagggg cagactgaca cctcacaggg ccgggtactc ctctgagaca aaacttccag 33241 aggaatgatg aggcagcaac attggctgtt caccaatatc cgctgttctg cagcctccgc 33301 tgctgatatc caggcaaaca gggtctggag tggtcctcca gcaaactcca acagacctgc 33361 agctgagggt cctgactgtt agaaggaaaa ctaacaaaca gaaaggacat ccacaccaaa 33421 accccatctg tacgtcacca tcatcaaaga ccaaaggtag ataaaaccat aaagatgggg 33481 aaaaaacaga gcagaaaaac tgaaaattct aaaaatcaga gtgcctctcc tcctccaaag 33541 gaacacagct cgtcaccagc aacagaacaa agctggacgc agaatgactt tgacgagttg 33601 agagaagaat gcttcagacg atcaaactac tctgagctaa aggaggaagt tcgaacccat 33661 ggcaaagaag ttaaaaatct tgaaaaaaga ttagacgaat gactaactag aataaccaat 33721 gcagagaagt ccttaaagga cctgatggag ctgaaaacca tggcacaaga actacgtgac 33781 gaatgcacaa gcctcagtag ccgattcgat caactggaag aaaaggtatc agtgatggaa 33841 gatgaaatta atgaaatgaa gcaagaagag aaggttagag aaaaaagaat aaaaagaaat 33901 gaacaaagcc tccaagaaat atgggactat gtgaaaagac caaatctaca tctgattggt 33961 gtacctgaaa gtgacaggga gaatggaacc aagttggaaa acactctgca ggatattatc 34021 caagagaact tccccaatct agcaaggcag gccaacattc aaattcagga aatacagaga 34081 atgccacaaa gatactcctc gagaagagca actccaagac acataattgt cagattcacc 34141 aaagttgaaa tgaaggaaaa aatgttaagg gcagctagag agaaaggtcg ggttacccac 34201 aaagggaagc ccatcagact aacagcggat ctctcagcag aaactctaca agccagaaga 34261 gagtgggggc caatagtcaa cattcttttt tttttttttt tttttttttt tttttgagac 34321 ggactctcgc tctcgcccag gctggagtgc agtggcgcga tctcggctca cagcaagctc 34381 tgcctcctgg gttcacacca ttctcctgcc tcagccttcc gagtagctgg gactacaggc 34441 acccgctacc aagcccggct aaattttttt gtatttttag tagagacggg gtttcaccat 34501 gttagccagg atggtctcaa tctcctgacc tcgtgatcca cccaccacag cctcccaaag 34561 tgctgagatt acaggcgtga accactgcac ccggcccttc aacatactta aagaaaagaa 34621 ttttcaaccc agaatttcat atccagccaa actaagcttc ataagtgaag gagaaataaa 34681 atactttaca gacaagcaaa tgctcagaga ttttgtcacc accaggcctg ccctacaaga 34741 gctcctgaag gaagcactaa acatggaaag gaacaaccgg taccagccgc agcaaaaaca 34801 tgccaaattg taaagaccat caaggctagg aagaaactgc atcaactcac gagcaaaata 34861 accagctaac atcataatga caggatcaaa ttcacacata acaatattaa ccttaaatgt 34921 aaatgggcta aatgttccaa tcaaaagaca cagactggca aattggataa agagtcaaga 34981 cccatcagtg tgctgtattc aggaaaccca tctcacgtgc agagacacac ataggttcaa 35041 aataaaagga tggaggaaga tctaccaagc aaatggaaaa caaaaaaagg caggggttgc 35101 aatcctagtc tctgataaaa cagactttaa accaacaaag atcaaaagag acaaagaagg 35161 ccactacata atggtaaagg gatccattca acaagaagag ctaactatcc taaatatata 35221 tgcacccaat acaggagcac ccagattcat aaagcaagtc cttagagacc tacaaagtga 35281 cttagactcc cacacaataa taatgggaga ctttaacacc ccactgttaa cattagacag 35341 atcaatgaga caaaaagtta acaaggatat ccaggaattg aactcagctc tgcaccaagt 35401 ggacctaata gacatctaca gaactctcca ccccaaatca acagaatata cattcttttc

35461 agcaccacac cacacctatt ccaaaattga ccacatagtt ggaagtaaag cactcctcag

35521 caaattaaaa gaacagaaag tataacaaac tgtctctcag accacagtgc aatcaaacta

35581 gaactcagga ttaagaaacc cactcaaaac cactcaacca catggMaact gaacaacatg

35641 ctcctgaatg actactgggt acataacgaa atgaaggcag aaataaagat gttctttgaa

35701 accaacgaga acaaagacac aacataccag aatctctgag acacattcaa agcagtgtgt

35761 agagggaaat ttatagcact aaatgctcac aaaagaaagc aggaaagatc taaaattgac

35821 accctaacat cacaattaaa agaactagag aagcaagagc aaacacattc aaaagctagc

35881 agaaggcaag aaaataacta agatcagagc agaactgaag gaaatagaga cacaaaaaac

35941 ccttcaaaaa atcaatgaat ccaggagttg gttttttgaa aagatcaaca aaattgatag

36001 accactagca agactaataa acaggaaaag agagaagaat caaatagaca caataaaaaa

36061 tgataaaggg gatatcacca ccgatcccac agaaatacaa actaccatca gagaatacta

36121 taaacacctc tacacaaata aactagaaaa tctggaagaa atggataaat tcctggacac

36181 atacagtctc ccaagactaa accaggaaga agttgaatct ctgaagagac caataacagg

36241 atctgaaatt ggggcaataa ttaatagctt accaaccaaa aaaagtccag gaccagatgg

36301 attcacagcc gaattctacc agaggtacaa gaaggagctg gtaccattcc ttctgaaact

36361 attccaatca acagaaaaag agagaatcct ccctaactca ttttatgagg ccagcatcat

36421 cctgatacca aagcctggca gagacacaac aaaaaaagag aattttagac caatatccct

36481 gatgaacatc aatgcaaaaa tcctcaataa aatactggca aaccaaatcc agcagcacat

36541 cgaaaagctt atccaccatg atcaagtggg cttcatccct gggatgcaag gctggttcaa

36601 catacgcaaa tcaataaacg taatccagca tataaacaga accaacgaga aaaaccacat

36661 gattatctca atagatgcag aaaaggcctt tgacaaaatt caacagccct tcatgctaaa

36721 aactctcaat aaattaggta ttgatgggac gtatctcaaa atagtaagag ctatttatga

36781 caaactcaca gccaatatca tactgaatgg gcaaaaattg gaagcattcc ctttgaaaac

36841 tggcacaaga cagggatgcc ctctctcacc actcctattc aacatagtgt tggaagttct

36901 ggccagggca atcaggcaag agaaagaaat aaagggtatt caattaggaa aagagcaagt

36961 caaattgtcc ctgtttgcag atgacatgat tgtatatcta gaaaacccca tcgtctcagc

37021 ccaaaatctc cttaagctga taagcaactt cagcaaagtc tcaggataca aaatcaatgt

37081 gcaaaaatca caagcattct tatacaccaa taacagacaa acagagagcc aaatcatgag

37141 tgaactccca ttcacaattg cttcaaagag aataaaatag ctaggaatcc aacttacaag

37201 ggatgtgaag gacctcttca aggagaacta caaaccactg ctcaaggaaa taaaagagga

37261 tacaaacaaa tggaagaaca ttccatgctc atgggtagga agaatcaata tggtgaaaat

37321 ggccatactg cccaaggtaa tttatagatt caatgccatc cccatcaagc taccaatgac

37381 tttcttcaca gaattggaaa aaactacttt aaagttcata tggtaccaaa aaagagccct

37441 cattgccaag tcaatcctaa gcaaaaagaa caaagctgga ggcatcatgc tacctgactt

37501 caaactatac tacaaggcta cagtaaccaa aacagcatgg tactggtacc aaaacagaga

37561 tatagapcat tggaacagaa cagagccctc agaaataatg ccacatgtct acaactatct

37621 gatctttgac aaacctgaca aaaataagaa atggggaaag gattccctct ttaataaatg

37681 gtgctgggaa aactggctag ccatatggag aaagctgaaa ctggatccct tccttacacc

37741 ttatactaaa attaattcaa gatggattaa agacttaaat gttagaccta aaaccataaa

37801 aaccctagaa gaaaacctag gcaataccat tcaggacata ggcatgggca aggacttcat

37861 gtctaaaaca ccaaaagcaa tggcaacaaa agccaaaatt gataaatggg atctaattaa

37921 actaaagagc ttctgcacag caaaagaaac taccatcaga gtgaacaggc aacctacaga

37981 atgggagaaa atttttgcaa tctactcaac tgacaaaggg ctaatatcca gaatctacaa

38041 tgaactcaaa caaatttaca agaaaaaaac aaacaacccc atcaaaaagt gggtgaagga

38101 tatgaacaga cacttctcaa aagaagacat ttatgcagcc aaaagacaca tgaaaaaatg

38161 ctcatcatca ctggccatca gagaaatgca aatcaaaacc acaatgagat accatctcac

38221 accagttaga atggcgatca ttaaaaagtc aggaaactac aggtgctgga gaggatgtgg

38281 agaaatagga acacctttac actgttggtg ggactgtaaa ctagttcaaa cattgtggaa

38341 gtcagtgtgg cgattcctca gggatctaga actagaaata ccatttgacc cagccatcgc

38401 attactgggt atatacctaa aggattataa atcatgctgc tataaagaca catgcacacg

38461 tatgtttatt gcagcactat tcacaatagc aaagacttgg aaccaaccca aacgtccaac

38521 aatgatagac tggattaaga aaatgtggca catatacagc atggaatact atgcagccat

38581 aaaaaaggat gagttcatgt cctttgtagg gacatggata aagctggaaa ccatcattct

38641 cagcaaacta ttgcaaggac aaaaaactaa acactgcagg ttctcactca taggtgggaa

38701 cagaacaatg agaacacatg gacacaggaa ggggaacatc acacacaggg gtctgttgtg

38761 gggtgggagg aggagggagg gatagcatta ggagatatac ctaatgttaa atgacgagtt

38821 aatgggtgca gcacaccaac atggcacatg tatatatatg taacacacct gcatgttgtg

38881 cacatgtacc ctaaaactta aagtataata ataataataa tacattcctt tttttaggat

38941 ttagtttctc atgccactta aattttattt ttcatattat tcagctgaat tttttggtag

39001 ttccttactt gatctgtggt tttctaacaa tggcagggtg caagctagtt acaattatat

39061 ttaaacaaac aaaactgtat attttatcta attcctgatt gtcagtagat tctggaaaga

39121 gcactgttgc aaccaagaac ttcactgaca tattgtccta tgtgtttcat ttgctaagga

39181 tcttccacca taaaaaaaaa aaaagttagt ttttgtagat atcataccaa agtgtattag

39241 ttccactgtt ttttgttttg tttctttcct ccaaaactct tacacttcct ccaacagcaa

39301 gaagtataag aacttaggag gaaagaaata tcttccttat gcttatgaaa agaaaggtcc 39361 agagtcattc ttactcttgt atgccttttt acctaggtag cttgtaaaag cctgtctttg 39421 caatgaagat taaacacttc ataagtttaa atatctaagc ttgtcatttc agggcttccc 39481 atggatgata ctctgggaat ctcctaaaaa cccatcttga gaaatgttaa ctaaataaaa 39541 aaatatgata tagaaaccac aatcaaagaa atgaagacat gtacaaatgt atctttccca 39601 ttgttatatg cagcttggat ttcctggtgc cttttcaata ttctttcatt tttttagact 39661 tttttttttt ggctttgggc attttaattt ggttgtgcta tgttcctcta tcttccgcat 39721 caatgagtct ttgctctgag gtatcaattc tgctctttac agcctccacc gaaagtttta 39781 cagcttctct gttgaattca caagtttaac aattttctga aatggattta tcttacattt 39841 gtaaagtcgt tctttcagat tctgtcactt tcagtgcagt taaatcaacc ttatcatgcc 39901 agcttcaggt ggcactgctt ctatgttctt gccgccttgc ctgtcctctc ccataaagta 39961 acatttttaa gtttgacttg agatttggtt ttgtttttcg tatttctgct ctttaaagct 40021 tatctcactg gggaacaatg agcatttcag aggctttgtt ttgttgctat tgctgaattt 40081 tgtttacatg agggtccttg tggagttatt aaaggcactt agacattcaa taatctttta 40141 aataagatta tcctcatttt tcctttcaac tctgtttttc caactcttgt acacttaccg 40201 ttctgatttt ttaaaagtct ctcttaccta cctcttaagt ctattcctga ataagataaa 40261 agtgtctgca acatctttta ttccattagg gttaatttgg ctggtctgag ttctaaatag 40321 attctacata gatttctcgt gaagacacat ttctcaggtt gtttgaaaac tgattatttg 40381 cagggtggtg ctaaattatc accccacaat cacttgctgg ccacaaggaa gaaaaccacc 40441 tttgcaaaca aagaaccagg ccatcaccat ccaacccact gatggccttc agcatcacca 40501 gatgtggggc agccaggtat taagagactt ccaatgcaaa gcactatgaa gcttagttgc 40561 atcacctata aaatatcctt cccaaaattt aatctctatt tacaggtata tatagaaaca 40621 agttagaaat accacgaaga agcaatcaag ttaatccaga atctacaatg tgggattata 40681 tgtactcacc aattcaatga caagttttaa aacaaacaaa acaaaaggga ggggggtact 40741 gtcctaaagt caaaaggact ttagggacgt aaggaccaaa tgcaatgtgt ggatcatgaa 40801 gtatcctaat ttaaacaggc caactgtaac actgctgaga tacagaaatc tgatgtagac 40861 agaatattta attttaagga attactatga gtttccttag gcatgataat gttatgatta 40921 tggaagaaaa tgatactact ttctgaaatg catactaaag ttgatggagt tcaggacata 40981 tcattccaaa ataagactcc aggagaccag actatgccac cccaaatatg cctctttagc 41041 ataagagtta ttttctacta attattttgg gcaatagcag acatagggga agttctgaaa 41101 acaggaagaa gaagttaccg ttttctcaga gaaatatgta tctacgaagg aaatctctaa 41161 tttgcaagta tgtctccctc tctgtaccag aaagagaagg atgactctaa atcactggaa 41221 actcttatca acaaagaagg tacaatctac ataacaaacc ttacccttgc tcactgcttt 41281 tcctgaccac ctctctacaa cgtggcggct ttccctgcac ctttctgtct tagtttcagt 41341 tgaagatggt atttacacct gaactcaaag ccacctcttg gagaattatt cattccatgg 41401 gtatctccca ggtatacagg aagtatacat gttaaaaagc ttccatttcc ctcttgttaa 41461 tctgtctttt aatacagggg ttcatctcaa ctaagaacta tgaagcatag agagaaaatt 41521 attttctcct cccctataag gccctgatat ctgggcttta tatcaaaata cttctgagaa 41581 aaacagagat gggacagatg aagcaagtgt ataaaaggat tatactgttc aatatcagtg 41641 ggtgaaaaat aggggctcat taagctattc aaattattct ctatcttgac atgtatttta 41701 aacatttata ataatggtaa aactaaaagt taaaaaaaaa aaacaacttt ttccattgtc 41761 ttccattctc ctctaccatt tttgcattcc tataacttca cccttgattt tacaactgtt 41821 tttagttcta aatggctcat gagaggttta aattttaaat atttctcctg gaaaatgaaa 41881 ctagtccctt tactaccacc tctatttcca actctctccc ttaatttcta aaagcaagca 41941 tatactttta agaaggccta aggagttagg tgtcaatggc cctaatccaa agactcacta 42001 tgcaatagat ttaacagaaa ttagagagaa tagtgggtaa ctactttaaa agacagaaaa 42061 gaaatacaac aaggataatg cctatatggc tacttattaa cagaacaaaa actctataaa 42121 ggaaatctct aagacatttc agcattcctt cttgcctata taactatgtt tcttgaattc 42181 tcttttgaac tagttgtaac atattacagt ttccctcatt aatgagttaa ataaaatctc 42241 agagatgtgt tcattttata tttgaatgat tcatgatttc atcttttaaa aaaattattc 42301 tttaattcat ttcatttcct ttcacaaaca ctgcaatgga aattggattc tgactagttt 42361 ttgaagtgtt ctaaagtaaa taagtataaa taactgacgt aaataattta aagtaaatac 42421 aaaaaattaa aaattaaggc caccttgaca taggacaatt atcctctgga atgataaaat 42481 aattagaaaa ggttttcaaa caaacctata aaaacatttt ataatcaacc attcctaaaa 42541 tatgaacatg ataaaatcct accatttgta acagtatgga taaatctgga ggacattatg 42601 ctaagtgaaa taagccaggt acagaaagaa aaatactata cagtctcact tatatatgga 42661 atctaaaaaa gtccaactca gagaaattgt gagtagaata atgattacca caggctgggg 42721 atcggggagt aggaatcagg aggtgttggt caaaaagtat gaagttttgc cagccagggc 42781 aacacagcaa gaccacatct ctacaaaaaa aaaaaaaaaa aaaaaaaggc caggcattgt 42841 ggtacattcc tatagtccta gctactctgg aggctgaagt gggaaaattg ctttagccca 42901 ggacttcaaa gctgcagtga actatgattc caccactgca ctccagccta gggaacaaag 42961 ccagactata gatagataga tagatagata gatagataaa tagatagata gatagatatt 43021 aaaaagtata aactttcagt caggaaaagt agcttctgga gatctactac acagcattgt 43081 tactacagtt aataaaaatg tactgtatat ttgaaaattg ctaagagaat agattttaaa 43141 cattcttgcc acaaaaagta agtatgtgag gtgattaata tcttagttgg tttgatttaa 43201 ccattacaca atgtatacag atattgaaac atcatgctgg actccataaa tatataaaaa 43261 attttaaaaa ttagttaaag taaataaaaa ataaacactt gtattgaaaa aaaaactggc 43321 tatatttatt cccagtaaca actaaagtat ttatgaaaca actgctaata cacatcagta

43381 ttctgacagg tattacatat caagtaaaac atcaactact tattcacaaa aagtaaaagt

43441 aagtttaaaa aaagaagaaa aaaatggaca aaaattaatg ccagagagtc ttcacgactg

43501 gattaaaagc ttcctttgaa aacagaaagc aagacatttc aagagggaaa aaaatcacct

43561 ctatttttag catgtttttc taaaatatca ttactttccc ctttcccctc aaaagcaatt

43621 ttttctaata gcccattcat ttcagcctca agtagataca catcacatgc accataatat

43681 tttttttaag ggtttagaca atgttactgt caggcttcct ggctttatat gattcagaag

43741 ccaattcaat tacagcagct gctatgatat ttgccttttc ctcaacactc tctatgtcag

43801 acaaaatgaa attctgtaag gtgaacagtg tatgtttgtg tacactggcc aacaacgaca

43861 tttcacttca atgttaaaca ctcatgtttt ctgctcatga gatgtataat attaatgatt

43921 tattcattta ctttgtccaa ttataaacgt gtaagaatga tttacacgag ttcaaacccc

43981 tagcttcctg aaagtataaa ggattcaaaa taaaatgaga ttaatatgaa tgcagccacc

44041 aagtgattct gatatctaaa aattgaatga agtgaatttg ataaagattt ttttaagttt

44101 ctgaataaag ccagtattga aagctctaaa aacatttaaa aatatatcct attcaaatta

44161 tgactataaa cataaccata aacaatgagt aagttcaaat taaatatttt tcctatacat

44221 tctatcattc tccataccct tcacccaaca aagaggggat ggtggagaga aacagggttg

44281 gtaagtgaag tggagaataa gaaattcagt ctaaatgttt tcagttttaa aataaatctt

44341 tgaagcagat ttctcttatt cacatctatt catattttat aacaatcttc atagaaaaaa

44401 gttaaataag gtgtctcttt caacgacaaa ttataatata cataaagtct gaacagtgta

44461 actataattt taaaactgtc atactattaa acatcaacaa attgatacaa catctgctct

44521 tcattttttc acccaagttg ttatgataac caaaatatgt ggaatatgtg tttaactgat

44581 tatttcaagt aaatagaatt ataacatatc agcttattaa ctacaagtaa tattgctaca

44641 aacctgtatt tatccttttt aaatgctaat ggatcacaag attatattta ggcaatttat

44701 acatgtttta tcttgaaatt cacatttaaa aaagcaaagg tttgcttttt tttctaatgt

44761 gatgggttat cttgacttaa agcaagaaag gaactcatct attttctgaa caatatatta

44821 tgctaaaatg atccaaaatt atattatggt actgttttgc aggagctgta gatcacatca

44881 ttttcaaaca taagtgacct tgtcactcct ccagtcctct gctcaaatcc ctccactatt

44941 gtcccatctc tgtgaacaaa agccaaagtc cttacagggg cgataaggcc cacgccctcc

45001 cccttccctt gctcacccca ttccacccac actggttttc ttcttgttgc tcctgcccca

45061 cagccttgta ctcttcccca agacagccac aagcctggtt ccttcactta tttcaaatct

45121 gtgttcaagt gtcagcttct caatgaaacc ttctttgact gctgaaggac cccattttac

45181 actgctattc ctgcacccct cccatctctg ctcacacata actgtgtgct aaggactcat

45241 gtgttcctct aaaattcata ttttgaagtc ccaacctcca gtgtaactgt atttggaaat

45301 aaggcctaaa aggaggtaac taaggtttaa tgaggtctga agggtggggc cctgatcgaa

45361 taggattagt agctttataa aaagagacat aagagagctg cctctccctc ctcactgccc

45421 cccactcccg cccccagcac caaatttatt atctgtctcc ctttactgca gaataagctt

45481 catgaggaca gggatttttg tctatttatt tcacatcacc tacaacctgg catataacag

45541 atgactgata aatacttgtt gaatgcataa agtgtaaatt taaaacattt taaaagttga

45601 taagctacag taagaaacaa tacatttttg tgatgatatg caagggatcc aataagaaat

45661 aaaaatatac aatcttcaat aagctaaagt ttaaaaatca aaatgatcaa aatttgtgtt

45721 ctaatcacag acccacagaa tcctgctttc ttggtttccY atttgctttc ttgatttcct

45781 atgaatctga tccaacacag gctctgtctt cctcccaccc attaaatgtg gaaaatatgc

45841 aatactgtta ctttgatctt tttctctaat cacttcctac gtgaactcat ccattctcat

45901 tgcttcaact atcacttctt tttagatgac tctgaaactc tgaaatcttc atctctggcc

45961 tggatttgtc tgtgctctct agtgctgtat tctcaactgc ctttgagggg aacataactt

46021 caccatactg ctagagatgt caaaggacag gaaccttagg tagaacataa catactcact

46081 agagcatgct acataaaata taatttcaaa atgtagtagt agtatacaga ctcacataat

46141 tctatatact gcctgagaaa ctgccttctt tcattatatg tcagaaatta gactacaata

46201 atagggaatt ccaatctttg agttatgact gtatattcta attaacaata tacccttgta

46261 ctatcagttt cacttcaacc actgagttat tcccaatatt gcaatagagt tttattactt

46321 tcaaattgaa tttaatcact tggggtgggg aatataagaa attatatgag gttttcaaat

46381 taagtttctg aactaggata gtttattttt agaagaaaaa tgtctcacgt ctttgtcttc

46441 atcatttgct cccaaataaa atttgtttct ctagccattt ttcttcctac tcactaatca

46501 attcattatt attttaaaga catctctaaa gcacagtttt tacctctccg aagatgctca

46561 gtaatttgat gatgaaatga caactcagaa tttaggagtc ttcacatgaa aagttggcta

46621 acagaattta ttatccaatt aaacaaacca catattttta gaatttcatt gagcgaaaat

46681 aaaaagaaaa aaaattcaag agaaaatcat attgttatca ttgctttaga gacaggccca

46741 ggcctcccag ggtgcgataa agtcccaggg gccttggata gcacaaagga ccctcttata

46801 gtcagtgatc ctcagtacaa gtcagttact gaagaaatac ataatgtccc atgcctatac

46861 taccctttta agaggaataa ttactacata ttatatcagg taaatttcac tgctatttct

46921 ttctcaaatt tttttttcaa attaagaata caaatgaaat ctagttaaga tagctgctga

46981 tatagagtga atgtctgtgt cctgtcaaaa tttatatgtt gaaattccaa ctcccaatgt

47041 gatggtatca ggaggtaagc gcctttggga ggcgattgtc ataagggtgg agccctcatg

47101 aatgggttag caccctttta taaaagaggc ttttgagagc tcccttgccc cttctaccat

47161 gtgaggttac aaggagaaga tggctgttta tgagctggga agtgggccct caccagacac

47221 caaatctgtt ggaaattgga tctaagattt cacagccttc caaactgtga gaagtaagtt 47281 tctgttgttt ataagccacc cagtctatgg tatttttatt attgcaacct gaacaaacta

