EP1192009A4 - Method for producing an aerosol - Google Patents

Method for producing an aerosol

Info

Publication number
EP1192009A4
EP1192009A4 EP00938249A EP00938249A EP1192009A4 EP 1192009 A4 EP1192009 A4 EP 1192009A4 EP 00938249 A EP00938249 A EP 00938249A EP 00938249 A EP00938249 A EP 00938249A EP 1192009 A4 EP1192009 A4 EP 1192009A4
Authority
EP
European Patent Office
Prior art keywords
aerosol
producing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP00938249A
Other languages
German (de)
French (fr)
Other versions
EP1192009A1 (en
EP1192009B1 (en
Inventor
Joan Rosell
Alfonso Ganan-Calvo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universidad de Sevilla
Aradigm Corp
Original Assignee
Universidad de Sevilla
Aradigm Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universidad de Sevilla, Aradigm Corp filed Critical Universidad de Sevilla
Publication of EP1192009A1 publication Critical patent/EP1192009A1/en
Publication of EP1192009A4 publication Critical patent/EP1192009A4/en
Application granted granted Critical
Publication of EP1192009B1 publication Critical patent/EP1192009B1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B7/00—Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
    • B05B7/02—Spray pistols; Apparatus for discharge
    • B05B7/04—Spray pistols; Apparatus for discharge with arrangements for mixing liquids or other fluent materials before discharge
    • B05B7/0416—Spray pistols; Apparatus for discharge with arrangements for mixing liquids or other fluent materials before discharge with arrangements for mixing one gas and one liquid
    • B05B7/0441—Spray pistols; Apparatus for discharge with arrangements for mixing liquids or other fluent materials before discharge with arrangements for mixing one gas and one liquid with one inner conduit of liquid surrounded by an external conduit of gas upstream the mixing chamber
    • B05B7/0475—Spray pistols; Apparatus for discharge with arrangements for mixing liquids or other fluent materials before discharge with arrangements for mixing one gas and one liquid with one inner conduit of liquid surrounded by an external conduit of gas upstream the mixing chamber with means for deflecting the peripheral gas flow towards the central liquid flow
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B7/00—Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
    • B05B7/02—Spray pistols; Apparatus for discharge
    • B05B7/04—Spray pistols; Apparatus for discharge with arrangements for mixing liquids or other fluent materials before discharge
    • B05B7/0416—Spray pistols; Apparatus for discharge with arrangements for mixing liquids or other fluent materials before discharge with arrangements for mixing one gas and one liquid
    • B05B7/0483—Spray pistols; Apparatus for discharge with arrangements for mixing liquids or other fluent materials before discharge with arrangements for mixing one gas and one liquid with gas and liquid jets intersecting in the mixing chamber
EP00938249.0A 1999-06-11 2000-06-09 Method for producing an aerosol Expired - Lifetime EP1192009B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13869899P 1999-06-11 1999-06-11
US138698P 1999-06-11
PCT/US2000/015931 WO2000076673A1 (en) 1999-06-11 2000-06-09 Method for producing an aerosol

Publications (3)

Publication Number Publication Date
EP1192009A1 EP1192009A1 (en) 2002-04-03
EP1192009A4 true EP1192009A4 (en) 2006-10-18
EP1192009B1 EP1192009B1 (en) 2013-05-01

Family

ID=22483216

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00938249.0A Expired - Lifetime EP1192009B1 (en) 1999-06-11 2000-06-09 Method for producing an aerosol

Country Status (6)

Country Link
EP (1) EP1192009B1 (en)
JP (1) JP2003501257A (en)
AU (1) AU767486B2 (en)
CA (1) CA2374232C (en)
ES (1) ES2424713T4 (en)
WO (1) WO2000076673A1 (en)

