EP1061800A4 - Zusammensetzungen und verfahren zur modulierung der vaskularisation - Google Patents
Zusammensetzungen und verfahren zur modulierung der vaskularisationInfo
- Publication number
- EP1061800A4 EP1061800A4 EP99912344A EP99912344A EP1061800A4 EP 1061800 A4 EP1061800 A4 EP 1061800A4 EP 99912344 A EP99912344 A EP 99912344A EP 99912344 A EP99912344 A EP 99912344A EP 1061800 A4 EP1061800 A4 EP 1061800A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- compositions
- methods
- vascularization
- modulating
- modulating vascularization
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
- G01N33/56972—White blood cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/44—Vessels; Vascular smooth muscle cells; Endothelial cells; Endothelial progenitor cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1858—Platelet-derived growth factor [PDGF]
- A61K38/1866—Vascular endothelial growth factor [VEGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/193—Colony stimulating factors [CSF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Vascular Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Gastroenterology & Hepatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Microbiology (AREA)
- Developmental Biology & Embryology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7726298P | 1998-03-09 | 1998-03-09 | |
US77262P | 1998-03-09 | ||
PCT/US1999/005130 WO1999045775A1 (en) | 1998-03-09 | 1999-03-09 | Compositions and methods for modulating vascularization |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1061800A1 EP1061800A1 (de) | 2000-12-27 |
EP1061800A4 true EP1061800A4 (de) | 2004-10-06 |
Family
ID=22137044
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP99912344A Withdrawn EP1061800A4 (de) | 1998-03-09 | 1999-03-09 | Zusammensetzungen und verfahren zur modulierung der vaskularisation |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1061800A4 (de) |
JP (2) | JP2002506008A (de) |
AU (1) | AU766238B2 (de) |
CA (1) | CA2322559C (de) |
WO (1) | WO1999045775A1 (de) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001094420A1 (en) | 2000-06-05 | 2001-12-13 | The Trustees Of Columbia University In The City Of New York | Identification and use of human bone marrow-derived endothelial progenitor cells to improve myocardial function after ischemic injury |
WO2001098344A2 (en) * | 2000-06-16 | 2001-12-27 | Curis, Inc. | Angiogenesis-modulating compositions and uses |
US7862810B2 (en) | 2000-07-31 | 2011-01-04 | New York Medical College | Methods and compositions for the repair and/or regeneration of damaged myocardium |
US20020061587A1 (en) | 2000-07-31 | 2002-05-23 | Piero Anversa | Methods and compositions for the repair and/or regeneration of damaged myocardium |
US7547674B2 (en) * | 2001-06-06 | 2009-06-16 | New York Medical College | Methods and compositions for the repair and/or regeneration of damaged myocardium |
CN1466463A (zh) * | 2000-09-13 | 2004-01-07 | 中外制药株式会社 | 缺血性疾病治疗剂 |
AU2742502A (en) * | 2000-10-30 | 2002-05-15 | Childrens Medical Center | Tissue-engineered vascular structures |
CA2467557A1 (en) * | 2001-11-19 | 2003-05-30 | Kyowa Hakko Kogyo Co., Ltd. | Agent which mobilizes multipotential stem cells from tissues to peripheral blood |
JPWO2003059375A1 (ja) * | 2002-01-17 | 2005-05-19 | 株式会社カルディオ | 組織再生複合療法 |
