EP1673052A1 - Recipient contenant des elements d'information a code - Google Patents

Recipient contenant des elements d'information a code

Info

Publication number
EP1673052A1
EP1673052A1 EP04762882A EP04762882A EP1673052A1 EP 1673052 A1 EP1673052 A1 EP 1673052A1 EP 04762882 A EP04762882 A EP 04762882A EP 04762882 A EP04762882 A EP 04762882A EP 1673052 A1 EP1673052 A1 EP 1673052A1
Authority
EP
European Patent Office
Prior art keywords
container
code information
information elements
container according
code
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP04762882A
Other languages
German (de)
English (en)
Inventor
Wengel Lasse Christoffersen
Preben Mikael Nielsen
Lennart Bo Erik Berggren
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Nordisk AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS
Publication of EP1673052A1 publication Critical patent/EP1673052A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/14566—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons with a replaceable reservoir for receiving a piston rod of the pump
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/06—Ampoules or carpules
    • A61J1/062—Carpules
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06K—GRAPHICAL DATA READING; PRESENTATION OF DATA; RECORD CARRIERS; HANDLING RECORD CARRIERS
    • G06K19/00—Record carriers for use with machines and with at least a part designed to carry digital markings
    • G06K19/06—Record carriers for use with machines and with at least a part designed to carry digital markings characterised by the kind of the digital marking, e.g. shape, nature, code
    • G06K19/06009—Record carriers for use with machines and with at least a part designed to carry digital markings characterised by the kind of the digital marking, e.g. shape, nature, code with optically detectable marking
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06K—GRAPHICAL DATA READING; PRESENTATION OF DATA; RECORD CARRIERS; HANDLING RECORD CARRIERS
    • G06K7/00—Methods or arrangements for sensing record carriers, e.g. for reading patterns
    • G06K7/10—Methods or arrangements for sensing record carriers, e.g. for reading patterns by electromagnetic radiation, e.g. optical sensing; by corpuscular radiation
    • G06K7/14—Methods or arrangements for sensing record carriers, e.g. for reading patterns by electromagnetic radiation, e.g. optical sensing; by corpuscular radiation using light without selection of wavelength, e.g. sensing reflected white light
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06K—GRAPHICAL DATA READING; PRESENTATION OF DATA; RECORD CARRIERS; HANDLING RECORD CARRIERS
    • G06K7/00—Methods or arrangements for sensing record carriers, e.g. for reading patterns
    • G06K7/10—Methods or arrangements for sensing record carriers, e.g. for reading patterns by electromagnetic radiation, e.g. optical sensing; by corpuscular radiation
    • G06K7/14—Methods or arrangements for sensing record carriers, e.g. for reading patterns by electromagnetic radiation, e.g. optical sensing; by corpuscular radiation using light without selection of wavelength, e.g. sensing reflected white light
    • G06K7/1404—Methods for optical code recognition
    • G06K7/146—Methods for optical code recognition the method including quality enhancement steps
    • G06K7/1491—Methods for optical code recognition the method including quality enhancement steps the method including a reconstruction step, e.g. stitching two pieces of bar code together to derive the full bar code
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J2205/00—General identification or selection means
    • A61J2205/10—Bar codes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/60—General characteristics of the apparatus with identification means
    • A61M2205/6063—Optical identification systems

