EP1464673A3 - polyanhydrides contenant des produits de dégradation biologiquement actifs - Google Patents
polyanhydrides contenant des produits de dégradation biologiquement actifs Download PDFInfo
- Publication number
- EP1464673A3 EP1464673A3 EP04007101A EP04007101A EP1464673A3 EP 1464673 A3 EP1464673 A3 EP 1464673A3 EP 04007101 A EP04007101 A EP 04007101A EP 04007101 A EP04007101 A EP 04007101A EP 1464673 A3 EP1464673 A3 EP 1464673A3
- Authority
- EP
- European Patent Office
- Prior art keywords
- polyanhydrides
- biologically active
- degradation products
- active degradation
- degrade
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/85—Polyesters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G67/00—Macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing oxygen or oxygen and carbon, not provided for in groups C08G2/00 - C08G65/00
- C08G67/04—Polyanhydrides
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L73/00—Compositions of macromolecular compounds obtained by reactions forming a linkage containing oxygen or oxygen and carbon in the main chain, not provided for in groups C08L59/00 - C08L71/00; Compositions of derivatives of such polymers
- C08L73/02—Polyanhydrides
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L77/00—Compositions of polyamides obtained by reactions forming a carboxylic amide link in the main chain; Compositions of derivatives of such polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/006—Antidandruff preparations
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Polymers & Plastics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Birds (AREA)
- Emergency Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Ophthalmology & Optometry (AREA)
- Transplantation (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Virology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Anti-Oxidant Or Stabilizer Compositions (AREA)
- Polyesters Or Polycarbonates (AREA)
- Biological Depolymerization Polymers (AREA)
- Medicinal Preparation (AREA)
- Polyethers (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US422294 | 1999-10-21 | ||
US09/422,294 US6468519B1 (en) | 1997-09-10 | 1999-10-21 | Polyanhydrides with biologically active degradation products |
EP00968928A EP1246627B1 (fr) | 1999-10-21 | 2000-10-11 | Polyanhydrides contenant des produits de degradation biologiquement actifs |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP00968928A Division EP1246627B1 (fr) | 1999-10-21 | 2000-10-11 | Polyanhydrides contenant des produits de degradation biologiquement actifs |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1464673A2 EP1464673A2 (fr) | 2004-10-06 |
EP1464673A3 true EP1464673A3 (fr) | 2007-12-19 |
Family
ID=23674230
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP04007101A Withdrawn EP1464673A3 (fr) | 1999-10-21 | 2000-10-11 | polyanhydrides contenant des produits de dégradation biologiquement actifs |
EP00968928A Expired - Lifetime EP1246627B1 (fr) | 1999-10-21 | 2000-10-11 | Polyanhydrides contenant des produits de degradation biologiquement actifs |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP00968928A Expired - Lifetime EP1246627B1 (fr) | 1999-10-21 | 2000-10-11 | Polyanhydrides contenant des produits de degradation biologiquement actifs |
Country Status (9)
Country | Link |
---|---|
US (2) | US6468519B1 (fr) |
EP (2) | EP1464673A3 (fr) |
JP (1) | JP2003511550A (fr) |
AT (1) | ATE314078T1 (fr) |
AU (1) | AU7877100A (fr) |
CA (1) | CA2387558A1 (fr) |
DE (1) | DE60025272D1 (fr) |
MX (1) | MXPA02003890A (fr) |
WO (1) | WO2001028492A2 (fr) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6486214B1 (en) * | 1997-09-10 | 2002-11-26 | Rutgers, The State University Of New Jersey | Polyanhydride linkers for production of drug polymers and drug polymer compositions produced thereby |
US7122615B1 (en) * | 1998-09-10 | 2006-10-17 | Rutgers, The State University Of New Jersey | Polyanhydrides with therapeutically useful degradation products |
