EP1100950A4 - Antikörperfabriken gastrointestinaler bakterien - Google Patents

Antikörperfabriken gastrointestinaler bakterien

Info

Publication number
EP1100950A4
EP1100950A4 EP99938901A EP99938901A EP1100950A4 EP 1100950 A4 EP1100950 A4 EP 1100950A4 EP 99938901 A EP99938901 A EP 99938901A EP 99938901 A EP99938901 A EP 99938901A EP 1100950 A4 EP1100950 A4 EP 1100950A4
Authority
EP
European Patent Office
Prior art keywords
gastrointestinal bacterial
bacterial antibody
antibody factories
factories
gastrointestinal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99938901A
Other languages
English (en)
French (fr)
Other versions
EP1100950A1 (de
Inventor
William E Fahl
Geoffrey J Letchworth
Gerald C Mueller
Adam K Savage
Deborah Loo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wisconsin Alumni Research Foundation
Original Assignee
Wisconsin Alumni Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Research Foundation filed Critical Wisconsin Alumni Research Foundation
Publication of EP1100950A1 publication Critical patent/EP1100950A1/de
Publication of EP1100950A4 publication Critical patent/EP1100950A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/542—Mucosal route oral/gastrointestinal
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP99938901A 1998-07-30 1999-07-29 Antikörperfabriken gastrointestinaler bakterien Withdrawn EP1100950A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9469798P 1998-07-30 1998-07-30
US94697P 1998-07-30
PCT/US1999/017296 WO2000006764A1 (en) 1998-07-30 1999-07-29 Gastrointestinal bacterial antibody factories

Publications (2)

Publication Number Publication Date
EP1100950A1 EP1100950A1 (de) 2001-05-23
EP1100950A4 true EP1100950A4 (de) 2002-10-16

Family

ID=22246653

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99938901A Withdrawn EP1100950A4 (de) 1998-07-30 1999-07-29 Antikörperfabriken gastrointestinaler bakterien

Country Status (6)

Country Link
EP (1) EP1100950A4 (de)
JP (1) JP2002521494A (de)
AU (1) AU5328599A (de)
CA (1) CA2338001A1 (de)
IL (1) IL141142A0 (de)
WO (1) WO2000006764A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0516681A (pt) 2004-11-25 2008-09-16 Unilever Nv sistema de entrega de anticorpos ao trato gastrointestinal, vetor de expressão, microorganismos transformados, método de entrega de anticorpos, imunoglobulinas de cadeia pesada e seu uso, produto alimentìcio e seu método de fabricação e utensìlio de distribuição
BRPI0615547A2 (pt) * 2005-08-19 2011-05-24 Unilever Nv produto alimentìcio, preparação farmacêutica, método de fabricação de produto alimentìcio, método de fabricação de preparação farmacêutica, uso do produto alimentìcio, usos da preparação farmacêutica, método de fornecimento de benefìcios à saúde do intestino e implementos de liberação para uso com produto alimentìcio
EP2097452A1 (de) * 2006-12-14 2009-09-09 Actogenix N.V. Verabreichung von bindungsmolekülen zur induktion einer immunomodulation
WO2012141540A2 (ko) * 2011-04-13 2012-10-18 씨제이제일제당 (주) 바이러스 감염 억제 활성을 갖는 신규 분리한 락토바실러스 퍼멘텀 균주
KR20150037953A (ko) * 2012-07-13 2015-04-08 각코호진 데이쿄 헤이세이 다이가쿠 항종양제, 종양 검출용 마커 및 경구 백신제
PL2875121T3 (pl) * 2012-07-20 2018-06-29 Prevtec Microbia Inc. Niepatogenny szczep E. coli F18 i jego zastosowanie

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994021284A1 (en) * 1993-03-15 1994-09-29 Pharma Pacific Pty. Ltd. Therapeutic formulation and method
WO1997020577A1 (en) * 1995-12-06 1997-06-12 Pharma Pacific Pty. Ltd. Improved therapeutic formulation and method

