EP1060243A4 - Embryonische zelllinien oder stammzell-ähnliche zelllinien, die durch kerntransplantation zwischen verschiedenen spezies produziert wurden - Google Patents

Embryonische zelllinien oder stammzell-ähnliche zelllinien, die durch kerntransplantation zwischen verschiedenen spezies produziert wurden

Info

Publication number
EP1060243A4
EP1060243A4 EP99911062A EP99911062A EP1060243A4 EP 1060243 A4 EP1060243 A4 EP 1060243A4 EP 99911062 A EP99911062 A EP 99911062A EP 99911062 A EP99911062 A EP 99911062A EP 1060243 A4 EP1060243 A4 EP 1060243A4
Authority
EP
European Patent Office
Prior art keywords
embryonic
stem
cross
cell lines
lines produced
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99911062A
Other languages
English (en)
French (fr)
Other versions
EP1060243A1 (de
Inventor
James Robl
Jose Cibelli
Steven L Stice
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Massachusetts UMass
Original Assignee
University of Massachusetts UMass
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Massachusetts UMass filed Critical University of Massachusetts UMass
Publication of EP1060243A1 publication Critical patent/EP1060243A1/de
Publication of EP1060243A4 publication Critical patent/EP1060243A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2517/00—Cells related to new breeds of animals
    • C12N2517/04—Cells produced using nuclear transfer

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
EP99911062A 1998-03-02 1999-03-02 Embryonische zelllinien oder stammzell-ähnliche zelllinien, die durch kerntransplantation zwischen verschiedenen spezies produziert wurden Withdrawn EP1060243A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3294598A 1998-03-02 1998-03-02
US32945 1998-03-02
PCT/US1999/004608 WO1999045100A1 (en) 1998-03-02 1999-03-02 Embryonic or stem-like cell lines produced by cross-species nuclear transplantation

Publications (2)

Publication Number Publication Date
EP1060243A1 EP1060243A1 (de) 2000-12-20
EP1060243A4 true EP1060243A4 (de) 2005-03-09

Family

ID=21867727

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99911062A Withdrawn EP1060243A4 (de) 1998-03-02 1999-03-02 Embryonische zelllinien oder stammzell-ähnliche zelllinien, die durch kerntransplantation zwischen verschiedenen spezies produziert wurden

Country Status (9)

Country Link
EP (1) EP1060243A4 (de)
JP (1) JP2002505100A (de)
CN (1) CN1299408A (de)
AU (1) AU759322B2 (de)
BR (1) BR9908499A (de)
CA (1) CA2323094A1 (de)
IL (1) IL138201A0 (de)
NZ (1) NZ506808A (de)
WO (1) WO1999045100A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1214404A4 (de) * 1999-09-14 2003-09-03 Univ Massachusetts Durch spezies-übergreifende, nukleäre transplantation hergestellte embryo- oder stammzell-ähnliche zelllinien und verfahren zur verbesserung der embryoentwicklung durch genetische veränderung von donorzellen oder durch veränderung der gewebekultur
CA2388497A1 (en) * 1999-10-15 2001-04-26 Advanced Cell Technology, Inc. Method of producing differentiated progenitor cells by culturing morula or inner cell mass cells
EP1240318A4 (de) * 1999-12-20 2004-12-08 Univ Massachusetts DURCH SPEZIES-ÜBERGREIFENDE, NUKLEäRE TRANSPLANTATION HERGESTELLTE EMBRYONALE ODER STAMMZELLEN-ÄHNLICHE ZELLEN
US6576464B2 (en) 2000-11-27 2003-06-10 Geron Corporation Methods for providing differentiated stem cells
US6921665B2 (en) 2000-11-27 2005-07-26 Roslin Institute (Edinburgh) Selective antibody targeting of undifferentiated stem cells
AU2002250020A1 (en) * 2001-02-02 2002-08-19 Erik Forsberg Method of cloning transgenic mammalian animals using pseudonuclei
US20050066379A1 (en) * 2001-11-06 2005-03-24 Huizhen Sheng Preparing somatic embryo by utilizing rabbit oocyte
JP2005523685A (ja) * 2001-11-06 2005-08-11 上海第二医科大学 体細胞由来胚幹細胞及びそれらの分化子孫
AU2003230725A1 (en) * 2002-04-01 2003-10-20 Gtc Biotherapeutics, Inc. A method for selecting cell lines to be used for nuclear transfer in mammalian species
US10865383B2 (en) 2011-07-12 2020-12-15 Lineage Cell Therapeutics, Inc. Methods and formulations for orthopedic cell therapy
WO2013177228A1 (en) * 2012-05-22 2013-11-28 Loma Linda University Generation of integration/transgene-free stem cells
WO2015183920A2 (en) * 2014-05-28 2015-12-03 Children's Hospital Medical Center Methods and systems for converting precursor cells into gastric tissues through directed differentiation

