EP1053351A4 - Neue moleküle der tnf-rezeptorsuperfamilie und verwendungen dafür - Google Patents

Neue moleküle der tnf-rezeptorsuperfamilie und verwendungen dafür

Info

Publication number
EP1053351A4
EP1053351A4 EP99904304A EP99904304A EP1053351A4 EP 1053351 A4 EP1053351 A4 EP 1053351A4 EP 99904304 A EP99904304 A EP 99904304A EP 99904304 A EP99904304 A EP 99904304A EP 1053351 A4 EP1053351 A4 EP 1053351A4
Authority
EP
European Patent Office
Prior art keywords
tnf receptor
receptor superfamily
uses therefor
novel molecules
molecules
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99904304A
Other languages
English (en)
French (fr)
Other versions
EP1053351A1 (de
Inventor
Samantha J Busfield
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Millennium Pharmaceuticals Inc
Original Assignee
Millennium Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millennium Pharmaceuticals Inc filed Critical Millennium Pharmaceuticals Inc
Publication of EP1053351A1 publication Critical patent/EP1053351A1/de
Publication of EP1053351A4 publication Critical patent/EP1053351A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
EP99904304A 1998-01-27 1999-01-27 Neue moleküle der tnf-rezeptorsuperfamilie und verwendungen dafür Withdrawn EP1053351A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1419598A 1998-01-27 1998-01-27
US14195 1998-01-27
PCT/US1999/001679 WO1999037818A1 (en) 1998-01-27 1999-01-27 Novel molecules of the tnf receptor superfamily and uses therefor

Publications (2)

Publication Number Publication Date
EP1053351A1 EP1053351A1 (de) 2000-11-22
EP1053351A4 true EP1053351A4 (de) 2002-09-25

Family

ID=21764055

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99904304A Withdrawn EP1053351A4 (de) 1998-01-27 1999-01-27 Neue moleküle der tnf-rezeptorsuperfamilie und verwendungen dafür

Country Status (5)

Country Link
EP (1) EP1053351A4 (de)
JP (1) JP2002528046A (de)
AU (1) AU2472899A (de)
CA (1) CA2318743A1 (de)
WO (1) WO1999037818A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4357738B2 (ja) 1997-09-12 2009-11-04 アポテック エール エ デ− エス．アー． システインリッチなレセプターであるｔｒａｉｎ
AU2574200A (en) * 1999-02-19 2000-09-04 Toshio Kitamura Novel tnf receptor-like proteins
US6808902B1 (en) 1999-11-12 2004-10-26 Amgen Inc. Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules
TR201809008T4 (tr) 2001-06-26 2018-07-23 Amgen Fremont Inc Opgl ye karşi antikorlar.
CA2576193A1 (en) 2004-08-03 2006-02-16 Biogen Idec Ma Inc. Taj in neuronal function

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999011791A2 (en) * 1997-09-05 1999-03-11 University Of Washington Tumor necrosis factor family receptors and ligands, encoding nucleic acids and related binding agents
WO1999013078A1 (en) * 1997-09-12 1999-03-18 Biogen, Inc. Cysteine rich receptors-train
WO1999020644A1 (en) * 1997-10-18 1999-04-29 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
WO1999033967A2 (en) * 1997-12-29 1999-07-08 Regeneron Pharmaceuticals, Inc. Novel nucleic acid and polypeptide with homology to the tnf-receptors
WO1999033980A2 (en) * 1997-12-30 1999-07-08 Chiron Corporation Members of tnf and tnfr families
EP0990703A1 (de) * 1997-02-27 2000-04-05 Ono Pharmaceutical Co., Ltd. Neues polypeptid, dafür kodierende dna und deren verwendungen

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5395760A (en) * 1989-09-05 1995-03-07 Immunex Corporation DNA encoding tumor necrosis factor-α and -β receptors
US5656272A (en) * 1991-03-18 1997-08-12 New York University Medical Center Methods of treating TNF-α-mediated Crohn's disease using chimeric anti-TNF antibodies
US5698195A (en) * 1991-03-18 1997-12-16 New York University Medical Center Methods of treating rheumatoid arthritis using chimeric anti-TNF antibodies
US5447851B1 (en) * 1992-04-02 1999-07-06 Univ Texas System Board Of Dna encoding a chimeric polypeptide comprising the extracellular domain of tnf receptor fused to igg vectors and host cells

