EP1021168A4 - Dispositif d'administration de microparticules ou de nanoparticules de polymeres - Google Patents

Dispositif d'administration de microparticules ou de nanoparticules de polymeres

Info

Publication number
EP1021168A4
EP1021168A4 EP98952243A EP98952243A EP1021168A4 EP 1021168 A4 EP1021168 A4 EP 1021168A4 EP 98952243 A EP98952243 A EP 98952243A EP 98952243 A EP98952243 A EP 98952243A EP 1021168 A4 EP1021168 A4 EP 1021168A4
Authority
EP
European Patent Office
Prior art keywords
particulate
nano
micro
delivery system
polymeric delivery
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP98952243A
Other languages
German (de)
English (en)
Other versions
EP1021168A1 (fr
Inventor
Ales Prokop
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vanderbilt University
Original Assignee
Vanderbilt University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vanderbilt University filed Critical Vanderbilt University
Publication of EP1021168A1 publication Critical patent/EP1021168A1/fr
Publication of EP1021168A4 publication Critical patent/EP1021168A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5115—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5161—Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5169—Proteins, e.g. albumin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5192—Processes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Optics & Photonics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
EP98952243A 1997-10-09 1998-10-09 Dispositif d'administration de microparticules ou de nanoparticules de polymeres Withdrawn EP1021168A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6294397P 1997-10-09 1997-10-09
US62943P 1997-10-09
PCT/US1998/021455 WO1999018934A1 (fr) 1997-10-09 1998-10-09 Dispositif d'administration de microparticules ou de nanoparticules de polymeres

Publications (2)

Publication Number Publication Date
EP1021168A1 EP1021168A1 (fr) 2000-07-26
EP1021168A4 true EP1021168A4 (fr) 2006-08-30

Family

ID=22045878

Family Applications (1)

Application Number Title Priority Date Filing Date
EP98952243A Withdrawn EP1021168A4 (fr) 1997-10-09 1998-10-09 Dispositif d'administration de microparticules ou de nanoparticules de polymeres

Country Status (3)