47341 aaataggtgt taagaagcca tgcttggctg tcctcaatgc tcacaaaagg cacgaagtat

47401 gcctaaatta ccaacaaatc ctgtcatcac tcctttcaaa atatatccag aatctgactg

47461 attctttccc cattttctgc taccagatat cttggtccaa gccaccatca tctcctacca

47521 ggattatgag agtctcctaa aaagtctccc tgactccacc gttgccccac tagtctactc

47581 cacacaataa tgccagtgat cacaataaaa catgagtcaa atcaagtcac tcctctgctc

47641 aatatcctca actagcttct cctatcactt gaagtgaaag tcaagtcctt acaatggctt

47701 agaagatcct gcgtggtctg gtcccctttc acctcatctt gaactgttct tcccttccct

47761 tactccattc agccccaatg tcttccttgc tattccttga acacatcaaa catacgctga

47821 ctttaggttc tctgcatcag ctgcttcctc agcctaaaag gctctctctc cctccacaca

47881 gctaaaggac ttgctcccgt gcttccttcc ggattctgat tagtgaggcc ttccttgaca

47941 accgaacata gactagtacc ccttctctgc tgcccacccc tctctaatac ctttaatctg

48001 ctttattttt tcccaaggta cttattattg cttggcatac tatatgtttg tttcttattt

48061 gcattaccta actagaatgt taactccaag aaaacagact gttttgttcc ttgctcattc

48121 cccagcaata gaacacagaa tagtagatta atcaataagt atcaataaat atcgatctac

48181 ctaatgaatg aataaatctt gcactagagt ttcttatccc aaactagaag cagattcatc

48241 ttccttcaaa ctgcataccg tttttatttt tcttatgata aatcatatcc ttgtactaat

48301 aatcattttt tatttatctt agcatcctgt aaatatcaag aaccatatct tattcctctt

48361 tgtatccccc acatctagca tcatttcttt cttttaagag gtactccgta tttgttgggc

48421 tgaatttgaa gtcatactga aagatacttc tttttttttt ttgagacaga gtctcaccct

48481 gtcgctgact agagtgcagt ggcacgatct cggctcacta caacttctgc ctccagggtt

48541 caagcgattc ccctgcctca atctcccgag tagctgggat tacaggcgca tgccaccacg

48601 cccgcctaat tttgtatttt cagtagagac agggtttcac cccgttggcc aggctggtct

48661 cgaactcctg acctcaggtg atccacccac ctcagcctcc caaaatgctg ggataacagg

48721 catgagaaag atacttctat aatacacctg gatctgttgt gctatgcctt agcacatggc

48781 ccagtaccaa ttcttaaatt gctaaaaaat gttccgcttt cataacaagc caccaaattt

48841 aatacaagtg agatagaaga gagcgtgtaa cgtggctcag agatgcctaa catccatttt

48901 gtcctgatat_^ ggaaaccata aaaacattct gaatgatgtc aacaaatcaa aagattttca

48961 gaggatactg aaaactactt ggcagaaagc cgcctcagct tgacccactt atgaattcta

49021 cagaaagaaa agccagagag caaatgcttc actcttatct tcataaagaa ataaataacc

49081 agaaacaaac atgaagattt tttttcctaa aaaaacaaat tccagtacca ctactacaat

49141 taatatccac ttgacccaaa acttctgtac aactcattaa ctggtatttt taacaaaaag

49201 cttaaatcac caaggaaaga ttaaattatc atcaacatgt ttaaaaaact taatatgcct

49261 tgagttttaa actttcatca agtcagttaa aattaaagtc tcatactaaa ggagttaaac

49321 cttcactatt aagaaaagtc aactgtacat agtaatttat tctccaagac ttgtggacaa

49381 gcagaatttt gcttttcagt caaattctgt gacaactgat aatccataat tatagtaatc

49441 aaaatagtta ataggctaga actctctttt actaagcaaa agaagtgaca gcattaaaaa

49501 taaatgatac agtaaaaata atgtcccgcc ttctacggtg tcagctcacc tgaggtataa

49561 gtctatccaa gtactcaact cgattgccat gagaagggtg tgtagataac cattctggca

49621 tcttgggttg gccatgcagR ctatcaacRa actccatttg ctgccaaaac actgaactgg

49681 ctcttatgtc tgcacaagcc taaaaccaaa attagtaaaa ccacacaatg agctcagttt

49741 tgaggatttt ttaaaaacta ctactttatt tttttttaat tctattataa ttatacttta

49801 agttttaggg tacatgtgca caacgtgcag gtttgttaca tacgtataca tgtgccatgt

49861 tggtgtgctg tacccattaa ctcgtcattt agcattagtt atatctccta acaactttat

49921 gtcactacat gctttaaagt cattttctat catcacttta ataaaagtag aacatgccca

49981 ttgcttagaa aaagacccac ctcaaacaac atggtatcac agtactgaaa taacagaatg

50041 cctgcccttc ccatatacaa cattcacaat aaccctgcta accaaagata gcccactatt

50101 ttcagtatga tggatattaa gaacatgtat taagggtaaa atcttttaca caaattaaaa

50161 attctgtttt cataaagttt taaaatataa tgttattaaa ctgtattaaa gaaactttac

50221 ttctatgcca ctagaacaat cagaaaaaaa cttcaaataa acataaagag atgacatgtt

50281 tattatgcac atcaatttac ccaattttct caatgtatat ggacaatata tttaattcat

50341 ataccttata aaacacaata ccttataaaa gtacaatata aaagtacatt agtacttttt

50401 aaaagaaYat atgtagatct tgtgtatgta caattccatc atacactcat atacatactc

50461 atacgtatat acttgtatat gcacagaaca tatctgagaa gctatttaag aagctgttaa

50521 ctaccctaag aatgtacctg aggtatctga tagtggagag ggagcaacac ttttatttct

50581 gaactatatt aaaatacatt attttataat taaaattatt tttaaatcct ccataaggtg

50641 gattattaac aaatatttta ttaatttgtt caatttattc acatttctta acttattctt

50701 tctataataa gtaactggaa aacaagtggt tatatttccc aatgatttta tttttgatta

50761 aaactaagaa aaaatatata tactatactg actaaaatgt actctcaaaa agatttataa

50821 tagtgtaatt gtgaaacccc aaaaggcaaa tatattaata gaacactgca tgctagtcaa

50881 caaccatgct acatcatttc ttaacaaata ccattaaagc atttccaaat gttagcaaaa

50941 taaaaaattt taaattcaag taaatcttat tcaatattta aagaaatata attccttaag

51001 acctctgagt attctaagtt gaaaagaatt caaggtactt tatacactac tgcacagata

51061 tggatataca tgtttatatg tatataaaca ggaatataca agataaatgt atataacaaa

51121 cataaatatt attcatgttt atacacatat aaatacatat ctatatatgc aagatgtgtg

51181 tgtgcttatg tgtaaaatat gtatgtaaca tatgtatcta taaagaaata attatttgat 51241 gctgaattag aaacacccag aggactatgc ccctcaataa taggtaatca cattcacaat 51301 aaaaatacag gctgagatta acaagtattc ttctcaaata attcataaaa atataaaatg 51361 acttgaaaga attctaacac aaacaaaaaa cccctctgaa aactggaaga taaacatttg 51421 aatggactac aaattcacga attatctaac atgaagtttg tctgctacac aaaccaaagg 51481 catacttatc taattttttt agcctaaaac tgttaatcaa aagacaaaat atttccctat 51541 tcaatctcta agtaacacag ctgaagggaa tctttaaagc aatatttgat atgcagaaat 51601 agaaaaagaa attaattatc cctacagact agaaagtatt ccaagctaaa agtattaaaa 51661 ggggacttga gatatctact ttaatgttaa gataagagtg ttgagtttgt ctgtacttct 51721 caaacccagt tcaaagagcc actaaagtca gataattttg tttccaaaat gagtatttta 51781 tttacatttt tccaatttag gaaaaataag taacaggttg acatcagcaa gatggaagaa 51841 taggacgccc taaaccctcc ttccccacat gaacacactg attcaacgat aatatacgaa 51901 ttccctttgt gagaaatcct gaaactaggt gcaatgcttc tgcacctgca caagtacgaa 51961 atgaacaaca tcaaacctgg tagaagactg gagacaccct cttgccataa tctgcgagag 52021 caattatgta cccccaatac agcaccatat gatcataaga acacctgcag ctccccacca 52081 ctccttgggg aaggaaaaac ttggcttgtg tatctaacat tccaactttt ctaagagctg 52141 ccctaggaac tggcttctgt cttgccagcc ttgtagcact gatggaatct aaaacgccct 52201 agatatctag gggccagtga taatgtgaca gaagtttgaa caagcacaca agcagttgcc 52261 atgaccactc cctgaagctc agcatgaaat gagttggaga gaaactccag agcccagctt 52321 ctcctggggc agggctcggg aaagaggtag atcacgtgtc caacattcta acatttctga 52381 gggctgtcca agggactggc ttctgtctca tctgtcttgt agcactgata ggacccagca 52441 tatggaccag atggaccaga caggacccta gacacctagg caccactaag aacaaagaca 52501 gcactttgga ctagcatgaa ggtttgagag gttctgggaa tctctgctgt gctgactggt 52561 gaagatcttc tcctgtacaa agacagtctg taaaggctaa gaggttgctg ttttttccta 52621 atgtgtagat atcaacaata agagtgaaaa aaataaacag agaaatatgt accaaaggat 52681 gaagataaat cttcagaaac tgaccctaat gaaagagaaa tatattactt atctaacaag 52741 agaattcaaa ataaccatca taaagacact caaagaggtc agaacaatgt acgaacaaag 52801 tgagaatttc aacaaagaca cagaaaatgt aaaaaagtac taaacagaaa ttctgaagca 52861 cactcctaaa caacatactc ctgaacagcc tatgggtcaa ggaaaaaaaa accaaaaaga 52921 aaatgatttt gagacaaatg aaaatgaaaa cacaatataa caaaactgat gggatacagc 52981 aaaggcagtt ctaagaggat ggtttataat gataaacacc tacattaaaa aaaaaaagaa 53041 gaaagcaagc aaataaacta actttatacc tgtaagatct accaaaaaag aaaaaaaaaa 53101 aaggactaag cccaaagttt acagaaggag ggaaataata aagattagag cataaataaa 53161 gaaaacagag aataaaaaaa tagaaaaaaa ttaaaactaa gagctttttg gggaaagatt 53221 tacaaaactg acaagtcgtt agagtaagaa aaaaaaagac ttaagtgaac aaaatcagaa 53281 acaaaagagg acacattaca gcataccatt gtaactgata ccatacaaag gatcataaga 53341 gactactctg aacaattata tgcccacaaa ctggataacc tagaagaaat ggataaactc 53401 caagaaatat acaacccact aagactgaaa aagaaatagg aaatatgaac aaatctataa 53461 ctaatgagat tgagtcaatt ataaaaaacc tcccaacaaa gaaaagccca gaaccagatg 53521 acctcactgg tgaatgccac caaaaacatt taaagaatta atgtcaatga ctctcaaagt 53581 cttccaaaaa attgaggagg agaaaacact tccaaactca ttttatgagg ccagccatta 53641 ccctgatacc tatgccaaag acactacaaa aaaaaattac gggccaatat ccctgatgaa 53701 cataaataca aaaattctta acaaaatact agcaagccaa attcaagatc atattaaaag 53761 gatcacacct catgaccaag gaggatttct tcctggtaat caagaatggt tcaacacaca 53821 aaaatcaatt aatgtgatat accacattaa cagaataaaa aaacacatga tcatctcaat 53881 agatgcagaa aaagcacttg acaaaattaa acatcctttc ataataaaaa ctctcaaaca 53941 ctagaaatag aaaaaaatta tctcgacata attatagcta tatatgaaaa gcccacaact 54001 agcatcacac ttcatggtga aaaacaaaaa ttttttcctc taagtctagg aacaaggcaa 54061 gaatgaccaa tcttgccact tctcttcaat acagcactgg gagtcctagc cagggcaatg 54121 aggcaagaga aagaaataaa aggcatttaa atcagaaaga aagaagtaaa atgatttgca 54181 gatgatatga tcttataagt agaaaactaa agactccaca cacacaaaaa aaaaccctgc 54241 tagaactaat aaataaattc agtaaagtta gtatacaaaa atcagcatac aaaagtcagt 54301 tatgttctac acactaacaa caaactatcc aaacaggaaa ttaagaaaca attccactta 54361 caggaaaatt aaaaagaata aaatacttat taaaccaaac taaggaggtg aaagccttct 54421 acactaaaaa gtatctaaaa aaaaactgat gaaagaaatt aaagacaact caaataaatg 54481 gaaagacatc ccatgttcat ggattgtaag acttaatatc gttaaaatat ccataccacc 54541 caaggtgatc tacagattca atgagatctc tatgaaaatc ccattggcac ttttcttata 54601 gaaacagaaa aaacgatcct aaaattcaca tggaaccaca actaacccca aatcgccaaa 54661 gcaatcttga aaaagagtaa gactagaggc atcatgcttc ctgatttcaa aatatattac 54721 aaagctacag taattaaaac agtatagtat tagcagaaag ataaccgtta aatgaatgga 54781 acagaagaga gagcccaaaa ttaagcccac acaaatacag atctttgatg agggtaccaa 54841 aaatatacaa tgggaggcca ggtatggtgg ttcatatctg tgatcccagc agtttgggag 54901 gctgaggcac atggattgct tgagaccagg agtccaagac caacctgggc aacatggtga 54961 aaccatctct acaaaaaatt aggcaggtgt gatggtacac acctgtgcac caagaggctg 55021 aggtgggagg atcacctgag cctgggaagt cgaggctaga gtaagctgtg atcacatcac 55081 tgcactctag cctgggtaac agagcaagac cctgtctcaa aaacgaacac acacacacac 55141 acaaacccca caatgaggaa agagcagtct cttcaacaaa tggtgctaga aaaactgaat 55201 attcacatgc aaaagaatga aactggaccc ttatcttacg ctacacacaa aaaccaacta 55261 aaaatggatt aaagatttaa acgtaagacc taaaactata aaactcctag aagaaaatat 55321 aagggaaaag tttcatgact ttggtcttgg caatgatttt gtgaatatga caccaaaagc 55381 acgggaaaca aaaggcaaaa atagacaggt ggaactacca aaaagctctg cacagctaag 55441 gaaacagagt gaaaggcaat ctacagaatg ggaaaaacca tttgtatacc aaataactga 55501 taaacagtta atttctaaaa tatataaaga atttctacaa ctcaatagca aaaaacccaa 55561 tttaaaaaat aggcaaagga tctcaataga catttcttca aaaaagacat tcaaaagtag 55621 gtaacaagta ttagaaaaaa tgttcaatat cactaatcat cagggcaatg caaactggaa 55681 tcacaatgaa atattacctt acacctgtta ggttatctat cattgaaaaa aagagacatc 55741 taagtgttgg caaggatgtg aagaaactgg aactcttgta cactgtcagt gagaacataa 55801 aatggtgtgg actttatgaa aaacaatatg aagattactc aaaaaatttt taaaaagtac 55861 tatcattatg attcagaaat cctacttctg gatatttatc caagagttga aatcaggatc 55921 tcaaagggat ttgcactcca cattcattgc agcattattc acaatagcca agatgtggaa 55981 acaacctgaa tgttcatcag cgaatgaaca gattaagaaa atgtggtata aacatacatc 56041 aaaatattat ttggccttaa aaaaggaaat cctgtcatat gcaacaatac ggataaacct 56101 tgaggacatt aagctaagtg aaataagcca gtcacaaatg gacaaatacg agacgattcc 56161 acttacatgt ggtatgtatc taaagtagca agcttgtaga agtagagaat agaatagtgt 56221 ttgtcaggga gtggaagtag gaggaaatga ggagttgcta ttcaatggat ataaagtctc 56281 agttctgcaa aatgaataag atctagagat ctgatataca gcatgtgcct atagttaagt 56341 atgtgttgta aaattataaa tttaagaggg tagatctcat gttaaatgta cttactaaaa 56401 aagagaaaaa aagtaacgat agaccaaaat aaaggcattt ttaaaataaa tactcagttt 56461 atcacaagtc taattctttt gcttcaagaa aagtattata gaaaactaag aacttattaa 56521 gcaactgata tggtttggct gtgtccccac ccaaatctcg tcaacaactg tcatccaaac 56581 tgtaatcccc atgtgtcgag ggagggactt ggtaggaggt gactggatca tgacagcagt 56641 tcccccatgc tgttctcgtg atactgagtg agttctcatg ggatctgatg gttttaaaag 56701 gcagttttcc ctgctcttac acactcttcc tctcttctgc tatgtaagac atacctgctt 56761 ccccttccac catgattata agtttcctga ggcctcccca gccatggaga actgtgagtc 56821 aattaaacct ctttccttta taaattaccc agtcttgggt atttctttac agcactgtga 56881 aaatggacta atacagcaac taattcagtc taactcattg cttcaataaa attattgaac 56941 tgaactaaat aacttattaa gcaactgtaa gtacacgaag aaagaattag actctaggta 57001 acctttcctt cttaaaaaca gaactaataa tggctaccgc tggccagaga aacataagaa 57061 aatatgtgtc agtgaaatac tttggtccta gaatattttt tgagactgta aactaagata 57121 atggagagac tacaggtttt agaatcagaa atatctgggt tcaaaatact gattatttta 57181 tttattaaca gtcacttata tgacaccaca tgccaggcat tgttttaagt gtattacaaa 57241 tattaacaca ttatattaac tcatttaatc ctcataacaa cttcatgtgg taagtactgt 57301 tatgaccctc actttacaga ttagatgaag aaaccaagat ccatggtgac tacataactt 57361 gacaaagctc aaacagctag taagtgacag agccataatt tgaacacaag tagtctggtg 57421 acagagtttt tgcccctggg tcaataattt agtctctagg agtctcagat gcatctgtaa 57481 aactaaatta aagcagtgaa ttgtcaagtt aaaatgtgat aattcttgca aagcagccat 57541 tccaggactc agaacatagt ggacactatt tctaccttcc tttcccctgg tgagcaactg 57601 gaggcctatg gtaattgcaa aatgctatgt ttggtcctaa gtgatgatgt catgaattta 57661 caagaaggtt ctagtacaat ccagagaata taaatgtata tgaatatgca ttaaggaaca 57721 tattgagaaa gaatttgcta ctattaaatt ataaattcag tgggatatga tattcataaa 57781 gaatacagca gtataaaaat tgttcttata atttcaccat ttcccaatgc caaaacaata 57841 ctagagaaat atgtataaat agatctagac caagtaaaag cctaactgta ccgttacctg 57901 tagccaacgt tttcattaga aatgcaaaga tgaaaagtat ctctgaattt tgctgtctgt 57961 attcactaga cactccaaca aagctcctgt tagccatcac ccccttccaa aggtaaatcc 58021 tgacactgaa tgaatctgaa tcttttttta ggaaaccatt aacaccctac acttgtccca 58081 gtcattgtag catcctctcc tgtattccac atagacatgt gataggtaaa ataatcatct 58141 gagacaatac tacaaaggat tgtggcaggg ggagctgggc tcctacagct agaaaaatac 58201 actgaggctg ttataagatg taaagggacc aaaacagata taaaaatgat cattatttta 58261 gaagcaatac tgcagaaaac caaaattgtt tccagcaggc aaatataaga tggaaagttc 58321 cctttcagaa atgaatgtac ctccactttg ggagagggaa accttactgt ctatgagagc 58381 tttgccaagt tacttaactc ctccatccct caggtttacc tatacctcac agggttgtta 58441 tgaagatcaa aagaataaat acatgtaata cactcaggac agtgcccagc acattaaaaa 58501 tgttattgat tattatacac tacaatcatc attgtcatca tctaccagaa actagttcat 58561 ttcagtctca catacctcca caggttcatc attttccaat attgctgatg gcatcacttc 58621 ttaaagctca ttttattttg taacccactt attctctaaa caacattttt ccaggaaata 58681 atttaaaatt gctcttttcc aactaaatgc aacataatct tgagataatt tcagctaagc 58741 cattctcagc atttgccaat ccctcacacc aagagaaaac ttatcaaaaa tacttcatgt 58801 gctccaacat aaaaatgaaa gacatatgtt ggtcatttaa tcttaatttt ttgctcaatt 58861 ttctgcatct tttgattgcc agcaggtcat ttcaccaatc aatataataa attaagtttt 58921 aataaatttt catgttactt ttttccctct atcttaggta aagttttatc ataagactca 58981 acagctgaaa tcatagcaat gaaaaatcag atgaatacac acaagcctgt ctcatttttc 59041 tgggtgataa aattaagttc caaataatgt atgcattatg aaagttactt tacaacatac 59101 ctattaaata agatggtctc cttacttact gattcttttc tttcttaaaa gaatcattaa 59161 gcaaagaacc taaaacagta acccaaataa aacgcaaaga tactttgctg tgatgaaagc 59221 tcagaatact aacctgaaaa ataagaacta agggtcttcc tactaactag gtataggtta 59281 ttagataaat cactttacat ctttagactc tggttttctt atctgtaaaa tgagaaggta 59341 gattaaatta gctccaattt tctttcctgc tctaaaagtc tatgattcta caaggtacta 59401 ttttaaataa agtttagaat ttgaaatttt ctcatttctg tgatgaaaaa tagattttgc 59461 ttattaccta atgccctcac tagatggtgc tattggcaca gttatctcag gttacttgag 59521 gaaactagca ggccacgttt cccaaaaggg ccacttaaca ggctttgggg attactccca 59581 gtgagtgctt tccaggccac tataggatat ttattatccc .cttttccctc acattaaaca 59641 tcaataattc cccccacttc cccaataact atgacaatca aaaacaatca tacaccatgt 59701 catcctagaa ggctagccca gttcagaacc actaaaagaa tatcagtttt cttttccaaa 59761 cttaagaaac tgttacgaaa aaattaaaac tgatagttta gttgcttgtg aaatttttaa 59821 aaagtcattt ctataatgac tgcaaagtgt caaaagctct ttacagtgac aaatgaatat 59881 tcatacccca aaagatcaaa tacttaacag gacctctttt gtcagctgaa gactgaacag 59941 cttgttattc tatgcttaat ttacatgttg gtcttaccag tgattattaa ttctatatta 60001 atcattctga taatttatat aacgacaaat gccttccaaa tgaaaaatta aaagaactcc 60061 tataaaaaca taaatttgca caataaaatc actcatagcc agtagcagag gagcagcaga 60121 gaaccctagg gaaagtgggc tgcctacttt gaaagaggct tcatgagtaa catcgttttt 60181 gtgaattttg cacgttgaaa cctcataaat ccaatgggac tgcatatgac caatagaacc 60241 atctctcaga aatagttccc agtaaccaag ctcacaagat tgacataaaa tcagaatgcc 60301 aacttcttaa tttacagaga taactacagc tgcccaaacc agcaagagca catgcatcta 60361 tgtccttggg tcaggacttt ctctcccttt taggcatgct acagaggaag ccaggctgta 60421 atcagaaggt tgcctaggaa ggagagaatt aggaaaagga ggattatgtt gacatgattt 60481 gaatgctaca atggcaagaa gtcaagggag tctgatgcat caaggtccaa aaaaaggata 60541 caagccacaa ataagaatca agtccaggat acccaaaata actctttgat ggaagtacta 60601 tcatgattct cactagtcag actacaaaac agatttgaag aggttaagtg atttgctaca 60661 gtcatgtgga ggagacaaga gctcaaacac acatctggac tactgaaccc aaagtcctga 60721 cccctatgct agacaaggtg taaaatcctt aaaattgcta ataaagaagt ttctgcctat 60781 ccttcagttt tatctgttgc cattggtgct cttgaattct gttgacattt taaccacaac 60841 aaattttcaa ttcctggaat aagccattgt ttctcttgcc tttgaacaca ccatgccaaa 60901 cactacacct atcaacatct tcatcaggat aattactatt tatctttcag atctccattt 60961 tatctatttc tttctcagtc taatcccaag actaagtttt cctatgtaat ttgatgtaac 61021 ttgagagatc cctcaagtta catctctgct acattctccc atggaatgaa tgtttcctgt 61081 atctccaatt cataatactt caaactttgt taaaattatt tattaaattt ctgtctcttg 61141 aattctaatg tcatgaagat attatgtatc cctataatct ggaagttaat tacattcaat 61201 taataaatga aaatcatcat aatggatcag agaagagcta gcacctaggt ctgtaagatc 61261 aaactgtctt ctgattgtat taatgttaaa tgtcaatcca aagtagggga ttggtcaggt 61321 gagaaaggga aaagtctgga ggaaaattct ggtcaatgtc ttcttaaagc cttatcttaa 61381 gaaagtgagt atcaggccgg gcacagtggc tcacacctgt aatcccagca ctttaggagg 61441 ccaaagtggg tgggtcacct gaggttggga gttcgagacc agcctgccca acatggagaa 61501 accccgtctc aactaaaaat acaaaattag ctaggcatgg tggcacatgc ctgtaatccc 61561 agctactcag gaggctgagg caggagaatc gcttgaacac aggaggtggt ggttgctgtg 61621 agctgagatc gcgccattgc actccagcct gggcaacaaa agtgaaattc tgtcagaaag 61681 aaaagaggag aggggagagg ggagagggga gaggggagag gggagagggg agaggggaga 61741 ggggagaggg gagaggagag aggagaggag aagagaagag aagagaagag aagagaagag 61801 aagagaagag aagagaagag aagagaagag aagagaagag aagggaaggg aagagaagag 61861 aagggaagaa aagaaaagaa aaaagaaaag agaatatcat catagcttac tggatctgtt 61921 tcttacttgt ggcagggtgg agaatggaat ggaggggagt aggactggag tcaatgaaag 61981 ctatcatgag cctgctacag aagtttaggt aaaagatgct agtactggag atgggaacat 62041 actgagatat attttataga tagaactgcc aggacttggt gaaaaaatta agagtaaatg 62101 ataaagaacg aatatcttta tctataaacc ctggaggact ccagggtttt ttttccaaaa 62161 gcaactgaat agagggtagt atattcattg ggaaaaggga gaccagaaga aaaacacatg 62221 tagggagaaa ttaagaattt aatattgaac atactgggtt tgagataatg tatctgtgaa 62281 ataaagaaga ggagatagca gacagtcctt ttaagataaa tgattaaaag acacgagctc 62341 taagaatttt aattatatta agtgtatgag ataggtccaa tactgttcct atcctacaga 62401 tgagaaaagt tgaggcacaa aaaggataaa taacttgatc ataatcacac agctagtact 62461 ctctctggga aagcagattc tcaaacttgg cagtatRgtt ccagagttca tgcattatct 62521 ctacacttat tgctcgcttc tttggcaatt gattgattac cccacactgc agagacccca 62581 gaaaggttta gtatttgact tccaagaaag aaaggttgag gtataagggt cataacagag 62641 aatttttaaa agtctccaca atgaatggga aaaccctact cccttttcca ctgccaatcc 62701 tcaaacactg acaaaccagt ttacttgttt tttatttttg tgggcacttg gtaggttata 62761 tatttagggg ttacatgaga tattttgata gaggcatgaa atgtatagta atcacatcag 62821 ggtaaatggg gtacatccaa cagccagttt ttacaggatt catctgcaga cacgtgaatg 62881 accacagagg aaaggccaat atatattcta tgggaagctt ccccaaagaa agagctagat 62941 cgctgtccta caatcttaca gtagagctca tcatcccagc ctatgcaaac tcacctcagg 63001 ctctgaatga gtgaagagat ctgctatgct ctaagtgacc acttagcaca gagaatacct 63061 ctgatggaaa aaaaaaatat atcattcaga gccaacagaa ctgtttatat gaaacatcca 63121 gcattcaatc aaaaataagc aacgatgcca acaaacaaga ccaaagccaa aaacagacaa 63181 cagaaacgga cccagctata atacagagat tagagttaag aaacatgaat ttttaaaaaa 63241 atatatgatt aacatattca agaaaatata aacaaagaaa catatgacaa aatggagaat 63301 ttcaccagag aagtgaaatt tataaaagag catcaaaggg atattctgga atgaaaagac 63361 aaagtaactg aaatttaaaa ctcaaatacg aatttaatgt agaacaaata cagctaaaaa 63421 taagattaat gaacttcaag ataggtagtg gaaaacacat tctgatacat ggacagtcag 63481 aggttaagtg attagcctat tgcatgttct cactcataag ggggagctaa acattgacta 63541 cacatggaca caaagatggg aacaacagac actggcaact accagaggga agggggaagg 63601 aggggagcaa gggttgaaaa accacctttt gggtaccatg ctcactacct cggggagagg 63661 atcatttgta caccaaatct tagcaacgtg caatttaccc acgtaacaga cctgcacgtg 63721 taccctggaa cctaaacgtt gaaaaaaata aaaaataaaa gagcaagcca cagaatgaaa 63781 gaaaacactt gcaagacaca tatctgacaa agaacttgca cctagcactt atgtgaaaaa 63841 ctcctacaac tcaagaataa gaacacaaac ttccttgccc aatttgaaaa tgggaaaaat 63901 atctgagaag ataattcaca aaggaatata aatgaagtgc caatagacac ataaaaatgt 63961 tccacattat ataaataatt acaaataaga aatgcaaatt aaacaaatag actaactttt 64021 ccccaaaaaa gggcaaagat aaaaacaaca gcaatgttct gtttacaagg gctacacaca 64081 caagaacaca ggaggtttga aaatcagaat attaaagatt taccatgcaa gcactaactg 64141 aaagaaagct gaaataacaa tactaaaagg aaaaagtgga cattaggcaa gaagtattac 64201 tagagacagt gattttattg caagaaaagg accaatccac taggaaaatc taacaatcta 64261 acaagtatgt atattaaaga tacttttaag atgtacacgg caaaaattaa tagccctaaa 64321 aggaaaaaag aaaaatctac aaccataatg aaatattacc aaacctctct tgataactac 64381 aaaaaaaagg aaaaaaaatc agcaagaata tagaagatct gaaacaacaa aattgacaca 64441 cttggcaaaa ctgacatcca cagaacacca cccgcaatgg caggatccac tttcaagtgc 64501 acgtcatttt gacaaaattg atcacatcct gagccacaaa gcaagaccca acccttttca 64561 aaggattcca gtcattcagt atattatcca atcagagtgt aactaagcta gaaatcgaaa 64621 acaaaaggta actttaaaat catcaaatgt tcaaaaacta agcaatatac ttctaaataa 64681 cccatgggtc aaagaagaaa ccacagcgaa aacaagaata cattttaaac tgaagaaaaa 6474^1 ataacatatc aacccttgca acatgacaag taaagatgct ctcagaggaa aatgtacggc 64801 cttaaatgta tgtactagaa aaaaaaaaga gtttaaaata aatgatagta gtattcatct 64861 taa'gttaggg aaagaaccac atatgaaacc caaaaaatga atgcagaata aaataatgaa 64921 aaaaaatggt aactgacata acagaaaaca attatataat agagacaata agcaaaccca 64981 aaagatggtt ttgaaaagat tgatgaaagt gataaaatct agcaaaaaaa agacaagaca 65041 aagagcacca atattaacaa aggggacatt taaaagatac atgtaaaata acaggtatcc 65101 ttcagacatt aaaatataat aagagtatat taaaacaact tcatgccaat gattttgaaa 65161 attaaacaaa aattcctaga aaaactacaa aaactgaaac aagaaataga aaaatctgaa 65221 tagttctata tctattaaag agactgaatc cataattaaa gacaaactca tgaagaaatc- 65281 ttcaggccca tatggcttta cccaggaatt ctccaaacgt ttaaaaaata aatatagcta 65341 atcttacaaa aactcttctg gagaagagaa aatgaagaac acttccctga tcaattttat 65401 gaggccagca taactttgat tccaaaacct gacaggacat tacaagaaaa gaaaattcta 65461 ggcgactatc tcctttgaac ataggataaa cattctaaac taagcattaa accaattcta 65521 gcaatatatt aagggataat tgacaaaatt aggtatattt ccccaaaaat gcaacttaac 65581 tttaaaaaaa attaatgtaa tttgcccaat aacagattaa aggagaaaaa tcatataatc 65641 atctcaatac aggcagaaaa tgcaggggga aggagaacat caggaagaat agctaatgga 65701 tgctgggctt aatacctagg tgatgagttg atctgtgcag caaaccactg tgacacatat 65761 ttattaatgt aacaaacctg cacatctgca catgtaccct ggaactttaa agttgaagaa 65821 aaagtgcaga aaatgcattt gataaaattt aatatatata cataattttt ttaaatctta 65881 ggatattaga aatggaagag aaactctttc atttgataaa aaagtatcta taaaaagctt 65941 acaacaaaca tcataatggt gaaatactga atgctttctt gcccctaaga tcagggagat 66001 acaaagttgc ccatcaccaa ctttgtacta aagtttttgg ctattgcaat aaagcaaaaa 66061 ttaaaaagta cagttgaccc ttgaac'aaca tggaggttaa gggcactgac ccctctgtgc 66121 agtcaaaaat ccacatgtaa catttgactc ccccaaaacc taactactaa tagcctactg 66181 ttgaccttgc cagtaacaca gtaaattaac atgttttgta tgttatatgt attatatact 66241 gtattcttac aataaaataa gctagagaaa ggaaaatgtt attaagaaaa ccataaggaa 66301 gagaaaatat atttactatt cattaagtgg aagtggatca tcataaatgt ctccatcctt 66361 atcittcacac tgagtagact gagaaggaag aggagagttg gtcttgcagt tccaggggtg 66421 gcagaggtag aacgggagac aggaaaggca ggcataatca gtgtaactta atggagatac 66481 tttgtaattt ctgttgtaaa ataagtcaaa agtagtcttg aataatcaga atccttctgc 66541 tagattgtct aatgtcaatt tgttttctgg cactactatg tcttttctac ctggcaccat 66601 tttggaagca ctcatctcca tcaagtcatc cacggttaat tcccctgata aggtgtttct 66661 attagctctt gaatttctct aagatctgta tattgaaacc cttcactccc cacctttttt 66721 gccatatcca taatcttttc atcatttcct tgactggctc tgtgtggtca cgcacaacat 66781 ctggatagtt tgcttcatca acaatttatt atttcaggct tggtggcttt catggctttt 66841 tctataacaa tgatggaatc ttcagtggtg taaaccttac agactttcat aatgttctat 66901 cggggttctc ttcaatagca gtaacaacct ttccctaaag taccctgttg tactgagcct 66961 taaaggtcct tatggccctc tgatctgaga ctcaactagg aatgttgtgt ttgggggcaa 67021 gtagaccatt tggacgcctt cagtgttgaa ctcatggggt tccaggtgac cagaggaatt / 67081 gagaatgtaa aaagaactgg cagtcctggc cgggcgcagt ggctcacacc tgtaatccca 67141 gcactttggg aggccaagga gggcggatca cgaggtcagg agatcgagac catcctggct 67201 aacacggtga aaccccatct ctactaaaaa cacaaaaaat tagccgggca tggtggtggg 67261 tgcctgtaat tccagctact cgggaggctg aggcaggaga atggtgtgaa gctgggaggc 67321 agagcttgca gtgagccgag atcacaccac tgcactccag cctgggtgac agagcgagac 67381 tccatctcaa aaaaagaaaa aaagaactgg cagcctttac tggcaagata attcttaact 67441 ttaggaacaa agcatggatg gaaccaatcc agaaaaagcg ttctcattgt gtagcaggcc 67501 tttttgcttt acaaccaaaa gactggcagc tggtattatc tttttcctta gaggctcagg 67561 ggttaccagc tttatagata aggaaagtac ttacaaatcc aactccattt ccgcaaaaca 67621 gtagagttag catatccctt ctgccttaaa tcttgatgct cattaataaa tgtcctttat 67681 ggcattatct tttttccaga atagcacact ttcatctgca ttaaaaacct gttccggcag 67741 ctattctttc tccttaacga ttttcttaaa gcatctggga atgcatctgc tgcctcttgg 67801 tcagcagaag ctgcttctcc tgttatcttg acatttttaa gccaaatctc taaaactatc 67861 aaaccatcct tcgctggcat taaattctcc agctttagat ctttcatctt ccttttaagt 67921 tgtaatataa tgactttgct ttttcttgaa tcatattaga gtctatagat aggcctttct 67981 tatggcaatc ctgcacccac ataaaaggtg catcttctat acaagataaa agtcttttgc 68041 aaaaagtgca aggttttcat gcttgctggt agagttgcag ctatgacttc acaaattttc 68101 ttttcctttt ttcaacggtc cttattctgg attcgtttat gttgaaatgg caggcaacca 68161 cagctgcaga cctcaatcta cagtatatat caagcaactc aactttttct tgtaatatca 68221 tgagtttact tcctgggaac atttccagta tcactagcag caactcatat gggtctcatg 68281 gtattactca aggtgtttac agtattgcac taaacacaat gaaaaatatg caagaactgc 68341 aagagaccat ttactaagat actcaattta ctggagagaa agctgctcac atggagatga 68401 ttagtgtctt ctggtgtttt aagtagatat tcacaatatt tgagatcact gcattagcaa 68461 caggaagtga atacaaaact ataagagtag taccataggt accacagtta attctatgca 68521 gttatgattt aatactgcat ctttctgttt gtttacattt ctctcaactg caaatggcac 68581 catgtatggt ctgtgtaggc acacgttttg ataaattttc ataaccgatt tgtgttttat 68641 ggtaaaaaat tataaaagac taatatctac atgtatttta tgcattcatg acatatcctt 68701 ttcttaattt tttcaatatt tctaagctac atggttcacc tgtgagtttt ttcaaattgt 68761 tgcacatttc caaaaaacct tccaatatat ttattgaaaa aaatcctatg tataagtgga 68821 tctacacagc tcaaaaacat gctgttcaag agtcaactgt atacagattg gaaaggaaga 68881 aataaaggtt gctgggtaca aggtcaatta taaaatcaat tgtattttta tatacaagca 68941 atttacttta aaaatgacac tatttatcat gacatcaaac acttagcaat aaatctaaca 69001 aaagatgtgt aattcctaca tacaaaaaaa tttcaaaaca tcgagaaaaa ttaaacatct 69061 aaacaaactg gaaaatatat catatttatg gatgggaaga atcaatacta cagacactag 69121 tcaagtgtcc ccaaattcat gtataaatgc aatgcaattc caatcaaaac cccatgtgtt 69181 tttctatgta tgtataattt aataagctat ttctaaaatg tatatagaaa tgcaaagatc 69241 caagaagagt caaatcaatt ctgcagaaca acactggagg acagaagctt caggtatcaa 69301 cacttactac aaagttatag tgataatatg gtactggctg aaacataaac aagccaatgg 69361 aacagaatag tgtgtctaga aagagacccc agatatactc ccacctttat gacaaagaga 69421 cactgaagtc tggtgaaaaa aaggtgactt ttttccataa acagtgctga gtctattagc 69481 tatccatagg ggaaaaaaaa gatgttgccc tcttcctcat attatatatt ttaaaaatag 69541 taaagtttat tagaaataaa gcaggaataa cttactgaga taaacaaaga tttcctaacc 69601 agaacacaga acacacttaa catataggga aaatctgaca gactggagta catgaaaatt 69661 aggaaattct taatacagcc aatctgtggc ccccttatgt gggaacttct tagtgcacgc 69721 agtctgataa ttcacttaat cacatttatt taacattcaa agaactgatt ttgcttttgt 69781 gaaggagtaa taccttgatt tatgaaatta aatccataaa acttatgaga ggttcaaata 69841 aaatgattaa tagttttaat aactaccaga aacataacaa aggatcaatt aaaacttgaa 69901 tttaatatgt gaagtggcat tgctttcact cattttttta aaatgcagtt ttacttctaa 69961 tcttaaatgc tactaataac actcagttat cacaggtgat taaaaatagc tgccaggtgc 70021 cctgttaagt agacaggaac aaagtcaact taaataaaag taaaggccca gagctgctct 70081 ctatggctag caaaaaaaaa aaaaaaaagc catctgctac aacaaaaata acctaaatgt 70141 ctgttcgtct actgtttatt taaatggtag aaaatcagtt tgcttagcca agatcatagc 70201 tacaacagga tcaacctatc ttcaagtggg ggaaaacaac tacctatcaa cctgtttact 70261 caaaaagcct ccttagatca gagaagcaag gggtaaaata ttggagtact ggagtaaaat 70321 aaagagatag cattagcttt ccagagggac aaatgttaaa aggccagagg ggatgacaca 70381 ttacataacc aaatgtttta aaatttcaat ttgtatgttt catgtctatg atcaaaaaat 70441 ttatacacgc aaaaaattat ttccaatcaa gaactgactt tcttttaata gaacctgata 70501 attactataa tcttatggat tctgtctaag gcataataca gcttcaaata tagaagggaa 70561 ttgagactct tcagttatac attctttcaa ggtccataat cttcaaattt ctagattaac 70621 agaaattaca taaagggcta atacagtcca actctcattc tctgcttatg ccaagcctca 70681 ttaaaataac acacgtttat ctttcagcct gggaagggca ttatgtattc tcaactacta 70741 aacactttac ctttgcagca agcagtagtc caattttgtc agcttcggcc tccaattttc 70801 tgctgtatgg tctattaaac atatactaag aagaaatgac agaaaagctc cattaagaca 70861 atttatttca cgaaaaaagg agtaacacag agagattttt aaaaaacagt ttcatggagt 70921 atctaggata aaattcctat actgtctact aacattaaaa taactccatg atataaaata 70981 taaacacagc ctttatttcc ctgattagaa atactttaaa aaatgataag gatataagtc 71041 atgcctataa atttcttgac agtctgtagt ataaggaatt tacttctatt tttccaatta

