EP1546372A4 - Zellassay mit induzierbarer fokaler adhäsionskinase - Google Patents

Zellassay mit induzierbarer fokaler adhäsionskinase

Info

Publication number
EP1546372A4
EP1546372A4 EP03797456A EP03797456A EP1546372A4 EP 1546372 A4 EP1546372 A4 EP 1546372A4 EP 03797456 A EP03797456 A EP 03797456A EP 03797456 A EP03797456 A EP 03797456A EP 1546372 A4 EP1546372 A4 EP 1546372A4
Authority
EP
European Patent Office
Prior art keywords
cell assay
focal adhesion
adhesion kinase
kinase cell
inducible
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03797456A
Other languages
English (en)
French (fr)
Other versions
EP1546372A2 (de
Inventor
Walter Gregory Roberts
Pamela Matthews Whalen
Ethan James Tekly Ung
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Products Inc
Original Assignee
Pfizer Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc filed Critical Pfizer Products Inc
Publication of EP1546372A2 publication Critical patent/EP1546372A2/de
Publication of EP1546372A4 publication Critical patent/EP1546372A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/91—Transferases (2.)
    • G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • G01N2333/91205—Phosphotransferases in general

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP03797456A 2002-09-19 2003-09-08 Zellassay mit induzierbarer fokaler adhäsionskinase Withdrawn EP1546372A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41207802P 2002-09-19 2002-09-19
US412078P 2002-09-19
PCT/IB2003/003968 WO2004027018A2 (en) 2002-09-19 2003-09-08 Inducible focal adhesion kinase cell assay

Publications (2)

Publication Number Publication Date
EP1546372A2 EP1546372A2 (de) 2005-06-29
EP1546372A4 true EP1546372A4 (de) 2006-08-23

Family

ID=32030798

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03797456A Withdrawn EP1546372A4 (de) 2002-09-19 2003-09-08 Zellassay mit induzierbarer fokaler adhäsionskinase

Country Status (9)

Country Link
EP (1) EP1546372A4 (de)
JP (1) JP2006500022A (de)
KR (1) KR20050052663A (de)
CN (1) CN1681939A (de)
AU (1) AU2003259498A1 (de)
CA (1) CA2497434A1 (de)
NO (1) NO20051869L (de)
RU (1) RU2005107701A (de)
WO (1) WO2004027018A2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100934706B1 (ko) * 2006-12-07 2009-12-31 재단법인서울대학교산학협력재단 Ｔｍ４ｓｆ５의 기능을 저해하는 항암물질의 스크리닝 방법및 칼콘계 화합물을 함유하는 항암조성물
US8420080B2 (en) 2007-10-01 2013-04-16 The Trustees Of Columbia University In The City Of New York Methods for treating adult respiratory distress syndrome
CN109112213B (zh) * 2017-06-22 2021-01-12 中国科学院动物研究所 检测黏着斑激酶结构变异体的pcr引物及其检测方法与应用
KR102007450B1 (ko) 2018-05-31 2019-08-05 한국과학기술연구원 대장암 치료제 발굴을 위한 신규 표적 치료 작용점의 스크리닝 방법 및 이를 이용하여 선별한 대장암 치료 예후 바이오마커
KR102408538B1 (ko) * 2020-10-29 2022-06-15 한국과학기술연구원 Fak 활성 억제제를 스크리닝하기 위한 조성물, 키트 및 방법

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998026054A2 (en) * 1996-12-11 1998-06-18 Sugen, Inc. Pyk2 related products and methods
US20010055585A1 (en) * 1997-12-03 2001-12-27 William G. Cance Frnk proteins in the treatment of tumor cells
US6395506B1 (en) * 1991-04-18 2002-05-28 Becton, Dickinson And Company Device for monitoring cells

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6133031A (en) * 1999-08-19 2000-10-17 Isis Pharmaceuticals Inc. Antisense inhibition of focal adhesion kinase expression

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6395506B1 (en) * 1991-04-18 2002-05-28 Becton, Dickinson And Company Device for monitoring cells
WO1998026054A2 (en) * 1996-12-11 1998-06-18 Sugen, Inc. Pyk2 related products and methods
US20010055585A1 (en) * 1997-12-03 2001-12-27 William G. Cance Frnk proteins in the treatment of tumor cells

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
OKTAY M H ET AL: "Assays for kinase activity.", METHODS IN MOLECULAR BIOLOGY (CLIFTON, N.J.) 1999, vol. 129, 1999, pages 51 - 61, XP009067862, ISSN: 1064-3745 *

Also Published As

Publication number Publication date
KR20050052663A (ko) 2005-06-03
CA2497434A1 (en) 2004-04-01
JP2006500022A (ja) 2006-01-05
WO2004027018A2 (en) 2004-04-01
AU2003259498A1 (en) 2004-04-08
EP1546372A2 (de) 2005-06-29
WO2004027018A3 (en) 2004-09-16
RU2005107701A (ru) 2005-08-27
NO20051869D0 (no) 2005-04-18
NO20051869L (no) 2005-06-16
CN1681939A (zh) 2005-10-12

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 20050419

AK Designated contracting states

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Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL LT LV MK

DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20060725

RIC1 Information provided on ipc code assigned before grant

Ipc: C12N 9/12 20060101ALI20060719BHEP

Ipc: G01N 33/68 20060101ALI20060719BHEP

Ipc: G01N 33/50 20060101ALI20060719BHEP

Ipc: G01N 33/573 20060101ALI20060719BHEP

Ipc: C12Q 1/48 20060101AFI20050311BHEP

17Q First examination report despatched

Effective date: 20061207

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20070418