KR100562824B1 (ko) | 2002-03-20 | 2006-03-23 | 주식회사 바이로메드 | 유전자 발현효율이 높으며 간세포 성장인자의 두 가지이형체를 동시에 발현하는 하이브리드 간세포 성장인자유전자 |
US20030199464A1 (en) * | 2002-04-23 | 2003-10-23 | Silviu Itescu | Regeneration of endogenous myocardial tissue by induction of neovascularization |
US20040120930A1 (en) * | 2002-08-16 | 2004-06-24 | Schering Aktiengesellschaft | Gene therapy for critical limb ischemia with wild type or mutant eNOS |
AU2008200822A1 (en) * | 2002-08-22 | 2008-03-13 | The Cleveland Clinic Foundation | Stromal cell-derived factor-1 mediates stem cell homing and tissue regeneration in ischemic cardiomyopathy |
WO2008121719A1 (en) | 2007-03-30 | 2008-10-09 | The Cleveland Clinic Foundation | Method of treating ischemic disorders |
CN100366257C (zh) * | 2002-08-22 | 2008-02-06 | 克里夫兰诊所基金会 | 基质细胞衍生因子-1介导缺血性心肌病中干细胞归巢及组织再生 |
US20040037811A1 (en) * | 2002-08-22 | 2004-02-26 | The Cleveland Clinic Foundation | Stromal cell-derived factor-1 mediates stem cell homing and tissue regeneration in ischemic cardiomyopathy |
KR20050091720A (ko) * | 2002-12-13 | 2005-09-15 | 히사요시 후지와라 | 비허혈성 심부전 치료용 의약 조성물 |
US7695723B2 (en) * | 2002-12-31 | 2010-04-13 | Sygnis Bioscience Gmbh & Co. Kg | Methods of treating neurological conditions with hematopoietic growth factors |
KR20070008714A (ko) * | 2004-04-30 | 2007-01-17 | 오르버스네이치 메디칼 인코포레이티드 | 유전적으로-변형된 세포 포획용 코팅을 갖는 의료 장치 및이의 사용 방법 |
WO2006030887A1 (ja) * | 2004-09-17 | 2006-03-23 | Cellgentech, Inc. | 外用皮膚潰瘍治療剤 |
TW200637571A (en) * | 2005-01-11 | 2006-11-01 | Univ Nagoya Nat Univ Corp | CSF-containing remedy to be administered in low dose |
JPWO2006093172A1 (ja) * | 2005-02-28 | 2008-08-07 | 財団法人先端医療振興財団 | 成体幹細胞の体外増幅方法 |
WO2009062143A2 (en) | 2007-11-09 | 2009-05-14 | New York Medical College | Methods and compositions for the repair and/or regeneration of damaged myocardium using cytokines and variants thereof |
EP2227238A2 (de) | 2007-11-30 | 2010-09-15 | New York Medical College | Zusammensetzungen mit vaskulären und myozyten-vorläuferzellen und anwendungsverfahren davon |
US8512696B2 (en) | 2007-11-30 | 2013-08-20 | Autologous, Llc | Methods of isolating non-senescent cardiac stem cells and uses thereof |
WO2009073594A1 (en) | 2007-11-30 | 2009-06-11 | New York Medical College | Methods of reducing transplant rejection and cardiac allograft vasculopathy by implanting autologous stem cells |
CA2709398C (en) | 2007-12-14 | 2017-11-07 | The Cleveland Clinic Foundation | Use of stromal cell-derived factor 1 for promoting wound healing |
US20090258932A1 (en) | 2008-04-09 | 2009-10-15 | Viromed Co., Ltd. | Lyophilized DNA Formulations for Enhanced Expression of Plasmid DNA |
BR112012004395B8 (pt) | 2009-08-28 | 2021-05-25 | Cleveland Clinic Found | plasmídeo fator 1 derivado de célula de estroma (sdf-1) e preparação injetável compreendendo referido plasmídeo |
US9956265B2 (en) | 2011-04-26 | 2018-05-01 | Ajou University Industry-Academic Cooperation Foundation | Composition for aiding surgical procedures for treating ischemic vascular diseases |
KR101609690B1 (ko) * | 2011-04-26 | 2016-04-06 | 아주대학교산학협력단 | 허혈성 혈관 질환 치료시술 보조용 조성물 |
KR101336386B1 (ko) * | 2011-06-17 | 2013-12-04 | 전북대학교병원 | 림프관 생성 유도제 |
JP6240337B2 (ja) | 2013-10-22 | 2017-11-29 | バイロメッド カンパニー リミテッド | 肝細胞増殖因子の2つ以上のアイソフォームを利用した筋萎縮性側索硬化症の予防又は治療用組成物 |