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US6805853B2 (en) 2001-11-09 2004-10-19 Alexza Molecular Delivery Corporation Delivery of diazepam through an inhalation route
US7766013B2 (en) 2001-06-05 2010-08-03 Alexza Pharmaceuticals, Inc. Aerosol generating method and device
US6759029B2 (en) 2001-05-24 2004-07-06 Alexza Molecular Delivery Corporation Delivery of rizatriptan and zolmitriptan through an inhalation route
US6737043B2 (en) 2001-05-24 2004-05-18 Alexza Molecula Delivery Corporation Delivery of alprazolam, estazolam, midazolam or triazolam through an inhalation route
US7078016B2 (en) 2001-11-21 2006-07-18 Alexza Pharmaceuticals, Inc. Delivery of caffeine through an inhalation route
US6737042B2 (en) 2001-05-24 2004-05-18 Alexza Molecular Delivery Corporation Delivery of drug esters through an inhalation route
US20070122353A1 (en) 2001-05-24 2007-05-31 Hale Ron L Drug condensation aerosols and kits
JP4834861B2 (en) * 2001-09-25 2011-12-14 株式会社イノアックコーポレーション Fluid mixing mechanism
EP1446104B2 (en) 2001-11-01 2011-08-03 Novartis AG Spray drying methods
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
JP2006507921A (en) * 2002-06-28 2006-03-09 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ Method and apparatus for fluid dispersion
GB0307428D0 (en) 2003-03-31 2003-05-07 Medical Res Council Compartmentalised combinatorial chemistry
US20060078893A1 (en) 2004-10-12 2006-04-13 Medical Research Council Compartmentalised combinatorial chemistry by microfluidic control
GB0307403D0 (en) 2003-03-31 2003-05-07 Medical Res Council Selection by compartmentalised screening
EP2266687A3 (en) * 2003-04-10 2011-06-29 The President and Fellows of Harvard College Formation and control of fluidic species
ATE520935T1 (en) 2003-05-21 2011-09-15 Alexza Pharmaceuticals Inc USE OF A SOLID FUEL LAYER, METHOD FOR PRODUCING SUCH A LAYER AND ASSOCIATED HEATING DEVICE
US20040235308A1 (en) 2003-05-22 2004-11-25 Dainippon Screen Mfg. Co., Ltd. Substrate treatment method and sustrate treatment apparatus
CN104069784B (en) 2003-08-27 2017-01-11 哈佛大学 electronic control of fluidic species
US20050221339A1 (en) 2004-03-31 2005-10-06 Medical Research Council Harvard University Compartmentalised screening by microfluidic control
US9477233B2 (en) 2004-07-02 2016-10-25 The University Of Chicago Microfluidic system with a plurality of sequential T-junctions for performing reactions in microdroplets
ES2264608B2 (en) 2004-09-30 2007-08-16 Universidad De Sevilla DEVICE AND PROCEDURE FOR THE PNEUMATIC ATOMIZATION OF LIQUIDS BY IMPLOSIVE GAS FLOW.
US7968287B2 (en) 2004-10-08 2011-06-28 Medical Research Council Harvard University In vitro evolution in microfluidic systems
ES2265270B1 (en) * 2005-04-18 2008-01-01 Universidad De Sevilla PROCEDURE AND DEVICE FOR MICRO-MIXING OF FLUIDS BY REFLUGE CELL.
WO2006089984A1 (en) 2005-01-17 2006-08-31 Universidad De Sevilla Method and device for the micromixing of fluids using a reflux cell
EP1861194A2 (en) 2005-03-04 2007-12-05 The President and Fellows of Harvard College Method and apparatus for forming multiple emulsions
CA2636855C (en) 2006-01-11 2016-09-27 Raindance Technologies, Inc. Microfluidic devices and methods of use in the formation and control of nanoreactors
EP2047910B1 (en) 2006-05-11 2012-01-11 Raindance Technologies, Inc. Microfluidic device and method
US9562837B2 (en) 2006-05-11 2017-02-07 Raindance Technologies, Inc. Systems for handling microfludic droplets
EP2077912B1 (en) 2006-08-07 2019-03-27 The President and Fellows of Harvard College Fluorocarbon emulsion stabilizing surfactants
US8772046B2 (en) 2007-02-06 2014-07-08 Brandeis University Manipulation of fluids and reactions in microfluidic systems
WO2008112661A2 (en) 2007-03-09 2008-09-18 Alexza Pharmaceuticals, Inc. Heating unit for use in a drug delivery device
US7776927B2 (en) 2007-03-28 2010-08-17 President And Fellows Of Harvard College Emulsions and techniques for formation
WO2008130623A1 (en) 2007-04-19 2008-10-30 Brandeis University Manipulation of fluids, fluid components and reactions in microfluidic systems
WO2009129547A1 (en) 2008-04-18 2009-10-22 The Board Of Trustees Of The University Of Alabama Meso-scaled combustion system
WO2010009365A1 (en) 2008-07-18 2010-01-21 Raindance Technologies, Inc. Droplet libraries
US20100176063A1 (en) * 2009-01-12 2010-07-15 Yuri Kokotov Method for coalescence induced liquid-liquid separations and apparatus thereof
WO2010111231A1 (en) 2009-03-23 2010-09-30 Raindance Technologies, Inc. Manipulation of microfluidic droplets
JP5869482B2 (en) 2009-09-02 2016-02-24 プレジデント アンド フェローズ オブ ハーバード カレッジ Multiple emulsions produced using jetting and other techniques
WO2011042564A1 (en) 2009-10-09 2011-04-14 Universite De Strasbourg Labelled silica-based nanomaterial with enhanced properties and uses thereof
EP2517025B1 (en) 2009-12-23 2019-11-27 Bio-Rad Laboratories, Inc. Methods for reducing the exchange of molecules between droplets
US9399797B2 (en) 2010-02-12 2016-07-26 Raindance Technologies, Inc. Digital analyte analysis
US9366632B2 (en) 2010-02-12 2016-06-14 Raindance Technologies, Inc. Digital analyte analysis
US10351905B2 (en) 2010-02-12 2019-07-16 Bio-Rad Laboratories, Inc. Digital analyte analysis
EP2534267B1 (en) 2010-02-12 2018-04-11 Raindance Technologies, Inc. Digital analyte analysis
EP2576078B1 (en) 2010-05-28 2018-04-25 Arizona Board of Regents acting for and on behalf of Arizona State University Apparatus and methods for a gas dynamic virtual nozzle
US20120048963A1 (en) 2010-08-26 2012-03-01 Alexza Pharmaceuticals, Inc. Heat Units Using a Solid Fuel Capable of Undergoing an Exothermic Metal Oxidation-Reduction Reaction Propagated without an Igniter
WO2012045012A2 (en) 2010-09-30 2012-04-05 Raindance Technologies, Inc. Sandwich assays in droplets
EP2673614B1 (en) 2011-02-11 2018-08-01 Raindance Technologies, Inc. Method for forming mixed droplets
EP2675819B1 (en) 2011-02-18 2020-04-08 Bio-Rad Laboratories, Inc. Compositions and methods for molecular labeling
KR20140034242A (en) 2011-05-23 2014-03-19 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 Control of emulsions, including multiple emulsions
DE202012013668U1 (en) 2011-06-02 2019-04-18 Raindance Technologies, Inc. enzyme quantification
US8841071B2 (en) 2011-06-02 2014-09-23 Raindance Technologies, Inc. Sample multiplexing
US20140220350A1 (en) 2011-07-06 2014-08-07 President And Fellows Of Harvard College Multiple emulsions and techniques for the formation of multiple emulsions
US8658430B2 (en) 2011-07-20 2014-02-25 Raindance Technologies, Inc. Manipulating droplet size
EP2777818A1 (en) 2013-03-15 2014-09-17 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Method and device of producing an intermittent liquid jet
EP2991768B1 (en) 2013-04-30 2018-11-21 Arizona Board of Regents on behalf of Arizona State University Apparatus and methods for lipidic cubic phase (lcp) injection for membrane protein investigations
US11901041B2 (en) 2013-10-04 2024-02-13 Bio-Rad Laboratories, Inc. Digital analysis of nucleic acid modification
US9944977B2 (en) 2013-12-12 2018-04-17 Raindance Technologies, Inc. Distinguishing rare variations in a nucleic acid sequence from a sample
WO2015103367A1 (en) 2013-12-31 2015-07-09 Raindance Technologies, Inc. System and method for detection of rna species
SI3268072T1 (en) 2015-03-11 2024-03-29 Alexza Pharmaceuticals, Inc. Use of antistatic materials in the airway for thermal aerosol condensation process
CN108348933B (en) 2015-08-28 2022-01-28 明尼苏达州大学董事会 Nozzle and method of mixing fluid streams
US10647981B1 (en) 2015-09-08 2020-05-12 Bio-Rad Laboratories, Inc. Nucleic acid library generation methods and compositions
ES2663217B1 (en) * 2016-10-10 2019-02-07 Ingeniatrics Tecnologias S L Apparatus and method for mixing at least two liquids
US11872583B2 (en) 2018-06-14 2024-01-16 Regents Of The University Of Minnesota Counterflow mixer and atomizer
US10369579B1 (en) 2018-09-04 2019-08-06 Zyxogen, Llc Multi-orifice nozzle for droplet atomization
CN115228642A (en) * 2022-08-02 2022-10-25 北京航空航天大学 Small-flow dispersion flow atomizing nozzle and low-flow-velocity atomizer

