EP1351734A2 - Dry powder inhaler - Google Patents
Dry powder inhalerInfo
- Publication number
- EP1351734A2 EP1351734A2 EP01992208A EP01992208A EP1351734A2 EP 1351734 A2 EP1351734 A2 EP 1351734A2 EP 01992208 A EP01992208 A EP 01992208A EP 01992208 A EP01992208 A EP 01992208A EP 1351734 A2 EP1351734 A2 EP 1351734A2
- Authority
- EP
- European Patent Office
- Prior art keywords
- dose
- sheet
- pressurized air
- substrate
- trough
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229940112141 dry powder inhaler Drugs 0.000 title claims abstract description 8
- 239000000843 powder Substances 0.000 claims abstract description 46
- 239000002245 particle Substances 0.000 claims abstract description 13
- 239000000758 substrate Substances 0.000 claims description 59
- 239000003814 drug Substances 0.000 claims description 11
- 239000000463 material Substances 0.000 claims description 9
- 238000000034 method Methods 0.000 claims description 6
- 230000004913 activation Effects 0.000 claims description 5
- 229920002799 BoPET Polymers 0.000 claims description 3
- 239000005041 Mylar™ Substances 0.000 claims description 3
- 230000001681 protective effect Effects 0.000 claims description 2
- 238000007664 blowing Methods 0.000 claims 1
- 239000007787 solid Substances 0.000 description 4
- 229940079593 drug Drugs 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- -1 polypropylene Polymers 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- 239000004698 Polyethylene Substances 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 229920000122 acrylonitrile butadiene styrene Polymers 0.000 description 1
- 239000004676 acrylonitrile butadiene styrene Substances 0.000 description 1
- 239000000443 aerosol Substances 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 230000002939 deleterious effect Effects 0.000 description 1
- 238000012377 drug delivery Methods 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- 239000010419 fine particle Substances 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 239000008188 pellet Substances 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 238000009877 rendering Methods 0.000 description 1
- 230000000241 respiratory effect Effects 0.000 description 1
- 230000000153 supplemental effect Effects 0.000 description 1
- 230000001960 triggered effect Effects 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B17/00—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
- B05B17/04—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
- B05B17/06—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
- B05B17/0692—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by a fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/001—Particle size control
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/005—Sprayers or atomisers specially adapted for therapeutic purposes using ultrasonics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/02—Sprayers or atomisers specially adapted for therapeutic purposes operated by air or other gas pressure applied to the liquid or other product to be sprayed or atomised
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0005—Details of inhalators; Constructional features thereof with means for agitating the medicament
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
- A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
- A61M15/0048—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged in a plane, e.g. on diskettes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
Abstract
Description
Claims