EP3266459A4 (de) | 2015-03-18 | 2018-04-18 | Foundation for Biomedical Research and Innovation | Medizin zur behandlung und/oder verhütung von ischämischen krankheiten, verfahren zur verbesserung der angiogenesefördernden aktivität von zellen oder verfahren zur herstellung eines arzneimittels |
CA3106297A1 (en) | 2018-07-19 | 2020-01-23 | Helixmith Co., Ltd. | Lyophilized pharmaceutical compositions for naked dna gene therapy |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998019712A1 (en) * | 1996-11-08 | 1998-05-14 | St. Elizabeth's Medical Center Of Boston, Inc. | Methods for regulating angiogenesis |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4808042A (en) * | 1982-06-11 | 1989-02-28 | Electro-Plasma, Inc. | Powder feeder |
US4879282A (en) * | 1987-03-17 | 1989-11-07 | Saliba Jr Michael J | Medical application for heparin and related molecules |
US4808402A (en) * | 1987-05-29 | 1989-02-28 | Northwestern University | Method and compositions for modulating neovascularization |
US5880090A (en) * | 1997-09-19 | 1999-03-09 | The Hope Heart Institute | Treatment of vascular graft implants with G-CSF |
-
1999
- 1999-03-09 WO PCT/US1999/005130 patent/WO1999045775A1/en active IP Right Grant
- 1999-03-09 EP EP99912344A patent/EP1061800A4/de not_active Withdrawn
- 1999-03-09 AU AU30737/99A patent/AU766238B2/en not_active Ceased
- 1999-03-09 JP JP2000535201A patent/JP2002506008A/ja not_active Withdrawn
- 1999-03-09 CA CA2322559A patent/CA2322559C/en not_active Expired - Fee Related
-
2010
- 2010-07-12 JP JP2010157554A patent/JP2010265301A/ja active Pending
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998019712A1 (en) * | 1996-11-08 | 1998-05-14 | St. Elizabeth's Medical Center Of Boston, Inc. | Methods for regulating angiogenesis |
Non-Patent Citations (4)
Title |
---|
ASAHARA TAKAYUKI ET AL: "Vasculogenesis, developed by endothelial progenitor cells, has significant role in neovascularization in severe ischemia", CIRCULATION, vol. 96, no. 8 SUPPL., 21 October 1997 (1997-10-21), & 70TH SCIENTIFIC SESSIONS OF THE AMERICAN HEART ASSOCIATION; ORLANDO, FLORIDA, USA; NOVEMBER 9-12, 1997, pages I415 - I416, XP008033796, ISSN: 0009-7322 * |
FLAMME INGO ET AL: "Induction of vasculogenesis and hematopoiesis in vitro", DEVELOPMENT (CAMBRIDGE), vol. 116, no. 2, 1992, pages 435 - 439, XP002291992, ISSN: 0950-1991 * |
KALKA C ET AL: "Angiogenese und Vaskulogenese", HERZ, URBAN UND VOGEL, MUENCHEN, DE, vol. 25, no. 6, 2000, pages 611 - 622, XP002971995, ISSN: 0340-9937 * |
See also references of WO9945775A1 * |
Also Published As
Publication number | Publication date |
---|---|
EP1061800A1 (de) | 2000-12-27 |
WO1999045775A1 (en) | 1999-09-16 |
JP2010265301A (ja) | 2010-11-25 |
CA2322559C (en) | 2012-07-17 |
AU3073799A (en) | 1999-09-27 |
CA2322559A1 (en) | 1999-09-16 |
AU766238B2 (en) | 2003-10-09 |
JP2002506008A (ja) | 2002-02-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20001009 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: CARITAS ST. ELIZABETH'S MEDICAL CENTER OF BOSTON, |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: 7A 61K 35/28 B Ipc: 7A 61K 35/14 B Ipc: 7A 61K 38/19 B Ipc: 7A 61K 38/18 B Ipc: 7C 12Q 1/00 B Ipc: 7A 01N 37/18 A |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20040823 |
|
17Q | First examination report despatched |
Effective date: 20060926 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20160503 |