Classifications

• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
  • A61Q19/00—Preparations for care of the skin
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K8/00—Cosmetics or similar toiletry preparations
  • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
  • A61K8/04—Dispersions; Emulsions
  • A61K8/046—Aerosols; Foams
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K8/00—Cosmetics or similar toiletry preparations
  • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
  • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
  • A61K8/25—Silicon; Compounds thereof
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K8/00—Cosmetics or similar toiletry preparations
  • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
  • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
  • A61K8/26—Aluminium; Compounds thereof
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K8/00—Cosmetics or similar toiletry preparations
  • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
  • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
  • A61K8/73—Polysaccharides
  • A61K8/731—Cellulose; Quaternized cellulose derivatives
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K8/00—Cosmetics or similar toiletry preparations
  • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
  • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
  • A61K8/73—Polysaccharides
  • A61K8/732—Starch; Amylose; Amylopectin; Derivatives thereof
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K8/00—Cosmetics or similar toiletry preparations
  • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
  • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
  • A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
  • A61K8/8105—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers
  • A61K8/8111—Homopolymers or copolymers of aliphatic olefines, e.g. polyethylene, polyisobutene; Compositions of derivatives of such polymers
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K8/00—Cosmetics or similar toiletry preparations
  • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
  • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
  • A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
  • A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
  • A61K8/8147—Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K8/00—Cosmetics or similar toiletry preparations
  • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
  • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
  • A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
  • A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
  • A61K8/8152—Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K8/00—Cosmetics or similar toiletry preparations
  • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
  • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
  • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
  • A61K8/87—Polyurethanes
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
  • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
  • A61Q1/02—Preparations containing skin colorants, e.g. pigments
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
  • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
  • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations

Definitions

• the present invention relates to self-foaming and / or foam-like cosmetic and dermatological preparations, in particular skin-care cosmetic and dermatological preparations.
• Foams or foam-like preparations belong to the disperse systems.
• Emulsions are two- or multi-phase systems of two or more liquids which are insoluble or only slightly soluble in one another.
• the liquids pure or as solutions
• the liquids are present in an emulsion in a more or less fine distribution, which is generally only of limited stability.
• Foams are structures made of gas-filled, spherical or polyhedral cells, which are delimited by liquid, semi-liquid, highly viscous or solid cell bridges.
• the cell bridges connected via so-called nodes, form a coherent framework.
• the foam lamellae (closed-cell foam) stretch between the cell bars. If the foam lamellae are destroyed or flow back into the cell webs at the end of the foam formation, an open-cell foam is obtained.
• Foams are also thermodynamically unstable, since surface energy can be obtained by reducing the surface. The stability and therefore the existence of a foam depends on the extent to which it can prevent its self-destruction.
• Cosmetic foams are generally dispersed systems composed of liquids and gases, the liquid being the dispersant and the gas being the dispersed substance. Foams made from low-viscosity liquids are temporarily stabilized by surface-active substances (surfactants, foam stabilizers). Because of their large inner surface, such surfactant foams have a strong adsorption capacity, which is used, for example, in cleaning and washing processes. Accordingly, cosmetic foams are used in particular in the areas of cleaning, for example as shaving cream, and hair care.
• surfactants foam stabilizers
• foam gas is blown into suitable liquids, or foam formation is achieved by vigorous beating, shaking, spraying or stirring the liquid in the gas atmosphere in question, provided that the liquids contain suitable surfactants or other surface-active substances (so-called foaming agents) that besides interfacial activity also possess a certain film-forming ability.
• suitable surfactants or other surface-active substances so-called foaming agents
• Cosmetic foams have the advantage over other cosmetic preparations in that they allow a fine distribution of active ingredients on the skin.
• cosmetic foams can generally only be achieved by using special surfactants, which moreover are often not very kind to the skin.
• Post-foaming cosmetic preparations are also known per se. They are first applied to the skin in a fluid form from an aerosol container and After a short delay, develop the actual foam there, for example a shaving foam, under the influence of the post-foaming agent contained. Post-foaming preparations are often in special embodiments such as post-foaming shaving gels or the like.
• German Offenlegungsschrift DE 197 54 659 discloses that carbon dioxide is a suitable active ingredient for stabilizing or increasing the epidermal ceramide synthesis rate, which can serve to strengthen the permeability barrier, reduce the trans-epidermal water loss and increase the relative skin moisture.
• the CO 2 is dissolved in water, for example, with which the skin is then rinsed.
• the prior art has hitherto known no cosmetic or dermatological foundations into which a gaseous active ingredient could be incorporated in a sufficient, ie effective, concentration.
• Another object of the present invention was therefore to find cosmetic or dermatological bases in which effective amounts of gaseous active ingredients can be incorporated.
• At least one emulsifier A selected from the group of fully, partially or non-neutralized, branched and / or unbranched, saturated and / or unsaturated fatty acids with a chain length of 10 to 40 carbon atoms,
• At least one emulsifier B selected from the group of polyethoxylated fatty acid esters with a chain length of 10 to 40 carbon atoms and with a degree of ethoxylation of 5 to 100 and
• At least one co-emulsifier C selected from the group consisting of saturated and / or unsaturated, branched and / or unbranched fatty alcohols with a chain length of 10 to 40 carbon atoms, II. Up to 30% by weight, based on the total weight of the Preparation - a lipid phase, III. 1 to 90% by volume, based on the total volume of the preparation, of at least one gas selected from the group consisting of air, oxygen, nitrogen, helium, argon,
• Nitrous oxide (N 2 O) and carbon dioxide (CO 2 ) IV 0.01 to 10% by weight of one or more gel formers selected from the group of inorganic thickeners,
• V one or more substances selected from the group of organic hydrocolloids and
• foam-like cosmetic emulsions which are distinguished by a high gas input cannot be formulated or produced industrially without propellant gas.
• systems based on classic emulsifiers and gel formers and developing a foam with high stability by shear could only be produced with the aid of post-foaming agents according to the prior art.
• the invention supports the entry of gases and achieves a stabilizing and clearly after-foaming effect over a longer storage period even at higher temperatures (eg 40 ° C.). It was particularly surprising that common post-foaming agents such. B. propellant gases can be dispensed with.
• the entry of Gases are surprisingly extremely increased compared to the prior art. For example, foam reinforcement with up to 100% increased gas volume can be achieved without using conventional foaming agents such as surfactants according to the prior art.
• self-foaming or “foam-like” is to be understood to mean that the gas bubbles (as desired) are present in one (or more) liquid phase (s), the formulations not necessarily having the appearance of a foam macroscopically
• Self-foaming and / or foam-like cosmetic or dermatological preparations according to the invention can, for. B. represent macroscopically visible dispersed systems from gases dispersed in liquids.
• the foam character can, for example, only become visible under a (light) microscope.
• self-foaming and / or foam-like preparations according to the invention especially when the gas bubbles are too small to be recognized under a light microscope - can also be recognized from the large increase in volume of the system.
