EP1073710A4 - NON-STOCHASTIC DEVELOPMENT OF GENETIC VACCINES AND ENZYMES - Google Patents

NON-STOCHASTIC DEVELOPMENT OF GENETIC VACCINES AND ENZYMES

Info

Publication number
EP1073710A4
EP1073710A4 EP00913378A EP00913378A EP1073710A4 EP 1073710 A4 EP1073710 A4 EP 1073710A4 EP 00913378 A EP00913378 A EP 00913378A EP 00913378 A EP00913378 A EP 00913378A EP 1073710 A4 EP1073710 A4 EP 1073710A4
Authority
EP
European Patent Office
Prior art keywords
enzymes
stochastic generation
genetic vaccines
vaccines
genetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP00913378A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP1073710A3 (en
EP1073710A2 (en
Inventor
Jay M Short
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BP Corp North America Inc
Original Assignee
Verenium Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/246,178 external-priority patent/US6171820B1/en
Priority claimed from US09/267,118 external-priority patent/US6238884B1/en
Priority claimed from US09/276,860 external-priority patent/US6352842B1/en
Priority claimed from US09/332,835 external-priority patent/US6537776B1/en
Application filed by Verenium Corp filed Critical Verenium Corp
Priority to EP11167668A priority Critical patent/EP2397549A3/en
Publication of EP1073710A3 publication Critical patent/EP1073710A3/en
Publication of EP1073710A2 publication Critical patent/EP1073710A2/en
Publication of EP1073710A4 publication Critical patent/EP1073710A4/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/445—Plasmodium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102—Mutagenizing nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102—Mutagenizing nucleic acids
    • C12N15/1027—Mutagenizing nucleic acids by DNA shuffling, e.g. RSR, STEP, RPR
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1058—Directional evolution of libraries, e.g. evolution of libraries is achieved by mutagenesis and screening or selection of mixed population of organisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Ecology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP00913378A 1999-02-04 2000-02-04 NON-STOCHASTIC DEVELOPMENT OF GENETIC VACCINES AND ENZYMES Ceased EP1073710A4 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP11167668A EP2397549A3 (en) 1999-02-04 2000-02-04 Non-stochastic generation of genetic vaccines and enzymes

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US246178 1999-02-04
US09/246,178 US6171820B1 (en) 1995-12-07 1999-02-04 Saturation mutagenesis in directed evolution
US09/267,118 US6238884B1 (en) 1995-12-07 1999-03-09 End selection in directed evolution
US09/276,860 US6352842B1 (en) 1995-12-07 1999-03-26 Exonucease-mediated gene assembly in directed evolution
US09/332,835 US6537776B1 (en) 1999-06-14 1999-06-14 Synthetic ligation reassembly in directed evolution
PCT/US2000/003086 WO2000046344A2 (en) 1999-02-04 2000-02-04 Non-stochastic generation of genetic vaccines and enzymes

Publications (3)

Publication Number Publication Date
EP1073710A3 EP1073710A3 (en) 2000-12-28
EP1073710A2 EP1073710A2 (en) 2001-02-07
EP1073710A4 true EP1073710A4 (en) 2007-12-19

Family

ID=27500214

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00913378A Ceased EP1073710A4 (en) 1999-02-04 2000-02-04 NON-STOCHASTIC DEVELOPMENT OF GENETIC VACCINES AND ENZYMES

Country Status (3)

Country Link
EP (1) EP1073710A4 (es)
IL (1) IL138206A (es)
MX (1) MXPA00009723A (es)

