EP1478433A4 - Verbindungselement für ein medikamentenabgabesystem in einem cochlear-implantat - Google Patents

Verbindungselement für ein medikamentenabgabesystem in einem cochlear-implantat

Info

Publication number
EP1478433A4
EP1478433A4 EP03702212A EP03702212A EP1478433A4 EP 1478433 A4 EP1478433 A4 EP 1478433A4 EP 03702212 A EP03702212 A EP 03702212A EP 03702212 A EP03702212 A EP 03702212A EP 1478433 A4 EP1478433 A4 EP 1478433A4
Authority
EP
European Patent Office
Prior art keywords
cochlear implant
connector
delivery system
drug delivery
chamber
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP03702212A
Other languages
English (en)
French (fr)
Other versions
EP1478433B1 (de
EP1478433A1 (de
Inventor
Thomas Lenarz
Gerrit Paasche
Timo Stoever
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cochlear Ltd
Original Assignee
Cochlear Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cochlear Ltd filed Critical Cochlear Ltd
Publication of EP1478433A1 publication Critical patent/EP1478433A1/de
Publication of EP1478433A4 publication Critical patent/EP1478433A4/de
Application granted granted Critical
Publication of EP1478433B1 publication Critical patent/EP1478433B1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0526—Head electrodes
    • A61N1/0541—Cochlear electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F11/00—Methods or devices for treatment of the ears or hearing sense; Non-electric hearing aids; Methods or devices for enabling ear patients to achieve auditory perception through physiological senses other than hearing sense; Protective devices for the ears, carried on the body or in the hand
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0043—Catheters; Hollow probes characterised by structural features
    • A61M2025/0063—Catheters; Hollow probes characterised by structural features having means, e.g. stylets, mandrils, rods or wires to reinforce or adjust temporarily the stiffness, column strength or pushability of catheters which are already inserted into the human body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/06—Head
    • A61M2210/0662—Ears
    • A61M2210/0668—Middle ear
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14276—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36036—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of the outer, middle or inner ear
    • A61N1/36038—Cochlear stimulation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Otolaryngology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Acoustics & Sound (AREA)
  • Biophysics (AREA)
  • Psychology (AREA)
  • Vascular Medicine (AREA)
  • Prostheses (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Electrotherapy Devices (AREA)
EP03702212A 2002-02-28 2003-02-28 Verbindungselement für ein medikamentenabgabesystem in einem cochlear-implantat Expired - Lifetime EP1478433B1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AUPS081502 2002-02-28
AUPS0815A AUPS081502A0 (en) 2002-02-28 2002-02-28 Connector for drug delivery system
PCT/AU2003/000248 WO2003072193A1 (en) 2002-02-28 2003-02-28 Connector for drug delivery system in cochlear implant

Publications (3)

Publication Number Publication Date
EP1478433A1 EP1478433A1 (de) 2004-11-24
EP1478433A4 true EP1478433A4 (de) 2006-07-26
EP1478433B1 EP1478433B1 (de) 2009-11-04

Family

ID=3834414

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03702212A Expired - Lifetime EP1478433B1 (de) 2002-02-28 2003-02-28 Verbindungselement für ein medikamentenabgabesystem in einem cochlear-implantat

Country Status (8)