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CY20081100056T CY1108525T1 (en) | 2001-01-08 | 2008-01-15 | DRY POWDER FUEL |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US756313 | 2001-01-08 | ||
US09/756,313 US6626173B2 (en) | 2001-01-08 | 2001-01-08 | Dry powder inhaler |
PCT/US2001/049409 WO2002053215A2 (en) | 2001-01-08 | 2001-12-18 | Dry powder inhaler |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1351734A2 true EP1351734A2 (en) | 2003-10-15 |
EP1351734B1 EP1351734B1 (en) | 2007-11-14 |
Family
ID=25042937
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP01992208A Expired - Lifetime EP1351734B1 (en) | 2001-01-08 | 2001-12-18 | Dry powder inhaler |
Country Status (12)
Country | Link |
---|---|
US (1) | US6626173B2 (en) |
EP (1) | EP1351734B1 (en) |
JP (1) | JP4021323B2 (en) |
AT (1) | ATE378083T1 (en) |
AU (1) | AU2002232674B2 (en) |
CA (1) | CA2433799C (en) |
CY (1) | CY1108525T1 (en) |
DE (1) | DE60131453T2 (en) |
DK (1) | DK1351734T3 (en) |
ES (1) | ES2294044T3 (en) |
PT (1) | PT1351734E (en) |
WO (1) | WO2002053215A2 (en) |
Families Citing this family (79)
Publication number | Priority date | Publication date | Assignee | Title |
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US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
WO2002026223A2 (en) * | 2000-09-29 | 2002-04-04 | Board Of Trustees Operating Michigan State University | Catecholamine pharmaceutical compositions and methods |
US20050147566A1 (en) * | 2002-03-12 | 2005-07-07 | Scott Fleming | Site specific delivery of co-administered drugs via inhalation |
ES2300568T3 (en) | 2002-03-20 | 2008-06-16 | Mannkind Corporation | INHALATION APPARATUS |
US6889690B2 (en) * | 2002-05-10 | 2005-05-10 | Oriel Therapeutics, Inc. | Dry powder inhalers, related blister devices, and associated methods of dispensing dry powder substances and fabricating blister packages |
US8641715B2 (en) | 2002-05-31 | 2014-02-04 | Vidacare Corporation | Manual intraosseous device |
US10973545B2 (en) | 2002-05-31 | 2021-04-13 | Teleflex Life Sciences Limited | Powered drivers, intraosseous devices and methods to access bone marrow |
US11337728B2 (en) | 2002-05-31 | 2022-05-24 | Teleflex Life Sciences Limited | Powered drivers, intraosseous devices and methods to access bone marrow |
CA2485904C (en) | 2002-05-31 | 2013-05-21 | Vidacare Corporation | Apparatus and method to access the bone marrow |
US9072543B2 (en) | 2002-05-31 | 2015-07-07 | Vidacare LLC | Vascular access kits and methods |
US8668698B2 (en) | 2002-05-31 | 2014-03-11 | Vidacare Corporation | Assembly for coupling powered driver with intraosseous device |
US10973532B2 (en) | 2002-05-31 | 2021-04-13 | Teleflex Life Sciences Limited | Powered drivers, intraosseous devices and methods to access bone marrow |
US9504477B2 (en) | 2003-05-30 | 2016-11-29 | Vidacare LLC | Powered driver |
GB0313604D0 (en) * | 2003-06-12 | 2003-07-16 | Britannia Pharmaceuticals Ltd | Delivery device for powdered medicament |
GB0315509D0 (en) | 2003-07-02 | 2003-08-06 | Meridica Ltd | Dispensing device |
WO2005041848A2 (en) * | 2003-10-27 | 2005-05-12 | Oriel Therapeutics, Inc. | Dry powder drug containment system packages with tabs, inhalers and associated methods |
US7861712B2 (en) * | 2004-04-23 | 2011-01-04 | Manta Product Development | Sealed capsule including an integrated puncturing mechanism |
MX2007001903A (en) | 2004-08-20 | 2007-08-02 | Mannkind Corp | Catalysis of diketopiperazine synthesis. |
KR101306384B1 (en) | 2004-08-23 | 2013-09-09 | 맨카인드 코포레이션 | Diketopiperazine salts, diketomorpholine salts or diketodioxane salts for drug delivery |