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991015581A1 (en) * 1990-04-05 1991-10-17 Roberto Crea Walk-through mutagenesis
WO1997020078A1 (en) * 1995-11-30 1997-06-05 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
WO1998027230A1 (en) * 1996-12-18 1998-06-25 Maxygen, Inc. Methods and compositions for polypeptide engineering
WO1998032845A1 (en) * 1997-01-24 1998-07-30 Bioinvent International Ab A method for in vitro molecular evolution of protein function
WO1998042832A1 (en) * 1997-03-25 1998-10-01 California Institute Of Technology Recombination of polynucleotide sequences using random or defined primers
WO1999041368A2 (en) * 1998-02-11 1999-08-19 Maxygen, Inc. Optimization of immunomodulatory properties of genetic vaccines
WO2000053744A2 (en) * 1999-03-09 2000-09-14 Diversa Corporation End selection in directed evolution
WO2000058517A1 (en) * 1999-03-26 2000-10-05 Diversa Corporation Exonuclease-mediated nucleic acid reassembly in directed evolution
WO2000077262A1 (en) * 1999-06-14 2000-12-21 Diversa Corporation Synthetic ligation reassembly in directed evolution

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991015581A1 (en) * 1990-04-05 1991-10-17 Roberto Crea Walk-through mutagenesis
WO1997020078A1 (en) * 1995-11-30 1997-06-05 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
WO1998027230A1 (en) * 1996-12-18 1998-06-25 Maxygen, Inc. Methods and compositions for polypeptide engineering
WO1998032845A1 (en) * 1997-01-24 1998-07-30 Bioinvent International Ab A method for in vitro molecular evolution of protein function
WO1998042832A1 (en) * 1997-03-25 1998-10-01 California Institute Of Technology Recombination of polynucleotide sequences using random or defined primers
WO1999041368A2 (en) * 1998-02-11 1999-08-19 Maxygen, Inc. Optimization of immunomodulatory properties of genetic vaccines
WO2000053744A2 (en) * 1999-03-09 2000-09-14 Diversa Corporation End selection in directed evolution
WO2000058517A1 (en) * 1999-03-26 2000-10-05 Diversa Corporation Exonuclease-mediated nucleic acid reassembly in directed evolution
WO2000077262A1 (en) * 1999-06-14 2000-12-21 Diversa Corporation Synthetic ligation reassembly in directed evolution

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
MARKS J D ET AL: "Molecular evolution of proteins on filamentous phage. Mimicking the strategy of the immune system", JOURNAL OF BIOLOGICAL CHEMISTRY 1992 UNITED STATES, vol. 267, no. 23, 1992, pages 16007 - 16010, XP002025816, ISSN: 0021-9258 *
REIDHAAR-OLSON J F ET AL: "COMBINATORIAL CASSETTE MUTAGENESIS AS A PROBE OF THE INFORMATIONAL CONTENT OF PROTEIN SEQUENCES", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE, US, vol. 241, 1 July 1988 (1988-07-01), pages 53 - 57, XP000652325, ISSN: 0036-8075 *
RIECHMANN L AND WEILL M: "Phage display and selection of a site-directed randomized single-chain antibody Fv fragment for its affinity improvement", BIOCHEMISTRY, AMERICAN CHEMICAL SOCIETY. EASTON, PA, US, vol. 32, no. 34, 31 August 1993 (1993-08-31), pages 8848 - 8855, XP002147197, ISSN: 0006-2960 *
SCHULTZ S ET AL: "Site-saturation studies of beta-lactamase: production and characterization of mutant beta-lactamases with all possible amino acid substitutions at residue 71", March 1986, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, US, PAGE(S) 1588-1592, ISSN: 0027-8424, XP002147196 *
SHANKLIN J ED - ZHANG QIFA WING ROD: "Exploring the possibilities presented by protein engineering", CURRENT OPINION IN PLANT BIOLOGY, QUADRANT SUBSCRIPTION SERVICES, GB, vol. 3, no. 3, 1 January 2000 (2000-01-01), pages 243 - 248, XP004793029, ISSN: 1369-5266 *
SHANKLIN J: "Exploring the possibilities presented by protein engineering", CURRENT OPINION IN PLANT BIOLOGY, QUADRANT SUBSCRIPTION SERVICES, GB, vol. 3, no. 3, 2000, pages 243 - 248, XP004793029, ISSN: 1369-5266 *

Also Published As

Publication number Publication date
MXPA00009723A (es) 2003-09-22
IL138206A (en) 2011-06-30
IL138206A0 (en) 2001-10-31
EP1073710A2 (en) 2001-02-07

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