WO2002053215A2 - Dry powder inhaler - Google Patents
Dry powder inhaler Download PDFInfo
- Publication number
- WO2002053215A2 WO2002053215A2 PCT/US2001/049409 US0149409W WO02053215A2 WO 2002053215 A2 WO2002053215 A2 WO 2002053215A2 US 0149409 W US0149409 W US 0149409W WO 02053215 A2 WO02053215 A2 WO 02053215A2
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- dose
- sheet
- pressurized air
- substrate
- trough
- Prior art date
Links
- 229940112141 dry powder inhaler Drugs 0.000 title claims abstract description 8
- 239000000843 powder Substances 0.000 claims abstract description 46
- 239000002245 particle Substances 0.000 claims abstract description 13
- 239000000758 substrate Substances 0.000 claims description 59
- 239000003814 drug Substances 0.000 claims description 11
- 239000000463 material Substances 0.000 claims description 9
- 238000000034 method Methods 0.000 claims description 6
- 230000004913 activation Effects 0.000 claims description 5
- 229920002799 BoPET Polymers 0.000 claims description 3
- 239000005041 Mylar™ Substances 0.000 claims description 3
- 230000001681 protective effect Effects 0.000 claims description 2
- 238000007664 blowing Methods 0.000 claims 1
- 239000007787 solid Substances 0.000 description 4
- 229940079593 drug Drugs 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- -1 polypropylene Polymers 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- 239000004698 Polyethylene Substances 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 229920000122 acrylonitrile butadiene styrene Polymers 0.000 description 1
- 239000004676 acrylonitrile butadiene styrene Substances 0.000 description 1
- 239000000443 aerosol Substances 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 230000002939 deleterious effect Effects 0.000 description 1
- 238000012377 drug delivery Methods 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- 239000010419 fine particle Substances 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 239000008188 pellet Substances 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 238000009877 rendering Methods 0.000 description 1
- 230000000241 respiratory effect Effects 0.000 description 1
- 230000000153 supplemental effect Effects 0.000 description 1
- 230000001960 triggered effect Effects 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B17/00—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
- B05B17/04—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
- B05B17/06—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
- B05B17/0692—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by a fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/001—Particle size control
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/005—Sprayers or atomisers specially adapted for therapeutic purposes using ultrasonics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/02—Sprayers or atomisers specially adapted for therapeutic purposes operated by air or other gas pressure applied to the liquid or other product to be sprayed or atomised
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0005—Details of inhalators; Constructional features thereof with means for agitating the medicament
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
- A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
- A61M15/0048—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged in a plane, e.g. on diskettes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Filling Or Emptying Of Bunkers, Hoppers, And Tanks (AREA)
Abstract
Description
Claims
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2002554164A JP4021323B2 (en) | 2001-01-08 | 2001-12-18 | Dry powder inhaler |
CA002433799A CA2433799C (en) | 2001-01-08 | 2001-12-18 | Dry powder inhaler |
AU2002232674A AU2002232674B2 (en) | 2001-01-08 | 2001-12-18 | Dry powder inhaler |
