EP1737357A4 - Transdermal delivery device - Google Patents

Transdermal delivery device

Info

Publication number
EP1737357A4
EP1737357A4 EP05732787A EP05732787A EP1737357A4 EP 1737357 A4 EP1737357 A4 EP 1737357A4 EP 05732787 A EP05732787 A EP 05732787A EP 05732787 A EP05732787 A EP 05732787A EP 1737357 A4 EP1737357 A4 EP 1737357A4
Authority
EP
European Patent Office
Prior art keywords
delivery device
transdermal delivery
transdermal
delivery
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP05732787A
Other languages
German (de)
French (fr)
Other versions
EP1737357B1 (en
EP1737357A2 (en
Inventor
Gary W Cleary
Steven R Klemm
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Corium LLC
Original Assignee
Corium International Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Corium International Inc filed Critical Corium International Inc
Publication of EP1737357A2 publication Critical patent/EP1737357A2/en
Publication of EP1737357A4 publication Critical patent/EP1737357A4/en
Application granted granted Critical
Publication of EP1737357B1 publication Critical patent/EP1737357B1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/20Surgical instruments, devices or methods, e.g. tourniquets for vaccinating or cleaning the skin previous to the vaccination
    • A61B17/205Vaccinating by means of needles or other puncturing devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023Drug applicators using microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Medicinal Preparation (AREA)
EP05732787.6A 2004-03-24 2005-03-24 Transdermal delivery device Active EP1737357B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US55584104P 2004-03-24 2004-03-24
PCT/US2005/009854 WO2005094526A2 (en) 2004-03-24 2005-03-24 Transdermal delivery device

Publications (3)

Publication Number Publication Date
EP1737357A2 EP1737357A2 (en) 2007-01-03
EP1737357A4 true EP1737357A4 (en) 2012-07-11
EP1737357B1 EP1737357B1 (en) 2019-12-11

Family

ID=35064415

Family Applications (1)

Application Number Title Priority Date Filing Date
EP05732787.6A Active EP1737357B1 (en) 2004-03-24 2005-03-24 Transdermal delivery device

Country Status (6)

Country Link
US (2) US7611481B2 (en)
EP (1) EP1737357B1 (en)
JP (1) JP5085317B2 (en)
AU (1) AU2005228145B2 (en)
CA (1) CA2560840C (en)
WO (1) WO2005094526A2 (en)