US6468519B1 (en) * | 1997-09-10 | 2002-10-22 | Rutgers, The State University Of New Jersey | Polyanhydrides with biologically active degradation products |
US7985415B2 (en) * | 1997-09-10 | 2011-07-26 | Rutgers, The State University Of New Jersey | Medical devices employing novel polymers |
US20040038948A1 (en) | 1999-12-07 | 2004-02-26 | Uhrich Kathryn E. | Therapeutic compositions and methods |
AU1956501A (en) * | 1999-12-07 | 2001-06-18 | Rutgers, The State University Of New Jersey | Therapeutic compositions and methods |
US6527801B1 (en) | 2000-04-13 | 2003-03-04 | Advanced Cardiovascular Systems, Inc. | Biodegradable drug delivery material for stent |
US6602915B2 (en) | 2000-07-27 | 2003-08-05 | Rutgers, The State University Of New Jersey | Therapeutic azo-compounds for drug delivery |
CA2417389C (fr) * | 2000-07-27 | 2012-05-29 | Rutgers, The State University | Polyesters et polyamides therapeutiques |
AU2002357762A1 (en) * | 2001-11-23 | 2003-06-10 | Theodore James Anastasion | Improved synthesis of polyanhyrides |
WO2004006863A2 (fr) * | 2002-07-17 | 2004-01-22 | Rutgers, The State University | Dispositifs therapeutiques pour croissance cellulaire structuree |
US6932930B2 (en) | 2003-03-10 | 2005-08-23 | Synecor, Llc | Intraluminal prostheses having polymeric material with selectively modified crystallinity and methods of making same |
US9445901B2 (en) * | 2003-03-12 | 2016-09-20 | Deger C. Tunc | Prosthesis with sustained release analgesic |
CA2525631C (fr) * | 2003-05-13 | 2012-12-18 | Medtronic, Inc. | Materiaux pouvant etre traites a l'humidite pour la delivrance d'agents, procedes, et dispositifs medicaux |
US20050249697A1 (en) * | 2003-09-24 | 2005-11-10 | Uhrich Kathryn E | Compositions and methods for the inhibition of bone growth and resorption |
US8352712B2 (en) * | 2004-05-06 | 2013-01-08 | International Business Machines Corporation | Method and system for specualtively sending processor-issued store operations to a store queue with full signal asserted |
CA2467321A1 (fr) * | 2004-05-14 | 2005-11-14 | Paul J. Santerre | Agents de couplage polymeres et polymeres ayant une activite pharmaceutique produits a partir de ceux-ci |
WO2005110485A1 (fr) * | 2004-05-14 | 2005-11-24 | Interface Biologics Inc. | Agents de couplage polymeres et polymeres pharmaceutiquement actifs obtenus a partir desdits agents |
US7858077B2 (en) * | 2005-01-28 | 2010-12-28 | Bezwada Biomedical Llc | Functionalized phenolic esters and amides and polymers therefrom |
US7691364B2 (en) * | 2005-01-28 | 2010-04-06 | Bezwada Biomedical, Llc | Functionalized drugs and polymers derived therefrom |
US20060193891A1 (en) | 2005-02-25 | 2006-08-31 | Robert Richard | Medical devices and therapeutic delivery devices composed of bioabsorbable polymers produced at room temperature, method of making the devices, and a system for making the devices |
US8263060B2 (en) * | 2005-05-23 | 2012-09-11 | Rutgers, The State University Of New Jersey | Fast degrading polymers |
US8318973B2 (en) * | 2005-10-21 | 2012-11-27 | Bezwada Biomedical, Llc | Functionalized sinapic acid and methyl sinapate |
US8007526B2 (en) | 2005-12-01 | 2011-08-30 | Bezwada Biomedical, Llc | Difunctionalized aromatic compounds and polymers therefrom |
US7935843B2 (en) * | 2005-12-09 | 2011-05-03 | Bezwada Biomedical, Llc | Functionalized diphenolics and absorbable polymers therefrom |
US9603941B2 (en) * | 2006-01-24 | 2017-03-28 | Minghui Chai | Method of preparing dendritic drugs |
US20070225472A1 (en) * | 2006-03-23 | 2007-09-27 | Varshney Sunil K | Polyanhydride polymers and their uses in biomedical devices |
AU2007256626A1 (en) * | 2006-06-06 | 2007-12-13 | Rutgers, The State University Of New Jersey | Iodinated polymers |
EP2102144A4 (fr) | 2006-09-13 | 2011-03-23 | Univ Rutgers | Agents actifs et oligomères et polymères de ceux-ci |
JP2010507668A (ja) * | 2006-10-23 | 2010-03-11 | バイオアブソーバブル セラピューティクス, インコーポレイテッド | 治療担体を有する薬物放出組成物 |