Country Link
US (1) US20050256560A1 (de)
EP (1) EP1478433B1 (de)
JP (1) JP2005518845A (de)
AT (1) ATE447425T1 (de)
AU (2) AUPS081502A0 (de)
CA (1) CA2477148A1 (de)
DE (1) DE60329901D1 (de)
WO (1) WO2003072193A1 (de)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9089450B2 (en) * 2000-11-14 2015-07-28 Cochlear Limited Implantatable component having an accessible lumen and a drug release capsule for introduction into same
AUPR148400A0 (en) 2000-11-14 2000-12-07 Cochlear Limited Apparatus for delivery of pharmaceuticals to the cochlea
US20070088335A1 (en) * 2001-10-24 2007-04-19 Med-El Elektromedizinische Geraete Gmbh Implantable neuro-stimulation electrode with fluid reservoir
AUPR879201A0 (en) * 2001-11-09 2001-12-06 Cochlear Limited Subthreshold stimulation of a cochlea
US20050171579A1 (en) * 2001-11-09 2005-08-04 Claudia Tasche Stimulating device
US20100030130A1 (en) * 2001-11-09 2010-02-04 Cochlear Limited Pharmaceutical intervention for modulation of neural plasticity
US20100030301A1 (en) * 2001-11-09 2010-02-04 Cochlear Limited Electrical stimulation for modulation of neural plasticity
WO2004050056A1 (en) * 2002-11-29 2004-06-17 Cochlear Limited Cochlear implant drug delivery device
US7501630B2 (en) * 2003-02-21 2009-03-10 Koninklijke Philips Electronics N.V. Gas measurement system
EP1765459B1 (de) 2004-06-15 2018-11-28 Cochlear Limited Automatischer nachweis der schwelle einer evozierten nervenreaktion
US20060264897A1 (en) * 2005-01-24 2006-11-23 Neurosystec Corporation Apparatus and method for delivering therapeutic and/or other agents to the inner ear and to other tissues
AU2006222983B2 (en) * 2005-03-15 2012-08-16 The Regents Of The University Of California Method and system for modulating energy expenditure and neurotrophic factors
US20110077579A1 (en) * 2005-03-24 2011-03-31 Harrison William V Cochlear implant with localized fluid transport
US9265933B2 (en) 2005-09-08 2016-02-23 Massachusetts Eye And Ear Infirmary Cochlear implants containing biological cells and uses thereof
EP1933932A4 (de) * 2005-09-21 2010-08-25 Univ Ohio State Elektrische stimulierung des zell- und gewebewachstums mit elektroden mit zwei- und dreidimensionalem muster
DE102006006263B3 (de) * 2006-02-10 2007-11-22 Universität Rostock Cochleaelektrode
ATE497797T1 (de) 2006-03-14 2011-02-15 Univ Southern California Mems-vorrichtung zur wirkstofffreisetzung
US8267905B2 (en) * 2006-05-01 2012-09-18 Neurosystec Corporation Apparatus and method for delivery of therapeutic and other types of agents
