EP1373547A4 - Kontrolle von glycoformen in igg - Google Patents

Kontrolle von glycoformen in igg

Info

Publication number
EP1373547A4
EP1373547A4 EP02725443A EP02725443A EP1373547A4 EP 1373547 A4 EP1373547 A4 EP 1373547A4 EP 02725443 A EP02725443 A EP 02725443A EP 02725443 A EP02725443 A EP 02725443A EP 1373547 A4 EP1373547 A4 EP 1373547A4
Authority
EP
European Patent Office
Prior art keywords
glycoforms
igg
control
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP02725443A
Other languages
English (en)
French (fr)
Other versions
EP1373547A1 (de
Inventor
Ruth L Devries
Thomas B Vickroy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of EP1373547A1 publication Critical patent/EP1373547A1/de
Publication of EP1373547A4 publication Critical patent/EP1373547A4/de
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
    • C07K2317/41—Glycosylation, sialylation, or fucosylation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP02725443A 2001-03-27 2002-03-27 Kontrolle von glycoformen in igg Ceased EP1373547A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US27902601P 2001-03-27 2001-03-27
US279026P 2001-03-27
PCT/US2002/009998 WO2002076578A1 (en) 2001-03-27 2002-03-27 Control of glycoforms in igg

Publications (2)

Publication Number Publication Date
EP1373547A1 EP1373547A1 (de) 2004-01-02
EP1373547A4 true EP1373547A4 (de) 2006-01-18

Family

ID=23067363

Family Applications (1)

Application Number Title Priority Date Filing Date
EP02725443A Ceased EP1373547A4 (de) 2001-03-27 2002-03-27 Kontrolle von glycoformen in igg

Country Status (4)

Country Link
EP (1) EP1373547A4 (de)
JP (1) JP2005509403A (de)
AU (1) AU2002256005A1 (de)
WO (1) WO2002076578A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2682738A1 (en) * 2007-04-16 2008-10-23 Momenta Pharmaceuticals, Inc. Defined glycoprotein products and related methods
BRPI0815576A2 (pt) 2007-08-20 2015-02-18 Glaxo Group Ltd Método para produzir uma linha celular que produz uma proteína terapêutica, segunda linha celular transformada com uma segunda seqüência de polinucleotídeos, vetor, cassete de expressão amplificado, linha celular ou sua progênie, e, anticorpo.
DK2493922T3 (en) 2009-10-26 2017-04-24 Hoffmann La Roche Process for preparing a glycosylated immunoglobulin
CN102869784A (zh) 2010-04-07 2013-01-09 动量制药公司 高甘露糖聚糖
CN102858954A (zh) 2010-04-26 2013-01-02 诺瓦提斯公司 改进的细胞培养方法
EP2686671A4 (de) 2011-03-12 2015-06-24 Momenta Pharmaceuticals Inc N-acetylhexosamin-haltige n-glykane in glycoproteinprodukten
EP2686423A4 (de) 2011-03-14 2015-01-28 Nat Res Council Canada Verfahren zur herstellung von viren in zellen
WO2012149197A2 (en) 2011-04-27 2012-11-01 Abbott Laboratories Methods for controlling the galactosylation profile of recombinantly-expressed proteins
US9181572B2 (en) 2012-04-20 2015-11-10 Abbvie, Inc. Methods to modulate lysine variant distribution
US9067990B2 (en) 2013-03-14 2015-06-30 Abbvie, Inc. Protein purification using displacement chromatography
WO2013158279A1 (en) 2012-04-20 2013-10-24 Abbvie Inc. Protein purification methods to reduce acidic species
WO2013181575A2 (en) 2012-06-01 2013-12-05 Momenta Pharmaceuticals, Inc. Methods related to denosumab
US9512214B2 (en) 2012-09-02 2016-12-06 Abbvie, Inc. Methods to control protein heterogeneity
EP2830651A4 (de) 2013-03-12 2015-09-02 Abbvie Inc An humanes tnf-alpha bindende humane antikörper und verfahren zur herstellung davon
WO2014151878A2 (en) 2013-03-14 2014-09-25 Abbvie Inc. Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosacharides
US9017687B1 (en) 2013-10-18 2015-04-28 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same using displacement chromatography
EP2855533A4 (de) 2013-03-15 2015-11-25 Momenta Pharmaceuticals Inc Verfahren in zusammenhang mit ctla4-fc-fusionsproteinen
US10464996B2 (en) 2013-05-13 2019-11-05 Momenta Pharmaceuticals, Inc. Methods for the treatment of neurodegeneration
JP6563910B2 (ja) 2013-07-04 2019-08-21 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 血清サンプル中の抗薬物抗体を検出するための干渉抑制イムノアッセイ
AR096839A1 (es) * 2013-07-06 2016-02-03 Cadila Healthcare Ltd Proceso mejorado para la producción de anticuerpos monoclonales
US9598667B2 (en) 2013-10-04 2017-03-21 Abbvie Inc. Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins
WO2015057622A1 (en) 2013-10-16 2015-04-23 Momenta Pharmaceuticals, Inc. Sialylated glycoproteins
US9181337B2 (en) 2013-10-18 2015-11-10 Abbvie, Inc. Modulated lysine variant species compositions and methods for producing and using the same
US9085618B2 (en) 2013-10-18 2015-07-21 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same
US20150139988A1 (en) 2013-11-15 2015-05-21 Abbvie, Inc. Glycoengineered binding protein compositions
TR201610497T1 (tr) * 2014-01-29 2017-06-21 Lg Chemical Ltd Rekombi̇nant protei̇n galaktosi̇lasyonunu kültür ortaminin opti̇mi̇zasyonu vasitasiyla modüle etme yöntemi̇