Families Citing this family (140)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010041869A1 (en) * 2000-03-23 2001-11-15 Causey James D. Control tabs for infusion devices and methods of using the same
US9717451B2 (en) 2000-06-08 2017-08-01 Becton, Dickinson And Company Device for withdrawing or administering a substance and method of manufacturing a device
US6607513B1 (en) * 2000-06-08 2003-08-19 Becton, Dickinson And Company Device for withdrawing or administering a substance and method of manufacturing a device
US7828827B2 (en) 2002-05-24 2010-11-09 Corium International, Inc. Method of exfoliation of skin using closely-packed microstructures
AU2005228145B2 (en) * 2004-03-24 2011-03-03 Corium Pharma Solutions, Inc. Transdermal delivery device
US7316665B2 (en) * 2004-08-25 2008-01-08 Becton, Dickinson And Company Method and device for the delivery of a substance including a covering
US8108023B2 (en) 2005-04-11 2012-01-31 Infotonics Technology Center, Inc. Blood monitoring systems and methods thereof
US20080009802A1 (en) * 2005-04-25 2008-01-10 Danilo Lambino Method of treating acne with stratum corneum piercing device
US20060253078A1 (en) * 2005-04-25 2006-11-09 Wu Jeffrey M Method of treating skin disorders with stratum corneum piercing device
US20070270738A1 (en) * 2005-04-25 2007-11-22 Wu Jeffrey M Method of treating ACNE with stratum corneum piercing patch
US8708982B2 (en) * 2005-05-04 2014-04-29 Edward D. Lin Wound protection and therapy system
WO2006130826A1 (en) * 2005-06-02 2006-12-07 Alza Corporation Method for terminal sterilization of transdermal delivery devices
AU2006261899B2 (en) 2005-06-27 2012-05-10 Kindeva Drug Delivery L.P. Microneedle cartridge assembly and method of applying
JP5137841B2 (en) 2005-10-13 2013-02-06 シンセス ゲーエムベーハー Drug impregnation container
CA2642182A1 (en) * 2006-02-17 2007-08-30 Zogenix, Inc. Method and system for delivery of neurotoxins
WO2008008557A1 (en) * 2006-07-11 2008-01-17 Infotonics Technology Center, Inc. Allergy testing cartridge with coated allergens
EP1925259B1 (en) * 2006-11-22 2012-01-18 Johnson and Johnson Consumer Companies, Inc. Skin-piercing device for treatment of acne
EP2121111B1 (en) 2007-01-22 2018-03-14 Corium International, Inc. Applicators for microneedle arrays
US9114238B2 (en) 2007-04-16 2015-08-25 Corium International, Inc. Solvent-cast microprotrusion arrays containing active ingredient
US8439861B2 (en) * 2007-04-24 2013-05-14 Velcro Industries B.V. Skin penetrating touch fasteners
DE102007025973A1 (en) * 2007-06-04 2008-12-11 Lts Lohmann Therapie-Systeme Ag Storage stable laminate sections
US8328720B2 (en) * 2007-08-10 2012-12-11 Infotonics Technology Center, Inc. MEMS interstitial prothrombin time test
WO2009048607A1 (en) 2007-10-10 2009-04-16 Corium International, Inc. Vaccine delivery via microneedle arrays
BRPI0906095A2 (en) 2008-03-05 2016-06-21 Kci Licensing Inc reduced pressure dressing to apply a reduced pressure treatment to a tissue site, method for collecting fluid in a bandage positioned at a tissue site and a reduced pressure dressing adapted to deliver a reduced pressure to a tissue site.
US8021347B2 (en) 2008-07-21 2011-09-20 Tyco Healthcare Group Lp Thin film wound dressing
US8298200B2 (en) 2009-06-01 2012-10-30 Tyco Healthcare Group Lp System for providing continual drainage in negative pressure wound therapy
US8700122B2 (en) 2008-05-02 2014-04-15 Covidien Lp Skin preparation device and biopotential sensor
US7883487B2 (en) * 2008-06-16 2011-02-08 Shantha Totada R Transdermal local anesthetic patch with injection port
WO2009158032A1 (en) 2008-06-25 2009-12-30 Fe2, Inc. Patches and methods for the transdermal delivery of a therapeutically effective amount of iron
US8404255B2 (en) * 2008-07-29 2013-03-26 Matt Gibson System and method for transdermal drug delivery
US8632497B2 (en) * 2008-10-09 2014-01-21 Roche Diagnostics Operations Inc. Skin securable drug delivery device with a shock absorbing protective shield
WO2010093472A2 (en) * 2009-02-12 2010-08-19 Incube Labs, Llc Method and apparatus for oscillatory iontophoretic transdermal delivery of a therapeutic agent
US8190252B2 (en) 2009-02-12 2012-05-29 Incube Labs, Llc Iontophoretic system for transdermal delivery of active agents for therapeutic and medicinal purposes
US8961492B2 (en) 2009-02-12 2015-02-24 Incube Labs, Llc System and method for controlling the iontophoretic delivery of therapeutic agents based on user inhalation
WO2010124255A2 (en) * 2009-04-24 2010-10-28 Corium International, Inc. Methods for manufacturing microprojection arrays
US8821945B2 (en) * 2009-04-25 2014-09-02 Fe3 Medical, Inc. Method for transdermal iontophoretic delivery of chelated agents
US20100286600A1 (en) * 2009-05-08 2010-11-11 Bommannan D Bommi Transdermal patch device
US20100324516A1 (en) 2009-06-18 2010-12-23 Tyco Healthcare Group Lp Apparatus for Vacuum Bridging and/or Exudate Collection
US8423131B2 (en) * 2009-06-26 2013-04-16 Incube Labs, Llc Corrosion resistant electrodes for iontophoretic transdermal delivery devices and methods of use
US8252971B2 (en) * 2009-07-16 2012-08-28 Aalnex, Inc. Systems and methods for protecting incisions
US20130018279A1 (en) * 2009-09-01 2013-01-17 Pathway Genomics "blood sample collection apparatus and kits"
CN102548475B (en) * 2009-09-24 2015-03-25 爱科来株式会社 Measuring device and measuring method
WO2011044175A2 (en) 2009-10-06 2011-04-14 Incube Labs, Llc Patch and patch assembly for iontophoretic transdermal delivery of active agents for therapeutic and medicinal purposes
US8834423B2 (en) 2009-10-23 2014-09-16 University of Pittsburgh—of the Commonwealth System of Higher Education Dissolvable microneedle arrays for transdermal delivery to human skin
US8685038B2 (en) 2009-12-07 2014-04-01 Incube Labs, Llc Iontophoretic apparatus and method for marking of the skin
US20110172638A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Drug delivery device including multi-functional cover
US8454975B1 (en) 2010-01-11 2013-06-04 Elizabeth VanderVeer Method for enhancing skin appearance
US20110178375A1 (en) * 2010-01-19 2011-07-21 Avery Dennison Corporation Remote physiological monitoring
US8986279B2 (en) 2010-02-10 2015-03-24 Incube Labs, Llc Methods and architecture for power optimization of iontophoretic transdermal drug delivery
WO2011112713A2 (en) * 2010-03-09 2011-09-15 Toxcure, Inc. Microneedle nasal delivery device
US8814842B2 (en) 2010-03-16 2014-08-26 Kci Licensing, Inc. Delivery-and-fluid-storage bridges for use with reduced-pressure systems
DK2563453T3 (en) 2010-04-28 2017-05-22 Kimberly Clark Co Nano-patterned medical device with improved cellular interaction and process for its preparation
CN102985131B (en) 2010-04-28 2016-06-29 金伯利-克拉克环球有限公司 For delivering the medical treatment device of siRNA
PT2563450T (en) 2010-04-28 2017-08-28 Kimberly Clark Co Device for delivery of rheumatoid arthritis medication
AU2011311255B2 (en) 2010-04-28 2015-10-08 Sorrento Therapeutics, Inc. Method for increasing permeability of an epithelial barrier
CA2795547A1 (en) 2010-04-28 2011-11-03 Inovio Pharmaceuticals, Inc. Oral mucosal electroporation device and use thereof
JP6327852B2 (en) 2010-05-04 2018-05-23 コリウム インターナショナル, インコーポレイテッド Methods and devices for transdermal delivery of parathyroid hormone using microprojection arrays
WO2011141426A1 (en) * 2010-05-10 2011-11-17 Tt Seed S.R.L. Needle device for detecting biosignals through the skin
CN102917751A (en) * 2010-05-28 2013-02-06 久光制药株式会社 Device having array provided with fine protrusions
TWI455722B (en) 2010-06-04 2014-10-11 Pfizer Vaccines Llc Conjugates for the prevention or treatment of nicotine addiction
WO2012061556A1 (en) 2010-11-03 2012-05-10 Flugen, Inc. Wearable drug delivery device having spring drive and sliding actuation mechanism
TWI433904B (en) * 2011-01-12 2014-04-11 Taiwan Biotech Co Ltd Donepezil transdermal patch
US8696637B2 (en) 2011-02-28 2014-04-15 Kimberly-Clark Worldwide Transdermal patch containing microneedles
WO2012129576A2 (en) 2011-03-24 2012-09-27 Incube Labs, Llc System and method for biphasic transdermal iontophreotic delivery of therapeutic agents
US10244981B2 (en) * 2011-03-30 2019-04-02 SensiVida Medical Technologies, Inc. Skin test image analysis apparatuses and methods thereof
WO2012154704A2 (en) 2011-05-06 2012-11-15 Incube Labs, Llc System and method for biphasic transdermal iontophoretic delivery of therapeutic agents for the control of addictive cravings
CN103945832B (en) * 2011-07-14 2017-03-29 能脑有限责任公司 For brain kinetomeres sustained release and the compositionss of sustained release, device and method
AU2012301814A1 (en) * 2011-08-31 2014-02-27 Perosphere Technologies Inc. Methods for effectively and rapidly desensitizing allergic patients
