EP1631300A4 - Hochmolekulare polymere, vorrichtungen und verfahren zur herstellung und verwendung - Google Patents

Hochmolekulare polymere, vorrichtungen und verfahren zur herstellung und verwendung

Info

Publication number
EP1631300A4
EP1631300A4 EP04816742A EP04816742A EP1631300A4 EP 1631300 A4 EP1631300 A4 EP 1631300A4 EP 04816742 A EP04816742 A EP 04816742A EP 04816742 A EP04816742 A EP 04816742A EP 1631300 A4 EP1631300 A4 EP 1631300A4
Authority
EP
European Patent Office
Prior art keywords
production
devices
molecular weight
high molecular
weight polymers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP04816742A
Other languages
English (en)
French (fr)
Other versions
EP1631300A2 (de
Inventor
Anthony East
Alan Letton
Suseela Kanamathareddy
Bryant J Pudil
Stephen Goodrich
Michael B Hicks
Karen J Giroux
Yun Choe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
POLYMERIX Corp
Original Assignee
POLYMERIX Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by POLYMERIX Corp filed Critical POLYMERIX Corp
Publication of EP1631300A2 publication Critical patent/EP1631300A2/de
Publication of EP1631300A4 publication Critical patent/EP1631300A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/55—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being also a pharmacologically or therapeutically active agent, i.e. the entire conjugate being a codrug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/593—Polyesters, e.g. PLGA or polylactide-co-glycolide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/21—Acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/41—Anti-inflammatory agents, e.g. NSAIDs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602—Type of release, e.g. controlled, sustained, slow
    • A61L2300/604—Biodegradation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Medicinal Preparation (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Polyesters Or Polycarbonates (AREA)
EP04816742A 2003-06-04 2004-06-04 Hochmolekulare polymere, vorrichtungen und verfahren zur herstellung und verwendung Withdrawn EP1631300A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US47576603P 2003-06-04 2003-06-04
US82343504A 2004-04-12 2004-04-12
PCT/US2004/017916 WO2005042600A2 (en) 2003-06-04 2004-06-04 High molecular weight polymers, devices and method for making and using same

Publications (2)

Publication Number Publication Date
EP1631300A2 EP1631300A2 (de) 2006-03-08
EP1631300A4 true EP1631300A4 (de) 2011-03-09

Family

ID=34555535

Family Applications (1)

Application Number Title Priority Date Filing Date
EP04816742A Withdrawn EP1631300A4 (de) 2003-06-04 2004-06-04 Hochmolekulare polymere, vorrichtungen und verfahren zur herstellung und verwendung

Country Status (3)

