AU2001289104A1 - Methods of producing cells and animals comprising targeted gene modifications - Google Patents
Methods of producing cells and animals comprising targeted gene modificationsInfo
- Publication number
- AU2001289104A1 AU2001289104A1 AU2001289104A AU8910401A AU2001289104A1 AU 2001289104 A1 AU2001289104 A1 AU 2001289104A1 AU 2001289104 A AU2001289104 A AU 2001289104A AU 8910401 A AU8910401 A AU 8910401A AU 2001289104 A1 AU2001289104 A1 AU 2001289104A1
- Authority
- AU
- Australia
- Prior art keywords
- animals
- methods
- producing cells
- targeted gene
- gene modifications
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 241001465754 Metazoa Species 0.000 title 1
- 238000012239 gene modification Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/65—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression using markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
- C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/32—Vector systems having a special element relevant for transcription being an silencer not forming part of the promoter region
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/42—Vector systems having a special element relevant for transcription being an intron or intervening sequence for splicing and/or stability of RNA
Landscapes
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Mycology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23295700P | 2000-09-15 | 2000-09-15 | |
US60/232,957 | 2000-09-15 | ||
PCT/US2001/028892 WO2002022834A2 (en) | 2000-09-15 | 2001-09-17 | Methods of producing cells and animals comprising targeted gene modifications |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001289104A1 true AU2001289104A1 (en) | 2002-03-26 |
Family
ID=22875252
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001289104A Abandoned AU2001289104A1 (en) | 2000-09-15 | 2001-09-17 | Methods of producing cells and animals comprising targeted gene modifications |
Country Status (3)
Country | Link |
---|---|
US (1) | US6929909B2 (en) |
AU (1) | AU2001289104A1 (en) |
WO (1) | WO2002022834A2 (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020133841A1 (en) * | 2000-12-11 | 2002-09-19 | Leviten Michael W. | Transgenic mice containing huntingtin interacting protein gene disruptions |
US20020112256A1 (en) * | 2000-12-11 | 2002-08-15 | Allen Keith D. | Transgenic mice containing proliferator-activated receptor gene disruptions |
JP2002278037A (en) * | 2001-03-22 | 2002-09-27 | Fuji Photo Film Co Ltd | Heat developing device |
US20030182673A1 (en) * | 2002-03-22 | 2003-09-25 | Allen Keith D. | Calpain large subunit (n-CL4) cysteine protease gene disruptions, and compositions and methods related thereto |
KR101068479B1 (en) | 2008-07-30 | 2011-09-29 | 한국생명공학연구원 | alpha 1,3-galactosyltransferase gene targeting vector and uses thereof |
JP6683598B2 (en) | 2013-03-15 | 2020-04-22 | マックスサイト インコーポレーティッド | Methods and compositions for producing stable transfected cells |
EP3132025B1 (en) * | 2014-04-14 | 2023-08-30 | Maxcyte, Inc. | Methods and compositions for modifying genomic dna |
WO2016168275A1 (en) | 2015-04-13 | 2016-10-20 | Maxcyte, Inc. | Methods and compositions for modifying genomic dna |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5464764A (en) * | 1989-08-22 | 1995-11-07 | University Of Utah Research Foundation | Positive-negative selection methods and vectors |
US5530178A (en) * | 1991-05-29 | 1996-06-25 | The Ontario Cancer Institute | Mutant mouse lacking CD8 surface marker |
WO1993016177A1 (en) * | 1992-02-11 | 1993-08-19 | Cell Genesys, Inc. | Homogenotization of gene-targeting events |
US5625122A (en) * | 1992-04-24 | 1997-04-29 | The Ontario Cancer Institute | Mouse having a disrupted lck gene |
AU684524B2 (en) * | 1993-06-14 | 1997-12-18 | Tet Systems Holding Gmbh & Co. Kg | Tight control of gene expression in eucaryotic cells by tetracycline-responsive promoters |
ZA989497B (en) * | 1997-10-20 | 2000-04-19 | Roche Diagnostics Gmbh | Positive-negative selection in homologous recombination. |
-
2001
- 2001-09-17 US US09/954,483 patent/US6929909B2/en not_active Expired - Fee Related
- 2001-09-17 WO PCT/US2001/028892 patent/WO2002022834A2/en active Application Filing
- 2001-09-17 AU AU2001289104A patent/AU2001289104A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US6929909B2 (en) | 2005-08-16 |
WO2002022834A3 (en) | 2003-01-30 |
US20030032175A1 (en) | 2003-02-13 |
WO2002022834A2 (en) | 2002-03-21 |
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