US7803148B2 (en) 2006-06-09 2010-09-28 Neurosystec Corporation Flow-induced delivery from a drug mass
US8133215B2 (en) 2007-08-13 2012-03-13 Cochlear Limited Independently-manufactured drug delivery module and corresponding receptacle in an implantable medical device
US8271101B2 (en) 2007-08-29 2012-09-18 Advanced Bionics Modular drug delivery system for minimizing trauma during and after insertion of a cochlear lead
US8190271B2 (en) 2007-08-29 2012-05-29 Advanced Bionics, Llc Minimizing trauma during and after insertion of a cochlear lead
EP2047884B1 (de) * 2007-10-09 2018-04-04 Cochlear Limited Implantierbare Komponente mit einem zugänglichen Lumen und eine Arzneimittelabgabekapsel zur Einführung in den Lumen
US20090312769A1 (en) * 2007-12-10 2009-12-17 Cochlear Limited Stylet for stimulating medical implants
EP2242464B2 (de) 2007-12-20 2017-03-01 University Of Southern California Vorrichtung zur abgabe von therapeutika
US9333297B2 (en) 2008-05-08 2016-05-10 Minipumps, Llc Drug-delivery pump with intelligent control
WO2009137780A2 (en) 2008-05-08 2009-11-12 Replenish Pumps, Llc Implantable pumps and cannulas therefor
EP2323716B1 (de) 2008-05-08 2015-03-04 MiniPumps, LLC Arzneiabgabepumpen
US20110245235A1 (en) * 2008-10-10 2011-10-06 Hanley Peter J Systems, Methods, and Devices for Rehabilitation of Auditory System Disorders Using Pharmaceutical Agents and Auditory Devices
EP3488837A1 (de) * 2009-07-15 2019-05-29 NewSouth Innovations Pty Limited Elektroporationsvorrichtung zur verabreichung von mitteln in die hörschnecke
WO2011022484A1 (en) 2009-08-18 2011-02-24 Replenish Pumps. Llc Electrolytic drug-delivery pump with adaptive control
US20110137393A1 (en) * 2009-12-03 2011-06-09 Pawsey Nicholas C Stiffiner having an enlarged bombous distal end region and corresponding cochlear implant stimulating assembly
US20110288500A1 (en) * 2010-05-24 2011-11-24 Fysh Dadd Drug-delivery element for an elongate implantable medical device component
US8617097B2 (en) 2010-05-24 2013-12-31 Cochlear Limited Drug-delivery accessory for an implantable medical device
US8585648B2 (en) 2010-07-19 2013-11-19 Minipumps, Llc Catheter drug pump
US20120245534A1 (en) * 2011-03-25 2012-09-27 Med-El Elektromedizinische Geraete Gmbh Drug Delivery Electrode with Temporary Fill Tube
AU2013232514A1 (en) * 2012-03-15 2014-09-04 Med-El Elektromedizinische Geraete Gmbh Accessory device for inner ear drug delivery
WO2019058333A2 (en) * 2017-09-22 2019-03-28 Cochlear Limited BIOACTIVE AGENT DISTRIBUTION
WO2022224055A1 (en) * 2021-04-20 2022-10-27 Cochlear Limited Body chamber therapeutic substance delivery