Country Link
EP (1) EP1631300A4 (de)
CA (1) CA2527495A1 (de)
WO (1) WO2005042600A2 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7985415B2 (en) 1997-09-10 2011-07-26 Rutgers, The State University Of New Jersey Medical devices employing novel polymers
EP1309354A2 (de) 2000-07-27 2003-05-14 Rutgers, The State University Therapeutische polyester und polyamide
US9114198B2 (en) 2003-11-19 2015-08-25 Advanced Cardiovascular Systems, Inc. Biologically beneficial coatings for implantable devices containing fluorinated polymers and methods for fabricating the same
GB0327310D0 (en) 2003-11-24 2003-12-24 Oztech Pty Ltd Pressure impulse mitigation
US7435788B2 (en) 2003-12-19 2008-10-14 Advanced Cardiovascular Systems, Inc. Biobeneficial polyamide/polyethylene glycol polymers for use with drug eluting stents
US20050288481A1 (en) 2004-04-30 2005-12-29 Desnoyer Jessica R Design of poly(ester amides) for the control of agent-release from polymeric compositions
US7820732B2 (en) * 2004-04-30 2010-10-26 Advanced Cardiovascular Systems, Inc. Methods for modulating thermal and mechanical properties of coatings on implantable devices
US7166680B2 (en) 2004-10-06 2007-01-23 Advanced Cardiovascular Systems, Inc. Blends of poly(ester amide) polymers
WO2006127667A1 (en) 2005-05-23 2006-11-30 Rutgers, The State University Of New Jersey Fast degrading polymers
US8282971B2 (en) 2005-08-22 2012-10-09 Kraft Foods Global Brands Llc Degradable chewing gum
US8263143B2 (en) 2005-08-22 2012-09-11 Kraft Foods Global Brands Llc Degradable chewing gum
US8287928B2 (en) 2005-08-22 2012-10-16 Kraft Foods Global Brands Llc Degradable chewing gum
US7910152B2 (en) 2006-02-28 2011-03-22 Advanced Cardiovascular Systems, Inc. Poly(ester amide)-based drug delivery systems with controlled release rate and morphology
US20070225472A1 (en) 2006-03-23 2007-09-27 Varshney Sunil K Polyanhydride polymers and their uses in biomedical devices
EP2032614A2 (de) 2006-06-06 2009-03-11 Rutgers, The State University Of New Jersey Jodhaltige polymere
WO2008034019A2 (en) 2006-09-13 2008-03-20 Polymerix Corporation Active agents and their oligomers and polymers
WO2008051565A2 (en) * 2006-10-23 2008-05-02 Bioabsorbable Therapeutics, Inc. A drug-release composition having a therapeutic carrier
WO2008128193A1 (en) 2007-04-12 2008-10-23 Rutgers, The State University Of New Jersey Biodegradable polyanhydrides with natural bioactive molecules
US9144579B2 (en) 2012-08-17 2015-09-29 Rutgers, The State University Of New Jersey Polyesters and methods of use thereof
US20140120057A1 (en) 2012-10-25 2014-05-01 Rutgers, The State University Of New Jersey Polymers and methods thereof for wound healing
US9387250B2 (en) 2013-03-15 2016-07-12 Rutgers, The State University Of New Jersey Therapeutic compositions for bone repair
CN103203039B (zh) * 2013-04-12 2015-02-11 西南交通大学 一种医用金属表面具有骨诱导与抗菌性作用涂层的制备方法
WO2014194055A1 (en) 2013-05-29 2014-12-04 Rutgers, The State University Of New Jersey Antioxidant-based poly(anhydride-esters)
US10023521B2 (en) 2014-06-13 2018-07-17 Rutgers, The State University Of New Jersey Process and intermediates for preparing poly(anhydride-esters)
WO2016164898A1 (en) 2015-04-10 2016-10-13 Rutgers, The State University Of New Jersey Kojic acid polymers
WO2017019832A1 (en) * 2015-07-29 2017-02-02 Medivation Technologies, Inc. Methods and compositions using repair cells and cationic dyes
CN109054000B (zh) * 2018-07-24 2021-08-06 中山大学 一种基于聚水杨酸的纳米载药体系及其制备方法和应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001041753A2 (en) * 1999-12-07 2001-06-14 Rutgers, The State University Of New Jersey Therapeutic compositions and methods for treating periodontitis with antiinflamatory compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6486214B1 (en) * 1997-09-10 2002-11-26 Rutgers, The State University Of New Jersey Polyanhydride linkers for production of drug polymers and drug polymer compositions produced thereby

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001041753A2 (en) * 1999-12-07 2001-06-14 Rutgers, The State University Of New Jersey Therapeutic compositions and methods for treating periodontitis with antiinflamatory compounds

