Classifications

• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
  • A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
  • A61F5/0003—Apparatus for the treatment of obesity; Anti-eating devices
  • A61F5/0089—Instruments for placement or removal
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
  • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
  • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
  • A61B17/22031—Gripping instruments, e.g. forceps, for removing or smashing calculi
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
  • A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
  • A61F5/0003—Apparatus for the treatment of obesity; Anti-eating devices
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
  • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
  • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
  • A61B17/221—Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
  • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
  • A61B17/34—Trocars; Puncturing needles
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
  • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
  • A61B17/34—Trocars; Puncturing needles
  • A61B17/3417—Details of tips or shafts, e.g. grooves, expandable, bendable; Multiple coaxial sliding cannulas, e.g. for dilating
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
  • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
  • A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
  • A61B2017/00238—Type of minimally invasive operation
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
  • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
  • A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
  • A61B2017/00287—Bags for minimally invasive surgery
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
  • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
  • A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
  • A61B2017/00349—Needle-like instruments having hook or barb-like gripping means, e.g. for grasping suture or tissue
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
  • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
  • A61B17/34—Trocars; Puncturing needles
  • A61B2017/348—Means for supporting the trocar against the body or retaining the trocar inside the body
  • A61B2017/3482—Means for supporting the trocar against the body or retaining the trocar inside the body inside
  • A61B2017/3484—Anchoring means, e.g. spreading-out umbrella-like structure
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
  • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
  • A61B17/34—Trocars; Puncturing needles
  • A61B2017/348—Means for supporting the trocar against the body or retaining the trocar inside the body
  • A61B2017/3482—Means for supporting the trocar against the body or retaining the trocar inside the body inside
  • A61B2017/3484—Anchoring means, e.g. spreading-out umbrella-like structure
  • A61B2017/3488—Fixation to inner organ or inner body tissue
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
  • A61B2217/00—General characteristics of surgical instruments
  • A61B2217/002—Auxiliary appliance
  • A61B2217/005—Auxiliary appliance with suction drainage system

Definitions

• the present invention relates to the technical field of medical devices intended to be introduced into the working channel of an endoscope or any other equivalent device for carrying out various manipulations within the interior of the organs or cavities of the body of a patient.
• the present invention relates to an endoscopic medical device for recovery, in particular of any foreign body related to a flexible and perforable pocket located in the stomach.
• Such recovery devices are also called explantation devices.
• intragastric devices of the balloon type the installation of which is relatively easy, since it can be carried out by gastroenterologists or surgeons, by natural route and under endoscopic control, under local or general anesthesia.
• Such intragastric balloons placed in the stomach of an obese person, decrease the useful volume of the stomach, which has the effect of giving the obese person a feeling of satiety while absorbing quantities of less than what is necessary to obtain the same feeling of satiety without this intragastric balloon. Consequently, the establishment of an intragastric balloon has the effect of reducing the appetite of the obese person, and thus induces in him a significant loss of weight.
• intragastric balloons are formed by a pocket made of a flexible and expandable material, and are inserted empty endoscopically into the stomach. They are then filled with a fluid (gas or liquid) sterile or not. When full, the balloon is therefore too large to pass into the intestine; it therefore floats freely in the stomach.
• the practitioner introduces into the stomach endoscopically a hollow catheter into which a thread guide is inserted, - the practitioner pierces the balloon with the catheter provided with his thread guide, - the wire guide is removed from the catheter to free a passage for the fluid,
• the catheter fitted with the lasso and the deflated balloon is extracted from the patient's stomach and body.
• This process has the drawback of being long, in particular because it uses two different tools (a first piercing and suction catheter and a second catheter fitted with a lasso).
• the operating time is thus lengthened, which obviously goes against the interest of the patient.
• Document EP-0 205 228 describes an endoscopic device provided on the one hand with a retractable needle making it possible to puncture an intragastric balloon filled with gas and on the other hand with a lasso or a gripping jaw in order to grasp the balloon for explanting.
• This device is however not suitable for balloons containing liquid, since it is not provided with a means for discharging the fluid to the outside of the patient's body. It is obviously unthinkable to completely empty a balloon filled with liquid directly in the patient's stomach, if only because a bacterial proliferation could have occurred in this liquid.
