EP1307211A4 - Immunmediatoren und verwandte methoden - Google Patents

Immunmediatoren und verwandte methoden

Info

Publication number
EP1307211A4
EP1307211A4 EP01934857A EP01934857A EP1307211A4 EP 1307211 A4 EP1307211 A4 EP 1307211A4 EP 01934857 A EP01934857 A EP 01934857A EP 01934857 A EP01934857 A EP 01934857A EP 1307211 A4 EP1307211 A4 EP 1307211A4
Authority
EP
European Patent Office
Prior art keywords
related methods
immune mediators
mediators
immune
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP01934857A
Other languages
English (en)
French (fr)
Other versions
EP1307211A1 (de
Inventor
Darrick Carter
Shirley Zhu
Subhashini Arimilli
Aijun Wang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Corixa Corp
Original Assignee
Corixa Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Corixa Corp filed Critical Corixa Corp
Publication of EP1307211A1 publication Critical patent/EP1307211A1/de
Publication of EP1307211A4 publication Critical patent/EP1307211A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70539—MHC-molecules, e.g. HLA-molecules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/605—MHC molecules or ligands thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rheumatology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
EP01934857A 2000-03-22 2001-03-22 Immunmediatoren und verwandte methoden Withdrawn EP1307211A4 (de)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US19127400P 2000-03-22 2000-03-22
US191274P 2000-03-22
US20424900P 2000-05-15 2000-05-15
US204249P 2000-05-15
US26400301P 2001-01-23 2001-01-23
US264003P 2001-01-23
PCT/US2001/009616 WO2001070245A1 (en) 2000-03-22 2001-03-22 Immune mediators and related methods

Publications (2)

Publication Number Publication Date
EP1307211A1 EP1307211A1 (de) 2003-05-07
EP1307211A4 true EP1307211A4 (de) 2005-01-05

Family

ID=27392878

Family Applications (1)

Application Number Title Priority Date Filing Date
EP01934857A Withdrawn EP1307211A4 (de) 2000-03-22 2001-03-22 Immunmediatoren und verwandte methoden

Country Status (4)

Country Link
EP (1) EP1307211A4 (de)
AU (1) AU2001261005A1 (de)
CA (1) CA2403432A1 (de)
WO (1) WO2001070245A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001094418A2 (en) * 2000-06-05 2001-12-13 Corixa Corporation Leader peptides for enhancing secretion of recombinant protein from a host cell
EP1749889A1 (de) * 2000-06-05 2007-02-07 Corixa Corporation Leader-Anteile zur Erhöhung der Sekretion von rekombinanten Proteinen aus einer Wirtzelle
NZ533587A (en) * 2001-11-16 2005-11-25 Pharmexa As Immunogenic mimetics of multimer proteins with promiscuous T cell epitope inserts
US8314210B2 (en) 2002-07-12 2012-11-20 Dana-Farber Cancer Institute, Inc. Compositions and methods for the generation of MHC class II compounds by peptide exchange
US20050287631A1 (en) * 2003-11-25 2005-12-29 Martin Kroenke Compositions and methods related to a dimeric MHC class I and II-Like molecule (dsMHCI and dsMHCII)
US7576183B2 (en) * 2003-12-24 2009-08-18 Los Alamos National Security, Llc Structure-based receptor MIMICS targeted against bacterial superantigen toxins
WO2008116468A2 (en) 2007-03-26 2008-10-02 Dako Denmark A/S Mhc peptide complexes and uses thereof in infectious diseases
EP2167537A2 (de) 2007-07-03 2010-03-31 Dako Denmark A/S Zusammengestellte verfahren für die analyse und sortierung von proben
EP2197908A2 (de) 2007-09-27 2010-06-23 Dako Denmark A/S Mhc-multimere in tuberkulose-diagnostika, -impfstoff und therapeutika
US10968269B1 (en) 2008-02-28 2021-04-06 Agilent Technologies, Inc. MHC multimers in borrelia diagnostics and disease
US10722562B2 (en) 2008-07-23 2020-07-28 Immudex Aps Combinatorial analysis and repair
GB0817244D0 (en) 2008-09-20 2008-10-29 Univ Cardiff Use of a protein kinase inhibitor to detect immune cells, such as T cells
WO2010037402A1 (en) 2008-10-02 2010-04-08 Dako Denmark A/S Molecular vaccines for infectious disease
US11992518B2 (en) 2008-10-02 2024-05-28 Agilent Technologies, Inc. Molecular vaccines for infectious disease

