EP1663137A1 - A preparation for use against flying insects that bite - Google Patents

A preparation for use against flying insects that bite

Info

Publication number
EP1663137A1
EP1663137A1 EP04768102A EP04768102A EP1663137A1 EP 1663137 A1 EP1663137 A1 EP 1663137A1 EP 04768102 A EP04768102 A EP 04768102A EP 04768102 A EP04768102 A EP 04768102A EP 1663137 A1 EP1663137 A1 EP 1663137A1
Authority
EP
European Patent Office
Prior art keywords
preparation
oil
flying insects
bite
allantoin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP04768102A
Other languages
German (de)
French (fr)
Inventor
Donald Henry Yates
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP1663137A1 publication Critical patent/EP1663137A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/31—Hydrocarbons
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/10—Aromatic or araliphatic carboxylic acids, or thio analogues thereof; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/18—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N<, e.g. carboxylic acid amides or imides; Thio analogues thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N61/00—Biocides, pest repellants or attractants, or plant growth regulators containing substances of unknown or undetermined composition, e.g. substances characterised only by the mode of action
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/27—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42—Amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/02—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings containing insect repellants

Definitions

  • This invention relates to a preparation for use against flying insects that bite.
  • the flying insects are typically midges, mosquitoes and other biting, blood-sucking insects. Flying insects such for example as midges and mosquitoes cause much misery to animals and human beings. The flying insects tend to attack in summer and autumn months and their bites cause irritation such for example as itching and stinging.
  • There are several known preparations for use against the flying insects but these known preparations are not sufficiently effective. For example, some of the known preparations concentrate simply on repelling attacks by the flying insects, while others of the known preparations concentrate simply on soothing and relieving pain from the bites. It is an aim of the present invention to reduce the above mentioned problem.
  • a preparation for use against flying insects that bite which preparation comprises: i) benzyl benzoate; ii) diethyl toluamide; iii) zinc carbonate; iv) zinc oxide; v) allantoin; and vi) petrolatum.
  • the preparation of the present invention is advantageous in that it first of all acts to deter the flying insects from biting, and it secondly acts to alleviate irritation if the flying insects do actually bite.
  • the preparation of the present invention is especially advantageous for use on animals such for example as horses and ponies, but it may be used on other animals that tend to suffer from attacks from the fly insects.
  • the preparation may also advantageously be used on human beings.
  • the preparation of the present invention can advantageously include: vii) tea tree oil; and/or viii) peppermint oil.
  • the preparation comprises: i) 1 - 35% benzyl benzoate; ii) 1 - 30% diethyl toluamide; iii) 0.5 - 25% zinc carbonate; iv) 0.5 - 40% zinc oxide; v) 0.1 - 5% allantoin; vi) 5 - 95% petrolatum; vii) 0.0 - 5% tea tree oil; and viii) 0.0 - 10% peppermint oil. As used herein, all percentages are by weight.
  • the preparation preferably comprises: i) 20.0% benzyl benzoate; ii) 5.0% diethyl toluamide; iii) 4.0% zinc carbonate; iv) 2.0% zinc oxide; v) 0.2% allantoin; vi) 63.4% petrolatum; vii) 0.2% tea tree oil; and viii) 0.2% peppermint oil, the balance to 100% being made up of at least one other ingredient.
  • the zinc carbonate in the preparation may be present as calamine.
  • the preparation includes white oil.
  • the white oil is an emollient/moisturiser but its main function in the preparation of the invention is to control viscosity and to assist in ease of use.
  • the white oil is presently present in an amount of 5 - 95%. In the above mentioned preferred formulation of the invention, the white oil is preferably present in an amount of 5%, in order to give a total of 100%.
  • the allantoin may be complemented or assisted by panthenol and/or biotin.
  • the tea tree oil and/or the peppermint oil may be complemented or assisted by one or more of aloe vera, calendula, thymol, citronella, manuka honey, evening primrose oil, yarrow and neem oil.
  • the diethyl toluamide may be complemented or assisted by a pyrethroid
  • the preparation of the present invention is preferably in the form of a cream, paste or salve. The preparation may be in other forms if desired, for example as a liquid. Reference will now be made to the following Examples.
  • a preparation was formulated comprising the following ingredients: i) 20.0% benzyl benzoate; ii) 5.0% diethyl toluamide; iii) 4.0% zinc carbonate; iv) 2.0 % zinc oxide; v) 0.2% allantoin; vi) 63.4% petrolatum; vii) 0.2% tea tree oil; viii) 0.2% peppermint oil; and ix) 5.0% white oil.
  • the above preparation was formulated by mixing the ingredients together at room temperature.
  • the zinc carbonate was present as calamine.
  • the preparation was made in the form of a salve. Some horses in a field were divided into two groups. The first group was treated with the salve. The second group was not treated with the salve.
  • irritation such for example as stinging and itching appeared to be considerably less than occurred for those horses that were bitten in the second group.
  • the irritation resulting from the bites often results in rubbing that causes the horses to lose their hair in the area suffering the irritation.
  • the preparation of the present invention assisted in hair re-growth due to the inclusion in the preparation of the allantoin which is a keratolytic agent.
  • Example II A similar test as above for Example I was carried out on some ponies. The ponies were divided into two groups and substantially the same results were achieved as for the horses mentioned in Example I. It is to be appreciated that the Examples given above have been given by way of illustration only and that modifications may be effected.
  • the preparation is effective against flying insects other than midges and mosquitoes.
  • the preparation may be effective against midges, mosquitoes, black flies, knats, horse flies and other similar insects of the type that bite and suck blood.
  • the white oil may be removed or replaced by another ingredient having the same effect.

