Classifications

• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
  • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
  • A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
  • A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
  • A61J7/0481—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers working on a schedule basis
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
  • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
  • A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
  • A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
  • A61J7/0418—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers with electronic history memory
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
  • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
  • A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
  • A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
  • A61J7/0427—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers with direct interaction with a dispensing or delivery system
  • A61J7/0436—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers with direct interaction with a dispensing or delivery system resulting from removing a drug from, or opening, a container
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
  • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
  • A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
  • A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
  • A61J7/0427—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers with direct interaction with a dispensing or delivery system
  • A61J7/0445—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers with direct interaction with a dispensing or delivery system for preventing drug dispensing during a predetermined time period
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
  • A61J2205/00—General identification or selection means
  • A61J2205/70—Audible labels, e.g. for pre-recorded info or messages
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
  • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
  • A61M5/178—Syringes
• • G—PHYSICS
  • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
  • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
  • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
  • G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
  • G16H20/17—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection

Definitions

• the invention relates to a device for indicating an event of administra- tion, with an indicator for registering an event of administration of a medicament that should be administered usually regularly.
• the invention relates also to a method for indicating such administration.
• the application publication GB-2 179 919 discloses a medicament container which gives an alarm that can be turned off only by opening the container. Such a container can also contain a syringe or an ampoule.
• the application publication FR- 2 666 225 discloses an alarm system for a medicament container equipped with compartments for pills, tablets or corresponding orally administered doses, each compartment having a separate lid and being provided with a separate alarm. The alarm is turned off automati- cally within 15 seconds, and consequently no information is left in the container, whether the dose has been taken or not.
• US patent 4 417 889 discloses a system for preventing an extra dose integrated in the syringe, to prevent the use of the syringe a second time within a certain time interval after taking the dose, i.e. there is a kind of time lock. It is the fact that the syringe is operated with an electric motor that the detection of the administration and data storage is based on.
• US Patent 4 950 245 discloses a syringe intended for the use of a person having diabetes, an "injection pen", which can be used to administer a predetermined dose of insulin.
• the syringe has an integrated system with a sensor monitoring the progression of a pump rod inside the syringe and giving information to an electronic control unit for administering a correct dosage at the time of injection.
• the only alarm is an indication on the emptying of the reservoir to be expected.
• there has been no detector device or detection method that could be applied in a variety of syringes for controlling an event of administration. For example, diabetics must take a dose at regular intervals. Thus, it may remain uncertain whether a dose was really taken.
• the most common injection pens are of the type that a dose is administered by setting a push button back and pressing it at the time of injection, wherein it moves a piston in a medicament container forward the set distance.
• a dose is administered by setting a push button back and pressing it at the time of injection, wherein it moves a piston in a medicament container forward the set distance.
• the device according to the invention is primarily characterized in that it comprises a detector arranged to detect the mechanical movement of the dosage unit of medicament in connection with an event of administration. This movement can be the movement of a piston in the dosage unit or a part kinetically connected with it, or the release of the dosage unit from a support reserved for it.
• the method is primarily characterized in that the dosage unit is equipped with a separate, detachable indicating device, and when administering the dose, a specific detector means belonging to the indicating device is used to detect a mechanical movement, the event being automatically registered from the detector means in a memory.
• the invention does not require the use of injection pens based on electrical operation, as presented in the patents US- 4 417 889 and US-4 950 246, but it can be used in purely mechanical injection pens in which the administration is effected by a movement effected manually.
• Fig. 1 is a schematic view showing the principle of a first embodiment of the invention in connection with an injection pen
• Fig. 2 is a side view on the first embodiment of the invention in connection with an injection pen when assembled
• Fig. 3 shows the embodiment of Fig. 2 seen from a direction perpendicular to the direction of Fig. 2,
• Fig. 4 shows the first embodiment in an end view seen from the direction of arrow IN
• Fig. 5 is a side view on a second embodiment of the invention containing several dosage units
• Fig. 6 shows the embodiment of Fig. 5 seen from above
• Fig. 7 illustrates the use of the embodiment of Figs. 5 and 6,
• Fig. 8 shows another alternative of the embodiment of Figs. 2 to 4,
• Fig. 9 shows another alternative of the embodiment of Figs. 5 and 6, and
• Figs. 10 and 11 show further embodiments of the invention.
