EP1501844A4 - DISChARIDE FOR DRUG DEVELOPMENT - Google Patents

DISChARIDE FOR DRUG DEVELOPMENT

Info

Publication number
EP1501844A4
EP1501844A4 EP20030714557 EP03714557A EP1501844A4 EP 1501844 A4 EP1501844 A4 EP 1501844A4 EP 20030714557 EP20030714557 EP 20030714557 EP 03714557 A EP03714557 A EP 03714557A EP 1501844 A4 EP1501844 A4 EP 1501844A4
Authority
EP
European Patent Office
Prior art keywords
disaccharides
drug discovery
discovery
drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP20030714557
Other languages
German (de)
English (en)
French (fr)
Other versions
EP1501844A1 (en
Inventor
Wim Meutermans
Michael Leo West
George Adamson
Le Giang Thanh
Nicholas Barry Drinnan
Giovani Abbenante
Bernd Becker
Matthias Grathwohl
Premraj Rajaratnam
Gerald Tometzki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alchemia Pty Ltd
Original Assignee
Alchemia Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alchemia Pty Ltd filed Critical Alchemia Pty Ltd
Publication of EP1501844A1 publication Critical patent/EP1501844A1/en
Publication of EP1501844A4 publication Critical patent/EP1501844A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/04—Disaccharides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/02—Monosaccharides
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/12—Libraries containing saccharides or polysaccharides, or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
    • C40B50/14—Solid phase synthesis, i.e. wherein one or more library building blocks are bound to a solid support during library creation; Particular methods of cleavage from the solid support

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Structural Engineering (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Pyrane Compounds (AREA)
EP20030714557 2002-05-03 2003-04-24 DISChARIDE FOR DRUG DEVELOPMENT Withdrawn EP1501844A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AUPS2138A AUPS213802A0 (en) 2002-05-03 2002-05-03 Disaccharides for drug discovery
AUPS213802 2002-05-03
PCT/AU2003/000494 WO2003093286A1 (en) 2002-05-03 2003-04-24 Disaccharides for drug discovery

Publications (2)

Publication Number Publication Date
EP1501844A1 EP1501844A1 (en) 2005-02-02
EP1501844A4 true EP1501844A4 (en) 2010-10-27

Family

ID=3835711

Family Applications (1)

Application Number Title Priority Date Filing Date
EP20030714557 Withdrawn EP1501844A4 (en) 2002-05-03 2003-04-24 DISChARIDE FOR DRUG DEVELOPMENT

Country Status (6)

Country Link
US (2) US7875707B2 (enExample)
EP (1) EP1501844A4 (enExample)
JP (1) JP2005529910A (enExample)
AU (1) AUPS213802A0 (enExample)
CA (1) CA2483622C (enExample)
WO (1) WO2003093286A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002952121A0 (en) 2002-10-17 2002-10-31 Alchemia Limited Novel carbohydrate based anti-bacterials
WO2005033149A1 (en) * 2003-10-02 2005-04-14 New York University Receptor specific binder discovery using intramolecular acyl migration induced dynamic carbohydrate library
WO2009155108A1 (en) 2008-05-30 2009-12-23 Momenta Pharmaceuticals, Inc. Saccharide structures and methods of making and using such structures
CA2756510A1 (en) * 2009-04-15 2010-10-21 Basf Se Process for the preparation of monoethylenically unsaturated glycosylamines
CN105017193B (zh) * 2014-04-22 2018-11-09 江苏先声药业有限公司 一种扎那米韦杂质的制备方法
CA3085356A1 (en) 2017-12-29 2019-07-04 Glycomimetics, Inc. Heterobifunctional inhibitors of e-selectin and galectin-3
CN118373810A (zh) 2018-12-27 2024-07-23 糖模拟物有限公司 抑制c-糖苷的半乳凝素-3
WO2020139962A1 (en) 2018-12-27 2020-07-02 Glycomimetics, Inc. Heterobifunctional inhibitors of e-selectin and galectin-3
CN112010995A (zh) * 2019-05-30 2020-12-01 株式会社大赛璐 壳聚糖衍生物及光学异构体用分离剂

