EP1341762A1 - Verfahren zur racematspaltung von piperidinderivaten - Google Patents

Verfahren zur racematspaltung von piperidinderivaten

Info

Publication number
EP1341762A1
EP1341762A1 EP01273837A EP01273837A EP1341762A1 EP 1341762 A1 EP1341762 A1 EP 1341762A1 EP 01273837 A EP01273837 A EP 01273837A EP 01273837 A EP01273837 A EP 01273837A EP 1341762 A1 EP1341762 A1 EP 1341762A1
Authority
EP
European Patent Office
Prior art keywords
enantiomer
mixture
benzoyl
acid
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP01273837A
Other languages
English (en)
French (fr)
Inventor
Eric David Moher
Allie Edward Tripp
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of EP1341762A1 publication Critical patent/EP1341762A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
EP01273837A 2000-11-20 2001-11-13 Verfahren zur racematspaltung von piperidinderivaten Withdrawn EP1341762A1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24997100P 2000-11-20 2000-11-20
US249971P 2000-11-20
PCT/US2001/042934 WO2002068391A1 (en) 2000-11-20 2001-11-13 Process for resolving racemic mixtures of piperidine derivatives

Publications (1)

Publication Number Publication Date
EP1341762A1 true EP1341762A1 (de) 2003-09-10

Family

ID=22945777

Family Applications (1)

Application Number Title Priority Date Filing Date
EP01273837A Withdrawn EP1341762A1 (de) 2000-11-20 2001-11-13 Verfahren zur racematspaltung von piperidinderivaten

Country Status (3)

Country Link
EP (1) EP1341762A1 (de)
AU (1) AU2001297647A1 (de)
WO (1) WO2002068391A1 (de)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014128139A1 (en) 2013-02-20 2014-08-28 Reuter Chemische Apparatebau Kg Process for the preparation of enantiomerically enriched 3-aminopiperidine
WO2014173855A1 (en) 2013-04-22 2014-10-30 Reuter Chemische Apparatebau Kg Process for preparing enantiomerically enriched 3-hydroxymethylpiperidine

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000071519A2 (en) * 1999-05-21 2000-11-30 Eli Lilly And Company Immunopotentiator agents
SE0303220D0 (sv) 2003-11-28 2003-11-28 Astrazeneca Ab New process
CN109761886B (zh) * 2019-02-21 2020-09-11 北京悦康科创医药科技股份有限公司 一种阿加曲班起始原料异构体杂质的拆分方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000071519A2 (en) * 1999-05-21 2000-11-30 Eli Lilly And Company Immunopotentiator agents

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO02068391A1 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014128139A1 (en) 2013-02-20 2014-08-28 Reuter Chemische Apparatebau Kg Process for the preparation of enantiomerically enriched 3-aminopiperidine
EP3653607A2 (de) 2013-02-20 2020-05-20 Reuter Chemische Apparatenbau e.K. Verfahren zur herstellung von enantiomer angereichertem 3-aminoperidin
EP4289819A2 (de) 2013-02-20 2023-12-13 Reuter Chemische Apparatebau e.K. Verfahren zur herstellung von enantiomer angereichertem 3-aminopiperidin
WO2014173855A1 (en) 2013-04-22 2014-10-30 Reuter Chemische Apparatebau Kg Process for preparing enantiomerically enriched 3-hydroxymethylpiperidine

Also Published As

Publication number Publication date
AU2001297647A1 (en) 2002-09-12
WO2002068391A1 (en) 2002-09-06
WO2002068391A8 (en) 2003-12-11

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