EP1358196A4 - Menschlicher hyperpolarisationsaktivierter, durch cyclische nukleotide gesteuerter kationenkanal hcn3 - Google Patents

Menschlicher hyperpolarisationsaktivierter, durch cyclische nukleotide gesteuerter kationenkanal hcn3

Info

Publication number
EP1358196A4
EP1358196A4 EP01991006A EP01991006A EP1358196A4 EP 1358196 A4 EP1358196 A4 EP 1358196A4 EP 01991006 A EP01991006 A EP 01991006A EP 01991006 A EP01991006 A EP 01991006A EP 1358196 A4 EP1358196 A4 EP 1358196A4
Authority
EP
European Patent Office
Prior art keywords
hcn3
cyclic nucleotide
cation channel
gated cation
activated cyclic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP01991006A
Other languages
English (en)
French (fr)
Other versions
EP1358196A2 (de
Inventor
Kimberly L Folander
Yuan Liu
Edward Mckenna
Richard J Swanson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of EP1358196A2 publication Critical patent/EP1358196A2/de
Publication of EP1358196A4 publication Critical patent/EP1358196A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
EP01991006A 2000-12-20 2001-12-14 Menschlicher hyperpolarisationsaktivierter, durch cyclische nukleotide gesteuerter kationenkanal hcn3 Withdrawn EP1358196A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25680000P 2000-12-20 2000-12-20
US256800P 2000-12-20
PCT/US2001/047903 WO2002050300A2 (en) 2000-12-20 2001-12-14 Human hyperpolarization-activated cyclic nucleotide-gated cation channel hcn3

Publications (2)

Publication Number Publication Date
EP1358196A2 EP1358196A2 (de) 2003-11-05
EP1358196A4 true EP1358196A4 (de) 2004-11-03

Family

ID=22973626

Family Applications (1)

Application Number Title Priority Date Filing Date
EP01991006A Withdrawn EP1358196A4 (de) 2000-12-20 2001-12-14 Menschlicher hyperpolarisationsaktivierter, durch cyclische nukleotide gesteuerter kationenkanal hcn3

Country Status (3)

Country Link
EP (1) EP1358196A4 (de)
CA (1) CA2432274A1 (de)
WO (1) WO2002050300A2 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8859273B2 (en) 2003-12-24 2014-10-14 Medtronic, Inc. Methods of using HCN genes to treat cardiac arrhythmias
WO2013183985A1 (en) * 2012-06-05 2013-12-12 Erasmus University Medical Center Rotterdam Method of treating cognitive impairment and compounds for use therein

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002004520A2 (en) * 2000-07-07 2002-01-17 Incyte Genomics, Inc. Transporters and ion channels
WO2002100408A2 (en) * 2001-06-08 2002-12-19 Ortho-Mcneil Pharmaceutical, Inc. Treating neuropathic/inflammatory pain by targeting a composition (e.g. zd7288) to hcn pacemaker channels

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4456800A (en) * 1999-04-15 2000-11-02 Icagen, Inc. Human hac3

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002004520A2 (en) * 2000-07-07 2002-01-17 Incyte Genomics, Inc. Transporters and ion channels
WO2002100408A2 (en) * 2001-06-08 2002-12-19 Ortho-Mcneil Pharmaceutical, Inc. Treating neuropathic/inflammatory pain by targeting a composition (e.g. zd7288) to hcn pacemaker channels

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
CLAPHAM DAVID E: "Not so funny anymore: Pacing channels are cloned", NEURON, CAMBRIDGE, MA, US, vol. 21, no. 1, July 1998 (1998-07-01), pages 5 - 7, XP002177234 *
DATABASE EMBL 18 June 1998 (1998-06-18), "Mus musculus mRNA for hyperpolarization-activated cation channel HAC3", XP002294374, retrieved from EBI Database accession no. AJ225124 *
DATABASE EMBL 23 May 2000 (2000-05-23), "Homo sapiens mRNA for KIAA1535 protein, partial cds", XP002294373, retrieved from EBI Database accession no. AB040968 *
LUDWIG A ET AL: "A FAMILY OF HYPERPOLARIZATIONACTIVATED MAMMALIAN CATION CHANNELS", NATURE, MACMILLAN JOURNALS LTD. LONDON, GB, vol. 393, 11 June 1998 (1998-06-11), pages 587 - 591, XP002109145, ISSN: 0028-0836 *
NAGASE T ET AL: "PREDICTION OF THE CODING SEQUENCES OF UNIDENTIFIED HUMAN GENES.17. THE COMPLETE SEQUENCES OF 100 NEW CDNA CLONES FROM BRAIN WHICH CODE FOR LARGE PROTEINS IN VITRO", DNA RESEARCH, UNIVERSAL ACADEMY PRESS, JP, vol. 7, April 2000 (2000-04-01), pages 143 - 150, XP008010899, ISSN: 1340-2838 *
SANTORO BINA ET AL: "The HCN gene family: Molecular basis of the hyperpolarization-activa ted pacemaker channels", ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, NEW YORK ACADEMY OF SCIENCES, NEW YORK, NY, US, vol. 868, 30 April 1999 (1999-04-30), pages 741 - 764, XP002177233, ISSN: 0077-8923 *

Also Published As

Publication number Publication date
EP1358196A2 (de) 2003-11-05
WO2002050300A3 (en) 2003-09-04
WO2002050300A2 (en) 2002-06-27
CA2432274A1 (en) 2002-06-27

Similar Documents

Publication Publication Date Title
GB2393661B (en) Lancet
EP1378520A4 (de) Trispezifischer antikörper mit cyclischem einzelstrang
EP1408852A4 (de) Lanzettenvorrichtung für den einmalgebrauch
HU0200378D0 (en) Pulverulent composition for bleaching human keratin fibres
HK1080376A1 (en) Cosmetic preparation
EP1402066A4 (de) Schmerzbehandlung mit durch hyperpolarisation aktivierten, durch zyklisches nukleotid gesteuerten kanälen als angriffspunkt
EP1570832A4 (de) Kosmetisches haarpräparat
AU2002360487A8 (en) Acyclovir-peptide analogs
AU2003219933A8 (en) Expression system for human brain-specific voltage-gated sodium channel, type 1
GB0120238D0 (en) Sodium channel regulators and modulators
HK1053132B (zh) 硅氧烷凝膠組合物
EP1358196A4 (de) Menschlicher hyperpolarisationsaktivierter, durch cyclische nukleotide gesteuerter kationenkanal hcn3
AU2003297693A8 (en) Splice variant of human sodium iii channel (hnaiii18)
PL363921A1 (en) Skin moisturizing composition
AU148069S (en) Hair colour analyser
AU2002354842A1 (en) Novel human proton-gated channels
GB2377581B (en) Communication device using bone conduction
GB0127877D0 (en) Skin preparation
AU2002249304A8 (en) Novel human gnrh receptor
GB0127906D0 (en) Cap for cooling human scalp
EP1423568A4 (de) Alternative zur viskosebeflockung
AU2002218516A1 (en) Novel human chloride channel
AU2002252428A1 (en) Human potassium channel
GB0115363D0 (en) Ion channel modulators
TW557698U (en) Hair comb for massaging scalp

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

17P Request for examination filed

Effective date: 20040304

A4 Supplementary search report drawn up and despatched

Effective date: 20040921

17Q First examination report despatched

Effective date: 20041025

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20051029