Definitions

  • Container comprising code information elements
  • This invention relates to a container for a medication delivery device comprising an optical reader, where said container comprises a code information element carrying a set of informa- tion readable by said optical reader.
  • This invention further relates to a method of applying code information elements onto the container.
  • the invention relates to a method of reading a code information element.
  • containers with medication for a certain number of doses are mounted in the delivery device, e.g. a pump, a syringe, a pen injector, etc and exchanged with a new one when the container is empty, is obsolete or when another medication is to be used according to the particular situation.
  • the medication used is the intended one, that it is not too old, that it has the correct concentration, type etc. Therefore the marking of the container with the medication has to be given special attention.
  • a marking of the container in addition to a traditional alphanumeric inscription has been introduced.
  • the item of information may hold technical data on the type of container, outlet dimension or other information of relevance to the medication delivery process.
  • a user of containers may - for various medication purposes - have a set of geometrical alike containers, i.e. containers all having the same shape.
  • these containers may com- prise different medicine in various formulations, i.e. constitute a product safety problem for the user since chances of choosing a wrong container are rather high.
  • insulin it is known to be supplied in different concentrations for various purposes, such as slow acting, fast acting, mix insulin. It is therefore of great importance for the patient to select and apply only the right container for his treatment, if wrong content applied, it can cause severe problems, e.g. hyper or hypoglycaemia.
  • a readable code applied on said containers is therefore helpful in distinguishing such containers from one another, e.g. the readable code may be read from a reader inside a medica- tion delivery device in order to select and subsequently only to apply medicine from the container having the correct content.
  • Penfill ⁇ is an insertable and removable medical container into a syringe, such as pen injectors known from Novo Nordisk.
  • containers with medication are to be stored in a cool environment, e.g. in a fridge prior to use.
  • the coded information e.g. the barcode or matrix coded label, or any other printed label on the container, i.e. the labels carrying the coded information may then end up being non readable.
  • an object of the present invention is to provide a container with readable information, such as medicament type, expiry date, which improves the likelihood that the information printed on the container can be read with a high degree of security from a reader within a medication delivery device.
  • the container comprises at least one more code information element carrying the set of information readable by said optical rea- der.
  • an optical code reader - embedded in the medication delivery device - attempting to read more than one code information element will be able to read the information carried, i.e. said set of information.
  • sophisticated image processing software can compile and combine picture elements from more partly damaged code information elements, i.e. compiling and combining only picture elements undamaged, such that one single complete undamaged picture element is re-created as an image through sampling of undamaged image parts, i.e. undamaged parts of code information elements.
  • the more code information elements available - even though more or all of these are partly damaged - the more likely it is that it is possible to re-create one single complete picture element - as the perfect image - from several code information elements applied on the container.
  • the undesirable effects, arising from humidity, dirt, dirty or sweaty fingers damaging the code information elements are minimised.
  • the container carrying the coded information is to be read from or within an optical reader embedded in the medication delivery device, such as a syringe, a pump, it is a further object of the invention that the container's coded information can be securely and easily read when the container applied, i.e. the container is positioned and fixed into said medication delivery device prior to use.
  • code information elements are aligned with at least one protrusion, e.g. a tooth - or are aligned with at least one cavity on the container.
  • a cavity or more cavities present on the cartridge may match contacting surfaces, e.g. a protrusion or more protrusions present in the medical delivery device.
  • the code information elements are brought in round going alignment with one or more of the protrusions of the medical delivery device. Consequently, the optical code reader can in this embodiment be brought in alignment with one or more of the code information elements.
  • a protrusion or more protrusions present on the cartridge may match contacting surfaces, e.g. a cavity or more cavities present in the medical delivery device.
  • the code information elements are brought in round going alignment with one or more of the cavities of the medical delivery device. Consequently, the optical code reader can in this embodiment also be brought in alignment with one or more of the code information elements.
  • the optical code reader will know where the coded information, i.e. the code information elements, are applied on the container.
  • the optical code reader will then be able to read one or more code information elements when the cartridge is properly positioned towards the reader, i.e. the optical code reader will "see" one or more of the coded information elements on the cartridge.
  • the optical code reader when code information elements are juxta- posed to one another and all the way around the cartridge, thus the optical code reader will then be able to read one or more code information elements, since these will always be present for the reader regardless of the orientation of the cartridge. Consequently, the optical code reader will "see" one or more of the coded information elements on the cartridge independent of its round-going orientation in the medical delivery device code.