71101 tagtctccac ctactgagta caggattcac taagaaagct tattgatgaa ggctttttaa

71161 tatggtcaag gaatattttg accttgagtt ttaaaagaaa atcaagaaaa cgtaggcata

71221 taatatccaa tgacactact agacaattta tttcagtaaa aaaattaacc atatagcaga

71281 atgctctttc tttgataaat tatcttaatt tcctttttct tttctaagta ttgattagtt

71341 gggaaaatga aattttcttc tgacttcaat aaaaaacaca catagataca gtaactttaa

71401 ttttcctaat tacttgtatt tatgtgaatg ctttccagtt aaattctaat tttcagtaag

71461 tactaaaact ttgtaggaga tgaatcaata ggcaggactt ttgagaaaag agctattaat

71521 tggggaagca atctttcaaa ggtagccaca tgtctgtgat ggcctgaaat aatataataa

71581 atctgatata cagtatgtga ccattacaaa tgacttcctt ccttttcaat cagtctgttt

71641 taRgtcaatg atgtatatca tataatgcct tcactcccca tgagcaggct gcatgtgccc

71701 ccgtcaagtc tattgataac ataaggattt aaaactgtgg ctttaaaaag agagaaactt

71761 aagttcaagt ccaaatactg ttaacttatt gttaaccctg agctaattgt ttaaccctgc

71821 taaacccagt agtatcatat gtaaaatgaa gctagtaaca gttccaagct cacagagctg

71881 cagaggggat taaatgaaca aaaataacag ctcatattta ttgagccctg atttgtgcca

71941 ggtactgtgc taagtgcttt aaattaatga ttctaaacct agtgtgattt tgtcctccag

72001 ggacatttac aaatgtttgg aaatatttat tactgtcata actgagagga gggagagcta

72061 ctgacatcta gggaatgggg gtcagaaatg ctactaaaca tcctacagtg cacaggacaa

72121 ctcccccaca acaaagaatt atccagtcca aagtgtgagt agtgctgaga ttgagaaatc

72181 ctgctttaaa tgtgtcattc ggtcctcaca acagatgaac ctcagcaatt cccacaccct

72241 aatgacttca ctatcaacat tcctctctgc tctccaatca cagtgagcaa ctttctagag

72301, agaaacatct cctcgtcacc aaaattattg aggggccttg atttaggaaa aaataattca

7236l^' aatagaatca ttcctacttt attttcattg acgaattaca gtgaagtggc agaatttatc

72421 aagtatttca agaaagaaat agataaatgt tatctttctt atgaccaact gtgctgattc

72481 cattataaaa aaaagcaatc tatagataga tcaggaaaat aaccacatta attcttttaa

72541 tttcctggcg ggtcagtgac agaaacaaaa ttcaaaatat gagatcctac aacctaagga

72601 'ataaccaatc ttttattttc tctttaagaa cctttacttc aatataaatg aagccaaatg

72661 acatgttaat actgaataat agacttagtt atccaatctc aaaaacaatt tgtctcatag

'72721 aattttgcac attagattta aacagcaccc agatggcact ctgatgggaa ctccacaaat

72781 cattaaataa acaaataaca gattgttcct aaataaccaa acctcctggg acaagaggaa

72841 atattcaaag aaagatgtaa aacaaaaaaa ttatggttaa caaagtagtt ataaagattg

72901 caagacctac tttcagtatt acagtgtttt ggacaaaatg aggcactcaa tacatttttg

72961 agatgattat tatacataag cactaaaaac aaaagttaac aaacacctag taagactttc

73021 ctttcagcat tttcaaagca atgatatttt aacagagtga aaagcaagga aggatggcaa

73081 agtagcttta gccaattctg tgcccattaa agttcagagg ttttaacagt gccgcattaa

73141 aacccaaata cagttggctc tctatatctg tggattatgc acctggtaga ttcaaccaat

73201 ttggatagaa aatatctacg aaaaaacaat ttaaaaaact acaacttaaa aatatatata

73261 gtaaaataac tatttacata gcatttacat tgaattacaa gtaatctaga gatgatttaa

73321 agtatatgag aggatgtgca tagttacatg caaacaccat gcttttattt ttatttttat

73381 ttttttttga gatgtagtct cactctgtcg cccaggctgg agtgcagtgg cgcaatctcg

73441 gctcacagca agctctgcct cctgggttca cgccattctc ctgcctcagc ctcccaagta

73501 gctgagacta caggcgcccg ccacaacgcc aggctaattt ttttgtattt ttagtagaga

73561 cagggtttca ccacgttagc caggatggtc tcaatctcct gacttcgtga tccacccacc

73621 ttggcctccc aaagtgctga gattacaggc atgagccacg gcgcccggcc aataccatgc

73681 cattttttat caaggacttg agcatactca gattttggta tccacaagaa gtcctgtata

73741 ccaagggaca gctgaatttg ggagtcattc agttactacg aaaggaaggg tcagtggctg

73801 ggttttctct ctgtaaaacc aataaatata ttttcaaaaa ttttattagc caaaagttgc

73861 caagcccttc taactctcca tacccatcat ttgagagatg tagtattcct taatttaaat

73921 attcatatat aagaatatcc cctaaaaacg agaaaacata agacactaaa aattcgtacc

73981 catatttcat agtaaaatgt aaaaacatct ctggatttgc Ygctttacag tagtattaaa

74041 atatcttcac cagaggctat gatcaattca agttattgtc tcagacttac ctcctgcaat

74101 ttagactgta tccactggca caaaagtgcc aagctatctc gaggacaaat ggcccaaatc

74161 attgtgagga aaatcatacc taggaaatcc aacaaatgaa ccatgccagc cttttctgcc

74221 taRgaataat caaaataata aaaactacat tttatacatt gagacagtat atgcttacat

74281 tttctagttc atcatgtgtt acaattacct gaccttctcc acctaagact gagagttctc

74341 tttttcttct tttgcttatt ctttccgggt ctgtttttcc cttccttggt ttatctactt

74401 atatacctat tcattcattt aactagtatc taciaagcca cttactatta gtcagaggat

74461 ataaacctac aatttcttat attaacaggc ataataatct tgtgaaatag ctacaattat

74521 ccctacattt atagataatg aaactgagat agagagaggt taagagttgc ccagatttgc

74581 acagctatta ctaaaaggac cagaaatcaa acccggtcag ttttagtttt taatatagtt

74641 gcatcatttt aaaaaatcaa gtaaatgttt tattttacta atatttttgg ataaagacta

74701 aacactacct aacatatgaa gcacttaaaa caagaaaaaa ttcagaaaaa gactggaagt

74761 ttattttaaa taaaagtatt ctgatcttca agacctaata tatgaaatat tattcattta

74821 tacaagtttg taaatttgta agtctagtat ttatcatgaa agaatcaggt tctatgaatt

74881 tttgtattta cttatatcag ttaccaaaaa agatttttca taaaatagtt gttttgagta

74941 gtaatatcta agtttaatga actagattgt tcatggtttg ccattaaagg tgattagtaa 75001 atgttaatgt tgtaatgctg aaactgataa aatagcagtc attacttgaa tgtatgaaaa 75061 atgactgaaa actaaaaact gacttagaat attgtccctt aacaaatatt gtaccctYac 75121 aaaacatact ttacctcctt atatttgcct cattactttg cctcaaaaca caaatgtgtg 75181 ttttgaaaaa caattatgga tttatctttt tttttttgag acagagtctt gccctgttgc 75241 ccaagctgga gtgcagtggc gaggtctcga ctcactgcaa cctccgcctc caggttcaaa 75301 tgtttctcct gcctcagcct cccgagtacc tgtgattaca ggtacccacc accatgctca 75361 gctatttttt gtatttttag cagagatgga gtttcaccat gttggccagg ctggtcttga 75421 actcctgacc tcatgatcca cccacctcag cctcccaaag tgctgggatt acaggggtga 75481 gccactgtgc ccagcccaat tatgRaatta ttttaacatg aaaaagtgaa actcaaaata 75541 aggaagttgt tatagaagag aaagcccttg ttattaaaga atataattgc tattatacag 75601 tcttagaaaa ctggaaatac acacacaaaa acctgtattt gtagaataaa gaaaacataa 75661 acgcctagat aaaatcaaaa ctgagactcc caaaagagaa aatattgtgc tgacaatgtt 75721 taagatctct gcaaaaacat attaataact atgttctatt tttaaggctg ctgtttgctt 75781 tttacacctc atctactact gttcttgcac tgatagagat gacaatacac tgaatataag 75841 gcactgaact agatgcctaa aaaacaaatg tactgaatag taacaccttt caaatgctaa 75901 aatggccaaa actgattttg cagttgtgaa gccattactt gaaagatatt agagtgcata 75961 taataacact gcttagacgt attcttgtgt atatttgttt aagaaaaaaa gatttttttt 76021 cttacttttt tgtttgagac agtgtctcac tctgtcaccc aggctagagt gcagtggtgc 76081 gatcatggct cactgtagcc ttgatctccc aggctcaagc aatcctcctg cctcaggctc 76141 cagaacagct ggaactacag gtgtgagcca ccatgctcag ctaattttta aaatttttct 76201 gtacagactg agtctatgtt gccgaggcca gtctcaaact cctgggctca agcaatactc 76261 ctgcctcagc ctctcaaagt gctgggatta caggtataag ccactgcacc cagtcaagaa 76321 aaatgttttt aaaatcttcc tgtaactcaa aagaaatcaa ggagataatt actttcagtg 76381 tttcagaaaa acaatttagc ccatctcatc ttattaatag tctaaggaac aggtagaatt 76441 tgagattact cttagaagga ttagaatcat tatcatttcc atttgaagtt aatgttactt 76501 gtatttctga tttagcattt cagtcacttc actatgtacc tttgcgttta caatttaaaa 76561 aatactttct ctaatgtaga caaaagagcc atttatattt ttaaatgaat aacaatttaa 76621 aaaatgtgtg aaacagatgt gttatttttc ctggacttat atcaagatga acagacatgt 76681 attcacagga gcatacatca acttgaattc tatgatctat aagaaaagcg ctgctaaaaa 76741 ccaggtaact gtagtgaaag gaagaaacac tggactaaca tacagaagac ccacgttaaa 76801 gtcccagttc ggttactttg tcaggttagt catgttactg tttttctaaa cattagtttt 76861 ctcttatata aaatagtaat aataaataca tacctcattg ggtattaaaa ttatgaatgg 76921 gaagccacat atactaaaaa gctcagtaaa ctgtaaaatg gcaaggtatt gttattactc 76981 tgtattaatt acacatgaca catcattcta gacattttca aagatgctcc aagctatcct 77041 ctgagaatga ataaaaaaga aagatgattt acccacttaa atagtaatat cacttcccta 77101 caattaattt tctgactaga ttacaagtat attaataatt atagaaagtt taaaatttaa 77161 tttgaaataa ttaggggttg agaataatta Ygttttagca aaagagacag gtgataaaaa 77221 tagtatttaa gaaaaatatt attcagtatc aaatactaaa gaccataaaa attctcaaaa 77281 ttagccaatc acgttttttt caggtagcag attaaggcaa ttacccaaaa ctaaaagtct 77341 atcattttta aaaaacYtga aaaaaatcag ttctttaaaa gatttaactt gttaacttca 77401 aagcagtttt tccaaacctg aacattcatt ttaggtactt acagcatgcc caagtactgc 77461 atgtgctatt tcatggccca gaaggaaaga aagttgatga atatcggttM cactatttaa 77521 aaatccagtg aaaacaaaca tttgtccatt ctgcaccaca aagaaaataa tgtaagcaat 77581 tagaacatca taaaaaataa ggacaataaa tttaacaatt acaatgcgtt tgagaacatt 77641 tacttactgg aagcacgaag gcattaataa ttggggaatc aaccacatga ataacccaat 77701 tgatctgaga gatccctgga acatctttat tgcattcaat tagatgacaa agcacttctt 77761 taacagccag gtatcgggca tctttctcag ttagcatatc atttttaaat tcttccatcc 77821 actgaaagat taaaaattac ttcttatttt aaaagagcac tacaaaatgc ttactctgct 77881 tcatggaaag ttatatggct acttattatt gaacatttta agttttaatt atataaaaat 77941 ctgcatatat taagcactga aatttctcaa atctgaatta ttcatgcaaa gacaatgtgg 78001 tttcttacaa aggaataaat tctaatacta agttttttta tgaatagatt gacatcaaaa 78061 tttcattctt ttcgattaaa ctacaaacga atacttaagt attatttcta ctttcctaaa 78121 cattttagaa aacactgcct aggccagggc aagatggctc acgcctgtaa tcccagaact 78181 aggggaggcc aaggcaggag gatcacctca gctcagaagt tcaagaccag cctgggcaac 78241 atggtgaaac cccgtctcta ccgaaaacac aaaaaattag ccaggcgtgg tggcatgcac 78301 ctgtgttccc agctacatgg gaggctgaag tgggaggatc gcttgagtct aggaggtgga 78361 ggttgcagtg agctgagatc tcgccactgc actccaacac caacctgggt gacagaggga 78421 gatcccatct caaaaagaaa agaaaaggag agcctggaga acttaagatt tcatctaagt 78481 aaaatacaaa agaaaattaa attcacaatg cattgaacag aaaaacaccc tatacctaat 78541 aagaaagtta aactaccaaa atagacattt cattaatttt aaggtgtttt actcacagat 78601 tgaaaggaaa ttactgaatt ctcagaacta atgagcatta tcactgtctc taaaagatgc 78661 tgattaagac tagccaccac agaagatact ttttctgaag ttatattcat gagagctctt 78721 tcaagtgtac tgagaaaatt aaaaatgttc tgaaatatta ctttaacttt cataaagtgt 78781 atgctttttt tcacttaaga atcaacaagc ggctgggcat ggtggctcat gcctgtaatc 78841 ccagcacttt aggaggtggg cagatcacga ggtcaggaga tcaagaccat cctggccaac 78901 acggatgaaa ccccatctct actaaaaata caaaaattgg ccaggcgtgg tggcgcacgc 78961 ctgtagtccc agctactcgg gaggctgagg caggagaata atttgaacct gtaaggtgga 79021 ggttgcagtg agccaagatg gcaccactgc agtacagcct gggtgacaga gcaagtctct 79081 gtctcaaaaa aaaaaaaaaa aaaaagattc agccatgcca aagctgtcaa gtgaggctac 79141 tggacatgaa ttcgaaaaat attaattgag ccacagggca cataacatgt gtatgtgcta 79201 tgaactggag agaaaatgac ctctgtccct aagaaactca ctagggtaca aaatgtttaa 79261 ctacctgagt tactatactt tccaaagagg taagacttct aaattataac ttaaatttgg 79321 attcaaaaaa tataataaat tgctaaaact gatgtttggg aaaaaaatct tatattactt 79381 gattttcaag gtataagaat tctgactata aatctattta ttcaataaat atatactaag 79441 ctctactctt acatactgtg ttagtattta aaaccataaa caaaacaggt aagatccctg 79501 cccccatgaa gcttagtcta acaagaaaga caatcaaaaa aataattatg caaataatta 79561 tgttactctc atgagtgctt tgaaggaaaa gtacagtatg cagagaaaaa aagcctagga 79621 gacctaaccc cagtaaagcc aagcaatggg cgcaactaca aatgagctgg ttcataattc 79681 agtcggtatg aaggatacct cctagggcct gatccagtca ccctgcctaa cccagtctgg 79741 ataatcaagg aaggttttcc tgagaaaagt gacatttaag gtgaaatgtg ctgagcagga 79801 gttagctggg tgaatgctag gaaaagcaat gtaggcagta ggaatactaa gtgtgaaagg 79861 tctgaggcct tcgggaaaaa aaaatgctaa tttcatatca aagactaaaa ttaaaaaaca 79921 acatatcttt cacatttaag atactttcct actttgagtg ttatattaag cagtctaatt 79981 aaaaacaact cttactactt actgcttcat attccagttc cgataaaagt ctgaactgtt 80041 ctttccccaa taatagtagc ttgctccttc ctgtgattgg acttacttcc aggtgagtaa 80101 aataaaacac cacaaagagc aatccaaaac tactcaaacc aaggaatagc ttccatttat 80161 tcttccttat attttcttta actacttcct tcttgttagg aggaagtgcc tgccaccatt 80221 tccttatgcc cctaaagcaa aaagaaaaat tcaaagttct gaaaatcatt ccagcacata 80281 tcactaaagc tcaaatgcat acactagaat tttacgtcct caaatacctg aatttgtatg 80341 atgtatttcg ctgaatacat cgcttttcca attaataaaa ttcttagcta aatgatgaaa 80401 aaataatcaa tgatgtaaag ttacagttaa aaaattctaa tactcatcga aattttcttc 80461 ttcagctatt ttaaggataa acactaaatg agatgctagt ttactataac taccactggt 80521 taatatttat tactatctag tacatgcaaa attctctctc tctctctctc tctctgtata 80581 tatatatata ccatctcatt taatcttcat aataaccctg ttacagaaga taaaattgtt 80641 aggtaacttg tccatggcca ctgaggtaat aaaaggaaaa ccaagcaatg aaggcaatga 80701 cattccagag tctgaccact tagccactta atagggataa atgcctaaat aattatgtaa 80761 gaggttacag tacaataaat ctatacctgg aaccactact tttcccactg ctcctcagac 80821 ctccaacaca atttgccagt gattccacaa ggtacaaggg aaactgcctc agcattcatt 80881 ttggaaataa atagtgctca gtagcagaaa ctccactatc ctctttacaa cgtgaaaaag 80941 gagagataac aagatcctag gtattcataa gaaagtggga gattttatag ataacatctg 81001 agaaggtcca atttctacca ggcaacaata ctctctgcca cttagcagtg ttcagaaaca 81061 ttttgacaac aagcaatgtt ttcaatactg ggacaaaaat tttccttatg agttgatctg 81121 taaaatcaca acaaaaattt accatatata catcattctc ttgacaaaaa tttattttac 81181 aaattcttaa agttctcttt gtgaagtgac acaccccaat gcctttacac aaagtgtgtc 81241 catttaaagg gacataaatc aaactatcga gtatacttat ttcctattta aaactttaca 81301 tgacattatc ctttatttaa aatgtatgaa agacatattc taaatgaaaa attttaggtg 81361 atcaacaata gtaacaaaaa caagaaagtt acaaataaat aatttaaaag gatgaggaca 81421 tagcagaaat cagaaagagc atccgaagaa cctgggatga gcgtattact tcaaccaata 81481 gtcaatacag ctgtatcgct tttgggtgcc aacaccaaat catgaaaaac acaataagtt 81541 acaaatagaa gttcttggtt tttgatcaaa agcaaactgg tttggttcat gtggtagtaa 81601 gaaggctaga agggacttca cagtcatcaa acacaagaaa gctttatgaa gaaacagtga 81661 ttagctttct tccatcttca taaaacaaac aagagaaaaa gggttaaagc actacaagct 81721 gtgaaaatat tattataaag gatcaccaag gaaaaaaaca aagatttgtt gggaacagaa 81781 tagaaagaaa agaagcatta atgacttaag agttaactag gagtgagccc acccttatat 81841 aagcaaagtt cctcaatttt atgatttgct gccttaaatt ccacaaatta aaaagaaatg 81901 tttgtaagta ctcttcttat acataagtga taaccagcac ttctgatcca tatatcctaa 81961 gattttgtag tcataaatat aagatttttt taatgcctat acaaaatgta agaataactt 82021 tttaaagaga tatttctata ccataaatta gtatgcagga aattgtttca agattattaa 82081 atcatacaga acaaaattgg gcaggaccta ctgtttagaa acttcacttt gagctaaatg 82141 gggggagaca ggggatctgg caaggtttct ttaaaagtac agttttataa ataaaaaaat 82201 taatttctaa aagttaatac gttagcacaa aatattaatg caaaaagtta atataaaagt 82261 ttttattcta aaaaagcatt ttacctgcct acaatgattg caaataactt ctgtactggt 82321 ttaagaatca tcaacaagag aggaaccgga gcagcttgaa accgtggaga agtatggaaa 82381 ttcctaatag ctcttatgga agcagggctt agaggatgca atactgacag actagggact 82441 gctgtaactt cttttattag cagctgtctt gaaaaagcat cattccatac agtacatttg 82501 ctggtaatcc tccaaatttc cttacttttg gtacttgaga ggcctcctgt tcttttgttg 82561 ttaaaagtac tataaaaatg aaagtttcca ggcagaaaac tccacctgtc acactgattt 82621 actcccagtc cctgatactt atttactata tggttaactt gtacttgRtg acagccccgt 82681 gaggtggatg ctaatgtgtt acattttctc cagttagaca gtgaattaaa tcggaagaaa 82741 acatggtttc tagcagcaga ctgcaatcca cagatgaagc tcattttttc acttgaYtac 82801 ctgaaacaaa aaaaaaacta taaatatctg tggaaaatat ttacttacca aactgggact 82861 ataacactta ttaaataggc gtgtcagttg ttcttctaac acatctcagg ctaaattacc 82921 ttgggtttca actcatcacc cctagagcaa cgcctttcag caagataaac cagagtatat 82981 ataccacgat atttactatg caacRtttac tttagaagct tgaatttttt Ncatttcatt 83041 tttaattttt agttagggaa gagccatttg tattttaatg gcaaatgatt tgagcaataa 83101 agtggattag ataaaaacaa cagtaaaact ttatcagttt gcaataactg gaaggaagca 83161 tgtgatacag aatagtaaaa tctaacttat aaaatgcact ggacattacg caatgaagaa 83221 cagtgatccc taacagatgg gaaacagagc cctacaactg tcctagctta ttgcctggag 83281 agtgcttcca ggccacaatg cagacagggt aaacctaggt ggagcccagt ggttccccta 83341 aatcgaagag ataaagctgg gaggtcaagt aaaccaaggt tgctagagct cacaggacag 83401 aggacaagag aagacaagag ctgcacagag aaataactct agagttctgc agagaatccc 83461 cctcccatat tcagctgagt cctgtctggg catatgtgta agaaaattcc ctggagctgg 83521 gaaagggcca cctgaaaaga ttgcagggaa taatatacag ggctcacaca gggcatggta 83581 tactgcctat cccctcccca ccattcaaag tggaaaacct tatcattcgt gggtagagta 83641 ctcagaaggg ttttgcctca acattagaga aagattagtc tgagaccgaa agctgctctg 83701 gccccaccta acaaatatta aaagcaaccc ccaaaaagat taaatgcttc caagcaacaa 83761 ctgcatccca ggaaaaaaaa aaaatctaaa caggtattag gacacaaaac tatttaacac 83821 ttaacaaggt gcaatttata attaaaaatc accaagcatg caagcagcaa gatatgtgat 83881 ccacaattag aagaaatatc aatcagtgga aactaactcc taaataaaca aataacagca 83941 ttagtagata aggatattag ttattgtaac tatactgcac atgtttaaga agctaaagga 84001 aaatatgagc atgttatgta gagatatgta atatatttct ttaaaagacc taaactttta 84061 gacaagaaaa ctgtaagaac taagatgaaa aacatactag atgagactaa cagcagatta 84121 acattgtaga aataaagatt tgtgactttg aagacgtatc aatagaaacc atctaaaatg 84181 aaatacagag aaaaaataca ataataaaaa aaggcacagg gcatcaatga ggtatgcaat 84241 aacttcaagt ggcctaatat tcatctaact gaagtcccca aaaagcgggg aggaggtgta 84301 gacagaaaaa aaaaacactt gaaataatgg ccaaaagttt tccaaacttg atgaaaatta 84361 taaaaccaca aattcaaaaa gtttaacaaa tcctacacaa aagaaacaca aaggaaaaaa 84421 actacaaggc acataacttc ttaaaatcaa tgaaagataa aatcttaaac ttgacatctt 84481 aggtgaactg tataaattca ttgaaaaaca caaaaaaagc tgggcatggt ggctcacgcc 84541 tgtaatccca gcactttggg aggccgaggc aggtggatca tttgaggtca ggcattcgag 84601 gcgtgaaacc ccgtctctac taaaaataca aaaattaggc aggtgtggtg gcacttgcct 84661 gtaatcccag ctactcagga ggctgaggca ggagaatcgc ttgaacccgg gaggcggagg 84721 ttgcagtgag ccgagatgac gccactgcat tccagcctgg gcaacagagt gagactctgt 84781 ctcaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaacaggaaa aacacaagaa 84841 agtacatact ctgattacat ctctataata taaactgcaa aaaatgcaaa ctaatccata 84901 gtgacagaga gatgagtgac tgcttgagga gttgtaggaa aaaagcagca ggggaaggga 84961 ttacaaagag tggtgcttgc ctgtaaaccc agctacttgg gaggctgagg caggagaatc 85021 acttgaacct gggaggcaag agactgcagt gagccaaaat tgtgccacta cactccggcg 85081 tgggcaacag aatgagaacc tgtcaaaaaa aaaaaaaaaa aaaaaaaaaa accaaaaaca 85141 aaaaacaaaa aaacccagat tgagggaatc taaatatgaa ttgaatttca agttgtttta 85201 ggtaattatt attttcttag gtgataatat tgtggttatc tgactatttt attcctgaga 85261 tacttgctga aggatctgtt catgataaat aaaactcact ttcaaattgt acagcaaagg 85321 tacacacaca aaggacataa agtcaataaa caaaatatca gcaatcattg tatctcagtg 85381 atagttacat atgtgttcct taaatttttc tgcatgtttc aaaatcttca tataaaagtt 85441 ggggaaaaaa atatgtaaac ttcaacctaa gctaatacga tattatctag aaagatgctc 85501 caggactacc agttttaata gtattatcta tatatcaaac catttgaaaa ttactcaaat 85561 ttatttttta tgtaattcat acatcctgcc cttgcactgt taatgtataa tgttaataaa 85621 gggcatgcta agtaaaacat taactttgag ttaacccttt ttgaaataca acc^'aatttta 85681 aattagtaaa gtccaggctg atatataata gtttgacatt attaacaaga tactttgttt 85741 ttactttttt gaaccaagct gaaaaattgt taaataattt aagcctagaa gtcatttcac 85801 aattcatact ggagtagcta gtaaggtttt cattggctag gggccatgag agttatgcag 85861 cacagaatat agtcctgctc tcatggaggt tataatctag ttggggagac aaaactgaac 85921 ctaagtaaga ctattagggg ataataaaat tcagttatta aatactacat actgtatgca 85981 ttcttaaaaa gacatccatg agtagctgaa gagttcagga aggcagcaat tatttttcat 86041 gccatttagg cagatgcaga aagacaaaaa aaaatggaaa gaactgtttt aaatgggaaa 86101 gtgtWttaag gtttaaatgt aaagtcttct tctagaagtc aaactgcaaa aacaacccaa 86161 gcccactttc tttccttgac ctcaaatctg atgatttact gtagtagata agcttcagac 86221 acttgcccaa gcacaagtcc ttttccaaat gtgcatctta cagcctcatt ttaggggaca 86281 ggcttagacg gccacattca tccctagcaa cccctaccat tagctacaga gctaggagta 86341 ggtatttgat actgaaaaga ttttacataa aacagtattc cgcacaggaa tataagggca 86401 tgtgtaagtt gggtctacag cgggtgctat ggctaaacaa agcaatatga aagcaagaac 86461 tacaaacaaa aagctttttt aaaaaaaaaa aagtggatcc acagaaaaga caatggacta 86521 ttaagtgtag acagaagata agtgagagac cacaaagcca gagtgaatat gagagaataa 86581 gacctccctg attcccatga aaccattgta cttcctacac ttaattgagc ttcatgagct 86641 tttactttat ccccaaaata atgcgctttc ttcaatgagt ttctgtattc tgcaaataaa 86701 tgatctctaa gacgtttaca tggtataaaa cagttataca tttgtttttg taaattgaca 86761 gcattttaat attatacatg ttgtttactg gaactagctg agggttcctc ctacactttg 86821 caaagccaaa tttaccaatt ttcaacattt aatcagttcc agaaatactg gattatctct 86881 acagcaactt tagcatccaa aatatctcag cccacattaa atcagtcatg tcaattctac 86941 ctccttctta tctcattcta gcctttcctg ggctctgtgg tcttatggtg ttgatcacta 87001 cccacctaat ctccctgcct tatttcacca ctaacccctc ccactacagt ttgaccccaa 87061 actagagcta aagcattatt tctaaaatgc aaaccctggc aacagaatcc taccccgaca 87121 attaacatac agtcctaccc tggtaaatac caggtaatca tttaaaaaat gacatgatga 87181 tctgtaaatc tttaaaagat ttaaaagata gcaatctctg gcaaagggat atacaaattt 87241 aaaaataata ataaatgcta cctaaaaact tctgtataac agaggtggca aactcaaacg 87301 tctaaagaag caccatacaa cagacctttc tacaatgata aaaatgttca tgtctgcact 87361 gtccaataag gtagccccta catgtggcta ctgagcattt gaaatgtgac tggtgcatct 87421 gaggaatgaa atttttaact cagttaaatg gccatatgtg gctagtgtct actgtatcgc 87481 acagtacagg tttgtagggt ccaggcaagt gaatatcagc aaagtgatac tgatgtgaat 87541 gcagattcat gaccatctaa aggaggtgca aacagttatg atggaatttg aacttgctgt 87601 ggccaaatga ttcaaaactt ttaagtaaag ccagaatttc agattttagg tgaaatttat 87661 caatttttaa atgttggcaa tgaacttaaa aaattttaac gaccttaacc aaacattcag 87721 attttgtatt tttgacctct gaactgtatt attattcatt cattctgaaa atgtttaatg 87781 agtgcccact aaatgctagg caccataatg gatgctagag atactgcaga gaacaaaaca 87841 gattttaaaa aaccctcccc aatttgcaaa aatagtaatg agaaaatatg ctagtatata 87901 caaaaataaa tctgaaaaaa gatacaccaa actattcaca attattttga atggcaggat 87961 ggtggttaag agggattatt agtattttca ccttatatat ttctgtgcag ttcaaatttc 88021 tacgggatgt attattactt ttttaaacct ccactcaggc aactatttct gtaattccca 88081 ttgtttttct tttcttttcg agacagggtc tcactttgtc gttgtccagg ctggagtgca 88141 gtggtgccac ctcggctcac tgcaacctcg cctcttgggt tcaagcaatt ctcgtgcctc 88201 agtctcctca gtagctggga ttacaagcat gcattaccac atctggctaa tttttgtatt 88261 tttagtagag acggggtttc ggcaaattgc ccaggctagt ctcgaactcc tggcctcaag 88321 tgatctgctc acctcggtct cccaaagtgt tgggattata ggcctgagcc accgcacctg 88381 gccagcccag ctaatttttt aatttttttc tgtagacacg gtgtgtcact atgttgccca 88441 ggctggtttt taactcctgg gctcaactga tcatactgca ctgcgaagtg ttgggattac 88501 agtcatgagc caccacgcct ggactttcgt tggttttcca tggcttccac aaactccttc 88561 atatggcgaa ccaggccctc ctactacttc tccaggcacc ttccccaacc ctccttcacc 88621 cattcctaaa ttccaaactc cctgatttac ttacacccca cagaaaaaga aagctctcat 88681 ctctatgtct atgcacatct attcacactg cttagctctg cacatgacaa gcaaactcct 88741 tctcatttct catgacttgt gtaaaaattt taaaagaatc ctattgacac agaaggtata 88801 agcaaaagcc ccaacactac gcatatataa ttaaaaccat tatcatttct atcactgaca 88861 accaagtgtc gttttgaata gaaacagtgc ctgatatttt gtaatacccg gtttatcctg 88921 aagaaagggt aaagaatgag ggaagaaatc tattcatgca ttttcaagga gccaatcact 88981 agactacaga gcacaYaaga aaaaaaaaaa tcagggctga catattctct tcaaagagct 89041 gtggcaggtc aacaaacata gctggcagac ttctaggata acaaaattaa tgatgtgaga 89101 aaattaaaca atttggattg ttagcctcta cgaacatttc agatccttaa ttctttaagt 89161 accatctccg aatgagcaag tgcagcactc actggcactc acagctgaag cctggaagac 89221 agttttaaca actcttgctg aaaatgacta tttcttctct agtttctatg gaaacagctg 89281 tcagattggc aaaaatagga catgtacttt aaaataatca ttcaagcaaa gtacacacat 89341 gatggaaggc tttaaaaaag aattggacgg cagcagactt ggttcttaag Mttccaaatg 89401 tcagactaca ccccttcacc ccggctgaga atgacggaga tgaacctaaa tccttttagc 89461 gagggttgca cgaccttgat caacgcctga atgccaaata agggattttc atctccctgg 89521 actacaattt cttgttgagg attgcacggc acaataaaac tgttgctcca cacacaggcg 89581 acatttaaac agtatacagt gagttctgta gacgagttta cgaggaaatt gttaaaactc 89641 cccggaactg cttagacggg gaatgttctg gtttgccctg ccgagtttag gctggaaaac 89701 gtgttcagtt tctcctgaag agggaagggg tgaaagagac gRatgcccga cgcgccggga 89761 ggcggtcccc tctggcagag gtgccgggtg aggagcccga agYcMcgcgg gtgagaaacc 89821 ctgctctgaa agcggagccg cggataaggg cgggctgagg gggagggcag gcggcccacg 89881 aaagtactgc cacggggcag acacacgggg tcaccggcgt gccccgggca aggctagggg 89941 agaaccgggc tcccccagga cagatcccct ccgtctcccg ccccggcgcc ccccgcccct 90001 cccctccacg cagccttatc gcccacccac gcctcctccc gtacccccat ccccaaggat 90061 ccccactcct tgcccgggcg cccccgcagg cgctctgcgc tccgccccct ccccactgcc 90121 gcactctgcc tcctcccctg ggcacgatcc tactcggaaa agctggggaa aagcgtcacc 90181 gtgaggactg actcaagcag aagcgaaagc ggtgacaccg cMgacccgac ctatgcgcag 90241 gcgcgcacYc gcacttcctg cccgccatac cggccggggc gcccttcgct ccgcccacac 90301 ccggcagtca atacagccgc ccagagtcgt tctcccagct gccccgggcc ccgcggagac 90361 tgtggcgctc tagcgcctcc gtgtggctta aggcgggaca tggccctggg ctgggctgct 90421 tgcctaggaa caactttctc ccgtctttgg tgagttgggt cctctaaaga atgatccacg 90481 caaggctgtg tccgttgtag tctctacggc agtaccggcc aaaagggaag agactcgaag 90541 actgccaaaa gacgaaggct tcctggttct gaatctgcat tcatagaaat agtctttgga 90601 gtatgggaac agtgctttca tatgattttt ggagggacgc attttaagaa agatgaagta 90661 taatcttaag tgtctggagg ttaaagtagc tggctccaaa attatgtgta tagtatgttt 90721 cattcatttc accaaaacat atttcttgag catcaactac attttaagtg ccaaggatgt 90781 agcagtgaac aagacagacc tgaatttcgt gaactttata tcacagtgag gaaagacagg 90841 cgattaaaaa aaagtgtaca aataaacaca aataaataaa agtgtacaaa taagccagta 90901 caaataaaca ctggattgtg atggatgagt agtgaggtct catattagtt tattatgttt 90961 acactctgtg cacaatgaaa acatctcaaa ggacataaac actatgtcaa aggacataaa 91021 cactatgaac aattttaggt atctcttttg gaaaatgtgt aagttactgt ttcgtttatc 91081 ttatgtgtat tttatgattt gccttttact ttgaaaggga tatcctggaa aacccctgac 91141 aactggaccc ctaaaaactg aagtaggagg tccttcagtc ttcgtagggt ttatctccca 91201 aactctggag tgcacatgtc ttaccaaagt ttccagcatg ctagccacct cttgctcatc 91261 ttgcctggtt agcataatgt cattggtgaa atagatgggt gtgatgttct ctggaatttc 91321 cagttgatcc agctcctttt ggactgcgca gagccattat gtcattatcc tgggtccacc 91381 tgatttccaa aggggccaga ctggcaagtt aagtagagat atggcaggga tgaccaacca 91441 ctcttgtata tttYaggtct ttaattatga cattaatctc caccatcatc tcactatccc 91501 ctcagatgaa atatcggttt tgatttatta tcttcacttg gaaagaagga cagcttcaga 91561 ggcttcccat tggctttccc caccatgata actcaagacc aaggaccctg agcttcttac 91621 caatgtggag attgctccag ctgcccaata tgtactccca attatgcact caggaactaa 91681 gaaaatgact actggatggg tcagtgtatt cctggaccca ctgtaagctg gacattatcc 91741 aggactctgc ttattacctg atccccataa gcccccacac ttagagagga gccatgtgtg 91801 ttacatactt tgggtaacac ctgtgaaatg tctgggtatt cctctttcct caacataaaa 91861 tcagtcaaga aaatggccgt gggacacaga ccaaagagta atcattaatt acagtaaata 91921 tttgtttcag tattgcagga ttcttcttta tagggaccca acaacctctt aagtcaacag 91981 attctgtggt ctcagtgtga agataggctc aggtctgaga cttgagcaat gagcagtgcc 92041 ttttattaag caactactcc ctgcatagga taaatagctt cttgtcttcc tccagttgta 92101 gatgttaggc aacactcttg ttggctgccc gtctgttttt cccctaggga gaccttatgc 92161 tattaaagcc ctccacaacc tcctgtggat caagccccct tggctgctcc tctgcccttg 92221 gcagatgtta cagtaattac atcttctggt gtcctcatgg ttaaagccac cacctggctt 92281 ctactacttc aggatcctgt tatcccaatg gatattatca agcccagccc tgtgattgcc 92341 tctcctaccg tcagcccttc cctccagagg agagccttct ctgaacttct tagtgatgct 92401 agtgcccctc acgccagtgc attccccatg gccatagaat atgatgcatc ctctgggcct 92461 cccatggaac attcccctct gtctgccttc gggctctaca cacaaaaaaa attctttcag 92521 gcaagtccac ttccctcagc tcctctgtcc ttctaccatt tgcaagggca attcgggcat 92581 tcctgcttta ctctgcatgc actatggctt tctctcagct tctaatagtc acctagcagt 92641 gagtttaccc atcttctaca gtcccaagtc ccaagaaagt gcccccaaga caatgaattt 92701 ttatttagcc aggcttgttc tggaatagga attaaaagaa attaaagaat gtgtaaacag 92761 aaactcagtt ctatgtaaga aaacccacct ccccccgaga aagagaaaga gctggagtcc 92821 tttaaatatt aactgcctgt ttttctgtgg ctagtgagcc ttatctctcc ctttcccagg 92881 cattgtaaag accctgtttc tttagctgtg cgctgcaagg tcactagaca gataaactca 92941 agccattaag acacgttttt ccttgaaaag taagaaatga tgtaatgcat gcctcaatta 93001 attaaataac tgtctttgtt tcttgcttct gtaacatgct tctccctgca cagatctccc 93061 ccaaccccat aaaatgctta aaaggtaact tgactctttg ttcggggctc agtcctttgg 93121 atgttaatcc gactgggccg gtgcacctaa ataataaatc ctcctcaacc tcttggtatc 93181 tctgattcct tatcaatccc gccacagttc ctgcccactt tgatcaagca ccttcagaaa 93241 tcccattcca ggggtcctct cctggctcct gctggtacac gctaggtagt tcctttagct 93301 cctacattat gcagtcttcc tccccacacc tttacaggcc caacacacag gcagctgggt 93361 gatgctggaa tttaacctga gttatcaccc tggcagatat ctaagaggag atggggcagg 93421 tcctgagtgg gcacctattt attccttacg ctagaggctt caacactgcc ttcccactta 93481 agggaagtgt tagctttgac tagggaaggg tcagccacct ctgcaagctc tgaggatctg 93541 cagtcagtat cctcagggat tctatcagga tgtcccattt catgcttcaa gattccagat 93601 tttcccaacc agggcccaga cctgccttgg ctaagcgttt aaa'catctct ggggctctac 93661 aactcttttc atgaaaatct cttttgctcc tctgctgtcc acactcctcc actgcaggtg 93721 ataagagcct gtctgttacc taccaaggag acctctgact cccactcagc cttaactgtt 93781 tacaaatgac cctcactttc tcattatccc atgcagggca tcaacacaat gtagcaataa 93841 ccagcccact gcactgttct ttcagacact gctccctcca tctttcaagt gcattaacta 93901 tctcacctaa atggcattgc cctccactgg gccagtttcc caggtcgcca tcactgaaat 93961 ccacacgggg gccactatct tgtgccagac actatccaag accccacatt ccactcaaga 94021 tggagttctt gtagccagtt gggcaattaa tgagccactc tcagagccga tcttaccatc 94081 ttcttctcag atcaccccac ttctagtcca cctgtatcaa caggccctct aaaaagcaga 94141 tgccagggtg gaatcagatg tgcaagacat atttactgcg tggaaaatcc tgggaaggat 94201 aatggagcag gagcaggaat agacaggaag ggccctcaga tcatgacact ggttaaagga 94261 gagagggaaa gaagaaagac tggattagaa gcacctcagg ttgtagcaca gttctaagaa 94321 ggttttgaaa atgaggagtc cttaggccaa aattgcctgc ttagaggagt tccatatttt 94381 gcagagatgg gcatccacta gtgttcacac catgcRtKat cattggctaa gagcagtcta 94441 tggggagcat gcgcttgtta caaatggagt tggggagcca gaaggtcagg ggcagggcct 94501 ggcagtcaac tatgctcccc agagcagatc tgagcggcac attttcccgg tcacggctgc 94561 tggaggattt agagtttgaa taagtcYtct gttctggctg tacatcttct ttgtgctgcc 94621 ctttaagcaa ttttttaatc aacgtgctat ggactgaatg tttgtatccc tctgaaattc 94681 atatgttgac ccctaaattc ccaatattac agtatttgga aatgggggcc tttaggaggt 94741 aattaggtca tgggggtgga gctctcatga atgagattca agtctgtaag gagataaagg 94801 gatcagagag ctcccactct gccacgtgag gataaaacaa gacagctgtt cgtacacgag 94861 gaagagggtc ctcacaaaat ccaaccatgc tggcatcttc atttcagact ttcagcttcc 94921 caaactgtaa gaaaaaatag tttgttgctg aagccagtca gtctaYagta ctttgttgta 94981 gcaacctgaa ctgactgaga cacatgatca gattccattc tcagaaccaa ccttccaacc 95041 aagcaatatt gatttgctac acttaaaagt ttggcttttg tcaaatttcc aaagctattt 95101 accccgtctg aattcagagg attgacatga ataatttcct ttggatatgc ccttgggaaa 95161 agggcttcat tttaagcaca gcttaatgag gtgtaagaag cttttgaagg tgttctttac 95221 agagtattca tggtaggagg Kttgcttgaa gggtcacact gaagactgtg tcccgtgaca 95281 gcatcactga agtttgactt tggatgtaac actgaaagta gatgctgtgc tacaccagca 95341 gatccccatt cactgaagtt atcattctgg cagctgcctg cctccctaga gatttccctt 95401 ggctggagac accKgcttca tccaaggata ggctctctgc ccagcgacaa cacttacccc 95461 acaaactttg ggagtacaca gtcctgactc ctatgc tca attgaggata acactgcaag 95521 gccatccacg cggcagagac ctccatggga ctggaagctc cacttctgcc tctacccagt 95581 cctgtttccc ttactccctt ataagtgttg ttccttggcc gggcacagtg gctcacgcct 95641 gtaatcccag caacttggga cgctgaggtg ggcagatcac ttgaggtcag gagtttgaga 95701 tcagcctggc caacatggtg aagcccctgt ctctactaaa aatacacaca tacacacaca 95761 cacacaaaca cacacacaca cacacacaca cacagagatt agataggcat ggcggctcgt 95821 gcctatagtc ccagctactc gggaggctga agcagaagaa ttgttgttcc ttggccgggc 95881 acagtggctc acgcctgtaa tcccagcaag ttgggacgct gaggtgggca gatcacttga 95941 ggtcaggagt ttgagatcag cctggccaac atggtgaagc ccctgtctct actaaaaata 96001 cacacataca cacacacaca cacacacaca cacacacaca cacacacaca cagagattag 96061 ataggcatgg cggctcgtgc ctatagtccc agctactcgg gaggctgaag cagaagaatt 96121 gcttgaagct gagaggcaga ggttgcagtg agccgagatc acaccactgc actccagcct 96181 gggtgacaga gcaagactcc gtcctaaata aataaataaa taagtgttgt tcctgaggtc 96241 tctcccctat aagcctgcac aaaaagattt atctcagaat ctgtttccag ggaacccagc 96301 ctaaaacaat tcagtcttct ccagtggaaa actatattaa atgccatgac acagaaagac 96361 attcattcac acctcctata gaaagtgctg gatgctgaat actgagttaa agaagagagt 96421 gactctgaag aattatgagg catggcttgt cttataacag gtttagacag aagttcaaca 96481 gacaacaatc aggcctctga tgatatagat tcagaatgag aaccaggtga aacagccaca 96541 ggatttgatg agggtcacgt acttggaagg ctgcaatgta tgggtggcac cttgactgaa 96601 gtggcctttc gtttttcttg aatatgtgcc aggcatgact gtccaaaagg gttgaaattg 96661 tgaatttgaa atcactccaa cacagagaat ttcagcatct tcattgaaac Rttctactcc 96721 aacaaaaatc agctcagtgc ttacttcaac cacagttgac ttctttttct ttcttgtgtc 96781 atccYagccc ttcttcccac ataacatgaa taaatctgcc attttaaagt taattttttg 96841 cttgaagaga atggtcacac caagttccag tgtgttattt ttacgaattR ccatctaaat 96901 tattagtgca ctagtatcct gactggtctc cctgtctcca gcctcgttcc tcttgtctat 96961 actgcagcca ccaggaccca gctcctgaaa ttgggtgtgg gataattcag tatggctcag 97021 cgagctccat gcagggccat gggggaaggt cttactgtgg acatgccctt gcYcactccc 97081 cagagatcag ttcttcaaag atgccagatg agcacttttc taagtgtcag tgcaaactat 97141 tatttcttta ttgcacaagt gaaatactaa taccatagaa aagcaaaaca aaaaagagaa 97201 aaatcaccct taacctcact atcccaaaat aaccaYtgtt aacattttga tgcgtaaccc 97261 acttgaaaag caagatttaa attaccttaa atatttaaaa cattgatgag atcaaagctt 97321 cctcgttgtt ttgatgKgta ttcctttgat ttataataat gtaaatgctt tttcatgctt 97381 ttatgctgtt tggatttctt ctttagcaaa ttgcctgttc atgcccttaa cccatttttc 97441 tgtaatatat tcatttgtat cttataaact taaaacattt ttttatacat ttaagaattg 97501 tctgtcattt atgtagcaaa cattttcccc acttgaagtt tgtctttcaa ctttgttgat 97561 tcaggtgaaa aataYactta attgctgaaa ttttgataca gtcaaaaata tccatctttt 97621 cattatggtt tctgccttcg agatcatatc tactgtctgt ctcaaaatta agattaaata 97681 tttatcatta ttctagtact tgaatgactt tgttctttct taaatctttt aaaatattta 97741 atctaccagg aatttatttc agcataaaat aggaggaaaa aaaataacct aaaatatttt 97801 cggaataatt aggccagtgg agcttttaca aaggatgcat gcatgtgccc tccccatggt 97861 taggaccacc aaagtaactg ctgtcccaac aattaattta acatgtcctg actgacttaa 97921 agcatcactg ttacgatatg ctaaattcct gtaaatatct acatatgttt ctgcagtttc 97981 cctttttttc cttggtctga ctgttctgga gttagtgcat gattctttct atttattgta 98041 actttgtaat atacatttta ttttcaaata ttgtctggct cttacacatt tgaccttcaa 98101 gatgaacttc tgaacagttt ttttccagct cccttcctaa aaaaaaagga attgggattt 98161 ttgattctgt tattgttgtt gtttttaatc ttggattcat ttgggtgaga tgtatatctt 98221 tgcaatgttg actgtcaatc taggaaatat gtgcatctcc atttatccag gtcttctttt 98281 atgtctctcc ataaagtctt acagttttct tatatgggtc aaagcagtat atttttaaaa 98341 ggaactataa actttacttc ttaggattat ggaatctcag cgcttgaaag gacttaaaaa 98401 tcacctcact ggccRggtgc ggtggctcat gcctgtaatc ccagcacttt gggaggccga 98461 ggtgggcgga tcacgaggtc aggagatcga gaccatcctg gctaacacgg tgaaaccccg 98521 tctctactaa aaatacaaaa aaaattagcc cggtgtggtg gtgggcgccc gtagtaccag 98581 caacttggga ggctaaggca ggtgaatggc gtgaacccgg taggcagagc ttgcagtgag 98641 ctgagatcgc gcgaatgcac tccagcctgg gcgacagagt gagactccat ctcaaaaaaa 98701 aaaaatcacc tcaacactcc caccccatct gctgctgagt ccccatctca accaaagata 98761 tgtggcatat ttttagtggt tttttttaac ataatggtat cacactatga atattttctg

98821 taacttccag gttatcactt gcacaacatg ccttggagaa atgtctttat caatacttgt

98881 agatcaattt aatccatttt aagcaccata agatgtcctc tggaaaagat tttgcatcat

98941 ttactttatt actgttgatg gacatttaaa ccatttctat cattttgctc tcacaaacaa

99001 ctcagctcat aaccttgagc tctaactgaa gtaagtctcc aaattcctag agcacacacc

99061 actgggggca cagttcccct cctcatatat cactaccaag tgttgtaatg cctgttcaaa

99121 gaaaggcatt Ygtttacctt tccatggagt ctcaattctg ttcaacaaac atctattgcg

99181 catgaattat ttagtaagta ctgggctttt tgtttctaat cactaagatt tattttttag

99241 ggaaatttta ggatcacagc aacattgagc agaaagagtg ttttcatcta ctccctgtcc

99301 ctacatgggc acagcctccc ccaccaccaa gagtggtaca tttgttaaaa ttaacatgcc

99361 attatcaccc taagtccRta gtttatatta caggcatttt taacacacta attttgatac

99421 aataaacaaa tctatatatt caataatact atggaggcta cactatatgc cagatactct

99481 acagaaMctg gtgctccagg gaaaatagga aatcccctac tcctcctctc aacctaaaca

99541 attcccaaaa taaaacatgg gtcatcacat catggtatct atttatttat aagcacaggt

99601 gactcttcat ctatcagatc actagaccag gtagcagatt tccaaataat ttggataacc

99661 tctggaattt gaggtatcca tgcttaaatt tccatgttct tatacatgYt acWctttctg

99721 tgtgtctccc aaggagacct ccctattaga cagcatccca cacagaaaga gtagcatgta

99781 caagaYgagg atacaaatgt gacaagcaca aagattccaa tacaagtaac ttatttggga

99841 ggtgatccta ggaaRcaccc attggtgagt agagaagtga gacagggaag gaaagaaagc

99901 taataaagaa tacattaaca aactagttac aaaaggggcc aatggggtgt cgtccctctg

99961 aggactgcta ggagaatgtg taaaacaggc cacagagttt taccaagtga ggatgggaaa

100021 gctgggctat ttattcacca ttcctgccag tagcattggt tgagggctgt cctagtaagg

100081 attaattcta ^■tgacacttcc

[0312] Following is a LOCI 15209 genomic nucleotide sequence that includes the LOCI 15209 SNP "MRP1-AA" (SEQ ID NO: ).

CATTCTTTGTTTTACATGGAGCATATTAGGGATTACTGAAACAATCTGAATACATTGATGTATATATATAGTATTTTTTTA

TTTTATTATTTCTTTATAGGCTCTCAAAATTAGAGAGATGTGTAATTGTCCACCACTGTCTAATCCAGACCCTCGATTACT

ATTCAAACTCAGCACGAAGCATTTTCTTGAAGAATCAGAGAAAGAAGACCTAAATATCACGAAGAAACAGAAAATGGATAC

TCTTCCTATTCAAAAACAGGAGCAAATACCATTAACATACATAGTTGAGAAAAGAACGGGCAGTTGAATTAAAATTTATGA

GACACAAGATATATGAAGAATGTTGCAGTCCTTATCATTTTATGTTACTTTTTAAAAAATGATGTTTGAAGTG[A/-

]AAAAAAAAAGGATATTCAGGGTCAAATCATGTACATTACAGATAT

[0313] Following is a LOCI 15209 genomic nucleotide sequence that includes the LOCI 15209 SNP "MRP1-AB" (SEQ ID NO: ).

AATGCCTTCGTGCTTCCAGTAAGTAAATGTTCTCAAACGCATTGTAATTGTTAAATTTATTGTCCTTATTTTTTATGATGT TCTAATTGCTTACATTATTTTCTTTGTGGTGCAGAATGGACAAATGTTTGTTTTCACTGGATTTTTAAATAGTGTAACCGA TATTCATCAACTTTCTTTCCTTCTGGGCCATGAA [A/C] TAGCACATGCAGTACTTGGGCATGCTGTAAGTACCTAAAATG AATGTTCAGGTTTGGAA r

[0314] Following is a LOCI 15209 genomic nucleotide sequence that includes the LOCI 15209 SNP "MRPl-AC" (SEQ ID NO: ).

CTAGGGGTGATGAGTTGAAACCCAAGGTAATTTAGCCTGAGATGTGTTAGAAGAACAACTGACACGCCTATTTAATAAGTG TTATAGTCCCAGTTTGGTAAGTAAATATTTTCCACAGATATTTATAGTTTTTTTTTTGTTTCAGGTAGTCAAGTGAAAAAA TGAGCTTCATCTGTGGATTGCAGTCTGCTGCTAGAAACCATGTTTTCTTCCGATTTAATTCACTGTCTAACTGGAGAAAAT GTAACACATTAGCATCCACCTCACGGGGCTGTCA[T/C]CAAGTACAAGTTAACCATATAGTAAATAAGTATCAGGGACTG GGAGTAAATCAGTGTGACAGGTGGAGTTTTCTGCCTGGAAACTTTCATTTTTATAGTACTTTTAACAACAAAAGAACAGGA GGCCTCTCAAGTACCAAAAGTAAGGAAATTTGGAGGATTACCAGCAAATGTACTGTATGGAATGATGCTTTTTCAAGACAG CTGCTAATAAAAGAAGTTACAGCAGTCCCTAGTCTGTCAGTATTGCATCCTCTAAGCCCTGCTTCCATAAGAGCTATTAGG AATTTCCATACTTCTCCACGGTTTCAAGCTGCTCCGGTTCCTCTCTTGTTGATGATTCTTAAACCAGTACAGAAGTTATTT GCAATCATTGTAGGCAGGTAAAATGCTTTTTTAGAATAAAAACTTTTATATTAACTTTTTGCATTAATATTTTGTGCTAAC GTATTAACTTTTAGAAATTAATTTTTTTATTTATAAAACTGTACTTTTAAAGAAACCTTGCCAGATCCCCTGTCTCCCCCC ATTTAGCTCAAAGTGAAGTTTCTAAACAGTAGGTCCTGCCCAATTTTGTT Following is a LOCI 15209 genomic nucleotide sequence that includes the LOCI 15209 SNP "MRP1-AD" (SEQ ID NO: ).

TGTTCTTCATTGCGTAATGTCCAGTGCATTTTATAAGTTAGATTTTACTATTCTGTATCACATGCTTCCTTCCAGTTATTG CAAACTGATAAAGTTTTACTGTTGTTTTTATCTAATCCACTTTATTGCTCAAATCATTTGCCATTAAAATACAAATGGCTC TTCCCTAACTAAAAATTAAAAATGAAATGAAAAAAATTCAAGCTTCTAAAGTAAA [C/T] GTTGCATAGTAAATATCGTGG TATATATACTCTGGTTTATCTTGCTGAAAGGCGTTGCTCTAGGGGTGATGAGTTGAAACCCAAGGTAATTTAGCCTGAGAT GTGTTAGAAGAACAACTGACACGCCTATTTAATAAGTGTTATAGTCCCAGTTTGGTAAGTAAATATTTTCCACAGATATTT ATAGTTTTTTTTTTGTTTCAGGTAGTCAAGTGAAAAAATGAGCTTCATCTGTGGATTGCAGTCTGCTGCTAGAAACCATGT TTTCTTCCGATTTAATTCACTGTCTAACTGGAGAAAATGTAACACATTAGCATCCACCTCACGGGGCTGTCATCAAG

Following is a LOCI 15209 genomic nucleotide sequence that includes the LOCI 15209 SNP "MRP1-AE" (SEQ ID NO: ).

TGTTCTTCATTGCGTAATGTCCAGTGCATTTTATAAGTTAGATTTTACTATTCTGTATCACATGCTTCCTTCCAGTTATTG

CAAACTGATAAAGTTTTACTGTTGTTTTTATCTAATCCACTTTATTGCTCAAATCATTTGCCATTAAAATACAAATGGCTC

TTCCCTAACTAAAAATTAAAAATGAAATG [A/-

]AAAAAATTCAAGCTTCTAAAGTAAACGTTGCATAGTAAATATCGTGGTATATATACTCTGGTTTATCTTGCTGAAAGGCG

TTGCTCTAGGGGTGATGAGTTGAAACCCAAGGTAATTTAGCCTGAGATGTGTTAGAAGAACAACTGACACGCCTATTTAAT

AAGTGTTATAGTCCCAGTTTGGTAAGTAAATATTTTCCACAGATATTTATAGTTTTTTTTTTGTTTCAGGTAGTCAAGTGA

AAAAATGAGCTTCATCTGTGGATTGCAGTCTGCTGCTAGAAACCATGTTTTCTTCCGATTTAATTCACTGTCTAACTGGAG

AAAATGTAACACATTAGCATCCACCTCACGGGGCTGTCATCAAG

[0315] Following is a HRMT1L3 genomic nucleotide sequence (SEQ ID NO: 6).