DK01992208T DK1351734T3 (en) | 2001-01-08 | 2001-12-18 | Dry powder inhaler |
DE60131453T DE60131453T2 (en) | 2001-01-08 | 2001-12-18 | dry powder inhaler |
EP01992208A EP1351734B1 (en) | 2001-01-08 | 2001-12-18 | Dry powder inhaler |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/756,313 | 2001-01-08 | ||
US09/756,313 US6626173B2 (en) | 2001-01-08 | 2001-01-08 | Dry powder inhaler |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2002053215A2 true WO2002053215A2 (en) | 2002-07-11 |
WO2002053215A3 WO2002053215A3 (en) | 2003-02-06 |
Family
ID=25042937
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2001/049409 WO2002053215A2 (en) | 2001-01-08 | 2001-12-18 | Dry powder inhaler |
Country Status (12)
Country | Link |
---|---|
US (1) | US6626173B2 (en) |
EP (1) | EP1351734B1 (en) |
JP (1) | JP4021323B2 (en) |
AT (1) | ATE378083T1 (en) |
AU (1) | AU2002232674B2 (en) |
CA (1) | CA2433799C (en) |
CY (1) | CY1108525T1 (en) |
DE (1) | DE60131453T2 (en) |
DK (1) | DK1351734T3 (en) |
ES (1) | ES2294044T3 (en) |
PT (1) | PT1351734E (en) |
WO (1) | WO2002053215A2 (en) |
Cited By (11)
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---|---|---|---|---|
EP1644063A2 (en) | 2003-07-02 | 2006-04-12 | Pfizer Limited | Dispensing device |
WO2006037636A2 (en) * | 2004-10-06 | 2006-04-13 | Boehringer Ingelheim International Gmbh | Dispensing device, storage device and method for dispensing powder |
WO2008034504A2 (en) * | 2006-09-20 | 2008-03-27 | Boehringer Ingelheim International Gmbh | Inhaler |
WO2010036839A2 (en) * | 2008-09-26 | 2010-04-01 | Oriel Therapeutics, Inc. | Inhalers with airway disks having discrete airway channels and related disks and methods |
CN102100504A (en) * | 2009-12-18 | 2011-06-22 | 碧洁家庭护理有限公司 | Dry vacuum cleaner with spot cleaning function and method for cleaning surface to be cleaned |
WO2011080761A1 (en) | 2009-12-30 | 2011-07-07 | Thirumalai Anadampillai Aparna | An improved dry powder inhaler |
US8381721B2 (en) | 2008-09-26 | 2013-02-26 | Oriel Therapeutics, Inc. | Dry powder inhalers with dual piercing members and related devices and methods |
US8646446B2 (en) | 2008-10-01 | 2014-02-11 | Oriel Therapeutics, Inc. | Dry powder inhalers with rotating piercing mechanisms and related devices and methods |
US8887722B2 (en) | 2008-09-26 | 2014-11-18 | Oriel Therapeutics, Inc. | Inhaler mechanisms with radially biased piercers and related methods |
US9050427B2 (en) | 2008-09-30 | 2015-06-09 | Oriel Therapeutics, Inc. | Dry powder inhalers with multi-facet surface deagglomeration chambers and related devices and methods |
EP3519025A4 (en) * | 2016-09-30 | 2020-08-26 | De Motu Cordis Pty Ltd | Delivery device and associated methods of use |
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US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
JP2004509920A (en) * | 2000-09-29 | 2004-04-02 | ボード オブ トラスティーズ オペレーティング ミシガン ステート ユニヴァーシティ | Catecholamine pharmaceutical compositions and methods |
EP1487407A4 (en) * | 2002-03-12 | 2010-08-25 | Microdose Therapeutx Inc | Site specific delivery of co-administered drugs via inhalation |
ES2425392T3 (en) | 2002-03-20 | 2013-10-15 | Mannkind Corporation | Cartridge for an inhalation device |
US6889690B2 (en) * | 2002-05-10 | 2005-05-10 | Oriel Therapeutics, Inc. | Dry powder inhalers, related blister devices, and associated methods of dispensing dry powder substances and fabricating blister packages |
US11337728B2 (en) | 2002-05-31 | 2022-05-24 | Teleflex Life Sciences Limited | Powered drivers, intraosseous devices and methods to access bone marrow |
CA2898210C (en) | 2002-05-31 | 2018-11-13 | Vidacare Corporation | Apparatus and method to access bone marrow |
US8668698B2 (en) | 2002-05-31 | 2014-03-11 | Vidacare Corporation | Assembly for coupling powered driver with intraosseous device |
US10973545B2 (en) | 2002-05-31 | 2021-04-13 | Teleflex Life Sciences Limited | Powered drivers, intraosseous devices and methods to access bone marrow |