  • the term 'container' is taken to mean a container for holding a liquid, or a powder or combinations thereof or other matter of size, volume and weight, e.g. a drug or a medicament.
  • the container may contain medication for use with a medication delivery device or system, e.g. a syringe or a pump, for treatment or self-treatment of a disease.
  • the medication in the container may e.g. be insulin for use with a pen-type injection system for treating diabetes.
  • the container may, as exemplary embodiments, be a bottle, a bag, a cartridge, a vial or a pre-filled syringe, a blister pack, all of which are capable of containing medication in some form.
  • fig. 1 shows an unlabelled cartridge product
  • fig. 2 shows repeated code information elements applied on the cartridge
  • fig. 3 shows a label with repeated code information elements
  • fig. 3A also shows another label with repeated code information elements
  • fig. 4 shows a label with code information elements that are repeated in axial and round going direction
  • fig. 4A shows another label with code information elements that are repeated in axial and round going direction
  • fig. 5 shows a label with mutually axially displaced code information elements
  • fig. 6 shows quadratic repeated code information elements
  • fig. 7 shows an exemplary code information element
  • fig. 8 shows a cartridge where the repeated code information elements are applied on its code top; fig. 9 shows a repeated code information element applied on an endless band, fig. 10 shows a protrusion at the code top.
  • fig. 11 shows a cartridge inside a drug administration device .
  • fig. 12 shows another cartridge inside another drug administration device .
  • fig. 13 shows protrusions on the cartridge;
  • fig. 14 shows cavaties on the cartridge; and
  • fig. 15 shows requirements to a band of code information elements.
  • Figure 1 shows an unlabelled cartridge product, it comprises a glass cartridge, a plunger, a septum, a cap and a threaded code top.
  • the figure shows the unlabelled cartridge product of reference numeral 10. This is applicable in a medical delivery device, e.g. for pen injectors that contains the glass cartridge (10) with a medicament, the plunger (11 ), the septum (12), the cap (13) and the threaded code top (14).
  • the cartridge product may have one or more protrusions (15), e.g. a tooth or teeth for mechanical coding for alignment of the container in a device capable of reading one or more code information elements, i.e. said teeth or tooth can be suitable for aligning the cartridge product in a medical delivery device, e.g.
  • one or more cavities may as well be suitable for aligning the cartridge product in the delivery device, and consequently also suitable for aligning the cartridge product towards said optical reader, whereby - in both cases - the optical reader can easily and more securely read one or more code information element(s) - or parts of them - positioned relative to said teeth, tooth or cavities, since the optical reader - due to said accurately positioned code information elements on a fixed container - knows from which point(s) it has to capture images (represented in one or more code information elements).
  • the cavity - as shown on figure 14 by means of reference numeral 16 - may in principle provide the same functionality as said protrusion, as shown on figure 13 by means of reference numeral 15.
  • one or more code information elements are aligned with at least one protrusion, e.g. aligned to a tooth or teeth on the container.
  • one or more code information elements are aligned with at least one cavity on the container.
  • these (protrusion, cavity) enable easily reading of coded information on the container, since these provided means (cavity, protrusion) may be used for locating code information element(s) in the medication delivery device.
  • the optical reader embedded in the medication delivery de- vice is then able to read the coded information, since the position of code information elements) is fixed relatively to one or more cavities or protrusions on the container, when fixed in the medication delivery device.
  • a protrusion may fit into a cavity on the container, and - vice versa - in the medication delivery device a cavity may fit into a protrusion on the container, thereby - in both cases - accurately fixing the position of one or more code information elements - on the container - towards the optical reader embedded in the medication delivery device.
  • FIG. 2 shows repeated code information elements applied on the cartridge in accordance with the invention.
  • a code information element is repeated around the cartridge.
  • the repeated code information elements are applied opposite to the plunger in its storage position.
  • At least two code information elements are juxtaposed to one another. It will then be possible for an optical reader embedded in the medication delivery device to image process these elements, and - again - it is likely to combine picture elements from, in this case two eventually partly code information elements, in order to recreated an undamaged image.
  • even more code information elements can be juxtaposed to one another.
  • juxtaposed to one another all the way around the cartridge, and in this embodiment, it will to an even higher degree be possible to recreate an undamaged image from these many juxtaposed code information elements.
  • This embodiment is advantageous, since the cartridge can be positioned into the drug administration device (110) - see figures 11 and 12 - without the need to take advantage of any cavity or protrusion on the code top. This is the case, since the cartridge is provided with these many juxtaposed code information elements all the way around the cartridge.
  • the optical reader - se figures 11 and 12, reference numeral 111 - will always have one or more code information elements presented to it when the cartridge is positioned into the drug administration device, this is the case regardless of the round-going orientation of cartridge in this embodiment.
