EP1090412A4 - Mass spectrometry with multipole ion guides - Google Patents

Mass spectrometry with multipole ion guides

Info

Publication number
EP1090412A4
EP1090412A4 EP99953401A EP99953401A EP1090412A4 EP 1090412 A4 EP1090412 A4 EP 1090412A4 EP 99953401 A EP99953401 A EP 99953401A EP 99953401 A EP99953401 A EP 99953401A EP 1090412 A4 EP1090412 A4 EP 1090412A4
Authority
EP
European Patent Office
Prior art keywords
mass spectrometry
ion guides
multipole ion
multipole
guides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP99953401A
Other languages
German (de)
French (fr)
Other versions
EP1090412A1 (en
EP1090412B1 (en
Inventor
Craig M Whitehouse
Bruce A Andrien Jr
Erol E Gulcicek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Revvity Health Sciences Inc
Original Assignee
Analytica of Branford Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Analytica of Branford Inc filed Critical Analytica of Branford Inc
Publication of EP1090412A1 publication Critical patent/EP1090412A1/en
Publication of EP1090412A4 publication Critical patent/EP1090412A4/en
Application granted granted Critical
Publication of EP1090412B1 publication Critical patent/EP1090412B1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/06—Electron- or ion-optical arrangements
    • H01J49/062—Ion guides
    • H01J49/063—Multipole ion guides, e.g. quadrupoles, hexapoles
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/4205—Device types
    • H01J49/422—Two-dimensional RF ion traps
    • H01J49/4225—Multipole linear ion traps, e.g. quadrupoles, hexapoles
EP99953401.9A 1998-05-29 1999-05-29 Mass spectrometry with multipole ion guides Expired - Lifetime EP1090412B1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US235946 1994-05-02
US8724698P 1998-05-29 1998-05-29
US87246P 1998-05-29
US23594699A 1999-01-22 1999-01-22
PCT/US1999/012169 WO1999062101A1 (en) 1998-05-29 1999-05-29 Mass spectrometry with multipole ion guides

Publications (3)

Publication Number Publication Date
EP1090412A1 EP1090412A1 (en) 2001-04-11
EP1090412A4 true EP1090412A4 (en) 2006-01-25
EP1090412B1 EP1090412B1 (en) 2014-03-05

Family

ID=26776766

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99953401.9A Expired - Lifetime EP1090412B1 (en) 1998-05-29 1999-05-29 Mass spectrometry with multipole ion guides

Country Status (5)

Country Link
EP (1) EP1090412B1 (en)
JP (1) JP2002517070A (en)
AU (1) AU4326599A (en)
CA (2) CA2626383C (en)
WO (1) WO1999062101A1 (en)