WO2013047410A1 (en) * 2011-09-28 2013-04-04 ニチバン株式会社 Long-acting adhesive skin patch for treating alzheimer's disease, and method for producing same
KR102022574B1 (en) 2011-10-12 2019-09-18 쓰리엠 이노베이티브 프로퍼티즈 컴파니 Integrated microneedle array delivery system
EP2771059B1 (en) 2011-10-27 2019-07-17 Sorrento Therapeutics, Inc. Transdermal delivery of high viscosity bioactive agents
US20170246439A9 (en) 2011-10-27 2017-08-31 Kimberly-Clark Worldwide, Inc. Increased Bioavailability of Transdermally Delivered Agents
RU2014119897A (en) 2011-10-27 2015-12-10 Кимберли-Кларк Ворлдвайд, Инк. IMPLANTABLE DEVICE FOR DELIVERY OF BIOACTIVE AGENT
JP5996862B2 (en) * 2011-11-04 2016-09-21 Asti株式会社 Microneedle array and microneedle array device
US10940047B2 (en) 2011-12-16 2021-03-09 Kci Licensing, Inc. Sealing systems and methods employing a hybrid switchable drape
EP3005997B1 (en) 2011-12-16 2024-06-26 Solventum Intellectual Properties Company Releasable medical drapes
TWI590843B (en) 2011-12-28 2017-07-11 信迪思有限公司 Films and methods of manufacture
JP5746101B2 (en) * 2012-06-18 2015-07-08 コスメディ製薬株式会社 Rapid dissolution method of microneedles
KR20150085837A (en) 2012-11-16 2015-07-24 케이씨아이 라이센싱 인코포레이티드 Medical drafe with pattern adhesive layers and method of manufacturing same
GB201220965D0 (en) * 2012-11-21 2013-01-02 Smidsy Ltd Light-projecting devices
AU2013364053B2 (en) 2012-12-21 2018-08-30 Corium Pharma Solutions, Inc. Microarray for delivery of therapeutic agent and methods of use
SG11201504909SA (en) * 2012-12-21 2015-07-30 3M Innovative Properties Co Adhesive assemblies and microneedle injection apparatuses comprising same
WO2014132240A1 (en) 2013-02-28 2014-09-04 Kimberly-Clark Worldwide, Inc. Transdermal drug delivery device
EP2961469A4 (en) 2013-02-28 2016-10-26 Kimberly Clark Co Drug delivery device
BR122020006959B1 (en) 2013-03-12 2022-04-26 Corium, Inc microprojection applicator
BR112015022625B1 (en) 2013-03-15 2023-01-31 Corium, Inc MICROSTRUCTURE DEVICE FOR DELIVERY OF THERAPEUTIC AGENT
US10898116B2 (en) * 2013-03-15 2021-01-26 Cambridge Medical Technologies LLC Methods of manufacture to optimize performance of transdermal sampling and analysis device
JP2016514133A (en) 2013-03-15 2016-05-19 コリウム インターナショナル, インコーポレイテッド MICROARRAY CONTAINING FINE STRUCTURE CONTAINING NO POLYMER, MANUFACTURING METHOD AND USE METHOD
CA2903459C (en) * 2013-03-15 2024-02-20 Corium International, Inc. Multiple impact microprojection applicators and methods of use
EP2968119B1 (en) 2013-03-15 2019-09-18 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
JP5806701B2 (en) * 2013-05-07 2015-11-10 日本写真印刷株式会社 Method for producing transdermal patch and transdermal patch
US20160144067A1 (en) 2013-06-21 2016-05-26 DePuy Synthes Products, Inc. Films and methods of manufacture
CN111744101B (en) * 2013-09-30 2023-03-10 佐治亚科技研究公司 Microneedle patches, systems, and methods
WO2015065742A1 (en) 2013-10-28 2015-05-07 Kci Licensing, Inc. Hybrid sealing tape
EP3173054B1 (en) 2013-10-30 2018-04-25 KCI Licensing, Inc. Dressing with diffrentially sized perforations
US9956120B2 (en) 2013-10-30 2018-05-01 Kci Licensing, Inc. Dressing with sealing and retention interface
EP3744361B1 (en) 2013-10-30 2024-07-24 Solventum Intellectual Properties Company Absorbent conduit and system
EP3257486B1 (en) 2013-10-30 2019-06-05 KCI Licensing, Inc. Condensate absorbing and dissipating system
US10632020B2 (en) 2014-02-28 2020-04-28 Kci Licensing, Inc. Hybrid drape having a gel-coated perforated mesh
US11026844B2 (en) 2014-03-03 2021-06-08 Kci Licensing, Inc. Low profile flexible pressure transmission conduit
EP3134149A4 (en) 2014-04-24 2017-12-27 Georgia Tech Research Corporation Microneedles and methods of manufacture thereof
US9962536B2 (en) 2014-04-30 2018-05-08 Kimberly-Clark Worldwide, Inc. Draped microneedle array
EP3137029B1 (en) * 2014-05-02 2020-09-09 KCI Licensing, Inc. Fluid storage devices, systems, and methods
US11607026B2 (en) * 2014-05-30 2023-03-21 Johnson & Johnson Consumer Inc. Device for delivery of skin care composition
EP3151795B1 (en) 2014-06-05 2017-09-27 KCI Licensing, Inc. Dressing with fluid acquisition and distribution characteristics
EP3188714A1 (en) 2014-09-04 2017-07-12 Corium International, Inc. Microstructure array, methods of making, and methods of use
DE102014114477B3 (en) * 2014-10-06 2016-02-25 Leica Microsystems (Schweiz) Ag Digital microscope with a radial piston brake system
DE102014114478B3 (en) * 2014-10-06 2016-02-25 Leica Microsystems (Schweiz) Ag Digital microscope with spring-mounted swiveling unit
DE102014114479B3 (en) * 2014-10-06 2016-02-25 Leica Microsystems (Schweiz) Ag DIGITAL MICROSCOPE WITH CLICK STOP
KR102172135B1 (en) * 2014-12-05 2020-10-30 히사미쓰 세이야꾸 가부시키가이샤 Microneedle device system
US10398604B2 (en) 2014-12-17 2019-09-03 Kci Licensing, Inc. Dressing with offloading capability
US10441768B2 (en) 2015-03-18 2019-10-15 University of Pittsburgh—of the Commonwealth System of Higher Education Bioactive components conjugated to substrates of microneedle arrays
JP2015134288A (en) * 2015-05-07 2015-07-27 コスメディ製薬株式会社 Rapid dissolution method for microneedle
EP3294245B1 (en) 2015-05-08 2019-09-04 KCI Licensing, Inc. Low acuity dressing with integral pump
WO2017004067A1 (en) 2015-06-29 2017-01-05 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
EP3344205B1 (en) * 2015-09-01 2020-09-30 KCI Licensing, Inc. Dressing with increased apposition force
EP3349807B1 (en) 2015-09-17 2021-02-24 3M Innovative Properties Company Hybrid silicone and acrylic adhesive cover for use with wound treatment
US11684763B2 (en) 2015-10-16 2023-06-27 University of Pittsburgh—of the Commonwealth System of Higher Education Multi-component bio-active drug delivery and controlled release to the skin by microneedle array devices
WO2017120322A1 (en) * 2016-01-05 2017-07-13 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Skin microenvironment targeted delivery for promoting immune and other responses
KR102377747B1 (en) * 2016-03-16 2022-03-23 코스메드 파마소티컬 씨오 쩜 엘티디 microneedle patch case
WO2017173478A1 (en) * 2016-04-06 2017-10-12 Mupharma Pty Ltd Acoustic wave mediated non-invasive drug delivery
CN106110490A (en) * 2016-06-21 2016-11-16 唐晨 The method and device that a kind of soft capsule micro-spray formula is microneedle cutaneous
CN110167625B (en) * 2017-01-25 2023-03-03 考司美德制药株式会社 Microneedle patch application device
JP6832456B2 (en) 2017-03-24 2021-02-24 イー インク カリフォルニア, エルエルシー Microcell delivery system containing charged or magnetic particles for adjusting the dosing rate of active molecules
KR102290262B1 (en) * 2017-03-24 2021-08-13 이 잉크 캘리포니아 엘엘씨 Microcell systems for delivering active molecules
US10780201B2 (en) 2017-07-29 2020-09-22 Edward D. Lin Control apparatus and related methods for wound therapy delivery
US12036353B2 (en) 2017-07-29 2024-07-16 Edward D. Lin Apparatus and methods for pressure management within a wound chamber
US11712373B2 (en) 2017-07-29 2023-08-01 Edward D. Lin Wound therapy apparatus with scar modulation properties and related methods
US10729826B2 (en) 2017-07-29 2020-08-04 Edward D. Lin Wound cover apparatus and related methods of use
US11559622B2 (en) 2017-07-29 2023-01-24 Edward D. Lin Deformation resistant wound therapy apparatus and related methods of use
WO2019099323A1 (en) * 2017-11-14 2019-05-23 E Ink California, Llc Microcell systems for delivering hydrophilic active molecules
CN111295182A (en) 2017-11-14 2020-06-16 伊英克加利福尼亚有限责任公司 Electrophoretic active substance delivery system comprising a porous conductive electrode layer
US11246997B2 (en) * 2018-09-25 2022-02-15 Palo Alto Research Center Incorporated Handheld filament extension atomizer for precision delivery of drugs and therapeutics
US11633129B2 (en) 2019-04-05 2023-04-25 Cambridge Medical Technologies LLC Non-invasive transdermal sampling and analysis device incorporating redox cofactors
US11375931B2 (en) 2019-08-08 2022-07-05 Cambridge Medical Technologies LLC Non-invasive transdermal sampling and analysis device incorporating an electrochemical bioassay
CN114728155B (en) 2019-11-27 2024-04-26 伊英克公司 Benefit agent delivery system including microcells with electrolytic seal layers
CN116322881A (en) 2020-10-29 2023-06-23 伊英克加利福尼亚有限责任公司 Microcell systems for delivering benefit agents
EP4236927A4 (en) 2020-10-29 2024-10-16 E Ink Corp Microcell systems for delivering hydrophilic active molecules
DE102021121528A1 (en) * 2021-08-19 2023-02-23 Lts Lohmann Therapie-Systeme Ag. Microneedle device and method for detecting at least one force acting on a microneedle array
CA3236242A1 (en) * 2021-12-13 2023-06-22 Stephen Welsh Adhesive bandage system for medication delivery and indication of procedure location