  • the coded information from one or more code information elements, can be securely and easily read (by the optical reader) when the cartridge is positioned in various ways into said drug administration device.
  • the distance between juxtaposed code information elements repeated around the cartridge may be dependent on the tolerance of the diameter of the cartridge. This is to ensure that code information elements being juxtaposed across a label are not overlapping each other due to cartridge circumpherence uncertainty.
  • the cartridge may comprise a plunger and one ore more code information elements may be applied directly opposite the plunger in its position of storage. This is an advantage, since it provides unhindered visual inspection of cartridge content.
  • the axial position of the code information elements may be defined relative to the end of the cartridge comprising the plunger in its position of storage, this is an advantage since it may minimize the field of vision required for the optical reader in both axial directions of the optical reader.
  • Figure 3 shows a label with repeated codes that can be wrapped around the cartridge.
  • the label contains a predominantly transparent part that allows visual inspection of the cartridge content.
  • the label height is larger than the cartridge circumference and therefore a lower portion of the label will be covered by an upper portion of the label.
  • Figure 3A also shows a label with repeated code information elements, however with another pattern than that of the foregoing figure.
  • Said label can also be wrapped around the cartridge.
  • the label contains a predominantly transparent part that allows visual inspection of the cartridge content.
  • the label height is larger than the cartridge circumference and therefore a lower portion of the label will be covered by an upper portion of the label.
  • Figure 4 shows a label with code information elements that are repeated in axial and round going direction.
  • Figure 4A shows a label with code information elements that are repeated in axial and round going direction.
  • a task may be to apply a label to the container; this can be automated in the following way:
  • Code information elements may in before have been applied on an endless band.
  • the endless band is arranged to be pushed over the container, and from that a part or parts of said endless band then are applied onto the container.
  • Figure 5 shows a label where mutually axially displaced code information elements are also mutually repeated by half the repetition distance around the cartridge.
  • code information elements can be juxtaposed to one another.
  • code information elements can be juxtaposed to one another all the way around the cartridge, and in this embodiment, it will to a high degree be possible to recreate an undamaged image from these many juxtaposed code information elements.
  • said rotation corresponds to half the repetition distance around the container.
  • 1 - 100 further code information elements are applied on the container - eventually be means of one ore more labels carrying them, thus to a high degree of certainty an undamaged image can be created.
  • 2 - 20 further code information elements are applied on the container - eventually also by means of even more labels carrying them, thus to a high degree of certainty an undamaged image can be created.
  • 3 - 30 further code information elements are applied on the container - by means of several labels carrying them, thus again to a high degree of certainty an undamaged image can be created.
  • said label - where discussed and shown in the foregoing drawings - is that it can be wrapped around the container. This enables for an easy, secure "printing" of code information elements onto the container.
  • the label with code information elements may be applied on the surface of the container, e.g. on the outer surface of it, in that case the code information element are printed on the label.
  • code information elements may be applied directly on any of the surfaces of the container, preferable on the outer surface of it to enhance readability.
  • Information in each of the code information elements may be laser engraved to resist wear.
  • said label may integral with another label for carrying readable information, i.e. for carrying code information elements.
  • the said another label may be transparent to ease visibility to the medicament in the con- tainer.
  • Figure 6 shows quadratic repeated code information elements (20).
  • Figure 7 shows an exemplary code information element.
  • a code information element may comprise pixels.
  • the code information element shown here comprises a Data Matrix code. This is known to comprise redundant data, thus it enables a subsequent error correction, e.g. by use of error correction algorithms.
  • the data i.e. the set of information in code information element may represent at least a medicament type, further it may represent an expiry date, and or a batch number.
  • the set of information may also comprise a string of characters representing a manufacturer of the container's content, e.g. Novo Nordisk, an affiliate company, etc.
  • the set of information may also comprise a string of characters representing a manufacturer of the container.
  • an optical reader of the drug administration device can read the image representing the set of information on the container, and subsequently the set of information on the con- tainer can be decoded and interpreted.
  • the device can then check whether the drug, i.e. the read medicament type, is allowed to be supplied, i.e. injected in a proper dose and in a proper concentration from the read manufacturer, provided that the read expiry date is not exceed.
  • Said batch number may be used for tracing sold products, for quality control, etc, it may even be used for withdrawal of products, e.g. withdrawals of sold containers bearing a specific batch number series.