WO2006037636A2 (en) | 2004-10-06 | 2006-04-13 | Boehringer Ingelheim International Gmbh | Dispensing device, storage device and method for dispensing powder |
JP2006130143A (en) * | 2004-11-08 | 2006-05-25 | Hitachi Ltd | Inhalation administration device and medicine cartridge |
GB0500677D0 (en) * | 2005-01-14 | 2005-02-23 | Britannia Pharmaceuticals Ltd | Dry powder inhaler |
KR101488403B1 (en) | 2005-05-18 | 2015-02-04 | 엠펙스 파마슈티컬즈, 인코포레이티드 | Aerosolized fluoroquinolones and uses thereof |
US8524735B2 (en) | 2005-05-18 | 2013-09-03 | Mpex Pharmaceuticals, Inc. | Aerosolized fluoroquinolones and uses thereof |
JP5465878B2 (en) | 2005-09-14 | 2014-04-09 | マンカインド コーポレイション | Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents |
EP1986722B1 (en) | 2006-01-31 | 2018-10-24 | Oriel Therapeutics, Inc. | Dry powder inhalers having spiral travel paths for microcartridges with dry powder |
CN104383546B (en) | 2006-02-22 | 2021-03-02 | 曼金德公司 | Method for improving the pharmaceutical properties of microparticles comprising diketopiperazines and an active agent |
US8127763B2 (en) * | 2006-03-03 | 2012-03-06 | Stc.Unm | Dry powder inhaler with aeroelastic dispersion mechanism |
JP5188991B2 (en) * | 2006-03-03 | 2013-04-24 | エスティーシー.ユーエヌエム | Dry powder inhaler with aeroelastic distribution mechanism |
CN101489613A (en) * | 2006-07-14 | 2009-07-22 | 阿斯利康(瑞典)有限公司 | Inhalation system and delivery device for the administration of a drug in the form of dry powder |
US8944069B2 (en) | 2006-09-12 | 2015-02-03 | Vidacare Corporation | Assemblies for coupling intraosseous (IO) devices to powered drivers |
DE102006044756A1 (en) * | 2006-09-20 | 2008-04-10 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | inhaler |
WO2008091355A2 (en) * | 2007-01-24 | 2008-07-31 | Breathe Pharmaceuticals, Inc. | Drug transfer device |
US7899528B2 (en) * | 2007-05-17 | 2011-03-01 | Vidacare Corporation | Method and apparatus to monitor patients and treat with intraosseous fluids |
EP2042208A1 (en) * | 2007-09-25 | 2009-04-01 | Boehringer Ingelheim Pharma GmbH & Co. KG | Dispensing device |
US8311914B2 (en) * | 2007-10-30 | 2012-11-13 | Visa U.S.A. Inc. | Payment entity for account payables processing using multiple payment methods |
US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
CN104689432B (en) | 2008-06-13 | 2018-07-06 | 曼金德公司 | Diskus and the system for drug conveying |
JP5479465B2 (en) | 2008-06-20 | 2014-04-23 | マンカインド コーポレイション | Interactive device and method for profiling inhalation efforts in real time |
TWI494123B (en) | 2008-08-11 | 2015-08-01 | Mannkind Corp | Use of ultrarapid acting insulin |
WO2010036839A2 (en) | 2008-09-26 | 2010-04-01 | Oriel Therapeutics, Inc. | Inhalers with airway disks having discrete airway channels and related disks and methods |
CN102159269B (en) | 2008-09-26 | 2014-05-07 | 奥里尔治疗公司 | Dry powder inhalers with dual piercing members and related devices and methods |
ES2550309T3 (en) | 2008-09-26 | 2015-11-06 | Oriel Therapeutics, Inc. | Inhaler mechanisms with radially predisposed perforators and related methods |
WO2010039201A2 (en) | 2008-09-30 | 2010-04-08 | Oriel Therapeutics, Inc. | Dry powder inhalers with multi-facet surface deagglomeration chambers and related devices and methods |
MX2011003245A (en) | 2008-10-01 | 2011-04-26 | Oriel Therapeutics Inc | Dry powder inhalers with rotating piercing mechanisms and related devices and methods. |
US8815838B2 (en) | 2008-10-07 | 2014-08-26 | David C. Griffith | Aerosol fluoroquinolone formulations for improved pharmacokinetics |