• the object assigned to the invention is therefore aimed at proposing a new medical device for explanting a flexible pouch making it possible to remedy the various drawbacks listed above and capable of allowing a rapid, safe, inexpensive explantation operation, and facilitating the practitioner's work.
• Another object of the invention aims to propose a new atraumatic explantation device operating in a simple and reliable manner.
• Another object of the invention is to propose a new medical device for explanting a flexible bag capable of ensuring the lasso function, well known to practitioners.
• Another object of the invention is to propose a new explantation device which is particularly easy and inexpensive to manufacture.
• Another object of the invention is to propose a new explantation device for single or multiple use.
• a medical device for explanting a flexible bag whose interior contains a fluid, which bag comprises an envelope having an internal face, said device comprising at least one perforation means and means for mooring the pocket for explanting, characterized in that said perforation means makes it possible to make an opening in the flexible pocket to allow the passage of the mooring means, which is formed by a anchoring means acting from the inside of the pocket on a portion of said inner face of the envelope, to generate sufficient support for explantation.
• FIG. 1 illustrates, in a schematic perspective view, an embodiment of an explantation device according to the invention in the deactivated position, that is to say when the anchoring means is not able to generate support on the internal face of the envelope.
• FIG. 2 illustrates, in a schematic perspective view, the device shown in Figure 1 in the anchoring position, that is to say when the anchoring means is activated and is capable of generating a support on the internal face of the envelope.
• FIG. 3 illustrates, in a partial view in longitudinal section, a detail of the device shown in FIGS. 1 and 2.
• Figure 4 illustrates, in a sectional view, a detail of the device shown in Figures 1 to 3.
• FIG. 5 illustrates, in a schematic sectional view, a detail of embodiment of a variant of a medical device for explanting a flexible bag according to the invention.
• FIG. 6 illustrates, in a schematic perspective view, a detail of an alternative embodiment of a medical explantation device according to the invention.
• FIG. 7 illustrates, in a schematic perspective view, a detail of an alternative embodiment of a medical explantation device according to the invention.
• FIGS 1, 2, 6 and 7 illustrate an exemplary embodiment of a medical explantation device 1 of a flexible bag P whose interior contains a fluid, which bag P comprises an envelope E having an internal face F.
• the device comprises at least one perforation means 2C and a means for securing the pocket, in order to explant it.
• the perforation means 2C makes it possible to make an orifice in the flexible pocket to allow the passage of the mooring means, which is formed by an anchoring means 12 acting from the inside of the pocket on a portion of the inner face of the envelope, to generate sufficient support for explanting the pocket.
• the anchoring means 12 is able to deploy, its deployment being controlled by a control member 6 (not shown in Figures 6 and 7).
• the deployment of the anchoring means 12 consists for the latter of passing from a state which can be described as deactivated, where it occupies a reduced bulk, as shown in FIG. 1, to an activated state, such that this is shown in FIGS. 2, 4, 6 and 7, where the anchoring means 12 occupies a larger size, in order to be able to come to bear on a portion of the internal face F of the envelope E of the pocket P, so as to cause the latter when the medical explantation device 1 is subjected to a movement of withdrawal from the patient's body.
• Such a result can for example be obtained with an anchoring means 12 in the deployed state capable of presenting a bearing surface with the inner face F of the envelope E large enough to allow the explantation of the pocket. It is of course conceivable to arrive at a similar result with a smaller support surface, which could for example consist only of support points, as is obtained with the example of device 1 shown in the figure. 7, these support points being however judiciously distributed so as to transmit the explantation movement to the pocket, without risk for the pocket to be damaged to the point of escaping from the anchoring means 12.
• the medical explantation device 1 of a flexible bag P according to the invention comprises a means 3, 8 for evacuating the fluid contained inside the bag towards the outside of the patient's body.
• the medical explantation device 1 according to the invention can thus, in a preferential manner, make it possible to aspirate the fluid contained inside the pocket while the latter is still contained inside the patient's body.
• the anchoring means 12 is formed by a structure forming an articulated trellis comprising at least one anchoring arm 12D, said structure having a front termination 20 and a rear termination 21, the approximation controlled by the control member (not shown) causes the deployment of at least one anchoring arm 12D.