  • code information elements are to be read, it is advantageous that a surface of an information-carrying area of each of said code information elements is treated to enhance optical reading. The treatment thereby enhances reading of said set of information.
  • the treatment may comprise use of a transparent printing ink with dispersed transparent particles.
  • each of said particles may as - an exemplary embodiment - be approximately 5- 10 times smaller than a size of pixels in each of the code information elements.
  • Figure 8 shows a cartridge where the repeated code information elements are applied onto the code top. It can be seen that a tooth (15) at the code top (14) can be used to align one or more the repeated code information elements against an optical reader.
  • one single protrusion e.g. a tooth on the container may be used to align code information elements when applied on the container.
  • one single cavity may be used to align code information elements on the container.
  • Figure 9 shows a repeated code information element applied on an endless band that can be arranged to be pushed over a container.
  • Figure 10 shows a protrusion, e.g. teeth (15) at the code top (14) - which as discussed in the foregoing figures may be used to align one ore more repeated code information elements.
  • the repeated code information are aligned to a tooth (15) - e.g. at the code top (14) as shown in figure 8 - or as shown in the figure to align code information elements on the surface anywhere on the container.
  • a cavity (16) at the code top as shown in figure 14 may be used as a fix point, i.e. the cavity may be used to align code information elements, e.g. at the code top (14) as shown in figure 8.
  • Figure 11 shows a cartridge inside a medical delivery device (110).
  • An optical code reader (111 ) placed inside the device enables reading of the code information elements.
  • the optical code reader comprises an image sensor, a lens, an aperture and a contacting surface.
  • One or more protrusions present at the cartridge match contacting surfaces in the medical deliv- ery device. Springs in the device facilitate that the corresponding medical device and cartridge contacting surfaces meet.
  • the contacting surfaces enable alignment of the code information elements and the optical code reader along the axial and radial direction of the cartridge cylinder. Furthermore, if the code information elements are brought in round-going alignment with one or more of the protrusions, then the optical code reader can be brought in round going alignment with the code information elements.
  • a cavity or more cavities present on the cartridge may match contacting surfaces, e.g. a protrusion or more protrusions present in the medical delivery device.
  • the code information elements are brought in round going alignment with one or more of the protrusions of the medical delivery device. Consequently, the optical code reader can in this embodiment be brought in alignment with one or more of the code information elements.
  • a protrusion or more protrusions present on the cartridge may match contacting surfaces, e.g. a cavity or more cavities present in the medical delivery device.
  • the code information elements are brought in round going alignment with one or more of the cavities of the medical delivery device. Consequently, the optical code reader can in this embodiment also be brought in alignment with one or more of the code information elements.
  • the optical code reader will know where the coded information is applied on the container.
  • code information elements when code information elements are juxtaposed to one another and all the way around the cartridge, e.g. the cartridge as shown in figure 8, neither a cavity nor a protrusion is necessary for alignment of this cartridge, when placed into the shown medical delivery device.
  • the optical code reader (111 ) will be able to read one or more code information elements, since it or these will be present for the reader regardless of the orientation of the cartridge. Consequently, one or more of the coded information elements will be imaged on the optical code reader independent of the cartridge's round-going orientation in the medical delivery device code
  • the optical reader of use may have a field of vi- sion that is so comprehensive that it is able to accommodate significantly more than one single code information element.
  • an image sensor may be used together with optics for presenting one single code information element and at least one fraction of a neighbouring code information element on the optical reader.
  • Figure 12 is another embodiment of another medical delivery device (110) where a contacting surface at the optical code reader meets the cartridge base.
  • the optical code reader is associated to the device shell by means of a flexible beam that acts as a spring that forces the optical code reader towards the cartridge base in the axial direction.
  • Figure 13 shows protrusions (15) on the cartridge as well as the part of the device shell that is brought in contact with the cartridge. Cross sections along axial and radial axes are shown.
  • Figure 14 shows cavities (16) in the cartridge as well as the part of the device shell that is brought in contact with the cartridge.
  • Figure 15 shows requirements to a band of code information elements.
  • the geometry of the band of code information elements is considered.
  • the band geometry must ensure that at least one whole code information element symbol is imaged regardless of the rotation along the cylinder axis of the cartridge. Also, at least one whole code information element symbol must be imaged when the overall tolerances of the system are taken into consideration.
  • Important quantities are defined in the table.
  • the quantities LJT and QZ2 are defined in figure 15.
  • N can be chosen to make N equal to Nmax to minimise WOD, or to decrease N and thereby increase QZ1 and decrease the risk of label joint failures.
  • the height of object to be depicted is related to the symbol height and label x-tolerance by
  • DIV (1.6+0.5) 16