PL2346509T3 (en) | 2008-10-07 | 2021-03-08 | Horizon Orphan Llc | Inhalation of levofloxacin for reducing lung inflammation |
US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
PL2405963T3 (en) | 2009-03-11 | 2014-04-30 | Mannkind Corp | Apparatus, system and method for measuring resistance of an inhaler |
EP2440184B1 (en) | 2009-06-12 | 2023-04-05 | MannKind Corporation | Diketopiperazine microparticles with defined specific surface areas |
MX353288B (en) | 2009-09-04 | 2018-01-08 | Raptor Pharmaceuticals Inc | Use of aerosolized levofloxacin for treating cystic fibrosis. |
WO2011056889A1 (en) | 2009-11-03 | 2011-05-12 | Mannkind Corporation | An apparatus and method for simulating inhalation efforts |
US9492625B2 (en) | 2009-11-12 | 2016-11-15 | Stc.Unm | Dry powder inhaler with flutter dispersion member |
AU2010249272C1 (en) * | 2009-12-18 | 2014-07-17 | Bissell Inc. | Dry vacuum cleaner with spot cleaning |
WO2011080761A1 (en) | 2009-12-30 | 2011-07-07 | Thirumalai Anadampillai Aparna | An improved dry powder inhaler |
WO2011085022A1 (en) | 2010-01-05 | 2011-07-14 | Microdose Therapeutx, Inc. | Inhalation device and method |
USD641076S1 (en) | 2010-03-26 | 2011-07-05 | Oriel Therapeutics, Inc. | Dry powder inhaler |
RU2571331C1 (en) | 2010-06-21 | 2015-12-20 | Маннкайнд Корпорейшн | Systems and methods for dry powder drug delivery |
US8561609B2 (en) | 2010-12-07 | 2013-10-22 | Respira Therapeutics, Inc. | Dry powder inhaler |
ES2913095T3 (en) | 2011-01-31 | 2022-05-31 | Avalyn Pharma Inc | Aerosolized pirfenidone and pyridone analog compounds and uses thereof |
DK2694402T3 (en) | 2011-04-01 | 2017-07-03 | Mannkind Corp | BLISTER PACKAGE FOR PHARMACEUTICAL CYLINDER AMPULS |
WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
AU2012328885B2 (en) | 2011-10-24 | 2017-08-31 | Mannkind Corporation | Methods and compositions for treating pain |
US10463815B2 (en) | 2012-02-21 | 2019-11-05 | Respira Therapeutics, Inc. | Inhaler to deliver substances for prophylaxis or prevention of disease or injury caused by the inhalation of biological or chemical agents |
WO2013167429A1 (en) * | 2012-05-09 | 2013-11-14 | Boehringer Ingelheim International Gmbh | Atomizer |
AU2013289957B2 (en) | 2012-07-12 | 2017-02-23 | Mannkind Corporation | Dry powder drug delivery systems and methods |
WO2014066856A1 (en) | 2012-10-26 | 2014-05-01 | Mannkind Corporation | Inhalable influenza vaccine compositions and methods |
EP3587404B1 (en) | 2013-03-15 | 2022-07-13 | MannKind Corporation | Microcrystalline diketopiperazine compositions, methods for preparation and use thereof |
BR112016000937A8 (en) | 2013-07-18 | 2021-06-22 | Mannkind Corp | dry powder pharmaceutical formulations, method for making a dry powder formulation and use of a dry powder pharmaceutical formulation |
CA2919498C (en) | 2013-07-31 | 2023-07-25 | Windward Pharma, Inc. | Aerosol nintedanib compounds and uses thereof |
JP2016530930A (en) | 2013-08-05 | 2016-10-06 | マンカインド コーポレイション | Ventilation device and method |
CN105517610A (en) | 2013-09-04 | 2016-04-20 | 3M创新有限公司 | Dry-powder inhaler and method |
WO2015106150A1 (en) | 2014-01-10 | 2015-07-16 | Genoa Pharmaceuticals Inc. | Aerosol pirfenidone and pyridone analog compounds and uses thereof |
WO2015148905A1 (en) | 2014-03-28 | 2015-10-01 | Mannkind Corporation | Use of ultrarapid acting insulin |
US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
CA2972826C (en) | 2015-01-14 | 2023-09-12 | Respira Therapeutics, Inc. | Powder dispersion methods and devices |
PT3519025T (en) * | 2016-09-30 | 2023-03-03 | De Motu Cordis Pty Ltd | Delivery device and associated methods of use |
