EP1358196A4 - Human hyperpolarization-activated cyclic nucleotide-gated cation channel hcn3 - Google Patents

Human hyperpolarization-activated cyclic nucleotide-gated cation channel hcn3

Info

Publication number
EP1358196A4
EP1358196A4 EP01991006A EP01991006A EP1358196A4 EP 1358196 A4 EP1358196 A4 EP 1358196A4 EP 01991006 A EP01991006 A EP 01991006A EP 01991006 A EP01991006 A EP 01991006A EP 1358196 A4 EP1358196 A4 EP 1358196A4
Authority
EP
European Patent Office
Prior art keywords
hcn3
cyclic nucleotide
cation channel
gated cation
activated cyclic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP01991006A
Other languages
German (de)
French (fr)
Other versions
EP1358196A2 (en
Inventor
Kimberly L Folander
Yuan Liu
Edward Mckenna
Richard J Swanson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of EP1358196A2 publication Critical patent/EP1358196A2/en
Publication of EP1358196A4 publication Critical patent/EP1358196A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
EP01991006A 2000-12-20 2001-12-14 Human hyperpolarization-activated cyclic nucleotide-gated cation channel hcn3 Withdrawn EP1358196A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25680000P 2000-12-20 2000-12-20
US256800P 2000-12-20
PCT/US2001/047903 WO2002050300A2 (en) 2000-12-20 2001-12-14 Human hyperpolarization-activated cyclic nucleotide-gated cation channel hcn3

Publications (2)

Publication Number Publication Date
EP1358196A2 EP1358196A2 (en) 2003-11-05
EP1358196A4 true EP1358196A4 (en) 2004-11-03

Family

ID=22973626

Family Applications (1)

Application Number Title Priority Date Filing Date
EP01991006A Withdrawn EP1358196A4 (en) 2000-12-20 2001-12-14 Human hyperpolarization-activated cyclic nucleotide-gated cation channel hcn3

Country Status (3)

Country Link
EP (1) EP1358196A4 (en)
CA (1) CA2432274A1 (en)
WO (1) WO2002050300A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8859273B2 (en) * 2003-12-24 2014-10-14 Medtronic, Inc. Methods of using HCN genes to treat cardiac arrhythmias
WO2013183985A1 (en) * 2012-06-05 2013-12-12 Erasmus University Medical Center Rotterdam Method of treating cognitive impairment and compounds for use therein

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002004520A2 (en) * 2000-07-07 2002-01-17 Incyte Genomics, Inc. Transporters and ion channels
WO2002100408A2 (en) * 2001-06-08 2002-12-19 Ortho-Mcneil Pharmaceutical, Inc. Treating neuropathic/inflammatory pain by targeting a composition (e.g. zd7288) to hcn pacemaker channels

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1169433A4 (en) * 1999-04-15 2003-01-02 Icagen Inc Human hac3

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002004520A2 (en) * 2000-07-07 2002-01-17 Incyte Genomics, Inc. Transporters and ion channels
WO2002100408A2 (en) * 2001-06-08 2002-12-19 Ortho-Mcneil Pharmaceutical, Inc. Treating neuropathic/inflammatory pain by targeting a composition (e.g. zd7288) to hcn pacemaker channels

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
CLAPHAM DAVID E: "Not so funny anymore: Pacing channels are cloned", NEURON, CAMBRIDGE, MA, US, vol. 21, no. 1, July 1998 (1998-07-01), pages 5 - 7, XP002177234 *
DATABASE EMBL 18 June 1998 (1998-06-18), "Mus musculus mRNA for hyperpolarization-activated cation channel HAC3", XP002294374, retrieved from EBI Database accession no. AJ225124 *
DATABASE EMBL 23 May 2000 (2000-05-23), "Homo sapiens mRNA for KIAA1535 protein, partial cds", XP002294373, retrieved from EBI Database accession no. AB040968 *
LUDWIG A ET AL: "A FAMILY OF HYPERPOLARIZATIONACTIVATED MAMMALIAN CATION CHANNELS", NATURE, MACMILLAN JOURNALS LTD. LONDON, GB, vol. 393, 11 June 1998 (1998-06-11), pages 587 - 591, XP002109145, ISSN: 0028-0836 *
NAGASE T ET AL: "PREDICTION OF THE CODING SEQUENCES OF UNIDENTIFIED HUMAN GENES.17. THE COMPLETE SEQUENCES OF 100 NEW CDNA CLONES FROM BRAIN WHICH CODE FOR LARGE PROTEINS IN VITRO", DNA RESEARCH, UNIVERSAL ACADEMY PRESS, JP, vol. 7, April 2000 (2000-04-01), pages 143 - 150, XP008010899, ISSN: 1340-2838 *
SANTORO BINA ET AL: "The HCN gene family: Molecular basis of the hyperpolarization-activa ted pacemaker channels", ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, NEW YORK ACADEMY OF SCIENCES, NEW YORK, NY, US, vol. 868, 30 April 1999 (1999-04-30), pages 741 - 764, XP002177233, ISSN: 0077-8923 *

Also Published As

Publication number Publication date
WO2002050300A2 (en) 2002-06-27
CA2432274A1 (en) 2002-06-27
EP1358196A2 (en) 2003-11-05
WO2002050300A3 (en) 2003-09-04

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Legal Events

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