EP1495117A4 - Human deubiquitinating protease gene on chromosome 7 and its murine ortholog - Google Patents

Human deubiquitinating protease gene on chromosome 7 and its murine ortholog

Info

Publication number
EP1495117A4
EP1495117A4 EP03723791A EP03723791A EP1495117A4 EP 1495117 A4 EP1495117 A4 EP 1495117A4 EP 03723791 A EP03723791 A EP 03723791A EP 03723791 A EP03723791 A EP 03723791A EP 1495117 A4 EP1495117 A4 EP 1495117A4
Authority
EP
European Patent Office
Prior art keywords
chromosome
protease gene
murine ortholog
deubiquitinating protease
human deubiquitinating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03723791A
Other languages
German (de)
French (fr)
Other versions
EP1495117A2 (en
Inventor
Chang Hahn
Hong Liu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Aventis Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0218518.9A external-priority patent/GB0218518D0/en
Application filed by Aventis Pharmaceuticals Inc filed Critical Aventis Pharmaceuticals Inc
Publication of EP1495117A2 publication Critical patent/EP1495117A2/en
Publication of EP1495117A4 publication Critical patent/EP1495117A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6472—Cysteine endopeptidases (3.4.22)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Analytical Chemistry (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP03723791A 2002-03-22 2003-03-21 Human deubiquitinating protease gene on chromosome 7 and its murine ortholog Withdrawn EP1495117A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US36660102P 2002-03-22 2002-03-22
US366601P 2002-03-22
GB0218518 2002-08-09
GBGB0218518.9A GB0218518D0 (en) 2002-03-22 2002-08-09 Human deubiquitinating protease gene on chromosome 7 and its murine ortholog
PCT/US2003/008590 WO2003083050A2 (en) 2002-03-22 2003-03-21 Human deubiquitinating protease gene on chromosome 7 and its murine ortholog

Publications (2)

Publication Number Publication Date
EP1495117A2 EP1495117A2 (en) 2005-01-12
EP1495117A4 true EP1495117A4 (en) 2005-06-08

Family

ID=28676509

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03723791A Withdrawn EP1495117A4 (en) 2002-03-22 2003-03-21 Human deubiquitinating protease gene on chromosome 7 and its murine ortholog

Country Status (8)

Country Link
EP (1) EP1495117A4 (en)
JP (1) JP2005520567A (en)
AU (1) AU2003230701C1 (en)
BR (1) BR0307759A (en)
CA (1) CA2479647A1 (en)
IL (1) IL164088A0 (en)
MX (1) MXPA04006975A (en)
WO (1) WO2003083050A2 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997006247A2 (en) * 1995-08-09 1997-02-20 Dana Farber Cancer Institute Deubiquitinating enzymes that regulate cell growth
WO2001010903A2 (en) * 1999-08-09 2001-02-15 Incyte Genomics, Inc. Proteases and protease inhibitors
WO2001023589A2 (en) * 1999-09-29 2001-04-05 Millennium Pharmaceuticals, Inc. 23431, a novel human ubiquitin protease

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997006247A2 (en) * 1995-08-09 1997-02-20 Dana Farber Cancer Institute Deubiquitinating enzymes that regulate cell growth
WO2001010903A2 (en) * 1999-08-09 2001-02-15 Incyte Genomics, Inc. Proteases and protease inhibitors
WO2001023589A2 (en) * 1999-09-29 2001-04-05 Millennium Pharmaceuticals, Inc. 23431, a novel human ubiquitin protease

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BAKER R T ET AL: "Identification, Functional Characterization, and Chromosomal Localization of USP15, a Novel Human Ubiquitin-Specific Protease Related to the UNP Oncoprotein, and a Systematic Nomenclature for Human Ubiquitin-Specific Proteases", GENOMICS, ACADEMIC PRESS, SAN DIEGO, US, vol. 59, no. 3, 1 August 1999 (1999-08-01), pages 264 - 274, XP004444843, ISSN: 0888-7543 *
JANS D A ET AL: "SIGNALS MEDIATING NUCLEAR TARGETING AND THEIR REGULATION: APPLICATION IN DRUG DELIVERY", MEDICINAL RESEARCH REVIEWS, NEW YORK, NY, US, vol. 18, no. 4, July 1998 (1998-07-01), pages 189 - 223, XP002922553, ISSN: 0198-6325 *

Also Published As

Publication number Publication date
JP2005520567A (en) 2005-07-14
WO2003083050A2 (en) 2003-10-09
AU2003230701B2 (en) 2008-06-05
AU2003230701A1 (en) 2003-10-13
CA2479647A1 (en) 2003-10-09
WO2003083050A3 (en) 2004-02-26
MXPA04006975A (en) 2004-11-10
BR0307759A (en) 2004-12-21
IL164088A0 (en) 2005-12-18
EP1495117A2 (en) 2005-01-12
AU2003230701C1 (en) 2009-08-27

Similar Documents

Publication Publication Date Title
HK1079995A1 (en) Modified asialo-interferons and uses thereof
IL166377A0 (en) Vrgfr-2 and vgefr-3 inhibitory and anthranylamidpyrimidines
EP1652855A4 (en) Polypeptides having brain -localizing activity and uses thereof
EP1466982A4 (en) Pyroglutamyl peptidase and its gene
PL377770A1 (en) Substituted benzoxazinones and uses thereof
AU2003280084A8 (en) Protein arrays and uses thereof
TWI348914B (en) Human deubiquitinating protease gene on chromosome 7 and its murine ortholog
IL165112A0 (en) Variant integrinpolypeptides and thereof
EP1479762A4 (en) Novel dehydrogenase and gene encoding the same
GB0200941D0 (en) Laryngoscopes and parts thereof
EP1446780A4 (en) Portable alarm system that interfaces with an individual's personal radio
EP1495117A4 (en) Human deubiquitinating protease gene on chromosome 7 and its murine ortholog
AU2003228474A8 (en) Secretory signal sequences and uses thereof
AU2003262744A8 (en) Alpha-amylase assay and uses thereof
EP1484403A4 (en) Gene participating in the synthesis of brassinosteroid
EP1531852A4 (en) Caspase 9 activation and uses therefor
EP1549664A4 (en) Murine ortholog of the human disrupted-in-schizophrenia 1 gene
EP1577322A4 (en) Novel proteins and use thereof
EP1541677A4 (en) Novel proteins and use thereof
AU2003291426A8 (en) Gp64-pseudotyped vectors and uses thereof
AU2003216442A8 (en) Enkurin and uses thereof
AU2003213936A8 (en) Polypeptides from bacteria and uses thereof
AU2003238892A8 (en) Secretory signal sequences and uses thereof
AU2003263751A8 (en) Novel proteins and their uses
HK1041013A1 (en) Aliphatic thermoplastic polyurethanes and use thereof.

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20041022

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL LT LV MK

A4 Supplementary search report drawn up and despatched

Effective date: 20050421

RIC1 Information provided on ipc code assigned before grant

Ipc: 7A 61K 38/48 B

Ipc: 7C 12Q 1/68 B

Ipc: 7C 12Q 1/37 B

Ipc: 7C 12N 15/62 B

Ipc: 7C 12N 15/57 B

Ipc: 7C 12N 9/64 A

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: AVENTIS PHARMACEUTICALS, INC.

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20060912