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0990703A1 (de) * 1997-02-27 2000-04-05 Ono Pharmaceutical Co., Ltd. Neues polypeptid, dafür kodierende dna und deren verwendungen
WO1999011791A2 (en) * 1997-09-05 1999-03-11 University Of Washington Tumor necrosis factor family receptors and ligands, encoding nucleic acids and related binding agents
WO1999013078A1 (en) * 1997-09-12 1999-03-18 Biogen, Inc. Cysteine rich receptors-train
WO1999020644A1 (en) * 1997-10-18 1999-04-29 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
WO1999033967A2 (en) * 1997-12-29 1999-07-08 Regeneron Pharmaceuticals, Inc. Novel nucleic acid and polypeptide with homology to the tnf-receptors
WO1999033980A2 (en) * 1997-12-30 1999-07-08 Chiron Corporation Members of tnf and tnfr families

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL, EBI [online] XP002205784, Database accession no. AA003356 *
See also references of WO9937818A1 *

Also Published As

Publication number Publication date
CA2318743A1 (en) 1999-07-29
EP1053351A1 (de) 2000-11-22
AU2472899A (en) 1999-08-09
JP2002528046A (ja) 2002-09-03
WO1999037818A1 (en) 1999-07-29

Similar Documents

Publication Publication Date Title
EP1109545A4 (de) Fc REZEPTORMODULATOREN UND DEREN VERWENDUNGEN
EP1085887A4 (de) Neuartige angiotensinrezeptor-modulatoren und deren verwendungen
AU2093499A (en) Members of tnf and tnfr families
PL339083A1 (en) Modification of rheological properties of polymers obtained using metalocenes
AU5733898A (en) Member of the hematopoietin receptor superfamily
GB2315016B (en) Shower screen
EP1064395A4 (de) Neue moleküle der g-protein-gekoppelten heptahelikalen rezeptoren-superfamilie und entsprechende anwendungen
IL109632A0 (en) Modulators of the function of the tnf receptors
EP1053351A4 (de) Neue moleküle der tnf-rezeptorsuperfamilie und verwendungen dafür
AU3668499A (en) Human receptor molecules
AU1242800A (en) Isolated vshk-1 receptor polypeptides and methods of use thereof
HUP0101612A3 (en) Modulators of the function of receptors of the tnf/ngf receptor family and other proteins
EP0958072A4 (de) Verbesserungen an schrauben und gewinden
MXPA02005731A (es) Moleculas similares al antagonista del receptor de interleucina-1 y usos de las mismas.
HUP0203689A3 (en) Interleukin-1 receptor antagonist-like molecules and uses thereof
TW363804U (en) Improvement on waterproof structure of the liquid crystal screen
GB2310505A8 (en) Polymer dispersed liquid crystal
MXPA02005775A (es) Moleculas ralacionadas con el antagonista del receptor de la interleucina-1 y usos de las mismas.
GB9625079D0 (en) Personal shower system
TW342763U (en) Clamping-positioning supplementary device of screw
GB2294391B (en) Screen for personal shower
GB2315410B (en) Shower screen
TW298805U (en) Modified structure of fixing element of angle adjustable hook
IL123758A0 (en) Modulators of the function of receptors of the TNF/NGF receptor family and other proteins
IL138383A0 (en) Modulators of the function of receptors of the tnf/ngf receptor family and other proteins

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20000828

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

RIC1 Information provided on ipc code assigned before grant

Free format text: 7C 12Q 1/68 A, 7C 12Q 1/02 B, 7C 12P 21/06 B, 7C 12N 5/00 B, 7A 61K 31/00 B, 7A 61K 38/00 B, 7C 07K 1/00 B, 7C 07K 16/00 B, 7C 07H 21/04 B, 7A 01K 67/027 B, 7C 07K 14/705 B, 7C 07K 14/715 B

A4 Supplementary search report drawn up and despatched

Effective date: 20020809

AK Designated contracting states

Kind code of ref document: A4

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20021129