• Figure 1 shows a normal injection pen 1 and an indicating device 2 to be placed as a separate piece around it.
• the indicating device can have e.g. a sleeve-like or corresponding structure so that it can be fixed to an ordinary injection pen without making changes in the structure of the latter. For example, it can be pushed in the axial direction at the rear end of the injection pen around the same (arrow). Similarly, it can be equipped with a separate push-button piece 3 which can be fixed firmly around the normal push-button at the rear end of the injection pen.
• Figures 2 to 4 show a combination of the indicating device 2 and the injection pen in assembled state.
• the indicating device 2 surrounds the upper end of the injection pen underneath the press 3.
• the indicating device 2 comprises a battery 4 and a pair of indicators 5a, 5b.
• the first indicator 5a is arranged to indicate when it is time to administer a dose.
• the device has also a means 7 for detecting a movement in connection with administering the dose, in this case the movement of a part moving with respect to the body of the injection pen, such as the push-button or a piston or another injection means and/or parts kinetically connected with the same.
• a means 7 for detecting a movement in connection with administering the dose, in this case the movement of a part moving with respect to the body of the injection pen, such as the push-button or a piston or another injection means and/or parts kinetically connected with the same.
• a part 6 which is drawn back with the setting movement and presses a micro-switch present in the indicating device 2, acting as said detector means 7, during the pushing movement.
• the part 6 moving together with the movement of the piston can be e.g. a tube-like piece which is received in a space reserved for it in the body of the indicating device 2 and which can be of a transparent material.
• the first indicator 5a is shifted into a state in which it reports that a dose was administered, i.e. the alarm stops.
• information on the administration of the dose is stored in the device 1 , and if one attempts to set the injection pen again for administration within a certain time from this event, the second indicator 5b of the indicator pair gives a warning.
• the indicators 5a, 5b of the indicator pair can be e.g. visual indicators, such as indicator lights.
• the indicator lights can be realized in practice with LED's.
• the indicator lights are preferably of different colours, e.g. one green and the other red.
• an acoustic indicator can be arranged to give a sound signal, e.g. a suitable buzzer. This acoustic indicator is schematically indicated with the reference number 5c.
• the indicating device 2 is also equipped with a setting switch 8, which can be used to select the alarm time corresponding to the dosage intervals. Similarly, it is provided with a window 17, through which the dosage scale in the body of the injection pen can be seen.
• Figures 3 and 4 also show an electronics part 9 arranged on one side of the device 2 and also equipped with a space for a battery.
• the electronics part contains the couplings to the detector means 7, the memory functions required for registering the event, and the circuits required for the control of the alarms and the indicators.
• Figures 5 to 7 and 9 show another indicating device 2 applying the same inventive idea.
• the indicating device 2 is a piece separate from the injection pen, and in this case it forms a stand for two or more injection pens 1.
• the purpose of the stand is to control and monitor the administration of several doses to be taken during the day.
• To each injection pen 1 there is allotted a time of the day in the memory of the device telling when the injection should be taken.
• a visual indicator by the pen shows that the dose should be taken from the pen in question. Also, an acoustic alarm is given.
• the visual indicator by the pen remains, for a given time, for example until the beginning of the standby time of the same pen, in a state that shows that the dose has already been taken from the pen. This is indicated advantageously with an illuminated colour that can be easily detected.
• the indicator for the pen showing that a dose should be administered and the indicator showing that the dose has been taken can be different indicators which are turned “on” and "off”. It is, of course, possible to use physically the same indicator which changes its state, e.g. colour, according to the state of the pen in question.
• the operating principle is the same for each injection pen 1 to be monitored in the stand.
• the injection pens can be different in that they contain medicaments which act differently and which each should be administered at a certain time of a day. In the treatment of diabetes, the pens may contain different types of insulin.
• the stand shown in Fig. 5 has vertical recesses 10 for placing injection pens in an erected position in the stand.
• the main principle of operation is the same as in the embodiment of Figs. 1 to 3, and it is best illustrated in Fig. 6.
• Each injection pen 1 is allotted an indicator pair 5a, 5b of its own.
• the device is arranged to alarm in a certain order, wherein the first indicator 5a of the respective injection pen alarms that it is time to administer a dose from the injection pen in question.
• the indicating device 2 detects the removal of this injection pen 1 from the stand by an arrangement where it has a means 7 detecting the movement of the injection pen away from the stand in a suitable way.
• a suitable micro-switch operating on the contact principle e.g. a switch placed on the bottom of the respective recess 10.
• the state of the first, alarming indicator 5a is reset.
• the second indicator 5b is shifted to a state in which it indicates that the dose has been administered.
• visual indicators such as indicator lights. The light of the first indicator 5a can be turned off and the light of the second indicator 5b can be lit at the same time as a sign of removal of the injection pen. This can be realized in practice with LED's in the same way as in the embodiment of Figs. 1 and 2.
• the device 2 has, e.g. by the recesses 10 for receiving the injection pens, similar alarm setting switches 8 as described above, one for each injection pen 1. These can also be used to set the suitable time intervals for example in a way that one switch is used to set the time telling at what time of the day the alarm is to be given, and the next switches can be used to set the dosage intervals, i.e. the time to the next alarm.
• the figure shows a stand for five injection pens corresponding to five times of administration during a day. If there are fewer times of administration, the last space or spaces in the stand can be simply left empty.