• the anchoring arm 12D can advantageously be composed of two elongated pieces in the form of a beam 30, 31, these beams each having two ends respectively 30A, 30B, 31 A, 31 B. Each of these beams has one of its ends 30A, 31 A linked to pivoting with respectively the front termination 20 and the rear termination 21, the other two ends 30B, 31 B of the beams being linked together to pivot.
• the front 20 and rear 21 terminations are slidably mounted, so that, when they are at a maximum from each other, the beams 30, 31 are aligned, and when we approach said terminations 20, 21, the beams 30, 31 will move in a pivoting manner, so forming an anchoring arm 12D transversely to the axis of the sliding movement of the front and rear terminations 20, 21.
• an explantation device 1 comprises, as shown in FIGS. 1 and 2, a hollow tube 2 having a distal part 2A comprising the perforation means 2C and a proximal part 2B, said distal 2A and proximal 2B parts delimiting between them an internal volume 3.
• This hollow tube 2 is preferably made of a material having a good flexibility / rigidity compromise, so that it can be used as a hollow catheter and as such be introduced into an endoscope (or any other similar device) provided with an operating channel with a diameter preferably greater than 2.8 mm. It is obvious that this latter value is not limiting, and that the explantation device according to the invention can be used with an operating channel of any diameter.
• the perforation means 2C can advantageously be, as shown in FIGS. 1, 2 and 4, formed by the tip of an insert and threaded at the level of the distal part 2A of the hollow tube 2, so as to form a regular extension of the distal part 2A.
• the perforation means such as for example bevelling the distal part 2A or the placement of a needle, without departing from the scope of the invention.
• the medical explantation device in accordance with the above preferred embodiment variant of the invention also comprises a wire guide 4 disposed in the internal volume 3 of the hollow tube 2 and having a front end 4A and a rear end 4B.
• wire guide designates a cable of any section, having a good compromise between rigidity and flexibility, so as to stiffen the hollow tube 2, in particular with a view to a perforation to be made at the end 2A, while being sufficiently flexible to be able to form a lasso loop.
• the medical explantation device 1 also comprises an external connector 5, mounted at the level of the proximal part 2B by means of a sleeve 7 having a cavity 7A, and comprising the control member 6 arranged so as to allow a user to exert at least tensile and compressive forces on the wire guide 4.
• said control member 6 is mounted movable relative to the sleeve 7 , the cavity 7A of the latter communicating with the outside by means of one or more tubular ends 8.
• the front 4A and rear 4B ends of the wire guide 4 are secured respectively to the distal part 2A of the hollow tube 2 and to the member 6.
• the hollow tube 2 comprises at least one weakening segment 8 extending between a front section 9 and a rear section 10 of the hollow tube 2, long enough to define with said sections 9, 10 a portion 11 of hollow tube 2 which is subject, when the user exerts traction on the rear end 4B via the control member 6 thereby causing axial compression of the hollow tube 2, to a mechanical buckling causing its deformation towards the outside of the internal volume 3 along said at least one weakening segment 8, so that said portion 11 forms the anchoring means able to deploy 12.
• the buckling (or buckling) of a part is a well-known mechanical instability phenomenon which results in the deformation (which can simply be a curvature) of the part under the effect of a longitudinal compressive force which it undergoes at its extremities.
• the buckling phenomenon generally only occurs for parts such as plates or beams, at least one of the dimensions of which is much less than the other two dimensions (for example, for a plate, the thickness of which is very less than length and width).
• the embrittlement segment (s) 8 with which the hollow tube 2 of the medical explantation device 1 is provided in accordance with the preferred variant of the invention, has (have) the object of delimiting a portion of the hollow tube 11 corresponding under buckling conditions, that is to say being composed of one or more elements whose length is much greater than at least the thickness (and possibly the width).
• the portion of hollow tube 11 consists of a plurality of sections in the form of a beam which, under the effect of the axial compression, will bend sharply to form several arms 12D anchor, without of course breaking.
• the explantation device according to the invention can be for single or multiple use and can, as such, be sterilized as many times as necessary.
• the deflection zones 12A, 12B, 12C of the sections that is to say mainly the ends and the central zone
• the weakening segment (s) 8 extends (s) rectilinearly between the front section 9 and the rear section 10.
