EP1550512B1 - Fluid applying device for a fluid dispensing apparatus - Google Patents
Fluid applying device for a fluid dispensing apparatus Download PDFInfo
- Publication number
- EP1550512B1 EP1550512B1 EP04405718A EP04405718A EP1550512B1 EP 1550512 B1 EP1550512 B1 EP 1550512B1 EP 04405718 A EP04405718 A EP 04405718A EP 04405718 A EP04405718 A EP 04405718A EP 1550512 B1 EP1550512 B1 EP 1550512B1
- Authority
- EP
- European Patent Office
- Prior art keywords
- applicator
- enclosure
- dispensing
- glued
- tissue
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000012530 fluid Substances 0.000 title 2
- 239000000758 substrate Substances 0.000 claims abstract 4
- 238000004026 adhesive bonding Methods 0.000 claims description 4
- 238000000034 method Methods 0.000 claims 1
- 239000000853 adhesive Substances 0.000 description 7
- 230000001070 adhesive effect Effects 0.000 description 7
- 210000001519 tissue Anatomy 0.000 description 7
- 210000004072 lung Anatomy 0.000 description 5
- 238000005516 engineering process Methods 0.000 description 4
- 239000004744 fabric Substances 0.000 description 3
- 210000004185 liver Anatomy 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 239000004570 mortar (masonry) Substances 0.000 description 3
- 239000011248 coating agent Substances 0.000 description 2
- 238000000576 coating method Methods 0.000 description 2
- 238000009499 grossing Methods 0.000 description 2
- 239000004568 cement Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229910052602 gypsum Inorganic materials 0.000 description 1
- 239000010440 gypsum Substances 0.000 description 1
- 230000000284 resting effect Effects 0.000 description 1
- 239000000565 sealant Substances 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05C—APPARATUS FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05C17/00—Hand tools or apparatus using hand held tools, for applying liquids or other fluent materials to, for spreading applied liquids or other fluent materials on, or for partially removing applied liquids or other fluent materials from, surfaces
- B05C17/005—Hand tools or apparatus using hand held tools, for applying liquids or other fluent materials to, for spreading applied liquids or other fluent materials on, or for partially removing applied liquids or other fluent materials from, surfaces for discharging material from a reservoir or container located in or on the hand tool through an outlet orifice by pressure without using surface contacting members like pads or brushes
- B05C17/00503—Details of the outlet element
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/00491—Surgical glue applicators
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05C—APPARATUS FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05C17/00—Hand tools or apparatus using hand held tools, for applying liquids or other fluent materials to, for spreading applied liquids or other fluent materials on, or for partially removing applied liquids or other fluent materials from, surfaces
- B05C17/005—Hand tools or apparatus using hand held tools, for applying liquids or other fluent materials to, for spreading applied liquids or other fluent materials on, or for partially removing applied liquids or other fluent materials from, surfaces for discharging material from a reservoir or container located in or on the hand tool through an outlet orifice by pressure without using surface contacting members like pads or brushes
- B05C17/00553—Hand tools or apparatus using hand held tools, for applying liquids or other fluent materials to, for spreading applied liquids or other fluent materials on, or for partially removing applied liquids or other fluent materials from, surfaces for discharging material from a reservoir or container located in or on the hand tool through an outlet orifice by pressure without using surface contacting members like pads or brushes with means allowing the stock of material to consist of at least two different components
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05C—APPARATUS FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05C5/00—Apparatus in which liquid or other fluent material is projected, poured or allowed to flow on to the surface of the work
- B05C5/02—Apparatus in which liquid or other fluent material is projected, poured or allowed to flow on to the surface of the work the liquid or other fluent material being discharged through an outlet orifice by pressure, e.g. from an outlet device in contact or almost in contact, with the work
- B05C5/0254—Coating heads with slot-shaped outlet
Definitions
- the present invention relates to an applicator device for a dispensing device according to the preamble of claim 1, in particular for a cartridge and is intended for the medical technology for bonding tissue such as lung or liver.