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6132755A (en) * 1995-07-14 2000-10-17 Boehringer Ingelheim Kg Transcorneal drug-release system
WO2000074763A2 (en) * 1999-06-04 2000-12-14 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
WO2003026733A2 (en) * 2001-09-28 2003-04-03 Biovalve Technologies, Inc. Microneedle with membrane
US6611707B1 (en) * 1999-06-04 2003-08-26 Georgia Tech Research Corporation Microneedle drug delivery device

Family Cites Families (239)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1554510A (en) 1924-04-23 1925-09-22 Elsie W Kirby Massaging device
US1770632A (en) 1928-07-02 1930-07-15 Arthur E Smith Ampul syringe
US2046240A (en) 1932-07-01 1936-06-30 Thomas W Bayley Abrasive article
US2434407A (en) 1946-01-05 1948-01-13 Hofe George Douglas Depilatory device
US3675766A (en) 1970-02-04 1972-07-11 Sol Roy Rosenthal Multiple puncture injector device
US3704194A (en) 1970-07-02 1972-11-28 Gen Electric Perforated reinforced plastic member and method for making
US3917785A (en) 1971-01-27 1975-11-04 Johnson & Johnson Method for producing nonwoven fabric
US3964482A (en) * 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
BE795384A (en) 1972-02-14 1973-08-13 Ici Ltd DRESSINGS
FR2232331B1 (en) 1973-06-06 1978-03-24 Guerin A Ets
AT347283B (en) 1975-03-07 1978-12-27 Collo Gmbh FOAM BODY FOR CLEANING, SCRUBBING AND / OR POLISHING PURPOSES AND THE LIKE.
US4151240A (en) 1976-10-19 1979-04-24 The Procter & Gamble Company Method for debossing and perforating a running ribbon of thermoplastic film
US4180232A (en) 1977-01-13 1979-12-25 Hardigg James S Truss panel mold
US4117841A (en) * 1977-02-07 1978-10-03 Anthony Perrotta Medicated bandage pocket
US4342314A (en) 1979-03-05 1982-08-03 The Procter & Gamble Company Resilient plastic web exhibiting fiber-like properties
US4402696A (en) * 1979-10-15 1983-09-06 Gulko Bruce N Folded applicator
US4381963A (en) 1980-07-30 1983-05-03 The University Of Rochester Micro fabrication molding process
US4395215A (en) 1981-02-02 1983-07-26 The Procter & Gamble Company Film forming structure for uniformly debossing and selectively aperturing a resilient plastic web and method for its construction
US4509908A (en) 1981-02-02 1985-04-09 The Procter & Gamble Company Apparatus for uniformly debossing and aperturing a resilient plastic web
US4463045A (en) 1981-03-02 1984-07-31 The Procter & Gamble Company Macroscopically expanded three-dimensional plastic web exhibiting non-glossy visible surface and cloth-like tactile impression
US4460370A (en) * 1981-10-29 1984-07-17 Almedco, Inc. Trans-dermal medication application cell
US4460368A (en) * 1981-10-29 1984-07-17 Almedco, Inc. Trans-dermal medication system
US4966159A (en) * 1981-12-14 1990-10-30 Maganias Nicholas H Allergy test strip
US4585991A (en) 1982-06-03 1986-04-29 Texas Instruments Incorporated Solid state multiprobe testing apparatus
FR2535602B1 (en) 1982-11-05 1986-06-13 Stallergenes Lab SCARIFIER DEVICE
US4556441A (en) * 1983-01-24 1985-12-03 Faasse Jr Adrian L Pharmaceutical packaging method
US4515168A (en) 1983-07-22 1985-05-07 Chester Martin H Clamp-on nerve stimulator and locator
US4708716A (en) 1983-08-18 1987-11-24 Drug Delivery Systems Inc. Transdermal drug applicator
US5591123A (en) 1983-08-18 1997-01-07 Drug Delivery Systems Inc. Programmable control mounting system for transdermal drug applicator
US4695422A (en) 1984-02-16 1987-09-22 The Procter & Gamble Company Production of formed material by solid-state formation with a high-pressure liquid stream
US4583982A (en) 1984-08-24 1986-04-22 Vlock D G Fluid dispenser
US5135477A (en) 1984-10-29 1992-08-04 Medtronic, Inc. Iontophoretic drug delivery
US4597961A (en) * 1985-01-23 1986-07-01 Etscorn Frank T Transcutaneous application of nicotine
US4904475A (en) * 1985-05-03 1990-02-27 Alza Corporation Transdermal delivery of drugs from an aqueous reservoir
US4609518A (en) 1985-05-31 1986-09-02 The Procter & Gamble Company Multi-phase process for debossing and perforating a polymeric web to coincide with the image of one or more three-dimensional forming structures
US4630603A (en) 1986-02-13 1986-12-23 The Kendall Company Wound dressing
US4743249A (en) * 1986-02-14 1988-05-10 Ciba-Geigy Corp. Dermal and transdermal patches having a discontinuous pattern adhesive layer
AU597890B2 (en) 1986-03-14 1990-06-14 Drug Delivery Systems Inc. Transdermal drug applicator and electrodes therefor
US4784737A (en) 1986-04-18 1988-11-15 The United States Department Of Energy Electromicroinjection of particles into living cells
US4837049A (en) 1986-06-17 1989-06-06 Alfred E. Mann Foundation For Scientific Research Method of making an electrode array
US4842794A (en) 1987-07-30 1989-06-27 Applied Extrusion Technologies, Inc. Method of making apertured films and net like fabrics
US5061258A (en) * 1987-08-07 1991-10-29 Martz Joel D Vapor permeable dressing with releasable medication
US4846821A (en) 1987-08-24 1989-07-11 The Procter & Gamble Company Substantially fluid-impervious microbubbled polymeric web exhibiting low levels of noise when subjected to movement
US4812305A (en) * 1987-11-09 1989-03-14 Vocal Rodolfo S Well medicine strip
SU1641346A1 (en) 1987-12-08 1991-04-15 Мгту Им.Н.Э.Баумана Electrostimulation appliance
DK157899C (en) * 1987-12-15 1990-09-03 Coloplast As A dressing
FR2625937B1 (en) 1988-01-19 1993-04-30 Vuillaume Andre METHOD AND DEVICE FOR PERFORATING A SHEET PRODUCT, AND PERFORATED PRODUCT THUS OBTAINED
US5362307A (en) 1989-01-24 1994-11-08 The Regents Of The University Of California Method for the iontophoretic non-invasive-determination of the in vivo concentration level of an inorganic or organic substance
US5198192A (en) 1988-05-18 1993-03-30 Inax Corporation Apparatus for detecting ingredient in urine, a toilet stool equipped with a urine detecting device and a room for urine detecting facility
GB2221394B (en) 1988-08-05 1992-03-04 Eilert Eilertsen An injection device
DE3844247A1 (en) * 1988-12-29 1990-07-12 Minnesota Mining & Mfg DEVICE, IN PARTICULAR PLASTER FOR TRANSDERMAL ADMINISTRATION OF A MEDICINAL PRODUCT
SU1667864A1 (en) 1989-03-23 1991-08-07 Опытный завод энергетического машиностроения Electrostimulation device
US5134079A (en) 1989-03-27 1992-07-28 International Technidyne Corp. Fluid sample collection and delivery system and methods particularly adapted for body fluid sampling
US5788983A (en) * 1989-04-03 1998-08-04 Rutgers, The State University Of New Jersey Transdermal controlled delivery of pharmaceuticals at variable dosage rates and processes
US5531675A (en) 1989-05-10 1996-07-02 Yoo; Tae W. Micro-acupuncture needle for a finger of a hand
CA2016900A1 (en) 1989-07-06 1991-01-06 Ronald J. Filipski Tines structure in clinical applicator
EP0429842B1 (en) * 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Device for the transdermal administration of protein or peptide drug
US5215088A (en) 1989-11-07 1993-06-01 The University Of Utah Three-dimensional electrode device
US5190558A (en) 1989-11-08 1993-03-02 Nec Corporation Method of eliminating stratum corneum from the skin and an instrument to be used therefor