• the weakening segment (s) 8 extends (s) parallel to the axis of symmetry of the hollow tube 2 between the front section 9 and the rear section 10, as shown in FIGS. Figures 1, 2 and 4.
• embrittlement segment (s) 8 it is however possible, without departing from the scope of the invention, for the embrittlement segment (s) 8 to extend according to other shapes, for example according to a wavy or zigzag curve between the front section 9 and the rear section 10.
• the weakening segments 8 are at least two in number, and are distributed angularly in a regular manner.
• the embrittlement segments 8 are three in number, distributed regularly around the circumference of the hollow tube.
• the weakening segments 8 are identical in nature.
• the weakening segment (s) 8 is (are) formed by one (or more) slot (s), as shown in FIGS. 1, 2 and 4. It is understood in this case that the manufacture of the embrittlement segment 8 is extremely easy and inexpensive, since it consists in simply preferring the hollow tube 2.
• weakening segment (s) 8 it is possible, without departing from the scope of the invention, for the weakening segment (s) 8 to be formed by means other than slots.
• weakening segments 8 constituted by a series of successive perforations forming one (or more) line (s) of dotted material capable of tearing under the effect of mechanical buckling.
• the deformation of the portion 1 1 of hollow tube 2 comprises at least one bending substantially at the level of the middle zone 12A of said portion 11.
• each of these sections folds in its middle, as shown in Figures 2 and 4.
• the anchoring means constituted by one or more folded section (s) does not have sharp edges, asperities or the like, which gives it an atraumatic character for the walls of the stomach.
• the perforation means 2C can be deactivated.
• This deactivation can be made possible for example by the means presented in FIG. 5, where the distal part 2A is shaped like a cone having a point 2C, which is made integral with the front end 4A of the wire guide 4, for example by bonding.
• the distal part 2A is made of a more flexible and ductile material than that constituting the rest of the hollow tube 2, in order to be able to retract in the internal volume 3 when a traction is exerted on the end 4B of the wire guide 4.
• the thread guide 4 is in turn provided with a cam 13 having a inclined sliding plane 13A and a bearing surface 13B, said cam being shaped so as to cooperate with a stop system 14 integral with the hollow tube 2, as follows: when traction is exerted on the wire guide 4 , it will move by driving the tip 2C, as authorized by the flexibility of the material constituting the distal part 2A, towards the proximal part 2B, thus causing contact between the inclined plane 13A and the stop 14.
• the latter is provided with opening means 14A having a hinge function, so that under the effect of the thrust exerted by the inclined plane 13A, the stop 14 opens to leave the cam 13, but only once the inclined plane 13A passed, it returns in an elastic locking position, so as to come to bear on the surface 13B.
• the perforation means is thus deactivated, since the tip 2C has returned to the internal volume 3 and no longer projects from the hollow tube 2, the deactivation position being locked by the cam / stop system 13, 14, with which the tube is provided. hollow 2 and the wire
• the external connector 5 is tightly secured to the proximal part 2B, so that the cavity 7A and the internal volume 3 form a single volume, the wire guide 4 occupying a sufficiently reduced space in said volume.
• This sealed connection can for example be carried out, as shown in FIG. FIG. 3, by force insertion of the sleeve 7 into the proximal part 2B, said sleeve comprising a connection zone 7B advantageously provided with means forming serrations 7C, cooperating with complementary forms 7D with which the proximal part 2B is provided, so as to ensure secure and watertight attachment.
• the seal between the sleeve 7 and the control member 6 can advantageously be produced by an O-ring seal 6A, as illustrated in FIG. 3.
• control member 6 is slidably mounted axially in the cavity 7A of the sleeve 7, so that the sliding of the control member 6 controls the traction / compression of the wire guide 4.
• control member 6 is mounted in the cavity 7A of the sleeve by means of a helical translation link, the axis of which is parallel to the axis of the hollow tube 2, so that than the movement (by screwing / unscrewing) of the control member 6 controls the compression traction of the wire guide 4.
• the medical explantation device 1 is arranged so that a portion of the wire guide 4 is suitable, when the wire guide 4 is subjected to a compression force induced by an action of the user on the control member 6, to exit out of the internal volume 3, so as to deploy to form a lasso loop 4C, the perimeter of which is adjustable by action of the user on the control member 6.