HRMT1L3 REGION GENOMIC >12:3493701-3577000

1 tctggttcct ctgaggttgg tatccggttg gctcagtgtc agagccctgg ctgggctggc

61 accaggaccc tctggctcac cttgtggggg atgccagcac cagattgctg ttggggtgtg

121 gctggcattc gggctgcaag acgtggttta gagaggggtt gctcacccag gcctgcagag

181 cctctccaaa tccatccgta cttccactga agatgtccaa tataagcggg tcagggtcac

241 cctgYctcca agtggaatgt aaatacataa cacRtggagc cttttttctg agtgtgccag

301 catcccacat gtgcccttcc agttcactct gcacctgtct gcaccctgct ctggagaggt

361 ttccttgcaa agctgacctt tccggctggg ttctgcctgt gggcgacagg agcaccagtg

421 ggagggcaac aggagcacca gtgggagggt gggggaggga ggggcattga ttccctcggc

481 ccctccctat gggggtcact gtcgacctgc tctttccccg acctgaaact ttcgtgtagc

541 agaccccata ctccttcatg gcttctgggt tccagtaact tctcccctct tgcctcctac

601 atctaggggt catcctggag ctcctctctt accaatccca ggcaactgcc actttgcttc

661 ctctaagcta tgttgacaaa cagaaattat ggatgccatt catccagcac ttgctatgtg

721 ccaggcactt ttcgaagctt tctacatgaa ttctgtcttt taaatcctaa aaaaatcctc

781 taaggatata ctaatgtctc caatttacaa cagggaaact aagacacaaa tgggttcagt

841 aaatttccca ggataacaag gtttcaaaca aaagcagtcc tattccagcg tgcactcagc

901 atagggtctg gtcaacaggt gctggctgtg gttttgattg tggtggcggc tgctcattag

961 gattgctagc tgctcacatg ttttggatga attcagaaaa gcagacctgg tttgcaaagt

1021 taggtccacc ctccacctgc tcactggtgt ggtccctggg ccagtagcat cagcgtcacc

1081 tgggaacttg ttagaaatgc aaattgtcag agggatagcc ttaggagata tacctaatgc

1141 taaatgacga gttaatgggt gcagcacacc aacatggcac atgtatacat acataacaaa

1201 cctgcacgtt gtgcacatgt accctaaaac ttaaagtata ataataataa aataaaaaaa

1261 aagaaatgca aattgcctcc ccatcccaga cctgctaaat cagaacctct ggggacgggg

1321 ccagcaatct gttgtccagg tgattgtgga catgctggct tgacagccac cacactgcac

1381 agaacccacc cacatgctct gtgagtagaa gcacattgct ttcctgcagg ggtatttacg

1441 gtctctgcac tctgagcctg gtgtggttga actagcaggg cgggccccat tctctagctt

1501 gctctgcgaa acaggctgcc ttgacaccca tgcattgtcg ttagtgctgg cagttcctat

1561 ttcccatctt ctggtgactg tggccagcca gaagcccagg cttccctggt ggttggtttc

1621 tcaggtctgt gtacctattt gtcctggctc tgtcttttgc tgctcttctc cctgatgaat

1681 ttaactttac ctgtaaggtc tctggtagct ccagcttata gtttggcctt gtgKataaag

1741 tatccgccaa tagttgaccc agctttcttg ggctctggag tgcccaacct ccttctgaga

1801 taaagcaagg cagggtgggc cattcacatg gtggagcatc tcagagcagc attgagtggg

1861 gccagggcca tgcttgggca gttgaggaag cacttttctt taccataggc cctagggctc

1921 tctggtatgg agctacctgg catgtggcag actgggtctc caggattggc ttcagctgct

1981 ctgtcactgt gcttctctgc tgttttcttt gcctggtccc ctcttggtga tttgttaagg

2041 ggttcattca ttcattcatt cattcattcg tttgttcatt tactcatgca ttgcattcaa 2101 caaatattta ttgaatgttc actcagcgta agagacagtt ctataaactg ggattatagt 2161 acagaggagc ctgatgctgc cagcatttac agagctttca ttttatgggg gaaacagaca 2221 ataagcaaat atatgaagtg gtgtccggtg ctgaagaaag ttctgaagaa aactaaagca 2281 agtaagaaaa tagaatgtga tggaggtggc agtgtttgca gagagggtaa tctggagagg 2341 gcattctgaa aaggtgacat ttgaataaag acttgagtga ggttaaagga aataatgtat 2401 acagtggtcc atttccaaga caaagggcct tgatttggcc taggtcagca aactacagaa 2461 gaaacaggat atactaggcc cctgcttcga tagccgatgc ttgtttgttg gcctccccct 2521 ccccaccttc cccctcgccc cttagttgcg ctcatccaaa ccaaaaaact ttcatctaaa 2581 ataagaattt accagtctgc aaaatagctc acttttgtcc attcttatca gcctgcccag 2641 ctacttaggt catatgtcaa atactttaag agcccctgag ctaactagga ttgcaatgca 2701 ttgtgggctg caacaaaatg cagcaagaca acctaaaaac aacaacagca acaacaaaaa 2761 caaaacaata aaacacctaa agcccctacc caacaatcaa taggcaacgt ccaggaaaat 2821 tgtaacccca tagtacccag cctgtgagga actgggggag ggacctgtgc accaggggat 2881 cagttgcttg ttgaaactgt tctgggtgtg cccgctcatc agacacccga tcttgtaaaa 2941 tcgtcattaa aagtctcact ttcgctgttc tccgggtctc tgagtccatt ccttgggttt 3001 ggatgggtga ctttgtttct cacaacctgg tggcccgtac agagatctct gtgcccgcgt 3061 ggagtgagtc tctggccgag aggggagaca catcccactt gatttatgtg gcccgctctg 3121 tccaggtgtc ctggctcccc acagaagcca tagacaaacc caacactgtt attcaggaga 3181 cagcgaaagt gacacaggga gaaaagcagg cactgcagca accaggcaag ctcatgcatg 3241 agctaaggta ggaaaattga actataagta ctgccttggt ggttgggcat ctttggaggt 3301 cttgggggtg gaagaaacct ccggtaagcg gggctgagta cacagaggtg tgcaagaaac 3361 ctccattgag ggaggctgag tacacaggga aaagctcaaa cacagaaacc agctgaaaat 3421 gagaaactga aattctaggc ctagggaaca agggaaagag ggaacttaaa aaccccttct 3481 aacattctcc cagatagtcc gctggggaga atgttgcagg tttaaaggga taatcctcaa 3541 accagggaaa aggaaaagca aaaaataata aagtattgct gttttgtctg gcctaaagag 3601 cctatttgtc agccttcagt cttttggtct aagtttggct cagataagga ttgagtgtgc 3661 gaagctttaa ttttctatgt gaataataaa atcccatccc cacaagagga gatgggttat 3721 gctctttgtt ggattagtga actaacccac atgtttcccc ttaaagagaa aaaaaaaaaa 3781 gcatagtaaa cagcccttgc ccagtgaaaa gccctgggat tccccaacac gcttgccccc 3841 ctcaccatac atgtcacaaa gtagaggaca gggagactgg gggcaacagg aaagtcggag 3901 gaagaggaat ctgggggtca agaagaagct aaacccaatg ctcccttaaa tccttaccta 3961 aacttgaggg aagaattaga acaacgtgag aaggacatta agaatttccc tMttccttgt 4021 aaacagcagg catctaatgt gcgccctcct agagaagcct ctatgggaca gggaagagtt 4081 aaatttgtga gtgtacctct aacaagtact agagttagga attctttttt ttttttaaaa

/ 4141 aaaaggccac tctYggaaaa tcccctcagt ttaacaaagc agctaaatca atttttaaaa 4201 cccaattttt gtacctgggc taaggtaatg tcaatcgtga atattttgtt tactggggaa 4261 gagaggggaa taatgaaaag ggcagccata accatttggg aaaaacggca tcctcccagg 4321 caaggactcc tgccagctga gcagaaattc ccaaatgcaa atcccagatg ggataacaat 4381 aaccccagaa atcgggccca aatgcaagac cctagaaagc taataataat taaagggatt 4441 caagagtcca ctcctaaaac acagaatgtc tcaaaagcat tcaaaatcca acaagaaaaa 4501 gaggagactc cctctgtgtt tctgcaaagg ctcttgggga ccaaataaga aaatactcag 4561 gRttaaatcc agaaacccag tagggcaagg ccttttaaag gttaattttg tgactaaaag 4621 ctgggctgat attactaaga aactgcaaaa aattaacaaa taaagtttta aaaaattaaa 4681 aattactaaa ggaagctcaa aaggcttttg taagaagaga aaaaaagttt agctgctgac 4741 cctgaaggca ggggagagcc ggccacacag ctatatgtgg aagctggctg ctagaaagct 4801 gttaatagaa gtgactgcta aatctttgtc attttggcag aactgtccgt ctttgcagac 4861 ggacagaggg gagccagggc ccagcacggc tcagctcgtg gccagagaga gaaagaagaa 4921 aaaactaagt gtaagggaaa aaggaaacag ggaatgacag agagagagag agaaaaagaa 4981 aataagcgag atagagactg gaaataacag agaccaaagg gagacactga agatgagact 5041 ggggagaaaa ataatggaaa aggaagaaag agtacaagag gaagtgagag gatgcggaga 5101 ggttggcagg gctgggggaa ggttctagag gctcaagcaa caaagaggtg ccgggaaagg 5161 atgcagtgtg gccactgagg cgggacaggg cccaggaact gggggatgca agtgagaaag 5221 ggatgtggag gagagtttag gatcaggctg tttgaggaac agtgggttgc ctatggcaaa 5281 gggtagatgg ctgtttgtga ggtgggggta gaaagcattg aggatgtgga agggtaaatg 5341 gatgagatga ctattaaggt tttgttgttt tactgagaag ctgtgagtcc accaggggca 5401 gctgtcagta aggctgcaga aaggctgggg ggctacataa ggaagatcca aattagggtt 5461 gtaaactcca aggactacag ggccagcaaa tggtgagaaa aagggctgca gggttggatg 5521 gggactgtga ctaactcaag agggcacacc ctgttaaagg ggccatggtt gctcggctgc 5581 tcttacagtg ccagccctgt gttgccaaat tgtcaacaaa atttgggaaa catctaattt 5641 tttaatgtaa aatataagtt ttaaatgctg gtgatcagtt caaaaatctt aaaaacccaa 5701 tacaggcgaa agaggatgcc actttgccat ctctgaaata gagagatctc atgctgggga 5761 aaagtctgcc gagacgcttt gaggtgggtt gtatgaaagt ttcccagagc caggctgggc 5821 caggggagga tccttgcagc tgaggaggag gaaaagccac tgagtcccct cccagagtgg 5881 ggacaaaccg gagacccttt gcagttgctg ggtcaccaga aggggcgatg taaaatacaa 5941 acagtgcatc tctcggcctg tcgggaaaac caacRgtgcc ttcaaagcaa agaaaaggaa 6001 aggagagtga agccagggat gcctttgctc atgagagtgc ccatcaggga aggagccaca 6061 ggctgacagc tcttcaaacc agcggctctt ggcccaaagc cagacctagc aggacccagc

6121 caaaggcacc ctgggagccc agctgttcag tcccttgcct ccccacgttt cccagtgcac

6181 cctggaaagg tgcctaacct aactccagcc agtttcttat aaaaaggaga ggagaataaa

6241 aaggcatcaa actgtaactg tttaaatatc ataaaatatc aaactaaagt taaaccaaac

6301 cttaaaaaac tccactacat aatggaataa ggctgtttgt aagtgggtca tcccaagtaa

6361 tagatggtaa aaaaacacaa taactatgct gtcatcaatg aaaacaaaca atccttatgt

6421 aaaaaaggta aattactcaa taattgttca gcccaaatct gtaaattata tgctcttagc

6481 caggccctga agctcctata aggccacaat gacactatat atattaattc caaatatgcc

6541 tatggagtaa tacacacctt tggaaaaatc tggacaaagc aaggcctaat aaatagcagg

6601 tggaaagatt tggtatgtgg ggaactggtc aaacaagttg taaaaagcca cctgctccca

6661 gcaaagatag ccatagttca tgtaaactgc catcagaaag gaaacactat agaagcttta

6721 gggaacaggc ttgtggataa agctgctaag caagtctccc tggaggaaga agttaaactc

6781 cggcctaatc ccagatatcc caaggtggta ttaaaacccc aattttctaa agagaaaaag

6841 gaaaagctgg gcaaaatcag ggccactcaa actgaggatg ggacatgggt gctccctgat

6901 gggagagaac taataagcaa acccataata agagaactaa caaacatcca ctctgcataa

6961 gggaagtcac tggggtcgcc caggccatgt gtgatccaat actcaagaat tatgggtggg

7021 ccaggcatgg tggctcatgc ttgtaatccc agcactttgg gaggccgagg caggcggatc

7081 acttgaggtc aggagtacga gaccagcctg gccaacatga cgaaaccccg tctctactaa

7141 aaatacaaaa attagctggg catggtggca ggcacctgta atcccagcta ctcaggaggc

7201 tgaggcagga gaatcacttg aacccggaag gtagaggttg cagtcagctg agatctcacc

7261 attgcactcc agcctgggca gcaagagcga aactccgtct caaaaaaaac aaaaacaaga

7321 attacgggtg tacgggaatt gatacccttg ctaaacaagc gtgtgaaaat tgtgtaacct

7381 gacaaaaagt aaacgaaaaa atggtcagaa aacaaactac tggagaaaga cctcctgagt

7441 taaggccatt tcaaatcatt caagtaaatt ttacaaaaat gctcaaaata gggagactaa

7501 agtatctgct ggtaatggta ggccacctct tcagctggat ggaggccttc tccctcccaa

7561 ctgccactgc cctgaatgcg gtcaaaataa tcttaaaaca aattatacct aaatttggcc

7621 tggtagaagg tattaattca aacaatggga gcgactttaa cctcaagagc actaagggga

7681 attacggaaa gtttacacat taaatgggat taccacaccc cttggcatcc ctcttccttt

7741 gaaaaagtaa aaagaataaa tcaaagtctc agaaagtata ttactaaact aatcttagaa

7801 actaaaatgc ctttgaccaa atgtctccca atagcactcc ttaggattaa gacagccccc

7861 acaaaaaact ggaaattgtc cccttacaag ttgttatatg gactcccgta tttaggtagg

7921 accactaact ttcctactat aaaactcaaa aaccaattta aaaaaaaatt gtatactggc

7981 catatcctcc accctgtcat tccttaggtt aaaaggactt ctaactcaaa ccctgtctct

8041 gaagttcaca gttcaccact tccagcctgg cagctcagtg ctaattacca cttaaagaaa

8101 aacaagctca ggccgggcgc ggtggctcac acctgtaatc ccagctcttt gggaggccga

8161 ggtgggagga tcacaaggtc aggagttcga gaccagcctg gccaagatgg tgaaaacaca

8221 tctctactaa aaatacaaaa attagctggg cgtggtggtg ggtgcctgta atcccagtta

8281 cttgagaggc tgaggcagag aattgcttga acccaggagg cggagcttgc agtgagcaga

8341 gattgcacca ctgcactcca gcctgagact ccattaaaaa aaaaaaaaaa aaaaacaagc

8401 tccacccaaa ctgggaaggt ccccatcagg tgctcctaac caccaaacca ccgtgcaaat

8461 agctaaacaa gggtaaatac attacactag ggtcaaaaaa ctggaaaaca aacaaacaaa

8521 aaacaaacaa acaaaaaaaa acagaaaaaa atgaaacaaa gggaaaaggg taaatgggaa

8581 gtgtataaat cacctaagaa acccttaaag ctaactctaa ggaaaaccta aaaggaagct

8641 ataagcaggc tccgtcattg ggggtggatg cggttagaat taattctact accaggggta

8701 agggggttca caattattaa atggagcctg atagaaaaaa aaaatcccat caaactaata

8761 gtcagcagaa ttaaaacctc caccccccaa accataaagt tcaatgcctg ccaagtctta

8821 cagtgtgaaa atttaggaaa ccaaaggcag ctgtcacaag cgaacaaata tctatgtcct

8881 aaaacaggtt gctattggga aaagccctgt gctagctgaa atggggtctg gtaaaccacc

8941 caatttcaag gctgggtgag tcactcttcc aaaaacaaac ccttaaaaaa gaaaatacat

9001 ttgtataagg gccctacgcc acctaactgt aaaaatttag aatgcaatcc tatattaatt

9061 accataaaca acccagctac tctaaaccag gaagcttgga ggtatggatt aggaataaat

9121 atctcaggaa gggatcctgt aggacggtta gcttttaggc aagtcaccat ctccacccca

9181 agcccaccca ggattactgt cactccccat cccactactt cctttaaccc accagacaac

9241 cctaagagag taaaaataat taaaataact aacttaaggc aaatttaaaa agttaagact

9301 gaatatgggg gtgtaaatgc ctgggttaaa tgggtcaaat tttcaatact agctcttaat

9361 aagagcgact gttacgcatg gtctgctggg cggcctcagg cacagggtag ttctgtttcc

9421 cctgaaatgg aataccaatc ccaaaggcag gcattgcatg ttggctctgt actaaaacag

9481 aaatgcatgg ggaaataaga cttacaaaag cctatcattg ctctttcctg ccttacgaag

9541 gtcaagttct agagcaatcc ccttgttctc catagggaat ataaaccact ccttctgcct

9601 ctctatgcag gggcaaagtt caataagcct atgggaaaac tcccaacttg tacacacatc

9661 ctaaacgtta ctgatgagtc aaacaaaggc gactactcgg ctcttcatat gccctgggct

9721 aatgtctggt ggtactgtgg gaagagaaac ctcagtaacc tgttagtatc caattgcacc

9781 ggaacttgtg ccttacttag ttcaactggc cattccattc accttgacat tccataaaaa

9841 tccccaagaa tccacatggc caccaaaggt ggaaaaattt aataagttct tttaattcca

9901 acatttatgg taactcaata ggagttccta atggagtatc taataaattt aaaaacgaaa

9961 gaatacaaaa ataaatgtgg aaatgggaac aataagagta aaaagaaaaa gaagaaggaa 10021 ttaaaggaaa caacgcatac agtggtccat ttccaagaca aagtgcctta aattggctta 10081 ggtcagcaaa ctacagaaga aacaggaaat actaggcccc tgcttcgata gctgatgcct 10141 gcttgtcagc ctccccacct tccccctctt ccccgcccct tagttgccct cacccgaacc 10201 aaagaagttt agtctaagat gagtttacta gcctacagaa tagcttgttt tgtgggttct 10261 tatcagcctg cccagctact taggtcataa atcaaatact tgaagagccc ctgagctaac 10321 tagaattgca atgcattgtg ggctgcaaca aaatgcagca agacaatcta aaaaaaaaaa 10381 aaaaaaaaag cacctgaagc ccctacccaa caatcaatag gcgacatttg ggaaaattgt 10441 gaccccatgt gtccagtcta taaggaaacg ggagagggac ctgcccacta ggggataaat 10501 tgcttgttaa aactgtgctg gatgtgcttg cctatcaaac acccaatctt gcaaaaccat 10561 cattgaaagt ctcgctttca ctgttctcca agtctctgag tccattgttt gggtttaaat 10621 gggtaagttt gtttctcaga aggtgaaaga gtgaactatt caaatatggc caggtgcagt 10681 gcctcatgcc tgtaatccca gcactttggg agaccgaggc gggtggatca cctgaggtag 10741 gagttcgaca ccagcctggc caaaatggag aaaccccatc actactaaaa atacaaaaat 10801 tagctgggtg tggtggtgca tgcctgtaat cccagccact taggggactg aggcatgaga 10861 atggcttgaa cctgggaggc agagattgca gtgagccaag accatgccct cgcactccgg 10921 cctgggtggc agagtgagac tctgtctcaa aaaaaaagag aactattcaa atataaggga 10981 aacagctggt gcatagtctc taggtggaaa cccttagttt gtgggtgtca gatagcagaa 11041 taaagatcag ggtgacagag gctgaagagc aggagggggc tgggaaagtt gcagggcctt 11101 gtgggtatgc agaggataca ggagtttgag gatcaaagtt tagaactctg gagcactgag 11161 gggatggcca ttgcattctg aatcttccta cttctccatt tagcatatgg ccttcctttg 11221 cttctagaga ttgccttttc taggcttcag gacccacaga tattccttgg gaaaatggtc 11281 ttttagactt gttcttctct ctttcccatc attattggaa tatgctttcc ccctcctttt 11341 aggagtgaag aaacctcatg agtgagttca cacttagatg tttatatgac aagtaaatgc 11401 ttaaaagtct ttgatttgag agtttgggaa gtgatagaaa tgatagaaag ggaaaggctg 11461 tgtctagatt tcacaggcct taagtctaag gattgctgat ttcggtggtt taaaaccacc 11521 aaaataaata catttgtcta tttctccttg tgattctatc agattttttt ctccaattgt 11581 tttattttga taaaatacac ataacataaa atttaccatc ttaaccattt ttaaatacac 11641 tgttcagtgg tgataagtac attcacattg cagtgcaacc atcaccacca cccatctcca 11701 gaactctttt cgtcttgcaa aactgaaatt ctacccatca aacaccacca acccccattc 11761 cctcttccag cccctggcaa ctactgttct gctttctgtc tgtataattc tgacgatgct 11821 accttttata ggtatagtct taccgttttt gtcttttcgt gtctggctta tttcacttag 11881 catatgtcct caaggctcat tcatttgtag catatgtcag atttttcttc ctttttaagg 11941 aagaataata ttaaagtgtg tgtgtatacc atattttatc tattcaccta tcaatggaca 12001 cttggtttgc tttcccattt tagctattgt gagaaatgct atgtgaacgt gggtgtacaa 12061 atatctcttt aagcatgtgc tttcaattat tttgagtata tatctagaaa tggaattatg 12121 ggatcacatg gtaatactat acttaatttt ttgaggaacg gtcatactgt tttccacagc 12181 agctgtgcca ttttacactc tcaccaatgg tgcacaagag ttccaatttt ccactctctt 12241 acaaacactt gtcattgtct ttcttttaaa aaatatatat tagccaactt ctgggtgtga 12301 agtggtatct cattgaagtt tggatttgca tttccctaat tattggttct atcagttttt 12361 gtttcatata ttttgtggct ctttcattag atgaataagc ataattccaa acataacaat 12421 tggaattgtt atgtcctctt gattgactcc tttatcatta tgaaatgatc tttttctcag 12481 tgatagtatt tgttctgaaa tatacattgt ttgatattaa tatagctatt ctaggtttcc 12541 tttcatcaga attaacatgg tatatatctt ttgtcatctt tttactttta agcttttatt 12601 atgttaaagt aagttttaaa tagaatggca tatggctgtt tgtaaaatct aaagtgataa 12661 cctctaacct ctgcctttta attgaagtgt atagaccatt tacatttaat gtaattattg 12721 gtgcagttgg gttcaaacct accatcttgc tatttgtttc tctattactt atctgttctt 12781 tgttatgctt atcttctttt tctgcatttt gggggcaatc tataactttt tgtactttta 12841 caaagtggcc acattagggt ttatggtata tgtattgaac ttatcatcat ctaccttcaa 12901 gtaatattat agcaccttat atatagtaat ccctcttagc tgcaggagat ataatccaag 12961 acctctagtg gatccctgaa atcaaagata gcactgaacc atatatgtac tatttttttt 13021 aatctgataa ccaagacagt taagctacta agtgactaat gggcgggcag catatacagc 13081 atgaatatgc tggacaaagg gatgattcat ttcctcggta ggtggaaagt gagatgatgc 13141 aagatttcat cttactactc agaatactgt gtaatttaaa acttatgaat tgcctacttc 13201 cggaattttc catttaatat tttcagacaa tggttgatat ctggtaactg aaaccatgaa 13261 gagcaaagcc atagataaag ggagactact gtatagaaac cttcaacgat atatcaccat 13321 tcctcccctt ttggcctttg tgctattgct gtcattgatt ttattcctat gtatttataa 13381 ttcttacaag atttttaaaa aatttaaata gttaatgatc ttctaaaggg atttaaataa 13441 taagaaaaaa agccttttat atttacacat agagttacca tttccagagc acttcattct 13501 tggtgcatac ccagatttcc acatggtatt gttttccttc tgtagtatgc gcctgtgaat 13561 gataaaatct ttcagttttt gtatgtctct aaaagacttt actttaccgt catttctgaa 13621 agatattttc actgggtata gaattctaag ttgacagttt tttcttttat ctttttggtc 13681 ctctgaagat gttgctacct tatcttctag cttgtgttgt ttcttatggg aagctggctg 13741 tcattcttat cttagttcct ttgtaatata tctccccatc cccctctacc cctgccactt 13801 ttaagatttt ccatttatca gtggtgtaga gcaatttgat tatgtacctt ggtatagttt 13861 ttttactccc tcacgattct tgtgttcagg gtttgttggg gttttcagat ctgtgggttt 13921 atgattttca tcaatttgga agatgaaact ctaaagccgt atttctttaa atatttttgt 13981 gtctcctctt ccttcaggtg ctacaattac gttcatatta ggctatgtga agttgtccca 14041 cagctcaatg atattctgtt taacttttgt tcagtatttt tttctctgtg ggttttttgg 14101 atgatcttta ttgccttgtg tcaagttcac taatattttc ttctgtaatg tctaatctgc 14161 tattaacctc aatcagtgta tttccttttt atttcacata gtttttatct ctagaagttc 14221 aatttcggtc gtttaaatat cttccatatc tctacttaac atgctcaatc tttcctccag 14281 cttcctggag gaaatagaat acagtttaat aagtacttta atgtcttata tactaatttc 14341 atcatttgta tcatttctcg gttcagtttt gtatgattga ttttttttct tctttatagg 14401 tagtattttc ttgcttcttt gcaagcctag taatttttga ctagatgcca gacattgtaa 14461 attttacctc attgggtgat ggatattttt agatatttta tgcttctaag ctttgttttg 14521 agatgcagtt aatttagttt aatcctttta gatcttgctt ttaagctttg gtgggatttg 14581 aactatcttt ggagctaatt ttccactatt caggggaaca acaacaaaac acctcttctg 14641 agtattcatg aattatgaag tttttactct ggctggggag agcaagaact atttctggct 14701 ctgtgagccc cacagagaag tccctgtgtc ttttcagtag ttcttttccg aggctgtggt 14761 agttttttca catccatggt ttgatcagtc tcagctgaag gcttgcaggg aactctttac 14821 agatctctga aggctcttct ctgtatagta ttttaatcta caagactctg cattgcaaac 14881 tttatctgtc ttgctgtccc cagattccca ccttcaactg agagagatta ctgggtctgc 14941 ctgggttcct gttctctgta tggtaggctg gataatcctt ctaggcagta agctggggta 15001 atcttagggt ttacctcatt tatttgtcat ctctcaggga tcatggtttt ctattgccta 15061 atgttcaata tctcaaaacc tattatttct tatcttttat ctgttttttt aactcattgt 15121 tgggttgctt gggagtgctt taaaaaatcc agtttcttgg aatctgtatt ggctaatatg 15181 aggccacctt tggagcagac ccgcatatta cccagtggct gacgttattc cctctctagc 15241 cagaatgcca gtattttcag tgagtgtgta cattggaatt tctggttaaa gaagtcagtc 15301 acttcttcta aaaatatgag tggaaatata atcatttgga gtagatgggt ttgctagaat 15361 taggtggaag atgtctagaa agagtctatg gaaaccaggt gagaatctag attaagttgg 15421 tatggctatg attttggcca gcaacttgtg attttctttc tctcttataa catgattttg 15481 tagttcattt ttctccacct tcagctcaat ggccagatga tggagcctga gaatctatga 15541 ggagtcagct cctggatcct caccagttat gctctatggg ctgaatcagt cagtcagcgt 15601 ctctgaacca tggcatcatt acctgcagag agggcttgta ctacacgggt gcaaagagat 15661 ggttggaaaa tgtctaacaa atacacttag atctgtattt gaagccactt gtagtgtgtg 15721 gaattatgga tgcttaataa atgcattcta tgtttgcaag atatgttctt ctcctagaaa 15781 tctccttatc tcccaggaga taagacactt cttggtaaag acattttgag taccactgaa 15841 ccctccaaag agtattgagt attattgaga ttctgatgat tattattccc aattttgctt 15901 ttcttctgcc acctctctgc cctctcaagg gaagtgaatg ctctctgatc acatggtggg 15961 aaagggcctc cttcactcga ctataataat aaatttatga agggcaacat tcacccagtt 16021 gaagtgtaag tgtaccatta tcacatcttt cttatctagc tttatactaa gtattaagag 16081 ggaaacacag acatataaaa tctggttact agtctgaaag aatttacttc ttgttgtaga 16141 agtaacacct acaattgtga gataatcttc aggagacaat ttgccagcaa aataaatagg 16201 aacatagccc atagtttcag ataagcagat gccataggag gtcaaaatag gagcaggaga 16261 gacccaagca tcagcggctg gagaaaatga ctgattttca atgatggcta ccttcctaaa 16321 gatatcaatc ccataatgcc cagaaagctc agaggacgaa gggcagaacc aaaggcttga 16381 gagtgcacaa tgtgtaaggg aggggccagg gccaagcagc cagcagaaca gggctctacg 16441 ggcagccaaa gccactgtgt cctgtgccac gaaaggccca gagagcatct aaagatagca 16501 ccctggcaca gagtcatacg gcgagagcgg gaagcctggt actcctgtac cacacgctcg 16561 aatttcctct gaatatttac acgctcagcg tcttccagtc atcaccatag ccccacaaaa 16621 gaggcgggac agaaaatcat tgccatttgg agaagaggaa accgaggata gggaaggctc 16681 aatggccttt gcacagtgac atgaacaggg aaggagagaa gcaagtccag aacccaccgg 16741 tgctgtttct ggctgtgtgc ctacgaagcg ggtacaggga aaactcctct gaggactcca 16801 gcctggggta aagagagtca tgaacatagc ataggtccca cagggatgat ttgacccaaa 16861 tctggaacta aaagtgtagt ctaactccag gcaaggtgag ggtaagagag gacactggct 16921 gtgtgtttct acacatctgc ccataaaaga gagtggagag ggaagccagg gctccgtaac 16981 ccccttcaag tcaaaggagg ggaggaggct cccttgcctt ggggagggaa gagggaggaa 17041 gaggagggga atgcataggg aagtctgctt ttaagcccat taatgaggaa gagccaagca 17101 tccaattaac ttgacatctc ttgcagccaa aatatctgag gatataagaa gcgaatttaa 17161 tatgtggagg cttgggagac aagtgactaa tagtggaaaa cagccccagt ttatttaaaa 17221 aataggtcag gcccaacaaa tccaatagat tccctctcag cacttacgga tccaggagac 17281 agagggagtg ctgtgtgggt gcaatgccat tttgatttga agcagacatt gttgttgtac 17341 caccaagaga cagccagggc tggcaggagg cgcctgtgca cagcatgcag ctgctgaggg 17401 cggccttcgc gtcaagcgtc tcagtgaccc tggtcaggac agcgagtccc taccagtgac 17461 cggcccaagg tcacgaagcc tgaaggtggc ggcgcccaca cccaatccca gcccctctac 17521 tctcagagct aaagtgctct ctgtggcctt gggtgcctct cttccagatg tccttggccc 17581 ggctctggga atcttggttg gctctgagat ggcagcacca ggctgccatc tgagagctat 17641 ggcagagctc agggcttcag cgaggaagag agaaggcctg aagctgtcct cggcactgtc 17701 aggacagggt tcctaggcac cagctggaga gcctgttaac atgcccagtg ttgggtctca 17761 gtcccaccct gatttcattg gtctgcggtg ggctggagat ccaccagcga cggccgacat 17821 ggattataaa acagaaacac tgtttgaagt cggagcccag gttgtttctt tcagaacgtt 17881 aatttctaga gatgtttata gatctcagga aaaagtgtgt cacagccata aatgtgatag 17941 tagtagatgc cctaattcct cttagaaatt tatattatat aatatttata taatatattt 18001 aatacatata ctataataaa atcatttatt ttagcatttt aaaggcttaa aagtattgca 18061 attaagaatt ctctttatgt aatcccagcg ctttgggagg ccgaggcagg tggatcacct 18121 gaggtcagga gttcgagacc agcctggcca acatggtgaa accccgtctc tactaaaaat 18181 acaaaaaaat tagcctggca tggtggcggg tgcctgtagt cccagctact tgggaggcta 18241 aggcaggaga ctggcatgaa cccgggaggc agagcttgca gtgagctgag atcacgccac 18301 tgcactccag cctgggcgac agagtaagac tccgtctcaa aaaaaaaaaa aaaaaaaaaa 18361 aaaaaaaaga gctctctctt tagcttatct gcccaaacct acttgccatg gaaccttttt 18421 ctaggagtac caattataca gtatacaatg tgggaaaatg ttactctaga ccagtggttt 18481 tcaaacttta tggtgtatca gaatcacctg ctgggacccg tcccaaaatt tctgattcat 18541 tggtttctgt ccttcaaggc ctgggaatct gcatttctta ccagtcccca ggtgatgctg 18601 gtggtctgga gaccacactt caagaaccac tgccgtagac ccctctgcaa gccctggctc 18661 agccgagggt cctgggaggc ctcccagagt gggagggtgg agactgagag cagtgggcag 18721 caggagctaa gagaaggggt ttccaggaaa cacagccttg agaaggcttg actctaaggt 18781 aagaaaaccc tatgtaggga tgggctctgc caagatccca gagttagagt cagagattct 18841 ataaaacagg gggttccaaa tgggggacag ccgaccctct gtgacaggca tcagtggctt 18901 gcccccaaca tccaggcctg gaaaaggcag atctggagag cgtctgtgcc tacgaagcca 18961 agtcttgtga agggcatgag gcagacgact gaagaataaa ccagagcaag ctggggagcc 19021 cgggaggcca catgcagaag acaacaccgt ctcgcaggac tggcaacacc tagatcaagc 19081 ttgtccaacc tgcagcctgc acaccgccca ggatggcttt gaatgtggcc caacacaaat 19141 ccacagactt tcttaaaata ctatgagatt ttgtttggat ttttattttt tagctcatca 19201 gcaatcgtta gtgtatttta tgggtggccc aagaccattc ttcttcttct aatgtggccc 19261 agggaagcct ggacaaccct gaccctcctc ccctttgccc ccagactctg ggcttccagc 19321 cccgagggta agaagcagca agctagagct acctacccta gcacagtaca cccctctgag 19381 ggggctgact tcatctgcca gccccgatga taagacaggg gtgcaggaga gtagagagag 19441 ggtgcatgta gggctgtctt ggccaaaggc aggcaataaa gctgtacttt tgctttctta 19501 ggtgatagga gaggtcccaa tgcccagcag agcccttgct tgtcttgctg ctgcctgaca 19561 tttcacataa gaatgttctt tttttctgca aacctctggt ccctatctaa aggcaggcag 19621 atggttctgg aagagctaac cctttgtgta attatgcaga acgggagcca cagcttagat 19681 cacagcctgg tgagtaaaca caggttgaag agaggtgtgg tgagtgtcta agggcgacac 19741 tgggcagagg ggctggcacg aaggtgggca aggagggaag aaggtgaagg cggtgggcaa 19801 aagagtgggg tgaggcccag gctggaagcc tcctgccacc cctactctgt cccctcccac 19861 tgcgatcctc tttcttccct ccgtgggccc tccaggccag gcaggcggct gctgaggaca 19921 gacgactcag gttagaaaaa gctctcttga catttggaga acagagcagg atttggctcc 19981 tctagtggag cctcttgttc tcagggaaat cattttaaag cttgggctgg tgccagcagg 20041 agccatttat agcccaaagg gcttaggttc actttggctg cctggtgcag agagtgctgg 20101 cttccctctc ccctctgcag gctgccttcc cccttcagat gtccagcacc ttcactctcc 20161 ttccttaaag cttctttttc ctctcctcta ccacctcttt cctattctct tggaggttcc 20221 agttccagat ccacctccgg acctagattc ccctaggtga gcctaaacaa attcctttcc 20281 ttctgtgggc ctcagtctct ccatctgcac cctgacacct attgtctgct ctctttaaac 20341 tctgtcacct tggagaggtg cctgcctgtg cctacctcca ctgaagcgct ctcctctgtc 20401 tagttattgc ctgttgactc tctttctgcc ctcaacactg ggcttcctgc ctgggccagc 20461 tgtgttaccc ttttctgagc acagggcctg gctcctggca gtagctcagt taagcttggt 20521 tgggccgaac tgagctaacc atggcatcag tttcaagagc acaggttttg gcataaaaca 20581 gatactggtt gacatcttgg ctgtgctgct tgctatctct gggccctggc aaatgactgg 20641 actttgtgag ctttagtttc ctcatctgta aatgtcagtt actatgagga tttcacgaga 20701 tggtgtctat ctataaagtg cttggcgcag cgcctggggc gcagtgggcc cttagtcaat 20761 gttaggtctc atcaccatca tcatcctctg ccatctacct gcattttcaa gggatgtggg 20821 ttaggtcaaa catgctcccc caaatcccca cccctgcttg tggaaatccg acccaccctt 20881 caaggacgag ctcacaagct cacatgcccc ttcttcagga agccagcttc ctcctgtctc 20941 cagctctgct gcgtccataa cctttcatct ctgcatttag tgggcccgag gcctgttcac 21001 cccagtagag tgggtagact aagacaatcg cactttattt attagggaga aaaactgtgc 21061 tgaagctgcc ctgggtaagg ccagtctggg ggcggaacac tgtgttgggg gagtcctgat 21121 cagccgctgg cgtggtgagt cgaaggcaaa tcacaagtat tgacagtgga gggtgattct 21181 caccatatca gggaggcaga caacatcggg agacctccag caagtaacag ggccctgggc 21241 ctgggccttt ggacggaggt ggggaaagag caaggcaggg tgctttctct gccctggggc 21301 ccaagaaccc aacaggacaa ggctggaggc gatggtgcag aaacaggtac cagaaccgac 21361 tccagggcag agcaggcagg gccagacctc cagggtgatg tgggcacagg aaccctggaa 21421 gggactgggg gcactggaat gtccagtggg gagggacttg ggcacaggga gcaaattgga 21481 ggtgagaaag ctgcagccat gagcagacca agacgctgat gttgagagtc cagctgccca 21541 tccgagtgtg attccaaatc cttttgctga cttctcagac tatgtataca agattggagt 21601 ttgaaagtca ccttcactca gagactctgc ttgcctggtg tggcttaggg aggagttgag 21661 ccttctgact ttacagagga gaccactgtc atcccccaag acctatcccc tgtgctcctc 21721 aagtctcaag agccttcagt tgtggctgaa caatcatgta tatctcttgg agatgcatct 21781 ggattcctat aagtgttcca atttgcctgc ataggatcca tagaataccc atatgtctct 21841 tgtttctttc acagggctgg cacagtgcct tgctgttgta gaagttcagc aggtagttgt 21901 agaatttaaa agcatcaccc catgtagctg aatgttcagg gatcacaggc cacggctgct 21961 tcccacccac tcccagcctt cagggagagg gtatgcctgt cagccaatgg gcagagtgcc 22021 aggctgcaga ccagggtctg ggccagtcat ttatttgtcc ccatgacctg tggctattga 22081 aatgaatgcc cccaaatcca tgcatccttt tgcctcctgc atggcacacg gcagacactt 22141 cataagctgg ctgttgggga gagtctcagg gagccccatg gaaaagagaa ccttggaatc 22201 agagttgaat gacagcttat gggtgctgga ggcccctgtg accttgaccg tgcacaatgc 22261 ccaggccagc taggactttt tcctctcctt aatatattta aatggagtca atactggggt 22321 cagcttcatg cacacagcct tcttcagccc tagaggtgag gtgatctgca cagcttcctg 22381 agcagggtcc tccctggtgg ctgaggtgtg gagggcccca gccaggctgg atggaggttg 22441 actttgtttc ggagcccttg cttggacacc ggagtgcaat gctcgggcca cacatccttg 22501 gaggaagggc agcctggaag tggtggaaca atctgtcatg atcatatttt tgtgtaatca 22561 aacactcttc ccataatacc tttaatggcc gcatagtgtt ctattgtgtg gctacaccac 22621 agtttaatgt ctcactttgt ggaacatttc agttgactcc taccttttgt cactaaggac 22681 agcattgtca tgaaattctc aacagctaca tcattatgat gatccatgat tctcttctta 22741 tggtaaagtc cacagaactt caattgctgg gttaacggat ttgtgctctt taacacttca 22801 agtacatttt accaaacggc ctttctaaaa gtcttgacct attttcattc ccactagaaa 22861 tgtgtgaaag gacctatctc tctgcaactc ttacatatgc agagctgtgg ttgttttggt 22921 gggagaagag cttatctggt atttaaaagc tgtaagtttt ctatttgaat ttgaatttac 22981 ctgatttcta atgaggttaa acatttttgt tgcacatcaa cctgccattt gtatttcaca 23041 tgtacttgcc tcatgtggac agattatcca atcctttccc caatattaca ttgtgggtgt 23101 tcatctattt ttgtattggc ttgtaagagc tctctacgta ttaagggcat taacctttgt 23161 ctgccacata tgttaaaacg tacttctcgg tttatcattt gccttttaat tttgtttatg 23221 atatttattg tctggaactg cattaatgtc ttcttgctag acatcttctc ttatatgact 23281 caatgacatt tcaaactctg catatccaaa ttgaaattca ttatttcccc ccaccccaac 23341 ctgctctgcc tgctgactgg cttatttttg ttaatgtcac caccatttcc ctagtcaccc 23401 aggcttgaaa tgttgaagtc atctttgatt ccagctcctc tctcttcccc tacattttgt 23461 cagttgccaa agcctgtaga gtctatttct gcactttctc tggcaggcag cccctcggac 23521 accccagtag ttcaggctct cattatttct tgactggact ttgaacatag cctccaaagt 23581 tcatactttg cctctcttcc attcccttct tttccttggc ccctcctgtg tgctgctacc 23641 acatctatct tcctaaagag gagcccaaac acagaagtca ctgcttccct ggttacaaac 23701 cggcaatagc tccccgttgt cttttgtatt taattacgac ctcttagcct ggccataatt 23761 tcctttcaac tgaatctctc actgtctcag ccaagctgct cccaaacaaa ctcactgctc 23821 tcccgccttt tggttgctca agccgtctct tcctccacct gccaaaatcc gttcaaaaag 23881 ctcccacctc accccacctc ctgctatccc agggcttcct gactctctgc attaaagtga 23941 attctctttc ctgtgaacct ccagaacaat ttgcttgaac ttctcttgta gaacaaacct 24001 tattccagca tctatcagag acaataaggg tcttagaatc tagaaaacag ggtcctggga 24061 gggcacagtt cccacacgtc tatttcttcc aYaggacctg cacgctgcct tgctgttgga 24121 gatctgtgca gtaggcagtt gtggaattaa aagcaacacc ccatgtcgct gaatgttcag 24181 ggatcacagg ccactgccgt ttcccaccca ctcccagcct ccggggagtc ttagcctgtg 24241 gagtcccagg aagcacatgg aaaagagagc cttggaacca gagtggagtg acagctaagg 24301 ggtgctggag gcccctgtga ccttgaYcat gcacaatgcc cagaccagct ccgacttttt 24361 cctctccttc acatatttaa atggagtcga tattggggtc agcttcatgc acggagcctt 24421 cttcagcttt agaggtgatt ctgcagcctg cacaggagtg tgcacttgac acagtctatt 24481 tttagcctcc cagagaccgt gaccaacatc ccaagctgag agtgggcaca cctgctgcat 24541 tctaatgagg cagccccact cgcctttgcc agcccgcccg ggatctcacc gacgtgaaat 24601 ctgatgttgc taaactggga agtctgctta tttcccaagg gcggtagcct aggtacactg 24661 ggaagatggg accatcccac tgcccccagc tcactcccct gcagccctgg acacagaaca 24721 gtcttgggac tgcgcggagt gattccacgg aggggttgaa ataacttggc tttcttgatc 24781 ttgctgtgtc ctaggattcc cctgtttctc ttgctagaaa ggagacagta agtctgagct 24841 gacccagctc acagacaaga aaatcgagac atagaacaag gacatgatgt atgtaataat 24901 cataagcact tactatgtgc cagcctgttc taaagtcttt ccatatatca actcctccaa 24961 acttttggac aaatttttca ggtaggtttt attatgattt gtgttctata gaggaggaaa 25021 agctgaggca cagtgatgac aaattatttc ccaaggtcac acagccaaca agcgctgggt 25081 ttcagagtca ggcactgtgg ctccagggtt tgtactttca gccagttcgc tatctgcctc 25141 ctagtatcta tttttaattt tactagagcc aggataggac ccaggagcct ggattcccag 25201 ccctagagga ctgactacta gataatactc ctttttttat ttttctagtt cagccctgct 25261 ttgaggcctt tactgtgcct tgtacatctg ggtctcctgc actccaggca gaggaggtct 25321 cctggcataa ctgcttctgt tgcagtgttt gagcttctgg gctccaattg ctgtctctgg 25381 gctccagaag ctctgtggac ccccatctcc ttctccctgc tccgcctagc ctgtggagga 25441 ccagggagca gacagtgatg ggcagcagca gtgggtgtag agctgggctg ggcctcagga 25501 ttggggcacc cagaaatagc aataattggt tgtgtggagg ccatcagtgt gggtatccac 25561 agtgctgaat tcagggtaga actgtgaatc agaaactagg gggcaagaca acaggtagga 25621 gacaccagaa cctaagacat ctgcattttg ggggccgtat cctcttctag cttgatgctg 25681 cctgttgagt ggagagaagc ccatgggttc acgttcctga ggatgcaggt gggacttcgt 25741 ttcctctaac aaactcttac tatatgcctg gcccttttct aagcactttg aaatacaaac 25801 ttgtctaatc ctcaggacaa ctctaggagg cagggaccat tttattccca ttttagagaa 25861 aaggaaactg aggcactgag aagttcataa gtttgcccaa agttgtatag ctgggaaatg 25921 gcagagctgg gattcagctc cggaatctac actctcaggc accatgctgt gctatgcatc 25981 tttcccttta ttgaatgttt cctatttgcc ttcaaaggaa gatactattt tccccatttc 26041 acagatacag aaactgaggc ctgcattgct caggtcacct agctaataag agctgaaggt 26101 gggtgaaatc taggtgtgYg tggctcctcg gtggactgcc atctctggac agatcacagc 26161 catgagccca actgctggga gctggaaggg ctcacctacc tccctttcag gaagggctgc 26221 tgtggctgct tgaggccggg ctcagggagg gggaaggaaa gaggaccgca agcctccgag 26281 ggcgggaccc cgttgtctct cctaacaccc gacccccttc tcttcccctc aggtgaacag 26341 ccccccctcc cagccccccc agcccgtcgt ccctgctaag cccgtgcaat gcgtccatca 26401 tgtgtccact caacccagct gcccaggacg gggcaagatg tccaagctgc tgaacccaga 26461 ggagatgacc tcgagagatt attacttcga ctcctatgcc cactttggga tccacgaggt 26521 aaagtgtccc gagtgggtgg ctaatggggc gaggctgact ctgctgttct gttgttttca 26581 gaggcagcat agtgtgttca actccttacc atggtaaagg gagtgctccc agtgttcctg 26641 agtcctctga ccctttctcc aatccggggg gcccctctgg gagggggcca ggccaggcct 26701 ggagcagggg agcaggtgaa agtgtgtgtc tgtatactcc acagccagag agagcacaca 26761 aggtgcttac ggtccatttg ttttacattc cagctcccgt gtctctcccc agccataaac 26821 ccagctcatc cattgtgggc tggatagcgc tggtctttgg accaggagct caaatgctgc 26881 agtcagagtc ctgaggcagc aaggaccttt cagaggtcat gatgtgcatt cttttgacca 26941 atgagcacct ccgggggaag agctgcagga agctttcttg ggagcttggc ccaggtctga 27001 caccctgatt gattgtctgg aaattcttat gtctaaatgc cagtttaccc catagcaggg 27061 aagactaatg ttgactatgg aacagaacag aacctcctaa caagaggcat cctggccata 27121 gtgggggcct aatggtgccc ctactgtata tctttcatta taatctccag cactctctcc 27181 agccacccca aataaacaag taggatttac tgagtgcttg ctaagtgaca ggcacagttc 27241 taagcacatt atacgtatca tttcatttaa actctatgaa gaaaatatgt ccgtgatcct 27301 cttacagcat aagaaaaaat tgaaaaagga acaaaagttt gcttgctgtg caaatcggtt 27361 ttcaaaacaa gtcttgaaga tcttccttcc acgtactcac tgctgtaaac tcttcctatg 27421 tggaaatgat gaccctgcca ttgccggaag ggtgtttagt aataatagcc agctcttttg 27481 tttgtttgtt tcgttttagt gcttactacg tgctggtgtt gttccaagca ttttatatta 27541 ttggttcatt tattcttcag gtcaatcctg caaggttggt gttattgctt gtccccattc 27601 tccagatgat ttaggccctt aagaatcaaa tcaaccctca ttcatccttg acggtttttt 27.661 tgtgtgcgtg tgtgcgtgtg tgaaaggcca caagctagta gatggcacag ctagcaatca 27721 aaccttcacc ttttgttcct aaccatcatg ccatacagcc cttaaaacaa gtttcctttc 27781 tttccatctg gaaactgtaa aaattaaatt gccatatttg ttcctgctgg ttcttctgca 27841 gccctacatg gaggtagagg gtggaaggag gccccccagt tacttctaga ctcaggggct 27901 cagcctcatt taatccaggg aggctcaagg tttgggtccc tgagaactgt tcaccatgta 27961 aaaccattaa gcctggacct gcaggggagg aggactgggg cctgtgttcg. gtccagaagg 28021 tcctggccca ggagggcctg gacagctgag cctgcagctt ctgggagata aaatgccatc 28081 tcagggcaga tggatgaact cttacccctt ccttgaccct gctctccact gggctaggga 28141 ttcctggagc cccatccttg gcctgtgaga ggctcttggg ggcaaaagag actctgcgaa 28201 ggccccttcc tcaagacctt gtccctaatt aaaagtcatg ttctccatgt gacaagttct 28261 aacaggcctg tggctctggg tacccatttc aggacagatt cttgggaaaa gagagcagtt 28321 ccagggaccc caaaatgtct cctcttgggc ctgcccagaa ctcccccatt agaaaccaaa 28381 caaccatgag gtgcacctca agctgggtct gcagtctccc ctccccactc ggagcctccg 28441 tgatcggctt cttggacacc tccctctgag ttgctaggtt cctgctgagc cacacctttg 28501 gcgtttagag tgtgctccac taggctatta ccgatctcta taattccttt gggacttggt 28561 gtccccagcc tgttacctac agcttggcac attgtctgga gagcaaaggc ttgttgacat 28621 ggctgctaat ccagtcattc aggcgatgcc tggtcagcac catgacccag cacccagggg 28681 agaggacatc aagtttcacc aaataaatac tagaccagtt tccctcaatt gtgtgtactt 28741 atggaaaagt caagcttgtg catacgtata tataaacata gtgcgggctg agcaggggac 28801 ttagagtata agacctgtga gtcatagatc acattcctgt cctgggagag tgcttagcag 28861 ccttcccatt gggaaatact tctggacatc tagcttaaat ccctcctgct gctgctatag 28921 accatctcat aggtccttta atgcaggaac agctaggtaa ccttccttcc ccccgaggtc 28981 tccttttacc ctgttttcag tttcccagat catctgcatg aaaggaggtg gggggcacgt 29041 ggaagaactt ttaacaccat tcttcgcaga gagaaggcct acccagttct tgttatcaag 29101 caccagggat ctctgttcca tgccagatgg atcgtggtga tgcccttgcc tccttggtct 29161 gggcaagacc catatttctg catccaYctg gagccaYgct • ggccatttgg cagtcttctc 29221 cccatcatta acaagaccct cacacggtgg ggagcagccc caccggcctg ctgattaata 29281 gccatcagtg agtgttgagg aaacgtggtg cggataSaYt gggtttgatt gatctgtaaa 29341 tacaaacaag aaatgctgag tacaggggac tattggggct ggagagcaca gcagggggtg 29401 actctggaca cttctgttct catcccatgc tccattcaga gacaactcta tccccagcct 29461 ccagagggca ggggctagcg agaggaagac cctagccttc caatttaggc ctctctggga 29521 aacatggaat cttgaacagg agctgaagtg gaagatgtgt gcttcctgag gccgccacct 29581 Rgagaggagg tggtaggctc catgacctcc cagaccccag ctctgaaatc tcagcgtctc 29641 taacagtcgg cactgggctt ggtgcctcag ccacgagaag aatctttgcc aatgcggctg 29701 tccctccagc accctgagct ctgggtgcca atcccactcc cggccagctc ccttcctttg 29761 acactctcgc tgcaggttct gttgaaacag actctttggg gccttatagt ccaacaattt 2g821 gtcaatgggc agtcatatat ttaataggca ggaaagccag gacacaagtg aatccacagc 29881 tagaggctgg gaactgtttt ccacagggtg gcatgttcct tcctgaaatg tcttgggagt 29g41 tctttgggct cttctcccag gaaggggata gaggacctct tcttttggca agtcaggtag 30001 gggaagcctt gctaagtcac aacttctgtt ctcccagaac ttgtaccttc caacctaact 30061 cctggggcct gggacctcca ggaaaggaga cttggccaaa aaagcgacaa aggcaatgaa 30121 ctaaagggtg accactgggg ggtctcccca ttagcaaaca tactctctgt taggttttga 30181 agggaaggca agggttaaag aaagacacgc ccacagaaag agtgcagctc gacagcaaat 30241 acaggcttca tgtccagcat aaaacctaca gaagtggggg accgcctaat gccagagccc 30301 cctgctactt acaggctggg ggtacttata ggtatgggcg ggaggggtct gggcagtgtg 30361 gctcgctgcc tggcaggata ttaagatgtt cccgtgatga ggcggttctg gcccttgttc 30421 cggcaggatg tcgtcatggt gttccttgga cttttgtccc cagcaagata ccatacggat 30481 gtttctttag ttgggccttt gtttgccttg cggtcaagtg gttaggcagg atgtctctca 30541 tggcctgaac ccccgtgaaa tgcttcactt tgaccaaggt ctgcacaata gctgggagct 30601 tacaaaatgg tgcagtttgg acgaacaggc tctccggggg tactcagcca atccacttcc 30661 atctactaaa ggcacttcag acttttaact gtggttatga ttgaaacatt tctgcagcct 30721 ttgtcgttat tttgcctcca ttccctgctc atctcagcta tttccttgca tggatgaagg 30781 aaagggttgt agttatcact aagagccaga actagcattt tcgtgaaact tactacattt 30841 gtgtaatcat cataacaaac cctaggaagt aggtgatgtt attaccagtt tccagatgag