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CA2326514A1 (en) * 2000-01-10 2001-07-10 Mds Inc. An apparatus for and method of discriminating against unwanted ionized species in mass spectrometry with collision and reaction devices
US6720554B2 (en) * 2000-07-21 2004-04-13 Mds Inc. Triple quadrupole mass spectrometer with capability to perform multiple mass analysis steps
US6642514B2 (en) 2000-11-29 2003-11-04 Micromass Limited Mass spectrometers and methods of mass spectrometry
US20020115056A1 (en) 2000-12-26 2002-08-22 Goodlett David R. Rapid and quantitative proteome analysis and related methods
US6956205B2 (en) 2001-06-15 2005-10-18 Bruker Daltonics, Inc. Means and method for guiding ions in a mass spectrometer
JP3620479B2 (en) * 2001-07-31 2005-02-16 株式会社島津製作所 Method of ion selection in ion storage device
WO2003056604A1 (en) * 2001-12-21 2003-07-10 Mds Inc., Doing Business As Mds Sciex Use of notched broadband waveforms in a linear ion trap
GB0210930D0 (en) 2002-05-13 2002-06-19 Thermo Electron Corp Improved mass spectrometer and mass filters therefor
EP1367633B1 (en) * 2002-05-30 2006-09-06 Micromass UK Limited Mass spectrometer
US7095013B2 (en) 2002-05-30 2006-08-22 Micromass Uk Limited Mass spectrometer
WO2003102508A1 (en) 2002-05-31 2003-12-11 Analytica Of Branford, Inc. Mass spectrometry with segmented rf multiple ion guides in various pressure regions
US7034292B1 (en) 2002-05-31 2006-04-25 Analytica Of Branford, Inc. Mass spectrometry with segmented RF multiple ion guides in various pressure regions
GB0305796D0 (en) 2002-07-24 2003-04-16 Micromass Ltd Method of mass spectrometry and a mass spectrometer
CA2514343C (en) * 2003-01-24 2010-04-06 Thermo Finnigan Llc Controlling ion populations in a mass analyzer
CA2431603C (en) 2003-06-10 2012-03-27 Micromass Uk Limited Mass spectrometer
DE10326156B4 (en) * 2003-06-10 2011-12-01 Micromass Uk Ltd. Mass spectrometer with gas collision cell and AC or RF ion guide with differential pressure ranges and associated methods for mass spectrometry
DE102004014582B4 (en) * 2004-03-25 2009-08-20 Bruker Daltonik Gmbh Ion optical phase volume compression
JP2005276787A (en) * 2004-03-26 2005-10-06 Tsutomu Masujima Mass spectrometer
US20050242281A1 (en) * 2004-04-30 2005-11-03 Gangqiang Li Unevenly segmented multipole
GB0416288D0 (en) * 2004-07-21 2004-08-25 Micromass Ltd Mass spectrometer
JP4848657B2 (en) * 2005-03-28 2011-12-28 株式会社島津製作所 MS / MS mass spectrometer
GB0506288D0 (en) * 2005-03-29 2005-05-04 Thermo Finnigan Llc Improvements relating to mass spectrometry
GB2427067B (en) * 2005-03-29 2010-02-24 Thermo Finnigan Llc Improvements relating to ion trapping
JP5252205B2 (en) * 2006-01-05 2013-07-31 エムディーエス インコーポレイテッド Information-dependent collection triggered by mass defect
US7378653B2 (en) * 2006-01-10 2008-05-27 Varian, Inc. Increasing ion kinetic energy along axis of linear ion processing devices
GB0624679D0 (en) * 2006-12-11 2007-01-17 Shimadzu Corp A time-of-flight mass spectrometer and a method of analysing ions in a time-of-flight mass spectrometer
US8507850B2 (en) 2007-05-31 2013-08-13 Perkinelmer Health Sciences, Inc. Multipole ion guide interface for reduced background noise in mass spectrometry
JP2008108739A (en) * 2007-11-26 2008-05-08 Hitachi High-Technologies Corp Mass spectroscope and measurement system provided with the same
JP5498958B2 (en) * 2008-01-30 2014-05-21 ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド Ion fragmentation in mass spectrometry.
GB2484136B (en) * 2010-10-01 2015-09-16 Thermo Fisher Scient Bremen Method and apparatus for improving the throughput of a charged particle analysis system
CN103329241B (en) 2010-11-26 2016-08-31 耶拿分析仪器股份公司 Mass spectral analysis aspect or relevant improvement
JP2011119279A (en) * 2011-03-11 2011-06-16 Hitachi High-Technologies Corp Mass spectrometer, and measuring system using the same
JP2015507334A (en) * 2012-02-01 2015-03-05 ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド Method and apparatus for improved sensitivity in a mass spectrometer
WO2014197348A2 (en) * 2013-06-03 2014-12-11 Perkinelmer Health Sciences, Inc. Ion guide or filters with selected gas conductance
GB201715777D0 (en) 2017-09-29 2017-11-15 Shimadzu Corp ION Trap
KR102305532B1 (en) * 2020-03-04 2021-09-27 한국원자력안전기술원 Qualitative and quantitative analysis apparatus and method for inert gas
CN111640646A (en) * 2020-06-15 2020-09-08 成都艾立本科技有限公司 High-sensitivity proton transfer time-of-flight mass spectrometer and method for measuring ion time-of-flight by using same
CN111613514B (en) * 2020-06-24 2023-11-03 成都艾立本科技有限公司 High-sensitivity ultraviolet ionization time-of-flight mass spectrometer and ion time-of-flight measurement method
JPWO2022239104A1 (en) * 2021-05-11 2022-11-17
US11501962B1 (en) * 2021-06-17 2022-11-15 Thermo Finnigan Llc Device geometries for controlling mass spectrometer pressures
GB202114780D0 (en) * 2021-10-15 2021-12-01 Thermo Fisher Scient Bremen Gmbh Ion transport between ion optical devices at different gas pressures

Citations (2)

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Publication number Priority date Publication date Assignee Title
GB2299446A (en) * 1995-03-28 1996-10-02 Bruker Franzen Analytik Gmbh Mass spectrometers
WO1998006481A1 (en) * 1996-08-09 1998-02-19 Analytica Of Branford, Inc. Multipole ion guide ion trap mass spectrometry

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EP0237259A3 (en) * 1986-03-07 1989-04-05 Finnigan Corporation Mass spectrometer
US5179278A (en) * 1991-08-23 1993-01-12 Mds Health Group Limited Multipole inlet system for ion traps
CA2656956C (en) 1994-02-28 2011-10-11 Analytica Of Branford, Inc. Multipole ion guide for mass spectrometry
EP0871201B1 (en) * 1995-07-03 2010-09-15 Hitachi, Ltd. Mass spectrometer
EP0843887A1 (en) * 1995-08-11 1998-05-27 Mds Health Group Limited Spectrometer with axial field
AU718774B2 (en) * 1996-06-06 2000-04-20 Mds Inc. Axial ejection in a multipole mass spectrometer
CA2312806A1 (en) * 1997-12-05 1999-06-17 University Of British Columbia Method of analyzing ions in an apparatus including a time of flight mass spectrometer and a linear ion trap
EP1057209B1 (en) * 1998-01-23 2011-11-23 PerkinElmer Health Sciences, Inc. Mass spectrometry with multipole ion guide

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2299446A (en) * 1995-03-28 1996-10-02 Bruker Franzen Analytik Gmbh Mass spectrometers
WO1998006481A1 (en) * 1996-08-09 1998-02-19 Analytica Of Branford, Inc. Multipole ion guide ion trap mass spectrometry

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHENG X ET AL: "Interface for a Four-Sector Mass Spectrometer with a Dual-Purpose Collision Cell: High Transmission at Low to Intermediate Energies", JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, ELSEVIER SCIENCE INC, US, vol. 6, no. 3, March 1995 (1995-03-01), pages 175 - 186, XP004052030, ISSN: 1044-0305 *
See also references of WO9962101A1 *

Also Published As

Publication number Publication date
WO1999062101A9 (en) 2000-03-02
CA2332534A1 (en) 1999-12-02
CA2332534C (en) 2008-07-22
EP1090412A1 (en) 2001-04-11
JP2002517070A (en) 2002-06-11
CA2626383A1 (en) 1999-12-02
WO1999062101A1 (en) 1999-12-02
CA2626383C (en) 2011-07-19
AU4326599A (en) 1999-12-13
EP1090412B1 (en) 2014-03-05

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