• the preparations according to the invention are extremely satisfactory preparations in every respect. It was particularly surprising that the foam-like preparations according to the invention are extremely stable - even with an unusually high gas volume. Accordingly, they are particularly suitable to serve as the basis for forms of preparation with a variety of uses.
• the preparations according to the invention show very good sensory properties, such as, for example, the spreadability on the skin or the ability to be drawn into the skin, and are furthermore distinguished by an above-average skin care.
• the subject of the invention is furthermore the use of self-foaming and / or foam-like cosmetic or dermatological preparations, which I. an emulsifier system, which from
• At least one emulsifier A selected from the group of fully, partially or not neutralized, branched and / or unbranched, saturated and / or unsaturated fatty acids with a chain length of 10 to 40 carbon atoms,
• At least one emulsifier B selected from the group of polyethoxylated fatty acid esters with a chain length of 10 to 40 carbon atoms and with a degree of ethoxylation of 5 to 100 and
• At least one co-emulsifier C selected from the group consisting of saturated and / or unsaturated, branched and / or unbranched fatty alcohols with a chain length of 10 to 40 carbon atoms, and II. Up to 30% by weight of a lipid phase, based on the Total weight of the preparation
• V one or more substances selected from the group of organic hydrocolloids and
• the emulsifier (s) A are preferably selected from the group of fatty acids which are wholly or partly neutralized with customary alkalis (such as sodium and / or potassium hydroxide, sodium and / or potassium carbonate and mono- and / or triethanolamine) ,
• customary alkalis such as sodium and / or potassium hydroxide, sodium and / or potassium carbonate and mono- and / or triethanolamine
• stearic acid and stearates isostearic acid and isostearates, palmitic acid and palmitates, and myristic acid and myristates are particularly advantageous.
• the emulsifier (s) B are preferably selected from the following group: PEG-9 stearate, PEG-8 distearate, PEG-20 stearate, PEG-8 stearate, PEG-8 oleate, PEG-25 glyceryl trioleate, PEG-40 sorbitan lanolate, PEG-15 glyceryl ricinoleate, PEG-20 glyceryl stearate, PEG-20 glyceryl isostearate, PEG-20 glyceryl oleate, PEG-20 stearate, PEG-20 methylglucose sesquistearate 30-glyceryl isostearate, PEG-20 glyceryl laurate, PEG-30 stearate, PEG-30 glyceryl stearate, PEG-40 stearate, PEG-30 glyceryl laurate, PEG-50 stearate, PEG-1 OO stearate, PEG-150 laurate.
• the co-emulsifier (s) C are preferably selected from the following group: butyl octanol, butyl decanol, hexyl octanol, hexyl decanol, octyl decanol, behenyl alcohol (C 22 H 45 OH), cetearyl alcohol [a mixture of cetyl alcohol (C 6 H 33 OH) and stearyl alcohol (C 18 H 3 OH)], lanolin alcohols (wool wax alcohols, which represent the unsaponifiable alcohol fraction of the wool wax which is obtained after the saponification of wool wax). Cetyl and cetylstearyl alcohol are particularly preferred.
• weight ratios of emulsifier A to emulsifier B to coemulsifier C (A: B: C) as a: b: c, where a, b and c independently of one another are rational numbers from 1 to 5, preferably from 1 can represent up to 3.
• a weight ratio of approximately 1: 1: 1 is particularly preferred.
• the total amount of emulsifiers A and B and of coemulsifier C is advantageous for the total amount of emulsifiers A and B and of coemulsifier C to be in the range from 2 to 20% by weight, advantageously from 5 to 15% by weight, in particular from 8 to 13% by weight. %, each based on the total weight of the formulation.
• the gas phase of the preparations contains carbon dioxide or consists entirely of carbon dioxide. It is particularly advantageous if carbon dioxide is one or the active ingredient in the preparations according to the invention.
• compositions according to the invention develop into fine-bubble foams already during their production - for example during stirring or during homogenization.
• fine-bubble, rich foams of excellent cosmetic elegance are available.
• the invention is special Preparations that are well tolerated by the skin are available, and valuable ingredients can be distributed particularly well on the skin.
• formulations according to the present invention contain further emulsifiers.
• Those emulsifiers which are suitable for producing W / O emulsions are preferably to be used, these being able to be present both individually and in any combination with one another.
• the other emulsifier (s) are advantageously selected from the group comprising the following compounds:
• the further emulsifier or emulsifiers are preferably selected from the group of the hydrophilic emulsifiers.
• Mono-, di-, trifatty acid esters of sorbitan are particularly preferred according to the invention.
• the total amount of the further emulsifiers is advantageously chosen to be less than 5% by weight, based on the total weight of the formulation.
• Particularly advantageous self-foaming and / or foam-like preparations in the sense of the present invention are free of mono- or diglyceryl fatty acid esters.
• Preparations according to the invention which contain no glyceryl stearate, glyceryl isostearate, glyceryl diisostearate, glyceryl oleate, glyceryl palmitate, glyceryl myristate, glyceryl alcoholate and / or glyceryl laurate are particularly preferred.
• the oil phase of the preparations according to the invention is advantageously selected from the group of nonpolar lipids with a polarity> 30 mN / m.
• Particularly advantageous nonpolar lipids for the purposes of the present invention are those listed below.
• hydrocarbons paraffin oil and other hydrogenated polyolefins such as hydrogenated polyisobutenes, squalane and squalene are particularly advantageous for the purposes of the present invention.
• the content of the lipid phase is advantageously chosen to be less than 30% by weight, preferably between 2.5 and 30% by weight, particularly preferably between 5 and 15% by weight, in each case based on the total weight of the preparation. It may also be advantageous adherent, although not mandatory, if the lipid phase contains up to 40% by weight - based on the total weight of the lipid phase - of polar lipids (with a polarity ⁇ 20 mN / m) and / or medium-polar lipids (with a polarity of 20 to 30 mN / m) contains.
• Particularly advantageous polar lipids for the purposes of the present invention are all native lipids, such as, for. B. olive oil, sunflower oil, soybean oil, peanut oil, rapeseed oil, almond oil, palm oil, coconut oil, castor oil, wheat germ oil, grape seed oil, safflower oil, evening primrose oil, macadamia nut oil, corn oil, avocado oil and the like and those listed below.
• native lipids such as, for. B. olive oil, sunflower oil, soybean oil, peanut oil, rapeseed oil, almond oil, palm oil, coconut oil, castor oil, wheat germ oil, grape seed oil, safflower oil, evening primrose oil, macadamia nut oil, corn oil, avocado oil and the like and those listed below.
• medium-polar lipids for the purposes of the present invention are those listed below.
• the inorganic thickener (s) can, for example, advantageously be selected from the group of modified or unmodified, naturally occurring or synthetic layered silicates. Although it is entirely favorable to use pure components, the preparations according to the invention can also advantageously contain mixtures of different modified and / or unmodified layered silicates.
• Layered silicates which are also called phyllosilicates, are to be understood in the context of this application as silicates and aluminosilicates in which the silicate or aluminate units are linked to one another via three Si-O or Al-O bonds and a corrugated sheet or layer structure form.