- an applicator device according to the preamble of claim 1 is known, which is intended for the application of mortar and the like and having a straight, the wall facing portion having a nearly the entire bottom engaging mortar opening.
- Such a device is not suitable for the bonding of tissue parts, since the large opening does not allow accurate dosing and gluing and smoothing.
- U.S.-A-2,804,767 discloses a device which is intended for the application of gypsum, cement or mortar and has an angled application part, wherein the top of the applicator portion substantially surmounting its underside, thus a relatively large amount of the material can flow out. However, this is not suitable for the intended use.
- EP-A-1 157 748 is a glueing device known with a Auslassteil whose underside has a kink.
- an object of the present invention to provide an improved applicator device for a dispensing device, with which an efficient and gentle application of adhesive or sealant in medical technology, on tissue such as lung, liver or the like is possible.
- An applicator device which achieves this object is defined in claim 1.
- the application device 1 consists of a two-part housing 2 with connection part 3, wherein the housing 2 consists of the lower part 4 and the lid-shaped upper part 5.
- Out Fig. 1 shows that the housing 2 conically widened outward, that is to the discharge slot 6 out.
- the slot width may be 12 or 16 mm and the slot thickness 0.1 - 0.3 mm.
- the lower and upper sides of the housing are defined with respect to the parts to be bonded, with housing part 4 resting on the tissue, for example lung tissue, and therefore the lower part and part 5 are accordingly the upper part.
- the upper part 5 may also be slightly longer than the lower part 4, wherein the difference 6A in the present embodiment is 0.5 mm. This can be achieved in certain cases that the emerging from the discharge slot 6 adhesive turns towards the tissue.
- FIG. 2 also shows that at least the housing bottom side 4A is curved, this curvature as drawn continuous, circular arc-shaped and with a radius can be defined to have a different curvature such as elliptical or parabolic. It is important that the longitudinal axis of the connection part 3 with the surface to be bonded, or the housing bottom side 4A, forms an angle which may be different depending on the application.
- the smoothing function also depends on the surface finish and the material used on the underside of the housing.
- Fig. 3 the lower part 4 of the housing is visible from the inside, with three guide webs 7 being shown here. These guide webs have the task of distributing the adhesive coming from the connector to achieve a uniform outflow.
- connection part 3 is designed to be plugged into the outlet of a mixer, but of course connection parts with other dimensions and configurations are possible in order to be able to connect to a specific mixer or dispensing device.
- the housing 2 is as mentioned above, in two parts and is also made in two parts, wherein the lower part 4 according to Fig. 3 the upper part 5, which is designed as a lid, attached and connected to the lower part.
- the compound can be prepared in a variety of ways, for example by gluing or ultrasonic welding.
- the curvature of the base 4 smoothes the fabric, whereupon the adhesive is dispensed. Due to the conically widening shape of the housing and a steadily decreasing overall cross section on the one hand and by the provision of guide webs on the other hand results in a steady uniform flow of the adhesive on the smoothed surface, the height of the discharge slot Sowoehl depends on the viscosity and the required discharge volume. In certain applications, the length of protruding part 6A may play a role.
- the housing 2 is continuously curved.
- the angle ⁇ between the longitudinal axis of the connecting part 3 and the outlet end 11 of the bottom can be between 5 ° and 90 °, preferably between 10 ° and 90 °.
- FIGS. 5A to 5C It is shown that the discharge end 11 having the discharge slot is straight as shown in FIG FIG. 1 , the outlet end 12 concave as in FIG. 5B or the outlet end 13 convex as in FIG. 5C can be.
- FIGS. 6A to 6G show various possible cross sections of the discharge slot, wherein FIG. 6F corresponds to the cross section of the discharge slot 6.