• Fig. 6 shows a separate indicator panel 12 coupled to the stand with a connection cable 11 and equipped with indicator pairs 5a, 5b operating in a way identical with the indicator pairs in the stand but provided also with a supplementary acoustic indicator 5c, such as a buzzer, common to all the indicators.
• the device com- prises a mains transformer 13, a "power on” indicator 14 in the indicator panel, as well as a main switch 15 which is in the stand but which may also be in the indicator panel 12.
• FIG. 7 illustrates a way of using the device of Figs. 4 and 5.
• the injection pens 1 can be in a stand at a temperature suitable for them, for example in a refrigerator 16.
• the indicator panel can be brought with the connecting cable outside the refrigerator or a corresponding space, in which it reports the situation continuously. Thus, the administration situation can be monitored continuously, and the doses are kept at a lower temperature suitable for them.
• a refrigerator is not necessary if allowed by the indoor temperature or the stability of the medicament to be administered. In this case, there is no need for a separate panel brought outside the refrigerator either, but all the functions can be contained in the same device body.
• a separate indicator panel equipped with a connection cable may be useful in situations in which it is desirable to have the indicators in a visible place, even if the actual stand is not kept in a closed place.
• the injection pens kept in the stand may still have their own indicating devices 2 according to Figs. 1 to 4, wherein it is possible to register both the removal of the injection pen from the stand and the administration of the dose from this injection pen.
• Figure 8 shows another indicating device which is also suitable for use with a pen-type injection means.
• the device can be used to set a maximum of two injection times, which can give the alarm according to the need.
• a setting switch 8 is used to set the alarm times and to reset both timings. When the switch is pressed down a first time at the time 8 99/43283 PCT/FI99/00154
• the device beeps once with a buzzer 5c as a sign that the first alarm time is set.
• this time of day is set as the second alarm time, and the device beeps twice as a sign of this. If the switch is pressed after this, the device beeps three times as a sign that both the alarm times are already set. If the switch is pressed continuously for a certain time, e.g. for at least 3 seconds, both of the alarm times are reset. The device beeps in this event five times and returns to its initial state.
• the setting switch 8 is a simple one acting on pushing principle, and the timer of the device registers as the alarm time the time of day when the switch is pressed.
• the detector means 7 is a micro-switch detecting the movement of the piston in the injection pen, i.e. the loading and administration of an injection.
• the micro-switch projects out from the end of the device 2, and a push-button at the end of the pen, which may be an extension piece arranged around the push-button of a commercial pen according to Fig. 1 , presses the switch down in the normal position.
• the push-button is moved back and it releases the switch, and when the injection is administered after the setting, the push-button presses the micro-switch down again.
• Each timing has a standby time which starts an hour before the alarm time and ends two hours after it.
• the device beeps four times with the buzzer 5c. If the dose is administered not earlier than one hour before the selected alarm time, an alarm is unnecessary and will not be given.
• the injection pen is loaded again (that is, at least a second time) within the standby state of the dose, the device gives three sound signals with the buzzer 5c, thereby warning from taking the same injection twice.
• a visual indicator e.g. the indicator light 5 flashes at the pace of the sound signal. This warning signal will not be given at other times, so that e.g. the insulin container can be changed at that time without an alarm.
• the device registers the administration of a dose, when the pushbutton has been set backwards and it has returned forward, i.e. the micro-switch has returned to the initial state. For giving a warning against a double injection, the setting of the push-button backwards will be sufficient.
• the device can remind of administering the dose with the same alarm if the administration of the dose has not been registered within a certain time.
• the reminder can be repeated at given time intervals.
• Figure 9 shows an indicating device 2 intended for several dosage units 1.
• dosage unit specific setting switches 8 By pressing dosage unit specific setting switches 8, it is possible to set the alarm times and to reset the timings accordinglo the same principle as in the device of Fig. 8.
• the switch When the switch is pressed down (e.g. with a pointed tool, such as a pen) a first time, the device beeps once with the buzzer 5c as a sign that the alarm time is set. If the switch is pressed again, the device beeps four times as a sign that the alarm time is already set (error signal).
• the device beeps five times and switches off the alarm of that injection pen whose setting switch 8 was pressed.
• Each timing has a standby time which starts one hour before the alarm time and ends three hours after that.
• the administration of the injection is being monitored.
• the device alarms with a sound signal and a green light is lit at the correct injection pen.
• the green light can be lit already when the standby time begins before the actual alarm.
• the detector 7 in the stand of injection pens detects that the injection pen is lifted from the stand, i.e. an injection is administered.
• the green signal light is turned off and the red signal light is 10 O 99/43283 PCT/FI99/00154
• the device gives eight quick sound signals, thereby warning to take the same injection twice. This signal is not given at any other time, so that e.g. the insulin container can be exchanged during that time without causing an alarm.
• a short delay ca. 3 to 6 seconds
• the device may remind of administering a dose with the same alarm if an administration is not registered within a certain time, e.g. in four minutes. The reminder may be repeated at certain intervals.
• a special alarm function that is, if the injection pen has not been removed from the stand within a certain time, e.g. during the predetermined standby time, a special alarm is given that is different from the alarms of the indicators 5a and 5b. Moreover, such a special alarm can be triggered first after two injection pens intended to be used in succession have not been removed during the respective times.