• the fourth Si-O or Al-O valence is saturated by cations.
• the layer structure is largely characterized by strong, covalent bonds.
• m is a number greater than zero and less than 2.
• the charge balance is preferably balanced by H + , alkali or alkaline earth metal ions.
• Aluminum as a counter ion is also known and advantageous. In contrast to the These compounds are called aluminosilicates aluminum silicates. "Aluminum aluminosilicates", in which aluminum is present both in the silicate network and as a counter ion, are also known and may be advantageous for the present invention.
• layered silicates are:
• Montmorillonite is the main mineral of the naturally occurring bentonites.
• Very advantageous inorganic gelling agents for the purposes of the present invention are aluminum silicates such as montmorillonites (bentonites, hectorites and their derivatives such as quaternium-18 bentonite, quaternium-18 hectorites, stearalkonium bentonites or stearalkonium hectorites) or magnesium-aluminum silicates (Veegum®- Types) and sodium-magnesium-silicates (Laponite® types)
• montmorillonites bentonites, hectorites and their derivatives such as quaternium-18 bentonite, quaternium-18 hectorites, stearalkonium bentonites or stearalkonium hectorites
• magnesium-aluminum silicates Veegum®- Types
• sodium-magnesium-silicates Liaponite® types
• Montmorillonites are clay minerals belonging to the dioctahedral smectites and are masses that swell in water but do not become plastic.
• the layer packs in the three-layer structure of montmorillonites can be reversibly incorporated by Water (in 2-7 times the amount) including substances such as As alcohols, glycols, pyridine, ⁇ -picoline, ammonium compounds, hydroxy-alumino-silicate ions etc. swell.
• Synthetic magnesium silicates or bentonites which are advantageous in the sense of the present invention are sold, for example, by Süd-Chemie under the trade name Optigel®.
• An aluminum silicate which is advantageous in the sense of the present invention is sold, for example, by R. T. Vanderbilt Comp., Inc., under the trade name Veegum®.
• the various Veegum @ types, all of which are advantageous according to the invention, are distinguished by the following compositions
• Bentone® is a trade name for various neutral and chemically inert gelling agents that are made up of long-chain, organic ammonium salts and special types of montmorillonite. Bentones swell in organic media and make them swell. The gels are stable in dilute acids and alkalis, but they lose some of their gelling properties if they are in contact with strong acids and alkalis for a long time. Due to their organophilic character, the bentones are difficult to wet with water.
• Bentone® types are sold, for example, by Kronos Titan: Bentone® 27, an organically modified montmorillonite, Bentone® 34 (dimethyldioctylammonium bentonite), which is produced according to US 2,531,427 and because of its lipophilic groups it is better in the lipophilic medium than swells in water, Bentone® 38, an organically modified montmorillonite, a cream-colored to white powder, Bentone® LT, a purified clay mineral, Bentone® Gel MIO, an organically modified montmorillonite, which is offered in fine suspension in mineral oil (SUS-71) ( 10% bentonite, 86.7% mineral oil and 3.3% wetting agent), Bentone® Gel IPM, an organically modified bentonite suspended in isopropyl myristate (10% bentonite, 86.7% isopropyl myristate, 3.3% wetting agent) ), Bentone® Gel CAO, an organically modified montmorillonite, which is absorbed in
• Bentone® Gel Lan II a bentonite paste in pure, liquid wool wax
• Bentone® Gel NV a 15% Bentone® 27 paste in dibutyl phthalate
• Bentone® Gel OMS a bentonite paste in Shellsol T.
• Bentone® Gel OMS 25 a bentonite paste in isoparaffinic hydrocarbons (Idopar® H), Bentone® Gel IPP, a bentonite paste in isopropyl palmitate.
• Bentone types can be used advantageously for the purposes of the present invention.
• Hydrocolloid is the technological short name for the more correct term “hydrophilic colloid”. Hydrocolloids are macromolecules that are largely linear in shape and have intermolecular interaction forces that enable side and main valence bonds between the individual molecules and thus the formation of a network-like structure.
• Such water-soluble polymers represent a large group of chemically very different natural and synthetic polymers, the common feature of which is their solubility in water or aqueous media. The prerequisite for this is that these polymers have a sufficient number of hydrophilic groups for water solubility and are not too strongly crosslinked.
• the hydrophilic groups can be nonionic, anionic or cationic in nature, for example as follows:
• the group of cosmetically and dermatologically relevant hydrocolloids can be divided as follows:.
• organic, natural compounds such as agar agar, carrageenan, tragacanth, gum arabic, alginates, pectins, polyoses, guar flour, locust bean gum, starch, dextrins, gelatin, casein,.
• organic, modified natural substances such as B. carboxymethyl cellulose and other cellulose ethers, hydroxyethyl and propyl cellulose and microcrystalline cellulose, the like, organic, fully synthetic compounds, such as.
• Microcrystalline cellulose is an advantageous hydrocolloid for the purposes of the present invention. It is available, for example, from the "FMC Corporation Food and Pharmaceutical Products” under the trade name Avicel®.
• a particularly advantageous product in the sense of the present invention is the type Avicel® RC-591, which is modified microcrystalline cellulose which is composed of 89% microcrystalline cellulose and 11% sodium carboxymethyl cellulose.
• Other commercial products in this raw material class are Avicel® RC7 CL, Avicel® CE-15, Avicel® 500.
• hydrocolloids which are advantageous according to the invention are, for example, methyl celluloses, as the methyl ethers of cellulose are referred to. They are characterized by the following structural formula
• R can represent a hydrogen or a methyl group.
• cellulose mixed ethers which are generally also referred to as methyl celluloses and which, in addition to a dominant content of methyl, additionally contain 2-hydroxyethyl, 2-hydroxypropyl or 2-hydroxybutyl groups.
• (Hydroxypropyl) methyl celluloses are particularly preferred, for example those sold under the trade name Methocel® E4M by Dow Chemical Comp. available.
• sodium carboxymethyl cellulose the sodium salt of the glycolic acid ether of cellulose, for which R in structural formula I can be a hydrogen and / or CH 2 COONa.
• R in structural formula I can be a hydrogen and / or CH 2 COONa.
• a preferred hydrocolloid for the purposes of the present invention is also xanthan (CAS No. 11138-66-2), also called xanthan gum, which is an anionic heteropolysaccharide which is generally formed from corn sugar by fermentation and is isolated as the potassium salt. It is produced by Xanthomonas campestris and some other species under aerobic conditions with a molecular weight of 2 * 10 6 to 24 * 10 6 .
• Xanthan is formed from a chain with ß-1, 4-bound glucose (cellulose) with side chains. The structure of the subgroups consists of glucose, mannose, glucuronic acid, acetate and pyruvate.
• Xanthan is the name for the first microbial anionic heteropolysaccharide.
• Xanthan is formed from a chain with ß-1, 4-bound glucose (cellulose) with side chains.
• the structure of the subgroups consists of glucose, mannose, glucuronic acid, acetate and pyruvate. The number of pyruvate units determines the viscosity of the xanthane.