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Mechanical Engineering (AREA)
- Coating Apparatus (AREA)
- Surgical Instruments (AREA)
- Medicinal Preparation (AREA)
- Closures For Containers (AREA)
- Nozzles (AREA)
- Seal Device For Vehicle (AREA)
Abstract
Description
Die vorliegende Erfindung bezieht sich auf eine Auftragvorrichtung für ein Austraggerät gemäss dem Oberbegriff von Anspruch 1, insbesondere für eine Kartusche und ist für die Medizinaltechnik zum Verkleben von Gewebe wie beispielsweise Lunge oder Leber gedacht.The present invention relates to an applicator device for a dispensing device according to the preamble of claim 1, in particular for a cartridge and is intended for the medical technology for bonding tissue such as lung or liver.
Das Verkleben von Geweben wie Lunge, Leber oder Milz erlangt in der Medizin einen stetig wachsenden Stellenwert, doch sind bis jetzt keine dafür speziell ausgebildeten Vorrichtungen bekannt, während herkömmliche Vorsätze an Mischern keine befriedigende Lösung darstellen.The bonding of tissues such as the lungs, liver or spleen is becoming increasingly important in medicine, but so far no specially trained devices are known, while conventional intentions of mixers are not a satisfactory solution.
Das gilt auch im grösseren Massstab für das Verkleben, Beschichten oder Versiegeln von Stoffen, Zeltplanen, geschäumten Teilen oder dergleichen Materialien mit unebener Oberfläche.This also applies on a larger scale for the bonding, coating or sealing of fabrics, tarpaulins, foamed parts or similar materials with uneven surface.
Aus der
Aus der
Diese vorbekannten Geräte sind zum Verkleben oder definierten Beschichten von unebenen, empfindlichen und nachgebenden Oberflächen in der Medizinaltechnik, wie Lunge oder dergleichen, nicht geeignet, da das Hauptproblem dort darin besteht, dass eine solche Unterlage sehr uneben und weich ist, wodurch ein effizientes und gleichmässiges Auftragen von Klebstoff sehr problematisch ist.These prior art devices are not suitable for bonding or defined coating of uneven, delicate and yielding surfaces in medical technology, such as lungs or the like, since the main problem is that such a support is very uneven and soft, thereby providing an efficient and uniform Applying adhesive is very problematic.
Davon ausgehend ist es Aufgabe der vorliegenden Erfindung eine verbesserte Auftragvorrichtung für ein Austraggerät anzugeben, mit der ein effizientes und schonendes Auftragen von Kleb- oder Dichtstoff in der Medizinaltechnik, auf Gewebe wie Lunge, Leber oder dergleichen möglich ist. Eine Auftragvorrichtung, die diese Aufgabe löst, ist in Patentanspruch 1 definiert.On this basis, it is an object of the present invention to provide an improved applicator device for a dispensing device, with which an efficient and gentle application of adhesive or sealant in medical technology, on tissue such as lung, liver or the like is possible. An applicator device which achieves this object is defined in claim 1.
Die Erfindung wird im Folgenden anhand von Zeichnungen von Ausführungsbeispielen näher erläutert.
- Fig. 1
- zeigt eine erfindungsgemässe Auftragvorrichtung von oben,
- Fig. 2
- zeigt einen Schnitt gemäss Linie II-II in
Fig. 1 , - Fig. 2A
- zeigt in einer Ausschnittsvergrösserung eine Ausführungsvariante des Auslassendes,
- Fig. 3
- zeigt einen Schnitt gemäss Linie II-II in
Fig. 2 , Figuren 4- zeigt eine Ausführungsform des Gehäuses der Auftragvorrichtung, die
- Figuren 5A bis 5C
- zeigen drei Ausführungsvarianten bezüglich der Form des Auslassendes, ünd die
Figuren 6A - 6G- zeigen Ausführungsvarianten bezüglich des Austrittsquerschnitts.