  • the distance between juxtaposed code information elements repeated around the container is therefore dependent on the tolerance of the diameter of the container as discussed above. This enables for that a number of code information elements, (N) can be computed to a predetermined number and also to a predetermined distance between two juxtaposed code information elements as shown in the formulas above. The predetermined distance the applied between every two juxtaposed code information elements.
  • CMOS sensor In order to capture the image from the cartridge a CMOS sensor may be the choice of use.
  • the CMOS sensor has the advantage compared to CCD sensors of being small and cheap, and since it has a low power consumption. Furthermore, it is easy to use and do not require use of external components like clock and analogue to digital converters.
  • the image sensor does not have to be a colour image sensor.
  • the area of the captured image which is of interest, may be twice the size of the DM plus 2 times the area between two DM. That the criterion is a minimum of 2 pixels per symbol pixel, the CMOS must be able to represent (2 • 8 + 4) • 2 pixels horizontally and (18 + 4) - 2 vertically, giving 40 - 44 pixels in all. More pixels mean more information in the image and the market conditions for CMOS sensors is limited for CMOS sensors with low numbers of pixels.
  • the typical CMOS sensors available on the market have reduced resolution compared to the CCD sensor, which is used in applications as web cams, mobile telephones, and small digital cameras with resolutions less than 2Mpix. Many of the smaller CMOS sensors available have a pixel resolution of 640x320 (VGA), 320x200 or QCIF 160x128 pixels, which is slightly more than necessary as compared to the present invention disclosed herein.
  • the image sensor may be the LM9630 from National Semiconductors.
  • the number of pixels is 101x128, it has high light sensitivity and a maximum frame rate of 580 frames per second (Fps).
  • the high frame rate is not necessary for this application, nor is the high light sensitivity.
  • the sampling period may have to be equal to or smaller than one-half of the period of the finest detail.
  • the resolution of an image sensor must have a resolution high enough so that the image through the optical lens will have more than 2 samples per pixel, i.e. Nyquist criterion.
  • the code information element is a DM, which has 8 symbols vertically and 18 horizontally (144 symbol pixels), which means that for the chosen image sensor, the lens could have an enlargement less than 101/8 or 128/18, which is about 7 times. Otherwise there may be a risk that the image cannot be reconstructed, i.e. the image is under-sampled.
  • the DM image can theoretically be reconstructed if it has more than 16x36 pixels. A doubling of the pixels increase the calculation time, but also enhances the chance of obtaining a correct DM symbol, since there are more pixels to work with.
  • the lens used is mounted in a camera house, but the positioning of the lens could not be tested during the manual process of gluing, which resulted in lenses that did not have the optical axis in the centre of the image.
  • the code information element e.g. the DM is printed in a white area on the label.
  • the DM must be situated in the centre of the white area, and the white area must be so wide, that the white band (also in worst case conditions) is the background of the DM.
  • DM is a 2D matrix code invented by RVSI Acuity CiMatrix, a subsidiary of Robotic Vision Systems, Inc., and placed in the public domain.
  • DM is designed for a high code density and employs RS error correction with data redundancy to ensure reliability.
  • a DM symbol can store between one and 3116 numeric or 2335 alphanumeric characters. While DM is scal- able between 1-mil square to a 14-inch square, the actual limits are dependent on the fidelity of the marking device and the optics of the reader.
  • 2D codes or symbologies exist, apart from DM and as alternatives to DM, i.e. Data Matrix.
  • Some alternatives are stacked codes, like PDF417, and some alternatives are matrix codes.
  • Stacked codes can best be described as having two or more rows of one- dimensional barcodes and so also possess a direction - first row, second row , while matrix codes are non-directional.
  • a non-comprehensive list of available matrix codes includes Data Glyphs, Aztech Code, Code 1 , CP Code, MaxiCode, QR Code, Snowflake code and Ulta- code.
  • Most widely used 2D codes contain indicia that ease the determination of size, position and angular orientation of the imaged code.
  • the mentioned quantities are often required for extracting the information from the code.
  • Datamatrix codes have two solid perimeter lines that constitute an L shape. The L shape can easily be located by known ma- chine vision algorithms, such as gradient or threshold based edge finder algorithms. Thereby the L shape allows determination of the
  • repeated information code elements may be applied on the container in various ways, such as mutually separated patterns, as a coherent pattern and/or as partly coherent patterns.
  • Additional information such as non-repeated information, may be applied on the container in combination with the invention of applied repeated code information elements.
  • the additional information can be coherent to the repeated code information elements.
  • any of the repeated code information elements can be constituted by a first code information element containing a first set of information, combined with a second code information element containing a second set of information from which the first set of information can be extracted by means of a predetermined data transformation algorithm.
  • the data transformation algorithm can for example be reducing the amount of information in the second set of information to fit the first set of information.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Theoretical Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Artificial Intelligence (AREA)
  • Toxicology (AREA)
  • Electromagnetism (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Quality & Reliability (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Details Of Rigid Or Semi-Rigid Containers (AREA)