US5697901A (en) 1989-12-14 1997-12-16 Elof Eriksson Gene delivery by microneedle injection
US5244711A (en) 1990-03-12 1993-09-14 Mcneil-Ppc, Inc. Apertured non-woven fabric
US5162043A (en) 1990-03-30 1992-11-10 Alza Corporation Iontophoretic delivery device
US5139029A (en) 1990-04-06 1992-08-18 Henry Fishman Allergy testing apparatus and method
US5156591A (en) 1990-12-13 1992-10-20 S. I. Scientific Innovations Ltd. Skin electrode construction and transdermal drug delivery device utilizing same
US5527288A (en) 1990-12-13 1996-06-18 Elan Medical Technologies Limited Intradermal drug delivery device and method for intradermal delivery of drugs
TW279133B (en) 1990-12-13 1996-06-21 Elan Med Tech
US5279544A (en) 1990-12-13 1994-01-18 Sil Medics Ltd. Transdermal or interdermal drug delivery devices
US5158073A (en) 1990-12-18 1992-10-27 Bukowski Voytek Z Acupressure foot massage mat
US5252279A (en) 1991-01-17 1993-10-12 Reinhold Industries Method for making perforated articles
US5312456A (en) 1991-01-31 1994-05-17 Carnegie Mellon University Micromechanical barb and method for making the same
US5160315A (en) 1991-04-05 1992-11-03 Minnesota Mining And Manufacturing Company Combined adhesive strip and transparent dressing delivery system
TW273531B (en) 1991-08-14 1996-04-01 Chicopee Textile-like apertured plastic films
US5256360A (en) 1992-03-25 1993-10-26 Panasonic Technologies, Inc. Method of manufacturing a precision micro-filter
US5756117A (en) * 1992-04-08 1998-05-26 International Medical Asscociates, Inc. Multidose transdermal drug delivery system
IE930532A1 (en) 1993-07-19 1995-01-25 Elan Med Tech Liquid material dispenser and valve
US5318557A (en) 1992-07-13 1994-06-07 Elan Medical Technologies Limited Medication administering device
US5308625A (en) * 1992-09-02 1994-05-03 Cygnus Therapeutic Systems Enhancement of transdermal drug delivery using monoalkyl phosphates and other absorption promoters
US5462743A (en) * 1992-10-30 1995-10-31 Medipro Sciences Limited Substance transfer system for topical application
US5250067A (en) 1992-11-30 1993-10-05 Ala Gelfer Body treatment pad having a multiple number of sharpened skin-penetration protuberances
US5383512A (en) 1993-01-27 1995-01-24 Midwest Research Institute Method for fabricating a substrate having spaced apart microcapillaries thereon
GB9305930D0 (en) 1993-03-22 1993-05-12 Moran Peter L Electrical circuit board
KR100355857B1 (en) 1993-03-22 2003-03-31 미네소타 마이닝 앤드 매뉴팩춰링 캄파니 Adhesive composite dressing and manufacturing method
US6685682B1 (en) 1993-03-22 2004-02-03 3M Innovative Properties Company Carrier delivered dressing and method of manufacture
NZ250994A (en) * 1993-05-27 1995-09-26 Ndm Acquisition Corp Wound dressing comprising a hydrogel layer bound to a porous backing layer which is bound to a thin film layer by adhesive
US5330452A (en) * 1993-06-01 1994-07-19 Zook Gerald P Topical medicating device
US5728089A (en) 1993-06-04 1998-03-17 The Regents Of The University Of California Microfabricated structure to be used in surgery
US5320600A (en) 1993-06-14 1994-06-14 Lambert Wm S Plural content container for simultaneous ejection
CA2132277C (en) 1993-10-22 2005-05-10 Giorgio Cirelli Injection device
US5962011A (en) * 1993-12-06 1999-10-05 Schering-Plough Healthcare Products, Inc. Device for delivery of dermatological ingredients
US5457041A (en) 1994-03-25 1995-10-10 Science Applications International Corporation Needle array and method of introducing biological substances into living cells using the needle array
US5536263A (en) 1994-03-30 1996-07-16 Lectec Corporation Non-occulusive adhesive patch for applying medication to the skin
US5503843A (en) * 1994-04-22 1996-04-02 Flora Inc. Transdermal delivery of alpha adrenoceptor blocking agents
CA2149836C (en) 1994-05-23 1999-07-06 Sang Bae Choi Perforating device for dermal administration
US5611806A (en) 1994-05-23 1997-03-18 Samsung Electro-Mechanics Co., Ltd. Skin perforating device for transdermal medication
KR0134151B1 (en) 1994-05-23 1998-04-14 이형도 Insulin patch
KR0134152B1 (en) 1994-05-23 1998-04-14 이형도 Skin treatment device for medication
US5851549A (en) * 1994-05-25 1998-12-22 Becton Dickinson And Company Patch, with system and apparatus for manufacture
US5512219A (en) 1994-06-03 1996-04-30 Reflexite Corporation Method of casting a microstructure sheet having an array of prism elements using a reusable polycarbonate mold
US5591139A (en) 1994-06-06 1997-01-07 The Regents Of The University Of California IC-processed microneedles
US5487726A (en) 1994-06-16 1996-01-30 Ryder International Corporation Vaccine applicator system
US5771890A (en) 1994-06-24 1998-06-30 Cygnus, Inc. Device and method for sampling of substances using alternating polarity
US5496304A (en) 1994-07-20 1996-03-05 University Of Utah Research Foundation Surgical marking pen
US5498235A (en) 1994-09-30 1996-03-12 Becton Dickinson And Company Iontophoresis assembly including patch/controller attachment
US5551953A (en) 1994-10-31 1996-09-03 Alza Corporation Electrotransport system with remote telemetry link
IE72524B1 (en) 1994-11-04 1997-04-23 Elan Med Tech Analyte-controlled liquid delivery device and analyte monitor
US6120488A (en) 1994-11-28 2000-09-19 The Procter & Gamble Company Absorbent articles having cuffs and topsheet with skin care composition(s) disposed thereon
ATE177325T1 (en) 1994-12-09 1999-03-15 Novartis Erfind Verwalt Gmbh TRANSDERMAL SYSTEM
AU5740496A (en) 1995-05-22 1996-12-11 General Hospital Corporation, The Micromechanical device and method for enhancing delivery of compounds through the skin
IE77523B1 (en) 1995-09-11 1997-12-17 Elan Med Tech Medicament delivery device
US5735273A (en) 1995-09-12 1998-04-07 Cygnus, Inc. Chemical signal-impermeable mask
US5645977A (en) 1995-09-22 1997-07-08 Industrial Technology Research Institute Method of making molds for manufacturing multiple-lead microstructures
US5658515A (en) 1995-09-25 1997-08-19 Lee; Abraham P. Polymer micromold and fabrication process
US5662127A (en) 1996-01-17 1997-09-02 Bio-Plas, Inc. Self-contained blood withdrawal apparatus and method
US5730721A (en) * 1996-01-25 1998-03-24 Vesture Corporation Medical applicator and method
JP3430771B2 (en) 1996-02-05 2003-07-28 株式会社デンソー Method of manufacturing semiconductor dynamic quantity sensor
JPH09215755A (en) 1996-02-09 1997-08-19 Poritoronikusu:Kk Skin contact treating implement
US5948488A (en) 1996-04-30 1999-09-07 3M Innovative Properties Company Glittering cube-corner article
ZA975326B (en) 1996-06-18 1998-01-14 Alza Corp Device and method for enhancing transdermal flux of agents being delivered or sampled.
DE19624578A1 (en) 1996-06-20 1998-01-08 Nancy L Divers Skin care device
ES2200187T3 (en) 1996-07-03 2004-03-01 Altea Therapeutics Corporation MULTIPLE MECHANICAL MICROPORATION OF THE SKIN OR MUCOSA.
US6512010B1 (en) * 1996-07-15 2003-01-28 Alza Corporation Formulations for the administration of fluoxetine
CA2265906C (en) 1996-09-17 2003-11-11 Deka Products Limited Partnership System for delivery of drugs by transport
DE19649100A1 (en) * 1996-11-27 1998-06-04 Lohmann Therapie Syst Lts Process for the low-loss production of disk-shaped shaped articles containing active ingredients and transdermal therapeutic systems containing them