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Agronomy & Crop Science (AREA)
  • Environmental Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)

Abstract

A preparation for use against flying insects that bite, which preparation comprises: i) benzyl benzoate; ii) diethyl toluamide; iii) zinc carbonate; iv) zinc oxide; v) allantoin; and vi) petrolatum. The preparation of the present invention is advantageous in that it first of all acts to deter the flying insects from biting, and it secondly acts to alleviate irritation if the flying insects to actually bite. The preparation may include tee tree oil and/or peppermint oil.

Description

A PREPARATION FOR USE AGAINST FLYING INSECTS THAT BITE
This invention relates to a preparation for use against flying insects that bite. The flying insects are typically midges, mosquitoes and other biting, blood-sucking insects. Flying insects such for example as midges and mosquitoes cause much misery to animals and human beings. The flying insects tend to attack in summer and autumn months and their bites cause irritation such for example as itching and stinging. There are several known preparations for use against the flying insects but these known preparations are not sufficiently effective. For example, some of the known preparations concentrate simply on repelling attacks by the flying insects, while others of the known preparations concentrate simply on soothing and relieving pain from the bites. It is an aim of the present invention to reduce the above mentioned problem. Accordingly, in one non-limiting embodiment of the present invention there is provided a preparation for use against flying insects that bite, which preparation comprises: i) benzyl benzoate; ii) diethyl toluamide; iii) zinc carbonate; iv) zinc oxide; v) allantoin; and vi) petrolatum.
The preparation of the present invention is advantageous in that it first of all acts to deter the flying insects from biting, and it secondly acts to alleviate irritation if the flying insects do actually bite. The preparation of the present invention is especially advantageous for use on animals such for example as horses and ponies, but it may be used on other animals that tend to suffer from attacks from the fly insects. The preparation may also advantageously be used on human beings.
The preparation of the present invention can advantageously include: vii) tea tree oil; and/or viii) peppermint oil.
Preferably, the preparation comprises: i) 1 - 35% benzyl benzoate; ii) 1 - 30% diethyl toluamide; iii) 0.5 - 25% zinc carbonate; iv) 0.5 - 40% zinc oxide; v) 0.1 - 5% allantoin; vi) 5 - 95% petrolatum; vii) 0.0 - 5% tea tree oil; and viii) 0.0 - 10% peppermint oil. As used herein, all percentages are by weight. The preparation preferably comprises: i) 20.0% benzyl benzoate; ii) 5.0% diethyl toluamide; iii) 4.0% zinc carbonate; iv) 2.0% zinc oxide; v) 0.2% allantoin; vi) 63.4% petrolatum; vii) 0.2% tea tree oil; and viii) 0.2% peppermint oil, the balance to 100% being made up of at least one other ingredient. The zinc carbonate in the preparation may be present as calamine. Preferably, the preparation includes white oil. The white oil is an emollient/moisturiser but its main function in the preparation of the invention is to control viscosity and to assist in ease of use. The white oil is presently present in an amount of 5 - 95%. In the above mentioned preferred formulation of the invention, the white oil is preferably present in an amount of 5%, in order to give a total of 100%. The allantoin may be complemented or assisted by panthenol and/or biotin. The tea tree oil and/or the peppermint oil may be complemented or assisted by one or more of aloe vera, calendula, thymol, citronella, manuka honey, evening primrose oil, yarrow and neem oil. The diethyl toluamide may be complemented or assisted by a pyrethroid The preparation of the present invention is preferably in the form of a cream, paste or salve. The preparation may be in other forms if desired, for example as a liquid. Reference will now be made to the following Examples.
EXAMPLE I A preparation was formulated comprising the following ingredients: i) 20.0% benzyl benzoate; ii) 5.0% diethyl toluamide; iii) 4.0% zinc carbonate; iv) 2.0 % zinc oxide; v) 0.2% allantoin; vi) 63.4% petrolatum; vii) 0.2% tea tree oil; viii) 0.2% peppermint oil; and ix) 5.0% white oil. The above preparation was formulated by mixing the ingredients together at room temperature. The zinc carbonate was present as calamine. The preparation was made in the form of a salve. Some horses in a field were divided into two groups. The first group was treated with the salve. The second group was not treated with the salve. The group that was treated with the salve suffered considerably less bites from flying insects such for example as midges and mosquitoes than the group that was not treated with the salve. Where the horses in the first group were bitten, then irritation such for example as stinging and itching appeared to be considerably less than occurred for those horses that were bitten in the second group. This observation was made because it was noticed that the horses in the first group appeared to be rubbing their manes, tails and other body parts considerably less than those horses that were bitten in the second group. The irritation resulting from the bites often results in rubbing that causes the horses to lose their hair in the area suffering the irritation. The preparation of the present invention assisted in hair re-growth due to the inclusion in the preparation of the allantoin which is a keratolytic agent. Where the hair was destroyed as a result of rubbing following a bite by an insect, it was noted that hair regrowth commenced quickly due to the speedy alleviation of the irritation in the bitten area, and therefore the removal of the need to rub that particular area. EXAMPLE II
A similar test as above for Example I was carried out on some ponies. The ponies were divided into two groups and substantially the same results were achieved as for the horses mentioned in Example I. It is to be appreciated that the Examples given above have been given by way of illustration only and that modifications may be effected. Thus, for example, the preparation is effective against flying insects other than midges and mosquitoes. Generally, the preparation may be effective against midges, mosquitoes, black flies, knats, horse flies and other similar insects of the type that bite and suck blood. The white oil may be removed or replaced by another ingredient having the same effect.

