EP1069827A4 - Acides nucleiques codant une proteine de membrane exterieure d'agent d'ehrlichiose granulocytaire humaine - Google Patents

Acides nucleiques codant une proteine de membrane exterieure d'agent d'ehrlichiose granulocytaire humaine

Info

Publication number
EP1069827A4
EP1069827A4 EP99916535A EP99916535A EP1069827A4 EP 1069827 A4 EP1069827 A4 EP 1069827A4 EP 99916535 A EP99916535 A EP 99916535A EP 99916535 A EP99916535 A EP 99916535A EP 1069827 A4 EP1069827 A4 EP 1069827A4
Authority
EP
European Patent Office
Prior art keywords
nucleic acids
membrane protein
acids encoding
outer membrane
human granulocytic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99916535A
Other languages
German (de)
English (en)
Other versions
EP1069827A1 (fr
Inventor
Yasuko Rikhisa
Ning Zhi
Norio Ohashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ohio State University Research Foundation
Original Assignee
Ohio State University Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ohio State University Research Foundation filed Critical Ohio State University Research Foundation
Publication of EP1069827A1 publication Critical patent/EP1069827A1/fr
Publication of EP1069827A4 publication Critical patent/EP1069827A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1246—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Rickettsiales (O)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/43504—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates
    • G01N2333/43552—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates from insects
    • G01N2333/43556—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates from insects from ticks
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
EP99916535A 1998-04-09 1999-04-08 Acides nucleiques codant une proteine de membrane exterieure d'agent d'ehrlichiose granulocytaire humaine Withdrawn EP1069827A4 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US8119298P 1998-04-09 1998-04-09
US81192P 1998-04-09
US12808799P 1999-04-07 1999-04-07
US128087P 1999-04-07
PCT/US1999/007759 WO1999052370A1 (fr) 1998-04-09 1999-04-08 Acides nucleiques codant une proteine de membrane exterieure d'agent d'ehrlichiose granulocytaire humaine

Publications (2)

Publication Number Publication Date
EP1069827A1 EP1069827A1 (fr) 2001-01-24
EP1069827A4 true EP1069827A4 (fr) 2003-06-18

Family

ID=26765307

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99916535A Withdrawn EP1069827A4 (fr) 1998-04-09 1999-04-08 Acides nucleiques codant une proteine de membrane exterieure d'agent d'ehrlichiose granulocytaire humaine

Country Status (4)

Country Link
EP (1) EP1069827A4 (fr)
AU (1) AU3483599A (fr)
CA (1) CA2326717A1 (fr)
WO (1) WO1999052370A1 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2330393T3 (es) 1997-04-25 2009-12-09 Antigenics Inc. Caracterizacion de ehrlichia granulocitica y metodos de uso.
US20030194756A1 (en) * 2002-04-12 2003-10-16 O'connor Thomas Patrick Peptides for detection of antibody to Ehrlichia equi
CN100386430C (zh) * 2002-11-04 2008-05-07 研究发展基金会 用于犬和人埃利希病的免疫诊断的p153和p156抗原及其用途
US7507789B2 (en) 2007-04-09 2009-03-24 Idexx Laboratories, Inc. Detection of Anaplasma platys
US8784828B2 (en) 2007-05-04 2014-07-22 The Ohio State University Research Foundation Ehrlichia ewingii proteins, nucleic acids, and methods of their use
ES2327593B1 (es) * 2007-06-29 2010-08-05 Instituto De Salud Carlos Iii Metodo de identificacion de especies bacterianas de los generos anaplasma/ehrlichia y bartonella.
US8158370B2 (en) 2007-11-27 2012-04-17 Idexx Laboratories, Inc. Anaplasma phagocytophilum (Aph) antigens and antibodies specific for Anaplasma
WO2010042691A1 (fr) 2008-10-08 2010-04-15 Idexx Laboratories, Inc. Compositions et méthodes de détection d'anticorps spécifiques d'anaplasma phagocytophilum (aph) et d'anaplasma platys (apl)
US20140162256A1 (en) 2011-03-31 2014-06-12 Yasuko Rikihisa Compositions and methods for the detection of anaplasma platys
US10100092B2 (en) 2011-11-03 2018-10-16 Vca, Inc. Compositions and methods to detect various infectious organisms
US9133525B2 (en) 2012-01-26 2015-09-15 Luc Montagnier Detection of DNA sequences as risk factors for HIV infection

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998014584A2 (fr) * 1996-10-01 1998-04-09 Yale University Compositions et procedes destines a la prevention et au diagnostic de l'ehrlichiose granulocytaire humaine
WO1998049312A2 (fr) * 1997-04-25 1998-11-05 Aquila Biopharmaceuticals, Inc. Acides nucleiques, proteines et modes d'utilisation d'erhlichia granulocyte

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998014584A2 (fr) * 1996-10-01 1998-04-09 Yale University Compositions et procedes destines a la prevention et au diagnostic de l'ehrlichiose granulocytaire humaine
WO1998049312A2 (fr) * 1997-04-25 1998-11-05 Aquila Biopharmaceuticals, Inc. Acides nucleiques, proteines et modes d'utilisation d'erhlichia granulocyte

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
ASANOVICH KRISTIN M ET AL: "Antigenic diversity of granulocytic Ehrlichia isolates from humans in Wisconsin and New York and a horse in California.", JOURNAL OF INFECTIOUS DISEASES, vol. 176, no. 4, 1997, pages 1029 - 1034, XP009008696, ISSN: 0022-1899 *
IJDO JACOB W ET AL: "Cloning of the gene encoding the 44-kilodalton antigen of the agent of human granulocytic Ehrlichiosis and characterization of the humoral response.", INFECTION AND IMMUNITY, vol. 66, no. 7, July 1998 (1998-07-01), pages 3264 - 3269, XP002236398, ISSN: 0019-9567 *
IJDO JACOB W ET AL: "The early humoral response in human granulocytic ehrlichiosis.", JOURNAL OF INFECTIOUS DISEASES, vol. 176, no. 3, 1997, pages 687 - 692, XP002237262, ISSN: 0022-1899 *
MURPHY CHERYL I ET AL: "Major antigenic proteins of the agent of human granulocytic ehrlichiosis are encoded by members of a multigene family.", INFECTION AND IMMUNITY, vol. 66, no. 8, August 1998 (1998-08-01), pages 3711 - 3718, XP002236397, ISSN: 0019-9567 *
PALMER G H ET AL: "The immunoprotective Anaplasma marginale major surface protein 2 is encoded by a polymorphic multigene family", INFECTION AND IMMUNITY, AMERICAN SOCIETY FOR MICROBIOLOGY. WASHINGTON, US, vol. 9, no. 62, 1 September 1994 (1994-09-01), pages 3808 - 3816, XP002074855, ISSN: 0019-9567 *
See also references of WO9952370A1 *
ZHI NING ET AL: "Multiple p44 genes encoding major outer membrane proteins are expressed in the human granulocytic ehrlichiosis agent.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 274, no. 25, 18 June 1999 (1999-06-18), pages 17828 - 17836, XP002236399, ISSN: 0021-9258 *

Also Published As

Publication number Publication date
AU3483599A (en) 1999-11-01
WO1999052370A1 (fr) 1999-10-21
EP1069827A1 (fr) 2001-01-24
CA2326717A1 (fr) 1999-10-21

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