WO2008057501A2 (fr) * | 2006-11-06 | 2008-05-15 | Whitehead Institute | Compositions immunomodulatrices et leurs procédés d'utilisation |
US9457047B2 (en) | 2006-11-06 | 2016-10-04 | Whitehead Institute | Immunomodulating compositions and methods of use thereof |
US8747832B2 (en) * | 2007-04-12 | 2014-06-10 | Rutgers, The State University Of New Jersey | Biodegradable polyanhydrides with natural bioactive molecules |
US8217134B2 (en) | 2007-08-30 | 2012-07-10 | Bezwada Biomedical, Llc | Controlled release of biologically active compounds |
US8026285B2 (en) | 2007-09-04 | 2011-09-27 | Bezwada Biomedical, Llc | Control release of biologically active compounds from multi-armed oligomers |
US8048980B2 (en) * | 2007-09-17 | 2011-11-01 | Bezwada Biomedical, Llc | Hydrolysable linkers and cross-linkers for absorbable polymers |
WO2010148104A2 (fr) * | 2009-06-16 | 2010-12-23 | L'oreal S.A. | Compositions topiques contenant un polymère pour libérer au moins un composé d'acide salicylique |
WO2010148101A2 (fr) * | 2009-06-16 | 2010-12-23 | L'oreal S.A. | Compositions topiques contenant un polymère pour libérer au moins un composé d'acide salicylique |
US8741317B2 (en) | 2010-08-19 | 2014-06-03 | Rutgers, The State University Of New Jersey | Slow-degrading polymers comprising salicylic acid for undelayed and sustained drug delivery |
US9144579B2 (en) | 2012-08-17 | 2015-09-29 | Rutgers, The State University Of New Jersey | Polyesters and methods of use thereof |
US20140120057A1 (en) | 2012-10-25 | 2014-05-01 | Rutgers, The State University Of New Jersey | Polymers and methods thereof for wound healing |
US9387250B2 (en) | 2013-03-15 | 2016-07-12 | Rutgers, The State University Of New Jersey | Therapeutic compositions for bone repair |
US9862672B2 (en) | 2013-05-29 | 2018-01-09 | Rutgers, The State University Of New Jersey | Antioxidant-based poly(anhydride-esters) |
US10023521B2 (en) | 2014-06-13 | 2018-07-17 | Rutgers, The State University Of New Jersey | Process and intermediates for preparing poly(anhydride-esters) |
US10543162B2 (en) | 2015-04-10 | 2020-01-28 | Rutgers, The State University Of New Jersey | Kojic acid polymers |
AU2019214347B2 (en) | 2018-02-02 | 2023-09-28 | Ripple Therapeutics Corporation | Glass formulations comprising steroid dimers and uses thereof |
CA3176134A1 (fr) | 2020-05-01 | 2021-11-04 | Ripple Therapeutics Corporation | Compositions heterodimeres et methodes pour le traitement de troubles oculaires |
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EP0498283A2 (fr) * | 1991-02-04 | 1992-08-12 | General Electric Company | Copolymères d'acides dicarboxyliques et d'acides salicyliques |
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- 2000-10-11 DE DE60025272T patent/DE60025272D1/de not_active Expired - Lifetime
- 2000-10-11 EP EP04007101A patent/EP1464673A3/fr not_active Withdrawn
- 2000-10-11 AT AT00968928T patent/ATE314078T1/de not_active IP Right Cessation
- 2000-10-11 EP EP00968928A patent/EP1246627B1/fr not_active Expired - Lifetime
- 2000-10-11 WO PCT/US2000/027962 patent/WO2001028492A2/fr active IP Right Grant
- 2000-10-11 AU AU78771/00A patent/AU7877100A/en not_active Abandoned
- 2000-10-11 CA CA002387558A patent/CA2387558A1/fr not_active Abandoned
- 2000-10-11 JP JP2001531088A patent/JP2003511550A/ja active Pending
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Also Published As
Publication number | Publication date |
---|---|
EP1246627A2 (fr) | 2002-10-09 |
MXPA02003890A (es) | 2002-12-13 |
DE60025272D1 (de) | 2006-02-02 |
CA2387558A1 (fr) | 2001-04-26 |
WO2001028492A2 (fr) | 2001-04-26 |
US20030035787A1 (en) | 2003-02-20 |
ATE314078T1 (de) | 2006-01-15 |
AU7877100A (en) | 2001-04-30 |
EP1464673A2 (fr) | 2004-10-06 |
WO2001028492A3 (fr) | 2001-09-13 |
EP1246627B1 (fr) | 2005-12-28 |
EP1246627A4 (fr) | 2003-04-02 |
JP2003511550A (ja) | 2003-03-25 |
US6468519B1 (en) | 2002-10-22 |
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