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5697951A (en) * 1996-04-25 1997-12-16 Medtronic, Inc. Implantable stimulation and drug infusion techniques
US5929041A (en) * 1996-02-23 1999-07-27 Amgen Inc. Method for preventing and treating sensorineural hearing loss and vestibular disorders using glial cell line-derived neurotrophic factor(GDNF) protein product
WO2000071063A1 (en) * 1999-05-21 2000-11-30 Cochlear Limited A cochlear implant electrode array
US6309410B1 (en) * 1998-08-26 2001-10-30 Advanced Bionics Corporation Cochlear electrode with drug delivery channel and method of making same

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4357497A (en) * 1979-09-24 1982-11-02 Hochmair Ingeborg System for enhancing auditory stimulation and the like
US4532930A (en) * 1983-04-11 1985-08-06 Commonwealth Of Australia, Dept. Of Science & Technology Cochlear implant system for an auditory prosthesis
US4819662A (en) * 1987-10-26 1989-04-11 Cardiac Pacemakers, Inc. Cardiac electrode with drug delivery capabilities
US4994069A (en) * 1988-11-02 1991-02-19 Target Therapeutics Vaso-occlusion coil and method
US5458631A (en) * 1989-01-06 1995-10-17 Xavier; Ravi Implantable catheter with electrical pulse nerve stimulators and drug delivery system
EP0412191B1 (de) * 1989-08-09 1993-02-03 Siemens Aktiengesellschaft Implantierbarer Injektionskörper
US5447533A (en) * 1992-09-03 1995-09-05 Pacesetter, Inc. Implantable stimulation lead having an advanceable therapeutic drug delivery system
US5496362A (en) * 1992-11-24 1996-03-05 Cardiac Pacemakers, Inc. Implantable conformal coil patch electrode with multiple conductive elements for cardioversion and defibrillation
AU702746B2 (en) * 1995-09-20 1999-03-04 Cochlear Limited Bioresorbable polymer use in cochlear and other implants
US5755474A (en) * 1996-12-05 1998-05-26 Illinois Tool Works Inc. Dual size cup carrier
US5975085A (en) * 1997-05-01 1999-11-02 Medtronic, Inc. Method of treating schizophrenia by brain stimulation and drug infusion
US6038484A (en) * 1997-09-02 2000-03-14 Advanced Bionics Corporation Cochlear electrode with modiolar-hugging system including a flexible positioner
US6125302A (en) * 1997-09-02 2000-09-26 Advanced Bionics Corporation Precurved modiolar-hugging cochlear electrode
US6078841A (en) * 1998-03-27 2000-06-20 Advanced Bionics Corporation Flexible positioner for use with implantable cochlear electrode array
US6304787B1 (en) * 1998-08-26 2001-10-16 Advanced Bionics Corporation Cochlear electrode array having current-focusing and tissue-treating features
US6163729A (en) * 1998-08-26 2000-12-19 Advanced Bionics Corporation Method of positioning an implantable cochlear electrode array within a cochlea
US6038482A (en) * 1998-10-30 2000-03-14 Pacesetter, Inc. Open bore electrode with a tiered drug therapy delivery system
US6398758B1 (en) * 1999-02-16 2002-06-04 Stephen C. Jacobsen Medicament delivery system
US6259951B1 (en) * 1999-05-14 2001-07-10 Advanced Bionics Corporation Implantable cochlear stimulator system incorporating combination electrode/transducer
EP1233810B1 (de) * 2000-10-17 2010-04-21 Cochlear Limited Einführungsvorrichtung für kochleares elektrodenfeldimplantat
AUPR148400A0 (en) 2000-11-14 2000-12-07 Cochlear Limited Apparatus for delivery of pharmaceuticals to the cochlea
US6567704B2 (en) * 2000-12-20 2003-05-20 Medtronic, Inc. Medical electrical lead and method of use
WO2003034960A1 (en) * 2001-10-24 2003-05-01 Med-El Elektromedizinische Geräte Ges.m.b.H. Implantable fluid delivery apparatuses and implantable electrode

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5929041A (en) * 1996-02-23 1999-07-27 Amgen Inc. Method for preventing and treating sensorineural hearing loss and vestibular disorders using glial cell line-derived neurotrophic factor(GDNF) protein product
US5697951A (en) * 1996-04-25 1997-12-16 Medtronic, Inc. Implantable stimulation and drug infusion techniques
US6309410B1 (en) * 1998-08-26 2001-10-30 Advanced Bionics Corporation Cochlear electrode with drug delivery channel and method of making same
WO2000071063A1 (en) * 1999-05-21 2000-11-30 Cochlear Limited A cochlear implant electrode array

Also Published As

Publication number Publication date
DE60329901D1 (de) 2009-12-17
EP1478433B1 (de) 2009-11-04
AU2003205441A1 (en) 2003-09-09
WO2003072193A1 (en) 2003-09-04
ATE447425T1 (de) 2009-11-15
US20050256560A1 (en) 2005-11-17
JP2005518845A (ja) 2005-06-30
AUPS081502A0 (en) 2002-03-21
CA2477148A1 (en) 2003-09-04
EP1478433A1 (de) 2004-11-24