US5873849A (en) 1997-04-24 1999-02-23 Ichor Medical Systems, Inc. Electrodes and electrode arrays for generating electroporation inducing electrical fields
US5904712A (en) 1997-06-12 1999-05-18 Axelgaard Manufacturing Co., Ltd. Current-controlling electrode
US5928207A (en) 1997-06-30 1999-07-27 The Regents Of The University Of California Microneedle with isotropically etched tip, and method of fabricating such a device
US6241701B1 (en) 1997-08-01 2001-06-05 Genetronics, Inc. Apparatus for electroporation mediated delivery of drugs and genes
US6216034B1 (en) 1997-08-01 2001-04-10 Genetronics, Inc. Method of programming an array of needle electrodes for electroporation therapy of tissue
US6055453A (en) 1997-08-01 2000-04-25 Genetronics, Inc. Apparatus for addressing needle array electrodes for electroporation therapy
US6047208A (en) 1997-08-27 2000-04-04 Becton, Dickinson And Company Iontophoretic controller
US20010023324A1 (en) 1997-11-03 2001-09-20 Allan Pronovost Glucose detector and method for diagnosing diabetes
US5938684A (en) 1997-12-09 1999-08-17 Sierra Self Healing Products, Inc. Accupressure device for therapeutic relief
US6918901B1 (en) 1997-12-10 2005-07-19 Felix Theeuwes Device and method for enhancing transdermal agent flux
CA2313698C (en) 1997-12-11 2008-04-15 Alza Corporation Device for enhancing transdermal agent flux
KR100572539B1 (en) 1997-12-11 2006-04-24 알자 코포레이션 Device for enhancing transdermal agent flux
ATE406935T1 (en) 1997-12-11 2008-09-15 Alza Corp DEVICE FOR IMPROVING THE TRANSDERMAL FLOW OF MEDICATIONS
US6778853B1 (en) 1997-12-17 2004-08-17 University Of South Florida Electroporation device
US6135990A (en) 1997-12-17 2000-10-24 University Of South Florida Electroporation device and method
JP4215188B2 (en) 1997-12-22 2009-01-28 インターシア セラピューティクス,インコーポレイティド Rate-regulating membranes for devices that regulate drug delivery
US6024553A (en) 1997-12-22 2000-02-15 Mcneil-Ppc, Inc. Apparatus for supporting a starting web during formation of the apertured web
US6106751A (en) 1998-03-18 2000-08-22 The Regents Of The University Of California Method for fabricating needles via conformal deposition in two-piece molds
US6091975A (en) 1998-04-01 2000-07-18 Alza Corporation Minimally invasive detecting device
US6120792A (en) * 1998-04-29 2000-09-19 Juni; Jack E. Medicated skin patch and method for its use
US6503231B1 (en) 1998-06-10 2003-01-07 Georgia Tech Research Corporation Microneedle device for transport of molecules across tissue
EP1086214B1 (en) 1998-06-10 2009-11-25 Georgia Tech Research Corporation Microneedle devices and methods of their manufacture
GB9815819D0 (en) 1998-07-22 1998-09-16 Secr Defence Transferring materials into cells and a microneedle array
WO2000012173A1 (en) 1998-08-31 2000-03-09 Johnson & Johnson Consumer Companies, Inc. Electrotransport device comprising blades
JP2000146777A (en) 1998-09-08 2000-05-26 Matsushita Electric Ind Co Ltd Method and device for specimen sampling, container for sampling specimen, specimen measuring method and device, and container for measuring specimen
US6036659A (en) 1998-10-09 2000-03-14 Flexsite Diagnostics, Inc. Collection device for biological samples and methods of use
US6038465A (en) 1998-10-13 2000-03-14 Agilent Technologies, Inc. Telemedicine patient platform
US6611706B2 (en) 1998-11-09 2003-08-26 Transpharma Ltd. Monopolar and bipolar current application for transdermal drug delivery and analyte extraction
EP1003078A3 (en) 1998-11-17 2001-11-07 Corning Incorporated Replicating a nanoscale pattern
JP4214584B2 (en) 1998-11-27 2009-01-28 株式会社デンソー Semiconductor dynamic quantity sensor and manufacturing method thereof
JP2000194142A (en) 1998-12-25 2000-07-14 Fujitsu Ltd Pattern forming method and production of semiconductor device
JP2000232095A (en) 1999-02-12 2000-08-22 Nippon Telegr & Teleph Corp <Ntt> Formation method for fine pattern of semiconductor surface
JP2000232971A (en) 1999-02-15 2000-08-29 Arkray Inc Sucked transudate sampling method and device
US5997549A (en) 1999-02-16 1999-12-07 Sauceda; Charles J. Wart removing tool
US6132449A (en) 1999-03-08 2000-10-17 Agilent Technologies, Inc. Extraction and transportation of blood for analysis
US6183770B1 (en) * 1999-04-15 2001-02-06 Acutek International Carrier patch for the delivery of agents to the skin
US6689103B1 (en) 1999-05-07 2004-02-10 Scimed Life System, Inc. Injection array apparatus and method
JP2000323461A (en) 1999-05-11 2000-11-24 Nec Corp Fine pattern forming device, its manufacture, and method of forming the same
JP4114761B2 (en) 1999-05-14 2008-07-09 国立大学法人群馬大学 STAMPER FOR INFORMATION RECORDING DISC, ITS MANUFACTURING METHOD, INFORMATION RECORDING DISC, AND INFORMATION RECORDING DISK MANUFACTURING METHOD
US6743211B1 (en) 1999-11-23 2004-06-01 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
US6256533B1 (en) 1999-06-09 2001-07-03 The Procter & Gamble Company Apparatus and method for using an intracutaneous microneedle array
US6312612B1 (en) 1999-06-09 2001-11-06 The Procter & Gamble Company Apparatus and method for manufacturing an intracutaneous microneedle array
US6379324B1 (en) * 1999-06-09 2002-04-30 The Procter & Gamble Company Intracutaneous microneedle array apparatus
JP3654059B2 (en) 1999-06-25 2005-06-02 松下電工株式会社 Infrared sensor manufacturing method
JP3387897B2 (en) 1999-08-30 2003-03-17 キヤノン株式会社 Structure manufacturing method, structure manufactured by the manufacturing method, and structure device using the structure
US6623457B1 (en) * 1999-09-22 2003-09-23 Becton, Dickinson And Company Method and apparatus for the transdermal administration of a substance
US6835184B1 (en) 1999-09-24 2004-12-28 Becton, Dickinson And Company Method and device for abrading skin
IT1308847B1 (en) * 1999-09-28 2002-01-11 Alpitel Spa METHOD AND OPERATING MACHINE FOR THE INSTALLATION OF WIRING AND / OR INFRASTRUCTURE.
US20030093089A1 (en) 1999-10-20 2003-05-15 Greenberg Ronald Allan Apparatus for variable micro abrasion of human tissue and/or hides using different size and types of abrasive particles
US6355054B1 (en) 1999-11-05 2002-03-12 Ceramoptec Industries, Inc. Laser system for improved transbarrier therapeutic radiation delivery
US6511463B1 (en) 1999-11-18 2003-01-28 Jds Uniphase Corporation Methods of fabricating microneedle arrays using sacrificial molds
DE60024312T2 (en) 1999-12-10 2006-08-17 Alza Corp., Mountain View Transdermal drug delivery of macromolecular agents and device therefor
DK1239917T3 (en) 1999-12-10 2005-08-22 Alza Corp Skin care device for sustained transdermal drug delivery
ES2239053T3 (en) 1999-12-16 2005-09-16 Alza Corporation DEVICE FOR INCREASING THE TRANSDERMAL FLOW OF SAMPLING SUBSTANCES.
US6375627B1 (en) 2000-03-02 2002-04-23 Agilent Technologies, Inc. Physiological fluid extraction with rapid analysis
US6558361B1 (en) 2000-03-09 2003-05-06 Nanopass Ltd. Systems and methods for the transport of fluids through a biological barrier and production techniques for such systems
US6629949B1 (en) 2000-05-08 2003-10-07 Sterling Medivations, Inc. Micro infusion drug delivery device
