EP1487965A4 - Compositions minicellulaires et methodes associees - Google Patents

Compositions minicellulaires et methodes associees

Info

Publication number
EP1487965A4
EP1487965A4 EP02747872A EP02747872A EP1487965A4 EP 1487965 A4 EP1487965 A4 EP 1487965A4 EP 02747872 A EP02747872 A EP 02747872A EP 02747872 A EP02747872 A EP 02747872A EP 1487965 A4 EP1487965 A4 EP 1487965A4
Authority
EP
European Patent Office
Prior art keywords
methods
minicell compositions
minicell
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP02747872A
Other languages
German (de)
English (en)
Other versions
EP1487965A2 (fr
Inventor
Roger A Sabbadini
Mark Surber
Neil Berkley
Matthew Giacalone
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vaxiion Therapeutics LLC
Original Assignee
Mpex Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27767433&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EP1487965(A4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US10/154,951 external-priority patent/US20030194798A1/en
Application filed by Mpex Pharmaceuticals Inc filed Critical Mpex Pharmaceuticals Inc
Priority to EP10008869.9A priority Critical patent/EP2272946B9/fr
Priority to EP20110000796 priority patent/EP2390308A1/fr
Publication of EP1487965A2 publication Critical patent/EP1487965A2/fr
Publication of EP1487965A4 publication Critical patent/EP1487965A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/5432—Liposomes or microcapsules
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/60—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances involving radioactive labelled substances

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
EP02747872A 2002-02-25 2002-05-28 Compositions minicellulaires et methodes associees Withdrawn EP1487965A4 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP10008869.9A EP2272946B9 (fr) 2002-02-25 2002-05-28 Compositions et méthodes de minicellules
EP20110000796 EP2390308A1 (fr) 2002-02-25 2002-05-28 Compositions de minicellules et procédés

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US154951 1988-02-10
US35984302P 2002-02-25 2002-02-25
US359843P 2002-02-25
US10/154,951 US20030194798A1 (en) 2001-05-24 2002-05-24 Minicell compositions and methods
PCT/US2002/016877 WO2003072014A2 (fr) 2002-02-25 2002-05-28 Compositions minicellulaires et methodes associees

Related Child Applications (1)

Application Number Title Priority Date Filing Date
EP10008869.9A Division EP2272946B9 (fr) 2002-02-25 2002-05-28 Compositions et méthodes de minicellules

Publications (2)

Publication Number Publication Date
EP1487965A2 EP1487965A2 (fr) 2004-12-22
EP1487965A4 true EP1487965A4 (fr) 2006-11-15

Family

ID=27767433

Family Applications (3)

Application Number Title Priority Date Filing Date
EP02747872A Withdrawn EP1487965A4 (fr) 2002-02-25 2002-05-28 Compositions minicellulaires et methodes associees
EP20110000796 Withdrawn EP2390308A1 (fr) 2002-02-25 2002-05-28 Compositions de minicellules et procédés
EP10008869.9A Revoked EP2272946B9 (fr) 2002-02-25 2002-05-28 Compositions et méthodes de minicellules

Family Applications After (2)

Application Number Title Priority Date Filing Date
EP20110000796 Withdrawn EP2390308A1 (fr) 2002-02-25 2002-05-28 Compositions de minicellules et procédés
EP10008869.9A Revoked EP2272946B9 (fr) 2002-02-25 2002-05-28 Compositions et méthodes de minicellules

Country Status (6)