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995003315A2 (en) * 1993-07-21 1995-02-02 Oxford Glycosystems Ltd Saccharides, their synthesis and use

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5326867A (en) * 1992-07-16 1994-07-05 Bristol-Myers Squibb Company Pradimic acids, amides, and pradimicin derivatives
WO1997034623A1 (en) * 1996-03-21 1997-09-25 Transcell Technologies, Inc. Solid phase lipoglycopeptide library, compositions and methods
AU5821998A (en) 1997-01-13 1998-08-03 Scripps Research Institute, The Nucleic acid binders having an hydroxyamine motif
AUPO536797A0 (en) 1997-02-28 1997-03-20 Alchemia Pty Ltd Protected aminosugars
WO1998053813A1 (en) 1997-05-29 1998-12-03 Incara Pharmaceuticals Corp. Carbohydrate scaffold compounds and libraries
US6114309A (en) 1997-11-21 2000-09-05 Incara Research Laboratories Combinatorial library of moenomycin analogs and methods of producing same
AU4665100A (en) 1999-04-27 2000-11-10 Advanced Medicine, Inc. Novel disaccharide antibacterial agents
CN1395579A (zh) 2000-01-13 2003-02-05 阿尔开密亚有限公司 含α－D－GAL(1→3)GAL的寡糖的合成方法
AUPR084400A0 (en) 2000-10-18 2000-11-09 Alchemia Pty Ltd Immunoadjuvant systems
AU2002952121A0 (en) * 2002-10-17 2002-10-31 Alchemia Limited Novel carbohydrate based anti-bacterials

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995003315A2 (en) * 1993-07-21 1995-02-02 Oxford Glycosystems Ltd Saccharides, their synthesis and use

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
J.-C. JACQUINET, PIERRE SINAY: "Synthesis of Blood-Group Substances. 6. Synthesis of O-alpha-L-Fucopyranosyl-(1-2)-O-beta-D-galactopyranosyl-(1-4)-O-[alpha-L-fucopyranosyl-(1-3)]-2-acetamido-2-deoxy-alpha-D-gluyopyranose, the Postulated Lewis d Antigenic Determinant", JOUNRAL OF ORGANIC CHEMISTRY, vol. 42, no. 4, 1977, pages 720 - 724, XP002599813 *
See also references of WO03093286A1 *
ULRIKE SPOHR, MIMI BACH, ROBERT G. SPIRO: "Inhibitors of endo-alpha-mannosidease. Part I. Derivatives of 3-O-(alpha-D-glucopyranosyl)-D-mannopyranose", CANADIAN JOURNAL OF CHEMISTRY, vol. 71, 1993, pages 119 - 1927, XP002599814 *
USUI T ET AL: "Enzymic synthesis of useful chito-oligosaccharides utilizing transglycosylation by chitinolytic enzymes in a buffer containing ammonium sulfate", CARBOHYDRATE RESEARCH, PERGAMON, GB LNKD- DOI:10.1016/0008-6215(90)80046-6, vol. 203, no. 1, 1 August 1990 (1990-08-01), pages 65 - 77, XP026622724, ISSN: 0008-6215, [retrieved on 19900801] *

Also Published As

Publication number Publication date
AUPS213802A0 (en) 2002-06-06
EP1501844A1 (en) 2005-02-02
WO2003093286A1 (en) 2003-11-13
JP2005529910A (ja) 2005-10-06
US20110201794A1 (en) 2011-08-18
CA2483622C (en) 2012-01-03
US20060121530A1 (en) 2006-06-08
US7875707B2 (en) 2011-01-25
CA2483622A1 (en) 2003-11-13

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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18W Application withdrawn

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