EP1425395A4 - Systems and methods for delivering interferon to a subject - Google Patents

Systems and methods for delivering interferon to a subject

Info

Publication number
EP1425395A4
EP1425395A4 EP01998303A EP01998303A EP1425395A4 EP 1425395 A4 EP1425395 A4 EP 1425395A4 EP 01998303 A EP01998303 A EP 01998303A EP 01998303 A EP01998303 A EP 01998303A EP 1425395 A4 EP1425395 A4 EP 1425395A4
Authority
EP
European Patent Office
Prior art keywords
subject
systems
methods
delivering interferon
interferon
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP01998303A
Other languages
German (de)
French (fr)
Other versions
EP1425395A2 (en
Inventor
Amit Gal-On
Yoel Moshe Shiboleth
Tsachi Arazi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Virogene Ltd
Original Assignee
Virogene Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Virogene Ltd filed Critical Virogene Ltd
Publication of EP1425395A2 publication Critical patent/EP1425395A2/en
Publication of EP1425395A4 publication Critical patent/EP1425395A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8202—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation by biological means, e.g. cell mediated or natural vector
    • C12N15/8203—Virus mediated transformation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5256—Virus expressing foreign proteins
EP01998303A 2000-11-28 2001-11-28 Systems and methods for delivering interferon to a subject Withdrawn EP1425395A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25313600P 2000-11-28 2000-11-28
US253136P 2000-11-28
PCT/IL2001/001099 WO2002043650A2 (en) 2000-11-28 2001-11-28 Systems and methods for delivering interferon to a subject

Publications (2)

Publication Number Publication Date
EP1425395A2 EP1425395A2 (en) 2004-06-09
EP1425395A4 true EP1425395A4 (en) 2006-03-01

Family

ID=22959018

Family Applications (1)

Application Number Title Priority Date Filing Date
EP01998303A Withdrawn EP1425395A4 (en) 2000-11-28 2001-11-28 Systems and methods for delivering interferon to a subject

Country Status (4)

Country Link
EP (1) EP1425395A4 (en)
CN (1) CN1575336A (en)
AU (1) AU2002221011A1 (en)
WO (1) WO2002043650A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8022270B2 (en) * 2000-07-31 2011-09-20 Biolex Therapeutics, Inc. Expression of biologically active polypeptides in duckweed
US7959910B2 (en) 2000-07-31 2011-06-14 Biolex Therapeutics, Inc. C-terminally truncated interferon alpha variants
US20060024272A1 (en) 2004-07-29 2006-02-02 Large Scale Biology Corporation C-terminally truncated interferon

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999051749A2 (en) * 1998-04-07 1999-10-14 State Of Israel/Ministry Of Agriculture Recombinant potyvirus construct and use thereof
WO2002059334A1 (en) * 2001-01-24 2002-08-01 Virogene Ltd. Vectors capable of imparting herbicide resistance and viral cross protection and methods

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4956282A (en) * 1985-07-29 1990-09-11 Calgene, Inc. Mammalian peptide expression in plant cells
US5866787A (en) * 1993-03-08 1999-02-02 Cleveland Clinic Foundation Transgenic plants co-expressing a functional human 2-5A system

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999051749A2 (en) * 1998-04-07 1999-10-14 State Of Israel/Ministry Of Agriculture Recombinant potyvirus construct and use thereof
WO2002059334A1 (en) * 2001-01-24 2002-08-01 Virogene Ltd. Vectors capable of imparting herbicide resistance and viral cross protection and methods

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
ARAZI T ET AL: "Engineering zucchini yellow mosaic potyvirus as a non-pathogenic vector for expression of heterologous proteins in cucurbits", JOURNAL OF BIOTECHNOLOGY, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 87, no. 1, 27 April 2001 (2001-04-27), pages 67 - 82, XP004231297, ISSN: 0168-1656 *
GAL-ON A ET AL: "High level expression of foreign genes by virus vector (ZYMV) in cucurbits", PHYTOPARASITICA, PRIEL PUBLISHERS, REHOVOT, IL, vol. 27, no. 2, 1999, pages 165, XP002341475, ISSN: 0334-2123 *
GAL-ON ET AL: "A zucchini yellow mosaic virus coat protein gene mutation restores aphid transmissibility but has no effect on amplification", JOURNAL OF GENERAL VIROLOGY, SOCIETY FOR GENERAL MICROBIOLOGY, READING, GB, vol. 73, 1992, pages 2183 - 2187, XP002118198, ISSN: 0022-1317 *
HUET ET AL: "Mutations in the helper component protease gene of zucchini yellow mosaic virus affect its ability to mediate aphid transmissibility", JOURNAL OF GENERAL VIROLOGY, SOCIETY FOR GENERAL MICROBIOLOGY, READING, GB, vol. 75, 1994, pages 1407 - 1414, XP002118196, ISSN: 0022-1317 *
THE 20TH CONGRESS OF THE ISRAELI PHYTOPATHOLOGICAL SOCIETY, 15 February 1999 (1999-02-15), Bet Dagan, Israel *

Also Published As

Publication number Publication date
EP1425395A2 (en) 2004-06-09
WO2002043650A2 (en) 2002-06-06
AU2002221011A1 (en) 2002-06-11
CN1575336A (en) 2005-02-02
WO2002043650A3 (en) 2004-02-26

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Legal Events

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Effective date: 20060411