- Fig. 1
- shows an inventive applicator device from above,
- Fig. 2
- shows a section along the line II-II in
Fig. 1 . - Fig. 2A
- shows in a detail enlargement a variant of the outlet end,
- Fig. 3
- shows a section along the line II-II in
Fig. 2 . - FIGS. 4
- shows an embodiment of the housing of the applicator, the
- FIGS. 5A to 5C
- show three embodiments with respect to the shape of the outlet end, and the
- Figures 6A-6G
- show embodiments with respect to the outlet cross-section.
Die Auftragvorrichtung 1 besteht aus einem zweiteiligen Gehäuse 2 mit Anschlussteil 3, wobei das Gehäuse 2 aus dem Unterteil 4 und dem deckelförmigen Oberteil 5 besteht. Aus
Im Ausführungsbeispiel gemäss den
Wie aus
Aus
In
Das Anschlussteil 3 ist ausgebildet, in den Auslass eines Mischers gesteckt zu werden, doch sind selbstverständlich Anschlussteile mit anderen Dimensionen und Ausgestaltungen möglich, um eine Verbindung zu einem bestimmten Mischer oder Austraggerät herstellen zu können.The
Das Gehäuse 2 ist wie eingangs erwähnt, zweiteilig und wird auch zweiteilig hergestellt, wobei auf das untere Teil 4 gemäss
Beim Auftragen eines Klebstoffes auf ein Gewebe mit unebener Oberfläche wird durch die Krümmung des Unterteils 4 das Gewebe geglättet, woraufhin der Klebstoff abgegeben wird. Durch die konisch sich verbreiternde Form des Gehäuses und eines sich stetig verkleinernden Gesamtquerschnittes einerseits und durch das Anbringen von Leitstegen andererseits ergibt sich ein stetiger gleichmässiger Fluss des Klebstoffes auf die geglättete Unterlage, wobei die Höhe des Austragschlitzes Sowoehl von der Viskosität als auch vom erforderlichen Austragvolumen abhängig ist. Bei bestimmten Anwendungen kann die Länge des vorstehenden Teils 6A eine Rolle spielen.When an adhesive is applied to a fabric having an uneven surface, the curvature of the
Ausgehend vom oben dargestellten Ausführungsbeispiel gemäss den
Gemäss
In den
Die
Je nach Anwendungszweck ist eine Variationsbreite des Austragschlitzquerschnittes, der Dimensionen der Leitstege etc. im unteren Millimeterbereich möglich.Depending on the application, a variation of the Austragschlitzquerschnittes, the dimensions of the guide webs, etc. in the lower millimeter range is possible.
Claims (7)
- Applicator (1) for a dispensing appliance for gluing a substrate, including an adapter (3) for connection to a mixer or to the dispensing appliance itself as well as a dispensing slot (6), the underside (4A) of the enclosure (2) of the applicator (1) that is turned towards the substrate to be glued forming an angle (α) with the longitudinal axis of the adapter (3), characterised in that:- the applicator (1) is intended for medicinal technique,- the substrate that is to be glued is a tissue,- the enclosure (2) of the applicator (1) is composed of a lower portion (4) and an upper portion (5),- the side (4A) of the enclosure (2) that is turned towards the glued tissue is curved, the curvature being essentially continuous,- the dispensing slot (6) is oblong and forms the end of the enclosure (2) opposite the adapter (3),- the enclosure (2) is conically enlarged towards the oblong dispensing slot (6).
- Applicator (1) according to claim 1, characterised in that the angle (α) is comprised between 5° and 90°.
- Applicator (1) according to claim 1 or 2, characterised in that the lower portion (4) of the enclosure (2) of the device, which is turned towards the glued tissue, is provided with guiding walls (7) on its inner surface.
- Applicator (1) according to any one of claims 1 to 3, characterised in that the upper portion (5) of the enclosure (2) of the device, which is turned away from the glued tissue, is longer than the lower portion (4) of the enclosure (2) of the device that is turned towards the glued tissue.