3ogoι ggaactgagg cacagacagc tgaaagctgg tctgggtcag agagctcaca aacagtggag

30961 gtatgatctg aatgcgggaa tttgggattt gaatgctcta gagtctgtgt aYttaaccac 31021 tgtgctgtat ggttttccgg cttactgagc acctgctatg cgccatgccc catgcctggt 31081 tctagatata ccatctgtct tgttgtcttt ggtccgagat ctcctaaagc gaaaggcttc 31141 agctcacctt caaagtattt aaagccagaa ttgaactgaa tccaaccaaa cccccacctt 31201 attcaacttc taataagatc aaagatatca gccctggggc agcacaggaa gtgatggctg 31261 ggcttcagaa tggttcttgc ctccttttca ccttctgtat ctcacctgaa tctcctctgt 31321 gactcaccct aactggaaac ataacagaaa gagaagttgg gaaatgtagc accacctggc 31381 tgaggtgaca cgttacaaag cctcccaacg tggtacccag aactccagaa aacatggagc 31441 caaacctaca gaactaaagg aagaaaaagg gaaatctcca gtcatagtta aatattttta 31501 acacttctgt cttggtaagt gatcacacaa atgcacaaaa aaaatcggta agaatgtaga 31561 aaatttgaat aatacaatca aacaacatga gctaattgac atttttagaa catttcatcc 31621 ccaaactaca gaagacatgt tattttcaag tgcacgtggg aacattcact aagatagatc 31681 ctctgctggg tcacaaaaca aagattaaag tcatgcagag tatgtttttt gatcacaatg 31741 aattgaatta gaaactgaga acaataaact atccagaaaa tctccaaata attggaaagt 31801 aggcagcact ctgctaaata gcccatgggt cacagaagaa gtcacagaag gaaagagaga 31861 ctatcccaaa ctaaatgata gtgaaaatac aacatattaa aatttggaga cggaaattca 31921 agcaatattt agagggaaat ttacagcttc aaatgcttat ggggaaaaaa agtcataaaa 31981 tcaatgacca aaacttctac cttatgaagc tagagaaaga acaaataaaa ctcaagtaag 32041 ttgaagaaag gaaataatta agatgaaagc agaagtcaat gaaatagaaa ccaagcagtg 32101 gagaaaacca acaaagccaa aagttgcctt ttgaaaaggc taattaaatt gataatatct 32161 agttagatta atcaagaaaa aaagagaaaa cacaaattaa aataacataa atggaggcaa 32221 ggacctcctg acgatcacac agatactcaa caggcaatgg gagaatatta tgacaatgtc 32281 gtgctgataa atttgacatt ttacataaaa tggatacatg ccttgaaaaa ataccttgtc 32341 aaaactgaca taaaatgcat tgaaagctaa aataaccctt tcctaattag agaaattgaa 32401 ttcatatgaa acttcctata agagaactcc aggcatatat ggttttactg gtgaattata 32461 ataaacattt aaagaagaac tatacctaac acaaactttt gcagaaaata tatgagcaga 32521 gaacacttcc taacttatgt aatgagccca gtataacttt gattaccgaa gaaaaggtaa 32581 gacaaagtta cagatcaatg tttctcataa ttatgaatat gcaacaaaat attagcaaaa 32641 aacacccagc aatattttaa aagggtaata catcatgaca aagtgttcat ttaacattaa 32701 aaaccaatct gtgaagttca ccccattaac aaaataaagg agaaaagtca tataccatct 32761 caataaatga aaaagcatgt gacaaaatta aataccaatt catgataaaa tctctcacca 32821 agttaaaaat ggaagggaac ttcttcagcc tgataaaaga catttataga aagcctaaat 32881 tatacttaat ggatatatta ttggaacaaa ggaaggatgt ctgtcctctg taattctatt 32941 caacatttta ctggcagtct ttgccagggc aataaagcaa gaggaaagaa ccaaaaaata 33001 aaaggcatac agataggaaa aaagaagtaa aattgtcttt attcacaagc gacaggattt 33061 ttcacacaga aaaataaaga aatctaaaaa aaaaacccta ctggaattaa tatgtgaaga 33121 gagaaaggct gcaaaataca aggtcatgta tacaccaacc cattgcaaaa tgaaaaattt 33181 taaacaccat atacagtatc acaaaataaa atagttgaat ggggccaggc atggtggctc 33241 acatctgtaa ccgcagcacc ttgggaggcc aaggtgggca gattacttga gccccggcat 33301 tcaagaccat cctgggcaac atggtagaac accatctcta cccccaaaat acaaaaatta 33361 gccagtctca taacccagcc tcaaaataaa taaaaagata aatttttttg aaaaactaaa 33421 taaaatagtt gaatggaaat gtaagacctt tatataaaaa tctatacaac attccagaga 33481 taaatgaaag atctacataa atggagagct gcaaagtgtt cttggattat aaaactcaaa 33541 attgctaaaa tgtcagttct ccccaaattg atctatagat ttaatacaag tctgatagat 33601 gccaggagcc tattctgtat gaattaataa gttgattcta aaatttatat agaaatgcaa 33661 agggcctaga aaaatcaaaa taatcttgtt aaagaagtac gttggcagac tctcactacg 33721 ttatttcaaa gttaatataa aggtgcagca gtcaagtcag tgttgacttt gtttatcagt 33781 ggaatagatc agagaggcca cacatgtaga gtcaattgat ttttggtaaa ggtgacaagg 33841 tgattaatgg aggaaatgtt tcttggacca tttatttgca agaaaaaatg agctcacacc 33901 cctaacttac actatacaca aaaattaatt tgacatgtaa aagccacagc cataaagact 33961 ctggtaaaaa acaaaggaga gtgtctttgt gacttggggc agacaaagat cagacagggc 34021 acaaaaagca cctatcataa gtgaaaaaaa tggaaaaact ggtctttatc aaaattaaaa 34081 actgctttaa aaaaagaaaa aagaaaatga aaaggcaaat cacagattgg gagaagacat 34141 tcacaatata tatgcagtat atctgatgaa ggactagctt ccagaatgta taaactgcaa 34201 ttcagtaaga acaagacaaa cagttcaaga caaaaatgaa cagaggactt gaataggcac 34261 ttcacaaaag atgatacatg tgaatagcca ataagcacat gaaaaaaaag atctacttca 34321 gtaaccatca gggaaataca attaaaactg caatgaggca tcaaatcagt ttacatccac 34381 taggatggct aaattaaaag atcagtaatg ctaaggtgtc tggctgtgaa gcaccttgaa 34441 ctctcacatt gctggttgga gtgtaaaatg gtacaactag tctggaaaac tctttggcaa 34501 tttcttatga agttgaacat gtacctaccc taagacccag gaaacttact tctaggtatc 34561 tacccaaggg aaatgaaaac atatcctttg ctattatgaa taaatagcaa aaaactggaa 34621 agaatcctaa tatcccacaa acaagtgaat ggataaatac attgtggtat agtcatagaa 34681 gggaatacca tacaacaaca acaacaaaag aacaaacctc ggatctgtgt aataacatac 34741 atgaatctca aaaactttat gttgcacaat ttatataaag ttctaaaata ggcagaagga 34801 agctttggtg atagaaatca gatcatttgt catcttggga gaggctgaag attgactaca 34861 aaagggcatg aaggactttc tggggtgata gaaatgttct agattttggt tatggtggtg 34921 cttacacagg tatacatttg tcaaagccct tttactgaac cagaagctta aaacctgggc 34981 tttttgttgc atgcaaatta taccttaata gtgttgattt ctaaaaaaaa attcacccca 35041 atacttttga tgatgaatta ggtaaaagcg tttgctaata ccttgaatgg ccaaagatcc 35101 ctacctcact accatacaca gaattaacat gttctccttg ggtcagagtc cactgtaaca 35161 agtaatcttg tttctctctc actgcaaagc caatatgctg gacagagaaa cacattttct 35221 agtctttttt tttttttaaa aaaaaggcaa acaaaacaaa atatacactc acaaaaacct 35281 ctttgaatga cgtgttcaat gacaattctc tcaccatgac agaaagttct gcttcgtgtt 35341 taacttaaat ctcttatgct atgttgtact gatctttcct ttggtccttt agtaaatcag 35401 agctttccca ggtctgaaca tgagtttctc ttctgatggt gaatagctat ctttctgagt 35461 agagttttaa ggcaggggaa gtttggaatg atgctgttag cacatggccc agctacccca 35521 gttttgtcct ctgtggctct gcctgatgat attatcgggt ctcctgaagg gtcacctggg 35581 gtggtccagg ggctcatagc catggtgtac acccaggtgt cttgaattca ctgacatttc 35641 ctttcttttc cctccatcac aggaaatgct gaaggatgag gtgcggactc tcacttaccg 35701 gaactccatg taccacaaca agcacgtgtt caaggacaaa gtggtactgg atgtggggag 35761 tggtactggg atcctttcca tgttcgctgc caaggcaggg gccaagaagg tgtttggggt 35821 gagcacgccg cttcctcctg catgctggct tccacagagc cagcctcttg ccctctgcct 35881 ccaccYgccc ttctagaagt acaaaatttg gtccatctct tttgctgggg tcacaccttc 35941 gaggagtaga agaaatcagg tgtgactctc aggaagggga gcaggctgcc tgtcccctgt 36001 gcatggctcc tggatcctta caaccactga catttgcgga ggaactgtgg ctttcctgag 36061 accattccaa tgtcatcatg acctttcagt gcttagcccc aaggtcagct tcagaggcag 36121 tgcaggtggt tactcggggg agctctggtt tgaatctctg catttccatt cactaggcat 36181 gtgaccttgg actattcact tccctgcacc tcactttttc tccatctata aaatgagctt 36241 aatagcagtc ccttgcccat agggtgattg tgaggattaa atgagtataa tacatatgta 36301 aagtgcttaa aacagtgccc agcatatggc aaatgctcgg cgtctattat tatagttgag 36361 atggggccct agagataatg ggaacatctc cttcttgttt tctttagagg gcaagtcggt 36421 caacttaaat tctgttgctt tggctgtggc agcgtttcca ggctagatgt ggaggctgac 36481 cctctgggaa gcctcctacc tatcccctgg ctctcccaag gcagctttgc ccagcctgat 36541 gacagagggc ctgggaaggt ccagagctgg aaagaaacta aaaagaagag ctgcgagatg 36601 ctggctgata tttgaaaaat gcagtgggcc cagggctgga gcacaagcat tcatcttggt 36661 caaaatgaaa ggcaaaccac aatgagattc ccagtctgca tgtgagccgg cccatttgca 36721 gaggcctcag cgacctgagc agcattcagt gggtctttgc tcccatgcat ttggttgggc 36781 catcccatag ccagccctgg ggaccccccc ccgcccactg actcccaggt tgactagatc 36841 cccctagatc ctcctggcca cctgctgcct ccagaggtct gctcctaagt cacccagcag 36901 ggcagcattc ctcctccaag cctgacttgg aaaacccttg ggccatggct gccRagggtc 36961 ttctggaagc ttgggctgcc ctcaagctgc ctcaggtgca gctttgacca ggaaaagctg 37021 tgacgttctc agccgaggca cttgctgagg gcaggggccc atccggaggc ccaagggcag 37081 gtcatgtcat catcactggt ataactgctg gttctccagg atggagacct caggcaaggg 37141 tcttagtgag gtcacagggc atcagagctg gacttgagtc ctctggtgac ccccacgtgc 37201 tttctttccc agcaccgagg ccccgtctca gtgccggcct tggtggggga cagggctgag 37261 catggtgtcc ctggcgcctg agtcatccgg gggctccagc caaggagctg tcaggaggag 37321 gctcccactt ggcgccttcc agctgcggtg acttggcgcg atctgtctgc ctcccgccct 37381 tttctctaac agctctttta taaatggctc caccacattt agctgggctc ctttccggat 37441 ggctcatttc acagtttctc ctgttccaga cccccttcca cccactgctg tcctccagtg 37501 gggagacgag atggcgggag agagagacag agagagaggR agggaggaag accatcgtcc 37561 cagagtggag acaggcacag agaaagagac agatgtgaca agagcaatgg agaggagaca 37621 gagacagaga aaggtgcaga gaaaagctag agaaatggga gaggggcctg gaaaagcaga 37681 aagaagacaa agtagaaagc acaaaagaaa agaatcggca gaggctggtg gatcacctga 37741 ggtcaggagt tcaagaccag cctggccaac atggcgaaac cctgtctcta ctaaaaatac

37801 aaaaattagc cgggcatggt ggcgggtgcc tgtaattcca gctacttgga gactgaggct

37861 ggagaatcgc ttgaacccgg gaggcggagg ttgcagtgag tccagatcgc gccattgcac

37921 tccagcctgg gcgacaaagt gagattttgt ctcaaaaaat aagaatcaga aaagtgaaga

37981 caggtggtaa agagagaaga gggaagaaat ggaagaggag aagatggaag aaaggaaaat 38041 gaggagggaa ggacaccgcc ccgcactctg agtgttgagc aagcttcggc tgagtttacc 38101 ctcacacact cacgtgcatY gggggcttcg acttctctcg ggaggacact gaggcgcagt 38161 taggaagggc agtggccagg cataaatcca ggcctggctc cgggtcgcat gctcctcatc 38221 actcaacatg gtcgcctctt gcagatcaga tgatgacatg gccagagggg gagaagaaga 38281 ggagggaatc acaccccaca gacagtgcag cctgaaggcc agggacctgg cagcccagga 38341 aagggctggt tctcctggga cctgcaccct ggctggagtc ggcctccttg gatgcagctc 38401 taaccaagtg accccttctg accccgtagg tgccctcacc cttcctcaag gcgtggccag 38461 aggcgtcaga aactccctca gtgccccttt gcgagtactt ctcaagggaa tggtccctgc 38521 cYgaggcctg ggggtagtct gaggggcccc caagtgtgga ggtgagtaga gcccagggcc 38581 ttagcacagg ccagcctctg taagagagcc ggctccggag gtgaggacgg ctcttggcag

38641 ctgcccctcc atgtccagaa cccctggcag tgtgcctgag acgctaaccc tgggctggag 38701 cttggcttcc aaccattccc atgagggcct gctctcaggg aaggtccact catctctcaa 38761 ataccttggc cctttgctta ggaggtctgg agagcctgga aagacgtctg aattaaaagg 38821 aataatttct ttcaaagatg aagcggcgag agctaacgtg gggggtggga ggggaagaga 38881 aagatcttaa accagccctg aggtcttgac ctggcttttt ccagatggtc ccatcctggc 38941 acgcggctcg tttaccctgg aagggctggg ctgcggtggg gaggatcatg tcgagggagg 3 001 ctcgcaactc tggcttggat ctgccttccc gcgtccccca cSgtggggag gacgtactgc 3g061 ctcctgccat tctctgctgg ccaggagcat gaggtctgcc agcccctttt gagtctccag 39121 cacagagatc aatccctcca tcacgggtgg tgactagaca tcagtctttt Sgcaaaggca 39181 gcccaatttc gtggaaggcc gctggccttg aggtgggggg gctgggtttc ggttttcagt 39241 ctgccacaaa gttgtgatgc agccgtgggc aagtcaccac ccctgtctgg gcctcagcgt 3g301 ctctatccat tgaatcggtg tgggtcttgc tgtgattttt tttgacgcct tgctcctttg 3g361 tcctatgccc tttccagatc gaatgctcca gtatttctga ctactcagag aagatcatta 39421 aggccaacca cttggacaac agtaagacat acctctgagt gttttctcct ggatggaggg 39481 gacgggaagc tcacactttc ttgttgggat ggcatagcgg gaggaScgca gagcacttgg 39541 acttggggag gtggtgcacc cagctgaggc ccccgccagc aagactgcgg ccatgggtac 39601 tgatgttccc cccgacacca ggccagctga ggatcacagc caccccctct ccgcttttgg 39661 caagccctgc ttgtagctaa atcccgagtt gccagaccct ttgcttgtcc ccagctgtgg 39721 gcaacctatt gccttctgca aaatggccac attcctcctc ctcctcctct tcctcctctt 39781 ccctccctct ccatgagccc cgacccaatg tttccccacc acctgcccag gggcatcatg 39841 gcagacccca ggctgtggtc ctccactgcc cacgagccct gtcactgctg ggctgttttg 39901 ggaatgaggc tgcttttggg agtgggccct tcttcagctg gagtctgatt atagagaggg 39961 gcgtcccttc ccttcctccc ctctcacctt tcccatggac agcgacattt cccagtccct 40021 cctctctgga gcccatcttg gaaacagacc cgcaagggtc cctgatcagg agacgtcctt 40081 ggagcttgca tctgacagca ggattagatg cagtcccgag ccctgtgctc agtgctgggg 40141 agaacatcag aaaggcagac agggcactag ccccctgtag gcatcctgtc ctactgcgcc 40201 ggggctgcag tgaggccgag agaggaactg gtagacagga agttgcaata cagacaggga 40261 ggtgagccac agtgagacag aggccgcctg cagcagaggg ctgcaaaggg tcagctccaa 40321 aaggcagagc tcactgcaga gttccaaaag gtgggaaggc tggagctggg agggaaggac 40381 gttcccttga ggggtctggg gcagggggaa aaagaggcca ggttgggaag gaatctgatt 40441 tcagtgtccc tcctgaggga gcctgggcag ggagttctgg caggtgggct ttgtcaagtc 40501 cgaggcaccg aggagtcagc tcagcctccc ctctctgtgc tgtgcgaccc tttgctctat 40561 ggatgcagcc cttgccatgc tccctgctga cctgccagaa ttcctctgcc ctcctagagg 40621 gtgcctgctg ccctgtcacc cctctgggtc tgacctgagt ccccaggccc aggtggtacc 40681 tgcctgcaca caacactaca aacctgtgtc catgtggctt cagccctgcc acctgtcctc 40741 tctggtgctt gacctacttg ctgcagactc tttgcaaggg caggagcatt actgactcaa 40801 caaacttctc tgcaaaccac catgagccag gctctgggga cagagcaggg aacaagacag 40861 gtaaagtccc tgacctcatg gaatccacat tccatttagg ggtaggggtt acagataata 40921 aataaagaag cagacactca aagaaaaata tcaggtggtg ataagtgctt tgcagatcac 40981 aaagtcagct gacaggacgg agagagaccc catggctgcg ttaggttagc tgctctctga 41041 gcaggtcaca gtgaagctca aatttgaatg acagaaagga gccaggctga caaaggtgag 41101 gggaagagca tctcagacag aagttacagc cagtacaaag gcctctggga tggactgagc 41161 ttggcatgcc cagaaacaca aagaagatca tgccgtgtgg ccagggcatg gaaagcacag 41221 ggatcagaga gggaggaggg gaccagatca cacaggattt gtaaccagga aaacaaggtt 41281 agattttatt ctccaggtgc tgcagtctgt tggaggattt caagcaaggg aggtggcttc 41341 tctatggagg atgggttgga ataagtcgca agcaagaagg gtgtgagcag acacacggga 41401 agaagctatt gcagtgctcc agtgagaggg gctgcagcag gaactgaggc agcagtggag 41461 ctggagagaa gtaatccctg tgggacatgc ttggagatgg aggcacagga cctgagggtg 41521 cattgagtgt ggggatgaga aaaaagagag aagcaaggat tctttttgac ttgggcaact 41581 gggtggatgg gacctgagga tgcattgagt gtggggatga gaaaaaagag agaagcaagg 41641 attctttttg acttgggaaa ctgggtggat gggacctgag gatgcattga gtgtggggat 41701 gagaaaaaag agagaagcaa ggattctttt tgacttgggc aactgggtgg atggtggttg

41761 gctggaggtg aagtactcat gggggtggca ggagtgagaa ggaaatcaag agctcctttt

41821 tgcatgtgtt aggtttgaga tgcccatcag acatccaggt aggtgcgctg agtcagactt

41881 ggatacgtgc gtccagaatt tcaggaagag ccagaccagg agacttccac ttgggagtca

41941 tcaacctata ggtggtattt aaagccagag gatgaggtca cttagggatg gtgtgtagct

42001 agaagaaaga aatgggccaa agatggggct ctagggcact acactgcaac attcggaggt

42061 caagcagggg agaagggcag caaagaggta gagaagatgc agtcggttga agggcattca

42121 ggagagagga ggaccatgaa gcccagggag gggggcttgc tcaactgtag ggaatgtgga

42181 gggatctggt ccggtaagaa cagagaagtg accaccattg actttggcca catggaggtt

42241 accagcgctc ttaacaagca caggctcaat gtggggctgg gagagaaatc cagttagaat

42301 aggttcagga aagactgtga ggcaaggacc agaaatgatg gaatagaaaa atggaacagt

42361 agctgtaaag gaaggtggca ttaagggaag aagttttttt aaaaaaaaaa taggagatat

42421 gaaaacgtgt atgtgattca ctggtgtagt agagggacag agaaagattg caggtgcagg

42481 aaaaagtaaa ttcagcagca aagaccttga gaaggtaagg tgtgtgtgtc aggggtggct

42541 tttgccctgc ccagtggagg ggtggtcttt gccttgcaca ggtggagggg tggtctttgc

42601 cttgcacagg tggtggggtg gtctttgcct tgcacaggtg gagaggcggc ctttgccttg

42661 gggcagggac agttcagcca tagaagtggg ggaaagtggg gagtgtgggt ccagatggag

42721 gtgccagtgg tgggaagccc ttgttttgct gctttcattt gcttagtgaa gaatgagaca

42781 gttgcatgcc aaaaagagag aaggtgaagg gaggtgagtc ctggaatgag agggaaggag

42841 ggagggcagc agataggctg ggggagtgag gattgctgcg atgtgtctga tgcctgtaga

42901 gatgtgtgac catagaggct cagtgagtcc catccttgct gttgtgtgat ctttctctta

42961 ccactctcag gagctcgagt gcgattggag tagaaggttg ccgggatcag ggctttgctg

43021 ggagcatgca gcagagggag ggggagctgg aagttgatga cagtgatggg ccgtgggatc

43081 taagctgggc caggaaggaa gcggagaagg atggtggtgg ttgtgacaaa ggctggggcg

43141 aggggcgggc agcatgtcta gtggccacaa gtggagctgc gatcctgagg cccaagtagg

43201 gggatgctgc tcagacccct tggcctctgg cttggtgtcc agcctttctt ggctcaccca

43261 gcggagctgg gtctcttctg tgccctcctc agagaagtgc ttgacccggg ctccctatct

43321 gcttactaaa gacagataaa gaaaactggt cgattctttc tctgggaggg tgacacagcc

43381 tggcctcctt ctccccaacc tgtgaaatag ggcagatggt tttccccatt aacaggtgtg

43441 gaaactgagg ctaggagagg tgggtgactg agccctttgc taaggtgtgt ttgtgtggat

43501 gcagaagcac caggagtgct gctgagcctg aaagcctgtt gggaggggag gcagtgtgtg

43561 ggcacagcag gatcagatgt cctctcagtg gtcctgagtc tcatccctga gccctgagag

43621 gcttccaaac agcacctaga ccattcccct ccctctgcac aggtttcacc tgtgccgtaa

43681 ttcctgacct ctgacccagc ccctgactct tcgtctccct ctcagtgcca gcccaccccc

43741 agtaaatgtc tggggctctg gaaacacagc ctccctggtc tccctcctcc ctaggcttgc

43801 aggggctact gccctgcagc cattcatagc agagtgtggg gtgggccggc aggggaggtg

43861 gctaacttcc cctgaggcat ctctgtcctg cttgccagga aaggaaccac acagccccct

43921 catcatcctg ctctgtctca caccataggg ctctcccctt cctccccttc ctccccttcc

43981 ttctcctccc ctttcccttc tttattttaa cctttgaaat actcaatata cagaaaaggt

44041 gcgcacacag ccgggttttt atggaatcct ttgagagtaa gtggttgatg caatgctccg

44101 tcatccctga atacattagt gtgcatttca aaccaacgag gacattttct acaagccaca

44161 tgcaaccatc aaagtcagga aattaaaacg tcatcattac ctaatgccca gatccttttc

44221 atgttttgtc aattgtctga gtaacatcat ttgtagcaaa aggatttcgt tcagaatgac

44281 acgttgcatt tagttgtcat gactggttcc cttcaagctg gcctgctcag actttccttg

44341 actttcatgg tcttgacaca ttggaagagc acaggccagt gttttgtagg atgtccccca

44401 gtttgggatt gtgcgctggt tcctcgtgat tggattcagg ttctgcatct tgggtagaaa

44461 tctcacagac aggatgctgt gttctcattg cgtacaattt cggcttgtct cattactgac

44521 agcatcactt aggccacttg gggaaggcag tgtctgctgc cagccttcgc catgggaaag

44581 ctgctctttt ccctttgtaa ttagtaagat tttctggggg aggtactttg agagcatgta

44641 aatatttcat tattcaccaa actaacattt atctgtctat ctatctacct atctatctat

44701 ctatctatct atctatctgt ctatctatcc tgtctatcta atctatctaa tctagctgtc

44761 tatctgtcca tccatccagc cagccagcca gccagacagc cagcgttcat ccatctactg

44821 atctgtccat tcatttcact atagattcct attttatgta ataggttaca gctgttatca

44881 ctacttgctt cgatactcaa attgtccctg atttggtcac tgatgccatt ccagctggct

44941 tctgtatccc tttgaaatgc cgttttccct tttcccgagc cttcttactt tccagcacaa

45001 gacattccag gcttgtcttg tgcctccatg cctctgttct ggaatcagtc atttctccct

45061 gattccaatt agtggaccac agcatttaga aactaaggtc ggggctagat gctcgttgat

45121 tttagaacgt tgatgctccc aggctgtttc actggggaga gctggggatt gtgtgtctct

45181 gagtgagtgg acacatttac acaaacttta ttactgtatc tatttatatg tattgtcaag

45241 taggagctca catgatactt cagtgttaac caataccatg gagtttcctc tcatttcctc

45301 cctttccata tttctacctc ctttctctac cagaaaaacc agactcttat tattggtaat

45361 atgtttgctt actactcact tataatatgt ttacataccc ctgaatgtaa ccaatctccc

45421 attgtcacca cctcctgccc caggcagatg tctgtcaccc catgctggga tctgacaccc

45481 ttgctgggca gcgtcccaca tgggcaccct cctctgcttg agccgggctg ctgtggtcca

45541 tgctgacccg ttgtggcatc cgcaccccta ccatttcctg ggtttgctca gccccacctc

45601 atggctttag catggaatcg tttatgctct gggttttgat ggctcagact tgattctatg 45661 ctaccgaggc aaaggcttga agagtgcaaa cctttgtccc caagggaata gctgccctcg

45721 tgcccattcc tcccttcaca cacctgttcc agggaggagg gacctccagg tccagggacc

45781 tccataaagc tgagtggtct ttactttttc ctcccagggt ttgcaacagg tgggtagagc

45841 cagcgaggcc acgcagggcc ctggctgctg cacctgctca ctcacttagc cttggtgtgt

45901 gtactcagag gaggacagct tggctgcacg gatgcttcca tggaaatgct tttgaaatgc

45961 tgcaacagcc agccatgtgg gtctcaggag cgtaggtgta gagacataaa taacaacacg

46021 gggcatagaa tacctgcttc ccagaagcaa tcagcctctc tccctctcca cctccgtaca

46081 gctcccgtga tggagttatt cacatgtaga cacacaccca caggaagcca cctgcggcag

46141 gcacgcagcc ttcacatggc ttcttccaca tgtgtggccc acacgcgcgc ttcagtgact

46201 cctctttgac ttaagcacta acaactatta tttcctcccc atctgatgag gaaaccagtg

46261 ggctgccgag atgcttaaaa aggtagattc atttgtgaag gttgacatag gagctcagag

46321 gttgattgca ttggtttaac tctagaaaca aaaaatgtat aacccgttta cttcccagaa

46381 aactcaagga aaaaagcatg cccctccttg tccttctcct acttttgcat gacctaaagc

46441 ataaatgtca tagctacaag aaactttaag gtagcatgac atgaggtagt ggcaagggac

46501 agctgggcct ctgcaactta atggtaggga ggactttgtc aaatctcttc ccccttctga

46561 gcctctattt gcccccttta gaggagatag gccagtgcaM agctcgtaag gttattaggg

46621 gctcagagac tgtggaggtc aagtgcctga tatagggcct cacatacagt aggtgctcaa

46681 atgtcagcta caggtcattt caggtgtaag gKtctgcacc ttgatgattc ttggccacac

46741 actcccagcc ttatataagt gctctgacag taatcctctg tgctttgcaa ccacccagtc

46801 ctgggatgat tctcctggtg gggattccac aagtgctaca catccccagt tccttcctct

46861 tttgcttagg agggcagtgg ttggaacatt ctcctctggc catgttttag cagctctttc

46921 accaacagag ggtcgtgcta agaattaaac acagccagtc aatgggaggg gcccagatgc

46981 tgcacttgtg gcaatgcacc tccagtttct gcctgccagc ggttgtggaa aacaccatgt

47041 cacactgttc ctagctggag accaaataca atctgttgtc tattcacata ctgctgccaa

47101 gcgatacctc ctaacctata tctggttggt ggatgttttg aatcaatcca aaccaagagt

47161 cacatgtttt tattcatatt caacaccaag ttgttagagt tggtcttcta tcacaaatga

47221 ctaagacgcc ctgcagatga tcactctcct ggggtcactg ctcccggttt gtgatgggtg

47281 tcctacggtg agggtggaag ctcctacagg ctgctctaca ttaggctctt aaccagctcc

47341 ttggaatagg gtcatgcagc caagtcatga atccacacag tactttgtca tcttctccct

47401 taggatgcca tggcRgtggg gccttgtaaa cgtccttgtt gaagtcccac atgatatact

47461 gcaagcatgg gctctggaat cagactttct ggctcacacc cagctctgcc agaattaggc

47521 tgtgctcttg gatgacttag tttatgtgcc ttagtttcct catctatgag acaggaatta

47581 gtggtcatac attccagggc cattgtgggg atcgcatagt tgctgtttgt ataactgtgg

47641 cactctggag tcagcacctt acaggatcct gagagctgac tgtgaaagtt tcagtaaatt

47701 tgcagaatgg atgccatcat tggccatggt ggaagtatct ataccacaga attcagcaaa

47761 ggcgacaaac cagggcttct atctcctgga gagccggttg ttaagtatct ccagcacacc

47821 actgtataaa acacaacagc atccggtggg cactaagcaa ccaataaaca ttagcggttg

47881 ttatgattat tccgtttatt aacttgacta ataaccatat caaaaaaaga aatgagacca

47941 atcatatgta attattttta atgagcctgt agtagtgact gctggcaact gctacttcct

48001 tccctaacag ctcgagaaac aacccattaa taatcttcaa agtgagtttc atgtattcat

48061 cctttcgagt attattgagc cacgtactag gtcctgtgtc gggcataggg gagttcgtgg

48121 tgtgactagc acagacaaca tctttgctct cataaagctt acagtctcgg gggaagacag

48181 acatgaaggc aagcgaacaa acaaaatcac aacatcatca caaactgtga acgtgcttag

48241 aaaaaaacag catggaataa ttgagaaaat ggggatgtgt tttttccaat tgggtggttg

48301 caggggcatg ctggctgtca cacactgcct gccaagagcc aattgcgtgc gctcatctct

48361 tctcaactct gccttgaatg acatcatctg tgtcgttagc ttgaaattgg ctatggtgga

48421 agtatttaca ccacggacat tggcggatgc tacaaaccgg agctgttttg ttttcccttc

48481 tggagaccta aaggtgaaga tggggccatg ctgagagcag tgggaagagc gttttacctg

48541 cctgtataca ttccctcagg tgggagatac tttctgtccc atggaagctt ctgctgcagg

48601 gagagagtga aaccattcca gatagagaaa cttggaatgg ttttctgaat acctgagccc

48661 tggggaagct ttggttgccc tttacattcc cattgatttc aaccactcta cccagtacca

48721 gtgccttctt gataacccct gctccccttt ggccaagccc acatgatcat ctgcttgtgg

48781 ccatggtgct gggtatctgc caggctggac cacaggtggg gttctaagtg gtgggtgatg

48841 atctcgggtg ggaagagtcc tggtattgtt ctgattcact gagtactcca gccactgcct

48901 aagggaggag agaaaccagg cagggtctct ggccagggaa tggctctggc aaagctagca

48961 gggctttaga gctccagcca agcacgttgg gccctgagcc ctcaagagag ccagagcggg

49021 ctagaacatg aagccaagca gattacacag tgaggacaaa gcagaccctc gagtcctatg

49081 ttctcgggtg agtgggggat ttgggcaggg agaggggtac tatattgtgg aagcgaccac

49141 cctgaggctt catgacaccg ggggctccct tatgccactg cagcaatagg gtcagtttgc

49201 tgcaggacat agtcccagtc ccaccattca tggagggtag agatatcgac atcctttttc

49261 ccatcactcc tgaccagccg caggagaagg gtaggttagt cctttgcctt ctctgatttc

49321 ttttctctca acatcccaag cagttgctcc atgtccacaa gaatcccagg tggtagggag

49381 gtcagatata cacccatttg ccgggtgagg aaaggaacca cggagaggca caaacatgca

49441 caacaggcct aggttcagcc cccacaactt gacttctcta aactccagtt cactccttag

49501 gcaaaaataa taataaaacc aagcacacaa gttcctagga ggattactga agtaacatac

49561 ggaaaatcac tctgcaagct gctattcaaa tgctagtaat tttttactgt cacaattagg 49621 actagtttga atatcttttg tctcttaacc caatgccccc cacctttttt ccttcaacat 49681 tgctcattca tccatccatt cattgagtaa tgattctgaa tgtttgtgag gagtcaaatg 49741 ctccgctata tcctggaaat aggaagctaa aatagacaac gaagagaagg aatgcatacg 49801 ctggaggtga gccgggccct ccgcaggtgc aaggcagcca gcatgggtgt caccaaaata 49861 ggtgtatgag caaggaccaa gggagtgggg agggcgagcg aagggctttg ctgcagtggg 49921 gttggcaggg gggtcagggg gcttcatagg ctcataatat gttcccatgc ctgtgaccct 49981 catgcctcct cttgtgtggc acaggacctg ctctctgaaa gagtgaggac ctaaaaatga 50041 tcactaactt cagatcctaY Rggcatcagc tgaccctgat ggatgcactg gaggctcaaa 50101 tgaggttgag ctggcctgat ttgtttaaaa acaaaaatga ccattaatga gaatgactag 50161 atttctgtaa gaaccactca aaccaaaaag aaaaaattcc actcaaaacc atttttaaaa 50221 atctggatgt ctcacttaca aacttgaagc tacaggagaa gttttcccaa tttagagtct 50281 attgctccct gctgtgcatt tagttctgat taatcaYtct gtaatttacc agccagagtc 50341 ctgtcatagt tcgttgaaca aactttccat catccttctg gaataaaaac atggatccgg 50401 acggtgacct cagtgcaacc ttgagttgat gcagttttag tgacttgggg tccagattgg 50461 gcatggagct ctgcagccta cggctgctcg gaatcttaat atcaatagct tagaccccct 50521 tgaaaatcct ttgcatggag gagaagggaa gactgctgct gtgtgtgccc acacacttcc 50581 ttgagccagc ctaatgccct atgttggcca atagccccta gtaagttggc ataYgcccca 50641 ccatgacagg tagcattttg tagattggaa aattgaatct ggaagtttaa gtggttgctg 50701 gtggtgacta cagactgcag gaagaatatt catggtgatt cagctggaca gttgtatttg 50761 gctgcacaga aagaatgtga cctcttaaaa ataaaaaata aaaggaccca ggaagtgttg 50821 aaaatgacag tcaaactgga acttggaggc accatctttt tttattgatg ccagctgtct 50881 ccaccagtga atcttgcaga atgccttaca cataacaagt gctcagtaca catttgaaga 50941 accgcagctt tctggcactg caaagaattt cagattcaac ctcccttctt tttttttttc 51001 ctaatgagga aaataaaaga gaggagatgt ttgattgaga ttagctgtca cctggaacaa 51061 gagcgtaagt tgctgccttt taggattcca gcataaagtt gtgcaggttg agcacaaaag 51121 caccggagaa aggggataaa tggagtctaa aagccagtcc agcactggat tgaagggaga 51181 tgggtccttt tcctttgaca aagggctcat ctcctcacca agccaactgt gggRccatgt 51241 ccacactgag aaatgtctgc acttgaatag atgtagaagg gtgatgttaa gagaacagaa 51301 gtccagactg ttgaggattt tatagggtta actgattcct tctgcctttt tgcaagcaga 51361 gattgtgatt tttgctattc tgtgaccccc tRtatctagc tatcatctat ctgtcttcta 51421 tatcgtctgt ctatctatca atcatctctt gtaatccata ttgatgaggt tacagcaact 51481 aattgataag agggctaaca cagagaacat gagcagcagt aactctcttt gggggacacc 51541 tgaggaatat ttcatacata cctgtttgtt agacttgatg atggattact ccttgtctgt 51601 ttcctgcagc tcctaataga gtcctgtcca caaaaattgt catgggtgga gccttgtact 51661 aaacactcag ggtagaggtc atgaggcccc ggaggcagga gaaaacatct tctagggcta 51721 cagagaggtc atgatataaa tgcaggagga ggaactgacc catagccaca cagacacagg 51781 cagacattag ggaagaacct tcaagaaacg tgcaaagaaa aaaaagtaag ggaggccatt 51841 aaagacaatt tttaagttta caaaactaag gcaagccagg ctttgcatgc aaatgattag 51901 gcaggtgagt catgcatata tttgtcagtt ctctttcaaa ataagaaata aattaggcac 51961 aatgtttgca ttttaaaaaa tcctttactt tgccactcta tgaattttct tagtgcaccc 52021 tgggccctgc tctcagttga gttcctgccc tggggtctct gagacccaga gaaacttcaa 52081 cacctacccc tcccactccc accaaaactt ttggagaata gctcttcctg ctcatacttt 52141 ttaatggtag gggcttttga gcagtaacca gtcaggaggg ccacccaaga ctgaacctca 52201 ctgtagagtg accagggtca atgcatgtgt acaaagtgtc ttactccttg tagagcaggc 52261 tgtatccaat taaagcttga ttaaatacca catagtggag agtaaactgt tattagaagc 52321 tgctaatgga cactccatca cctgcattat tcactgtgaa gaaactaaat aaagccagca 52381 aacggtgtgc tctttgccat ccaggagcct cagtccaaat taattttcat gaaactcaga 52441 ttctaggcag atgtggttct tttgattttt actcctaagt acaggccatt gtttgttttt 52501 cccagcaaag ctcaggcatt gtgtgagttt ttttcagagg atattgcaga Wtgagagttt 52561 cagagcatga atatatgtaa cctttcaaag gaaatgttca gaaagaacaa accaaccaat 52621 acatcagcct gccaatttaa cagtggtatc taaactagct tgctcagatc tttacagcaa 52681 caaatacaaa aagggactcc aaaattatgt gtatgtctat gtcagtttat caaaaactca 52741 actaagaagt gtctcctccc acagaggaaa ctgaagttct tgaaggtgac tcataagaag 52801 aagccactgg ggacaggggc tttgaccctg gccctatctg cttcccctct ccatctgtgg 52861 atcaacaagc aggaatatgt cagataatgt ccaccttctg ttgagcttta gctatgggcc 52921 tggcactcca catgtgttat ttcatttgat caatacaatc accctctaaa ttgatattgc 52981 ttttcatggt tgttcacttg ggaattggag tttagttagg tcaagtaact tgtctaaagt 53041 cgtacagcta atggtgagaa gatctggcac ttaaacctag gtttccctga ctgcagagcc 53101 catgctctca tcaaaatatc aatttcctcc ctcacaaaca ctagaagggc acccatttgg 53161 tattgagcct ggctgtgaac aaatgcaaaa gcaatagagg aggcatctat gctttctttg 53221 agtttgaatt gtcatggtaa cctaacatag gggtgggggc cttgagaaga gttttagagt 53281 catgtcatat cagatctggg ctctgtttcc actgctgcta ctcaacctct ctaagcctcg 53341 gtttccttag ttgtaaacaa aaataacagt tgaccccgac taccacaggg gttaggggtg 53401 ccaatccccc acacagttga aaatccaagc ataatttttg actcccacaa aagtaagcta 53461 ctatcagcct actgttgacc agcagtcttg ctgataactt ggtcaattaa cacacattgg 53521 ctggctgtgg tggctcatgc ctgtaatccc agcactttgg gaggccgagg cgggtagatc 53581 acctgaggtc aggagtttga gaccactctg gccaacatgg tgaaaccccg tctctactaa