• the alarm can be given as a remote alarm outside the home of the user via a fixed telephone network or by using wireless telecommunication, such as GSM technol- 11 99/43283 PCT/FI99/00154
• the detector means 7 can be arranged to operate by the contact prin- ciple, such as micro-switches, but it is also possible to use contactless movement sensors, such as optical or magnetic movement sensors, whereby it may be necessary to provide the part which moves in relation to another part in connection with the operation of administering a dose with a corresponding element, such as a ferrite or Hall element or an IR transmitter and receiver.
• a corresponding element such as a ferrite or Hall element or an IR transmitter and receiver.
• Figs. 5 to 7 and 9 can also be used for monitoring the administration of other types of doses than those injected from syringes.
• the stand is fitted for dosage units containing other types of medical doses, for example ampoules.
• Figures 10 and 11 show some further embodiments.
• an injection pen is equipped with an indicating device with a lid to be turned away from the top of the push-button. The movement of turning the lid can be detected with a detector means, to register a dose as administered.
• Figure 11 shows a simple housing for one injection pen, in which the pen can be inserted and pulled out to administer a dose. This housing can operate in a corresponding way as a stand intended for several pens, with the only difference that it is used for monitoring one dosage unit only, and the functions of the panel are integrated in the housing.
• the device is equipped with a latch that prevents the preparative measures for the administration, such as a switch or latch in the stand or in the housing, to prevent the turning of the lid shown in Fig. 10 or the removal of the injection pen from the stand or housing.
• This locking can be on for a certain precautionary time, which can start from the registration of an event of administration or end at a certain moment of time, e.g. as long as the predetermined allowance time (standby time) of the next administration starts or for a shorter time, e.g. until the end of the predetermined standby time.
• these possibilities 12 99/43283 PCT/FI99/00154
• the injection pens are intended to be placed, the ends with a pocket clip foremost, into their compartments 10, which have a shaped space, such as a widened portion made at the side of the recess for this purpose.
• a latch 18 which in the locking position projects out above the pocket clip and prevents the pulling out of the injection pen.
• the latch 18 is activated when the pen is inserted back and the administration of the dose is registered.
• a precautionary time can be arranged with any of the principles mentioned above.
• the latch is arranged to be opened at the latest when the standby time of the injection pen in question starts, i.e. when it is allowed to administer a dose from the pen.
• the latch operates preferably in such a way that energy must be brought to it to keep it in the locking position and in the state without energy it will be open, for example a magnetic latch which, upon switching off of the current, is withdrawn by the effect of a spring to the open position.
• a magnetic latch which, upon switching off of the current, is withdrawn by the effect of a spring to the open position.
• the indicating device particularly one to be attached to an injection pen, does not necessarily need to have an alarm and remind function, but it can be intended only to register the event of administration, for example in the case of a dose which is to be taken in connection with having a meal and which has no definite time of the day. On the other hand, in connection with such an effective insulin, it is particularly important to prevent a double dosage.
• the device can be implemented with normal electronic components, such as various sensors, sound and light indicators, a microprocessor, a timer, and a memory which is preferably a memory retaining its information in spite of a failure in the supply of current. These means are functionally coupled to each other to implement the functions of the device.
• the electronics of the device is, in its simplest form, arranged to register an administered dose, and the registration can, in its simplest form, be such that information about the event of administration is left in the device 2 without data on the quantity of the dose.
• the device in connection with the injection pen is equipped with a function that indicates the quantity of the dose, wherein the detector 13 O 99/43283 PCT/FI99/00154
• means must be capable of measuring the extent of the forward movement of the piston.
• the indicating device 2 to be fixed to an injection pen can be attached to it in several ways. If the injection pen in question is intended for permanent use, the device can be equipped with fixing screws pressed against the surface of the pen, or the device 2 can be attached from the side, wherein it has a turnable or loose fixing plate which is tightened against the device so that the pen is clamped in between. Also, the device 2 can be pushed around the pen in the longitudinal direction of the pen and fixed with a quick coupling, e.g. with a rotatable quick coupling acting by the pressing principle placed in the device 2 at the end proximal to the tip of the injection pen. This is suitable particularly for disposable pens which are discarded when the insulin container is empty and to which the device 2 should be easily attachable.
• the device to be fixed to the injection pen may be provided with a rechargable battery instead of a disposable battery.
• the battery can be placed with the injection pen in the charging stand. It can also be connected by means of a cable to a special portable power supply, and via the same cable it can be connected to a sound signalling apparatus with a good output capacity.
• the cable can be connected to the device 2 with a plug.
• the battery of the device 2 serves thus as reserve and produces the current required by the device if no separate battery is connected.
• the design of the indicating device 2 intended for several dosage units 1 can be different than that presented above.
• the dosage units 1 are presented above as being placed in an upright position, but they can also be in a inclined or in a horizontal position.
• the device may be provided with additional displays, such as close to each dosage unit 1 a numerical display showing the quantity of the dose and/or a numerical display showing the time of administration.
• the readings of the additional displays can naturally be changable.