Abstract

L'invention concerne un récipient (10) pour un dispositif de libération de médicament (110) comprenant un lecteur optique (111). Ce récipient comprend un élément d'information à code (20) comportant un ensemble d'informations lisibles par ledit lecteur optique. Ce récipient se caractérise en ce qu'il comprend au moins un élément d'information à code (20) comportant l'ensemble d'informations lisibles par ledit lecteur optique. L'invention porte également sur un procédé d'application d'éléments d'information à code sur le récipient et sur un procédé de lecture d'un élément d'information à code. Ces éléments d'information à code peuvent être alignés avec au moins une saillie se trouvant sur le récipient ou sont alignés avec au moins une cavité se trouvant sur le récipient.
EP04762882A 2003-10-03 2004-09-30 Recipient contenant des elements d'information a code Withdrawn EP1673052A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DKPA200301457 2003-10-03
US51045303P 2003-10-10 2003-10-10
DKPA200301560 2003-10-23
US51658903P 2003-10-31 2003-10-31
PCT/DK2004/000662 WO2005032449A1 (fr) 2003-10-03 2004-09-30 Recipient contenant des elements d'information a code

Publications (1)

Publication Number Publication Date
EP1673052A1 true EP1673052A1 (fr) 2006-06-28

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EP04762882A Withdrawn EP1673052A1 (fr) 2003-10-03 2004-09-30 Recipient contenant des elements d'information a code

Country Status (7)

Country Link
EP (1) EP1673052A1 (fr)
JP (1) JP2007507260A (fr)
KR (1) KR20060102550A (fr)
AU (1) AU2004277306A1 (fr)
CA (1) CA2540715A1 (fr)
IL (1) IL174543A0 (fr)
WO (1) WO2005032449A1 (fr)