US10973532B2 (en) | 2002-05-31 | 2021-04-13 | Teleflex Life Sciences Limited | Powered drivers, intraosseous devices and methods to access bone marrow |
US8641715B2 (en) | 2002-05-31 | 2014-02-04 | Vidacare Corporation | Manual intraosseous device |
US9072543B2 (en) | 2002-05-31 | 2015-07-07 | Vidacare LLC | Vascular access kits and methods |
US9504477B2 (en) | 2003-05-30 | 2016-11-29 | Vidacare LLC | Powered driver |
GB0313604D0 (en) * | 2003-06-12 | 2003-07-16 | Britannia Pharmaceuticals Ltd | Delivery device for powdered medicament |
WO2005041848A2 (en) * | 2003-10-27 | 2005-05-12 | Oriel Therapeutics, Inc. | Dry powder drug containment system packages with tabs, inhalers and associated methods |
US7861712B2 (en) * | 2004-04-23 | 2011-01-04 | Manta Product Development | Sealed capsule including an integrated puncturing mechanism |
ATE486064T1 (en) | 2004-08-20 | 2010-11-15 | Mannkind Corp | CATALYSIS OF DIKETOPIPERAZINE SYNTHESIS |
PL1791542T3 (en) | 2004-08-23 | 2015-11-30 | Mannkind Corp | Diketopiperazine salts for drug delivery |
JP2006130143A (en) * | 2004-11-08 | 2006-05-25 | Hitachi Ltd | Inhalation administration device and medicine cartridge |
GB0500677D0 (en) * | 2005-01-14 | 2005-02-23 | Britannia Pharmaceuticals Ltd | Dry powder inhaler |
US8524734B2 (en) | 2005-05-18 | 2013-09-03 | Mpex Pharmaceuticals, Inc. | Aerosolized fluoroquinolones and uses thereof |
DK1901749T3 (en) | 2005-05-18 | 2016-10-24 | Raptor Pharmaceuticals Inc | Aerosolized fluoroquinolones AND USES THEREOF |
AU2006290870B2 (en) | 2005-09-14 | 2013-02-28 | Mannkind Corporation | Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces |
US7987845B2 (en) * | 2006-01-31 | 2011-08-02 | Oriel Therapeutics, Inc. | Dry powder inhalers having spiral travel paths, unit dose microcartridges with dry powder, related devices and methods |
EP2497484A3 (en) | 2006-02-22 | 2012-11-07 | MannKind Corporation | A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent |
CN101437562A (en) * | 2006-03-03 | 2009-05-20 | Stc.Unm公司 | Dry powder inhaler with aeroelastic dispersion mechanism |
US8127763B2 (en) * | 2006-03-03 | 2012-03-06 | Stc.Unm | Dry powder inhaler with aeroelastic dispersion mechanism |
US20090250058A1 (en) * | 2006-07-14 | 2009-10-08 | Astrazeneca Ab | Inhalation System and Delivery Device for the Administration of a Drug in the Form of Dry Powder |
US8944069B2 (en) | 2006-09-12 | 2015-02-03 | Vidacare Corporation | Assemblies for coupling intraosseous (IO) devices to powered drivers |
WO2008091355A2 (en) * | 2007-01-24 | 2008-07-31 | Breathe Pharmaceuticals, Inc. | Drug transfer device |
CN101720243A (en) * | 2007-05-17 | 2010-06-02 | 维达保健公司 | Monitor patients and with the method and apparatus of treat with intraosseous fluids |
EP2042208A1 (en) * | 2007-09-25 | 2009-04-01 | Boehringer Ingelheim Pharma GmbH & Co. KG | Dispensing device |
US8311914B2 (en) * | 2007-10-30 | 2012-11-13 | Visa U.S.A. Inc. | Payment entity for account payables processing using multiple payment methods |
US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
DK2570147T3 (en) | 2008-06-13 | 2018-01-29 | Mannkind Corp | DRY POWDER INHALATOR AND MEDICINAL ADMINISTRATION SYSTEM |
KR101628410B1 (en) | 2008-06-20 | 2016-06-08 | 맨카인드 코포레이션 | An interactive apparatus and method for real-time profiling of inhalation efforts |
TWI532497B (en) | 2008-08-11 | 2016-05-11 | 曼凱公司 | Use of ultrarapid acting insulin |
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CA2739893C (en) | 2008-10-07 | 2016-10-04 | Mpex Pharmaceuticals, Inc. | Inhalation of levofloxacin for reducing lung inflammation |
US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
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RU2015130524A (en) | 2009-09-04 | 2018-12-21 | Раптор Фармасьютикалз Инк. | The use of levofloxacin in the form of an aerosol for the treatment of cystic fibrosis |