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999028455A1 (de) * 1997-12-03 1999-06-10 Roche Diagnostics Gmbh Verfahren zur herstellung von polypeptiden mit geeigneter glykosilierung
WO2000065070A2 (en) * 1999-04-26 2000-11-02 Genentech, Inc. Cell culture process for glycoproteins

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1304918A (en) * 1919-05-27 Exlter medium ob other abticiie of mauufactitbe
US1898027A (en) * 1929-01-10 1933-02-21 Charles A Winslow Air filter
US2271662A (en) * 1939-01-17 1942-02-03 Rubissow George Alexis Filtering element and new method for its manufacture
US2217370A (en) * 1939-08-08 1940-10-08 Socony Vacuum Oil Co Inc Screen wrapped perforated liner pipe
US3383278A (en) * 1967-09-27 1968-05-14 Appleton Mills Adjustable woven fabric
US3502116A (en) * 1967-11-29 1970-03-24 Nat Standard Co Woven filter cloth
US4048075A (en) * 1974-05-06 1977-09-13 The Carborundum Company Filter cartridge
US5256291A (en) * 1992-04-16 1993-10-26 Cagle William S Screen for filtering undesirable particles from a liquid
US5673483A (en) * 1994-05-25 1997-10-07 Morton International, Inc. Method for constructing an inflator filter made of wrapped mesh
US5711879A (en) * 1996-03-04 1998-01-27 American Metal Fibers Radial-flow filter and method of manufacture
ATE229366T1 (de) * 1999-02-02 2002-12-15 Bekaert Sa Nv Bandgewickelte filterpatrone

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999028455A1 (de) * 1997-12-03 1999-06-10 Roche Diagnostics Gmbh Verfahren zur herstellung von polypeptiden mit geeigneter glykosilierung
WO2000065070A2 (en) * 1999-04-26 2000-11-02 Genentech, Inc. Cell culture process for glycoproteins

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO02076578A1 *

Also Published As

Publication number Publication date
EP1373547A1 (de) 2004-01-02
WO2002076578A1 (en) 2002-10-03
JP2005509403A (ja) 2005-04-14
WO2002076578A9 (en) 2003-03-06
AU2002256005A1 (en) 2002-10-08

Similar Documents

Publication Publication Date Title
EP1373547A4 (de) Kontrolle von glycoformen in igg
GB2390383B (en) Flow control regulation methods
EP1454085A4 (de) Prozesssteuerventil
GB0104995D0 (en) Artificial morpho-functional multiped and motion controller therefor
EP1432444A4 (de) Anti-a-beta-antikörper
HK1074206A1 (en) Anti-trail-r antibodies
GB0120209D0 (en) Adjustable valve control system
AU2001256325A1 (en) Human and humanized fap-alpha-specific antibodies
AU2002365649A8 (en) Anti-dota antibody
HK1054119A1 (en) Position control method
PL367329A1 (en) Methods for reducing immunogenicity of polypeptides
GB0116970D0 (en) Flow controller
AU2002357934A8 (en) Humanized lactoferrin and uses thereof
GB0119712D0 (en) Control valves
GB0104299D0 (en) Immunoglobulin control region
GB0414019D0 (en) Flow control
HU2352U (en) Comfortable ear-plug
GB2374730B (en) Control
TW506282U (en) Magnetically controlled adjuster
TW492296U (en) Multifunctional pillow for children
EP1444250A4 (de) Chimäres groel-protein und impfstoff
GB0112927D0 (en) Control valve
GB0122585D0 (en) Control of an interactive application
IL161278A0 (en) Flow reducing implant
GB0105327D0 (en) Multi-metric valve controller

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20030922

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

AX Request for extension of the european patent

Extension state: AL LT LV MK RO SI

A4 Supplementary search report drawn up and despatched

Effective date: 20051202

RIC1 Information provided on ipc code assigned before grant

Ipc: C07K 16/00 19950101ALI20051128BHEP

Ipc: C12P 21/00 19800101AFI20051128BHEP

17Q First examination report despatched

Effective date: 20060309

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED

18R Application refused

Effective date: 20090216