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WO2007122473A1 (fr) * 2006-04-20 2007-11-01 Ares Trading Sa Procede de marquage destine a des articles pharmaceutiques
US8052645B2 (en) 2008-07-23 2011-11-08 Avant Medical Corp. System and method for an injection using a syringe needle
AU2009249027C1 (en) 2008-05-20 2015-01-22 Avant Medical Corp. Autoinjector system
MY152436A (en) * 2008-10-13 2014-09-30 Sanofi Aventis Deutschland Drug delivery device and method of manufacturing a drug delivery device
US8181849B2 (en) 2008-12-30 2012-05-22 Medtronic Minimed, Inc. Color detection system for detecting reservoir presence and content in device
US20100168711A1 (en) 2008-12-30 2010-07-01 Medtronic Minimed, Inc. Color detection system for detecting reservoir presence and content in device
US20120101470A1 (en) 2009-02-13 2012-04-26 Novo Nordisk A/S Medical device and cartridge
EP2449505B1 (fr) 2009-06-30 2015-06-17 Sanofi-Aventis Deutschland GmbH Code-barres circulaire pour réservoir de médicaments
CA2796742A1 (fr) * 2010-04-23 2011-10-27 Sanofi-Aventis Deutschland Gmbh Virole codee pour dispositif d'administration de medicament
HUE024418T2 (en) 2010-04-30 2016-01-28 Becton Dickinson France Procedure for marking a transparent container
WO2012020088A2 (fr) * 2010-08-13 2012-02-16 Sanofi-Aventis Deutschland Gmbh Ensemble cartouche codé
CA2808469A1 (fr) * 2010-08-19 2012-02-23 Sanofi-Aventis Deutschland Gmbh Procede et systeme pour determiner des informations concernant un reservoir de medicament utilisant un capteur electronique
CA3145238A1 (fr) 2011-04-20 2012-10-26 Amgen Inc. Appareil auto-injecteur
US9563790B2 (en) 2011-08-03 2017-02-07 Panasonic Healthcare Holdings Co., Ltd. Information recording medium, columnar body having information recording medium affixed thereto, information reading device therefor, pharmaceutical injection device using this information reading device, information reading method, and non-transitory computer readable medium
USD898908S1 (en) 2012-04-20 2020-10-13 Amgen Inc. Pharmaceutical product cassette for an injection device
FR2990136B1 (fr) * 2012-05-02 2015-06-19 Pharmadyne Kit de recharge d'une pompe a perfusion, methode de preparation et d'utilisation de celui-ci
WO2014143815A2 (fr) 2013-03-15 2014-09-18 Amgen Inc. Boîte à médicament, autoinjecteur et système d'autoinjecteur
US10546172B2 (en) 2015-03-30 2020-01-28 Temptime Corporation Two dimensional barcode with dynamic environmental data system, method, and apparatus
US10318781B2 (en) * 2015-03-30 2019-06-11 Temptime Corporation Two dimensional barcode with dynamic environmental data system, method, and apparatus
GB201805268D0 (en) 2018-03-29 2018-05-16 Nicoventures Trading Ltd Apaaratus for generating aerosol from an aerosolisable medium, an article of aerosolisable medium and a method of operating an aerosol generating apparatus
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US6110152A (en) * 1998-01-13 2000-08-29 Minimed Inc. Medication cartridge for an electronic pen-type injector, infusion pump, electronic delivery device, or the like, and method of making the same
JP2000272191A (ja) * 1999-03-23 2000-10-03 Nec Eng Ltd 物品識別方法
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Also Published As

Publication number Publication date
IL174543A0 (en) 2006-08-01
JP2007507260A (ja) 2007-03-29
KR20060102550A (ko) 2006-09-27
AU2004277306A1 (en) 2005-04-14
WO2005032449A1 (fr) 2005-04-14
CA2540715A1 (fr) 2005-04-14

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