EP1144448A3 - Tiam2 (t-cell lymphoma invasion and metastasis 2) nucleotide exchange factor - Google Patents

Tiam2 (t-cell lymphoma invasion and metastasis 2) nucleotide exchange factor

Info

Publication number
EP1144448A3
EP1144448A3 EP00902369A EP00902369A EP1144448A3 EP 1144448 A3 EP1144448 A3 EP 1144448A3 EP 00902369 A EP00902369 A EP 00902369A EP 00902369 A EP00902369 A EP 00902369A EP 1144448 A3 EP1144448 A3 EP 1144448A3
Authority
EP
European Patent Office
Prior art keywords
tiam2
metastasis
cell lymphoma
nucleotide exchange
exchange factor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP00902369A
Other languages
German (de)
French (fr)
Other versions
EP1144448A2 (en
Inventor
David Duhl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Corp filed Critical Chiron Corp
Publication of EP1144448A2 publication Critical patent/EP1144448A2/en
Publication of EP1144448A3 publication Critical patent/EP1144448A3/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
EP00902369A 1999-01-06 2000-01-06 Tiam2 (t-cell lymphoma invasion and metastasis 2) nucleotide exchange factor Withdrawn EP1144448A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22727899A 1999-01-06 1999-01-06
US227278 1999-01-06
PCT/US2000/000459 WO2000040607A2 (en) 1999-01-06 2000-01-06 Tiam2 (t-cell lymphoma invasion and metastasis 2) nucleotide exchange factor

Publications (2)

Publication Number Publication Date
EP1144448A2 EP1144448A2 (en) 2001-10-17
EP1144448A3 true EP1144448A3 (en) 2002-03-06

Family

ID=22852486

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00902369A Withdrawn EP1144448A3 (en) 1999-01-06 2000-01-06 Tiam2 (t-cell lymphoma invasion and metastasis 2) nucleotide exchange factor

Country Status (4)

Country Link
EP (1) EP1144448A3 (en)
JP (3) JP4707235B2 (en)
AU (1) AU2409700A (en)
WO (1) WO2000040607A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002026817A2 (en) * 2000-09-25 2002-04-04 Millennium Pharmaceuticals, Inc. 33521, a human guanine nucleotide exchange family member and uses thereof
EP1752040A1 (en) * 2005-08-12 2007-02-14 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Isolation of the t-complex distorters and applications thereof
US8679760B2 (en) * 2011-05-03 2014-03-25 National Cheng Kung University Biomarker and method for evaluating risk of proliferation, invasion, or metastasis of cancer
JP6675287B2 (en) 2016-08-23 2020-04-01 日機装株式会社 Fluid sterilizer

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997046680A1 (en) * 1996-06-05 1997-12-11 Chiron Corporation Dna encoding dp. 75 and a process for its use

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997046680A1 (en) * 1996-06-05 1997-12-11 Chiron Corporation Dna encoding dp. 75 and a process for its use

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
CHIU C.Y. ET AL.: "Cloning and characterization of T-cell lymphoma invasion and metastasis 2 (TIAM2), a novel guanine nucleotide exchange factor related to TIAM1.", GENOMICS, vol. 61, no. 1, 1 October 1999 (1999-10-01), pages 66-73, XP000864676 *
CHIU C.Y. ET AL.: "Erratum: Cloning and characterization of T-cell lymphoma invasion and metastasis 2 (TIAM2), a novel guanine nucleotide exchange factor related to TIAM1.", GENOMICS, vol. 63, no. 3, 2000, pages 439, XP000864677 *
HOSHINO M. ET AL.: "Identification of the stef Gene That Encodes a Novel Guanine Nucleotide Exchange Factor Specific for Rac1", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 274, no. 25, 18 June 1999 (1999-06-18), pages 17837 - 17844, XP002141545 *
HOSHINO M.: "Mus musculus Stef mRNA for sif and Tiam1-like exchange factor, complete cds", EMBL DATABASE ENTRY AB022915; ACCESSION NO. AB022915, 30 June 1999 (1999-06-30), XP002141546 *
LEEUWEN F.N. ET AL.: "The Guanine Nucleotide Exchange Factor Tiam1 Affects Neuronal Morphology; Opposing Roles for the Small GTPases Rac and Rho", JOURNAL OF CELL BIOLOGY, vol. 139, no. 3, 3 November 1997 (1997-11-03), pages 797 - 807, XP002141547 *

Also Published As

Publication number Publication date
JP2010233574A (en) 2010-10-21
AU2409700A (en) 2000-07-24
WO2000040607A3 (en) 2001-11-01
JP2011083295A (en) 2011-04-28
JP2002538774A (en) 2002-11-19
WO2000040607A2 (en) 2000-07-13
JP4707235B2 (en) 2011-06-22
EP1144448A2 (en) 2001-10-17

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