53641 aaatacaaaa ttagccgggc gtggtggcac atgcctgtaa tcccagctac ttggaggctg

53701 aggcaggaga atcgcttgaa cctgggaggc ggaggttgtg gtgagcagag atcacgccac

53761 tgcactccag cctgggcaac aagagtgaaa ctccgtctca aaaaaaaaaa aaaaattaac

53821 acatatctgg tatatgtatt atatactata ttcttaccat aaagtaatcc agagaaaagg

53881 aaattgttaa gaaaatccta aggaagagga aatatattta ccactcactg agtggagtgg

53941 atcagcatga aggtctctgt cctcattgcc ttcacatgga ataggctgag gaggagggag

54001 aggaagggct ggccttgctg tctcaggggt ggctggaaga ggtggaaggg gaggcaggca

54061 cacttggtgt aaataaaaaa aaaaaatctg cgtgttcgtg gacctgtgca gttcaaagcc

54121 aggttgttaa gggtcagttg taatgtgctt acctcacagg gctgttggaa ggatgacgtg

54181 ataccacgca tataacgggc ttagcgctat gccaggcaca tagtaatggc tcaatttatt

54241 ttacagggaa aacatgcagg tagttttcaa ttatgttggt ataaactagt ttggtaaagg

54301 gtgagctaca tcatatccta aaagtagaat cagaataggg ctgaaacctg gagatctggc

54361 cctgaagtga ggtgcttgtg gttcctgggt ggggtccctg caaagtatgg ccctggggtt

54421 cttattttcc agtcatcacc atatttaagg gtaaagtgga agaggtggag ctgcctgtgg

54481 agaaggtgga catcatcatc agcgagtgga tgggctactg tctgttctat gagtccatgc

54541 tcaacacggt gatctttgcc agggacaagt ggctggtaag tgtcctgcat gctgtccccg

54601 cgttggccgg ctggctgtcc tgctcctcta cccaaggcct gcagcctagg aggcatacga

54661 agacttcaga gaagactgag gccaggaggt cactgcccca agcccctctc tctagagcag

54721 atctgtatca gggaacagaa tggttgcccc gggtccagca tgtgtaacca tcagagtgga

54781 cttccgtggg tctcaccgca gcctcttttg caataacaga catccgttct ctcttgtcga

54841 gttaaaggtc cgtttcggtc agcaagtact taggacttgc atggctgcca gagccaggtg

54901 tgctattcat ctgggcttct ccaggccaaa gtcgtaacat ctctcactgc tcctcactgg

54961 atttaccttc acctcacctc atttgtccta ttgactccac ctaggtccct taaattttcc

55021 ttgctccaaa ataaaaattg agcactgctg tcctagccct caccccagac aaggtgacag

55081 tccactgcat gagagatggt ggcaaggggg tgcttgtctg gtgactctRt gtgcagttca

55141 aaatgtgatg tctttgtcag gtgaatagat tacgagaccc atttccccac aattcatcaa

55201 cagaaacctg gagggcttat gtttccagac cgggcagctt tgtacgtggt agcgattgaa

55261 gacagacagt acaaggactt caaaatccac tgtaagtccc ctcttRcttc tccggtggac

55321 ttccactgca caattggggt gggaggcact ccagtgggcc cgagatgagc aggcagtgac

55381 atgaacacca ttgctgtccc tgaagaggag cttatctggg accctttctg gagtctgctc

55441 tctaaatgtt tctatctagt cccaagggtg ttaggtctac agacagaaaa taagccatat

55501 ggctgggatg agagaaatgt cctggggtga aagaatgaat gcaatgtgaa ttaaaaattg

55561 gactgaggca gcagaagctg agtttttgca gagatcagca gggcaagtgg cttgaaacct

55621 gtcaaggttc agttagccca aaagtccacc gcaggggtct gaagtagcag gtctcttgcc

55681 aggccaattg ttttgaatcc tgcctccatt ccattcaaac ttatcaaaat aatattgatt

55741 ctcttatgca aatacatatt atttgaggtt cttttgagga atagatagca gagggggtgg

55801 gaaagagtgg agattttgct ttgaacaatc aaacgaaagg cgagtgtgca tgtgtgcatg

55861 aggcaggggc tcgtatctaa acatgtattc ttaatgcctt atcagctagg cgtgtgtggt

55921 tctctgagaa caataaagcc aaaaaacttc tcctcccccg caatgtttta cctggtctga

55981 aaagggctgt tatcctattt ctcgtaaagg gtgacacttc tctgtgacac aggcctgatc

56041 cttaatgaga ttataccaaa catgtttttg taaagttgaa catggctgtg tctcctcaac

56101 cagaaccaaa tacaacaaag gagcaaagaa cccctcaaac aggcaaacac ccaaaaatcc

56161 aaattaaagc aagaggcaga agctccaacc tatccatcag actgggcaca tctgcggttc

56221 ctgccccaac agggtggtcc attcctactt ggcaagatta ctgtggaggg gttcacagat

56281 tgaRtagaag aataaatgcc tccaagaggc taagactcca tccacagttc aacaaattgW

56341 ggctctgtgg atttaaacaa ttgccatcta atcgtcgtta gtggcactga tgaaaactcg

56401 gctggactct gctatggatR tgtgtatttg tgtgggttca tgcctttctg gaaatataaa

56461 ctcaaagtgt gaagttcaga gccaggttca gaagaagaca aaagtgggac agctgtttga

56521 agctctgtgc cctggaaacc gtctctggtt gctgtctgcc tccagccaat ctggtgtgat

56581 ttccactatt tgacctcctg ggggaaggag gcaaaatacc aaatgaggac agtgagaggc

56641 aggggggccc aggttaaatg ctttgcacac tgccagccct gggtttaaat cttggctttg

56701 ccatgtccta actgggtaac cttgagcaaa ttatctaata cctttgggcc tcagttaaRg

56761 gataattttc tcaatcccac agacttgtca tgaggattaa gtgagatgac atatattaaa

56821 ggacgtgaca gttcttggtc ctataatggg actagatggg aactagtttc tgactgtgta

56881 gctaagcccc tttctgcccc tggctctggc aagtgagcct gactgccaag cccctggtgg

56941 ctcagaatct aggacagatg tactctcatg gaagattgca gacacaactc cacagtgagt

57001 gttgatcaaa tgcatgtata aataggacat attttgccct ggagctgcat tttggagttc

57061 ttgctgtgca attgtactga atagtgtttt gaggaggaaa gcttctaggt acattcttca

57121 ttgtcaagtt cacttagata tttattgagc tccaacccga ggcacacctc tttaagaaac

57181 tttctcatgg tttccacaac aaagatacct gtgtcaggag cctttgcagg tatgcacatt

57241 gcaatgagcc agcctggggc agggaggggc tcctaaggca ctggccccag actggagatc

57301 atgtgatttc tttgattctc attgcagtgt tcataccttt tggaaaagga aaaaaaaaaa

57361 tctgaaagtt agcaccatgt tatcttgtgc ttgttctaga gtctctgaaa aataccccaa

57421 cctcctcccc accccaaaag aacaccaaga aacagacact taaaatgtat ttaaaataca

57481 ttttctattt acatttttga aaataatcta tttttttgta aaggaagcaa acccacttag 57541 aaattcattt caaataaatg gagactttgg ttactatgag ttctaaatca gaagtaaagc 57601 acaaaggttg ctggttgcta aggcaacaat tgtaagcaat tttctattgg ctcaagaacc 57661 agctaagaag gaaaaatttt gaaatgaggc aggagagtga gacatgttca gcccctttca 57721 gaaagtaagt tgttagaggg agagctttct ttcctttcct ctcctttcct tttcttttat 57781 ttccttccct ctccttccct tccctcccct cctttcttct tctttctcaa ccacacacag 57841 caacatggga gtgcaagaat gaggtcagtg cagaacctgc cctccatttg ctcaccaatg 57901 aatagagacc acatagagac agagataaat atctggcata tactaggctc acaatacata 57961 attttaacga aggaaggaag gaaggaagga aagtgaacca gcagagggat gtgcaaggtg 58021 tagtatttaa ctcttagaga ggagcaatca ttttacacac attttctact ataaaggaaa 58081 tacacagaat ttcaaaaatg gaaggaaact cggtggatgt tctattcaat ttcatgcaca 58141 acccatgaat tgtacccagt gcatgaatct acaccctgct gagaatgaga gagatgggca 58201 ccagtttctt ggctgatgag aagactgaaa gaaagacctc atgcagaggt ggcagtgctt 58261 atagcttgat ggttgaaggg cggccctctt ggatggctca gctgctgtct gtgggcttca 58321 cttccactca tgacatccag agtttcctct ggttccagcc cattttatgc aaggattcca 58381 ctttcttcat gagagcctaa aatgtgtcaa tctagtgtaa acactttccc ttctgcacag 58441 aggagaatct gtaagtagca tctggtggca cttgttctat ttttctctga cctcattctg 58501 aggcagtccc attagcctca tcagagaaac tcagatggtt ggggctgggg tggtgaggga 58561 ggatgtagct acagctctct gcaatcagaa atcacatttc tcccctggta cttaattttc 58621 tttcctcaga ctgtttttga gatttctgtc tttattgatt ttctgcagtt tgattctgat 58681 gtgtctaggt gtgtttttct ttttatttat cctgcttggg gttacatgga attcttggaa 58741 ctgtggatgg attgtttcgt tagtttagaa aaatttcagc cagtatctct acaaatattt 58801 ttttctgcct gattatcttt ctccccttct tcaggaactc ccattatatg aaataatgtt 58861 tgatattgtc ctatggagct tggatcctct atttttttca cccctttttt ctctttgtgt 58921 ttaagtttgg atcattttta ttgccccgtt ttcaacttta ttggttattc cctgatatat 58981 tcattctgtt aataagttca ttttaaaaag tcttctttcc ttatattgtt atttcgattt 59041 ctaacatttc cactggcttt tttaaaaagt ttccatctcg ctaatgaaat tctccattca 59101 ttgatgcaca ctgtccacct tttccactag cttctttaac atacttagta tagatacttt 59161 aaagtcttgt tggataattc taacatctga gcatctctaa atttggttct atgacttttt 59221 tcttatgatg ataagtcata tttttccctt tctcatgtgt cttataattt ttcattaatg 59281 ctgggcattg tgagtaaaag gaccagtaga gacaggtgaa tcacacctat gtccagaaaa 59341 gagcattgcc tctgccaggc tattagaatg agggtgtgtg tgagtcaatc tagtctgtat 59401 taatagtaga tttgggcttt gttgttgctt taattacata cattatgcca tagtatagtc 59461 ctttttagga gtctgttttc atccattaac aaaagcttca caggcctctc tgatattatt 59521 ttttaatttc tagataatca tgatatttct tgatgaccaa tggctcttac cccacataca 59581 cttatttggc atacagcata caaataatta ttgcaacaaa taattaatgt gatttatttg 59641 tatcctactc catctctgct ccacttctga taaaaagggc tactgggaaa taaatggcca 59701 gcagaaagaa gaaaaaaaaa tctaatccct tgggtgatct gtgctctgaa tgattgaagg 59761 tggggcagtc cagctgagga gataagaccc aaattaaccc atataaaggt aactaaaaca 59821 ccaggcattg caaaacagtg caggcattaa atgtttggga atgaatctca attcaaaaaa 59881 cattatctgt gagcctattc tgtgctaaat gctgtactat gggtgttgag ggtacaggag 59941 aggttatatg gtcaggagcg tttagagaag gtctcacaaa ggccatgaga cattaagatc 60001 accatttttg ggacttgaag acagtaaaga tcatgtaccc caaaggtttc caaatggttg 60061 gaattgtctg tatagatttg taaaactcca gctccctggc tctcaaatct ggagattctg 60121 attcagtagg tctggcgtgg gccctggagt ctgcatttta aaaactgttc caagtgattc 60181 gagaacacag aaccactgaa ccaaaatcct tataagtaag cccagaaaaa aggattgatt 60241 tgcacatggc cgcacagctt gcatggcagc aaagccagag ctcaaaccac ataatgataa 60301 ccacttttat gtatcaagtg ctttctgtgt gccaggcaat gtcttatgca ctttacgtat 60361 aatcacattt aatcctcata gcaatcgtat gggattacca tctttatcat catttccatt 60421 ttacagaatc cttagaaacc aaggcttaga aaggttatat tcgtgcctaa gattacacag 60481 caaatacgtg gcagagctca gatttgaact ccaaagccta ggcctttaac cattacatgc 60541 attgactctc aggcttttgc ttagcactag cagtgaactc aaactcccgg cagagtccag 60601 ggagaaaaga gcaggtgcat agctgcaagt ctcttgagaa agacacagaa ggcaatgtgt 60661 tttggcgtgt acgttttatc tggggagagg gtggatagct atttccacat tctagagggg 60721 agtcttctct gaaacctgcc ctgttgccaa ctaagcagcc tcctccccac gaagtaggtt 60781 ttaattggga gtttggcacc agcctcgggt gatttaatgg gatttgatgg gcatcttttc 60841 ctcaaactgg aatttcacaa gcactcatcc tctgggatta ccttctctgc cttcttttcg 60901 caagaaagaa gctctttgtg tgccttataa aagaatcaga gtcaaaggag aaaagctgtc 60961 gctgaccgtt cacacctcct gccgcacaca cccactctcc taaacacaca caggaacata 61021 cgttccctaa ggtcctgttt gtttggtgaa tgttttaaaa taaaatttaa tcctgtaaga 61081 ttttagagaa aagcatttct acttcaaggc attttgaaac ccattgaaaa aacagatgaa 61141 tgagattcag gtgcccggaa actaaagagt ctgctaaagc tgtcctctct gcactgtagg 61201 gagagaaatc ttgcattcct ggttgctgtc acggctgggc catggcaggt gaaggattta 61261 ggggacatgc tgggcttgag ccctcgcccc cctgtttccc tgatgtgtga tcatgggcca 61321 gatattatat gagagccaga tgccaacttc tcccagccac agttttctca tctgcagcat 61381 agcaatatcc tcatgtggtt gctgggtaga ttaaatgaag agtctggcct ggactgactg 61441 atcaatcaat gactgcaatt attggccagg catggtgact catgcctgtt atcccagcac 61501 tttgggaggc ctaggtgggc agatcacctg aggtcaggag ttcaagacca gcctggccaa

61561 catggcgaaa ccccatctct actaaaaata caaaaattaa cccggcatgg tggcgggtgc

61621 ctgtaatccc agctactcgg gaggctgagg caggaaaacc acttgagccc aggaggcgga

61681 ggttgcagtg agcccagatt aggcctctgg gcgatggagc cagtctctgt ctccaaaaaa

61741 agaaaaagat agcaattatt accatattaa gggtgatcct gggccatcag acttgaatta

61801 atttctcacc aaccccctag atctttctcc ctcccataca aagtatctta tgagtagccc

61861 aaaggggaca aggagcacgg ctgacaagga gagggtttgt gctccacttg ggggtagttc

61921 ctaatggggt ggatccttag tgagtgcatc ttggcataca aggaaggcag agatgctcct

61981 ggacccaccc aggtgagaaa actgaggttc agagaggtta ggtcatttgt acaaaggctg

62041 accagtaagt ggtggtgctg gaatttaaac tgtagttgat ttcacgttaa aagcccatga

62101 ttctctgtgc tgcattaaag gttcagtgga tggggacagg aaaagggaga gagatgggcc

62161 ttctaggtct tctaggtgtg gagaacagct cgagacagca taggaatggg aacgtagaag

62221 acagataagg gagttcatag gagacgctgc tggcttgggg aggggacagg aaggaagagt

62281 cagctagcct gggttctagt ctttgccctg ctgcactcta gctataggag cttggagcag

62341 tttcccagcc tctctgagct ctagtttacc taacaacaaa gtgggactta ccttttcccg

62401 aggtagaaat ggaaatggga gtgagcattt ggcacattgc aaagtgcccc caggtgagca

62461 gttctgcctc tatttcgatg caagggaact cgagctgcca ctcagccctc aggcacgctg

62521 tgctctagga ctcaggaggg ttgggtgagc ttctgggggt cctgcgcctg ccttcacgtc

62581 ttgctctgct cccacagggt gggagaatgt ctatggcttt gacatgacct gcatccggga

62641 cgtggccatg aaggagcctc tagtggacat cgtggatcca aagcaagtgg tgaccaatgc

62701 ctgtttgata aaggtctgga cactcatccg gggtggacct gggtgtgctg ggagccccgc

62761 tgtgccaccc tggagtccag gcaatgccgg ctcctgcaca gcccccacct ggtgaggcaa

62821 ggctgccttg gccagagcct gtgatgctcc ctaagctcaa gtcaaaagct ggcagtccgc

62881 ctggacacag ccactgagag agtggctcca tggtggcacg gatgtgggag ggccccagca

62941 caggggccct ggtggcgtgc agaagggtgg gggtgcaggg aagagagggg cattgcagga

63001 gaggacacct ggaagaggag agcgtgctca ggtttggggc agttggtcca ttcagaggta

63061 gacgtctctc ttagggaaga aatccaggac ctcagtatgc tgtgtaatca tcatcatgct

63121 cttgcctcca cacacacctt tgccccagcg gcctgccaga tagagcttcc agctgcccct

63181 tcctgagcgt ccctgttcat gctctcgcct ccacatacac ctttgcccca gcggcctgcc

63241 agatagagct tccagctgcc ccttcctgag cgtccctgtt tgtacatgct ctaaaccaag

63301 tgtgtccaac ctgcatcctc tgggccacat gtggtccagg atggctttga atgcaaccca

63361 acacaaattc gtaaacttaa aacattaaga gacttttttg tgggattttt tttttagctc

63421 attagctatc attagtgtta gtgtatttta tgtgtggccc aagacagttc ttcttctaat

63481 gtgacccacg gtagccaaaa gattagacac gcctgctcta aacacctttg cccgaggctt

63541 ccttcagtgc agatgaagaa cagctgctca gcgtctttgc cacaccaatc cctagtatat

63601 tcttattatt aaaaattcaa acatgtccag ttagatagaa taaaggtgaa aggtgccctc

63661 cgcctccctc cagccccatc ctcctccaga ggtaaccact gttcacaggc tgggttgcct

63721 cttccagtcc tttttgtatg catttgcatt atatatgcta atatattatg ttgaaccata

63781 taaaactatt gatatttgac agttttttaa aatagagaca tcaatttcat ataattcaag

63841 ccaaaaaaat tttttttgag acagaatctc actctgtcac ccagactgga gtgcagtggc

63901 acaatcacag ctcactgcaa tctcgactaa ctgaacagtt tcatgtacca caagctattt

63961 tttttttgag acaggatctc tttctctctc tgtcacccag gttgaagtgc agtggtgtga

64021 taatagctca ctgcagcctc actgaggctc aggtgatttt cctgtcttag cctcctgagt

64081 agctgaaact acggctacgt gccaccaggc atggctaatt tttttttttt tgtattaatg

64141 gggtttggcc atgttgccca ggctggtctc aaactcctgg gcttaagtga tccacccacc

64201 tcagcttccc aagtgctggg atgacagaca tgtgctacca cgcccagccc aggttaattt

64261 ttaaattcaa aaatcagccc acctgagtct catcttgcta acatgccggc ctactgtgct

64321 cctgcacgca tcattctttt tctgaaagta tcggggcagg gtactggact ggaatattta

64381 tagtaggata aagggattgg agttcagggc cactaaggac gggggtgggg gaggtttctg

64441 aaagactgac acaactgctg ctttgcccat gtgagaactg tcctttgtcc tggacacaag

64501 ccttgctagg aagaactgca cccgttgggc tggagtatca ctgtggactt tagaaaggtc

64561 ctcacagggc aaataaacct agaatgaacc tcatcagacc ccatcagatg ccccctctct

64621 ttagtagcat cctgcctgag aggtttggct ttgagtctaa gcctcagact ctccattcac

64681 agggttctca ctacttcatt cagccttttc tgggtccagg caggattaat tgtgagcaaa

64741 tgtgYccttt tgtttctttc taccagtccc tctgtccctg aagcctcttc ctccttgcca

64801 tcctaaacaa gaacaaggaa agtatgcccc cagcaagaag ctcacccata gtacaaggca

64861 cttctgtaaa tgtagaatag atagaagtcc actagtgcaa ctgaatttgc caaaatgaca

64921 tgtggcagtg atatttacca ttaggcatct gcacgtactg gcttcagctt ggggataaaa

64981 ttccttcaRt attcttggac cccaggttgc tctctgcccc tgacccaggc cccattggca

65041 ggtgtagcca ctgcatttct gtttgcactg ccggacacgt cagccactgt cctggccctc

65101 tccactcccc aggcaagaac tagcaggggc ctttcagttg gttagacctg agcatatcca

65161 ggggcaaagc agccaaggag cggctggagg ggtgtgtgtt ccgtacactc cttatgaaaa

65221 ctcccggggc tctggttctg tctcaggact cgtgacctgt gatgattttc tgtcccacgc

65281 tggtcccttt cttcctctgt gttcctgaga aggatgacga ttgtctgtgt ttgcttctgc

65341 ttccaggaga gcccttccgc cagctctctc ctgctgatgt gctaggcaac atcttgccga

65401 gcctgttggg aaaacacttg cccttcttca cacacttaat tgctattttc atcgctatta 65461 acattgcaga gtgtgacact ttattataat taaggttcta ttttaaccag acttctgctc

65521 cgagacatcc atttctaaca ttgtttaacg gtggggatcg cagcggccag gggcacttct

65581 gagtaattta tgctggtgaa gccctctgct tcaagcgggt cacctgaggc caagtcagtg

65641 ggtctccctg gggtctcaga gctgctgttt ctgctgcaga aaagaggaag cctcctagtc

65701 gaggggctgg gctctgggga gtcagggtaa ctggggctga tttggttggg ggttggggaa

65761 cctgagccca gaggaccttt gtgtttttga agcctagcta cagctgatcc catcctcaca

65821 gatggcctgg acccccattc caaaagacca cctgccctta ttgttgccat tataatgtgc

65881 ggcttcaata cttttggtcc taaaggcttt tgttctatca gaggcctcta ttaagatgca

65941 aatgtctcag ggatctattg aaagctgtca gctacaagag ttgatagctg acattttgtt

66001 gatggacatc tgacagcaag atcctttaga ggtggaattc ctgccagatg gggggtgcgt

66061 gtgcgtgtgt gtgtgtgtgt gtgtgtgtgt gtgtacgcgt gcgcatgcgg gatagaagga

66121 gaaagtaacc acgtctagat tgtaagccat aaggaatcat tgaaggttat agatccagag

66181 actgacacag tctggatgaa cctgagttac gaaagagggg cctaggcaaa gaagtaagtc

66241 ttcaagcagg gagacctgtt ctgagaagaa gattgatgag tcaacacata ttgctgtgta

66301 ttaggtgctg ctgtgcactg aggatacaca ggacaatgag gtgtaacttc tgccactgaa

66361 ggcttcagtg tatcggccag ggcaagggcg aaggtggtga gactgcgata tgagccagaa

66421 gtgagattgg aaggccatgc tacactggtg acggagggaa ccaagaaaga aagataccag

66481 ggaccttgga aagagcctgg agcctggctg attggccctg agaaggtgat ggaaaagtca

66541 gtaagggtag acactgtgat gccattaaca acaatacagg caaccaaggc ttgtccgaag

66601 agtttttgag ctggaggaca cctgtggaca gcatgtggcc atgtggctgg gagggataat

66661 gagcattatg aaggctgaca tatactcagt ctaaaacgtt tcctagattt gagcaatggc

66721 ccacgctaac agatgacatg taatgaagga cccctcccct tgagggatgt ggtggaggaa

66781 ggggcttggc cgacctaaat gcaagctgaR ccagcagtgt gctccttggg aacacaggct

66841 gctataagta tgtgccaatg gaaggacgtg gaggacctga tgtggtcagt ataactctca

66901 gttttgcaag tggcaggacc cacccagagg agaaaggcca gggtgatgag cggtcagaca

66961 tcacgactta tgaggaatga ataaaaagcc agagatagct tgcattggag aagaaaaggt

67021 ttaagggacc tgtgtgaatt ggaacacaca tttggcttct tctgtgggtg gaagttacag

67081 agggatgagt gtgaactttc ttcattagtt ttgaagaagg acctaatgac tggagatgcc

67141 aggacgtgga ctgatctgcc tggcagatgg tgaattctcc atccctaaag gtgttcagca

67201 agcactaggt gggtgctcag caagcactag atggccacta aagaggaggt tcttgccttg

67261 gataaaaggc tcagcttaag aagatgggct ttataatccc atcaaattct gcatgcttga

67321 ccaagggctc accattcaat tagttcttgt tccccttctc tgggctctag aaacacagtg

67381 taattggcat ttgaatgtga cctcaccaag ggcctcccac attcccctaa acctacaatc

67441 tcaccttctt cccaatcaac agtcagagag cttcagcttc cacagaagat gtcatggcta

67501 cacaccccag atcctaggag gactctgatc tcattggttc ccttaaccac tttttctctg

67561 tccatccctg tggagttagg acttctcttt gaaggcccca ggatagtttg cgtctgtttt

67621 tcctttattt atcctggaaa tacattgaga caaaagccat ttcatcgctt tgctggtctt

67681 gttttcctac cctctggtcc ctctctccta attcctacta ataattccat cttccaggcc

67741 tcaggaggtc cctgtggaac caaccaggca tacagatggc cttctggctc ttacagagtt

67801 ttcaggacag aggtccttgc tgcgcaacct tgactaatgg gaagttcttc cttgggcctc

67861 actagaatct gtcaggatgc ctcttgggcc ctagtaggtt tgccctgcct cacggggcca

67921 gcaagcagca ggccagcatt cttccataga aaagaacagc acagtgcaga cgtctttcaa

67981 ttccacctgc tccccatgcg agattgattt tcagccactt tccagttgaa attcttaaga

68041 gttattagtt cttcatgttc cacgttcccc agccagaact gaaaattctc acttcttatt

68101 ttcccctttt atttattttt gaaaacagtc cagccttgtt aaaaatggcc agcagaactt

68161 tcctaagctc tgtctgtgac tttgtgggct caggtcctta ctcctaatgt catccttgat

68221 gcctcctatt gctgggaact tgcgtatcaa aaaattgggg aaggagtagt ctggttcatc

68281 tacatcactg gagggcctga taaaacacag attgctgttt tggtccagca ggtctgcccc

68341 cctcagaatt tgcccccagg tactgttgat gctgatattt cagggaccac attttaagag

68401 cgatggatgg agcagtgcct gggtggacca ctcgaggctg ctctgacagg tgaagggatg

68461 cattgtctaa ttaaccctcc tgttctctcc cttccccatc atccccctgt agccccaaac

68521 cctggaagat ttatcttccg aattctgctc ccctcaggtt ttgattcaaa tccatttgca

68581 ccattgcttg agcacactcc accctagaaa ggatggagga ggtgattggg agggcggtgg

68641 ggagcctggg aaatcacccc aagaataaag atatccctca gagagctgac agaccacagt

68701 ctctcacaga acgaggctgc tgaccgggac ccagacttgg tggaggcgat aagttcccgg

68761 cattctctct tctctgggct gcaggaggtg gacatttaca cagtgaagac ggaagagcta

68821 tcgttcacat ctgcattctg cctgcagata cagcgcaacg actacgtcca cgccctggtc

68881 acctatttta atattgaatt taccaagtgc cacaagaaaa tggggttttc cacaggtgag

68941 ctgtttgttg cttcccagag cctcctccct ctcccatgct tcctcaagtc tttgtggggt

69001 gaccagagct ggccttgact tggggagaag gggctgggtg ttagctgggt gacacctatc

69061 aaccctctcc agccatggag gaaccatgca tccctatatt tgtgctgtcc aaggagaagg

69121 taaataatgt tgtggttgtt acagcacaag ttgagagtgt gttggatgag ggagaggcag

69181 gaggtagggc tcatggaggg gccccaagcc ctttcaaagg catatttgtt caggtagcat

69241 tttctgagca cattctgtgt ggtgggtatg gatggagttg aataagccta gtctgcactg

6g301 ccatgcctct gtgcaggaca cagcctgtct tgcagcagcc tgcacactgg tctctatgtc

69361 tccttccctt ctcccttact ttcacaccaa cccatccttc attaaatctc tgttggtgtt 69421 cccccaagat caccccactg ctactcccac tcccaaatcc cagccccgct tacgaggtgc

69481 ctcgctgcct gcagtagata agcctggcaa atggggatcc catggcctgg ccctggccca

69541 ctctccagcc tcattcctca ccacccctct tggccgagcc ctgtcccgtc gctgctaccc

69601 cacaggtggc ccagctacac cgagctcctt gctgacttct aaactcagtg aggcctcttc

69661 attctctggg ccatggcttc tacacacacc agcccttgcc tatccaggtg tgccctggag

69721 gtgggagggg ccttagtcag aggctctcat catcccctct tctcctgtat cagtctgtga

69781 gggcagccat aacaaaatac ccaggcttgg gggcttaacc acacatgcag ttctggaggc

69841 tggaagtcca aaggcaaggt gtcagcaggg tggatttctg gtgagggatc tcctcttgcc

69901 ttgtagttgt ccaccttctc actgtgtcct cacgtggtct ttcctctgtg ctcatgagcc

69961 cttggtggct ctatgtgtgt cctaattgcc tcttctaagg acaccagtca gattggatga

70021 agttaatcac ctcttttaaa gcccttttcc caaatacagt cacattctca ggtactgggg

70081 attaggactt caacatgaat ttggaggggg ggacaattca ggtggtaaca ccacccctga

70141 gccatctctt cacctggttt cctgtctcag ctcaggggtt acctgatccc cgctttccct

70201 ttgggtcaag gttcgatgtc ctcagggtga acctaacatc tcgtgcatgt gcctggcatg

70261 gtgatgtttc aagtgagaca catgcacaac agcaagaaga aatcaggaca aaagagtata

70321 aaaagtcaaa gaaagcattc tcacccccaa cccatcccac tcccactctt cagaggcaaa

70381 tattattatt aatgatttct tttgtatcat tccaccaaat ttcagtgagt gcacaagcac

70441 atgcRtatcc atagatgcct cttttttggc tttttatttt gaaataatta tagattcaca

70501 ggaagttgta aaaatagtac acagagttgt gtgaaccctt tgcccagctg ccccattgat

70561 ggtgtcttac gtaagcatag tacaatatca aaactacacc tttttaaaaa aacttaggtt

70621 ggatcctacc ctccacactg ccctcagcta ccttttcttt atttaacaac gttatcttgg

70681 tgatactctc atagcctcac agagatacct agcttctttt tttaaacaac cacacaggat

70741 tccaacacag ggcttgccat tatttattca gcattttcac cctttcttgc aactgtcagt

70801 ctcctgcatg agtagggatc atatctcagt gatctctgca ttcctgtctt ctaaagcaca

70861 gttctaaaca aattgctcta agaagtgtat gatgatatga cccctgccct taagaatgtg

70921 ttcctattga gtcttcctgg gaattgggag catgtcatca gggggtgagg aggtgagtag

70981 ttgtatgtct agtaggggga gtgggaaggt gagttctacc agaaatcRag gacatgattc

71041 tttacttcca gaagccatga agaaaatgat gctttttttt tttttttttt tttttttttc

71101 tcagagacaa ggtctcactc tgtctcccag gctggagtgc agtggcacaa tcatagctca

71161 ctgcagcctt gacctcctgg gctcaagcga tcctcctgcc ttagccaccc aagtagctgg

71221 gactacaggc acatgccacc atgcctggat actttttaat tttttttttt ttttggtaga

71281 gatggggtct tgcctcattg cccaggctgg tctcaatgat tctcttttac ctatggaaag

71341 agagggcaag agacagattt atctcttcat agaaaggctt ttcccagaac cagtgcctcc

71401 tgattactaa gattgggact tttggtctcc gtcagccagg cagtgctggt gctttcctgc

71461 cctgatctgg gtcattatca gctgctgccc tcctcacagg agcagtacat gtcttcccag

71521 tgggcaggag cagccaggag ggggaaggtg gattttactt tgatcttgaa ggattgggaa

71581 gactgtgcct agcaatggtg agagtagggg tagtgaggga gctggggagg agccttcttg

71641 gggacagtgg ctgtgattgg aagctaagga tgaagtcata ggagctggct ctgcctattc

71701 catcaccagg atgatgtcta acccagagcc tgccctgctg atgagaaagt ccatgggcaa

71761 ggatgctctg ggaaaagttc taagtttcca aaccccaggc tctatccctg cagctctcag

71821 ccatagtttt attttccttg agatgatcta ttaatatttc tagtctccaa agtcaagcag

71881 acagcctgct ggaccctgtc tagagatggc tccctggctc tggggtgtta gggatgacat

71941 tcttcatggt cccatgtgga ggagcctgga ttaagctcac atccagaatc aagacatcgg

72001 ctctgggctg cctgaaagat ggcgaggatt tgccctgagt gttgaaggct ctaacccagt

72061 ggctttcctt cctagtcttt ggtcacaccc ccaccacagt cctacgtggc tcaaagacca

72121 aggatctaaa cccagttgtg agcctactcc tctttttgca attatagtgt tatgcctcct

72181 cccttttgca cagaattcta caaacttagg ttctgaaaga catttggagg tcctacagtc

72241 tccagtttgt catgccttgg ggaagtggtt ctcaaagtgt ggttcctgga cgggtaacac

72301 cagtatcacc tgggaaattg ttagaattgc aaattcttga gcctcaccct ggacctcctg

72361 aatcagaaac tctgggggtg ggggccagcc gtctgtgtct taacaagacc tccaggtgat

72421 tgcgatgcat gctccagctt aaggaccact gcctctgtgc aagactgccc tgaaccagag

72481 ggttgagaat ttgaccaatg ttgactttct tctggaaagg ctattccatc tcctcactca

72541 ggtataccct caggcctcac caagactctt tgctttctgg ctgacgtaga tccctcttct

72601 tggcacatgc ctatatgggt agcaatgggg gtgggagaat actttgttga gttgctttct

72661 cagccacctt cgcgtgtcag cgtgggggct ctgtttctag caggtagcaa acttctttcc

72721 cagttcatgt gggttagcag tggggtatac tcagaccatc tatattctga caactgaccg

72781 agtaaccctt tctgttttta tggatctcag atgcacagac ttagattaat cctaattctt

72841 ggctcatgcc atatgtcatt attggaccat tcatggttca ctttttttgc taatttatat

72901 attaattata tataattata ttatatatta atataatgaa tatccatgaa ctcaccacat

72961 aactcagcaa ctagaatata aattaattac tattaactag aatgtaaata gtaactagaa

73021 tgaattaata aatactaaca aaataaatta ataaatacta ataaatttat tagtattact

73081 attagaaggt aaatacatta gttaatatta aaaataaatt gtttttaact aaaatataaa

73141 tattgactag aaagacatgg taataactgt aatataatta taattaaatg taaatcaatt

73201 aatgcatatt tgcattaatt tgcttacact tattgattcg agctatgccc tgactcaatg

73261 actgaaatgc tgccaacacc tctgcatctt cctggatgcc ccaccccatc ccacctcccg

73321 tatcgcctcc agatgaacat tatcctgaat tttgtgttcc ttattccctt gctatttatg 73381 aaaagtttta tcacatggat gtgtgtgcct aaacaaggta ttgtttggtc tcagctgttt 73441 ttgaacttga tgcaaagtgt agcctgctgt gtgtggtccc tctgcatcaa cccccaactg 73501 agtcttctgt tctcagccca gtggtagcgc gctctgcggg ccacttagaa acacatccca 73561 taccgcacag cctgaaaaat gatcccttct aatgactctg acgtctctgc agctccaggc 73621 agaagctgtc acaaataggc acagacagcc agggttccag gctgtggcag ccagtgggca 73681 cggtgccccc cccaccacaa cacatcctca gtggggtggg ggtagaagtg ggaactgggg 73741 cccctggggc tgctgtgtaa tccaggaaag ccaggtagca ggtggaaggg caggagcccc 73801 agcagaagca ggcctgggtg caagccctgg ttttttcagg tatcagcaag gtaggcagat 73861 cagacattgg aaaggacttt gggcaagttt actttctgcg ccttgggctc aggcagctcc 73921 tttctgccat tgacatcctg tgacattgag tcattttccc acattaaaga agcttcttgg 73981 tgcatagtcc tcaattctcc aaaaggccta tgaattctct agagaatata attccaaact 74041 tacagctaga aaaattatat cccagaaagg acgaccagcc acttagccat tggtcagtga 74101 gatgggaagc aggattccat tccctttcca aaagcaccag gaaaactctg gtgagaggcc 74161 agtccctgcc atttgtaccc tcagctccct gtgttcccaa gccccatcct tggtcatagt 74221 gcccacccta cttctcacta tttgcctgaa tgtcttctca ctgaggctgt atgatcgggg 74281 gaggagggga caaagtggtg ttcatcccgt ttgctgttcc ccaattctac agccataccc 74341 ggcctgtggc aggcatccta agtggaagtc tgtggaatgg tgaatgaatg cactgcacta 74401 ggaatgctgc aggcagtact ggtcatgctc acttcaaaat gtagaagaaa agctgcctaa 74461 agcctagaat cagagagact gtgatgggga agggaactgt gggagggaga aaaggggtat 74521 gtggggccag aatgctaaga gcagggaggc atcttcagaa tggggaaggc tgaaagccag 74581 ttgtacaatc tggatggtca tagatggggt tggggcaggg gaagggaaag ctttcctccc 74641 tgacaaggag aactctagat gttgtccaca accctttcct gagcgcccac ccttgtgcac 74701 ggtgacattc tggatgtttt ccaagacatt ctccaccagt agagagaggc ggcatatctt 74761 tgcagaccag agccatagtt gatggactaa taaaatcata taccactcta atgaccaaag 74821 acttgcctga tgcaatggct tagtaagtcc ctaacatggg cctaatatgt tttaggtagg 74881 gtggccatgt aacgcatctt tccattaagg acacgtatgc aggtgaaagg gagacctatt 74941 aatcattatg ccaggaaaac agatgtgaac tggaactgtc ccaggcacag caggaggttt 75001 gatcaccctt agtctatgat cctttccctt tctcatctca tctcatcctc acaatacgtc 75061 aggaggtgaa tatcatgagc catattctgc agatgtggaa aaggagcccc aggtcacatc 75121 gcatgtcagt ggcaaagtgg acactggaca cggggctatt gtcacctaat taatgtcttt 75181 cccactctac cttcccaaag gaggtcagga gatgcactgc gattcagcca tggctgtgtg 75241 tctacgtcac ctgcccctcc acgcccccca gaattactga cttcaaatct cttggagtag 75301 aatcaaaaca ttgactttta ctcagcttct cctgggcact ttgatggaga atcaggattg 75361 ggaaaactgg tttagacaat tactccatgg ctaatgggcc catcatggaa acgagatgtt 75421 tatggatgtt cttaaccctt tgatgttgat atcaaggaaa ataatcatct tcctccaact 75481 caaagtcggc atgttttggg gactaccatc agaggcagac cccatggctg acaaatctgg 75541 gccaggaagt ctctgggggt ctcataaggc atcggattag gtgacagaag gaggctgctt 75601 gaaatccctt tgcctgaagg tctttaggaa caggagagag acacctgtct gagctggtgt 75661 aggtggaagt gggggcgaga gtgctgtcag tcatacactg acagtctcca cacataacca 75721 ggaactatct tttgactatt tagaggtagc tgggagagat ggttgttggg agcaggtgga 75781 ctttgtctgc agacagcagt atgccctgaa ggccagaaag gctggatgtg ttcaggaacc 75841 caggcagggt ctgaaaggga tagactgcac attcatgatc ctccttccct ttccaaatgt 75901 gcaggctgca ctttctcccc atgaccttga gtttgcatcg atttcccaaa tgcacacacg 75961 gagggctact tgagtctctc tccaaaccac tgacatttga tcaagccagt tcattgtgaa 76021 gggcagagaa agacagactc ttcagtgctg ttaaaattgg ccttggggtt ttgaaagctc 76081 ttagaggtca cctggtctga gtcagtgcat gatcaagccc cagttggcgc tgtgtgaaca 76141 cctgccaggg tggacctcag gtggctcata tgattgtggg acagctctaa ttcttggtaa 76201 attaaaaatc tgccttctaa tcatgcctag tgactagcct ttgttctgcc cccaaagcca 76261 tgataaggcc acatgtaagt ctttccatgt gacagctttt gaagtgtttt gaagaccctt 76321 atcttatccc caagtcttct catctttatc cttagtccta aaaaaaaaaa aaaaagaaat 76381 cctggtagag gaatgcaaca gcccaaacca agaggaactt cctgtaataa gatgggttct 76441 tctgcagtct gtagattcca aaggccccca gggtaactgg agtacattga actccagtac 76501 gagtacattg aagcactaca gacatttgct ctttgggttc ttaccatcat tcatttattc 76561 aatactcgta gatctaccaa gcacagaggc aggcaccgag gaagcaaggc tggcccggtc 76621 cctgccctca tggagcttgc agtccatRga ggatgcagac aaacggggat ggggggaagg 76681 catttatctt gtgtgacagg caccgcaata acaggagctc agggtgcctt gggagctctc 76741 agtccaggtt ttgcgggtca ggcaaggctt cccagaggaa ggatgaggaa gagagaggct 76801 ggaaaggagg gagaggaagg atttcagaga cagctgctgg caaggacggt ggcctctgag 76861 gcagaactcc tcacatttaa ctggagaata tatcgtgtgc tgagagggga gggaagagac 76921 tcaatggcag atatggggga ggcgcaagta ccactatggc tttgggtcat acaggatgaa 76981 tgagctgtgg gccagcatta gggctgtgga acaagaacca tccctcattt ctttctgatc 77041 tggttaggaa gatacacctg aaaccctaca gcaggtctgg gccaaggtgc taggtttagt 77101 tccccgtgca cagagaagca ggcagggaaa gctctttttt tttttttttt tttttgagac 77161 agggtctcac tcactggttt gcacccaggc tagagtgcag tggtatagtc acagctcact 77221 gcaaccttga actcccaggc tcaatgcatc ctcctgcttc agcctcctga gtagctggga 77281 ccacagatgt gtgctaccac actcgcctag ttttctcatt atgttgccca ggctggtctt 77341 gaactcctgg gctcaaccag tcctcctgcc tcagcttcct gagtagctga ggttacagct