• An advantageous hydrocollid in the sense of the present invention is also carrageenan, a gel-forming and similar to agar extract from North Atlantic red algae (Chondrus crispus and Gigartina stellata), which are counted as florids.
• carrageen is often used for the dried algae product and carrageenan for the extract from it.
• the carrageenan precipitated from the hot water extract of the algae is a colorless to sand-colored powder with a molecular weight range of 100,000-800,000 and a sulfate content of approx. 25%.
• Carrageenan which is very easily soluble in warm water; a thixotropic gel forms on cooling, even if the water content is 95-98%. The firmness of the gel is brought about by the double helix structure of the carrageenan.
• the gel-forming ⁇ fraction consists of D-galactose-4-sulfate and 3,6-anhydro- -D-galactose, which are alternately glycosidically linked in the 1,3 and 1,4 positions ( In contrast, agar contains 3,6-anhydro- ⁇ -L-galactose).
• the non-gelling ⁇ fraction is composed of 1,3-glycosidically linked D-galactose-2-sulfate and 1,4-linked D-galactose-2,6-disulfate residues and the like. in cold water easily soluble.
• the i-carrageenan composed of D-galactose-4-sulfate in 1,3-bond and 3,6-anhydro- ⁇ -D-galactose-2-sulfate in 1,4-bond is both water-soluble and gel-forming.
• Other types of carrageenan are also designated with Greek letters: ⁇ , ß, ⁇ , ⁇ , v, ⁇ , ⁇ , ⁇ , ⁇ .
• the type of cations present (K + , NH 4 + , Na + , Mg 2+ , Ca 2+ ) also influences the solubility of the carrageenans.
• Chitosan is also an advantageous hydrocollide for the purposes of the present invention.
• the use of chitosan in cosmetic preparations is known per se.
• Chitosan is a partially deacylated chitin. This biopolymer has u. a. film-forming properties and is characterized by a silky feeling on the skin.
• Chitosan is known to be used, for example, in hair care. It is better than the chitin on which it is based as a thickener or stabilizer and improves the adhesion and water resistance of polymer films. Representing a large number of prior art sites: H.P. Fiedler, "Lexicon of auxiliaries for pharmacy, cosmetics and related areas", third edition 1989, Editio Cantor, Aulendorf, p. 293, keyword "Chitosan”.
• n assumes values up to approx. 10,000
• X represents either the acetyl radical or hydrogen.
• Chitosan is formed by deacetylation and partial depolymerization (hydrolysis) of chitin, which is due to the structural formula is marked.
• Chitin is an essential component of the arthropod's ectoskeleton (e.g. insects, crabs, spiders) and is also found in supporting tissues of other organisms (e.g. molluscs, algae, fungi).
• chitosan In the range of approximately pH ⁇ 6, chitosan is positively charged and is also soluble there in aqueous systems. It is not compatible with anionic raw materials. Therefore, the use of nonionic emulsifiers is suitable for the production of chitosan-containing oil-in-water emulsions. These are known per se, for example from EP-A 776 657.
• Chitosans with a degree of deacetylation> 25%, in particular> 55 to 99% [determined by means of 1 H-NMR] are preferred according to the invention.
• chitosans with molecular weights between 10,000 and 1,000,000, in particular those with molecular weights between 100,000 and 1,000,000 [determined by means of gel permeation chromatography].
• Polyacrylates are also advantageous hydrocolloids to be used in the sense of the present invention.
• Polyacrylates which are advantageous according to the invention are acrylate-alkyl acrylate copolymers, in particular those which are selected from the group of the so-called carbomers or carbopols (Carbopol® is actually a registered trademark of the BF Goodrich Company).
• the acrylate-alkyl acrylate copolymers which are advantageous according to the invention are distinguished by the following structure:
• R ' represents a long-chain alkyl radical and x and y numbers which symbolize the respective stoichiometric proportion of the respective comonomers.
• acrylate copolymers and / or acrylate-alkyl acrylate copolymers which are available from the BFGoodrich Company under the trade names Carbopol® 1382, Carbopol® 981 and Carbopol® 5984, preferably polyacrylates from the group of the carbopols of types 980, 981, 1382, 2984, 5984 and particularly preferably Carbomer 2001
• alkyl acrylate to acrylate copolymers are also advantageous for the purposes of the present invention.
• the INCI name for such compounds is "Acrylates / C 10-30 Alkyl Acrylate Crosspolymer”.
• Particularly advantageous are those available under the trade names Pemulen TR1 and Pemulen TR2 from the BF Goodrich Company.
• ammonium acryloyldimethylt.auateyl / inylpyrrolidone copolymers have the empirical formula [C 7 H 16 N 2 SO] n [C 6 H 9 NO] m , corresponding to a statistical structure as follows
• copolymers / crosspolymers comprising acryloyldimethyl taurates such as Simugel® EG or Simugel® EG from Seppic S.A.
• Component (i) is, in particular, diols, amino alcohols, diamines, polyesterols, polyetherols with a number-average molecular weight of up to 3000 in each case or mixtures thereof, it being possible for up to 3 mol% of the compounds mentioned to be replaced by triols or triamines , Diols and polyester diols are preferred.
• component (i) comprises at least 50% by weight, based on the total weight of component (i), of a polyester diol.
• Suitable polyester diols are all those which are customarily used for the production of polyurethanes are, in particular reaction products of phthalic acid and diethylene glycol, isophthalic acid and 1, 4-butanediol, isophthalic acid / adipic acid and 1, 6-hexanediol and adipic acid and ethylene glycol or 5-NaSO 3 isophthalic acid, phthalic acid, adipic acid and 1, 6-hexanediol.
• Useful diols are e.g. B. ethylene glycol, propylene glycol, butylene glycol, neopentyl glycol, polyetherols, such as polyethylene glycols with molecular weights up to 3000, block copolymers of ethylene oxide and propylene oxide with number average molecular weights of up to 3000 or block copolymers of ethylene oxide, propylene oxide and butylene oxide, which are the alkylene oxide units included statistically distributed or polymerized in the form of blocks.
• Ethylene glycol, neopentyl glycol, di-, tri-, tetra-, penta or hexaethylene glycol are preferred.
• Useful diols are also poly ( ⁇ -hydroxycarbonic acid) diols.
• Suitable amino alcohols are e.g. B. 2-aminoethanol, 2- (N-methylamino) ethanol, 3-aminopropanol or 4-aminobutanol.
• Suitable diamines are e.g. B. ethylenediamine, propylenediamine, 1, 4-diaminobutane and 1,6-diaminohexane and ⁇ , ⁇ -diamines, which can be prepared by amination of polyalkylene oxides with ammonia.
• Component (ii) is in particular dimethylolpropanoic acid or compounds of the formulas
• RR stands for a C 2 -C 18 alkylene group and Me stands for Na or K.
• Component (iii) is in particular hexamethylene diisocyanate, isophorone diisocyanate, methyldiphenyl isocyanate (MDI) and / or tolylene diisocyanate.