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• Health & Medical Sciences (AREA)
• Engineering & Computer Science (AREA)
• Medical Informatics (AREA)
• Life Sciences & Earth Sciences (AREA)
• Animal Behavior & Ethology (AREA)
• General Health & Medical Sciences (AREA)
• Public Health (AREA)
• Veterinary Medicine (AREA)
• Bioinformatics & Cheminformatics (AREA)
• Infusion, Injection, And Reservoir Apparatuses (AREA)
• Medical Preparation Storing Or Oral Administration Devices (AREA)

Applications Claiming Priority (3)

Publications (1)

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Family Applications (1)

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Citations (3)

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• 1998
  • 1998-02-26 FI FI980447A patent/FI109272B/sv not_active IP Right Cessation
• 1999
  • 1999-02-26 BR BR9908153-9A patent/BR9908153A/pt not_active IP Right Cessation
  • 1999-02-26 JP JP2000533084A patent/JP2002504397A/ja active Pending
  • 1999-02-26 EE EEP200000480A patent/EE200000480A/xx unknown
  • 1999-02-26 AU AU26268/99A patent/AU763048B2/en not_active Ceased
  • 1999-02-26 WO PCT/FI1999/000154 patent/WO1999043283A1/en not_active Application Discontinuation
  • 1999-02-26 CA CA002321555A patent/CA2321555A1/en not_active Abandoned
  • 1999-02-26 EP EP99906281A patent/EP1056427A1/en not_active Withdrawn
• 2000
  • 2000-08-24 NO NO20004234A patent/NO20004234L/no not_active Application Discontinuation

Patent Citations (3)

Non-Patent Citations (1)

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