EP1559676A3 - Dispositif micro-structure et procédé pour le remplissage exempt de bulles d'un dispositif servant à guider des liquides - Google Patents

Dispositif micro-structure et procédé pour le remplissage exempt de bulles d'un dispositif servant à guider des liquides Download PDF

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Publication number
EP1559676A3
EP1559676A3 EP04029633A EP04029633A EP1559676A3 EP 1559676 A3 EP1559676 A3 EP 1559676A3 EP 04029633 A EP04029633 A EP 04029633A EP 04029633 A EP04029633 A EP 04029633A EP 1559676 A3 EP1559676 A3 EP 1559676A3
Authority
EP
European Patent Office
Prior art keywords
liquid
bubble
microstructured
free filling
liquids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP04029633A
Other languages
German (de)
English (en)
Other versions
EP1559676B1 (fr
EP1559676A2 (fr
Inventor
Gert Dr. Blankenstein
Claus Dipl.-Ing. Marquordt
Ralf-Peter Dr. Dipl.-Ing. Peters
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Microparts GmbH
Original Assignee
Boehringer Ingelheim Microparts GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Microparts GmbH filed Critical Boehringer Ingelheim Microparts GmbH
Publication of EP1559676A2 publication Critical patent/EP1559676A2/fr
Publication of EP1559676A3 publication Critical patent/EP1559676A3/fr
Application granted granted Critical
Publication of EP1559676B1 publication Critical patent/EP1559676B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502723—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by venting arrangements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0621—Control of the sequence of chambers filled or emptied
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0684—Venting, avoiding backpressure, avoid gas bubbles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0688—Valves, specific forms thereof surface tension valves, capillary stop, capillary break
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y10T436/110833—Utilizing a moving indicator strip or tape
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y10T436/111666—Utilizing a centrifuge or compartmented rotor
EP04029633.7A 2003-12-20 2004-12-15 Dispositif micro-structure et procédé pour le remplissage exempt de bulles d'un dispositif servant à guider des liquides Active EP1559676B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10360220 2003-12-20
DE10360220A DE10360220A1 (de) 2003-12-20 2003-12-20 Mikrostrukturierte Anordnung zur blasenfreien Befüllung zumindest eines Systems zur Ableitung von Flüssigkeiten, Vorrichtung mit einer solchen Anordnung und Befüllungsverfahren

Publications (3)

Publication Number Publication Date
EP1559676A2 EP1559676A2 (fr) 2005-08-03
EP1559676A3 true EP1559676A3 (fr) 2008-12-03
EP1559676B1 EP1559676B1 (fr) 2016-06-29

Family

ID=34638731

Family Applications (1)

Application Number Title Priority Date Filing Date
EP04029633.7A Active EP1559676B1 (fr) 2003-12-20 2004-12-15 Dispositif micro-structure et procédé pour le remplissage exempt de bulles d'un dispositif servant à guider des liquides

Country Status (5)

Country Link
US (1) US7485118B2 (fr)
EP (1) EP1559676B1 (fr)
JP (1) JP4931345B2 (fr)
CN (2) CN1695808A (fr)
DE (1) DE10360220A1 (fr)