• the explantation device 1 thus retains the lasso function well known to practitioners, which may prove useful if it is impossible to anchor from inside the balloon, if the latter is in a degraded state for example.
• the lasso as obtained with the explantation device 1 in accordance with the invention has particularly advantageous handling and grip qualities, in particular because the loop 4C of the lasso "rests" on a rigid structure, constituted by the hollow tube 2.
• the medical device for explanting a flexible bag according to the invention is particularly well suited to the recovery in the stomach by endoscopic route of intragastric balloons intended for the treatment of obesity.
• the operation of the explantation device 1 according to the invention is as follows.
• the explantation device 1 is introduced into the operating channel of an endoscope immersed in the digestive tract of a patient.
• the endoscope provided with an operating channel with a diameter preferably at least equal to 2.8 mm, allows at the same time to view and approach directly in stomach the intragastric balloon to be extracted.
• This balloon may or may not be filled with a liquid or gaseous substance.
• the practitioner performing the explanting operation by acting on the mobility of the hollow tube 2 in the operating channel of the endoscope, perforates the intragastric balloon using the deactivatable perforation means 2C, and introduces the distal part 2A of the hollow tube 2 at least up to section 10 in the interior of the balloon.
• the practitioner then acts on the control member 6 so as to exert a tensile force on the wire guide 4.
• the tube hollow 2 is compressed axially, which has the effect, at the weakening segments 8, of deploying by buckling the anchoring means 12, advantageously formed by a single or multi-arm anchoring frame.
• This operation also has the effect, for a device of the type shown in FIG. 5, of deactivating the perforation means 2C.
• the intragastric balloon is thus stabilized in position by the anchoring frame.
• the practitioner can at this time empty the balloon, by connecting the explantation device 1 to a suction system by means of the end piece 8 of the external connector 5.
• the practitioner then pulls on the hollow tube 2 so as to block the envelope E of the balloon supported between the anchoring frame and the edge of the distal orifice of the endoscope.
• the practitioner can then extract the balloon by exerting a continuous pull on the wire guide 4 via the control member 6, so as to keep deployed the anchoring means 12, while raising the endoscope out of the patient's body.
• the explantation operation is thus carried out with a single atraumatic tool integrating the functions of perforation of the intragastric balloon, suction of the content of the intragastric balloon, and internal anchoring of said balloon.
• the explanting device also makes it possible to deploy a lasso loop 4C in the following manner: it suffices to push back the wire guide 4 by means of the control member 6 until forming a loop 4C through one of the openings in the hollow tube 2 following the deployment of the anchoring means 12.
• the lasso thus formed also has an atraumatic character for the walls of the stomach.
• the practitioner can then proceed to take an intragastric balloon using the lasso, which is a tool which he commonly uses.
• the fact that the lasso rests on a more rigid structure (formed by the hollow tube 2) than the usual structures of this type of instrument allows greater grip efficiency for simplified handling.
• the perforating means 2C being deactivated, there is no risk of injuring the patient during the operation.
• the explantation device according to the invention provides the practitioner with greater simplicity, safety and operating efficiency, while reducing the gestures to be performed.
• the invention finds its industrial application in the design, manufacture and use of explantation devices in the medical field.

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• Health & Medical Sciences (AREA)
• Life Sciences & Earth Sciences (AREA)
• Animal Behavior & Ethology (AREA)
• General Health & Medical Sciences (AREA)
• Orthopedic Medicine & Surgery (AREA)
• Engineering & Computer Science (AREA)
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• Heart & Thoracic Surgery (AREA)
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• Nursing (AREA)
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• Media Introduction/Drainage Providing Device (AREA)

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• 2001
  • 2001-12-28 FR FR0117099A patent/FR2834198B1/fr not_active Expired - Fee Related
• 2002
  • 2002-12-23 AU AU2002364482A patent/AU2002364482A1/en not_active Abandoned
  • 2002-12-23 WO PCT/FR2002/004537 patent/WO2003055419A1/fr not_active Application Discontinuation
  • 2002-12-23 EP EP02799846A patent/EP1458315A1/de not_active Withdrawn
  • 2002-12-23 US US10/500,242 patent/US20050070951A1/en not_active Abandoned

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