77401 atgagccact atgtgtgccc agcaggaaaa gctagttgta agattgagga ccaagtacct

77461 gccatatcag tggatctggg gaaactggtt tagctgtgga gtttgcatga atgatgtcat

77521 ttaaggggag ataggagggc ctactctaca aatctcttcc ccatactgtc tgaagatctt

77581 cattctgttg aactaattaa aaacagcagc atgttcagat gcatgtatgt ccatgcattt

77641 agtgggtgac agggtattcc tcatccatcc cttgctatga acttgtagta tcgggttgtt

77701 tgtcttctga tccccagcac tgaggagatg gggatgtgat gggaggagag gccactggga

77761 ctgagaggga gttctgatgg ggcttggagg aaggctataa ggactatgca cctgacccaa

77821 caagagtact ggggtgggtg gtttcagtga gtcccagggg aagcccagca acttctatgc

77881 agggtcccag cctcatccct ttggagactt cgtctctgac tctttcttcc cacctcccct

77941 gttctctcac Ycctcagccc ctgatgctcc ctacacccac tggaagcaga ccgtcttcta

78001 cttggaagat tacctcactg tccggagggg ggaggaaatc tacgggacca tatccatgaa

78061 gccaaatgcc aaaaatgtgg taagtgccga gggacataag gacataaggg agaagggccc

78121 cacagagctg gctcgctcag gacccacttg cccgggttct taagtgtctc atgaacagtc

78181 agaaacttac tgaggcaggc agtcggtagc cacatgtgga catgactagg cctaattgag

78241 ggactcaggc ttgacccctc aaaactccgc aaatagaggt tttccctggg tccaattctg

78301 gactgccttg gctttgaaga cagcttccag ctcttcctgt gaggggcttt caaataaatg

78361 ggtcctacct catttagtaa gagctgggcc aggagataag ctcctggtgg ctggaggatg

78421 tttggcgtgc atttcttcag ctggcctggt gcgagggaga cttgctggca ctttcggggc

78481 agccccaggt gtgggcatga gcgctaaaaa cgtctgcaga gtgctctgaa ggtcacctca

78541 cagaacactt aaccacccca atcagtttac ttccaggacg aactcggaac gttttgttat

78601 tagagcagga aggatttagg gagaaatgga agaacttcct gtgaggacaa ggaggcagca

78661 gaatggattc ctgtgggctg ttcaggggaa ccccttagcc agaaagcctt aagacgctgg

78721 tgctacccat ccctgtggtt ccaggagcag gtggtgccag agagtggggc tgtggcttca

78781 tacccagacg gccgcctgac ccttcgctct ctctctgcct tgcagcgaga cctcgatttc

78841 acagtagact tggattttaa gggacagctg tgtgaaacat ctgtatctaa tgactacaaa

78901 atgcgttagc acacgtggga agctgcagag agcaacgaga aaaggaactc tcacctcgat

78961 ctgccgtgcc gtcccaaaga ataccgtttg caggactaca cacttgaaaa ccagagtttt

79021 caactctgcc ttgaagattg gtgaactccc cagggctccc gtgggctctg ccactggaca

79081 gaaggcctcc agctcctccg ctctgccctg gtagcccttc acgaaggctt tgtgttgcca

79141 acaaagagcg acctggcgtg ctgtggctgg gccccgaggg tggaaacgta ttcgcgtctc

79201 cccgtctcct ccttaactgt gactctccgg gtcttctgag ttttgcatgc tgcgggtgtc

79261 taggacagat tgcttccact agaacctgga gacatagcat ctttgatagc ataagccaga

79321 ttatctgtgt gtgcggtggt gtgcgtgtgc gtgcatgtgt gaatgtgagc agcatagttg

79381 atatttaccc acaaacacct gtatatgcgt gcatatacaa ccaagtgggt agacctaggt

79441 gttctctcag aggggtgtgt gtgtgtgtgc gtgcgcgtgt gcctagaata tatattactc

79501 tcagaggaga ttctgttgct tttgaatagg aatttgtttt gtgattagtt cgccccttcc

79561 ccacccctta ccagatgtta agcagctatg aaacattctc tgtactagtt ctggtctcct

79621 tttgactgga ctgtggctct gaaccttgag catagtacca cggactccgt gggcgctcaa

79681 taaacacaca tgagaacaaa ctggtgggat ggctggttcc tggtgctgtg aagtgggagg

79741 gctgggggga agccagaggc catgatggag tggagactca agggcagcag cacctacgtg

79801 ggttcacgtt tgctccccag cagggaggtc agggctggtc taagagcatc tcccccatgg

79861 actctgaggg gtcctacctt agagggtaag gaggtcatgg agctggggtg ggggacagga

79921 gctaaccaag agtgtgccag aatggcaggc catgcatagc ctggagactg cttaggataa

79981 tgtccagcct tggtccgggc gtggtaacag cggaatctgt gaaggatgga aatgcaatgt

80041 actttgcagg gcgtggtgga Rtgttttgat ttggtctggt cttgggctat gctttagctt

80101 ccaagaccat gattctcatc tatgtcacct acctgggaag agacattcca ggtgggggaa

80161 ggaagagggg ccatttagag atgatgggtg gagctgatgg gatccaggaa gaaggaagat

80221 gcaggggaga cctcgggcct ggctttgcgt ggttggggag tgctggtgat ggcagagccc

80281 ctggataatg ataactgaac ccaatagcaa tggcctctgc acttccataa acttctgatg

80341 tccatggact ctgtcaattc catgaagcct tgggagttac acgcagaggc cttaccccag

80401 ccatttgcta gctgaggtgg gccaaggtct caagtcccag ttaatgtgcc ctcccctgcc

80461 ctgcactgat tcttccaagc ctcaggccca gaggctaaga ctgtcttttt tatacctaga

80521 gaaaaacaca gtgaaaatta tttaatgctt tttgtgtaca tgtattggga agaaaaatag

80581 agaaacttaa gagggcacag aagcaagtgt attagaggag agaggagatt gaaggaggac

80641 attggagtgg ggactccctc gggggcattc gagaactcag gagttggttt ccattgtagt

80701 gagagttggg gtcccctgga ttctgcctac tgacctggtt taactttggg caggaagctc

80761 attcaacctg gtgtaggatc ccatccatgg tcaaccagca aaatcccaca ttgtcaggag

80821 cccagtggag cggtcaagat gatggcctcc tgggagctcc aggcatttgg gtcctgcagg

80881 catccctgac actctgggac ctggggaggc tgctggggca ggaggcttag gggaggacca

80941 gaatgagcaa aggcccagca atctttcggg cctctctgac catcagagga gaagagggcc

81001 atcccagggg cctatcctgc acccaccccc atctttagct ttctggagtg gtacaagccc

81061 tgggctgccc caccaccacc cctccctgcc cctgggctgc agaagggaag cctgtaatgc

81121 ataagggatc aattccacag cagcctcctc ccacctgctc aggcgaatgc tccagtggga

81181 attatttccc tccgattcag tgggaaataa gcaatctctg ctttgaacag cctctgaatg

81241 gaagtcagtg catgagatgc ggtctcgaat gacaacagag atgctataaa gatgacttca 81301 ctgataaaac ctgttttttc ctcgactctt tgcctctttt acatttttga ggctgtacaa

81361 aaccctttag agactttctc gcctgtcact cttcccctgc tctggggaac tttgcccttc

81421 tattcccaac tcccttctcc caaaatgtgg tcctcttttg tgattgcatc tgggcttgtc

81481 tgtacagagg ccactctgtg cttgttccga agtccacgga ggcatggttt ctctcccctc

81541 ctaaaccaca agctccaagg gcggagacct gcctggagag agcagggtgc gggtggctgg

81601 taacagagtg gcagctgacc cagcacttgc ttgatcccat ggaatgtgcc catgagcacc

81661 tgccccccac ccaggacctg caggctccag cctcttctat ttgtgctcct tgggagatgc

81721 caatattttt tttactttca taaaaaccac cccatggagg ccatctaccc tagatacacc

81781 caagcctctg tcaactctgt gggcggaaat gaggccttag ccaggccctc catggaccca

81841 tctccgaagg ctccctctcc ccttgacgtc atacctgcaa tcccacctat agactccacc

81901 tcacttcaga cctcagtagt ggcatgaaat taagccagac atcttggccc gtctctgcac

81961 cgtgttcacc tggcctggaa tctgtccctg gcctaggggc agttctgatc acccggcatg

82021 tgccctgcct tgatctcctt gatctcacat agtatgggga ctctgtcttg tttttgcaaa

82081 tcccctcact accacactga cggccccagc ctggttttag gagccctctt cctgaagaaa

82141 catttttcag gacccctgct acctgcctgg gttcctgact agcatctctt tagatatctt

82201^" gtttctgagt acagctctac ctgggggcac ctagatttcc ctagaccgcc aggctgtggc

82261 atattatacc cagactccta ttttgttgtc tggtgacttc caacataagt ctgacttccc

82321 gaggacaggt gatctcctca gtacgtgtct aaccgtagtg gatgtgctga gctccaggcc

82381 tggagcctcc aatgtccccg tcccattgga agcaattagt ccatattcag caaaggctca

82441 gacacaacac attccagtat tggatactta ataggctcca ggcactgaac taggtagcag

82501 cagtatagca gagacagcag gcatcatgga actctgtggt tattagtgtc tagctaggct

82561 gggcctgctc ttgcctaaat ttcaagaaag taagttccct ctgccattgc ctaccagctc

82621 cagctctacc catctcatcc cgagggccag ccacagttct tagcccagct ctgcaacaca

82681 acctctgtca gagggggtgg tgagccatgt tgcttgttgg cttatctcag tcactaagcc

82741 ctagaaacag aaagagaacg tgcttgaatt tcctgctatc tgtgaattcc atggtggggt

82801 ggggggcagc ctgtcatttt cagagaatga cagtgctccg ggaggcccag ggcccttttt

82861 aaagctggca gtaagtcatt tctcacaaca gaagtgccaa agagagtgtg ccaaccatta

82921 gctgacactt aaggctagag agcagctgga gcaaacgggg cagagaaagc cctagcatgc

82981 gggtcaccag acccaggctc ctgctgtccc catttccaaa ggcaaccatc agccgccaca

83041 cagctctgct gcatgacatg agttttggag ccaaagaacc tagtcaactc cYggcactgc

83101 tgcttactaa cgacgtgatc ttgggcaagt cactgtgaga ctctatatct tcttctgctg

83161 aaaaggagac aactcagaat gaaatgaaat caatataaaa tgtgtttaaa aaaacaaagc

83221 acagtgaaat tctagtgata actgctgctt caatagccat tctgctctgg attgcaattc

83281 tgttcttgag aagcacattt

[0316] Following is a HRMT1L3 genomic nucleotide sequence that includes the HRMT1L3 SNP "HRMT1L3-AA" (SEQ ID NO: ).

ACAAAAATTGGGTTTTAAAAATTGATTTAGCTGCTTTGTTAAACTGAGGGGATTTTCCAAGAGTGGCCTTTTTTTTAAAAA AAAAAAAGAATTCCTAACTCTAGTACTTGTTAGAGGTACACTCACAAATTTAACTCTTCCCTGTCCCATAGAGGCTTCTCT AGGAGGGCGCACATTAGATGCCTGCTGTTTACAAGGAA[G/T]AGGGAAATTCTTAATGTCCTTCTCACGTTGTTCTAATT CTTCCCTCAAGTTTAGGTAAGGATTTAAGGGAGCATTGGGTTTAGCTTCTTCTTGACCCCCAGATTCCTCTTCCTCCGACT TTCCTGTTGCCCCCAGTCTCCCTGTCCTCTACTTTGTGACATGTATGGTGAGGGGGGCAAGCGTGTTGGGGAATCCCAGGG

[0317] Following is a HRMT1L3 genomic nucleotide sequence that includes the HRMT1L3 SNP "HRMT1L3-AB" (SEQ ID NO: ).

GGCAGGAGTCCTTGCCTGGGAGGATGCCGTTTTTCCCAAATGGTTATGGCTGCCCTTTTCATTATTCCCCTCTCTTCCCCA GTAAACAAAATATTCACGATTGACATTACCTTAGCCCAGGTACAAAAATTGGGTTTTAAAAATTGATTTAGCTGCTTTGTT AAACTGAGGGGATTTTCC[A/G]AGAGTGGCCTTTTTTTTAAAAAAAAAAAAGAATTCCTAACTCTAGTACTTGTTAGAGG TACACTCACAAATTTAACTCTTCCCTGTCCCATAGAGGCTTCTCTAGGAGGGCGCACATTAGATGCCTGCTGTTTACAAGG AAGAGGGAAATTCTTAATGTCCTTCTCACGTTGTTCTAATTCTTCCCTCAAGTTTAGGTAA

[0318] Following is a HRMT1L3 genomic nucleotide sequence that includes the HRMT1L3 SNP "HRMT1L3-AC" (SEQ ID NO: ).

CAGCCCCTTTTGAGTCTCCAGCACAGAGATCAATCCCTCCATCACGGGTGGTGACTAGACATCAGTCTTTT[C/G]GCAAA GGCAGCCCAATTTCGTGGAAGGCCGCTGGCCTTGAGGTGGGGGGGCTGGGTTTCGGTTTTCAGTCTGCCACAAAGTTGTGA TGCAGCCGTGGGCAAGTCACCACCCCTGTCTGGGCCTCAGCGTCTCTATCCATTGAATCGGTGTGGGTCTTGCTGTGATTT TTTTTGACGCCTTGCTCCTTTGTCCTATGCCCTTTCCAGATCGAATGCTCCAGTATTTCTGACTACTCAGAGAAGATCATT AAGGCCAACCACTTGGACAACAGTAAGACATACCTCTGAGTGTTTTCTCCTGGATGGAGGGGACGGGAAGCTCACACTTTC TTGTTGGGATGGCATAGCGGGAGGAGCGCAGAGCACTTGGACTTGGGGAGGTGGTGCACCCAGCTGAGGCCCCCGCCAGCA AGACTGCGGCCATGGGTACTGATGTTCCCCCCGACACCAGGCCAGCTGAGGATCACAGCCACCCCCTCTCCGCTTTTGGCA AGCCCTGCTTGTAGCTAAATCCCGAGTTGCCAGACCCTTTGCTTGTCC

[0319] Following is a HRMT1L3 genomic nucleotide sequence that includes the HRMT1L3 SNP "HRMT1L3-AD" (SEQ ID NO: ).

CAGCCCCTTTTGAGTCTCCAGCACAGAGATCAATCCCTCCATCACGGGTGGTGACTAGACATCAGTCTTTTCGCAAAGGCA GCCCAATTTCGTGGAAGGCCGCTGGCCTTGAGGTGGGGGGGCTGGGTTTCGGTTTTCAGTCTGCCACAAAGTTGTGATGCA GCCGTGGGCAAGTCACCACCCCTGTCTGGGCCTCAGCGTCTCTATCCATTGAATCGGTGTGGGTCTTGCTGTGATTTTTTT TGACGCCTTGCTCCTTTGTCCTATGCCCTTTCCAGATCGAATGCTCCAGTATTTCTGACTACTCAGAGAAGATCATTAAGG CCAACCACTTGGACAACAGTAAGACATACCTCTGAGTGTTTTCTCCTGGATGGAGGGGACGGGAAGCTCACACTTTCTTGT TGGGATGGCATAGCGGGAGGA[G/C]CGCAGAGCACTTGGACTTGGGGAGGTGGTGCACCCAGCTGAGGCCCCCGCCAGCA AGACTGCGGCCATGGGTACTGATGTTCCCCCCGACACCAGGCCAGCTGAGGATCACAGCCACCCCCTCTCCGCTTTTGGCA AGCCCTGCTTGTAGCTAAATCCCGAGTTGCCAGACCCTTTGCTTGTCC

[0320] Following are SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 and HRMT1L3 complementary DNA sequences (cDNAs; SEQ ID NO: 7, 8, 9, 10, 11 and 12, respectively). [0321] Following is a SPUVE cDNA sequence (SEQ ID NO: 7). NM_007173 [gi:21614539] Homo sapiens protease, serine, 23 (SPUVE), mRNA ggcaggcatgggagccgcgcgctctctcccggcgcccacacctgtctgagcggcgcagcgagccgcggcccgg gcgggctgctcggcgcggaacagtgc cggcatggcagggattccagggctcctcttccttctcttctttctg ctctgtgctgttgggcaagtgagcccttacagtgccccctggaaacccacttggcctgcataccgcctccctg tcgtcttgccccagtctaccctcaatttagccaagccagactttggagccgaagccaaattagaagtatcttc ttcatgtggaccccagtg cataagggaactccactgcccacttacgaagaggccaagcaatatctgtcttat gaaacgctc atgccaatggcagccgcacagagacgcaggtgggcatctacatcctcagcagtagtggagatg gggcccaacaccgagactcagggtcttcaggaaagtctcgaaggaagcggcagatt atggctatgacagcag gttcagcatttttgggaaggacttcc gctcaactaccctttctcaacatcagtgaagtta ccacgggctgc accggcaccctggtggcagagaagcatgtcctcacagctgcccactgcatacacgatggaaaaacctatgtga aaggaacccagaagcttcgagtgggcttcctaaagcccaagtttaaagatggtggtcgaggggccaacgactc cacttcagccatgcccgagcagatgaaatttcagtggatccgggtgaaacgcacccatgtgcccaagggttgg a caagggcaatgccaatgacatcggcatggattatgattatgccctcctggaactcaaaaagccccacaaga gaaaattt tgaagattggggtgagccctcctgc aagcagctgccagggggcagaattcacttctctggtta tgacaatgaccgaccaggcaatttggtg atcgcttctgtgacgtcaaagacgagacctatgacttgctctac cagcaatgcgatgcccagccaggggccagcgggtctggggtctatgtgaggatgtggaagagacagcagcaga agtgggagcgaaaaattattggcattttttcagggcaccagtgggtggacatgaatggttccccacaggattt caacgtggctgtcagaatcactcctctcaaatatgcccagatt gcta tggattaaaggaaactacctggat tgtagggaggggtgacacagtgttccctcctggcagcaattaagggtcttcatgttcttattttaggagaggc caaattgttttttgtcattggcgtgcacacgtgtgtgtgtgtgtgtgtgtgtgtgtaaggtgtcttataatct tttacctatttcttacaattgcaagatgactggctttactatttgaaaactggtttgtgtatcatatcatata tcatttaagcagtttgaaggcatacttttgcatagaaataaaaaaaatactgatttggggcaatgaggaatat ttgacaattaagttaatcttcacgtttttgcaaactttgatttttatt catctgaacttgtttcaaagattt atattaaatatttggcatacaagagatatga

[0322] Following is a GR1N3A cDNA sequence (SEQ ID NO: 8).

NM_133445 [gi:20143963] Homo sapiens glutamate receptor, ionotropic, N-methyl-D-aspartate 3A (GRIN3A), mRNA cagagaggaagtagcgagagaagagagaaaatgaagtcggcgctgggggagcctgcaggagggtggccaacag tggaggaaggtggatttggcttcttttccgcaccccgggcgtgaaagccctctccaacgcgaccccaggaaat aagtgggtctcgcctgggcagaaaaggaaaagaatccaggcgagagcgcgtcgctcctctgtcactgctgccc ccgaggaactccggctgcttc catcccggccgcctcgcggggccggacgcagtgcccgaggcgccctgcaga tggggcgggcagggaacgggcgctccagctgcgggtgacaggcgccggcccgcccgcctgcctgctcagcgca gtgaccgggcgggcagaggatgccaggcggagggacctgggagcgggatctgagactgccggaggcgcgctac gc ccaacttgcatggcctagagaccgctccagctcctgggaccgcttcaccgagtggagtgaagctgcgcgc gggacctggaggcggagacctcaggcagcggctgcagaggggcgagccgggcgcaggagggggcgcgctttct ccctgcgggtctcagtaatgaggagactgagtttgtggtggctgctgagcagggtctgtctgctgttgccgcc gccctgcgcactggtgctggccggggtgcccagctcctcctcgcacccgcagccctgccagatcctcaagcgc a cgggcacgcggtgagggtgggcgcggtgcacttgcagccctggaccaccgccccccgcgcggccagccgcg ctccggacgacagccgagcaggagcccagagggatgagccggagccagggactaggcggtccccggcgccctc gccgggcgcacgctggttggggagcaccctgcatggccgggggccgccgggctcccgtaagcccggggagggc gccagggcggaggccctgtggccacgggacgccctcctatttgccgtggacaacctgaaccgcgtggaagggc tgctaccctacaacctgtctttggaagtagtgatggccatcgaggcaggcctgggcgatctgccacttttgcc cttctcctcccctagttcgccatggagcagtgaccctttctccttcctgcaaagtgtgtgccataccgtggtg gtgcaaggggtgtcggcgctgc cgccttcccccagagccagggcgaaatgatggagctcgacttggtcagct tagtcctgcacattccagtgatcagcatcgtgcgccacgagtttccacgggagagtcagaatccccttcacct acaactgagtttagaaaattcattaagttctgatgctgatgtcactgtctcaatcctgaccatgaacaactgg tacaattttagcttgttgctgtgccaggaagactggaacatcaccgacttcctcctccttacccagaataatt ccaagttccaccttggttc atca caacatcaccgctaacctcccctccacccaggacctcttgagcttcct acagatccagcttgagagtattaagaacagcacacccacagtggtgatgtttggctgcgacatggaaagtatc cggcggattttcgaaattacaacccagtttgggg catgccccctgaacttcgttgggtgctgggagattccc agaatgtggaggaactgaggacagagggtctgcccttagggctcattgctcatggaaaaacaacacagtctgt ctttgagcactacgtacaagatgctatggagctggtcgcaagagctgtagccacagccaccatgatccaacca gaact gctctcattcccagcacgatgaactgcatggaggtggaaactacaaatctcacttcaggacaatatt ta caaggtttctagccaataccactttcagaggcctcagtggttccatcagagtaaaaggttccaccatcgt cagctcagaaaacaactttttcatctggaatcttcaacatgaccccatgggaaagccaatgtggacccgcttg ggcagctggcaggggggaaagattg catggacta ggaata ggccagagcaggcccagagacacaaaaccc act ccaacatccaagtaagctacacttgagagtggttaccctga tgagcatccttttgtcttcacaaggga ggtagatgatgaaggcttgtgccctgctggccaactctgtctagaccccatgactaatgactcttccacattg gacagcctttttagcagcctccatagcagtaatgatacagtgcccattaaattcaagaagtgctgctatggat attgcattgatc gc ggaaaagatagcagaagacatgaactttgacttcgacctc atattgtaggggatgg aaagt tggagcatggaaaaatgggcactggactgggctagtgggtgatctcctgagagggactgcccacatg gcagtcacttcctttagcatcaatactgcacggagccagg ga agatttcaccagccctttcttctccacca gcttgggcatcttagtgaggacccgagatacagcagctcccattggagccttca gtggccactccactggac aatgtggctggggatttttgtggctctgcacatcactgccgtcttcctcactctgtatgaatggaagagtcca tttggtttgactcccaaggggcgaaatagaagtaaagtcttctccttttcttcagccttgaacatctgttatg ccctcttgtttggcagaacagtggccatcaaacctccaaaatgttggactggaaggtttctaatgaacctttg ggccattttctgtatgttttgcctttccacatacacggcaaacttggctgctgtcatggtaggtgagaagatc ta gaagagctttctggaatacatgaccccaagttacatcatccttcccaaggattccgctttggaactgtcc gagaaagcagtgctgaagattatgtgagacaaagtttcccagagatgcatgaata atgagaaggtacaatgt tccagccacccctgatggagtggagtatctgaagaacgatccagagaaactagacgcct catca ggacaaa gcccttctggattatgaagtgtcaatagatgc gactgcaaacttctcactgtggggaagccatttgccatag aaggatacggcattggcctcccacccaactctccattgaccgccaacatatccgagctaatcagtcaatacaa gtcacatgggttta gga atgctccatgacaagtggtacagggtggttccctgtggcaagagaagttt gct gtcacggagactttgcaaatgggcatcaaacacttctctgggctctttgtgc gc gtgcattggatttggtc tgtccattttgaccaccattggtgagcacatagta acaggctgctgctaccacgaatcaaaaacaaatccaa gctgcaatactggctccacaccagccagagattacacagagcaataaataca catt atagaggaaaagcag cagcatttcaagaccaaacgtgtggaaaagaggtctaatgtgggaccccgtcagcttaccg atggaat ct ccaatctgagtcatgacaaccgacggaaatacatctttagtga gaggaaggacaaaaccagctgggcatcca gatccaccaggacatccccctccctccaaggagaagagagctccctgccttgcggaccaccaatgggaaagca gactccctaaatgt tctcggaactcagtgatgcaggaactctcagagctcgagaagcagattcaggtgatcc gtcaggagctgcagctggctgtgagcaggaaaacggagctggaggagta caaaggacaagtcggacttgtga gtcctaggtgaccacactgcttccctttctcagttcctgaccttcctctgagcccttgagacactttgtaatg ctcttttgtaactatcgacaaaggtgtggggaagctgaggtctaggtcttcttaaaggtcaagtctgctctcc ctcgcctaaagtgcagcagcagctcctctcaagctcactctctaggtctccagggtaggagtgtttttctagc aagaatcttagtcaggagtaagctctgtgcgagagatctgtgaataaccagataaccccagctgccgttaacc ttttcaccaggtgccacagtaatatttctggtttttagccctttctctgcactaccaacaagagataaaattg ttactcacacttatgtcttactgggttgctggttttcatcgtaacacagaacgaggttatctagggttg gc ttttgatacaactccccgatctagatttattcctacattctgaatggggagcaggtaagagcagagcacctcc cactgggggtggggtatttaaaaattaactcattag atcataaacgtcaaggattgattggaccaggcaaga gccatgtttttgagaaggttctggatctctgactccatcctgactgtttagtaagagcatgcttacaccctac tgtgaaaaggggaggggatgtggtaagcagaaacagaagacaggcagcagaggcattaaaaatgcataccatg ctttcagaacaaaagctctgggccagaaaggcaatttggctaaaaaatgaataagactacttctaatgtaact aagcatctccactatggtgtgtgccttttataaaggaaaagagagaaaaaggcaaagcaaggttgtggcctta ggttggacctggaatatcccttattgcctataatggaatatgtgacactgtgggtgaaatgttctacacacca cacactaggccattttcagatcagcagtcacccatcgcttagcatagaaatcccaaaacctccagcccgggaa cactataagcttcgaccattcaggaatctgccctgcactttgcatatctgtatagaaaatcaagtcaatcccc catcctcacacccactcatctctgaggagctatgaactggttttggtccctctaatgatcctccagcctcatc taatgccccccaaagactgatacaagtaacctcccctctgcttaggtgtcactttctcagcatatcaagttta ggcagcaagggaaaggaatatgggtcagttctcaaatgtcaatgtagataagagtcatctagtagagaactca tcagagtgcggattgccaagacccttctccagagattatggggttgggggtggaggtctagaggtgagctcag aaacctactgttaaccaacacccccaagtgactgacacaggtggtctaaaaattacttttctagaaacaccat tctggaagtttggctgcccacaggcaggaggagaagcatgaagagaaaacctgtttgagaagttttgttttgt tttgttttgctttttaataattttagcacacatctgctgactctccttcaacatcctcacccccatccctggg caccatttaggacaagacttccttatttatcaattacttgatttatcttctcaggactcattgttccaccccc aaccaatttgaatgcctacaataagttcaggagctgtgccaagcactttcctcttttacagctggagatcact ggaaaggtgtctcagtcacaaaacttctccctctactactggatgaaatgtctgcatttccaccaaaatctac ccagtcacccagggaataacaacttaagctgtagttagataacacctagtgattaattggctgagaaaaccct ggagtggagggaggctcagagatactgatatggatgtgggagggctctaaagttagaggtcaccaactccaca gatgaaacagttcaataatgaggaaacaggtgagccctgaaaacacaaaaggacagttctgtgttgaaacacc ccatcccctcacgttctcaccccaggcccagaagtaggttgcaactgcctttggaagattttgccccttagcc atccccacccacttgtaccagctaagaatgctggagactctgccaccatgctctgcgtgcccctgaacctctg tgcagcccggaaggctgatgtacaggtgtacctcaatccacattacagccatgctcctaatgtacatggacat ttttgtaactcagctcatattctgactgtatttgagaagctggctgtttaagggaacccagaagtgaattctt ttgtaaagtaaagcacccttttgtaatgcaattaat a cccttaatgtatctgttttgtaagtctgcatttt tgta atcgggtttaccttaagcttctctagtgaggcattctgagcagtggtgatcacatgccagatcgccct gcc atccacaaagtagatgaccaatgcacgctcctcaaacatctttggaggaactacctggccaaaacactg gccaggatgcagcaagcagcagcaggggctgacagcaggcttactgccatcaacattgcttgaaatgcc cta tgttctgaataaagaaaaaccataattgcttgtggtgaaacgaagcagtct ca gttaagtagcaatggt a tttttattggtagtaactgaacagtgttttgcaatttgtgaaacagtgtattgtgttttgtaaaatgatgtca tgaaatggtgggtccttggaaacctcctttccgttcagctctgcctctgttctttcaactcctttgaggctca aaaaaaacacaaagatcagaagccttcagatagagggtggtattctggtaaagaagaaagagataagggacgc tacct gcttttctggcacaggaagcacatgataaagcatgctcagaggagctggaacaga atagctacctg gttcgtgtaaataagaataatcaaggccccagagtgtgtatgcttccaggtggaggagaaaggggaatc ccc aaaatttaaaaacaaattggaagaataaccaggacagccaagtgaagcagccacagggacccaagcagtcgag gtctttaatgtgcctggagatgactctctge atteatgaatcttgctattgcacaaaccc a caagagctg ctgcttcccttccagccagaaaagtggtaagcggagcaagtgccaagcagaacagaccttatcatctgggtaa cagacttctcagtgttggtgc gtgtctgttagagccttagagcaagttaagcacttccttggtgtgggtaaa gaataaaggggaaagaaactactttagagcctctttttctcccaactcatatttttgataggaaaaacagaaa acccatccagttcttcagaaattgctttctaggcattaatactactt actatctatactgtttagttattcc tttctttacccacctaaactatccatctaatccaggattccctcactctttttttttagt actaatcatttt atgaaaataatgtatttataagtattttcttaaggtttgtgaagagtat tgcattgtgtcttcattttaatg tgtttgcaatcgctccgctccaggaagaacggaaatgctgtcttgtgagcatgaagtgaacgggctgttttgc tccagccacttttcttgtacaaccacatggatggattagatgtcctcaggtcttttccatcttcagtttctat gactgtggaataaatgttcagatagaaacttc [0323] Following is an PFTKl cDNA sequence (SEQ ID NO: 9). NM_012395 [gi:32130539] Homo sapiens PFTAIRE protein kinase 1 (PFTKl), mRNA gcatccccttgattaaatgtttttcctcctatgcaatcaccattagctgtttggctcccattctg attcttc tgaagcagccctgcattgcaaatcaa atctttctgaaaagacagtgtgttgtgaattgccttgacagcatat gcacggttactttggctgcaatgc gctgcagagcccggttac ctgccttcgtgggaactccacagatatgt gtcacaaagatgtctacacggaactgccagggaatggactcag ga caaacccctggacacaattcctgagg a aaaaaagtcagagttcagaggacacagagcacttttgacccatttgagaaaccagctaatcaagtaaagag ggtgcattctgagaacaatgcttgcattaactttaagacctcctccactggcaaagagtcacctaaagttagg cggcactccagccccagctcgccaacaagtcccaaatttggaaaagctgac catatgaaaagctggaaaaac taggggaaggatcttatgc acagtatacaaagggaaaagcaaggtaaatgggaagttggtagctctgaaggt gatcaggctgcaggaagaagaagggacacctttcacagc atcagggaagcttctcttttaaaaggactaaaa ca gctaacatagtgctacttcatgacatcatccataccaaggagacgctgacacttgtgtttgaatatgtgc acactga ttatgtcagtacatggacaagcaccctggggggctgcatccagataatgtgaagttgtttttatt tcagttgctgcgaggtctgtcttacatccaccagcgttatattttgcacagagacctgaaaccacagaacctt ctgatcagtgacacgggggagttaaagctggcagatttcggtcttgcaagagcaaaatccgtccctagccaca catactccaacgaagtggttaccttgtggtacagacctccagatgtccttctaggctcaacagaatattccac ctgccttgacatgtggggagtaggttgcatctttgttgaaatgatccaaggagttgctgcttttccaggaatg aaagacattcaggatcaacttgaacgaatatttctggttcttggaacaccaaatgaggacacatggcctggag ttcattctttaccacattttaagccagaacgctttaccctgtacagctctaaaaaccttagacaagcatggaa taagctcagctatgtgaaccatgcagaggacctggcctccaagctcctacaatgttccccaaagaacagactg tcggcacaggctgccttgagccacgagtattttagtgacctgccgccacggctatgggaactcaccgacatgt cttctatttttactgtcccaaatgtgagattgcaaccagaagctggagaaagcatgcgggcctttgggaaaaa caatagttatggcaaaagtcta caaacagcaagcactgacaagcagcacattctcaagagcacacaggatta agttgtcatcattctgggaagaaaaaaaaaacattaatgaagaggccaataatatgaagggaatcatggatca gttttctttcgctccctgtggtggatttcacttacaagaaaattgaagctggcaagaccctgttttctctgca atttatttaaaaccttgcacgcatttggataccttgtgatttccaagaactacgtgaagattaagctttgctt actgatacatggcatgtattcttttcagtcttttgtgtttgattttgtttgatttccctctgcagcacagcgt ctctgtaaaggtttttatgctttcaccagccatgtcttaaatacattaagacaacacatttggtgttcacact tcttcagtaatgtctgaacttgaaagccacagagtggcataaaacaatgtgtgttttctttgagagcagtgca cattttgcaaccactaggaaggaaattttctgctaaagcaaacccctgttctctgacttgacaacttggcccc ggactgtggggccccacctgttgcttaccttttgaggtaattttgcaaatgtggtttttttacttggaaataa ctgcacatttatatataggatattggactctgcttagcattttcaagccacatagcatgactgttttttgaat aggttggaattgaaaaaacaattatcaaacgttaagaacaaagacagggataaattgcttacatttcaacctc tagagattgaggtaactttttgtgtctgggtcttgtcaacatctaatttttttccatccattctgttacactt tgtattttctaactggagaaaagagtgaggaacagaatgttttaaatctggtgcaaaagaactatatctgctg gatgagccttgaaagcagtcttggcctgttagggcttacaaagtaaattacaaagtgatccagttcaaagttt gcttagttacaacaaagcacctttaaaaaaaatacattttaaaaaaacattccaagccaattggaagacatca ttgggttcttactttaagacatctcctggaataactgttcaaatgcaggttttagaaacaatgcaggaatctt gctttaaagatgaaaaagggaatgggccagcttccct actcaaggagttgagggaccttggaggatgaaggc gagtatgtgacactggagaaaagtggaccaggcatgtcttttgctttga ctggagggagggctgcctgatgc aggccggctcccagtggggcaggcctcgctgcagaatgcccagtag actgcggccaaggggacagttaggag acttcatctaaagcatgaaacctagctcctctacacacaaattcctatggaaatacctttgtgtacagtgtct tacattttcctattagtcagaaagaaggagagaatgagtgagtgcttgaaatgtgtca actgttttaggatc aagactaggaattaggagccaggttgacaaggactttttctgagagttgggtgagggtaaagcttttctataa tcaagctcaatacaccaaggaaactggatccagaattcctaaactttaaaatggtactgtctgcggagtggag atggatggttatgtcaaagtca agt catcc a ccagatgtagcat catggtaaacttttaagtgctaa gcaaggaattatttactgattggttttaaagagagcagaaaacacccaagtgtagaatgtctac gtttgcta cctagaaatcttttccattcctctttcatacattccaacccactggaagtctttagaggtattttgatttaaa gtatacttaaattaggatttcttaaagaaaacatagggagaaaactttacatgcaattaaaaatggactttcc tgtgatttgtttttaatcattcatttggagaagaggcatgacctttgtatttcactaagtttaaagcaagagc aactga gattaaatgttgct tttaataaggtttttaacttgaaaatttgaaaatatttaatgttgaaagac ttcaattagggctattagagttatatctccctgtcgtaggcagcttcttcggagaagtgaaata aacattac tcagtggacggagaagtctgttttgttacagagacatgcctctcagaaggtcaggaggttttgag ace ate cttgccacccatacaggaaatccaaagtttggtgtctctctctctctgtctctttctttctctttctcccccc aaacccctctcactccctccctccctctctccttcccctatttgcaatcata tctccctctgcttcttttct cttctgcctccttgtgggcagtca gaaaatcaattcagactgtgttcattagcagatttattattctattga gaaagcactggaatgttttgtgagatta ttttatatgaaggaatagcctgaactcaaacagatggtaagaat agtacaaacaccttagcacatcactgcacacacagta tctgaaaggagatttgacacttaattcccattttc ttaaaataacagttttgttgacttaaaaatatgagatacataggatgtgaaaaaaaatgtttgcagtac cag caaaaaatagggtacataaagcagggtggctgtccatccactgattctggggtgagaagcgatttctacctcg caagagtgactagaaagtttctaggagcacctccaggcttgcaaagaaagtgaggcctcttggta cctttcc tcagtgtgtatatgacagccagta aatcaataccctaggtta gcgtctata gatactcatctgtgaatat tattggttttgtaatctttgt atataagaggatgtttaggctgta atac ggggtagattat gcctgccc ct atacataggaatatgctgcataattgcgcataacttccatctccct ac ggcttgtaggcagaggaaac tg atatgttactgccttgtacttttctcatacaccaaaaacacaccaaaaaaatcaataaaataagcaatct tctattctcattccttttcccacagcagcatattttagaggcacatacaaaacctacattctctagttgggag tggatttttaaagttttccttttatcttttatttttttttgtatgatgcactgagatgtgtactttctaacag gggattggtacctaagaaatgtggtagcattattcagaaaactattatactttcaaatgacacatagtaagga gaatggaataatacatgttgcata ttgttaccagttgtaatttgtctgtattatgaaagatgtaatggtttg tcagctgtcactgttgttttcttgtaacatga atggaataaag atagcagaatctccgt [0324] Following is a SERPINA5 cDNA sequence (SEQ ID NO: 10).

NM_000624 [gi:34147643] Homo sapiens serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin) , member 5 (SERPINA5), mRNA ctcagctacgggacacatttcaggtatccaaggcagcagaggtgagtgggtcccccgagctctgtgaccttat gc ccacactaactctggcagagcctccgtttcctca agaacaaagaacagccaccatgcagctcttcctcc tcttgtgcctggtgcttctcagccctcagggggcctcccttcaccgccaccacccccgggagatgaagaagag agtcgaggacctccatgtaggtgccacggtggcccccagcagcagaagggactttacctttgacctctacagg gccttggcttccgctgcccccagccagaacatcttcttctcccctgtgagcatctccatgagcctggccatgc tctccctgggggctgggtccagcacaaagatgcagatcctggagggcctgggcctcaacctccagaaaagctc agagaaggagctgcacagaggctttcagcagctccttcaggaactcaaccagcccagagatggcttccagctg agcctcggcaatgcccttttcaccgacctggtggtagacctgcaggacaccttcgtaagtgccatgaagacgc tgtacctggcagacactttccccaccaactttagggactctgcaggggccatgaagcagatcaatgattatgt ggcaaagcaaacgaagggcaagattgtggacttgcttaagaacctcgatagcaatgcggtcgtgatcatggtg aattacatcttctttaaagctaagtgggagacaagcttcaaccacaaaggcacccaagagcaagacttctacg tgacctcggagactgtggtgcgggtacccatgatgagccgcgaggatcagtatcactacctcctggaccggaa cctctcctgcagggtggtgggggtcccctaccaaggcaatgccacggctttgttcattctccccagtgaggga aagatgcagcaggtggagaatggactgagtgagaaaacgctgaggaagtggcttaagatgttcaaaaagaggc agctcgagctttaccttcccaaattctccattgagggctcctatcagctggagaaagtcctccccagtctggg gatcagtaacgtcttcacctccca gctga ctgtccggcatcagcaaccactcaaatatccaggtgtctgag atggtgcacaaagctgtggtggaggtggacgagtcgggaaccagagcagcggcagccacggggacaatcttca ctttcaggtcggcccgcctgaactctcagaggctagtgttcaacaggccctttc gatgttcattgtggataa caacatcctcttccttggcaaagtgaaccgcccctgaggtggggcttctcctgaaatctacaggcctcagggt gggagatgaagggggcta gctatggcccatctgtatgctggtagctagtgatttacacaggtttagttgact aatgaggcattacaaataatat actctatgatgattgcttccacccacacgactgcaacatacaggtgcctt ggggaaatgtggagaacattcaatcttgccgtcactattcatcaatgaagattagcactgagatccagagagg ctggatgacttgctcaagttcaccagcatggtagtggcaaagagaggtccagagtcctggccct ga gccca gctcagtgccacaaagctcagtaggagggatgttccagtggatgagggccaccaggaagcacaggtccaaggc tggtcccacact atcagcagcaacaactgtcagttcatcctgcatgggaaaaatgttggaatgggagtctga aatggggctactgtttcagtcctaacgtgctgtgtgacattgggacaacactttccctctctggacctcagtt tccctctgta acaaggatcagattcttgctgtgacccaagaactcctgaaatcat tagaaaggctggggtg ggccctg ca tcgtggttgatttcaatacactcaagtgccattcatcctttaagaaaaacatctggatatca aggtggaaatggcccatttaatgattgattata ca tttgtggatatagt ataatctgatgggcctggctg ggagtggaagaagggaagccttttgcaaatagtagagtgtcagttgcaggtgccaatgactaactttttgaat tc atgttggcattaacaataaagcattttgcaaacaaaaaaaaaaaaaaaaaaa [0325] Followingis a LOCI 15209cDNA sequence (SEQ IDNO: 11).

