EP1035849A4 - Inhibitors of farnesyl-protein transferase - Google Patents

Inhibitors of farnesyl-protein transferase

Info

Publication number
EP1035849A4
EP1035849A4 EP98960530A EP98960530A EP1035849A4 EP 1035849 A4 EP1035849 A4 EP 1035849A4 EP 98960530 A EP98960530 A EP 98960530A EP 98960530 A EP98960530 A EP 98960530A EP 1035849 A4 EP1035849 A4 EP 1035849A4
Authority
EP
European Patent Office
Prior art keywords
farnesyl
inhibitors
protein transferase
transferase
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP98960530A
Other languages
German (de)
French (fr)
Other versions
EP1035849A1 (en
Inventor
Terrence M Ciccarone
S Jane Desolms
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9807364.6A external-priority patent/GB9807364D0/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of EP1035849A1 publication Critical patent/EP1035849A1/en
Publication of EP1035849A4 publication Critical patent/EP1035849A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EP98960530A 1997-12-04 1998-11-30 Inhibitors of farnesyl-protein transferase Withdrawn EP1035849A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US6755297P 1997-12-04 1997-12-04
US67552P 1997-12-04
GBGB9807364.6A GB9807364D0 (en) 1998-04-06 1998-04-06 Inhibitors of farnesyl-protein transferase
GB9807364 1998-04-06
PCT/US1998/025325 WO1999027928A1 (en) 1997-12-04 1998-11-30 Inhibitors of farnesyl-protein transferase

Publications (2)

Publication Number Publication Date
EP1035849A1 EP1035849A1 (en) 2000-09-20
EP1035849A4 true EP1035849A4 (en) 2001-09-12

Family

ID=26313441

Family Applications (1)

Application Number Title Priority Date Filing Date
EP98960530A Withdrawn EP1035849A4 (en) 1997-12-04 1998-11-30 Inhibitors of farnesyl-protein transferase

Country Status (4)

Country Link
EP (1) EP1035849A4 (en)
AU (1) AU1611199A (en)
CA (1) CA2311921A1 (en)
WO (1) WO1999027928A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9902987D0 (en) 1999-08-24 1999-08-24 Astra Pharma Prod Novel compounds
US7211595B2 (en) 2000-11-30 2007-05-01 Abbott Laboratories Farnesyltransferase inhibitors
GB0104050D0 (en) 2001-02-19 2001-04-04 Astrazeneca Ab Chemical compounds
GB0107228D0 (en) 2001-03-22 2001-05-16 Astrazeneca Ab Chemical compounds
SE0103818D0 (en) 2001-11-15 2001-11-15 Astrazeneca Ab Chemical compounds
KR100432577B1 (en) 2002-02-08 2004-05-24 주식회사유한양행 A process for the preparation of imidazole derivatives
SE0301369D0 (en) 2003-05-09 2003-05-09 Astrazeneca Ab Chemical compounds

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997018813A1 (en) * 1995-11-22 1997-05-29 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
WO1997027852A1 (en) * 1996-01-30 1997-08-07 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
WO1997036900A1 (en) * 1996-04-03 1997-10-09 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
WO1997036584A1 (en) * 1996-04-03 1997-10-09 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5262537A (en) * 1993-03-19 1993-11-16 Anaquest, Inc. Derivatives of 4,5,6,7-tetrahydroimidazo-[4,5-c]pyridinyl-6-carboxylic acid

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997018813A1 (en) * 1995-11-22 1997-05-29 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
WO1997027852A1 (en) * 1996-01-30 1997-08-07 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
WO1997036900A1 (en) * 1996-04-03 1997-10-09 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
WO1997036584A1 (en) * 1996-04-03 1997-10-09 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO9927928A1 *

Also Published As

Publication number Publication date
EP1035849A1 (en) 2000-09-20
AU1611199A (en) 1999-06-16
CA2311921A1 (en) 1999-06-10
WO1999027928A1 (en) 1999-06-10

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