CA2778698A1 (en) | 2009-11-03 | 2011-05-12 | Mannkind Corporation | An apparatus and method for simulating inhalation efforts |
WO2011060334A2 (en) | 2009-11-12 | 2011-05-19 | Stc.Unm | Dry powder inhaler with flutter dispersion member |
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US8561609B2 (en) | 2010-12-07 | 2013-10-22 | Respira Therapeutics, Inc. | Dry powder inhaler |
US10092552B2 (en) | 2011-01-31 | 2018-10-09 | Avalyn Pharma Inc. | Aerosol pirfenidone and pyridone analog compounds and uses thereof |
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US10463815B2 (en) | 2012-02-21 | 2019-11-05 | Respira Therapeutics, Inc. | Inhaler to deliver substances for prophylaxis or prevention of disease or injury caused by the inhalation of biological or chemical agents |
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CA2878457C (en) | 2012-07-12 | 2021-01-19 | Mannkind Corporation | Dry powder drug delivery systems and methods |
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CN114848614A (en) | 2013-07-18 | 2022-08-05 | 曼金德公司 | Heat stable dry powder pharmaceutical compositions and methods |
WO2015017728A1 (en) | 2013-07-31 | 2015-02-05 | Windward Pharma, Inc. | Aerosol tyrosine kinase inhibitor compounds and uses thereof |
CA2920488C (en) | 2013-08-05 | 2022-04-26 | Mannkind Corporation | Insufflation apparatus and methods |
WO2015034709A1 (en) | 2013-09-04 | 2015-03-12 | 3M Innovative Properties Company | Dry-powder inhaler and method |
NZ722927A (en) | 2014-01-10 | 2022-07-29 | Avalyn Pharma Inc | Aerosol pirfenidone and pyridone analog compounds and uses thereof |
US10307464B2 (en) | 2014-03-28 | 2019-06-04 | Mannkind Corporation | Use of ultrarapid acting insulin |
US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
JP2018501903A (en) | 2015-01-14 | 2018-01-25 | レスピラ セラピューティクス インコーポレイテッドRespira Therapeutics,Inc. | Powder dispersion method and apparatus |
WO2022240897A1 (en) | 2021-05-10 | 2022-11-17 | Sepelo Therapeutics, Llc | Pharmaceutical composition comprising delafloxacin for administration into the lung |
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Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1123827A (en) * | 1965-06-19 | 1968-08-14 | Nick Nikodem Urbanowicz | Spray producer |
US5653227A (en) * | 1993-06-23 | 1997-08-05 | Bespak Plc | Atomizing dispenser |
US5724960A (en) * | 1994-04-20 | 1998-03-10 | Valois S.A. | Insert defining a measuring chamber of an inhaler device |
US5740793A (en) * | 1989-04-28 | 1998-04-21 | Astra Aktiebolag | Dry powder inhalation device with elongate carrier for power |
WO1998034662A1 (en) * | 1997-02-07 | 1998-08-13 | Astra Aktiebolag (Publ) | Single dose inhaler ii |
WO2000053248A1 (en) * | 1999-03-10 | 2000-09-14 | Glaxo Group Limited | Improvements relating to an inhalation device |
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IT1237118B (en) | 1989-10-27 | 1993-05-18 | Miat Spa | MULTI-DOSE INHALER FOR POWDER DRUGS. |
KR960701672A (en) | 1993-03-03 | 1996-03-28 | 윌리엄 피. 알트만 | DRY POWDER INHALATOR MEDICAMENT CARRIER |
US5388572A (en) | 1993-10-26 | 1995-02-14 | Tenax Corporation (A Connecticut Corp.) | Dry powder medicament inhalator having an inhalation-activated piston to aerosolize dose and deliver same |
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FR2747311B1 (en) | 1996-04-10 | 1998-08-14 | Pf Medicament | POWDER AND COMPRESSED AIR INHALER |
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US6378518B1 (en) * | 1998-10-30 | 2002-04-30 | Richard George Miekka | Method for producing uniform small doses of finely divided substances |
-
2001
- 2001-01-08 US US09/756,313 patent/US6626173B2/en not_active Expired - Fee Related
- 2001-12-18 JP JP2002554164A patent/JP4021323B2/en not_active Expired - Fee Related
- 2001-12-18 ES ES01992208T patent/ES2294044T3/en not_active Expired - Lifetime