WO2022240897A1 (en) | 2021-05-10 | 2022-11-17 | Sepelo Therapeutics, Llc | Pharmaceutical composition comprising delafloxacin for administration into the lung |
WO2023028364A1 (en) | 2021-08-27 | 2023-03-02 | Sepelo Therapeutics, Llc | Targeted compositions and uses therof |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1123827A (en) | 1965-06-19 | 1968-08-14 | Nick Nikodem Urbanowicz | Spray producer |
GB8909891D0 (en) | 1989-04-28 | 1989-06-14 | Riker Laboratories Inc | Device |
IT1237118B (en) | 1989-10-27 | 1993-05-18 | Miat Spa | MULTI-DOSE INHALER FOR POWDER DRUGS. |
AU684754B2 (en) | 1993-03-03 | 1998-01-08 | Glaxo Wellcome Inc. | Dry powder inhalator medicament carrier |
GB9312984D0 (en) | 1993-06-23 | 1993-08-04 | Bespak Plc | Atomising dispenser |
US5388572A (en) | 1993-10-26 | 1995-02-14 | Tenax Corporation (A Connecticut Corp.) | Dry powder medicament inhalator having an inhalation-activated piston to aerosolize dose and deliver same |
FR2718968B1 (en) | 1994-04-20 | 1996-07-26 | Valois Sa | Insert delimiting a metering chamber of an inhaler. |
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US5694920A (en) | 1996-01-25 | 1997-12-09 | Abrams; Andrew L. | Inhalation device |
FR2747311B1 (en) | 1996-04-10 | 1998-08-14 | Pf Medicament | POWDER AND COMPRESSED AIR INHALER |
SE9700422D0 (en) | 1997-02-07 | 1997-02-07 | Astra Ab | Single dose inhaler II |
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US6237590B1 (en) * | 1997-09-18 | 2001-05-29 | Delsys Pharmaceutical Corporation | Dry powder delivery system apparatus |
US6003512A (en) | 1997-11-13 | 1999-12-21 | Lovelace Respiratory Research Institute | Dust gun-aerosol generator and generation |
US6378518B1 (en) * | 1998-10-30 | 2002-04-30 | Richard George Miekka | Method for producing uniform small doses of finely divided substances |
GB9905538D0 (en) | 1999-03-10 | 1999-05-05 | Glaxo Group Ltd | A device |
-
2001
- 2001-01-08 US US09/756,313 patent/US6626173B2/en not_active Expired - Fee Related
- 2001-12-18 DK DK01992208T patent/DK1351734T3/en active
- 2001-12-18 CA CA002433799A patent/CA2433799C/en not_active Expired - Fee Related
- 2001-12-18 JP JP2002554164A patent/JP4021323B2/en not_active Expired - Fee Related
- 2001-12-18 DE DE60131453T patent/DE60131453T2/en not_active Expired - Lifetime
- 2001-12-18 WO PCT/US2001/049409 patent/WO2002053215A2/en active IP Right Grant
- 2001-12-18 AT AT01992208T patent/ATE378083T1/en active
- 2001-12-18 PT PT01992208T patent/PT1351734E/en unknown
- 2001-12-18 EP EP01992208A patent/EP1351734B1/en not_active Expired - Lifetime
- 2001-12-18 ES ES01992208T patent/ES2294044T3/en not_active Expired - Lifetime
- 2001-12-18 AU AU2002232674A patent/AU2002232674B2/en not_active Ceased
-
2008
- 2008-01-15 CY CY20081100056T patent/CY1108525T1/en unknown
Non-Patent Citations (1)
Title |
---|
See references of WO02053215A2 * |
Also Published As
Publication number | Publication date |
---|---|
US20020088462A1 (en) | 2002-07-11 |
WO2002053215A3 (en) | 2003-02-06 |
EP1351734B1 (en) | 2007-11-14 |
JP2004527271A (en) | 2004-09-09 |
DK1351734T3 (en) | 2008-02-11 |
ES2294044T3 (en) | 2008-04-01 |
WO2002053215A2 (en) | 2002-07-11 |
JP4021323B2 (en) | 2007-12-12 |
CY1108525T1 (en) | 2014-04-09 |
DE60131453T2 (en) | 2008-09-04 |
ATE378083T1 (en) | 2007-11-15 |
AU2002232674B2 (en) | 2005-04-28 |
PT1351734E (en) | 2007-12-21 |
US6626173B2 (en) | 2003-09-30 |
CA2433799C (en) | 2008-09-16 |
CA2433799A1 (en) | 2002-07-11 |
DE60131453D1 (en) | 2007-12-27 |
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