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DOMB ABRAHAM J. ET AL.: "Poly(anhydrides). 2. One-step polymerization using phosgene or diphosgene as coupling agents", MACROMOLECULES, vol. 21, no. 7, July 1988 (1988-07-01), pages 1925 - 1929, XP002619092 *
DOMB ET AL: "Biodegradable polymers derived from amino acids", BIOMATERIALS, ELSEVIER SCIENCE PUBLISHERS BV., BARKING, GB, vol. 11, no. 9, 1 November 1990 (1990-11-01), pages 686 - 689, XP024141859, ISSN: 0142-9612, [retrieved on 19901101], DOI: 10.1016/0142-9612(90)90027-N *
ERDMANN L ET AL: "Degradable poly(anhydride ester) implants: effects of localized salicylic acid release on bone", BIOMATERIALS, ELSEVIER SCIENCE PUBLISHERS BV., BARKING, GB, vol. 21, no. 24, 15 December 2000 (2000-12-15), pages 2507 - 2512, XP004217414, ISSN: 0142-9612, DOI: 10.1016/S0142-9612(00)00118-6 *
ERDMANN L ET AL: "Synthesis and degradation characteristics of salicylic acid-derived poly(anhydride-esters)", BIOMATERIALS, ELSEVIER SCIENCE PUBLISHERS BV., BARKING, GB, vol. 21, no. 19, 1 October 2000 (2000-10-01), pages 1941 - 1946, XP004209720, ISSN: 0142-9612, DOI: 10.1016/S0142-9612(00)00073-9 *
KUMAR NEERAJ ET AL: "Polyanhydrides: An overview.", ADVANCED DRUG DELIVERY REVIEWS, vol. 54, no. 7, 16 October 2002 (2002-10-16), pages 889 - 910, XP002619091, ISSN: 0169-409X *

Also Published As

Publication number Publication date
WO2005042600A2 (en) 2005-05-12
CA2527495A1 (en) 2005-05-12
WO2005042600A3 (en) 2005-11-10
EP1631300A2 (de) 2006-03-08

Similar Documents

Publication Publication Date Title
EP1631300A4 (de) Hochmolekulare polymere, vorrichtungen und verfahren zur herstellung und verwendung
MX261407B (es) Metodos y composiciones de polimeros asociativos dilatables en alcali.
EP1620450A4 (de) Polymere oligonukleotid-prodrugs
DE50203791D1 (de) Aloxysilanterminierte polymere enthaltende vernetzbare polymerabmischungen
GB2453457A (en) Indenofluorene polymer based organic semiconductor materials
NO20040398L (no) Hydrofobe assosiative polymerer, blandinger med slike og anvendelse av slike.
EP1637548A4 (de) Butadienpolymer und herstellungsverfahren dafür sowie daraus hergestellte oder diese enthaltende kautschukzusammensetzungen und reifen
EP1492856A4 (de) Polymere antioxidantien
DE602004005333D1 (de) Planarer polymer-speicherbaustein
EP1350763A4 (de) Sapo-11 molekularsieb : sein syntheseverfahren und katalysator das molekularsieb enthaltend
EP1528074A4 (de) Neues triarylaminpolymer, verfahren zu seiner herstellung und verwendung davon
DE602004013003D1 (de) Halbleitendes Polymer
WO2005096744A3 (en) Oriented polymer fibers and methods for fabricating thereof
BR0310023B1 (pt) dispersço de polÍmero solével em Água, mÉtodo de produÇço de uma dispersço de polÍmero solével em Água e utilizaÇço de uma dispersço de polÍmero solével em Água.
AU2003229264A1 (en) Oligomers and polymers containing sulfinate groups, and methods for producing the same
AU2003218385A8 (en) High molecular weight polymers
EP1569607A4 (de) Zähe polymere
DE60323993D1 (de) Embran aus poly(m-phenylenisophthal-amid)
DE60231799D1 (de) Polymer mit 9-oxo-9-phosphafluoren-2,7-diyl-gerüstlung
DE602004030645D1 (de) Resistpolymer, Resistzusammensetzung und Mustererzeugungsverfahren
PL374040A1 (en) Monomer compound comprising several cationic groups, process for making the same, and polymers comprising units deriving therefrom
PL1877622T3 (pl) Polimery strukturyzowane o dużym ciężarze cząsteczkowym, sposoby ich wytwarzania i stosowania
ITTS20030008A1 (it) Sistema di connessione sui montanti di ante,
EP1951413A4 (de) Matrix und dynamisches polymersystem und zusammensetzungen für die mikrokanaltrennung
MXPA02012259A (es) Polimeros que estan modificados por medio de grupos funcionales.

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20051205

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL HR LT LV MK

DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20110207

RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 47/48 20060101ALI20110201BHEP

Ipc: A61K 31/74 20060101AFI20051117BHEP

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20120103