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0899017A1 (en) * 1996-05-13 1999-03-03 Universidad De Sevilla, Vicerrectorado De Investigacion Liquid atomization process

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JPH05138080A (en) * 1991-11-25 1993-06-01 Matsushita Electric Ind Co Ltd Atomization device
US5868322A (en) * 1996-01-31 1999-02-09 Hewlett-Packard Company Apparatus for forming liquid droplets having a mechanically fixed inner microtube
US5884846A (en) * 1996-09-19 1999-03-23 Tan; Hsiaoming Sherman Pneumatic concentric nebulizer with adjustable and capillaries
WO1999031019A1 (en) 1997-12-17 1999-06-24 Universidad De Sevilla Device and method for creating spherical particles of uniform size

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0899017A1 (en) * 1996-05-13 1999-03-03 Universidad De Sevilla, Vicerrectorado De Investigacion Liquid atomization process

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO0076673A1 *

Also Published As

Publication number Publication date
EP1192009A1 (en) 2002-04-03
AU5331800A (en) 2001-01-02
AU767486B2 (en) 2003-11-13
CA2374232C (en) 2013-08-20
EP1192009B1 (en) 2013-05-01
CA2374232A1 (en) 2000-12-21
ES2424713T3 (en) 2013-10-07
WO2000076673A1 (en) 2000-12-21
JP2003501257A (en) 2003-01-14
ES2424713T4 (en) 2014-01-23

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