- 2001-12-18 DE DE60131453T patent/DE60131453T2/en not_active Expired - Lifetime
- 2001-12-18 CA CA002433799A patent/CA2433799C/en not_active Expired - Fee Related
- 2001-12-18 EP EP01992208A patent/EP1351734B1/en not_active Expired - Lifetime
- 2001-12-18 WO PCT/US2001/049409 patent/WO2002053215A2/en active IP Right Grant
- 2001-12-18 AU AU2002232674A patent/AU2002232674B2/en not_active Ceased
- 2001-12-18 PT PT01992208T patent/PT1351734E/en unknown
- 2001-12-18 DK DK01992208T patent/DK1351734T3/en active
- 2001-12-18 AT AT01992208T patent/ATE378083T1/en active
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2008
- 2008-01-15 CY CY20081100056T patent/CY1108525T1/en unknown
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US8181645B2 (en) | 2003-07-02 | 2012-05-22 | Pfizer Ltd. | Dispensing device |
US11116917B2 (en) | 2003-07-02 | 2021-09-14 | Pfizer Limited | Dispensing device |
US10124130B2 (en) | 2003-07-02 | 2018-11-13 | Pfizer Limited | Dispensing device |
EP1644063B1 (en) * | 2003-07-02 | 2017-12-27 | Pfizer Limited | Dispensing device |
US9399103B2 (en) | 2003-07-02 | 2016-07-26 | Pfizer Limited | Dispensing device |
KR100900122B1 (en) * | 2003-07-02 | 2009-06-01 | 화이자 리미티드 | Dispensing device |
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US8851070B2 (en) | 2003-07-02 | 2014-10-07 | Pfizer Limited | Dispensing device |
US9283335B2 (en) | 2004-10-06 | 2016-03-15 | Boehringer Ingelheim International Gmbh | Dispensing device, storage device and method for dispensing powder |
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US8887722B2 (en) | 2008-09-26 | 2014-11-18 | Oriel Therapeutics, Inc. | Inhaler mechanisms with radially biased piercers and related methods |
US8985103B2 (en) | 2008-09-26 | 2015-03-24 | Oriel Therapeutics, Inc. | Dry powder inhalers with dual piercing members |
US8381721B2 (en) | 2008-09-26 | 2013-02-26 | Oriel Therapeutics, Inc. | Dry powder inhalers with dual piercing members and related devices and methods |
US8550071B2 (en) | 2008-09-26 | 2013-10-08 | Oriel Therapeutics, Inc. | Inhalers with airway disks having discrete airway channels and related disks and methods |
WO2010036839A2 (en) * | 2008-09-26 | 2010-04-01 | Oriel Therapeutics, Inc. | Inhalers with airway disks having discrete airway channels and related disks and methods |
AU2009296538B2 (en) * | 2008-09-26 | 2013-06-13 | Oriel Therapeutics, Inc. | Inhalers with airway disks having discrete airway channels and related disks and methods |
US9795749B2 (en) | 2008-09-26 | 2017-10-24 | Oriel Therapeutics, Inc. | Dry powder inhalers with dual piercing members and methods of operating same |
US9050427B2 (en) | 2008-09-30 | 2015-06-09 | Oriel Therapeutics, Inc. | Dry powder inhalers with multi-facet surface deagglomeration chambers and related devices and methods |
US8646446B2 (en) | 2008-10-01 | 2014-02-11 | Oriel Therapeutics, Inc. | Dry powder inhalers with rotating piercing mechanisms and related devices and methods |
CN102100504A (en) * | 2009-12-18 | 2011-06-22 | 碧洁家庭护理有限公司 | Dry vacuum cleaner with spot cleaning function and method for cleaning surface to be cleaned |
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Also Published As
Publication number | Publication date |
---|---|
CY1108525T1 (en) | 2014-04-09 |
EP1351734A2 (en) | 2003-10-15 |
DE60131453T2 (en) | 2008-09-04 |
CA2433799A1 (en) | 2002-07-11 |
ES2294044T3 (en) | 2008-04-01 |
DK1351734T3 (en) | 2008-02-11 |
EP1351734B1 (en) | 2007-11-14 |
ATE378083T1 (en) | 2007-11-15 |
CA2433799C (en) | 2008-09-16 |
JP4021323B2 (en) | 2007-12-12 |
WO2002053215A3 (en) | 2003-02-06 |
AU2002232674B2 (en) | 2005-04-28 |
JP2004527271A (en) | 2004-09-09 |
US20020088462A1 (en) | 2002-07-11 |
PT1351734E (en) | 2007-12-21 |
DE60131453D1 (en) | 2007-12-27 |
US6626173B2 (en) | 2003-09-30 |
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