• the polyurethanes are obtainable by reacting the compounds of groups (i) and (ii) with the compounds of group (iii) under an inert gas atmosphere in an inert solvent at temperatures from 70 to 130 ° C. This reaction can optionally be carried out in the presence of chain extenders in order to produce polyurethanes with higher molecular weights.
• the components [(i) + (ü)]: (iii) are advantageously used in a molar ratio of 0.8 to 1.1: 1.
• the acid number of the polyurethanes is determined by the composition and the concentration of the compounds of component (ii) in the mixture of components (i) + (ii).
• the H. Fikentscher K values (determined in 0.1% by weight solutions in N-methylpyrrolidone at 25 ° C. and pH 7) of 15 to 100, preferably 25 to 50.
• ⁇ r relative viscosity (dynamic viscosity of the solution / dynamic viscosity of the solvent)
• c mass concentration of polymer in the solution (in g / cm 3 ).
• Alkali metal bases such as sodium hydroxide solution, potassium hydroxide solution, sodium carbonate, sodium hydrogen carbonate, potassium carbonate or potassium hydrogen carbonate and alkaline earth metal bases such as calcium hydroxide, calcium oxide, magnesium hydroxide or magnesium carbonate as well as ammonia and amines can be used as the base for the neutralization of the polyurethanes.
• 2-Amino-2-methylpropanol, diethylaminopropylamine and triisopropanolamine have proven particularly useful for neutralizing the polyurethanes containing acid groups.
• the neutralization of the polyurethanes containing acid groups can also be carried out with the aid of mixtures of several bases, for.
• B. Mixtures of sodium hydroxide solution and triisopropanolamine. Depending on the application, the neutralization can be partially z. B. 20 to 40% or completely, ie 100%.
• Preferred diisocyanates are as indicated under 1 above.
• Compounds with two or more active hydrogen atoms are diols, amino alcohols, diamines, polyesterols. Polyamide diamines and polyetherols. Suitable compounds of this type are as indicated under 1 above.
• the polyurethanes are produced as described under 1 above.
• Charged cationic groups can be obtained from the present tertiary amino nitrogen atoms either by protonation, e.g. B. with carboxylic acids such as lactic acid, or by quaternization, z.
• B. with alkylating agents such as C to C 4 alkyl halides or sulfates in the polyureas. Examples of such alkylating agents are ethyl chloride, ethyl bromide, methyl chloride, methyl bromide, dimethyl sulfate and diethyl sulfate.
• RR ' represents a hydrogen atom or a C 1 -C 20 -alkyl group which is used in an amount which is sufficient for 0.35 to
• carboxyl groups contained in the polyurethane are at least partially neutralized with a suitable base.
• Carboxyl-containing polycondensation products from anhydrides of tri- or tetracarboxylic acids and diols, diamines or amino alcohols (polyesters, polyamides or
• Polyester These polymers and their preparation are described in more detail in DE-A-42 24 761, to which reference is hereby made in full. 5. Polyacrylates and polymethacrylates as described in more detail in DE-A-43 14 305, 36 27 970 and 29 17 504. Reference is hereby made in full to these publications.
• the polymers used according to the invention preferably have a K value of 25 to 100, preferably 25 to 50.
• the polymers in the composition according to the invention are generally present in an amount in the range from 0.2 to 20% by weight on the total weight of the agent.
• the salt is used in an amount effective to improve the interchangeability of the polymers. In general, the salt is used in an amount of 0.02 to 10% by weight, preferably 0.05 to 5% by weight and in particular 0.1 to 3% by weight, based on the total weight of the agent ,
• the hydrocolloids can furthermore advantageously be selected from the group of modified carbohydrate derivatives, starch and starch derivatives (distarch phosphate, sodium or aluminum starch octenyl succinate, wheat starch, corn starch (Amidon De Mais MST (Wackherr) , Argo Brand Maize Starch (Com Products), Pure-Dent (Grain Processing), Purity 21 C (National Starch), Rice Starch (DSA 7 (Agrana Starch), Oryzapeari (Ichimaru Pharcos), Hydroxypropyl Starch Phosphate Distarch Phosphate (Com PO4 (Agrana Starch ) Com PO4 (Tri-K)) Sodium maize starch octenyl succinate (C * EmCap - Instant 12639 (Cerestar USA)) Aluminum starch octenyl succinate (Covafluid AMD (Wackherr) Dry Flo-PC (National Starch) Dry Flo Pure (National
• the total amount of one or more hydrocolloids in the finished cosmetic or dermatological preparations is advantageously chosen to be less than 5% by weight, preferably between 0.1 and 1.0% by weight, based on the total weight of the preparations.
• the inorganic particulate hydrophobic and / or hydrophobized and / or oil-absorbing solid substances can, for example, advantageously be selected from the group of inorganic fillers (such as talc, kaolin, zeolites, boron nitride) • the inorganic pigments based on metal oxides and / or other metal compounds which are sparingly soluble or insoluble in water (in particular oxides of titanium, zinc, iron, manganese, aluminum, cerium)
• inorganic fillers such as talc, kaolin, zeolites, boron nitride
• the inorganic pigments based on silicon oxides (such as the types Aerosil-200, Aerosil 200 V in particular).
• silicate derivatives such as sodium silicoaluminate or fluoro magnesium silicate (submica types), calcium aluminum borosilicate.
• silica dimethyl silylate is preferred.
• microsphere particles which are based on crosslinked polymethyl methacrylates (INCI: crosslinked methyl methacrylates). These are marketed by SEPPIC under the trade names Micropeari® M305, Micropearl® 201, Micropearl® M 310 and Micropearl® MHB and are characterized by an oil absorption capacity of 40-100 g / 100g.
• Aerosils silicon dioxide obtained by thermal decomposition of ethyl silicate
• Aerosils are highly disperse silicas with an irregular shape, the specific surface area of which is usually very large (200 - 400 m 2 / g) and can be controlled depending on the manufacturing process.
• Aerosils to be used advantageously according to the invention are available, for example, under the trade names: Aerosil® 130 (Degussa Hüls) Aerosil® 200 (Degussa Hüls) Aerosil 255 (Degussa Hüls) Aerosil® 300 (Degussa Hüls) Aerosil® 380 (Degussa Hüls) B-6C ( Suzuki Yushi) CAB-O-SIL Fumed Silica (Cabot) CAB-O- SIL EH-5 (Cabot) CAB-O- SIL HS-5 (Cabot) CAB-O-SIL LM-130 (Cabot) CAB-O- SIL MS-55 (Cabot) CAB-O-SIL M-
• SiO 2 pigments in which the free OH groups on the particle surface have been (partially or completely) modified organically.
• silica silylates e.g. Aerosil R 812 (Degussa Hüls) CAB-O-SIL TS-530 (Cabot) Sipemat D 17 (Degussa Hüls) Wacker HDK H2000 (Wacker-Chemie)
• Polymethylsilsesquioxanes are available, for example, under the trade names Tospearl® 2000 B from GE Bayer Silicones, Tospearl 145A from Toshiba, AEC Silicone Resin Spheres from A & E Connock or Wacker - Belsil PMS MK from Wacker-Chemie.