Country Link
EP (1) EP1021168A4 (fr)
AU (1) AU9799198A (fr)
WO (1) WO1999018934A1 (fr)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19810965A1 (de) * 1998-03-13 1999-09-16 Aventis Res & Tech Gmbh & Co Nanopartikel, Verfahren zu ihrer Herstellung und ihre Verwendung
WO2001001964A2 (fr) * 1999-06-23 2001-01-11 Sedum Laboratories, Inc. Micro-excipients de biomolecules a formulation ionique
WO2001047501A1 (fr) * 1999-12-29 2001-07-05 Nanodelivery, Inc. Systeme de distribution de medicament a regulation de permeabilite
WO2003030872A2 (fr) * 2001-10-12 2003-04-17 Elan Pharma International Ltd. Compositions combinant des caracteristiques de liberation immediate et de liberation prolongee
US20040014698A1 (en) * 2002-07-18 2004-01-22 Gonzalo Hortelano Oral administration of therapeutic agent coupled to transporting agent
ES2226567B1 (es) * 2003-06-20 2006-07-01 Universidad De Santiago De Compostela Nanoparticulas de acido hialuronico.
ES2246695B1 (es) 2004-04-29 2007-05-01 Instituto Cientifico Y Tecnologico De Navarra, S.A. Composicion estimuladora de la respuesta inmunitaria que comprende nanoparticulas a base de un copolimero de metil vinil eter y anhidrido maleico.
ES2246694B1 (es) 2004-04-29 2007-05-01 Instituto Cientifico Y Tecnologico De Navarra, S.A. Nanoparticulas pegiladas.
KR100604976B1 (ko) * 2004-09-03 2006-07-28 학교법인연세대학교 다작용기 리간드로 안정화된 수용성 나노입자
US7282194B2 (en) * 2004-10-05 2007-10-16 Gp Medical, Inc. Nanoparticles for protein drug delivery
WO2006091180A2 (fr) * 2005-02-25 2006-08-31 Ali Demir Sezer Systemes vecteurs du medicament multiparticulaire fucoidane
EP1871397A1 (fr) * 2005-03-17 2008-01-02 Cargill, Incorporated Compositions liquides avec glycosylaminoglycane pour applications liees a la sante
WO2007093451A2 (fr) * 2006-02-17 2007-08-23 Topass Gmbh Imagerie multimode utilisant une nanoparticule polymere a trois compartiments presentant une specificite cellulaire
CA2654593A1 (fr) * 2006-06-08 2007-12-13 Bayer Schering Pharma Aktiengesellschaft Nanoparticules polymeres solides fonctionnalisees pour applications diagnostiques et therapeutiques
KR20090041437A (ko) * 2006-08-17 2009-04-28 노파르티스 아게 나노입자 조성물
EP2070521A1 (fr) * 2007-12-10 2009-06-17 Bayer Schering Pharma Aktiengesellschaft Nanoparticules à surface modifiée
DE102007059752A1 (de) * 2007-12-10 2009-06-18 Bayer Schering Pharma Aktiengesellschaft Funktionalisierte, feste Polymernanopartikel enthaltend Epothilone
ES2341165B2 (es) * 2008-10-28 2010-10-27 Universidad De Santiago De Compostela Nanoparticulas de acido colominico y derivados.
ES2345806B1 (es) * 2009-03-30 2011-07-22 Universidad De Santiago De Compostela Sistemas nanoparticulares elaborados a base de polimeros anionicos para administrar moleculas bioactivas para uso cosmetico.
EP2366386A4 (fr) * 2008-10-28 2013-11-27 Univ Santiago Compostela Systèmes nanoparticulaires élaborés à base de polymères anioniques
ES2342588B2 (es) * 2008-10-28 2011-03-10 Universidade De Santiago De Compostela Sistemas nanoparticulares elaborados a base de polimeros anionicos.
WO2010100781A1 (fr) * 2009-03-06 2010-09-10 国立大学法人東京大学 Composition pour l'administration d'acide nucléique
BR112018074352B1 (pt) * 2016-06-01 2021-11-30 Infectious Disease Research Institute Partículas de nanoalume contendo um agente de dimensionamento
WO2017220615A1 (fr) * 2016-06-20 2017-12-28 Virbac Procédé et appareil destinés à préparer une composition de microparticules
CN113171355B (zh) * 2021-04-25 2022-07-19 华中农业大学 具有m细胞靶向的硫酸黏杆菌素自组装纳米颗粒、制备方法及应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0454044A2 (fr) * 1990-04-25 1991-10-30 Hoechst Aktiengesellschaft Produit pharmacologique contenant des composés de polyélectrolytes sous forme de microparticules et au moins un agent actif

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4933185A (en) * 1986-09-24 1990-06-12 Massachusetts Institute Of Technology System for controlled release of biologically active compounds
US5562909A (en) * 1993-07-12 1996-10-08 Massachusetts Institute Of Technology Phosphazene polyelectrolytes as immunoadjuvants

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0454044A2 (fr) * 1990-04-25 1991-10-30 Hoechst Aktiengesellschaft Produit pharmacologique contenant des composés de polyélectrolytes sous forme de microparticules et au moins un agent actif

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
See also references of WO9918934A1 *
TAYLOR WANG ET AL.: "An encapsulation system for the immunoisolation of pancreatic islets", NATURE BIOTECHNOLOGY., vol. 15, no. 4, 1997, USNATURE PUBLISHING GROUP, NEW YORK, NY., pages 358 - 362, XP008066998 *

Also Published As

Publication number Publication date
EP1021168A1 (fr) 2000-07-26
WO1999018934A1 (fr) 1999-04-22
AU9799198A (en) 1999-05-03

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