NM_145243 [gi : 33186904] Homo sapiens metalloprotease related protein 1 (MPRP-1), mRNA. ggcacgagcgggcaggaagtgcgggtgcgcgcctgcgcataggtcgggtctgcggtgtcaccgctttcgcttc tgcttgagtaatcaagtgaaaaaatgagct catctgtggattgcagtctgctgctagaaaccatgttttctt ccgatttaattcactgtctaactggagaaaatgtaacacattagcatccacctcacggggctgtcatcaagta caagttaacca atagtaaataagtatcagggactgggagtaaatcagtgtgacaggtggagttttctgcctg gaaactttcatttttatagtacttttaacaacaaaagaacaggaggcctctcaagtaccaaaagtaaggaaat ttggaggattaccagcaaatg actgtatggaatgatgctttttcaagacagctgc aataaaagaagttaca gcagtccctagtctgtcagtattgcatcctctaagccctgcttccataagagctattaggaatttccatactt ctccacggtttcaagc gctccggttcctctcttgt ga ga tcttaaaccagtacagaagttatttgcaat cattgtaggcaggggcataaggaaatggtggcaggcacttcctcctaacaagaaggaagtagttaaagaaaat ataaggaagaataaatggaagctat ccttggtttgagtagttttggattgctctttgtggtgttt atttta ctcacctggaagtaagtccaatcacaggaaggagcaagc actattattggggaaagagcagttcagactttt atcggaactggaata gaagcatggatggaagaatttaaaaa gatatgctaactgagaaagatgcccgatac ctggctgttaaagaagtgctttg catctaattgaatgcaataaagatgttccagggatctctcagatcaatt gggt attcatgtggt gattccccaattattaatgccttcgtgcttccaaatggacaaatgtttgttttcac tggatttttaaatagtgtaaccgatattcatcaactttctttccttctgggccatgaaatagcacatgcag a cttgggcatgctgcagaaaaggctggcatggttcatttgttggatttcctaggtatgattttcctcacaatga tttgggccatttgtcctcgagatagcttggcacttttgtgccagtggatacagtctaaattgcaggagtatat gtttaatagaccatacagcagaaaattggaggccgaagctgacaaaattggactactgcttgctgcaaaggct tgtgcagacataagagccagttcagtgttttggcagcaaatggagttcgttgatagcctgcatggccaaccca agatgccagaatggttatctacacacccttctcatggcaatcgagttgagtacttggatagacttatacctca ggctctcaaaattagagagatgtgtaattgtccaccactgtctaatccagaccctcgattactattcaaactc agcacgaagcattttcttgaagaatcagagaaagaagacctaaatatcacgaagaaacagaaaatggatactc ttcctattcaaaaacaggagcaaataccattaacatacatagttgagaaaagaacgggcagttgaattaaaat ttatgagacacaagatatatgaagaatgttgcagtccttatcattttatgttactttttaaaaaatgatgttt gaagtgaaaaaaaaaaggatattcagggtcaaatcatgtacattacagatatta ctaaattcttctagaatt tatttttcatgaaatattgatgtattttaatctatgttaaaa atcttcaatgaggaaaatgtcacagaataa atttatattacacattttaaaaaaaaaaaaaaaaaaaa [0326] Following is a HRMT1L3 cDNA sequence (SEQ ID NO: 12).

NM_019854 [gi : 21314691] Homo sapiens HMT1 hnRNP methyltransferase-li e 3 (S. cerevisiae) ac gtctcggtatcaccaaacccttgcaggctcttatgggcatgaaacactcctcccgctgcctgctcctgag gaggaaaatggcggagaacgcggccgagagcaccgaggtgaacagccccccctcccagcccccccagcccgtc gtccc gctaagcccgtgcaatgcgtccatcatgtgtccactcaacccagctgcccaggacggggcaagatgt ccaagctgctgaacccagaggagatgacctcgagagattattacttcgactcctatgcccactttgggatcca cgaggaaatgctgaaggatgaggtgcggactctcacttaccggaactccatgtaccacaacaagcacgtgttc aaggacaaagtggtactggatgtggggagtggtactgggatcctttccatgttcgctgccaaggcaggggcca agaaggtgtttgggatcgaatgctccagtatttctgactactcacagaagatcattaaggccaaccacttgga caaca catcaccatatttaagggtaaagtggaagaggtggagctgcctgtggagaaggtggacatca catc agcgagtggatgggctactgtctgttctatgagtcca gctcaacacggtgatctttgccagggacaagtggc tgaaacctggagggcttatgtttccagaccgggcagctttgtacgtggtagcgattgaagacagacagtacaa ggacttcaaaatccactggtgggagaatgtctatggctttgacatgacctgcatcagggacgtggccatgaag gagcctctagtggacatcgtggatccaaagcaagtggtgaccaatgcctgtttgataaaggaggtggacattt acacagtgaagacggaagagctatcgttcacatctgcattctgcctgcagatacagcgcaacgactacgtcca cgccctggtcacctattttaatattgaatttaccaagtgccacaagaaaatggggttttccacagcccctgat gctccctacacccactggaagcagaccgtcttctacttggaagattacctcactgtccggaggggggaggaaa tctacgggaccatatccatgaagccaaatgccaaaaatgtgcgagacctcgatttcacagtagacttggattt taagggacagctgtgtgaaacatctgtatctaatgactacaaaatgcgttagcacacgtgggaagctgcagag agcaacgagaaaaggaactctcacctcgatctgccgtgccgtcccaaagaataccgtttgcaggactacacac ttgaaaaccagagttttcaactctgccttgaagattggtgaactccccagggctccagtgggctctgccactg gacagaaggcctccagctcctccgctctgccctggtagcccttcacgaaggctttgtgttgccaacaaagagc gacctggcgtgctgtggctgggccccgagggtggaaacgtattcgcgtctccccgtctcctccttaactgtga ctctccgggtcttctgagttttgcatgctgcgggtgtctaggacagattgcttccactagaacctggagacat agcatctttgatagcataagccagattatctgtgtgtgcggtggtgtgcgtgtgcgtgcatgtgtgaatgtga gcagcatagttgatatttacccacaaacacctgtatatgcgtgcata acaaccaagtgggtagacctaggtg ttctctcagaggggtgtgtgtgtgtgtgcgtgcgcgtgtgcctagaatatatattac ctcagaggagattct gttgc tttgaataggaatttgttttgtgattagttcgccccttccccaccccttaccagatgttaagcagct atgaaacattctctgtactagttctggtctccttttgactggactgtggctctgaaccttgagcatagtacca cggactccgtgggcgctcaataaacacacatgagaacaaaaaaaaaaaaaaaa [0327] Following are SPUVE, GRIN3A, PFTKl, SERPINA5, LOCI 15209 and HRMT1L3 amino acid sequences (SEQ ID NO: 13, 14, 15, 16, 17 and 18, respectively). [0328] Following is a SPUVE amino acid sequence (SEQ ID NO: 13) and a table showing domainregions therein.

NP_009104. [gi: 6005882] serine protease, umbilical endothelium [Homo sapiens] . AGIPGLLFLLFFLLCAVGQVSPYSAPWKPT PAYRLPVVLPQSTLNLAKPDFGAEAKLEVSSSCGPQCHKGT PLPTYEEAKQYLSYETLYANGSRTETQVGIYILSSSGDGAQHRDSGSSGKSRRKRQIYGYDSRFSIFGKDFLL NYPFSTSVKLSTGCTGTLVAEKHVLTAAHCIHDGKTYVKGTQK RVGFLKPKFKDGGRGANDSTSAMPEQMKF Q IRVKRTHVPKGWIKGNANDIGMDYDYALLEL KPHKRKFMKIGVSPPAKQLPGGRIHFSGYDNDRPGNLVY RFCDVKDETYDLLYQQCDAQPGASGSGVYVRM KRQQQKWERKIIGIFSGHQ VDMNGSPQDFNVAVRITPLK YAQICY IKGNYLDCREG ( 383 aa)

SPUVE DOMAINS

[0329] Following is a GRIN3A amino acid sequence (SEQ ID NO: 14) and a table showing domain regions therein.

NP_597702. [gi : 20143964] glutamate receptor, ionotropic, N-methyl-D- aspartate 3A [Homo sapiens] .

MRR SL WLLSRVCLLLPPPCALVAGVPSSSSHPQPCQILKRIGHAVRVGAVHLQPWTTAPRAASRAPDDSR AGAQRDEPEPGTRRSPAPSPGARWLGSTLHGRGPPGSRKPGEGARAEAL PRDALLFAVDNLNRVEGLLPYNL SLEVVMAIEAGLGDLP LPFSSPSSP SSDPFSFLQSVCHTVVVQGVSALLAFPQSQGEMMELDLVSLVLHIP VISIVRHEFPRESQNPLHLQLSLENSLSSDADVTVSILTMNNWYNFS LLCQED NITDFLLLTQNNSKFHLG SIINITANLPSTQDLLSFLQIQLESIKNSTPTVVMFGCDMESIRRIFEITTQFGVMPPELRWVLGDSQNVEEL RTEGLPLGLIAHGKTTQSVFEHYVQDAMELVARAVATATMIQPELALIPSTMNCMEVETTNLTSGQYLSRFLA NTTFRGLSGSIRVKGSTIVSSENNFFI NLQHDPMGKPMWTRLGS QGGKIVMDYGIWPEQAQRHKTHFQHPS KLHLRVVTLIEHPFVFTREVDDEGLCPAGQLCLDPMTNDSSTLDSLFSSLHSSNDTVPIKFKKCCYGYCIDLL EKIAEDMNFDFDLYIVGDGKYGAWKNGHWTGLVGDLLRGTAHMAVTSFSINTARSQVIDFTSPFFSTSLGILV RTRDTAAPIGAFMWP HWTMWLGIFVALHITAVFLTLYE KSPFGLTPKGRNRSKVFSFSSALNICYALLFGR TVAIKPPKC TGRFL NL AIFCMFCLSTYTANLAAVMVGEKIYEELSGIHDPKLHHPSQGFRFGTVRESSAE DYVRQSFPEMHEYMRRYNVPATPDGVEYLKNDPEKLDAFIMDKALLDYEVSIDADCKLLTVGKPFAIEGYGIG LPPNSPLTANISELISQYKSHGFMDMLHDKWYRVVPCGKRSFAVTETLQMGIKHFSGLFVLLCIGFGLSILTT IGEHIVYRLLLPRIKNKSKLQY LHTSQRLHRAINTSFIEEKQQHFKTKRVEKRSNVGPRQLTV NTSNLSHD NRRKYIFSDEEGQNQLGIQIHQDIPLPPRRRELPALRTTNG ADSLNVSRNSVMQELSELEKQIQVIRQELQL AVSRKTELEEYQRTSRTCES (1115 aa)

GRIN3A DOMAINS

[0330] Following is an PFTKl amino acid sequence (SEQ ID NO: 15) and a table showing domainregions therein.

NP_036527. [gi: 6912584] PFTAIRE protein kinase 1 [Homo sapiens]

MHGYFGCNAAAEPGYSAFVGTPQICVTKMSTRNCQGMDSVIKPLDTIPEDKKVRVQRTQSTFDPFEKPANQVK RVHSENNACINFKTSSTGKESPKVRRHSSPSSPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLVALK VIRLQEEEGTPFTAIREASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFL FQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEWTLWYRPPDVLLGSTEYS TCLDM GVGCIFVEMIQGVAAFPG KDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKNLRQA NKLSYVNHAEDLASKLLQCSPIOSIRLSAQAALSHEYFSDLPPRLWELTDMSSIFTVPNVRLQPEAGESMRAFGK NNSYGKSLSNSKH (451 aa)

PFTKl DOMAINS

[0331] Following is a SERPINA5 amino acid sequence (SEQ ID NO: 16) and a table showing domain regions therein.

NP_000615. [gi : 21361195] serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin) , member 5 [Homo sapiens]

MQLFLLLCLVLLSPQGASLHRHHPREMKKRVEDLHVGATVAPSSRRDFTFDLYRALASAAPSQNIFFSPVSIS MSLAMLSLGAGSSTK QILEGLGLNLQKSSEKELHRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFV SA KTLYLADTFPTNFRDSAGAMKQINDYVAKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAK ETSFNHKGTQ EQDFYVTSETVVRVPMMSREDQYHYLLDRNLSCRWGVPYQGNATALFILPSEGKMQQVENGLSEKTLRK LK MFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHAD SGISNHSNIQVSEMVHKAWEVDESGTRAAAA TGTIFTFRSARLNSQRLVFNRPFLMFIVDNNILFLGKVNRP (406 aa)

SERPINA5 DOMAINS

[0332] Following is a LOCI 15209 amino acid sequence (SEQ ID NO: 17) and a table showing domain regions therein.

NP_660286. [gi : 21686999] metalloprotease related protein 1 [Homo sapiens]

MSFICGLQSAARNHVFFRFNSLSN RKCNTLASTSRGCHQVQVNHIVNKYQGLGVNQCDRWSFLPGNFHFYST FNNKRTGGLSSTKSKEIWRITSKCTV NDAFSRQLLIKEVTAVPSLSVLHPLSPASIRAIRNFHTSPRFQAAP VPLLLMILKPVQ LFAIIVGRGIRK QALPPNKKEVVKENIRKNK KLFLGLSSFGLLFVVFYFTHLEVSPI TGRSKLLLLGKEQFRLLSELEYEAWMEEFKNDMLTEKDARYLAVKEVLCHLIECN DVPGISQIN VIHVVDS PIINAFVLPNGQMFVFTGFLNSVTDIHQ SFLLGHEIAHAVLGHAAE AGMVHLLDFLGMIFLTMI AICPRD SLALLCQWIQSKLQEYMFNRPYSRKLEAEADKIGLLLAAKACADIRASSVF QQMEFVDSLHGQPKMPE LST HPSHGNRVEYLDRLIPQALKIREMCNCPPLSNPDPRLLFKLSTKHFLEESEKEDLNIT QKMDTLPIQKQEQ IPLTYIVEKRTGS (524 aa)

LOC115209 DOMAINS

[0333] Following is a HRMT1L3 amino acid sequence (SEQ ID NO: 18) and a table showing domain regions therein.

NP_062828. [gi : 21314692] HMT1 hnRNP methyltransferase-like 3 [Homo sapiens] .

MSKLLNPEEMTSRDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKWLDVGSGTGILSMFAAKAG AKKVFGIECSSISDYSQKIIKANHLDNIITIFKGKVEEVELPVEKVDIIISE MGYCLFYESMLNTVIFARDK WLKPGGLMFPDRAALYVVAIEDRQYKDFKIH WENVYGFDMTCIRDVAMKEPLVDIVDPKQVVTNACLIKEVD IYTVKTEELSFTSAFCLQIQRNDYVHALVTYFNIEFTKCHKKMGFSTAPDAPYTHWKQTVFYLEDYLTVRRGE EIYGTISMKPNAKNVRDLDFTVDLDFKGQLCETSVSNDYKMR (334 aa)

HRMTIL3 DOMAINS

[0334] Modifications may be made to the foregoing without departing from the basic aspects ofthe invention. Although the invention has been described in substantial detail with reference to one or more specific embodiments, those of skill in the art will recognize that changes may be made to the embodiments specifically disclosed in this application, yet these modifications and improvements are within the scope and spirit ofthe invention, as set forth in the claims which follow. For example, polymorphic variants disclosed in a concurrently filed U.S. patent application having attorney docket no. 524592006920 may be applied to embodiments described herein. Also, citation ofthe above publications or documents is not intended as an admission that any ofthe foregoing is pertinent prior art, nor does it constitute any admission as to the contents or date of these publications or documents. Each patent, patent application, document and publication referenced herein is hereby incorporated by reference in its entirety.

Claims

What is claimed is: 1. A method for identifying a subject at risk of breast cancer, which comprises detecting the presence or absence of one or more polymoφhic variations associated with breast cancer in a nucleic acid sample from a subject, wherein the one or more polymorphic variations are detected in a nucleotide sequence selected from the group consisting of: (a) a nucleotide sequence in SEQ ID NO: 1-6; (b) a nucleotide sequence which encodes a polypeptide encoded by a nucleotide sequence in SEQ ID NO: 1-6; (c) a nucleotide sequence which encodes a polypeptide that is 90% or more identical to the a ino acid sequence encoded by a nucleotide sequence in SEQ ID NO: 1-6; (d) a fragment of a nucleotide sequence of (a), (b), or (c); whereby the presence ofthe polymoφhic variation is indicative ofthe subject being at risk of breast cancer.

2. The method of claim 1 , which further comprises obtaining the nucleic acid sample from the subject.

3. The method of claim 1 , wherein the one or more polymoφhic variations are detected at one or more positions selected from the group consisting of rs2512980, rs2433444, rs2512990, rs4128368, rs744292, rs744293, rsl807014, rs2512992, rs2433453, rsl939117, rs2433452, rs2433451, rs750789, rs754490, rs2015747, rsl939115, rs2000537, rs2000538, rsl939116, rs2186616, rs2186617, rs2508423, rsl939118, rs2105587, rs872619, rs3809048, rs2511882, rsl939110, rsl954769, rs3781614, position 53700 of SEQ ID NO: 1, position 54089 of SEQ ID NO: 1, rs2155080, rs2155081, rs3177411, rsl939111, rsl939112, rsl939113, rsl939114, rs2511880, rsl892892, rsl892893, rs3016252, rs2511881, rs2005192, rs2011913, rs2555537 and rs2845686.

4. The method of claim 1 , wherein the one or more polymoφhic variations are detected at one or more positions selected from the group consisting of rsl939115, rs2186617, rs2105587, rsl939110, rsl939114 and rs2511880.

5. The method of claim 1 , wherein the one or more polymoφhic variations are detected at one or more positions in a region spanning positions 62560 to 110963 in SEQ ID NO: 1.

6. The method of claim 1 , wherein the one or more polymoφhic variations are detected at one or more positions selected from the group consisting of rsl 885977, rs2273976, rsl983812, rs3824473, rs3739722, rs942139, position 32434 of SEQ ID NO: 2, rs3739723, rs3739725, rsl323433, rsl323432, rs729688, rs2181562, rs2181561, rsl570514, rs2417290, rsl004362, rsl407875, rs2031202, rsl407874, rsl016428, andrsl016429.

7. The method of claim 1 , wherein a polymoφhic variation is detected at rsl 323433.

8. The method of claim 1 , wherein the one or more polymoφhic variations are detected at one or more positions in a region spanning positions 47793 to 50410 in SEQ ID NO: 2.

9. The method of claim 1, wherein the one or more polymoφhic variations are detected at one or more positions selected from the group consisting of rs6465273, rs994511, rsl 858767, position 122804 in SEQ ID NO: 3, rsl079528, rsl079527, rsl557651, rsl016963, rs756741, rs756740, rsl557654, rsl005875, rsl005874, rs2374358, rs2213982, rs2888811, rs3802016, rs3802017, rs2213981, rs2188242, rs2213980, rs3802019, rs3802020, rs3802021, rs2188241, rs3808223, rs2040520, rs718313, rsl858809, rs3824036, rs3808226, rs3808227, rsl989791, rs3824037, rs3779554, rs2188240, rs2188239, rslll0457, rs3779556, rslll0456, rs3779558, rs3729626, rs721175, rs2040519, rs2040518, rs3808229, rs3808230, rs3808231, rs3824038, rsl858808, rsl858807, and position 259268 in SEQ ID NO: 3.

10. The method of claim 1 , wherein the one or more polymoφhic variations are detected at one or more positions selected from the group consisting of rs756740, rsl557654, rs2188242, rs2040520, rs3824036, rsl989791, rs721175 and position 259268 in SEQ ID NO: 3.

11. The method of claim 1 , wherein the one or more polymoφhic variations are detected at one or more positions in a region spanning positions 151896 to 259268 in SEQ ID NO: 3.

12. The method of claim 1 , wherein the one or more polymoφhic variations are detected at one or more positions selected from the group consisting of rs746386, rs744589, rs2180872, rs2093265, rs2180873, rs2896287, rs2402477, rs2402478, rs2402479, rs2092712, rsl243280, rs910348, rs910349, rs882732, rs882731, rs910352, rs910353, rs910354, rs3762123, rs879362, rs3762122, rs5508, rs2144077, rs2284656, rs941755, rs2093266, rsl005348, rs5510, rs5511, rs3827893, rs2068790, rs2070777, rs5512, rsl007149, rsl998243, rs910342, rsl004958, rs761536, rs2144075, rsl955652, rsl955653, rsl 885135, rsl955655, rsl955656, rsl475937, rsl475938, rsl983657, position 40863 in SEQ ID NO: 4, position 40899 in SEQ ID NO: A, rs2144076, rs8019792, rs8020223, rs8019810, rs2854946, rs885786, rs2747116, rs2747117, rs2854947, rs2069957, rs2069958, rs2069959, rs2854948, rs2069962, rs2069963, rs2069965, rs2069966, rs2069967, rs2069968, rs2069969, rs2069970, rs2069998, rs2069971, rs2069972, rs2069973, rs2069974, rs3177817, rs2069975, rs6113, rs6118, rs6115, rs2069976, rs2069999, rs6120, rs6112, rs2069977, rs2069978, rs2069979, rs2070004, rs2069982, rs2069983, rs2066969, rs2069984, rs6114, rs2069985, rs2069986, rs3177818, rs6107, rs2069987, rs2982746, rs2982747, rs2069988, rs2069989, rs6109, rs6116, rs2069990, rs6108, rs2070005, rs2067060, rs2069991, rs938, rsl050013, rs2069992, rs9113, rs2069993, rs7069, rs7070, rs2854941, rs2069994, rs2069995, rs2069996, rs2069997, rs2854942, rs2747118, rs2854943, rs2854944, rsl 884077, rsl884078, rsl884079, rsl884081, rs742894, rs742895, rs2402480, rs2402481, position 56372 in SEQ ID NO: 4, rsl 1160194, rs8009357, rs734475, rs957620, rs926788, rs926790, rsl955658, rsl004761, rsl884082, rs4934, rs2896288, rs2268334, rs2268335, rs2268336, rs2268337, rsl7473, rs742896, rs2402482, rs733815, rs910350, rs2284657, rs2284658, rs742897, rsl065623, rs3180112, rs742898, rsl l57271, rsl950298, rsl955659, rsll54824, rsll54825, rs979048, rsl 950300, rs997280 and rs990777.

13. The method of claim 1 , wherein the one or more polymoφhic variations are detected at one or more positions selected from the group consisting of rs2069990, rs2854943, rsl004761 and rs2268335.

14. The method of claim 1 , wherein the one or more polymoφhic variations are detected at one or more positions in a region spanning positions 23143 to 75716 in SEQ ID NO: 4.

15. The method of claim 1 , wherein the one or more polymoφhic variations are detected at one or more positions selected from the group consisting of rs706460, rs706461, rs697587, rs706462, rs706463, rs644319, rs642657, rs706464, rs630638, rs338254, rs338253, rs338252, rs338251, rs697588, rs338250, rs338249, rs338248, rs697589, rs338247, rs696297, rs697590, rs338245, rs338243, rs822064, rs338242, rs338241, rs338240, rs338239, rs338238, rs822061, rs697592, rs338237, rs338235, rs338234, rs338232, rs338231, rs2153731, rs338230, rs338229, rs338228, position 24422 of SEQ ID NO: 5, rs697593, rs338225, rs338226, rs338227, rsl93133, rsl84617, rsl93134, rs618043, rs618932, rs697594, rs697595, rsl228818, rsl503646, rsl983078, rs2062833, rsl394000, rs2271004, rs2271005, rsl503648, rsl847351, rsl388981, rsl388980, position 77510 of SEQ ID NO: 5, position 82668 of SEQ ID NO: 5, rs902925, position 83005 of SEQ ID NO: 5, position 83031 of SEQ ID NO: 5, rs2406786, rs3813996, rs905567, rs2087799, rs2406785, rs2406784, rs4316384, rs4399185, rs2406783, rsl799705, rsl775002, rs644928, rs488606, rs530095, rs593279, rs532134, rs564252, rs565008, rs565954, rs567787, rs673276, rs672859, rs671830, rs511687, rs518070, rsl627332, rs542727, rs544596, rs627218, rs627633 and and rs546271.

16. The method of claim 1 , wherein the one or more polymoφhic variations are detected at one or more positions selected from the group consisting of rs338228, rs338225, rs2271005, rsl847351, position 77510 of SEQ ID NO: 5, position 83031 of SEQ ID NO: 5, rs3813996, rs905567, rs2406785, rs2406784, rsl775002, rs565954, rs671830 and rs518070.

17. The method of claim 1 , wherein the one or more polymoφhic variations are detected at one or more positions in a region spanning positions 14202 to 99855 in SEQ ID NO: 5.

18. The method of claim 1 , wherein the one or more polymoφhic variations are detected at one or more positions selected from the group consisting of rs2878580, rs2335988, rs2335990, position 4012 of SEQ ID NO: 6, position 4154 of SEQ ID NO: 6, rs731577, rs2191204, rs3741939, rs3741938, rs3759362, rs3782761, rs3782760, rs3782759, rs3782758, rs3782756, rs2191205, rs3741937, rs3782755, rs878771, rs876593, rs3825340, position 39171 of SEQ ID NO: 6, position 39526 of SEQ ID NO: 6, rs3782753, rs3782752, rs2191216, rs3782751, rs3782750, rs3782749, rs3782748, rsl860450, rsl860449, rs3782747, rs3825339, rs3741936, rs917602, rs917601, rs917600, rs2191215, rs3782746, rs3782745, rs3782744, rsl860451, rs758637, rs917564, rs3741935, rsl029766, and rs887303.

19. The method of claim 1 , wherein the one or more polymoφhic variations are detected at one or more positions selected from the group consisting of position 4154 of SEQ ID NO: 6, rs2191216, rs917602 and rs917564.

20. The method of claim 1 , wherein the one or more polymoφhic variations are detected at one or more positions in a region spanning positions 4154 to 80061 in SEQ ID NO: 6.

21. The method of claim 1 , wherein the one or more polymoφhic variations are detected at one or more positions in linkage disequilibrium with one or more positions in claim 3, 4, 6, 7, 9, 10, 12, 13, 15, 16, 18 or 19.

22. The method of claim 1 , wherein detecting the presence or absence ofthe one or more polymoφhic variations comprises: hybridizing an oligonucleotide to the nucleic acid sample, wherein the oligonucleotide is complementary to a nucleotide sequence in the nucleic acid and hybridizes to a region adjacent to the polymoφhic variation; extending the oligonucleotide in the presence of one or more nucleotides, yielding extension products; and detecting the presence or absence of a polymoφhic variation in the extension products.

23. The method of claim 1 , wherein the subj ect is a human.

24. A method for identifying a polymoφhic variation associated with breast cancer proximal to an incident polymoφhic variation associated with breast cancer, which comprises: identifying a polymoφhic variation proximal to the incident polymoφhic variation associated with breast cancer, wherein the polymoφhic variation is detected in a nucleotide sequence selected from the group consisting of: (a) a nucleotide sequence in SEQ ID NO: 1 -6; (b) a nucleotide sequence which encodes a polypeptide encoded by a nucleotide sequence in SEQ ID NO: 1-6; (c) a nucleotide sequence which encodes a polypeptide that is 90% or more identical to the amino acid sequence encoded by a nucleotide sequence in SEQ ID NO: 1-6; (d) a fragment of a nucleotide sequence of (a), (b), or (c) comprising the polymoφhic variation; determining the presence or absence of an association ofthe proximal polymoφhic variant with breast cancer.

25. The method of claim 24, wherein the incident polymoφhic variation is at a position in claim 3, 4, 6, 7, 9, 10, 12, 13, 15, 16, 18 or 19.

26. The method of claim 24, wherein the proximal polymoφhic variation is within a region between about 5 kb 5' ofthe incident polymoφhic variation and about 5 kb 3' ofthe incident polymoφhic variation.

27. The method of claim 24, which further comprises determining whether the proximal polymoφhic variation is in linkage disequihbrium with the incident polymoφhic variation.

28. The method of claim 24, which further comprises identifying a second polymoφhic variation proximal to the identified proximal polymoφhic variation associated with breast cancer and deteπnining if the second proximal polymoφhic variation is associated with breast cancer.

29. The method of claim 28, wherein the second proximal polymoφhic variant is within a region between about 5 kb 5' ofthe incident polymoφhic variation and about 5 kb 3 ' of the proximal polymoφhic variation associated with breast cancer.

30. A method for identifying a candidate molecule that modulates cell proliferation, which comprises: (a) introducing a test molecule to a system which comprises a nucleic acid comprising a nucleotide sequence selected from the group consisting of: (i) a nucleotide sequence in SEQ ID NO: 1-6; (ii) a nucleotide sequence which encodes a polypeptide encoded by a nucleotide sequence in SEQ ID NO: 1-6; (iii) a nucleotide sequence which encodes a polypeptide that is 90% or more identical to the amino acid sequence encoded by a nucleotide sequence in SEQ ID NO: 1-6; (iv) a fragment of a nucleotide sequence of (i), (ii), or (iii); or introducing a test molecule to a system which comprises a protein encoded by a nucleotide sequence of (i), (ii), (iii), or (iv); and (b) determining the presence or absence of an interaction between the test molecule and the nucleic acid or protein, whereby the presence of an interaction between the test molecule and the nucleic acid or protein identifies the test molecule as a candidate molecule that modulates cell proliferation.

31. The method of claim 30, wherein the system is an animal.

32. The method of claim 30, wherein the system is a cell.

33. The method of claim 30, wherein the nucleotide sequence comprises one or more polymoφhic variations associated with breast cancer.

34. The method of claim 30, wherein the one or more polymoφhic variations associated with breast cancer are at one or more positions in claim 3, 4, 6, 1, 9, 10, 12, 13, 15, 16, 18 or 19.

35. A method for treating breast cancer in a subject, which comprises administering a candidate molecule identified by the method of claim 30 to a subject in need thereof, whereby the candidate molecule treats breast cancer in the subject.

36. A method for identifying a candidate therapeutic for treating breast cancer, which comprises: (a) introducing a test molecule to a system which comprises a nucleic acid comprising a nucleotide sequence selected from the group consisting of: (i) a nucleotide sequence in SEQ ID NO: 1-6; (ii) a nucleotide sequence which encodes a polypeptide encoded by a nucleotide sequence in SEQ ID NO: 1-6; (iii) a nucleotide sequence which encodes a polypeptide that is 90% or more identical to the amino acid sequence encoded by a nucleotide sequence in SEQ ID NO: 1-6; (iv) a fragment of a nucleotide sequence of (i), (ii), or (iii); or introducing a test molecule to a system which comprises a protein encoded by a nucleotide sequence of (i), (ii), (iii), or (iv); and (b) determining the presence or absence of an interaction between the test molecule and the nucleic acid or protein, whereby the presence of an interaction between the test molecule and the nucleic acid or protein identifies the test molecule as a candidate therapeutic for treating breast cancer.

37. The method of claim 36, wherein the test molecule inhibits cell proliferation or cell metastasis.

38. A method for treating breast cancer in a subject, which comprises contacting one or more cells of a subject in need thereof with a nucleic acid, wherein the nucleic acid comprises a nucleotide sequence selected from the group consisting of: (a) a nucleotide sequence in SEQ ID NO: 1-6; (b) a nucleotide sequence which encodes a polypeptide encoded by a nucleotide sequence in SEQ ID NO: 1-6; (c) a nucleotide sequence which encodes a polypeptide that is 90% or more identical to the amino acid sequence encoded by a nucleotide sequence in SEQ ID NO: 1-6; (d) a fragment of a nucleotide sequence of (a), (b), or (c); and (e) a nucleotide sequence complementary to the nucleotide sequences of (a), (b), (c), or (d); whereby contacting the one or more cells ofthe subject with the nucleic acid treats breast cancer in the subject.

39. The method of claim 38, wherein the nucleic acid is RNA or PNA.

40. The method of claim 39, wherein the nucleic acid is duplex RNA.

41. The method of claim 40, wherein a strand of the RNA comprises a nucleotide sequence selected from the group consisting of GAGGCCAAGCAATATCTGT (SEQ ID NO: ); GCGGCAGATTTATGGCTAT (SEQ ID NO: ); AAGACGAGACCTATGACTT (SEQ ID NO: ); ACGTGGCTGTCAGAATCAC (SEQ ID NO: ); GAGUUGGAUAGCAAGACAA (SEQ ID NO: ); CGUACGCGGAAUACUUCGA (SEQ ID NO: ); GTTCCACCTTGGTTCTATC (SEQ ID NO: ); ACATCCAAGTAAGCTACAC (SEQ ID NO: ); CGGAGCCAGGTGATAGATT (SEQ ID NO: ); GCATTTCAAGACCAAACGT (SEQ ID NO: ); GAGUUGGAUAGCAAGACAA (SEQ ID NO: ); CGUACGCGGAAUACUUCGA (SEQ ID NO: ); ACGAAGTGGTTACCTTGTG (SEQ ID NO: ); GACATTCAGGATCAACTTG (SEQ ID NO: ); GACAAGCATGGAATAAGCT (SEQ ID NO: ); GAGUUGGAUAGCAAGACAA (SEQ ID NO: ); CGUACGCGGAAUACUUCGA (SEQ ID NO: ); CUUUACCUUUGACCUCUAC (SEQ ID NO: ); AUGCGGUCGUGAUCAUGGU (SEQ ID NO: ); GAGUUGGAUAGCAAGACAA (SEQ ID NO: ); CGUACGCGGAAUACUUCGA (SEQ ID NO: ); AUCAGUGUGACAGGUGGAG (SEQ ID NO: ); GCCCUGCUUCCAUAAGAGC (SEQ ID NO: ); GAUGCCCGAUACCUGGCUG (SEQ ID NO: );

GAUGCCAGAAUGGUUAUCU (SEQ ID NO: ); GAGUUGGAUAGCAAGACAA (SEQ ID NO: ); CGUACGCGGAAUACUUCGA (SEQ ID NO: ); CAGACAGUACAAGGACUUC (SEQ ID NO: ); AGACGGAAGAGCUAUCGUU (SEQ ID NO: ); GAGUUGGAUAGCAAGACAA (SEQ ID NO: ) and CGUACGCGGAAUACUUCGA (SEQ ID NO: ).

42. A method for treating breast cancer in a subject, which comprises: detecting the presence or absence of one or more polymoφhic variations associated with breast cancer in a nucleic acid sample from a subject, wherein the one or more polymoφhic variation are detected in a nucleotide sequence selected from the group consisting of: (a) a nucleotide sequence in SEQ ID NO: 1-6; (b) a nucleotide sequence which encodes a polypeptide encoded by a nucleotide sequence in SEQ ID NO: 1-6; (c) a nucleotide sequence which encodes a polypeptide that is 90% or more identical to the amino acid sequence encoded by a nucleotide sequence in SEQ ID NO: 1-6; (d) a fragment of a nucleotide sequence of (a), (b), or (c) comprising the polymoφhic variation; and administering a breast cancer treatment to a subject in need thereof based upon the presence or absence ofthe one or more polymoφhic variations in the nucleic acid sample.

43. The method of claim 42, wherein the one or more polymoφhic variations are detected at one or more positions in claim 3, 4, 6, 7, 9, 10, 12, 13, 15, 16, 18 or 19. .

44. The method of claim 42, wherein the breast cancer treatment comprises a nucleic acid comprising a nucleotide sequence complementary to a nucleotide sequence in SEQ ID NO: 1-6 or a substantially identical nucleotide sequence thereof.

45. The method of claim 44, wherein the nucleic acid is a double stranded RNA.

46. The method of claim 45, wherein a strand ofthe RNA comprises a nucleotide sequence selected from the group consisting of GAGGCCAAGCAATATCTGT (SEQ ID NO: ); GCGGCAGATTTATGGCTAT (SEQ ID NO: ); AAGACGAGACCTATGACTT (SEQ ID NO: ); ACGTGGCTGTCAGAATCAC (SEQ ID NO: ); GAGUUGGAUAGCAAGACAA (SEQ ID NO: ); CGUACGCGGAAUACUUCGA (SEQ ID NO: ); GTTCCACCTTGGTTCTATC (SEQ ID NO: ); ACATCCAAGTAAGCTACAC (SEQ ID NO: ); CGGAGCCAGGTGATAGATT (SEQ ID NO: ); GCATTTCAAGACCAAACGT (SEQ ID NO: ); GAGUUGGAUAGCAAGACAA (SEQ ID NO: ); CGUACGCGGAAUACUUCGA (SEQ ID NO: ); ACGAAGTGGTTACCTTGTG (SEQ ID NO: ); GACATTCAGGATCAACTTG (SEQ ID NO: ); GACAAGCATGGAATAAGCT (SEQ ID NO: ); GAGUUGGAUAGCAAGACAA (SEQ ID NO: ); CGUACGCGGAAUACUUCGA (SEQ ID NO: ); CUUUACCUUUGACCUCUAC (SEQ ID NO: ); AUGCGGUCGUGAUCAUGGU (SEQ ID NO: ); GAGUUGGAUAGCAAGACAA (SEQ ID NO: ); CGUACGCGGAAUACUUCGA (SEQ ID NO: ); AUCAGUGUGACAGGUGGAG (SEQ ID NO: ); GCCCUGCUUCCAUAAGAGC (SEQ ID NO: ); GAUGCCCGAUACCUGGCUG (SEQ ID NO: );

47. The method of claim 42, which further comprises extracting and analyzing a tissue sample from the subject.

48. The method of claim 42, wherein the treatment is chemotherapy, surgery, radiation therapy, and combinations ofthe foregoing.

49. The method of claim 48, wherein the chemotherapy is selected from the group consisting of cyclophosphamide (Cytoxan), methotrexate (Amethopterin, Mexate, Folex), fluorouracil (Fluorouracil, 5-Fu, Adrucil), cyclophosphamide, doxorubicin (Adriamycin), and combinations ofthe foregoing.

50. The method of claim 49, wherein the combinations are selected from the group consisting of cyclophosphamide (Cytoxan), methotrexate (Amethopterin, Mexate, Folex), and fluorouracil (Fluorouracil, 5-Fu, Adrucil); cyclophosphamide, doxorubicin (Adriamycin), and fluorouracil; and doxorubicin and cyclophosphamide.

51. The method of claim 42, wherein the breast cancer treatment reduces breast cancer metastasis.

52. A method for detecting or preventing breast cancer in a subject, which comprises: detecting the presence or absence of one or more polymoφhic variations associated with breast cancer in a nucleic acid sample from a subject, wherein the polymoφhic variation is detected in a nucleotide sequence selected from the group consisting of: (a) a nucleotide sequence in SEQ ID NO: 1-6; (b) a nucleotide sequence which encodes a polypeptide encoded by a nucleotide sequence in SEQ ID NO: 1-6; (c) a nucleotide sequence which encodes a polypeptide that is 90% or more identical to the amino acid sequence encoded by a nucleotide sequence in SEQ ID NO: 1-6; (d) a fragment of a nucleotide sequence of (a), (b), or (c) comprising the polymoφhic variation; and administering a breast cancer prevention procedure or detection procedure to a subject in need thereof based upon the presence or absence ofthe one or more polymoφhic variations in the nucleic acid sample.

53. The method of claim 52, wherein the one or more polymoφhic variations are detected at one or more positions in wherein the one or more polymoφhic variations are detected at one or more positions in claim 3, 4, 6, 7, 9, 10, 12, 13, 15, 16, 18 or 19.

54. The method of claim 52, wherein the breast cancer detection procedure is selected from the group consisting of a mammography, an early mammography program, a frequent mammography program, a biopsy procedure, a breast biopsy and biopsy from another tissue, a breast ultrasound and optionally ultrasound analysis of another tissue, breast magnetic resonance imaging (MRI) and optionally MRI analysis of another tissue, electrical impedance (T-scan) analysis of breast and optionally of another tissue, ductal lavage, nuclear medicine analysis (e.g., scintimammography), BRCA1 and/or BRCA2 sequence analysis results, thermal imaging ofthe breast and optionally of another tissue, and a combination ofthe foregoing.

55. The method of claim 52, wherein the breast cancer prevention procedure is selected from the group consisting of one or more selective hormone receptor modulators, one or more compositions that prevent production of hormones, one or more hormonal treatments, one or more biologic response modifiers, surgery, and drugs that delay or halt metastasis.

56. The method of claim 55, wherein the selective hormone receptor modulator is selected from the group consisting of tamoxifen, reloxifene, and toremifene; the composition that prevents production of hormones is an aramotase inhibitor selected from the group consisting of exemestane, letrozole, anastrozol, groserelin, and megestrol; the hormonal treatment is selected from the group consisting of goserelin acetate and fulvestrant; the biologic response modifier is an antibody that specifically binds herceptin/HER2; the surgery is selected from the group consisting of lumpectomy and mastectomy; and the drug that delays or halts metastasis is pamidronate disodium.

57. A method of targeting hiformation for preventing or treating breast cancer to a subject in need thereof, which comprises: detecting the presence or absence of one, or more polymoφhic variations associated with breast cancer in a nucleic acid sample from a subject, wherein the polymoφhic variation is detected in a nucleotide sequence selected from the group consisting of: (a) a nucleotide sequence in SEQ ID NO: 1-6; (b) a nucleotide sequence which encodes a polypeptide encoded by a nucleotide sequence in SEQ ID NO: 1-6; (c) a nucleotide sequence which encodes a polypeptide that is 90% or more identical to the amino acid sequence encoded by a nucleotide sequence in SEQ ID NO: 1-6; (d) a fragment of a nucleotide sequence of (a), (b), or (c) comprising the polymoφhic variation; and directing information for preventing or treating breast cancer to a subject in need thereof based upon the presence or absence ofthe one or more polymoφhic variations in the nucleic acid sample.

58. The method of claim 57, wherein the one or more polymoφhic variations are detected at one or more positions in wherein the one or more polymoφhic variations are detected at one or more positions in claim 3, 4, 6, 7, 9, 10, 12, 13, 15, 16, 18 or 19.

59. The method of claim 57, wherein the information comprises a description of a breast cancer detection procedure, a chemotherapeutic treatment, a surgical treatment, a radiation treatment, a preventative treatment of breast cancer, or combinations ofthe foregoing.

60. A method of selecting a subject that will respond to a treatment of breast cancer, which comprises: detecting the presence or absence of one or more polymoφhic variations associated with breast cancer in a nucleic acid sample from a subject, wherein the polymoφhic variation is detected in a nucleotide sequence selected from the group consisting of: (a) the nucleotide sequence of SEQ ID NO: 1 -6; (b) a nucleotide sequence which encodes a polypeptide consisting of an amino acid sequence encoded by a nucleotide sequence in SEQ ID NO: 1-6 ; (c) a nucleotide sequence which encodes a polypeptide that is 90% or more identical to an amino acid sequence encoded by a nucleotide sequence in SEQ ID NO: 1-6 ; and (d) a fragment of a nucleotide sequence of (a), (b), or (c) comprising the polymoφhic variation; and selecting a subject that will respond to the breast cancer treatment based upon the presence or absence ofthe one or more polymoφhic variations in the nucleic acid sample.

61. The method of claim 60, wherein the one or more polymoφhic variations are at one or more positions in wherein the one or more polymoφhic variations are detected at one or more positions in claim 3, 4, 6, 7, 9, 10, 12, 13, 15, 16, 18 or 19.

62. A composition comprising a breast cancer cell and an antibody that specifically binds to a protein, polypeptide or peptide encoded by a nucleotide sequence identical to or 90% or more identical to a nucleotide sequence in SEQ ID NO: 1-12.

63. The composition of claim 62, wherein the antibody specifically binds to an epitope that comprises a lysine corresponding to an amino acid at position 105 in SEQ ID NO: 16, an isoleucine corresponding to an amino acid at position 329 in SEQ ID NO: 17, a histidine at a position corresponding to the amino acid at position 36 in SEQ ID NO: 13 or a serine at a position corresponding to the amino acid at position 166 in SEQ ID NO: 13.

64. A composition comprising a breast cancer cell and a RNA, DNA, PNA or ribozyme molecule comprising a nucleotide sequence identical to or 90% or more identical to a portion of a nucleotide sequence in SEQ ID NO: 1-12.

65. The composition of claim 64, wherein the RNA molecule is a short inhibitory RNA molecule.