Claims

1. A preparation for use against flying insects that bite, which preparation comprises: i) benzyl benzoate; ii) diethyl toluamide; iii) zinc carbonate; iv) zinc oxide; v) allantoin; and vi) petrolatum.
2. A preparation to claim 1 and including: vii) tee tree oil.
3. A preparation to claim 1 or claim 2 and including: viii) peppermint oil.
4. A preparation according to claim 1 in which the preparation comprises: i) 1 - 35% benzyl benzoate; ii) 1 - 30% diethyl toluamide; iii) 0.5 - 25% zinc carbonate; iv) 0.5 - 40% zinc oxide; v) 0.1 - 5% allantoin; vi) 5 - 95% petrolatum; vii) 0.0 - 5% tea tree oil; and viii) 0.0 - 10% peppermint oil.
5. A preparation according to claim 4 in which the preparation comprises: i) 20.0% benzyl benzoate; ϋ) 5.0% diethyl toluamide; iϋ) 4.0% zinc carbonate; iv) 2.0% zinc oxide; v) 0.2% allantoin; vi) 63.4% petrolatum; vii) 0.2% tee tree oil; and viii) 0.2% peppermint oil, the balance to 100% being made up of at least one other ingredient.
6. A preparation according to any one of the preceding claims in which the preparation includes white oil.
7. A preparation according to claim 6 in which the white oil is present in an amount of 5 - 95%.
8. A preparation according to claims 5 and 7 in which the white oil is present in an amount of 5.0% to give a total of 100%.
9. A preparation according to any one of the preceding claims and in the form of a cream, paste or salve.
EP04768102A 2003-08-29 2004-08-18 A preparation for use against flying insects that bite Withdrawn EP1663137A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0320351.0A GB0320351D0 (en) 2003-08-29 2003-08-29 A preparation against flying insects that bite
PCT/GB2004/003542 WO2005020947A1 (en) 2003-08-29 2004-08-18 A preparation for use against flying insects that bite

Publications (1)

Publication Number Publication Date
EP1663137A1 true EP1663137A1 (en) 2006-06-07

Family

ID=28686628

Family Applications (1)

Application Number Title Priority Date Filing Date
EP04768102A Withdrawn EP1663137A1 (en) 2003-08-29 2004-08-18 A preparation for use against flying insects that bite

Country Status (3)

Country Link
EP (1) EP1663137A1 (en)
GB (2) GB0320351D0 (en)
WO (1) WO2005020947A1 (en)

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Publication number Priority date Publication date Assignee Title
US20030068375A1 (en) 2001-08-06 2003-04-10 Curtis Wright Pharmaceutical formulation containing gelling agent
ES2276604B1 (en) * 2005-08-18 2008-06-01 Francisco Caballero Gobern COMPOSITION FOR VETERINARY USE.
AU2012320093B2 (en) * 2011-10-04 2017-07-13 0903608 B.C. Ltd. Pest control formulations and methods of making and using same
US9999218B2 (en) 2011-10-04 2018-06-19 0903608 B.C. Ltd. Pest control formulations and methods of making and using same
HUE065596T2 (en) * 2011-10-17 2024-06-28 Univ California Methods for evaluating the repellency of organic materials and methods and compositions for the deterrence of arthropods
EP3409115A3 (en) 2013-03-15 2019-02-27 The Regents of The University of California Methods for identifying arthropod repellents, and compounds and compositions identified by such methods
AU2014349701B2 (en) 2013-11-18 2018-07-19 0903608 B.C. Ltd. Compositions, devices and methods for control of pests using vapor activity
EP3270692A4 (en) 2015-03-18 2019-02-13 The Regents of the University of California ANTI-ARTHROPOD CHEMICALS
EP4075974A1 (en) * 2019-12-17 2022-10-26 Maia Africa Sas Long protection mosquito repellent ointment

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Also Published As

Publication number Publication date
WO2005020947A1 (en) 2005-03-10
GB2405340B (en) 2007-03-28
GB2405340A (en) 2005-03-02
GB0320351D0 (en) 2003-10-01
GB0413351D0 (en) 2004-07-21

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