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999009064A1 (en) * 1997-08-19 1999-02-25 Mount Sinai School Of Medicine Of New York University ; Epitope-bearing major histocompatibility complex class ii element/immunoglobulin chimeric molecules
WO1999013095A2 (en) * 1997-09-11 1999-03-18 The Johns Hopkins University School Of Medicine Use of multivalent chimeric peptide-loaded, mhc/ig molecules to detect, activate or suppress antigen-specific t cell-dependent immune responses
WO1999014236A1 (en) * 1997-09-16 1999-03-25 Oregon Health Sciences University Recombinant mhc molecules useful for manipulation of antigen-specific t-cells

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5194425A (en) * 1988-06-23 1993-03-16 Anergen, Inc. Mhc-mediated toxic conjugates useful in ameliorating autoimmunity
US6015884A (en) * 1996-03-28 2000-01-18 The Johns Hopkins University Soluble divalent and multivalent heterodimeric analogs of proteins

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999009064A1 (en) * 1997-08-19 1999-02-25 Mount Sinai School Of Medicine Of New York University ; Epitope-bearing major histocompatibility complex class ii element/immunoglobulin chimeric molecules
WO1999013095A2 (en) * 1997-09-11 1999-03-18 The Johns Hopkins University School Of Medicine Use of multivalent chimeric peptide-loaded, mhc/ig molecules to detect, activate or suppress antigen-specific t cell-dependent immune responses
WO1999014236A1 (en) * 1997-09-16 1999-03-25 Oregon Health Sciences University Recombinant mhc molecules useful for manipulation of antigen-specific t-cells

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BURROWS G G ET AL: "Two-domain MHC class II molecules form stable complexes with myelin basic protein 69-89 peptide that detect and inhibit rat encephalitogenic T cells and treat experimental autoimmune encephalomyelitis", JOURNAL OF IMMUNOLOGY, THE WILLIAMS AND WILKINS CO. BALTIMORE, US, vol. 161, 1998, pages 5987 - 5996, XP002216664, ISSN: 0022-1767 *
CASARES ET AL: "ENGINEERING AND CHARACTERIZATION OF A MURINE MHC CLASS II-IMMUNOGLOBULIN CHIMERA EXPRESSING AN IMMUNODOMINANT CD4 T VIRAL EPITOPE", PROTEIN ENGINEERING, OXFORD UNIVERSITY PRESS, SURREY, GB, vol. 10, no. 11, 1997, pages 1295 - 1301, XP002097124, ISSN: 0269-2139 *
GREER J M ET AL: "Immunogenic and encephalitogenic epitope clusters of myelin proteolipid protein.", JOURNAL OF IMMUNOLOGY (BALTIMORE, MD. : 1950) 1 JAN 1996, vol. 156, no. 1, 1 January 1996 (1996-01-01), pages 371 - 379, XP002304260, ISSN: 0022-1767 *
RHODE P R ET AL: "SINGLE-CHAIN MHC CLASS II MOLECULES INDUCE T CELL ACTIVATION AND APOPTOSIS", JOURNAL OF IMMUNOLOGY, THE WILLIAMS AND WILKINS CO. BALTIMORE, US, vol. 157, no. 11, 1996, pages 4885 - 4891, XP000652225, ISSN: 0022-1767 *
See also references of WO0170245A1 *

Also Published As

Publication number Publication date
WO2001070245A1 (en) 2001-09-27
EP1307211A1 (de) 2003-05-07
AU2001261005A1 (en) 2001-10-03
CA2403432A1 (en) 2001-09-27
WO2001070245A9 (en) 2002-12-19

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20021001

AK Designated contracting states

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

AX Request for extension of the european patent

Extension state: AL LT LV MK RO SI

RIN1 Information on inventor provided before grant (corrected)

Inventor name: WANG, AIJUN

Inventor name: ARIMILLI, SUBHASHINI

Inventor name: ZHU, SHIRLEY

Inventor name: CARTER, DARRICK

RIC1 Information provided on ipc code assigned before grant

Ipc: 7C 07K 14/705 B

Ipc: 7A 61K 35/28 A

A4 Supplementary search report drawn up and despatched

Effective date: 20041118

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20050204