Similar Documents

Publication Publication Date Title
EP1478433A4 (de) Verbindungselement für ein medikamentenabgabesystem in einem cochlear-implantat
WO2023014914A3 (en) Medication delivery pump having glucose sensor
WO2002068018A3 (en) Integrated medication delivery system
EP0714316A4 (de) Implantierbare vorrichtung zur arzneiabgabe
AU2002360111A1 (en) Device for medicine delivery by intraocular iontophoresis or electroporation
WO2003066123A3 (en) Microinfusion device
EP1340408A4 (de) Vorrichtung zum abliefern von pharmazeutika an das innenohr
IL164394A0 (en) Transcutaneous fluid delivery system
RU2009106178A (ru) Имплантируемое устройство и способ доставки текучего лекарственного препарата в ткань
MX2009011953A (es) Canula y dispositivo de suministro.
AU2003243305A8 (en) Implantable medication delivery device
EP1482914A4 (de) Implantierbares arzneimittelabgabesystem
GB2389791B (en) Implantable drug delivery pump
NZ527157A (en) Compositions for delivering bisphosphonates
WO2004073765A3 (en) Drug delivery device and syringe for filling the same
MXPA04001505A (es) Jeringa alargada.
EP2407203A3 (de) Festes Therapeutikum zur Verwendung in einer implantierbaren Arzneimittelabgabevorrichtung
GB2399020A (en) Subretinal implantation device and surgical cannulas for use therewith
EP1622592A4 (de) Implantierbare arzneimittelabgabevorrichtung unter verwendung eines druckreglers
IL165830A0 (en) Targeting system comprising uniformly-sized nanoparticles with at least one polymer and at least onepositively charged polysaccharide and preparation method thereof
NZ332852A (en) Veterinary medicament delivery system in the form of a gun
ZA200401217B (en) Zero order controlled drug delivery system.
ZA200000610B (en) Micro-osmotic controlled drug delivery systems.
MXPA03007124A (es) Sistemas para el suministro de farmaco con objetivo anti-tumor.
WO2003106640A3 (en) CELL TARGETING METHODS AND COMPOSITIONS

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20040830

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT SE SI SK TR

AX Request for extension of the european patent

Extension state: AL LT LV MK RO

A4 Supplementary search report drawn up and despatched

Effective date: 20060623

RIC1 Information provided on ipc code assigned before grant

Ipc: A61N 1/36 20060101ALI20060619BHEP

Ipc: A61N 1/05 20060101AFI20030906BHEP

Ipc: H04R 25/00 20060101ALI20060619BHEP

17Q First examination report despatched

Effective date: 20080807

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

GRAS Grant fee paid

Free format text: ORIGINAL CODE: EPIDOSNIGR3

GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

AK Designated contracting states

Kind code of ref document: B1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT SE SI SK TR

REG Reference to a national code

Ref country code: GB

Ref legal event code: FG4D

REG Reference to a national code

Ref country code: CH

Ref legal event code: EP

REG Reference to a national code

Ref country code: IE

Ref legal event code: FG4D

REF Corresponds to:

Ref document number: 60329901

Country of ref document: DE

Date of ref document: 20091217

Kind code of ref document: P

NLV1 Nl: lapsed or annulled due to failure to fulfill the requirements of art. 29p and 29m of the patents act
PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20091104

Ref country code: PT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20100304

Ref country code: FI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20091104

Ref country code: ES

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20100215

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20091104

Ref country code: CY

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20091104

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: BE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20091104

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: DK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20091104

Ref country code: EE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20091104

Ref country code: BG

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20100204

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20091104

Ref country code: CZ

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20091104

PLBE No opposition filed within time limit

Free format text: ORIGINAL CODE: 0009261

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT

REG Reference to a national code

Ref country code: CH

Ref legal event code: PL

26N No opposition filed

Effective date: 20100805

GBPC Gb: european patent ceased through non-payment of renewal fee

Effective date: 20100228

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MC

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20100301

Ref country code: LI

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20100228

Ref country code: GR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20100205

Ref country code: CH

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20100228

REG Reference to a national code

Ref country code: FR

Ref legal event code: ST

Effective date: 20101029

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20100228

Ref country code: FR

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20100301

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20091104

Ref country code: GB

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20100228

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: AT

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20100228

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LU

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20100228

Ref country code: HU

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20100505

Ref country code: NL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20091104

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: TR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20091104

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: DE

Payment date: 20130220

Year of fee payment: 11

REG Reference to a national code

Ref country code: DE

Ref legal event code: R119

Ref document number: 60329901

Country of ref document: DE

REG Reference to a national code

Ref country code: DE

Ref legal event code: R119

Ref document number: 60329901

Country of ref document: DE

Effective date: 20140902

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: DE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20140902