US6565532B1 (en) 2000-07-12 2003-05-20 The Procter & Gamble Company Microneedle apparatus used for marking skin and for dispensing semi-permanent subcutaneous makeup
JP4001311B2 (en) 2000-06-01 2007-10-31 株式会社リコー Droplet discharge head, inkjet recording device, microactuator
US6537242B1 (en) 2000-06-06 2003-03-25 Becton, Dickinson And Company Method and apparatus for enhancing penetration of a member for the intradermal sampling or administration of a substance
US6494830B1 (en) 2000-06-22 2002-12-17 Guidance Interactive Technologies, Inc. Handheld controller for monitoring/using medical parameters
US6589202B1 (en) 2000-06-29 2003-07-08 Becton Dickinson And Company Method and apparatus for transdermally sampling or administering a substance to a patient
US6603987B2 (en) 2000-07-11 2003-08-05 Bayer Corporation Hollow microneedle patch
US6440096B1 (en) 2000-07-14 2002-08-27 Becton, Dickinson And Co. Microdevice and method of manufacturing a microdevice
US6656147B1 (en) * 2000-07-17 2003-12-02 Becton, Dickinson And Company Method and delivery device for the transdermal administration of a substance
GB0017999D0 (en) 2000-07-21 2000-09-13 Smithkline Beecham Biolog Novel device
JP2002079499A (en) 2000-09-08 2002-03-19 Terumo Corp Method of manufacturing needle-like article, and manufactured needle
US6691752B2 (en) 2000-09-15 2004-02-17 Timberjack Inc. High rotation felling head mechanism
WO2002028471A1 (en) 2000-10-05 2002-04-11 Thomas Marsoner Medical injection device
HUP0303576A2 (en) 2000-10-13 2004-01-28 Alza Corp Microprotrusion member retainer for impact applicator
AU9682801A (en) 2000-10-13 2002-04-22 Alza Corp Apparatus and method for piercing skin with microprotrusions
IL155375A0 (en) 2000-10-13 2003-11-23 Alza Corp Microblade array impact applicator
US7828827B2 (en) 2002-05-24 2010-11-09 Corium International, Inc. Method of exfoliation of skin using closely-packed microstructures
US6821281B2 (en) 2000-10-16 2004-11-23 The Procter & Gamble Company Microstructures for treating and conditioning skin
US7131987B2 (en) 2000-10-16 2006-11-07 Corium International, Inc. Microstructures and method for treating and conditioning skin which cause less irritation during exfoliation
US6533884B1 (en) 2000-11-03 2003-03-18 Printpack Illinois, Inc. Method and system for extrusion embossing
JP3525177B2 (en) 2000-11-14 2004-05-10 関西ティー・エル・オー株式会社 Material processing method using X-ray
US6591133B1 (en) 2000-11-27 2003-07-08 Microlin Llc Apparatus and methods for fluid delivery using electroactive needles and implantable electrochemical delivery devices
EP1345646A2 (en) 2000-12-14 2003-09-24 Georgia Tech Research Corporation Microneedle devices and production thereof
US6508947B2 (en) 2001-01-24 2003-01-21 Xerox Corporation Method for fabricating a micro-electro-mechanical fluid ejector
JP3696513B2 (en) 2001-02-19 2005-09-21 住友精密工業株式会社 Manufacturing method of needle-shaped body
US6663820B2 (en) 2001-03-14 2003-12-16 The Procter & Gamble Company Method of manufacturing microneedle structures using soft lithography and photolithography
CN100349632C (en) 2001-04-20 2007-11-21 阿尔扎公司 Microprojection array having beneficial agent contg coating
US20020193729A1 (en) * 2001-04-20 2002-12-19 Cormier Michel J.N. Microprojection array immunization patch and method
US6585742B2 (en) 2001-05-08 2003-07-01 Dowling B. Stough Wart removal method and device
US6591124B2 (en) 2001-05-11 2003-07-08 The Procter & Gamble Company Portable interstitial fluid monitoring system
DE60213976T2 (en) 2001-06-08 2007-04-26 Becton Dickinson And Co. DEVICE FOR MANIPULATING NEEDLES OR POLISHING ARRAY
US6767341B2 (en) 2001-06-13 2004-07-27 Abbott Laboratories Microneedles for minimally invasive drug delivery
US20040204669A1 (en) 2001-07-05 2004-10-14 Hofmann Gunter A. Apparatus for electroporation mediated delivery for drugs and genes
US6749792B2 (en) 2001-07-09 2004-06-15 Lifescan, Inc. Micro-needles and methods of manufacture and use thereof
JP5055672B2 (en) 2001-07-31 2012-10-24 大日本印刷株式会社 Thin film pattern forming stamp
JP4919446B2 (en) 2001-08-09 2012-04-18 学校法人東京電機大学 Fine groove machining method and apparatus
US6881203B2 (en) 2001-09-05 2005-04-19 3M Innovative Properties Company Microneedle arrays and methods of manufacturing the same
US20040087992A1 (en) 2002-08-09 2004-05-06 Vladimir Gartstein Microstructures for delivering a composition cutaneously to skin using rotatable structures
AU2002327675A1 (en) 2001-09-19 2003-04-01 Biovalve Technologies, Inc. Microneedles, microneedle arrays, and systems and methods relating to same
US20030093028A1 (en) 2001-11-09 2003-05-15 Michael Spiegel Appararus and method for magnetic induction of therapeutic electric fields
US20030199810A1 (en) 2001-11-30 2003-10-23 Trautman Joseph Creagan Methods and apparatuses for forming microprojection arrays
MXPA04007389A (en) 2002-02-04 2004-10-11 Becton Dickinson Co Device and method for delivering or withdrawing a substance through the skin.
US7115108B2 (en) * 2002-04-02 2006-10-03 Becton, Dickinson And Company Method and device for intradermally delivering a substance
US6780171B2 (en) 2002-04-02 2004-08-24 Becton, Dickinson And Company Intradermal delivery device
US6945952B2 (en) 2002-06-25 2005-09-20 Theraject, Inc. Solid solution perforator for drug delivery and other applications
AR040819A1 (en) 2002-08-08 2005-04-20 Alza Corp VACCINE TRANSDERMAL ADMINISTRATION DEVICE THAT HAS MICROPROJECTIONS COVERED
ES2617576T3 (en) 2002-08-29 2017-06-19 Becton, Dickinson And Company Substance administration through a rotating microabrasive system
CA2453013C (en) * 2002-12-13 2011-02-15 Gary W. Cleary Dermal, transdermal, mucosal or transmucosal ingredient delivery devices
US7578954B2 (en) 2003-02-24 2009-08-25 Corium International, Inc. Method for manufacturing microstructures having multiple microelements with through-holes
US7572405B2 (en) 2003-06-02 2009-08-11 Corium International Inc. Method for manufacturing microstructures having hollow microelements using fluidic jets during a molding operation
AU2004285481A1 (en) * 2003-10-24 2005-05-12 Alza Corporation Apparatus and method for enhancing transdermal drug delivery
JP4682144B2 (en) 2003-10-31 2011-05-11 アルザ・コーポレーシヨン Self-actuating applicator for microprojection arrays
AT500095B8 (en) * 2004-01-23 2007-02-15 Braun Werner Mag TRANSDERMAL DELIVERY SYSTEM
AU2005228145B2 (en) * 2004-03-24 2011-03-03 Corium Pharma Solutions, Inc. Transdermal delivery device
CN101060883B (en) 2004-11-18 2010-06-23 3M创新有限公司 Low-profile microneedle array applicator
WO2007002523A2 (en) 2005-06-24 2007-01-04 3M Innovative Properties Company Collapsible patch with microneedle array
EP2121111B1 (en) 2007-01-22 2018-03-14 Corium International, Inc. Applicators for microneedle arrays
US9114238B2 (en) 2007-04-16 2015-08-25 Corium International, Inc. Solvent-cast microprotrusion arrays containing active ingredient
US7578985B2 (en) 2007-04-18 2009-08-25 Gas Technology Institute Method for direct oxidation of hydrogen sulfide to elemental sulfur at low temperatures
WO2009048607A1 (en) 2007-10-10 2009-04-16 Corium International, Inc. Vaccine delivery via microneedle arrays