• the cosmetic and / or dermatological preparations according to the invention can be composed as usual.
• Preparations for skin care are particularly advantageous for the purposes of the present invention: they can be used for cosmetic and / or dermatological light protection, for treating the skin and / or hair and as a make-up product in decorative cosmetics.
• Another advantageous embodiment of the present invention consists of after-sun products.
• cosmetic or topical dermatological compositions can be used for the purposes of the present invention, for example as a skin protection cream, day or night cream, etc. It may be possible and advantageous to use the compositions according to the invention as the basis for pharmaceutical formulations.
• the preparations according to the invention can also represent “cleaning foams” which, for example for removing make-up and / or make-up or as a mild wash foam - if necessary also for impure skin.
• cleaning foams can advantageously also be used as so-called “rinse off” preparations which are rinsed off the skin after use
• the cosmetic and / or dermatological preparations according to the invention can also advantageously be in the form of a foam for the care of the hair or the scalp, in particular a foam for inserting the hair, a foam which is used for blow-drying the hair, a hairdressing and treatment foam.
• the cosmetic and dermatological preparations according to the invention are applied to the skin and / or the hair in a sufficient amount in the manner customary for cosmetics.
• the cosmetic and dermatological preparations according to the invention can contain cosmetic auxiliaries as are usually used in such preparations, e.g. B. preservatives, preservation aids, bactericides, perfumes, dyes, pigments that have a coloring effect, moisturizing and / or moisturizing substances, fillers that improve the feeling on the skin, fats, oils, waxes or other conventional components of a cosmetic or dermatological formulation such as alcohols , Polyols, polymers, foam stabilizers, electrolytes, organic solvents or silicone derivatives.
• cosmetic auxiliaries e.g. B. preservatives, preservation aids, bactericides, perfumes, dyes, pigments that have a coloring effect, moisturizing and / or moisturizing substances, fillers that improve the feeling on the skin, fats, oils, waxes or other conventional components of a cosmetic or dermatological formulation such as alcohols , Polyols, polymers, foam stabilizers, electrolytes, organic solvents or silicone derivatives.
• Advantageous preservatives in the sense of the present invention are, for example, formaldehyde releasers (such as, for example, DMDM hydantoin), iodopropylbutylearbamates (for example those available from Lonza under the trade names Koncyl-L, Koncyl-S and Konkaben LMB) Parabens, phenoxyethanol, ethanol, benzoic acid and the like.
• the preservation system usually also advantageously comprises preservation aids, such as, for example, octoxyglycerol, glycine soya, etc.
• antioxidants are used as additives or active ingredients.
• the preparations advantageously contain one or more antioxidants.
• Antioxidants to be used can be all antioxidants suitable or customary for cosmetic and / or dermatological applications.
• water-soluble antioxidants such as vitamins, e.g. B. ascorbic acid and its derivatives.
• Preferred antioxidants are also vitamin E and its derivatives and vitamin A and its derivatives.
• the amount of the antioxidants (one or more compounds) in the preparations is preferably 0.001 to 30% by weight, particularly preferably 0.05 to 20% by weight, in particular 0.1 to 10% by weight, based on the total weight the preparation.
• vitamin E and / or its derivatives represent the antioxidant (s)
• vitamin A or vitamin A derivatives or carotenes or their derivatives represent the antioxidant or antioxidants, it is advantageous to add their respective concentrations in the range from 0.001 to 10% by weight, based on the total weight of the formulation choose.
• the cosmetic preparations according to the present invention contain cosmetic or dermatological active ingredients, preferred active ingredients being antioxidants which can protect the skin from oxidative stress.
• active substances in the sense of the present invention are natural active substances and / or their derivatives, such as.
• Recipes according to the invention which, for. B. known anti-wrinkle agents such as flavone Containing glycosides (in particular ⁇ -glycosylrutin), coenzyme Q10, vitamin E and / or derivatives and the like are particularly advantageous for the prophylaxis and treatment of cosmetic or dermatological skin changes, such as those described for. B. occur with skin aging (such as dryness, roughness and formation of dry lines, itching, reduced re-greasing (e.g. after washing), visible vasodilation (telangiectasias, cuperosis), flaccidity and formation of wrinkles and fine lines, local hyper- , Hypo and incorrect pigmentation (e.g. age spots), increased susceptibility to mechanical stress (e.g. cracking) and the like). They are also advantageous against the appearance of dry or rough skin.
• skin aging such as dryness, roughness and formation of dry lines, itching, reduced re-greasing (e.g. after washing), visible vasod
• formulations according to the invention can also have an anti-wrinkle effect or considerably increase the effect of known anti-wrinkle active ingredients. Accordingly, formulations in the sense of the present invention are particularly advantageous for the prophylaxis and treatment of cosmetic or dermatological skin changes such as those described, for example, in US Pat. B. occur in skin aging. They are also advantageous against the appearance of dry or rough skin.
• the present invention therefore relates to products for the care of the naturally aged skin and for the treatment of the consequential damage caused by light aging, in particular the phenomena listed above.
• the water phase of the preparations according to the invention can advantageously contain customary cosmetic auxiliaries, such as, for example, alcohols, in particular those having a low C number, preferably ethanol and / or isopropanol, diols or polyols having a low C number, and their ethers, preferably propylene glycol, glycerol, ethylene glycol, Ethylene glycol monoethyl or monobutyl ether, propylene glycol monomethyl, monoethyl or monobutyl ether, diethylene glycol monomethyl or monoethyl ether and analog products, polymers, foam stabilizers, electrolytes and moisturizers.
• customary cosmetic auxiliaries such as, for example, alcohols, in particular those having a low C number, preferably ethanol and / or isopropanol, diols or polyols having a low C number, and their ethers, preferably propylene glycol, glycerol, ethylene glycol,
• Moisturizers are substances or mixtures of substances that give cosmetic or dermatological preparations the property of releasing the moisture from the horny layer (also trans- reduce epidermal water loss (called TEWL) and / or have a positive effect on the hydration of the horny layer.
• TEWL trans- reduce epidermal water loss
• moisturizers for the purposes of the present invention are, for example, glycerin, lactic acid, pyrrolidone carboxylic acid and urea. Furthermore, it is particularly advantageous to use polymeric moisturizers from the group of water-soluble and / or water-swellable and / or water-gelable polysaccharides. Particularly advantageous are, for example, hyaluronic acid, chitosan and / or a fucose-rich polysaccharide, which is filed in the Chemical Abstracts under the registration number 178463-23-5 and z. B. under the name Fucogel®1000 from the company SOLABIA S.A. is available.
• the cosmetic and dermatological preparations according to the invention can contain dyes and / or color pigments, especially if they are in the form of decorative cosmetics.
• the dyes and pigments can be selected from the corresponding positive list in the Cosmetics Ordinance or the EC list of cosmetic colorants. In most cases, they are identical to the colorants approved for food.
• Advantageous color pigments are, for example, titanium dioxide, mica, iron oxides (for example Fe 2 O 3 , Fe 3 O 4 , FeO (OH)) and / or tin oxide.