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US20070280856A1 (en) * 2006-06-02 2007-12-06 Applera Corporation Devices and Methods for Controlling Bubble Formation in Microfluidic Devices
US20070280857A1 (en) * 2006-06-02 2007-12-06 Applera Corporation Devices and Methods for Positioning Dried Reagent In Microfluidic Devices
EP1977829A1 (fr) * 2007-03-29 2008-10-08 Roche Diagnostics GmbH Dispositif pour effectuer plusieurs analyses en parallèle
CN104062454B (zh) 2007-10-30 2016-01-20 松下健康医疗控股株式会社 分析用仪器
US8263025B2 (en) * 2008-02-01 2012-09-11 Nippon Telegraph And Telephone Corporation Flow cell
JP5475692B2 (ja) 2008-02-27 2014-04-16 ベーリンガー インゲルハイム マイクロパーツ ゲゼルシャフト ミット ベシュレンクテル ハフツング 血漿の分離装置
KR100998535B1 (ko) * 2008-04-11 2010-12-07 인싸이토 주식회사 나노틈새를 가지는 미세유체 채널이 구비된 미세유체회로소자 및 이의 제조 방법
US10005082B2 (en) 2008-04-11 2018-06-26 Incyto Co., Ltd. Microfluidic circuit element comprising microfluidic channel with nano interstices and fabrication method thereof
KR101390717B1 (ko) 2008-09-02 2014-04-30 삼성전자주식회사 미세유동장치 및 미세유동장치에의 시료주입방법
EP2213364A1 (fr) * 2009-01-30 2010-08-04 Albert-Ludwigs-Universität Freiburg Motifs de guide de phase pour la manipulation de liquides
WO2010119377A1 (fr) * 2009-04-15 2010-10-21 Koninklijke Philips Electronics N.V. Chambre à fluide sans gaz
EP2486978A1 (fr) 2010-10-28 2012-08-15 Roche Diagnostics GmbH Support de test microfluidique destiné à répartir une quantité de liquide en quantités partielles
EP2455162A1 (fr) * 2010-10-29 2012-05-23 Roche Diagnostics GmbH Elément micro-fluidique destiné à l'analyse d'un échantillon de liquide
WO2013004673A1 (fr) 2011-07-05 2013-01-10 Boehringer Ingelheim Microparts Gmbh Structure microfluidique comportant des creux
USD978375S1 (en) 2013-03-13 2023-02-14 Abbott Laboratories Reagent container
US10058866B2 (en) 2013-03-13 2018-08-28 Abbott Laboratories Methods and apparatus to mitigate bubble formation in a liquid
US9535082B2 (en) 2013-03-13 2017-01-03 Abbott Laboratories Methods and apparatus to agitate a liquid
USD962471S1 (en) 2013-03-13 2022-08-30 Abbott Laboratories Reagent container
WO2017117553A1 (fr) * 2015-12-31 2017-07-06 Mec Dynamics Procédés et systèmes micro-mécaniques pour réaliser des analyses
US10258741B2 (en) 2016-12-28 2019-04-16 Cequr Sa Microfluidic flow restrictor and system
CN109072893B (zh) * 2017-01-09 2019-11-29 华为技术有限公司 一种电液动力装置以及包含电液动力装置的系统
CN108722504A (zh) * 2017-04-19 2018-11-02 光宝电子(广州)有限公司 检测装置及其注入口结构
KR102012243B1 (ko) * 2017-09-19 2019-11-04 한국기계연구원 미세 서브 유로를 갖는 마이크로 유체 소자 및 이를 제조하기 위한 몰드

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EP1013341A2 (fr) * 1998-12-23 2000-06-28 MICROPARTS GESELLSCHAFT FÜR MIKROSTRUKTURTECHNIK mbH Dispositif de drainage d'un liquide hors d'un capillaire
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WO2001026813A2 (fr) * 1999-10-08 2001-04-19 Micronics, Inc. Logique a microfluides sans pompe
EP1201304A2 (fr) * 2000-10-25 2002-05-02 MICROPARTS GESELLSCHAFT FÜR MIKROSTRUKTURTECHNIK mbH Plateforme microstructurée pour l'examen d'un liquide
US20020081669A1 (en) * 2000-07-28 2002-06-27 Gabriel Festoc Device for thermo-dependent chain reaction amplification of target nucleic acid sequences, measured in real-time
WO2003025547A1 (fr) * 2001-09-21 2003-03-27 Biomedlab Corporation Procede et dispositif permettant de balayer des analytes au moyen de resonance plasmonique de surface

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EP1013341A2 (fr) * 1998-12-23 2000-06-28 MICROPARTS GESELLSCHAFT FÜR MIKROSTRUKTURTECHNIK mbH Dispositif de drainage d'un liquide hors d'un capillaire
US6193471B1 (en) * 1999-06-30 2001-02-27 Perseptive Biosystems, Inc. Pneumatic control of formation and transport of small volume liquid samples
WO2001026813A2 (fr) * 1999-10-08 2001-04-19 Micronics, Inc. Logique a microfluides sans pompe
US20020081669A1 (en) * 2000-07-28 2002-06-27 Gabriel Festoc Device for thermo-dependent chain reaction amplification of target nucleic acid sequences, measured in real-time
EP1201304A2 (fr) * 2000-10-25 2002-05-02 MICROPARTS GESELLSCHAFT FÜR MIKROSTRUKTURTECHNIK mbH Plateforme microstructurée pour l'examen d'un liquide
WO2003025547A1 (fr) * 2001-09-21 2003-03-27 Biomedlab Corporation Procede et dispositif permettant de balayer des analytes au moyen de resonance plasmonique de surface

Also Published As

Publication number Publication date
EP1559676B1 (fr) 2016-06-29
EP1559676A2 (fr) 2005-08-03
JP4931345B2 (ja) 2012-05-16
CN101632947B (zh) 2012-08-08
US7485118B2 (en) 2009-02-03
CN101632947A (zh) 2010-01-27
DE10360220A1 (de) 2005-07-21
US20050169778A1 (en) 2005-08-04
CN1695808A (zh) 2005-11-16
JP2005177754A (ja) 2005-07-07

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