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6132755A (en) * 1995-07-14 2000-10-17 Boehringer Ingelheim Kg Transcorneal drug-release system
WO2000074763A2 (en) * 1999-06-04 2000-12-14 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
US6611707B1 (en) * 1999-06-04 2003-08-26 Georgia Tech Research Corporation Microneedle drug delivery device
WO2003026733A2 (en) * 2001-09-28 2003-04-03 Biovalve Technologies, Inc. Microneedle with membrane

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2005094526A2 *

Also Published As

Publication number Publication date
US7611481B2 (en) 2009-11-03
CA2560840A1 (en) 2005-10-13
US7914480B2 (en) 2011-03-29
US20100028390A1 (en) 2010-02-04
EP1737357B1 (en) 2019-12-11
CA2560840C (en) 2014-05-06
WO2005094526A2 (en) 2005-10-13
WO2005094526A3 (en) 2009-04-23
AU2005228145A1 (en) 2005-10-13
JP5085317B2 (en) 2012-11-28
EP1737357A2 (en) 2007-01-03
US20050228340A1 (en) 2005-10-13
AU2005228145B2 (en) 2011-03-03
JP2007535346A (en) 2007-12-06

Similar Documents

Publication Publication Date Title
EP1737357A4 (en) Transdermal delivery device
EP1765158A4 (en) Delivery device
IL183145A (en) Controlled-volume infusion device
EP1802258A4 (en) Biosynchronous transdermal drug delivery
PL3437682T3 (en) Drug delivery device
GB2422654B (en) Superconduction-technology device
EP1781355A4 (en) Drug delivery device
IL174894A0 (en) Transdermal drug delivery device
GB0405386D0 (en) Device
GB0425632D0 (en) Device
HK1104126A1 (en) Battery-recharging device
HK1080130B (en) Tool-switching device
GB0415112D0 (en) Therapeutic device
GB0424882D0 (en) Device
GB0417361D0 (en) Improved dispensing device
GB0520757D0 (en) Delivery device
PL1827178T3 (en) Infusing device
IL175893A0 (en) Anti-roosting device
GB0409197D0 (en) Device
GB0415190D0 (en) Device
GB2410441B (en) Magnotherapy device
GB0409689D0 (en) Retaining device
GB0414224D0 (en) Delivery device
GB0402698D0 (en) Delivery device
GB2419154B (en) Strap-adjusting device

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20060926

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL BA HR LV MK YU

DAX Request for extension of the european patent (deleted)
PUAK Availability of information related to the publication of the international search report

Free format text: ORIGINAL CODE: 0009015

RIC1 Information provided on ipc code assigned before grant

Ipc: A61N 1/30 20060101AFI20090622BHEP

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: CORIUM INTERNATIONAL, INC.

A4 Supplementary search report drawn up and despatched

Effective date: 20120608

RIC1 Information provided on ipc code assigned before grant

Ipc: A61M 37/00 20060101AFI20120601BHEP

17Q First examination report despatched

Effective date: 20120827

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: EXAMINATION IS IN PROGRESS

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: GRANT OF PATENT IS INTENDED

INTG Intention to grant announced

Effective date: 20190429

GRAJ Information related to disapproval of communication of intention to grant by the applicant or resumption of examination proceedings by the epo deleted

Free format text: ORIGINAL CODE: EPIDOSDIGR1

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: EXAMINATION IS IN PROGRESS

INTC Intention to grant announced (deleted)
GRAR Information related to intention to grant a patent recorded

Free format text: ORIGINAL CODE: EPIDOSNIGR71

GRAS Grant fee paid

Free format text: ORIGINAL CODE: EPIDOSNIGR3

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: GRANT OF PATENT IS INTENDED

GRAJ Information related to disapproval of communication of intention to grant by the applicant or resumption of examination proceedings by the epo deleted

Free format text: ORIGINAL CODE: EPIDOSDIGR1

GRAR Information related to intention to grant a patent recorded

Free format text: ORIGINAL CODE: EPIDOSNIGR71

GRAS Grant fee paid

Free format text: ORIGINAL CODE: EPIDOSNIGR3

GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE PATENT HAS BEEN GRANTED

REG Reference to a national code

Ref country code: DE

Ref legal event code: R081

Ref document number: 602005056479

Country of ref document: DE

Owner name: CORIUM PHARMA SOLUTIONS, INC., GRAND RAPIDS, US

Free format text: FORMER OWNER: CORIUM INTERNATIONAL, INC., REDWOOD CITY, CALIF., US

Ref country code: DE

Ref legal event code: R082

Ref document number: 602005056479

Country of ref document: DE

Representative=s name: D YOUNG & CO LLP, DE

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: CORIUM, INC.

AK Designated contracting states

Kind code of ref document: B1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR

INTG Intention to grant announced

Effective date: 20191104

REG Reference to a national code

Ref country code: GB

Ref legal event code: FG4D

REG Reference to a national code

Ref country code: CH

Ref legal event code: EP

REG Reference to a national code

Ref country code: AT

Ref legal event code: REF

Ref document number: 1211579

Country of ref document: AT

Kind code of ref document: T

Effective date: 20191215

REG Reference to a national code

Ref country code: DE

Ref legal event code: R096

Ref document number: 602005056479

Country of ref document: DE

REG Reference to a national code

Ref country code: IE

Ref legal event code: FG4D

REG Reference to a national code

Ref country code: NL

Ref legal event code: FP

REG Reference to a national code

Ref country code: LT

Ref legal event code: MG4D

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20191211

Ref country code: GR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20200312

Ref country code: BG

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20200311

Ref country code: ES

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20191211

Ref country code: FI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20191211

Ref country code: SE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20191211

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: CZ

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20191211

Ref country code: PT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20200506

Ref country code: RO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20191211

Ref country code: EE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20191211

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20200411

Ref country code: SK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20191211

REG Reference to a national code

Ref country code: DE

Ref legal event code: R097

Ref document number: 602005056479

Country of ref document: DE

REG Reference to a national code

Ref country code: AT

Ref legal event code: MK05

Ref document number: 1211579

Country of ref document: AT

Kind code of ref document: T

Effective date: 20191211

PLBE No opposition filed within time limit

Free format text: ORIGINAL CODE: 0009261

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: DK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20191211

Ref country code: MC

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20191211

26N No opposition filed

Effective date: 20200914

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: AT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20191211

Ref country code: PL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20191211

Ref country code: SI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20191211

REG Reference to a national code

Ref country code: BE

Ref legal event code: MM

Effective date: 20200331

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LU

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20200324

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20200324

Ref country code: IT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20191211

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: BE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20200331

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: TR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20191211

Ref country code: CY

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20191211

REG Reference to a national code

Ref country code: DE

Ref legal event code: R081

Ref document number: 602005056479

Country of ref document: DE

Owner name: CORIUM PHARMA SOLUTIONS, INC., GRAND RAPIDS, US

Free format text: FORMER OWNER: CORIUM, INC., MENLO PARK, CA, US

REG Reference to a national code

Ref country code: GB

Ref legal event code: 732E

Free format text: REGISTERED BETWEEN 20230316 AND 20230322

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: FR

Payment date: 20230327

Year of fee payment: 19

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: GB

Payment date: 20230327

Year of fee payment: 19

Ref country code: DE

Payment date: 20230329

Year of fee payment: 19

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: NL

Payment date: 20230326

Year of fee payment: 19

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: CH

Payment date: 20230402

Year of fee payment: 19