• Advantageous dyes are, for example, carmine, Berlin blue, chrome oxide green, ultramarine blue and / or manganese violet. It is particularly advantageous to choose the dyes and / or color pigments from the Rowe Color Index, 3rd edition, Society of Dyers and Colorists, Bradford, England, 1971.
• the formulations according to the invention are in the form of products which are used on the face, it is advantageous to choose one or more substances from the following group as the dye: 2,4-dihydroxyazobenzene, 1- (2'-chloro-4 '-nitro-1'- phenylazo) -2-hydroxynaphthalene, ceres red, 2- (sulfo-1-naphthylazo) -1 -naphthol-4-sulfonic acid, calcium salt of 2-hydroxy-1, 2'-azonaphthalene-1 ' -sulfonic acid, calcium and barium salts of 1- (2-sulfo-4-methyl-1-phenylazo) -2-naphthylcarboxylic acid, calcium salt of 1- (2-sulfo-1-naphthylazo) -2-hydroxynaphthalene-3- carboxylic acid, aluminum salt of 1- (4-sulfo-1-phenylazo) -2-naphthol-6-sulfonic
• oil-soluble natural dyes such as. B. paprika extracts, ß-carotene or cochineal.
• Formulations containing pearlescent pigments are also advantageous for the purposes of the present invention.
• the types of pearlescent pigments listed below are particularly preferred:
• Natural pearlescent pigments such as. B.
• Monocrystalline pearlescent pigments such as B. bismuth oxychloride (BiOCI) 3rd layer substrate pigments: e.g. B. mica / metal oxide
• pearlescent pigments for example, powdered pigments or castor oil dispersions of bismuth oxychloride and / or titanium dioxide and bismuth oxychloride and / or titanium dioxide on mica. Particularly advantageous is e.g. B. the gloss pigment listed under CIN 77163.
• B the pearlescent pigments available from Merck under the trade names Timiron, Colorona or Dichrona.
• pearlescent pigments which are advantageous in the sense of the present invention can be obtained in numerous ways known per se.
• other substrates besides mica can be coated with other metal oxides, such as. B. silica and the like.
• metal oxides such as. B. silica and the like.
• Ronaspheren TiO 2 and Fe 2 O 3 coated SiO 2 particles
• Iron pearlescent pigments which are produced without the use of mica are particularly preferred. Such pigments are e.g. B. available under the trade name Sicopearl copper 1000 from BASF.
• effect pigments which are available from Flora Tech under the trade name Metasomes Standard / Glitter in various colors (yello, red, green, blue).
• the glitter particles are present in mixtures with various auxiliaries and dyes (such as, for example, the dyes with the Color Index (Cl) numbers 19140, 77007, 77289, 77491).
• the dyes and pigments can be present both individually and in a mixture and can be mutually coated, different color effects generally being produced by different coating thicknesses.
• the total amount of dyes and coloring pigments is advantageous from the range from Z. B. 0.1 wt .-% to 30 wt .-%, preferably from 0.5 to 15 wt .-%, in particular from 1, 0 to 10 wt .-%, each based on the total weight of the preparations.
• UV-A or UV-B filter substances are usually incorporated into day creams or makeup products.
• UV protection substances like antioxidants and, if desired, preservatives, also provide effective protection of the preparations themselves against spoilage.
• Cosmetic and dermatological preparations which are in the form of a sunscreen are also favorable.
• the preparations in the sense of the present invention preferably contain at least one further UV-A and / or UV-B filter substance in addition to one or more UV filter substances according to the invention.
• the formulations may, although not necessary, optionally also contain one or more organic and / or inorganic pigments as UV filter substances, which may be present in the water and / or the oil phase.
• the preparations according to the invention can also advantageously be in the form of so-called oil-free cosmetic or dermatological emulsions which contain a water phase and at least one UV filter substance which is liquid at room temperature and / or one or more silicone derivatives as a further phase.
• Oil-free formulations in the sense of the present invention can advantageously also contain other lipophilic components - such as lipophilic active ingredients.
• ICI homomenthyl salicylate
• Preferred inorganic pigments are metal oxides and / or other metal compounds which are sparingly soluble or insoluble in water, in particular oxides of titanium (TiO 2 ), zinc (ZnO), iron (e.g. Fe 2 O 3 ), zirconium (ZrO 2 ), silicon ( SiO 2 ), manganese (e.g. MnO), aluminum (Al 2 O 3 ), cerium (e.g. Ce 2 O 3 ), mixed oxides of the corresponding metals as well as mixtures of such oxides and the sulfate of barium (BaSO) ,
• the pigments can also advantageously be used in the form of commercially available oily or aqueous predispersions. Dispersing aids and / or solubilizing agents can advantageously be added to these predispersions.
• the pigments can advantageously be surface-treated (“coated”), for example, a hydrophilic, amphiphilic or hydrophobic character should be formed or retained.
• This surface treatment can consist in that the pigments are prepared with a thin hydrophilic and / or hydrophobic inorganic and / or organic layer
• the various surface coatings can also contain water for the purposes of the present invention.
• Inorganic surface coatings in the sense of the present invention can consist of aluminum oxide (Al 2 O 3 ), aluminum hydroxide Al (OH) 3 , or aluminum oxide hydrate (also: alumina, CAS no .: 1333-84-2), sodium hexametaphosphate (NaPO 3 ) 6 , sodium metaphosphate (NaPO 3 ) n , silicon dioxide (SiO 2 ) (also: silica, CAS No .: 7631-86-9), or iron oxide (Fe 2 O 3 ).
• Al 2 O 3 aluminum oxide
• Al aluminum hydroxide Al
• Al oxide hydrate also: alumina, CAS no .: 1333-84-2
• sodium hexametaphosphate (NaPO 3 ) 6 sodium metaphosphate (NaPO 3 ) n
• silicon dioxide SiO 2
• silica also: silica, CAS No .: 7631-86-9
• iron oxide Fe 2 O 3
• Organic surface coatings in the sense of the present invention can consist of vegetable or animal aluminum stearate, vegetable or animal stearic acid, lauric acid, dimethylpolysiloxane (also: dimethicone), methylpolysiloxane (methicone), simethicone (a mixture of dimethylpolysiloxane with an average chain length of 200 to 350 dimethylsiloxane Units and silica gel) or Alginic acid.
• dimethylpolysiloxane also: dimethicone
• methicone methylpolysiloxane
• simethicone a mixture of dimethylpolysiloxane with an average chain length of 200 to 350 dimethylsiloxane Units and silica gel
• Alginic acid Alginic acid.
• Zinc oxide particles and predispersions of zinc oxide particles suitable according to the invention are available under the following trade names from the companies listed:
• Suitable titanium dioxide particles and predispersions of titanium dioxide particles are available under the following trade names from the companies listed:
• An advantageous organic pigment for the purposes of the present invention is 2,2'-methylene-bis- (6- (2H-benzotriazol-2-yl) -4- (1,1,3,3-tetramethylbutyl) phenol) [INCI: bisoctyl-triazole], which is available under the trade name Tinosorb® M from CIBA-Chemicals GmbH.