- Applicator (1) according to any one of claims 1 to 4, characterised in that the curvature is circle arc shaped.
- Applicator (1) according to any one of claims 1 to 5, characterised in that the dispensing end provided with the dispensing slot (6) is straight (11), concave (12), or convex (13) in shape.
- Applicator (1) according to any one of claims 1 to 6, characterised in that the cross-section of the dispensing slot (6) is rectangular, angled, partly or entirely arc-shaped, or oval.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH21222003 | 2003-12-12 | ||
CH21222003 | 2003-12-12 |
Publications (3)
Publication Number | Publication Date |
---|---|
EP1550512A2 EP1550512A2 (en) | 2005-07-06 |
EP1550512A3 EP1550512A3 (en) | 2008-02-27 |
EP1550512B1 true EP1550512B1 (en) | 2009-09-16 |
Family
ID=34558441
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP04405718A Active EP1550512B1 (en) | 2003-12-12 | 2004-11-22 | Fluid applying device for a fluid dispensing apparatus |
Country Status (9)
Country | Link |
---|---|
US (1) | US7325995B2 (en) |
EP (1) | EP1550512B1 (en) |
JP (1) | JP2005169125A (en) |
CN (1) | CN1626045B (en) |
AT (1) | ATE442914T1 (en) |
DE (1) | DE502004010065D1 (en) |
DK (1) | DK1550512T3 (en) |
ES (1) | ES2331474T3 (en) |
PT (1) | PT1550512E (en) |
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US7914511B2 (en) | 2006-10-18 | 2011-03-29 | Ethicon Endo-Surgery, Inc. | Use of biosurgical adhesive as bulking agent |
US7749235B2 (en) | 2006-10-20 | 2010-07-06 | Ethicon Endo-Surgery, Inc. | Stomach invagination method and apparatus |
US7658305B2 (en) | 2006-10-25 | 2010-02-09 | Ethicon Endo-Surgery, Inc. | Adhesive applier with articulating tip |
US8876844B2 (en) | 2006-11-01 | 2014-11-04 | Ethicon Endo-Surgery, Inc. | Anastomosis reinforcement using biosurgical adhesive and device |
US7892250B2 (en) | 2006-11-01 | 2011-02-22 | Ethicon Endo-Surgery, Inc. | Use of biosurgical adhesive on inflatable device for gastric restriction |
US7833216B2 (en) | 2006-11-08 | 2010-11-16 | Ethicon Endo-Surgery, Inc. | Fluid plunger adhesive dispenser |
CN101557996A (en) | 2006-12-15 | 2009-10-14 | 3M创新有限公司 | Mixing and dispensing curable multi-component materials |
DE202008007801U1 (en) | 2007-09-19 | 2008-08-21 | Kettenbach Gmbh & Co. Kg | container |
DE102008047234B4 (en) * | 2008-09-12 | 2018-12-06 | Henkel Ag & Co. Kgaa | Repair nozzle and repair system |
US20100237104A1 (en) * | 2009-03-17 | 2010-09-23 | Schneider Mark C | Cove Base Nozzle for Dispensing Applications |
US8985402B2 (en) * | 2009-03-17 | 2015-03-24 | Mark C. Schneider | Cove base nozzle for dispensing applications |
DE102009034774A1 (en) * | 2009-07-25 | 2011-01-27 | Bona Gmbh Deutschland | Application nozzle for viscous adhesives |
FR2948584B1 (en) * | 2009-07-30 | 2012-08-03 | Prod Dentaires Pierre Rolland | APPLICATION TIP |
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US8608642B2 (en) | 2010-02-25 | 2013-12-17 | Ethicon Endo-Surgery, Inc. | Methods and devices for treating morbid obesity using hydrogel |
US20130279967A1 (en) * | 2012-04-20 | 2013-10-24 | Andreas Otto | Nozzle |