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4571385A (en) * 1983-06-27 1986-02-18 The United States Of America As Represented By The Department Of Health And Human Services Genetic reassortment of rotaviruses for production of vaccines and vaccine precursors
DE3581400D1 (de) * 1984-09-28 1991-02-21 Teijin Ltd Maus/mensch-hybridoma mit erzeugung von antiviralen menschlichen antikoerpern, deren herstellung und antivirale menschliche monoklonale antikoerper.
US4956452A (en) * 1987-06-14 1990-09-11 The University Of Maryland Monoclonal antibody which neutralizes multiple strains of infectious bursal disease virus
US5637677A (en) * 1987-07-16 1997-06-10 The Trustees Of The University Of Pennsylvania Biologically active compounds and methods of constructing and using the same
US5531988A (en) * 1994-10-28 1996-07-02 Metagenics, Inc. Bacteria and immunoglobulin-containing composition for human gastrointestinal health
US5733540A (en) * 1995-03-08 1998-03-31 Lee; Peter Poon-Hang Protection from viral infection via colonization of mucosal membranes with genetically modified bacteria
US5895758A (en) * 1997-06-10 1999-04-20 Bio-Energy Systems Strain of lactobacillus Plantarum

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994021284A1 (en) * 1993-03-15 1994-09-29 Pharma Pacific Pty. Ltd. Therapeutic formulation and method
WO1997020577A1 (en) * 1995-12-06 1997-06-12 Pharma Pacific Pty. Ltd. Improved therapeutic formulation and method

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
PLUECKTHUN ANDREAS ET AL: "New protein engineering approaches to multivalent and bispecific antibody fragments.", IMMUNOTECHNOLOGY (SHANNON), vol. 3, no. 2, 1997, pages 83 - 105, XP004126672, ISSN: 1380-2933 *
POUWELS P H ET AL: "Lactic acid bacteria as antigen delivery vehicles for oral immunization purposes.", INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY. NETHERLANDS 26 MAY 1998, vol. 41, no. 2, 26 May 1998 (1998-05-26), pages 155 - 167, XP002209511, ISSN: 0168-1605 *
ROBINSON KAREN ET AL: "Oral vaccination of mice against tetanus with recombinant Lactococcus lactis.", NATURE BIOTECHNOLOGY, vol. 15, no. 7, 1997, pages 653 - 657, XP001093957, ISSN: 1087-0156 *
RUSH C ET AL: "Protein A as a fusion partner for the expression of heterologous proteins in Lactobacillus.", APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, vol. 47, no. 5, 1997, pages 537 - 542, XP002209512, ISSN: 0175-7598 *
See also references of WO0006764A1 *
SHIBATA YASUKO ET AL: "Construction of a functional single-chain variable fragment antibody against hemagglutinin from Porphyromonas gingivalis.", INFECTION AND IMMUNITY, vol. 66, no. 5, May 1998 (1998-05-01), pages 2207 - 2212, XP001097761, ISSN: 0019-9567 *

Also Published As

Publication number Publication date
WO2000006764A1 (en) 2000-02-10
EP1100950A1 (de) 2001-05-23
IL141142A0 (en) 2002-02-10
AU5328599A (en) 2000-02-21
CA2338001A1 (en) 2000-02-10
JP2002521494A (ja) 2002-07-16

Similar Documents

Publication Publication Date Title
GB9809839D0 (en) Antibody
PT2261358E (pt) Antigénios de streptococcus
GB9911569D0 (en) Antibodies
GB9808145D0 (en) Assay
IL141142A0 (en) Gastrointestinal bacterial antibody factories
GB9818915D0 (en) Antibodies
GB9828700D0 (en) Antibody
GB9803156D0 (en) Assay
GB9809160D0 (en) Assay
GB9819411D0 (en) Antibodies
GB9825184D0 (en) Antigen
GB9827845D0 (en) Immunoassay or proteins
KR200203130Y1 (en) Apartment
GB9800760D0 (en) Antigens
GB9816327D0 (en) Antibody
ZA983532B (en) Sensors.
GB9816280D0 (en) Antibody combination
GB9817097D0 (en) Gastrointestinal function
AUPP160198A0 (en) Prefabricated factories
GB9822143D0 (en) Antigens
GB9819015D0 (en) Antigens
GB9804779D0 (en) Chemical modification
GB9812533D0 (en) Bacterial protein
GB9815305D0 (en) Elelctrochemical sensors
ZA982196B (en) Cercosporin-degrading bacteria

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20010207

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

AX Request for extension of the european patent

Free format text: AL;LT;LV;MK;RO;SI

A4 Supplementary search report drawn up and despatched

Effective date: 20020902

AK Designated contracting states

Kind code of ref document: A4

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20040203