• UV-A filter substances for the purposes of the present invention are dibenzoyl methane derivatives, in particular 4- (tert-butyl) -4'-methoxydibenzoyl methane (CAS No. 70356-09-1), which is sold by Givaudan under the brand name Parsol ® 1789 and is sold by Merck under the trade name Eusolex® 9020.
• dibenzoyl methane derivatives in particular 4- (tert-butyl) -4'-methoxydibenzoyl methane (CAS No. 70356-09-1), which is sold by Givaudan under the brand name Parsol ® 1789 and is sold by Merck under the trade name Eusolex® 9020.
• UV filter substances in the sense of the present invention are sulfonated, water-soluble UV filters, such as.
• B. Phenylene-1,4-bis (2-benzimidazyl) -3,3'-5,5'-tetrasulfonic acid and its salts, especially the corresponding sodium, potassium or triethanolammonium salts, in particular phenylene-1,4 -bis- (2-benzimidazyl) -3,3'-5,5'-tetrasulfonic acid bis-sodium salt with the INCI name bisimidazylate (CAS No .: 180898-37-7), which, for example, under the trade name Neo Heliopan AP at Haarmann &
• Benzene-1,4-di (2-oxo-3-bornylidenemethyl-10-sulfonic acid) is called.
• Benzene-1,4-di (2-oxo-3-bornylidenemethyl-10-sulfonic acid) has the INCI name Terephtalidene Dicampher Sulfonic Acid (CAS No .: 90457-82-2) and is, for example, under the trade name Mexoryl SX from available from Chimex; • Sulfonic acid derivatives of 3-benzylidene camphor, such as.
• Advantageous UV filter substances in the sense of the present invention are also so-called broadband filters, i.e. Filter substances that absorb both UV-A and UV-B radiation.
• Advantageous broadband filters or UV-B filter substances are, for example, triazine derivatives, such as. B. • 2,4-bis - ⁇ [4- (2-Ethylhexyloxy) -2-hydroxy] phenyl ⁇ -6- (4-methoxyphenyl) -1,3,5-triazine
• Tinosorb® S (INCI: Aniso Triazin), which is sold under the trade name Tinosorb® S by
• Dioctylbutylamidotriazon (INCI: Dioctylbutamidotriazone), which is available under the trade name UVASORB HEB from Sigma 3V; • 4,4 ', 4 "- (1,3,5-triazine-2,4,6-triyltriimino) tris-benzoic acid tris (2-ethylhexyl ester), synonymous: 2,4,6-tris [anilino - (p-carbo-2'-ethyl-1 , -hexyloxy)] - 1, 3,5-triazine (INCI: Octyl Triazone), which is sold by BASF Aktiengesellschaft under the trade name UVINUL® T 150.
• An advantageous broadband filter for the purposes of the present invention is 2,2'-methylene-bis- (6- (2H-benzotriazol-2-yl) -4- (1,1,3,3-tetramethylbutyl) phenol) , which is available under the trade name Tinosorb® M from CIBA-Chemicals GmbH.
• Another advantageous broadband filter for the purposes of the present invention is 2- (2H-benzotriazol-2-yl) -4-methyl-6- [2-methyl-3- [1, 3,3,3-tetramethyl-1 - [( trimethylsilyl) oxy] disiloxanyl] propyl] phenol (CAS No .: 155633-54-8) with the INCI name Drometrizole Trisiloxane.
• the UV filter substances can be oil-soluble or water-soluble.
• Advantageous oil-soluble filter substances are e.g. B .:
• 3-benzylidene camphor derivatives preferably 3- (4-methylbenzylidene) camphor, 3-benzylidene camphor;
• 4-aminobenzoic acid derivatives preferably 4- (dimethylamino) benzoic acid (2-ethylhexyl) ester, 4- (dimethylamino) benzoic acid amyl ester;
• esters of benzalmalonic acid preferably 4-methoxybenzalmalonic acid di (2-ethylhexyl) ester
• esters of cinnamic acid preferably 4-methoxycinnamic acid (2-ethylhexyl) ester, 4-methoxycinnamic acid isopentyl ester;
• benzophenone preferably 2-hydroxy-4-methoxybenzophenone, 2-hydroxy-4-methoxy-4'-methylbenzophenone, 2,2'-dihydroxy-4-methoxybenzophenone and
• Advantageous water-soluble filter substances are e.g. B .:
• Sulfonic acid derivatives of 3-benzylidene camphor such as. B. 4- (2-oxo-3-bomylidene methyl) benzenesulfonic acid, 2-methyl-5- (2-oxo-3-bornylidene methyl) sulfonic acid and their
• a further light protection filter substance according to the invention to be used advantageously is ethylhexyl-2-cyano-3,3-diphenylacrylate, obtainable (octocrylene) from BASF under the name Uvinul ® N 539th
• Particularly advantageous preparations in the sense of the present invention which are distinguished by a high or very high UV-A protection, preferably contain a plurality of UV-A and / or broadband filters, in particular dibenzoylmethane derivatives [for example 4- (tert-butyl) -4'-methoxydibenzoylmethane], benzotriazole derivatives [e.g.
• Emulsion II% by weight% by volume Emulsion II% by weight% by volume
• Predispersion of the inorganic gel formers and swelling of the hydrocolloid with stirring in the water phase Combination of the fat phase heated to 80 ° C with the water phase heated to 75 ° C. Add the particulate hydrophobic, hydrophobized solid substances with stirring. Homogenization using a gear rim dispersion machine (rotor-stator principle) at 65 ° C. 45 min stirring in the Becomix with fumigation with nitrous oxide at 0.7 bar with cooling to 30 ° C. Addition of additives at 30 ° C (perfume, active ingredients). Homogenization using a gear rim dispersion machine (rotor-stator principle) at 26 ° C.
• Vitamin E acetate 2.00
• Predispersion of the inorganic gelling agent (hectorite) and swelling of the hydrocolloids while stirring in the water phase Predispersion of quaternium 18 hectorite in the hot fat phase. Association of the Fet Ucherschutzfilterpha- heated to 78 ° C se with the water / light protection filter phase heated to 75 ° C. Add the particulate hydrophobic, hydrophobized solid substances with stirring. Homogenization using a gear rim dispersion machine (rotor-stator principle) at 65 ° C. 45 min stirring in the Becomix while gassing with helium at 1 bar with cooling to 30 ° C. Add the additives at 30 ° C (perfume). Homogenization using a gear rim dispersion machine (rotor-stator principle) at 23 ° C.

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• 2001
  • 2001-09-07 DE DE10144061A patent/DE10144061A1/de not_active Withdrawn
• 2002
  • 2002-09-06 WO PCT/EP2002/009981 patent/WO2003022238A1/de not_active Application Discontinuation
  • 2002-09-06 EP EP02774576A patent/EP1435902A1/de not_active Withdrawn
  • 2002-09-06 JP JP2003526368A patent/JP2005506325A/ja active Pending
• 2004
  • 2004-03-08 US US10/796,850 patent/US20040241105A1/en not_active Abandoned

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