Country Link
EP (3) EP1487965A4 (fr)
AU (1) AU2002318168B2 (fr)
CA (1) CA2517027A1 (fr)
ES (1) ES2541351T3 (fr)
HK (1) HK1153229A1 (fr)
WO (1) WO2003072014A2 (fr)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
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US20030194798A1 (en) 2001-05-24 2003-10-16 Surber Mark W. Minicell compositions and methods
US7396822B2 (en) 2001-05-24 2008-07-08 Vaxiion Therapeutics, Inc. Immunogenic minicells and methods of use
JP4458846B2 (ja) * 2001-10-15 2010-04-28 エンジーンアイシー モレキュラー デリバリー ピーティーワイ リミテッド ｉｎｖｉｔｒｏおよびｉｎｖｉｖｏにおけるＤＮＡ導入および遺伝子療法のためのベクターとしての完全なミニ細胞
US7611885B2 (en) 2003-06-24 2009-11-03 Engeneic Molecular Delivery Pty, Ltd. Pharmaceutically compatible method for purifying intact bacterial minicells
ATE501735T1 (de) 2003-12-09 2011-04-15 Engeneic Molecular Delivery Pty Ltd Gezielte genabgabe an nicht-phagozytische säugetierzellen über bakteriell erhaltene intakte minizellen
US8772013B2 (en) 2004-02-02 2014-07-08 Engeneic Molecular Delivery Pty Ltd Methods for targeted in vitro and in vivo drug delivery to mammalian cells via bacterially derived intact minicells
SG169373A1 (en) * 2004-02-02 2011-03-30 Engeneic Molecular Delivery Pty Ltd Compositions and methods for targeted in vitro and in vivo drug delivery to mammalian cells via bacterially derived intact minicells
JP4114075B2 (ja) * 2004-02-16 2008-07-09 ヒューマン・メタボローム・テクノロジーズ株式会社 遺伝子産物の機能同定方法及び結合物質同定方法
US8055347B2 (en) 2005-08-19 2011-11-08 Brainsgate Ltd. Stimulation for treating brain events and other conditions
US8010189B2 (en) 2004-02-20 2011-08-30 Brainsgate Ltd. SPG stimulation for treating complications of subarachnoid hemorrhage
US9233245B2 (en) 2004-02-20 2016-01-12 Brainsgate Ltd. SPG stimulation
WO2006055024A2 (fr) * 2004-04-05 2006-05-26 Vaxiion Therapeutics, Inc. Minicellules employees comme vaccins
JP4965447B2 (ja) 2004-08-26 2012-07-04 エンジーンアイシー モレキュラー デリバリー ピーティーワイ リミテッド 細菌由来のインタクトなミニセルを介した哺乳動物細胞への機能性核酸の送達
US9878043B2 (en) 2006-06-23 2018-01-30 Engeneic Molecular Delivery Pty Ltd Targeted delivery of drugs, therapeutic nucleic acids and functional nucleic acids to mammalian cells via intact killed bacterial cells
EP2675474B1 (fr) 2011-02-15 2019-01-16 Vaxiion Therapeutics, LLC Compositions thérapeutiques et procédés d'administration ciblée de molécules bioactives par des minicellules bactériennes basée sur des molécules de ciblage contenant un fragment fc et des anticorps
US20140342932A1 (en) * 2011-09-23 2014-11-20 Merck Sharp & Dohme Corp. Functional cell surface display of ligands for the insulin and/or insulin growth factor 1 receptor and applications thereof
EP2878335B1 (fr) 2013-11-10 2018-01-03 Brainsgate Ltd. Implant et système d'implantation pour stimulateur neural
RU2577138C1 (ru) * 2014-11-25 2016-03-10 Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) Способ получения рекомбинантного белка sav-rgd
EP3093043B1 (fr) 2015-05-13 2018-11-14 Brainsgate Ltd. Implant et système de distribution pour stimulateur neural
US11649265B2 (en) 2017-04-28 2023-05-16 Agrospheres, Inc. Compositions and methods for the encapsulation and scalable delivery of agrochemicals
CA3073449A1 (fr) 2017-09-25 2019-03-28 Agrospheres, Inc. Compositions et procedes de production et d'administration evolutive de produits biologiques
WO2020141495A1 (fr) * 2019-01-04 2020-07-09 Engeneic Molecular Delivery Pty Ltd Antigènes glycolipidiques encapsulés pour le traitement de maladies néoplasiques
CN110669811A (zh) * 2019-10-21 2020-01-10 天津大学 一种提高表面活性素产量的方法
JP2023517051A (ja) * 2020-03-06 2023-04-21 エンドリティクス テクノロジー インコーポレイテッド 細胞内細菌を治療するための組成物及び方法
CN116087504B (zh) * 2023-02-24 2023-08-15 上海碧云天生物技术有限公司 免疫磁珠保护液、其制备方法及应用

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EP2272946A2 (fr) 2011-01-12
EP2272946A3 (fr) 2011-07-27
CA2517027A1 (fr) 2003-09-04
AU2002318168B2 (en) 2007-12-13
ES2541351T3 (es) 2015-07-17
WO2003072014B1 (fr) 2004-04-22
WO2003072014A2 (fr) 2003-09-04
AU2002318168A1 (en) 2003-09-09
HK1153229A1 (en) 2012-03-23
EP1487965A2 (fr) 2004-12-22
WO2003072014A3 (fr) 2004-02-12
EP2272946B1 (fr) 2015-04-08
EP2390308A1 (fr) 2011-11-30

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