EP1053351A4 - Novel molecules of the tnf receptor superfamily and uses therefor - Google Patents

Novel molecules of the tnf receptor superfamily and uses therefor

Info

Publication number
EP1053351A4
EP1053351A4 EP99904304A EP99904304A EP1053351A4 EP 1053351 A4 EP1053351 A4 EP 1053351A4 EP 99904304 A EP99904304 A EP 99904304A EP 99904304 A EP99904304 A EP 99904304A EP 1053351 A4 EP1053351 A4 EP 1053351A4
Authority
EP
European Patent Office
Prior art keywords
tnf receptor
receptor superfamily
uses therefor
novel molecules
molecules
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99904304A
Other languages
German (de)
French (fr)
Other versions
EP1053351A1 (en
Inventor
Samantha J Busfield
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Millennium Pharmaceuticals Inc
Original Assignee
Millennium Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millennium Pharmaceuticals Inc filed Critical Millennium Pharmaceuticals Inc
Publication of EP1053351A1 publication Critical patent/EP1053351A1/en
Publication of EP1053351A4 publication Critical patent/EP1053351A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
EP99904304A 1998-01-27 1999-01-27 Novel molecules of the tnf receptor superfamily and uses therefor Withdrawn EP1053351A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1419598A 1998-01-27 1998-01-27
US14195 1998-01-27
PCT/US1999/001679 WO1999037818A1 (en) 1998-01-27 1999-01-27 Novel molecules of the tnf receptor superfamily and uses therefor

Publications (2)

Publication Number Publication Date
EP1053351A1 EP1053351A1 (en) 2000-11-22
EP1053351A4 true EP1053351A4 (en) 2002-09-25

Family

ID=21764055

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99904304A Withdrawn EP1053351A4 (en) 1998-01-27 1999-01-27 Novel molecules of the tnf receptor superfamily and uses therefor

Country Status (5)

Country Link
EP (1) EP1053351A4 (en)
JP (1) JP2002528046A (en)
AU (1) AU2472899A (en)
CA (1) CA2318743A1 (en)
WO (1) WO1999037818A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69837606T2 (en) 1997-09-12 2008-02-14 Biogen Idec Ma Inc., Cambridge CYSTEIN RICH RECEPTORS TRAIN
WO2000049149A1 (en) * 1999-02-19 2000-08-24 Toshio Kitamura Novel tnf receptor-like proteins
US6808902B1 (en) 1999-11-12 2004-10-26 Amgen Inc. Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules
CN103232539B (en) 2001-06-26 2015-06-03 安姆根弗里蒙特公司 Antibodies to opgl
US7846438B2 (en) 2004-08-03 2010-12-07 Biogen Idec Ma Inc. Methods of promoting neurite outgrowth with soluble TAJ polypeptides

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999011791A2 (en) * 1997-09-05 1999-03-11 University Of Washington Tumor necrosis factor family receptors and ligands, encoding nucleic acids and related binding agents
WO1999013078A1 (en) * 1997-09-12 1999-03-18 Biogen, Inc. Cysteine rich receptors-train
WO1999020644A1 (en) * 1997-10-18 1999-04-29 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
WO1999033980A2 (en) * 1997-12-30 1999-07-08 Chiron Corporation Members of tnf and tnfr families
WO1999033967A2 (en) * 1997-12-29 1999-07-08 Regeneron Pharmaceuticals, Inc. Novel nucleic acid and polypeptide with homology to the tnf-receptors
EP0990703A1 (en) * 1997-02-27 2000-04-05 Ono Pharmaceutical Co., Ltd. Novel polypeptide, dna encoding the same and use thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5395760A (en) * 1989-09-05 1995-03-07 Immunex Corporation DNA encoding tumor necrosis factor-α and -β receptors
US5698195A (en) * 1991-03-18 1997-12-16 New York University Medical Center Methods of treating rheumatoid arthritis using chimeric anti-TNF antibodies
US5656272A (en) * 1991-03-18 1997-08-12 New York University Medical Center Methods of treating TNF-α-mediated Crohn's disease using chimeric anti-TNF antibodies
US5447851B1 (en) * 1992-04-02 1999-07-06 Univ Texas System Board Of Dna encoding a chimeric polypeptide comprising the extracellular domain of tnf receptor fused to igg vectors and host cells

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0990703A1 (en) * 1997-02-27 2000-04-05 Ono Pharmaceutical Co., Ltd. Novel polypeptide, dna encoding the same and use thereof
WO1999011791A2 (en) * 1997-09-05 1999-03-11 University Of Washington Tumor necrosis factor family receptors and ligands, encoding nucleic acids and related binding agents
WO1999013078A1 (en) * 1997-09-12 1999-03-18 Biogen, Inc. Cysteine rich receptors-train
WO1999020644A1 (en) * 1997-10-18 1999-04-29 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
WO1999033967A2 (en) * 1997-12-29 1999-07-08 Regeneron Pharmaceuticals, Inc. Novel nucleic acid and polypeptide with homology to the tnf-receptors
WO1999033980A2 (en) * 1997-12-30 1999-07-08 Chiron Corporation Members of tnf and tnfr families

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL, EBI [online] XP002205784, Database accession no. AA003356 *
See also references of WO9937818A1 *

Also Published As

Publication number Publication date
AU2472899A (en) 1999-08-09
CA2318743A1 (en) 1999-07-29
WO1999037818A1 (en) 1999-07-29
EP1053351A1 (en) 2000-11-22
JP2002528046A (en) 2002-09-03

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