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997037009A1 (en) * 1996-04-01 1997-10-09 University Of Massachusetts, A Public Institution Of Higher Education Of The Commonwealth Of Massachusetts, Represented By Its Amherst Campus Cultured inner cell mass cell lines derived from ungulate embryos
WO1998007841A1 (en) * 1996-08-19 1998-02-26 University Of Massachusetts Embryonic or stem-like cell lines produced by cross species nuclear transplantation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0973871A1 (de) * 1997-03-06 2000-01-26 Infigen, Inc. Verfahren zum klonieren von tieren
WO1999005266A2 (en) * 1997-07-26 1999-02-04 Wisconsin Alumni Research Foundation Trans-species nuclear transfer

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997037009A1 (en) * 1996-04-01 1997-10-09 University Of Massachusetts, A Public Institution Of Higher Education Of The Commonwealth Of Massachusetts, Represented By Its Amherst Campus Cultured inner cell mass cell lines derived from ungulate embryos
WO1998007841A1 (en) * 1996-08-19 1998-02-26 University Of Massachusetts Embryonic or stem-like cell lines produced by cross species nuclear transplantation

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
ARSENIAN S ET AL: "SERUM RESPONSE FACTOR IS ESSENTIAL FOR MESODERM FORMATION DURING MOUSE EMBRYOGENESIS", EMBO JOURNAL, OXFORD UNIVERSITY PRESS, SURREY, GB, vol. 17, no. 21, 2 November 1998 (1998-11-02), pages 6289 - 6299, XP002149683, ISSN: 0261-4189 *
BAGUTTI C, WOBUS AM, FASSLER R, WATT FM.: "Differentiation of embryonal stem cells into keratinocytes: comparison of wild-type and beta 1 integrin-deficient cells.", DEV BIOL., vol. 179, no. 1, 10 October 1996 (1996-10-10), pages 184 - 196, XP002298856 *
ROHWEDEL J ET AL: "Loss of beta-1 integrin function results in a retardation of myogenic, but an acceleration of neuronal, differentiation of embryonic stem cells in vitro", DEVELOPMENTAL BIOLOGY, ACADEMIC PRESS, NEW YORK, NY, US, vol. 201, 1998, pages 167 - 184, XP002963055, ISSN: 0012-1606 *
See also references of WO9945100A1 *

Also Published As

Publication number Publication date
CN1299408A (zh) 2001-06-13
EP1060243A1 (de) 2000-12-20
IL138201A0 (en) 2001-10-31
CA2323094A1 (en) 1999-09-10
AU759322B2 (en) 2003-04-10
WO1999045100A1 (en) 1999-09-10
JP2002505100A (ja) 2002-02-19
BR9908499A (pt) 2001-12-26
AU2979599A (en) 1999-09-20
NZ506808A (en) 2003-12-19

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

RIN1 Information on inventor provided before grant (corrected)

Inventor name: STICE, STEVEN, L.

Inventor name: CIBELLI, JOSE

Inventor name: ROBL, JAMES

RIC1 Information provided on ipc code assigned before grant

Ipc: 7C 12N 5/16 B

Ipc: 7C 12N 15/00 B

Ipc: 7A 01K 67/027 A

A4 Supplementary search report drawn up and despatched

Effective date: 20050124

17Q First examination report despatched

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17Q First examination report despatched

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RIN1 Information on inventor provided before grant (corrected)

Inventor name: STICE, STEVEN, L.

Inventor name: CIBELLI, JOSE

Inventor name: ROBL, JAMES

RIN1 Information on inventor provided before grant (corrected)

Inventor name: STICE, STEVEN, L.

Inventor name: CIBELLI, JOSE

Inventor name: ROBL, JAMES

STAA Information on the status of an ep patent application or granted ep patent

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Effective date: 20091001