US10413930B2 (en) | 2013-07-18 | 2019-09-17 | Lisa Marie Evans | System and method for application of a surface compound |
USD739727S1 (en) * | 2014-02-10 | 2015-09-29 | 3M Innovative Properties Company | Combined container and tool |
US10390828B2 (en) * | 2014-06-10 | 2019-08-27 | Ethicon Llc | Devices and methods for sealing staples in tissue |
US10780454B2 (en) * | 2016-02-05 | 2020-09-22 | Sashco, Inc. | Sealant applicator and methods of use |
EP3211216A1 (en) * | 2016-02-24 | 2017-08-30 | Wind Composite Services Group, LLC | Nozzle assembly for repairing or upgrading wind turbine blades, method thereof and kit for the same |
US10231846B2 (en) | 2016-08-19 | 2019-03-19 | Stryker European Holdings I, Llc | Bone graft delivery loading assembly |
US10343183B2 (en) * | 2016-12-21 | 2019-07-09 | Stoneridge Kitchen & Bath Llc | Glue gun |
JP6598829B2 (en) * | 2017-08-28 | 2019-10-30 | 朝明精工株式会社 | Paint nozzle head |
US12059701B2 (en) * | 2018-02-21 | 2024-08-13 | Scott Folley | Caulk tube repair system and apparatus |
FR3079430A1 (en) * | 2018-03-29 | 2019-10-04 | Primequal Sa | APPARATUS AND TIP FOR APPLYING AND SPREADING A PRODUCT LIQUID, GEL OR PULP |
EP3560427A1 (en) * | 2018-04-24 | 2019-10-30 | Gecko Biomedical | Applicator for depositing a layer of adhesive or sealant composition on a biological and/or prosthetic tissue |
CN108815687B (en) * | 2018-04-27 | 2020-07-28 | 河南中医药大学 | Esophagus cancer chemotherapy device |
BR112021010260A2 (en) | 2018-11-29 | 2021-08-17 | Ethicon, Inc. | operating room coating method and applicator |
US11712229B2 (en) * | 2020-05-28 | 2023-08-01 | Ethicon, Inc. | Systems, devices and methods for dispensing and curing silicone based topical skin adhesives |
US11589867B2 (en) | 2020-05-28 | 2023-02-28 | Ethicon, Inc. | Anisotropic wound closure systems |
US11479669B2 (en) | 2020-05-28 | 2022-10-25 | Ethicon, Inc. | Topical skin closure compositions and systems |
US11718753B2 (en) | 2020-05-28 | 2023-08-08 | Ethicon, Inc. | Topical skin closure compositions and systems |
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-
2004
- 2004-11-22 DK DK04405718T patent/DK1550512T3/en active
- 2004-11-22 DE DE502004010065T patent/DE502004010065D1/en active Active
- 2004-11-22 AT AT04405718T patent/ATE442914T1/en not_active IP Right Cessation
- 2004-11-22 ES ES04405718T patent/ES2331474T3/en active Active
- 2004-11-22 PT PT04405718T patent/PT1550512E/en unknown
- 2004-11-22 EP EP04405718A patent/EP1550512B1/en active Active
- 2004-12-02 US US11/001,645 patent/US7325995B2/en active Active
- 2004-12-07 CN CN2004100971011A patent/CN1626045B/en active Active
- 2004-12-10 JP JP2004358509A patent/JP2005169125A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
ATE442914T1 (en) | 2009-10-15 |
US7325995B2 (en) | 2008-02-05 |
EP1550512A2 (en) | 2005-07-06 |
EP1550512A3 (en) | 2008-02-27 |
CN1626045A (en) | 2005-06-15 |
DE502004010065D1 (en) | 2009-10-29 |
CN1626045B (en) | 2010-04-14 |
ES2331474T3 (en) | 2010-01-05 |
PT1550512E (en) | 2009-11-30 |
US20050127119A1 (en) | 2005-06-16 |
DK1550512T3 (en) | 2009-12-07 |
JP2005169125A (en) | 2005-06-30 |
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